K. Hallows

发表

Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease.

Jonathan Wang, Deborah D. Chin, Christopher Poon, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery

Eun Ji Chung, Jonathan Wang, Deborah D. Chin, 2018, Nano Research.

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

S. Somlo, S. Somlo, Hui Li, 2011, Proceedings of the National Academy of Sciences.

Metformin Improves Relevant Disease Parameters in an Autosomal Dominant Polycystic Kidney Disease Mouse Model.

V. Mancino, Jessica Pham, Hui Li, 2021, American journal of physiology. Renal physiology.

Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2010, American journal of physiology. Renal physiology.

AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.

Simon C Watkins, Jay K Kolls, K. Hallows, 2010, American journal of respiratory cell and molecular biology.

AMP-activated Kinase Inhibits the Epithelial Na+ Channel through Functional Regulation of the Ubiquitin Ligase Nedd4-2*

K. Hallows, D. Pearce, D. Neumann, 2006, Journal of Biological Chemistry.

Emerging role of AMP-activated protein kinase in coupling membrane transport to cellular metabolism

K. Hallows, 2005, Current opinion in nephrology and hypertension.

Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells.

K. Hallows, J. Leith, S. F. Bliven, 1988, Radiation research.

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

M. Birnbaum, C. Thompson, K. Hallows, 2010, Cell.

A Randomized Clinical Trial of Metformin to Treat Autosomal Dominant Polycystic Kidney Disease

Kaleab Z. Abebe, S. Seliger, K. Hallows, 2018, American Journal of Nephrology.

Volume-activated chloride channels in HL-60 cells: potent inhibition by an oxonol dye.

K. Hallows, J. Arreola, P. Knauf, 1995, The American journal of physiology.

Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells.

Dennis Brown, K. Hallows, N. Pastor-Soler, 2008, American journal of physiology. Cell physiology.

SGLT 1 , a Novel Cardiac Glucose Transporter , Mediates Increased Glucose Uptake in PRKAG 2 Cardiomyopathy

Ferhaan Ahmad, K. Hallows, R. Alzamora, 2010 .

SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathy.

Ferhaan Ahmad, K. Hallows, N. Pastor-Soler, 2010, Journal of molecular and cellular cardiology.

Epithelial Sodium Channel Inhibition by AMP-activated Protein Kinase in Oocytes and Polarized Renal Epithelial Cells*

John P. Johnson, K. Hallows, D. Neumann, 2005, Journal of Biological Chemistry.

Regulation of Channel Gating by AMP-activated Protein Kinase Modulates Cystic Fibrosis Transmembrane Conductance Regulator Activity in Lung Submucosal Cells*

B. Kemp, K. Hallows, L. Witters, 2003, The Journal of Biological Chemistry.

Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells.

G. Kobinger, James M. Wilson, K. Hallows, 2003, American journal of physiology. Cell physiology.

Acute cell volume changes in anisotonic media affect F-actin content of HL-60 cells.

K. Hallows, P. Knauf, C. Packman, 1991, The American journal of physiology.

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.

A. Subramanya, K. Hallows, N. Pastor-Soler, 2015, The Journal of clinical investigation.

Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel*

A. Burlingame, Hui Li, K. Hallows, 2010, The Journal of Biological Chemistry.

Role of AMP-activated protein kinase in kidney tubular transport, metabolism, and disease

K. Hallows, N. Pastor-Soler, R. Rajani, 2017, Current opinion in nephrology and hypertension.

"First do no harm": kidney drug targeting to avoid toxicity in ADPKD.

K. Hallows, E. J. Chung, 2018, American journal of physiology. Renal physiology.

Association of Baseline Urinary Metabolic Biomarkers with ADPKD Severity in TAME-PKD Clinical Trial Participants

Kaleab Z. Abebe, S. Seliger, Hui Li, 2021, Kidney360.

Epithelial transport during septic acute kidney injury.

J. Kellum, K. Hallows, N. Pastor-Soler, 2014, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Renal Hypoxia Interactions between HIF-1 and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease

Hui Li, K. Hallows, N. Pastor-Soler, 2015 .

Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease.

Hui Li, K. Hallows, N. Pastor-Soler, 2015, American journal of physiology. Renal physiology.

Vacuolar H (cid:1) -ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase

Hui Li, K. Hallows, N. Pastor-Soler, 2010 .

Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase.

Hui Li, K. Hallows, N. Pastor-Soler, 2010, American journal of physiology. Renal physiology.

Akt recruits Dab2 to albumin endocytosis in the proximal tubule.

M. Birnbaum, Hui Li, K. Hallows, 2014, American journal of physiology. Renal physiology.

Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2) Regulation by 14-3-3 Protein Binding at Canonical Serum and Glucocorticoid Kinase 1 (SGK1) Phosphorylation Sites*

Allis S. Chien, K. Krasinska, Hui Li, 2011, The Journal of Biological Chemistry.

AMP-activated protein kinase inhibits KCNQ 1 channels through regulation of the ubiquitin ligase Nedd 4-2 in renal epithelial cells

K. Hallows, N. Pastor-Soler, Christy Smolak, 2010 .

AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells.

K. Hallows, N. Pastor-Soler, Christy Smolak, 2010, American journal of physiology. Renal physiology.

Functional Regulation of the Epithelial Na+ Channel by IκB Kinase-β Occurs via Phosphorylation of the Ubiquitin Ligase Nedd4-2*

John P. Johnson, Hui Li, K. Hallows, 2009, Journal of Biological Chemistry.

Mechanisms of ENaC regulation and clinical implications.

K. Hallows, V. Bhalla, Vivek Bhalla, 2008, Journal of the American Society of Nephrology : JASN.

Ex vivo kidney slice preparations as a model system to study signaling cascades in kidney epithelial cells.

K. Hallows, N. Pastor-Soler, B. Saitta, 2019, Methods in cell biology.

Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.

Hui Li, K. Hallows, G. Apodaca, 2011, American journal of physiology. Renal physiology.

AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system

K. Hallows, V. Deretic, M. Burge, 2021 .

Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells

John P. Johnson, Hui Li, K. Hallows, 2013, PloS one.

Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2016, American journal of physiology. Renal physiology.

PKA Regulates Vacuolar H+-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells*

Hui Li, K. Hallows, N. Pastor-Soler, 2010, The Journal of Biological Chemistry.

AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1.

D. Power, B. Kemp, Hui Li, 2013, American journal of physiology. Renal physiology.

AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2009, American journal of physiology. Cell physiology.

Extracorporeal therapy for dabigatran removal in the treatment of acute bleeding: a single center experience.

T. Nolin, M. Unruh, K. Hallows, 2013, Clinical journal of the American Society of Nephrology : CJASN.

Up-regulation of AMP-activated Kinase by Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Airway Epithelial Cells Mitigates Excessive Inflammation*

J. Clancy, P. Reynolds, K. Hallows, 2006, Journal of Biological Chemistry.

AMPK phosphorylation of the (cid:2) 1 Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells

Hui Li, K. Hallows, V. Bhalla, 2019 .

Regulation of Epithelial Na+ Transport by Soluble Adenylyl Cyclase in Kidney Collecting Duct Cells*

John P. Johnson, Hui Li, K. Hallows, 2009, Journal of Biological Chemistry.

AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney.

Hui Li, K. Hallows, N. Pastor-Soler, 2013, American journal of physiology. Renal physiology.

Opening lines of communication in the distal nephron.

K. Hallows, L. Satlin, T. Kleyman, 2013, The Journal of clinical investigation.

Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice

Jonathan Wang, V. Mancino, Jessica Pham, 2022, bioRxiv.

Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease

Jonathan Wang, Deborah D. Chin, Christopher Poon, 2022, bioRxiv.

Fundamentals of Epithelial Na+ Absorption

K. Hallows, D. Ilatovskaya, A. Staruschenko, 2020, Physiology in Health and Disease.

Chapter 2 Fundamentals of Epithelial Na + Absorption

K. Hallows, D. Ilatovskaya, A. Staruschenko, 2018 .

Fundamentals of Epithelial Na + Absorption

K. Hallows, D. Ilatovskaya, A. Staruschenko, 2016 .

Epithelial Na + Channels

K. Hallows, S. Sheng, T. Kleyman, 2013 .

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin*

Dennis Brown, K. Hallows, J. King, 2013, The Journal of Biological Chemistry.

Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase.

B. Kemp, K. Hallows, L. Witters, 2000, The Journal of clinical investigation.

Regulatory volume decrease in HL-60 cells: importance of rapid changes in permeability of Cl- and organic solutes.

K. Hallows, P. Knauf, 1994, The American journal of physiology.

Changes in cytoskeletal actin content, F‐actin distribution, and surface morphology during HL‐60 cell volume regulation

K. Hallows, P. Knauf, C. Packman, 1996, Journal of cellular physiology.

Baseline Characteristics and Patient-Reported Outcomes of ADPKD Patients in the Multicenter TAME-PKD Clinical Trial.

Kaleab Z. Abebe, S. Seliger, K. Hallows, 2020, Kidney360.

AMP-activated protein kinase regulation of kidney tubular transport

K. Hallows, N. Pastor-Soler, 2012, Current opinion in nephrology and hypertension.

Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors

A. McMahon, K. Hallows, N. Pastor-Soler, 2021, Nature Communications.

Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesis

A. McMahon, K. Hallows, N. Pastor-Soler, 2020, bioRxiv.

The urine/plasma electrolyte ratio: a predictive guide to water restriction.

S. Goldfarb, K. Hallows, E. Neilson, 2000, The American journal of the medical sciences.

In vitro delivery of mTOR inhibitors by kidney-targeted micelles for autosomal dominant polycystic kidney disease

Hui Li, K. Hallows, E. J. Chung, 2023, SLAS technology.

Activation of AMP‐activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness

J. Kellum, M. Pinsky, Hui Li, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

K. Hallows, V. Deretic, M. Burge, 2020, Molecular cell.

A1 adenosine receptor–stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation

Hui Li, K. Hallows, G. Apodaca, 2014, Molecular biology of the cell.

Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD

H. Heerspink, R. Gansevoort, Hui Li, 2022, Clinical journal of the American Society of Nephrology : CJASN.

Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD).

Kaleab Z. Abebe, K. Bae, C. Tao, 2021, Kidney international.

AMPK phosphorylation of the β1Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells.

Hui Li, K. Hallows, V. Bhalla, 2019, American journal of physiology. Renal physiology.

Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats

Hui Li, K. Hallows, D. Ilatovskaya, 2017, Front. Physiol..

Epithelial morphological reversion drives Profilin-1-induced elevation of p27kip1 in mesenchymal triple-negative human breast cancer cells through AMP-activated protein kinase activation

Hui Li, K. Hallows, P. Roy, 2015, Cell cycle.

beta1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells

Hui Li, K. Hallows, D. Neumann, 2019 .

β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells

Hui Li, K. Hallows, D. Neumann, 2018, The Journal of Biological Chemistry.

Muc1 is protective during kidney ischemia-reperfusion injury.

K. Hallows, J. Ho, N. Pastor-Soler, 2015, American journal of physiology. Renal physiology.

Muc 1 is protective during kidney ischemia-reperfusion injury

K. Hallows, J. Ho, N. Pastor-Soler, 2015 .

Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2016, American journal of physiology. Renal physiology.

AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system.

K. Hallows, V. Deretic, M. Burge, 2020, Autophagy.

Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy

J. Kellum, K. Hallows, N. Pastor-Soler, 2014, Critical Care.

MIF Matters: The Macrophage Migration Inhibitory Factor and Kidney Injury.

M. Unruh, K. Hallows, B. Wagner, 2019, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease.

D. Power, K. Hallows, N. Pastor-Soler, 2010, American journal of physiology. Renal physiology.

Association of Longitudinal Urinary Metabolic Biomarkers With ADPKD Severity and Response to Metformin in TAME-PKD Clinical Trial Participants

Kaleab Z. Abebe, S. Seliger, Hui Li, 2022, Kidney international reports.

RENAL ALLOGRAFT SURVIVAL IN AFRICAN-AMERICANS: INFLUENCE OF THE DUFFY BLOOD GROUP.

H. Feldman, K. Hallows, K. Brayman, 1999 .

Hemodialysis for the Treatment of Severe Accidental Hypothermia

K. Hallows, T. Singh, 2014, Seminars in dialysis.

AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR.

K. Hallows, J. King, A. Fitch, 2009, American journal of physiology. Cell physiology.

CFTR regulation by phosphorylation.

K. Hallows, J. King, R. Alzamora, 2011, Methods in molecular biology.

Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase*

A. Mehta, K. Hallows, J. King, 2012, The Journal of Biological Chemistry.

Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney

S. Jakobsen, B. Kemp, Hui Li, 2016, Scientific Reports.

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids

Y. Dou, Hui Li, K. Hallows, 2023, bioRxiv.

Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease

Jonathan Wang, Deborah D. Chin, Christopher Poon, 2023, bioRxiv.

Regulation of Villin by Wnt5a/Ror2 Signaling in Human Intestinal Cells

K. Hallows, R. Macleod, Rebecca Cheung, 2011, Front. Physio..