C. Boitard

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Clinical Spectrum Associated with Hepatocyte Nuclear Factor-1 Mutations

Christine Bellann-Chantelot, D. Chauveau, J. Gautier, 2004, Annals of Internal Medicine.

Long-Term Results of Early Cyclosporin Therapy in Juvenile IDDM

C. Boitard, P. Bougnères, J. Carel, 1996, Diabetes.

T Cell Response to Preproinsulin I and II in the Nonobese Diabetic Mouse1

C. Boitard, S. Muller, J. Briand, 2002, The Journal of Immunology.

Destruction of conditional insulinoma cell lines in NOD mice: A role for autoimmunity

C. Boitard, B. Thorens, P. Cattan, 2003, Diabetologia.

Diabetes mellitus after abdominal radiation therapy

C. Teinturier, C. Boitard, J. Timsit, 1995, The Lancet.

Effect of dietary protein on post-prandial glucose in patients with type 1 diabetes.

C. Boitard, A. Sola-Gazagnes, E. Larger, 2013, Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.

A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes

M. Vidaud, D. Eizirik, M. Colli, 2021, Frontiers in Immunology.

Low dose linomide in Type I juvenile diabetes of recent onset: a randomised placebo-controlled double blind trial

C. Boitard, P. Landais, P. Chatelain, 1998, Diabetologia.

Multiple DNA variant association analysis: application to the insulin gene region in type I diabetes.

P. Froguel, J. Bell, C. Julier, 1994, American journal of human genetics.

INSULINOSECRETION IN TYPE 2 DIABETES : CLINICAL ASPECTS C

C. Boitard, 2003 .

Adoptive T cell transfer of autoimmune nonobese diabetic mouse diabetes does not require recruitment of host B lymphocytes.

P. Bedossa, C. Boitard, H. Bazin, 1988, Journal of immunology.

[Covid-19 epidemic phases: Criteria, challenges and issues for the future].

F. Galibert, P. Debré, J. Allilaire, 2020, Bulletin de l'Academie nationale de medecine.

COVID-19 epidemic phases: Criteria, challenges and issues for the future☆

F. Galibert, P. Debré, J. Allilaire, 2020, Bulletin de l'Académie Nationale de Médecine.

Hypersensitivity to Insulin During Remissions in Cyclosporin-Treated IDDM Patients

C. Boitard, P. Landais, M. Beylot, 1993, Diabetes Care.

Plasma C-Peptide Levels and Clinical Remissions in Recent-Onset Type I Diabetic Patients Treated With Cyclosporin A and Insulin

C. Boitard, G. Feutren, J. Bach, 1990, Diabetes.

Identification of mimicry peptides based on sequential motifs of epitopes derived from 65‐kDa glutamic acid decarboxylase

P. van Endert, J. Bach, C. Boitard, 1998, European journal of immunology.

Factors associated with early remission of type I diabetes in children treated with cyclosporine.

M. Mihatsch, C. Boitard, P. Landais, 1988, The New England journal of medicine.

Oral insulin administration and residual (β-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial

C. Boitard, B. Charbonnel, P. Bougnères, 2000, The Lancet.

Preclinical Models to Evaluate the Human Response to Autoantigen and Antigen-Specific Immunotherapy in Human Type 1 Diabetes

C. Boitard, S. Luce, Pamela Houeiss, 2022, Frontiers in Endocrinology.

Genetic analysis of diabetes and insulitis in an interspecific cross of the nonobese diabetic mouse with Mus spretus.

G. Lathrop, J. Guénet, C. Julier, 1993, Proceedings of the National Academy of Sciences of the United States of America.

T Cell Recognition of Autoantigens in Human Type 1 Diabetes: Clinical Perspectives

C. Boitard, R. Mallone, V. Brezar, 2011, Clinical & developmental immunology.

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.

C. Boitard, S. Muller, J. Briand, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Abrogation of ICOS/ICOS ligand costimulation in NOD mice results in autoimmune deviation toward the neuromuscular system

T. Mak, H. Lassmann, C. Boitard, 2010, European journal of immunology.

Structure and function of the exocrine pancreas in patients with type 1 diabetes

R. Scharfmann, C. Boitard, R. Mallone, 2019, Reviews in Endocrine and Metabolic Disorders.

Normal insulin sensitivity during the late preclinical stage of type 1 diabetes.

C. Boitard, J. Timsit, R. Burcelin, 2004, Diabetes care.

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

P. Serup, G. Christofori, A. Peled, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Major histocompatibility class II genes polymorphism in insulin dependent diabetes mellitus with or without associated thyroid autoimmunity.

C. Boitard, J. Timsit, E. Bertin, 1998, Human immunology.

Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children.

C. Boitard, P. Bougnères, J. Carel, 1993 .

Limited Duration of Remission of Insulin Dependency in Children With Recent Overt Type I Diabetes Treated With Low-Dose Cyclosporin

C. Boitard, P. Landais, P. Bougnères, 1990, Diabetes.

Normal renal function 8 to 13 years after Cyclosporin A therapy in 285 diabetic patients

C. Boitard, J. Timsit, G. Feutren, 2002, Diabetes/metabolism research and reviews.

Relationship Between First-Phase Insulin Secretion and Age, HLA, Islet Cell Antibody Status, and Development of Type I Diabetes in 220 Juvenile First-Degree Relatives of Diabetic Patients

C. Boitard, J. Robert, I. Deschamps, 1991, Diabetes Care.

Evidence for antigen driven selection in two monoclonal auto-antibodies derived from nonobese diabetic mice.

C. Boitard, J. Bach, P. Marche, 1993, Molecular immunology.

Value of magnetic resonance imaging for evaluating muscle inflammation: insights from a new mouse model of myositis

P. Mulder, C. Boitard, Y. Allenbach, 2018, Neuropathology and Applied Neurobiology.

Heterogeneity of fetal growth in type 1 diabetic pregnancy.

D. Dubois-Laforgue, C. Boitard, J. Timsit, 2001, Diabetes & metabolism.

[ Absence of evidence of a possible connection vaccination for hepatitis B and the development of diabetes type 1. Report of a group of ALFEDIAM experts].

J. Bringer, C. Boitard, C. Thivolet, 1999, Diabetes & metabolism.

Predisposition to essential hypertension and renal hemodynamics in recent-onset insulin-dependent diabetic patients.

C. Boitard, J. Grünfeld, B. Lacour, 1992, Journal of the American Society of Nephrology : JASN.

Pancreatic Volume and Endocrine and Exocrine Functions in Patients With Diabetes

C. Boitard, E. Larger, L. Barbot-Trystram, 2011, Pancreas.

Zinc transporter (ZnT)8186–194 is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients

G. Bruno, F. Lemonnier, D. Levy, 2012, Diabetologia.

Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma.

P. Bedossa, C. Boitard, I. Gresser, 1991, Journal of autoimmunity.

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

C. Boitard, J. Bach, M. Dardenne, 1989, The Journal of experimental medicine.

A common stromal cell-derived factor-1 chemokine gene variant is associated with the early onset of type 1 diabetes.

C. Winkler, D. Dubois-Laforgue, C. Boitard, 2001, Diabetes.

β-cell Mass in Nondiabetic Autoantibody-Positive Subjects: An Analysis Based on the Network for Pancreatic Organ Donors Database.

C. Boitard, R. Mallone, E. Larger, 2016, The Journal of clinical endocrinology and metabolism.

Lymphocytes from diabetics suppress insulin releasein vitro

C. Boitard, R. Assan, J. Hamburger, 1981, Diabetologia.

The differentiation of the immune system towards anti-islet autoimmunity. Clinical prospects

C. Boitard, 1992, Diabetologia.

Inhibition of Insulin Release In Vitro Mediated by Mononuclear Cells From Diabetic Patients Treated With Cyclosporin A or Placebo

C. Boitard, G. Feutren, J. Bach, 1988, Diabetes.

Complement-fixing Islet Cell Antibodies from Some Diabetic Patients Alter Insulin Release In Vitro

C. Boitard, P. Sai, R. Assan, 1981, Diabetes.

Diabetes Mellitus and Autoimmunity

C. Boitard, J. Timsit, 1976, The Lancet.

Mutations in HFE, the Hemochromatosis Candidate Gene, in Patients With NIDDM

C. Boitard, J. Timsit, J. Bach, 1998, Diabetes Care.

Long in the shade, glucagon re‐occupies centre court

D. Accili, S. Seino, C. Boitard, 2011, Diabetes, obesity & metabolism.

Circadian rhythm‐related genes: implication in autoimmunity and type 1 diabetes

C. Boitard, B. Lebailly, U. Rogner, 2015, Diabetes, obesity & metabolism.

Altered dendritic cells (DC) might be responsible for regulatory T cell imbalance and autoimmunity in nonobese diabetic (NOD) mice.

C. Boitard, P. Marche, R. Berthier, 2002, European cytokine network.

Performance of liver biomarkers, in patients at risk of nonalcoholic steato-hepatitis, according to presence of type-2 diabetes

Y. Ngo, D. Thabut, D. Valla, 2019, European journal of gastroenterology & hepatology.

Insulin-dependent diabetes mellitus in non-DR3/non-DR4 subjects.

D. Dubois-Laforgue, C. Boitard, J. Timsit, 1997, Human immunology.

Pentamidine, a new diabetogenic drug in laboratory rodents

G. Reach, C. Boitard, R. Assan, 1983, Diabetologia.

Pancreas and islet transplantation in man.

L. Chatenoud, C. Boitard, J. Timsit, 1992, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Therapeutic immunosuppression in type I (insulin-dependent) diabetes

C. Boitard, G. Feutren, J. Bach, 1988 .

acDCs enhance human antigen-specific T-cell responses.

L. Zitvogel, N. Chaput, C. Boitard, 2011, Blood.

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes

E. Bonifacio, M. Knip, D. Dunger, 2022, Trials.

Cyclosporine delays but does not prevent clinical onset in glucose intolerant pre-type 1 diabetic children.

G. Eisenbarth, C. Boitard, P. Bougnères, 1996, Journal of autoimmunity.

Environmental Triggering of Type 1 Diabetes Autoimmunity

C. Boitard, S. Luce, Pamela Houeiss, 2022, Frontiers in Endocrinology.

Pancreatic islet autoimmunity.

C. Boitard, 2012, Presse medicale.

Single Insulin-Speci fi c CD 8 + T Cells Show Characteristic Gene Expression Pro fi les in Human Type 1 Diabetes

F. Lemonnier, J. Coste, C. Boitard, 2011 .

Expression of Preproinsulin-2 Gene Shapes the Immune Response to Preproinsulin in Normal Mice1

C. Boitard, J. Jami, S. Muller, 2004, The Journal of Immunology.

Normal Mice the Immune Response to Preproinsulin in Expression of Preproinsulin-2 Gene Shapes

C. Boitard, J. Jami, S. Muller, 2003 .

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice.

C. Boitard, J. Jami, S. Muller, 2003, The Journal of clinical investigation.

The diabetes type 1 locus Idd6 modulates activity of CD4+CD25+ regulatory T-cells.

P. Avner, C. Boitard, F. Lepault, 2006, Diabetes.

Passive transfer of flt‐3L‐derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)‐4 and IL‐10 in the spleen of recipient mice

C. Boitard, F. Lepault, M. Gagnerault, 2003, Clinical and experimental immunology.

Autoimmune diabetes: the role of the islets of Langerhans.

C. Boitard, F. Homo-Delarche, 1996, Immunology today.

Pancreatic Islet 13 Cells Drive T Cell-immune Responses in the Nonobese Diabetic Mouse Model By Etienne Larger, Chantal B6court, Jean Francois Bach,

C. Boitard, 1995 .

Control of diabetes in NOD mice by suppressor cells.

C. Boitard, J. Bach, M. Dardenne, 1990, Journal of autoimmunity.

In vivo prevention of thyroid and pancreatic autoimmunity in the BB rat by antibody to class II major histocompatibility complex gene products.

H. Mcdevitt, C. Boitard, S. Michie, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells.

C. Boitard, J. Bach, C. Carnaud, 1988, Proceedings of the National Academy of Sciences of the United States of America.

T-Cell Response to Proinsulin and Insulin in Type 1 and Pretype 1 Diabetes

C. Boitard, P. Bougnères, J. Guillet, 1999, Journal of Clinical Immunology.

High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.

P. van Endert, C. Boitard, J. Timsit, 1997, Journal of autoimmunity.

The circadian gene Arntl2 on distal mouse chromosome 6 controls thymocyte apoptosis

P. Avner, C. Boitard, F. Langa, 2017, Mammalian Genome.

Immunoregulated insulitis and slow-progressing type 1 diabetes after duodenopancreatectomy

F. Beuvon, C. Boitard, P. Faucher, 2021, Diabetologia.

Immunology of insulin-dependent mellitus.

C. Boitard, 1990, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Insulin and the prevention of insulin-dependent diabetes mellitus.

C. Boitard, J. Timsit, P. Bougnères, 1997, Diabetes & metabolism.

Heterogeneity of HLA genetic factors in IDDM susceptibility

J. Dausset, D. Cohen, C. Boitard, 2004, Immunogenetics.

Plasmacytoid dendritic cells license regulatory T cells, upon iNKT‐cell stimulation, to prevent autoimmune diabetes

C. Boitard, Y. Simoni, A. Lehuen, 2014, European journal of immunology.

Clinical characteristics of type 2 diabetes in patients with mutations of HFE.

D. Dubois-Laforgue, C. Boitard, J. Timsit, 2000, Diabetes & metabolism.

TAP1 and TAP2 transporter genes and predisposition to insulin dependent diabetes mellitus.

C. Boitard, J. Timsit, E. Bertin, 1992, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Immune mechanisms leading to type 1 insulin-dependent diabetes mellitus.

C. Boitard, J. Timsit, E. Larger, 1997, Hormone research.

The role of class II major histocompatibility complex antigens in autoimmune diabetes: animal models.

C. Boitard, J. Timsit, J. Bach, 1989, Journal of autoimmunity.

Mapping of the murine type 1 diabetes locus Idd20 by genetic interaction

P. Avner, C. Boitard, D. Vallois, 2006, Mammalian Genome.

Breast inflammatory gigantomastia in a context of immune-mediated diseases.

N. Brousse, C. Balleyguier, B. Eymard, 2005, The Journal of clinical endocrinology and metabolism.

The Spontaneous Autoimmune Neuromyopathy in ICOSL–/– NOD Mice Is CD4+ T-Cell and Interferon- Dependent

C. Boitard, C. Arnoult, L. Drouot, 2018 .

T-lymphocyte recognition of beta cells in type 1 diabetes: clinical perspectives.

C. Boitard, 2013, Diabetes & metabolism.

CD4+ Type II NKT Cells Mediate ICOS and Programmed Death-1–Dependent Regulation of Type 1 Diabetes

C. Boitard, D. Holmberg, Shashank Gupta, 2012, The Journal of Immunology.

Regulation of Type 1 DiabetesDependent - Programmed Death-1 and Type II NKT Cells Mediate ICOS + CD4

C. Boitard, D. Holmberg, Shashank Gupta, 2012 .

Role of beta-cells in type 1 diabetes pathogenesis.

C. Boitard, J. Carel, E. Larger, 2005, Diabetes.

T Cell Response to Preproinsulin I and II in the Nonobese Diabetic Mouse

C. Boitard, S. Muller, J. Briand, 2002 .

Recirculation, phenotype and functions of lymphocytes in mice treated with monoclonal antibody MEL‐14

C. Boitard, F. Lepault, M. Gagnerault, 1994, European journal of immunology.

Peptide specificity of high-titer anti-glutamic acid decarboxylase (GAD)65 autoantibodies.

P. van Endert, C. Granier, B. Pau, 1998, Immunology letters.

Insulin autoantibodies in non-obese diabetic (NOD) mice.

C. Boitard, J. Bach, C. Michel, 1989, Clinical and experimental immunology.

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR

Philippe Froguel, P. Froguel, M. Lathrop, 1993, Nature Genetics.

Three loci on mouse chromosome 6 influence onset and final incidence of type I diabetes in NOD.C3H congenic strains.

P. Avner, C. Boitard, E. Melanitou, 2001, Genomics.

No Major Role for the CTLA-4 Gene in the Association of Autoimmune Thyroid Disease With IDDM

C. Boitard, J. Timsit, E. Bertin, 1998, Diabetes.

Influence of a Non-NK Complex Region of Chromosome 6 on CD4+ Invariant NK T Cell Homeostasis1

P. Avner, C. Boitard, A. Herbelin, 2008, The Journal of Immunology.

Cell Homeostasis Invariant NK T + Chromosome 6 on CD 4 Influence of a Non-NK Complex Region of Herbelin and

P. Avner, C. Boitard, A. Herbelin, 2008 .

Insulin allergy: a diagnostic and therapeutic strategy based on a retrospective cohort and a case–control study

J. Coste, C. Boitard, P. Achenbach, 2022, Diabetologia.

the Nonobese Diabetic Mouse T Cell Response to Preproinsulin I and II in

C. Boitard, S. Muller, J. Briand, 2002 .

HLA class II-associated predisposition to insulin-dependent diabetes mellitus in a Polish population.

C. Boitard, S. Caillat-Zucman, A. Bratek, 1998, Human immunology.

Immunological effects of high dose administration of anti-CD4 antibody in rheumatoid arthritis patients.

C. Menkes, L. Chatenoud, C. Boitard, 1991, Journal of autoimmunity.

Contribution of DRB1*04 variants to predisposition to or protection from insulin dependent diabetes mellitus is independent of dq.

C. Boitard, J. Timsit, J. Bach, 1996, Journal of autoimmunity.

The Type 1 Diabetes Locus Idd6 Controls TLR1 Expression1

P. Avner, C. Boitard, C. Grimm, 2007, The Journal of Immunology.

The Type 1 Diabetes Locus

P. Avner, C. Boitard, C. Grimm, 2007 .

Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products.

C. Boitard, J. Bach, M. Portier, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Eating disorders and insulin‐dependent diabetes mellitus (IDDM): relationships with glycaemic control and somatic complications

C. Boitard, J. Timsit, G. Vila, 1998, Acta psychiatrica Scandinavica.

Nonneoplastic circulating sézary‐like cells in cutaneous T‐cell lymphoma. Ultrastructural, immunologic, and T‐cell receptor gene‐rearrangement studies

C. Boitard, J. Bach, L. Laroche, 1987, Cancer.

Cutaneous pheomorphic T cell lymphoma. Immunologic, virologic, and T-cell receptor gene rearrangement studies in one European case with initial pseudolymphoma presentation.

C. Boitard, Y. Prost, J. Bach, 1986, Journal of the American Academy of Dermatology.

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

C. Boitard, B. Charbonnel, P. Bougnères, 2000, Lancet.

Ambulatory 24-hour fast using flexible insulin therapy in patients with type 1 diabetes.

G. Slama, C. Boitard, A. Sola-Gazagnes, 2011, Diabetes & metabolism.

[Result of 3 years of screening for preclinical phase of juvenile insulin-dependent diabetes mellitus].

C. Boitard, P. Bougnères, J. Carel, 1990, Archives francaises de pediatrie.

Family study of linkage disequilibrium between TAP2 transporter and HLA class II genes. Absence of TAP2 contribution to association with insulin-dependent diabetes mellitus.

C. Boitard, J. Timsit, H. Garchon, 1995, Human immunology.

Anxiety and depressive disorders in an adult insulin-dependent diabetic mellitus (IDDM) population: relationships with glycaemic control and somatic complications

C. Boitard, J. Timsit, G. Vila, 1998, European Psychiatry.

Effect of cyclosporin A treatment on the production of antibody in insulin-dependent (type I) diabetic patients.

C. Boitard, G. Feutren, J. Bach, 1987, The Journal of clinical investigation.

Anti‐α/β T cell receptor monoclonal antibody provides an efficient therapy for autoimmune diabetes in nonobese diabetic (NOD) mice

P. Bedossa, C. Boitard, J. Bach, 1991 .

[Antioxidant enzymes in insulin-dependent diabetes in the child and adolescent].

C. Boitard, J. Robert, J. Jos, 1990, Diabete & metabolisme.

Cyclosporin A Suppresses Insulin Autoantibodies and Heterologous Insulin Antibodies in Type I Diabetic Children

C. Boitard, P. Bougnères, L. Castano, 1988, Diabetes.

Mechanisms and significance of HLA type I diabetes association.

C. Boitard, J. Timsit, H. Garchon, 1991, Research in immunology.

Insulin secretion: movement at all levels.

D. Steiner, E. Ferrannini, C. Boitard, 2002, Diabetes.

Studies on the thymus in nonobese diabetic mouse. I. Changes in the microenvironmental compartments.

C. Boitard, J. Bach, W. Savino, 1991, Laboratory investigation; a journal of technical methods and pathology.

Effect of Cyclosporin on Interleukin 2–Related T-Lymphocyte Parameters in IDDM Patients

L. Chatenoud, C. Boitard, G. Feutren, 1989, Diabetes.

Current concepts in autoimmunity.

C. Boitard, 1990, Current eye research.

Alexithymia in insulin-dependent diabetes mellitus is related to depression and not to somatic variables or compliance.

R. Dardennes, J. Guelfi, C. Boitard, 2003, Journal of psychosomatic research.

Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.

C. Boitard, R. Berthier, J. Morin, 2003, Cellular immunology.

Impact of treatment on islet function in type 2 diabetes.

D. Steiner, E. Ferrannini, C. Boitard, 2004, Diabetes.

Inhibition of type 1 diabetes by upregulation of the circadian rhythm-related aryl hydrocarbon receptor nuclear translocator-like 2

P. Avner, C. Boitard, N. Prevot, 2010, Immunogenetics.

T-cell reactivity to 38 kD insulin-secretory granule protein in patients with recent onset type 1 diabetes

E. Bonifacio, S. Arden, C. Boitard, 1994, Journal of endocrinological investigation.

Monoclonal antibodies: probes for studying experimental autoimmunity in animals.

C. Boitard, J. Timsit, J. Bach, 1991, Research in immunology.

Therapy of Autoimmune Diseases with Monoclonal Antibodies to Class II Major Histocompatibility Complex Antigens: The Role of T Lymphocytes

C. Boitard, J. Bach, 1988 .

Insulin secretion in type 2 diabetes: clinical aspects.

C. Boitard, 2002, Diabetes & metabolism.

HLA Class I Epitope Discovery in Type 1 Diabetes

M. Peakman, C. Boitard, T. Tree, 2006, Annals of the New York Academy of Sciences.

Evidence of CD4 + regulatory T cells in the non-obese diabetic male mouse

C. Boitard, J. Bach, P. Sempé, 1994, Diabetologia.

Islet cell antibody heterogeneity among Type 1 (insulin-dependent) diabetic patients

C. Boitard, J. Timsit, J. Bach, 1992, Diabetologia.

Anti-Bovine Serum Albumin Antibodies: Genetic Heterogeneity and Clinical Relevance in Adult-Onset IDDM

C. Boitard, J. Timsit, J. Bach, 1995, Diabetes Care.

Aberrant Distribution of CD4 and CD8 Lymphocyte Subsets in Recent-Onset IDDM Patients: Effect of Cyclosporin

L. Chatenoud, C. Boitard, J. Timsit, 1993, Diabetes.

Experimental immunoprevention of type I diabetes mellitus.

C. Boitard, J. Timsit, J. Bach, 1991, Diabetes/metabolism reviews.

B-cell responses in autoimmune diseases.

C. Boitard, 1992, Current opinion in immunology.

Anti-pancreatic immunity. In vitro studies of cellular and humoral immune reactions directed toward pancreatic islets.

C. Boitard, R. Assan, P. Saï, 1984, Clinical and experimental immunology.

Factors associated with the presence of glutamic acid decarboxylase and islet antigen-2 autoantibodies in patients with long-standing type 1 diabetes.

D. Dubois-Laforgue, C. Boitard, J. Timsit, 2013, Diabetes & metabolism.

Immunology and diabetes workshop: Report on the third international (Stage 3) workshop on the standardisation of cytoplasmic islet cell antibodies

E. Bonifacio, C. Boitard, G. Bottazzo, 1988, Diabetologia.

Downregulation of the circadian rhythm related gene Arntl2 suppresses diabetes protection in Idd6 NOD.C3H congenic mice

P. Avner, C. Boitard, U. Rogner, 2010, Clinical and experimental pharmacology & physiology.

A new monoclonal antibody recognizing the amino‐terminal consensus sequence of vertebrate intermediate filament proteins

F. Gros, C. Boitard, J. Bach, 1989, FEBS letters.

Cyclosporin A Does Not Delay Insulin Dependency in Asymptomatic IDDM Patients

C. Boitard, J. Timsit, J. Robert, 1995, Diabetes Care.

Role of infiltrating T cells for impaired glucose metabolism in pancreatic islets isolated from non-obese diabetic mice

C. Boitard, D. Eizirik, S. Sandler, 1992, Diabetologia.

Course of pancreatic beta cell destruction in prediabetic NOD mice: a histomorphometric evaluation.

M. Toublanc, C. Boitard, X. Debussche, 1994, Diabete & metabolisme.

POEMS syndrome presenting as systemic sclerosis. Clinical and pathologic study of a case with microangiopathic glomerular lesions.

C. Boitard, L. Noel, J. Bach, 1988, The American journal of medicine.

Diagnosing Diabetic Foot Osteomyelitis in Patients Without Signs of Soft Tissue Infection by Coupling Hybrid 67Ga SPECT/CT With Bedside Percutaneous Bone Puncture

Benjamin A Lipsky, C. Boitard, E. Larger, 2013, Diabetes Care.

The immunology of diabetes mellitus

P. Avner, C. Boitard, 1991, Nature.

Viral infection prevents diabetes by inducing regulatory T cells through NKT cell–plasmacytoid dendritic cell interplay

C. Boitard, M. V. von Herrath, R. Mallone, 2011, The Journal of experimental medicine.

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

K. Clément, J. McCluskey, J. Rossjohn, 2015, The Journal of clinical investigation.

An 8-bp deletion in mNOTCH4 intron 10 leads to its retention in mRNA and to synthesis of a truncated protein.

A. Benraiss, I. Laurendeau, C. Boitard, 2005, Experimental cell research.

Evidence for the presence of insulin-dependent diabetes-associated alleles on the distal part of mouse chromosome 6.

P. Avner, M. Lathrop, C. Boitard, 1998, Genome research.

Role of β-Cells in Type 1 Diabetes Pathogenesis

C. Boitard, J. Carel, E. Larger, 2005 .

Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus.

C. Boitard, J. Timsit, H. Garchon, 1992, The Journal of clinical investigation.

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

G. Lathrop, J. Rotter, P. Froguel, 1991, Nature.

High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q.

R. Spielman, J. Rotter, C. Julier, 1991, American journal of human genetics.

HLA class II allele and haplotype distribution in a population from central Poland.

C. Boitard, S. Caillat-Zucman, A. Bratek, 1998, European journal of immunogenetics.

IDDM: an islet or an immune disease?

J. Bach, C. Boitard, J. Timsit, 1994, Diabetologia.

Life table analysis of the risk of Type 1 (insulin-dependent) diabetes mellitus in siblings according to islet cell antibodies and HLA markers

C. Boitard, J. Robert, M. Busson, 1992, Diabetologia.

Autoantibodies against pancreatic beta-cells: characterization by western blot analysis in the non-obese diabetic (NOD) mouse.

C. Boitard, J. Bach, M. Portier, 1992, Journal of autoimmunity.

Neonatal induction of allogeneic tolerance prevents T cell‐mediated autoimmunity in NOD mice

C. Boitard, J. Bach, C. Carnaud, 1989, European journal of immunology.

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells

C. Boitard, J. Bach, C. Carnaud, 1987, The Journal of experimental medicine.

In vitro inhibition of pancreatic B cell function by lymphocytes from diabetics with associated autoimmune diseases: a T cell phenomenon.

L. Chatenoud, C. Boitard, M. Debray-Sachs, 1982, Journal of immunology.

Potential Role of IL-17-Producing iNKT Cells in Type 1 Diabetes

C. Boitard, D. Dubois-Laforgue, E. Larger, 2014, PloS one.

Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity

Y. Yazdanpanah, J. Timsit, M. Si-Tahar, 2021, Nature Immunology.

Absence of primary association between DM gene polymorphism and insulin-dependent diabetes mellitus or celiac disease.

C. Boitard, J. Timsit, J. Bach, 1996, Human immunology.

Lack of L‐selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel‐14 antibody treatment

C. Boitard, H. Bazin, F. Lepault, 1995, European journal of immunology.

Pancreatic islet beta cells drive T cell-immune responses in the nonobese diabetic mouse model

C. Boitard, J. Bach, E. Larger, 1995, The Journal of experimental medicine.

Are "activated" macrophages cytotoxic against normal cells?

C. Boitard, R. Assan, J. Hamburger, 1981, Transplantation proceedings.

Nephrotoxicity of cyclosporine in autoimmune diseases.

C. Boitard, J. Grünfeld, T. Hannedouche, 1990, Advances in nephrology from the Necker Hospital.

Beyond the hormone: insulin as an autoimmune target in type 1 diabetes.

C. Boitard, R. Mallone, J. Carel, 2011, Endocrine reviews.

Pathogenesis of IDDM: immune regulation and induction of immune tolerance in the NOD mouse.

C. Boitard, J. Timsit, J. Bach, 1993, Autoimmunity.

Protection from insulin‐dependent diabetes mellitus is linked to a peptide transporter gene

C. Boitard, J. Timsit, E. Bertin, 1993, European journal of immunology.

Follow-up of subjects with isolated and persistent anti-core (anti-p24 or anti-p17) antibodies to HIV.

J. Nicolas, C. Boitard, G. Lucotte, 1988, AIDS.

Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes

F. Lemonnier, J. Coste, C. Boitard, 2011, Diabetes.

Antigen-Based Immune Therapeutics for Type 1 Diabetes: Magic Bullets or Ordinary Blanks?

C. Boitard, R. Mallone, S. Culina, 2011, Clinical & developmental immunology.

Androgen producing adrenal adenoma. Report on a case associated with hyperparathyroidism

P. Guillausseau, C. Boitard, L. Cédard, 1987, Journal of endocrinological investigation.

Feedback-mediated reduction in glomerular filtration during acetazolamide infusion in insulin-dependent diabetic patients.

C. Boitard, J. Grünfeld, B. Lacour, 1991, Clinical science.

Outcome of SARS-CoV-2 infection linked to MAIT cell activation and cytotoxicity: evidence for an IL-18 dependent mechanism

Y. Yazdanpanah, J. Timsit, C. Boitard, 2020, medRxiv.

Changes in MicroRNA Expression Contribute to Pancreatic β-Cell Dysfunction in Prediabetic NOD Mice

P. Meda, C. Boitard, R. Regazzi, 2012, Diabetes.

Insulin-dependent diabetes and human leucocyte antigens.

C. Boitard, J. Timsit, S. Caillat-Zucman, 1997, Diabetes & Metabolism.

Hyperparathyroidism in a patient with autoimmune polyglandular syndrome.

C. Boitard, E. Larger, N. Fabien, 2008, Internal medicine.

Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients.

B. Mach, J. Elion, C. Boitard, 1992, Human immunology.

Assessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays

E. Bonifacio, Å. Lernmark, W. Scherbaum, 1990, Diabetologia.

O825 - Immunogenetics of IDDM in non-DR3/non-DR4 patients

C. Boitard, J. Timsit, S. Caillat-Zucman, 1996 .

Anti-alpha/beta T cell receptor monoclonal antibody provides an efficient therapy for autoimmune diabetes in nonobese diabetic (NOD) mice.

P. Bedossa, C. Boitard, J. Bach, 1991, European journal of immunology.

The targeting of β‐cells by T lymphocytes in human type 1 diabetes: clinical perspectives

F. Lemonnier, C. Boitard, C. Briet, 2013, Diabetes, obesity & metabolism.

Role of tap transporter genes in predisposition to insulin dependent diabetes mellitus

C. Boitard, J. Timsit, E. Bertin, 1993 .

Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.

P. Romero, C. Boitard, S. Rome, 2019, Cell metabolism.

Origin of the beta cells of the islets of Langerhans is further questioned by the expression of neuronal intermediate filament proteins, peripherin and NF-L, in the rat insulinoma RIN5F cell line.

F. Gros, C. Boitard, C. Huc, 1991, Developmental neuroscience.

Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice

Batoul Dia, S. Eid, A. Eid, 2019, Diabetes.

Recognition of Human Proinsulin Leader Sequence by Class I–Restricted T-Cells in HLA-A*0201 Transgenic Mice and in Human Type 1 Diabetes

F. Lemonnier, C. Boitard, S. Muller, 2009, Diabetes.

HLA-B7–Restricted Islet Epitopes Are Differentially Recognized in Type 1 Diabetic Children and Adults and Form Weak Peptide-HLA Complexes

S. Buus, G. Bruno, F. Lemonnier, 2012, Diabetes.

Immunology of Diabetes Society T‐Cell Workshop: HLA class I tetramer‐directed epitope validation initiative T‐Cell Workshop Report—HLA Class I Tetramer Validation Initiative

F. Wong, C. Boitard, E. James, 2011, Diabetes/metabolism research and reviews.

Renal hemodynamics and segmental tubular reabsorption in early type 1 diabetes.

C. Boitard, J. Grünfeld, B. Lacour, 1990, Kidney international.

The prevalence of selective IgA deficiency in type 1 diabetes mellitus

C. Boitard, R. Liblau, J. Bach, 1992, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[Emphysematous pyelonephritis in diabetics].

C. Boitard, J. Timsit, C. Pagnoux, 1997, La Revue de medecine interne.

Angiotensin converting enzyme inhibition and chronic cyclosporine-induced renal dysfunction in type 1 diabetes

C. Boitard, J. Grünfeld, B. Lacour, 1996 .

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

MAIT cell alterations in adults with recent-onset and long-term type 1 diabetes

C. Boitard, A. Lehuen, E. Larger, 2021, Diabetologia.

Microglial changes occur without neural cell death in diabetic retinopathy

J. Sahel, P. Massin, S. Picaud, 2007, Vision Research.

Impact of personalized text messages from pharmacists on medication adherence in type 2 diabetes in France: A real-world, randomized, comparative study.

C. Boitard, J. Gautier, Y. Michiels, 2021, Patient education and counseling.

Diagnosing Diabetic Foot Osteomyelitis in PatientsWithout Signs of Soft Tissue Infection by Coupling Hybrid

Benjamin A Lipsky, C. Boitard, E. Larger, 2013 .

Pathophysiology of autoimmune diseases.

C. Boitard, 1990, Klinische Wochenschrift.

Measurement of CD8+ T Cell Responses in Human Type 1 Diabetes

F. Lemonnier, C. Boitard, R. Mallone, 2008, Annals of the New York Academy of Sciences.

In obese and non-obese adults, the cis-regulatory rs361072 promoter variant of PIK3CB is associated with insulin resistance not with type 2 diabetes.

K. Clément, P. Amouyel, J. Ferrières, 2009, Molecular genetics and metabolism.

Humanized Mouse Model to Study Type 1 Diabetes

E. Pasmant, M. Vidaud, F. Lemonnier, 2018, Diabetes.

Evaluation of impaired β‐cell function in nonobese‐diabetic (NOD) mouse model using bioluminescence imaging

C. Aflalo, C. Boitard, D. Melloul, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Shifting the paradigm of islet inflammation—good guy or bad guy?

D. Accili, S. Seino, C. Boitard, 2013, Diabetes, obesity & metabolism.

Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse.

P. Bedossa, C. Boitard, J. Marvel, 1993, International immunology.

CD45RA antibodies split the CD3bright T cell subset.

C. Boitard, J. Marvel, N. Dautigny, 1991, International immunology.

Cell-mediated immunity to pancreatic islet cells in the non-obese diabetic (NOD) mouse: in vitro characterization and time course study.

C. Boitard, J. Timsit, J. Bach, 1988, Clinical and experimental immunology.

A tale of two cousins: type 1 and type 2 diabetes.

D. Steiner, E. Ferrannini, C. Boitard, 2005, Diabetes.

The hyperstimulated β‐cell: prelude to diabetes?

D. Accili, S. Seino, C. Boitard, 2012, Diabetes, obesity & metabolism.

Pancreatic exocrine function in patients with diabetes

C. Boitard, E. Larger, M. Rotariu, 2012, Diabetic medicine : a journal of the British Diabetic Association.

Towards an aetiological treatment of type 1 diabetes? New tools, new strategies.

C. Boitard, J. Timsit, 2012, Diabetes & metabolism.

Icos gene disruption in non‐obese diabetic mice elicits myositis associated with anti‐troponin T3 autoantibodies

G. Riou, C. Boitard, P. Chan, 2023, Neuropathology and applied neurobiology.

What ails the β‐cell?

D. Accili, S. Seino, C. Boitard, 2010, Diabetes, obesity & metabolism.

[Early induction of diabetes in NOD mice by streptozotocin].

S. Orlow, C. Boitard, J. Bach, 1987, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

[Prediction and prevention of type 1 diabetes].

C. Boitard, J. Jos, 1992, Archives francaises de pediatrie.

Tolerance to Proinsulin-2 Is Due to Radioresistant Thymic Cells1

C. Boitard, J. Carel, J. Elliott, 2006, The Journal of Immunology.

Renal abnormalities in normotensive insulin-dependent diabetic offspring of hypertensive parents.

C. Boitard, J. Grünfeld, B. Lacour, 1992, Hypertension.

T-cell regulation in murine and human autoimmune diabetes: the role of TH1 and TH2 cells.

C. Boitard, A. Heurtier, 1997, Diabetes & metabolism.

Transfer of diabetes from prediabetic NOD mice to NOD-SCID/SCID mice: association with pancreatic insulin content.

C. Boitard, E. Larger, M. Füchtenbusch, 2005, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Proinsulin 2 knockout NOD mice: a model for genetic variation of insulin gene expression in type 1 diabetes.

C. Boitard, J. Jami, P. Krief, 2002, Diabetes.

Factors predictive of cyclosporine-induced nephrotoxicity: the role of cyclosporine blood levels.

C. Boitard, J. Timsit, J. Grünfeld, 1990, Transplantation proceedings.

Gene expression signature predicts rate of type 1 diabetes progression

Maria K. Jaakkola, E. Bonifacio, C. de Beaufort, 2023, EBioMedicine.

HLA-associated heterogeneity of the humoral response to islet antigens in insulin-dependent diabetes.

P. van Endert, B. Genetet, C. Boitard, 1995, Journal of autoimmunity.

Prospective external validation of a new non‐invasive test for the diagnosis of non‐alcoholic steatohepatitis in patients with type 2 diabetes

V. Paradis, S. Czernichow, D. Valla, 2021, Alimentary pharmacology & therapeutics.

A Simple and Fast Non-Radioactive Bridging Immunoassay for Insulin Autoantibodies

C. Boitard, N. Morel, C. Créminon, 2013, PloS one.

β‐Cell research – A decade of rapid growth

D. Accili, D. Steiner, S. Seino, 2009, Diabetes, obesity & metabolism.

Long-term complications of conventional immunosuppressive treatment.

C. Boitard, J. Bach, 1989, Advances in nephrology from the Necker Hospital.

High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT, Using a Low Threshold.

V. Paradis, S. Czernichow, D. Valla, 2023, Diabetes care.

[Auto-immune hypoglycemic syndrome induced by pyritinol].

C. Boitard, G. Tchobroutsky, N. Desplanque, 1988, Diabete & metabolisme.

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

K. Owen, C. Boitard, M. Kindermans, 2023, BMC Medicine.

Anti-pancreatic immunity in genetically diabetic mice.

C. Boitard, R. Assan, P. Saï, 1983, Clinical and experimental immunology.

acDCs enhance human antigen-specific T-cell responses.

L. Zitvogel, N. Chaput, C. Boitard, 2011, Blood.

Beyond the hormone: insulin as an autoimmune target in type 1 diabetes.

C. Boitard, R. Mallone, J. Carel, 2011, Endocrine reviews.

Infection of Continuous Subcutaneous Insulin Infusion Site With Mycobacterium peregrinum

C. Boitard, X. Nassif, C. Pagnoux, 1998, Diabetes Care.

Viral infection prevents diabetes by inducing regulatory T cells through NKT cell–plasmacytoid dendritic cell interplay

C. Boitard, M. V. von Herrath, R. Mallone, 2011, The Journal of experimental medicine.

No association between the Friedreich's ataxia gene and NIDDM in the French population.

P. Froguel, C. Boitard, J. Timsit, 1998, Diabetes.

The Spontaneous Autoimmune Neuromyopathy in ICOSL−/− NOD Mice Is CD4+ T-Cell and Interferon-γ Dependent

C. Boitard, C. Arnoult, L. Drouot, 2017, Front. Immunol..

Cyclosporine therapy for severe systemic sclerosis associated with the anti-Scl-70 autoantibody.

C. Boitard, J. Fiessinger, J. Bach, 1990, Journal of the American Academy of Dermatology.

The targeting of β‐cells by T lymphocytes in human type 1 diabetes: clinical perspectives

F. Lemonnier, C. Boitard, C. Briet, 2013, Diabetes, obesity & metabolism.