N. Bukanov

发表

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine

Laurie A. Smith, K. Klinger, O. Ibraghimov-Beskrovnaya, 2006, Nature.

Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

Laurie A. Smith, L. Meijer, G. Carlson, 2016, Human molecular genetics.

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

Laurie A. Smith, O. Ibraghimov-Beskrovnaya, D. Beier, 2006, Journal of the American Society of Nephrology : JASN.

A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease.

O. Fiehn, A. Chapman, R. Weiss, 2010, American journal of physiology. Renal physiology.

Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD

Laurie A. Smith, O. Ibraghimov-Beskrovnaya, B. Wang, 2016, Physiological reports.

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

Laurie A. Smith, L. Meijer, O. Ibraghimov-Beskrovnaya, 2012, Cell cycle.

Impaired formation of desmosomal junctions in ADPKD epithelia

O. Ibraghimov-Beskrovnaya, H. Husson, N. Bukanov, 2005, Histochemistry and Cell Biology.

Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.

L. Meijer, O. Ibraghimov-Beskrovnaya, T. Weimbs, 2018, American journal of physiology. Renal physiology.

Correction of cilia structure and function alleviates multi-organ pathology in Bardet–Biedl syndrome mice

Laurie A. Smith, K. Klinger, O. Ibraghimov-Beskrovnaya, 2020, Human molecular genetics.

Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

Laurie A. Smith, K. Klinger, O. Ibraghimov-Beskrovnaya, 2012, Human molecular genetics.

Functional Analysis of PKD 1 Transgenic Lines Reveals a Direct Role for Polycystin-1 in Mediating Cell-Cell Adhesion

O. Ibraghimov-Beskrovnaya, M. O'hare, N. Bukanov, 2003 .

Loss of GM 3 synthase gene , but not sphingosine kinase 1 , is protective against murine nephronophthisis-related polycystic kidney disease

Laurie A. Smith, K. Klinger, O. Ibraghimov-Beskrovnaya, 2012 .

Canine PKD1 is a single-copy gene: genomic organization and comparative analysis.

K. Klinger, O. Ibraghimov-Beskrovnaya, P. Manavalan, 2002, Genomics.

Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion.

O. Ibraghimov-Beskrovnaya, M. O'hare, N. Bukanov, 2003, Journal of the American Society of Nephrology : JASN.

Duplex DNA capture.

V. Demidov, N. Bukanov, D. Frank-Kamenetskii, 2000, Current issues in molecular biology.

Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

Laurie A. Smith, O. Ibraghimov-Beskrovnaya, B. Wang, 2010, Nature Medicine.

Cloneless genomic DNA analysis: an efficient and simple methods for de novo genomic sequencing projects and gap filling.

M. Oshimura, N. Bukanov, G. Nguyen, 2005, Biomolecular engineering.

CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis.

O. Ibraghimov-Beskrovnaya, H. Husson, N. Bukanov, 2016, American journal of physiology. Renal physiology.

Pkd1 and Nek8 mutations affect cell-cell adhesion and cilia in cysts formed in kidney organ cultures.

Laurie A. Smith, O. Ibraghimov-Beskrovnaya, H. Husson, 2008, American journal of physiology. Renal physiology.

Sevelamer restores bone volume and improves bone microarchitecture and strength in aged ovariectomized rats.

S. Vukicevic, N. Bukanov, Sarah E. Moreno, 2008, Endocrinology.

Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models

Yanqin Zhang, O. Ibraghimov-Beskrovnaya, H. Husson, 2022, Cells.

Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1.

K. Klinger, G. Landes, O. Ibraghimov-Beskrovnaya, 2000, Human molecular genetics.

PD-loop: a complex of duplex DNA with an oligonucleotide.

V V Demidov, P. Nielsen, M. Frank-Kamenetskii, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A modified two-step phage display selection for isolation of polycystin-1 ligands

K. Klinger, G. Landes, O. Ibraghimov-Beskrovnaya, 2000, Functional & Integrative Genomics.

Polycystic kidney diseases: From molecular discoveries to targeted therapeutic strategies

O. Ibraghimov-Beskrovnaya, N. Bukanov, 2007, Cellular and Molecular Life Sciences.

Serum and urinary biomarker signatures for rapid preclinical in vivo assessment of CDK inhibition as a therapeutic approach for PKD

O. Ibraghimov-Beskrovnaya, N. Bukanov, Sarah E. Moreno, 2008, Cell cycle.