B. Herbert

发表

Calcimimetics inhibit renal pathology in rodent nephronophthisis.

V. Gattone, R. Bacallao, N. Chen, 2011, Kidney international.

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death.

D. Corey, J. Shay, W. Wright, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.

J. Shay, W. Wright, R. Ramirez, 2001, Genes & development.

Small molecule, oligonucleotide-based telomerase template inhibition in combination with cytolytic therapy in an in vitro androgen-independent prostate cancer model.

D. Corey, J. Shay, B. Herbert, 2006, Urologic oncology.

Immortalization and characterization of osteoblast cell lines generated from wild‐type and Nmp4‐null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT)

A. Robling, B. Herbert, J. Bidwell, 2012, Journal of cellular physiology.

Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol

J. Shay, W. Wright, B. Herbert, 2006, Nature Protocols.

p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells.

J. Shay, W. Wright, B. Herbert, 2002, Oncogene.

p16INK4a inactivation is not required to immortalize human mammary epithelial cells

J. Shay, W. Wright, B. Herbert, 2002, Oncogene.

Calcimimetics inhibit renal pathology in rodent

V. Gattone, R. Bacallao, S. Moe, 2011 .

Cell-Type-Specific Responses to Chemotherapeutics in Breast Cancer

C. Perou, T. Sørlie, P. Lønning, 2004, Cancer Research.

Telomerase and breast cancer

J. Shay, W. Wright, B. Herbert, 2001, Breast Cancer Research.

Therapeutic Targets and Drugs I: Telomerase and Telomerase Inhibitors

B. Herbert, Erin M. Goldblatt, 2009 .

Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells*

K. Subbaramaiah, A. Dannenberg, R. Weiss, 2016, The Journal of Biological Chemistry.

Racial Differences in Cumulative Disadvantage Among Women and Its Relation to Health: Development and Preliminary Validation of the Cumulative Stress Inventory of Women's Experiences

B. Herbert, A. Storniolo, S. Bigatti, 2022, Health equity.

Abnormalities in CD 4k T-Lymphocyte Subsets in Inflammatory Rheumatic Diseases

Ľ., Dimaggio, A., 2004 .

Analysis of Telomeres and Telomerase

J. Shay, W. Wright, B. Herbert, 2003, Current protocols in cell biology.

Meeting report: second international meeting on quadruplex DNA.

J. Huppert, A. Phan, A. Lane, 2009, Biochimie.

Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor‐α via the p38 mitogen‐activated protein kinase pathway

B. Herbert, J. Rehman, M. Clauss, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

C. Harley, J. Shay, W. Wright, 2005, Oncogene.

Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.

B. Herbert, M. Mendonca, Erin M. Goldblatt, 2007, International journal of radiation oncology, biology, physics.

Disruption of telomere homeostasis as a new cancer treatment strategy

B. Herbert, 2009 .

The impact of telomeres and telomerase in cellular biology and medicine: it’s not the end of the story

B. Herbert, 2011, Journal of cellular and molecular medicine.

Overview of telomeres and the use of telomerase to compensate for telomere loss

J. Shay, W. Wright, B. Herbert, 2022 .

Oligonucleotide Conjugate GRN163L Targeting Human Telomerase as Potential Anticancer and Antimetastatic Agent

C. Harley, J. Shay, W. Wright, 2007, Nucleosides, nucleotides & nucleic acids.

Pharmaceutical regulation of telomerase and its clinical potential

B. Herbert, Brittney-Shea Herbert, Alyssa A Sprouse, 2011, Journal of cellular and molecular medicine.

Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells

J. Shay, W. Wright, R. Ramirez, 2003, Oncogene.

Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes.

Youngwook Kim, Z. Cui, Keunchil Park, 2011, ACS nano.

Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells.

B. Herbert, Alyssa A. Sprouse, 2014, Anticancer research.

An inhibitor of the mitotic kinase, MPS1, is selective towards pancreatic cancer cells

M. Korc, B. Herbert, Jae-Hoon Jeong, 2014 .

Aneuploidy and telomere attrition are independent determinants of crisis in SV40-transformed epithelial cells.

J. Shay, B. Herbert, Jiamei Yu, 2003, Cancer research.

A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers

Peter H. Baenziger, Steven M. Lipkin, Howard J. Edenberg, 2010, Oncotarget.

Telomerase immortalization of human mammary epithelial cells derived from a BRCA2 mutation carrier

R. Ashfaq, J. Shay, B. Herbert, 2006, Breast Cancer Research and Treatment.

Heritable one-hit events defining cancer prevention?

L. Kopelovich, B. Herbert, 2013, Cell cycle.

Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.

B. Herbert, T. Ozgurtas, Z. Dikmen, 2009, Biochimica et biophysica acta.

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

G. Vance, D. Schindelhauer, B. Herbert, 2012, Oncogene.

Phenotypic plasticity in normal breast derived epithelial cells

S. Badve, B. Herbert, M. Radovich, 2014, BMC Cell Biology.

p53 Protein Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression*

L. Kopelovich, K. Subbaramaiah, A. Dannenberg, 2014, The Journal of Biological Chemistry.

N-(4-hydroxyphenyl)retinamide activation of transforming growth factor-beta and induction of apoptosis in human breast cancer cells.

B. Herbert, B. G. Sanders, K. Kline, 1999, Nutrition and cancer.

Telomere dysfunction in aging and cancer.

B. Herbert, D. Gilley, Hiromi Tanaka, 2005, The international journal of biochemistry & cell biology.

Subsenescent Telomere Lengths in Fibroblasts Immortalized by Limiting Amounts of Telomerase*

Heidi S. Liss, J. Shay, W. Wright, 2000, The Journal of Biological Chemistry.

Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions

Stanley N Cohen, J. Shay, B. Herbert, 2004, Oncogene.

A peroxisome proliferator-activated receptor-gamma agonist and the p53 rescue drug CP-31398 inhibit the spontaneous immortalization of breast epithelial cells.

J. Shay, L. Kopelovich, L. Hynan, 2003, Cancer research.

Advances in breast cancer therapy and chemoprevention: current strategies and new approachesArticle

B. Herbert, 2003 .

Telomerase Template Antagonist GRN163L Disrupts Telomere Maintenance, Tumor Growth, and Metastasis of Breast Cancer

G. Sledge, S. Badve, B. Herbert, 2006, Clinical Cancer Research.

Effects of chemopreventive and antitelomerase agents on the spontaneous immortalization of breast epithelial cells.

J. Shay, L. Kopelovich, W. Wright, 2001, Journal of the National Cancer Institute.

Global gene expression of histologically normal primary skin cells from BCNS subjects reveals “single-hit” effects that are influenced by rapamycin

L. Kopelovich, M. Athar, B. Herbert, 2019, Oncotarget.

Medical genetics and epigenetics of telomerase

B. Herbert, Alyssa A. Sprouse, M. J. Fox, 2011, Journal of cellular and molecular medicine.

Factors impacting human telomere homeostasis and age-related disease

T. Reed, B. Herbert, N. Huda, 2008, Mechanisms of Ageing and Development.

The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel

Changyu Shen, Sergei M. Gryaznov, B. Herbert, 2009, Molecular Cancer Therapeutics.

The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cells

B. Herbert, Jillian E. Koziel, 2015, Breast Cancer Research and Treatment.

Altered expression of telomere‐associated genes in leukocytes among BRCA1 and BRCA2 carriers

Yunlong Liu, G. Sledge, B. Herbert, 2018, Molecular carcinogenesis.

Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors

J. Shay, B. Herbert, K. Pongracz, 2002, Oncogene.

Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab

B. Herbert, Erin M. Goldblatt, S. Gryaznov, 2009, Breast Cancer Research and Treatment.

Telomerase TemplateAntagonist GRN 163 L Disrupts Telomere Maintenance , Tumor Growth , andMetastasis of Breast Cancer

G. Sledge, S. Badve, B. Herbert, 2006 .

p53 Modulates Hsp90 ATPase Activity and Regulates Aryl Hydrocarbon Receptor Signaling

L. Kopelovich, K. Subbaramaiah, A. Dannenberg, 2014, Cancer Prevention Research.

A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker

Yehia Mechref, Yang Liu, Randy J Arnold, 2006, Proceedings of the National Academy of Sciences.

Novel Short Oligonucleotide Conjugates as Inhibitors of Human Telomerase

J. Shay, B. Herbert, K. Pongracz, 2003, Nucleosides, nucleotides & nucleic acids.

Development of a New Monochrome Multiplex qPCR Method for Relative Telomere Length Measurement in Cancer

B. Herbert, Hiromi Tanaka, S. Dey, 2018, Neoplasia.

Shared environmental factors associated with telomere length maintenance in elderly male twins

T. Reed, B. Herbert, N. Huda, 2007, Aging cell.

A Telomerase Immortalized Human Proximal Tubule Cell Line with a Truncation Mutation (Q4004X) in Polycystin-1

Peter R. Harris, A. Wandinger-Ness, V. Gattone, 2013, PloS one.

DNA Replication: Mammalian

B. Herbert, R. Hickey, L. Malkas, 2009 .

SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34+ Progenitor Cells

A. Malik, B. Herbert, G. Marsboom, 2017, Circulation.

Selective Inhibition of Pancreatic Ductal Adenocarcinoma Cell Growth by the Mitotic MPS1 Kinase Inhibitor NMS-P715

M. Korc, B. Herbert, Jae-Hoon Jeong, 2013, Molecular Cancer Therapeutics.

Small Molecule Therapeutics Selective Inhibition of Pancreatic Ductal Adenocarcinoma Cell Growth by the Mitotic MPS 1 Kinase Inhibitor NMSP 715

M. Korc, B. Herbert, Jae-Hoon Jeong, 2014 .

Erratum: Oligonucleotide N3′ → P5′ phosphoramidates as efficient telomerase inhibitors (Oncogene (2002) 21 (638-642))

J. Shay, B. Herbert, K. Pongracz, 2002 .

A peroxisome proliferator-activated receptor-gamma agonist and the p53 rescue drug CP-31398 inhibit the spontaneous immortalization of breast epithelial cells.

J. Shay, L. Kopelovich, L. Hynan, 2003, Cancer research.

Influence of Nano-Carrier Architecture on in Vitro siRNA Delivery Performance andinVivoBiodistribution:Polyplexesvs

B. Herbert, V. Bowman, P. Chipman, 2011 .