A. Streets

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Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression.

P. Harris, D. Peters, S. Rossetti, 2017, American journal of physiology. Renal physiology.

The positive effect of selective prostaglandin E2 receptor EP2 and EP4 blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo.

D. Peters, A. Ong, A. Streets, 2020, Kidney international.

Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.

M. O'hare, P. Harris, S. Rossetti, 2007, Kidney international.

Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro.

A. Ong, A. Streets, T. Obara, 2006, Human molecular genetics.

Polycystin-1 regulates ARHGAP35-dependent centrosomal RhoA activation and ROCK signaling

A. Ong, A. Streets, Philipp P. Prosseda, 2020, JCI insight.

Global microRNA profiling in human urinary exosomes reveals novel disease biomarkers and cellular pathways for autosomal dominant polycystic kidney disease.

Y. Pei, A. Streets, T. Magayr, 2020, Kidney international.

Functional Analysis of PKD 1 Transgenic Lines Reveals a Direct Role for Polycystin-1 in Mediating Cell-Cell Adhesion

O. Ibraghimov-Beskrovnaya, M. O'hare, N. Bukanov, 2003 .

Regulation of GLUT1 in response to cellular stress.

S. Baldwin, A. Streets, J. Saklatvala, 1997, Biochemical Society transactions.

Post-translational modifications of the polycystin proteins.

A. Ong, A. Streets, 2020, Cellular signalling.

Protein Kinase D–mediated Phosphorylation of Polycystin-2 (TRPP2) Is Essential for Its Effects on Cell Growth and Calcium Channel Activity

A. Ong, A. Streets, A. Needham, 2010, Molecular biology of the cell.

The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex.

A. Ong, A. Streets, U. Tran, 2017, Journal of the American Society of Nephrology : JASN.

Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion.

O. Ibraghimov-Beskrovnaya, M. O'hare, N. Bukanov, 2003, Journal of the American Society of Nephrology : JASN.

This is a repository copy of Global microRNA profiling in human urinary exosomes reveals novel disease biomarkers and cellular pathways for Autosomal Dominant Polycystic Kidney

Y. Pei, A. Ong, A. Streets, 2021 .

Identiﬁcation of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro

A. Ong, A. Streets, T. Obara, 2006 .

Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells

P. Harris, C. Ward, A. Ong, 2009, Journal of Cell Science.

A sorting nexin 3 retromer regulates the surface localization and activity of a Wnt-activated polycystin channel complex

A. Ong, A. Streets, U. Tran, 2019 .

A high throughput zebrafish chemical screen reveals ALK5 and non-canonical androgen signalling as modulators of the pkd2−/− phenotype

A. Ong, A. Streets, A. Metzner, 2020, Scientific Reports.

Helix pomatia agglutinin lectin‐binding oligosaccharides of aggressive breast cancer

M. Dwek, U. Schumacher, A. Leathem, 2001, International journal of cancer.

A Crucial Sequence for Transglutaminase Type 2 Extracellular Trafficking in Renal Tubular Epithelial Cells Lies in Its N-terminal β-Sandwich Domain

A. Streets, Linghong Huang, T. Johnson, 2011, The Journal of Biological Chemistry.

Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity.

A. Ong, A. Streets, Z. Mao, 2011, American journal of physiology. Renal physiology.

Identification, Characterization, and Localization of a Novel Kidney Polycystin-1-Polycystin-2 Complex*

P. Harris, C. Ward, A. Ong, 2002, The Journal of Biological Chemistry.

The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking.

A. Hounslow, M. Williamson, A. Ong, 2016, Journal of the American Society of Nephrology : JASN.

Identification and Functional Characterization of an N-terminal Oligomerization Domain for Polycystin-2*

A. Ong, A. Streets, L. Tsiokas, 2008, Journal of Biological Chemistry.

A high throughput zebrafish chemical screen reveals ALK5 and non-canonical androgen signalling as modulators of the pkd2−/− phenotype

A. Ong, A. Streets, A. Metzner, 2020, Scientific Reports.

TRPP2 in Polycystic Kidney Disease

A. Ong, A. Streets, 2014 .

The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function*

H. Cantiello, A. Ong, A. Streets, 2015, The Journal of Biological Chemistry.

The cAMP pathway regulates polycystin-2 channel function 1 The cAMP Signaling Pathway and Direct PKA Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function

H. Cantiello, A. Ong, A. Streets, 2015 .

FO026GLOBAL MICRORNA PROFILING IN HUMAN URINARY EXOSOMES REVEALS NEW DISEASE BIOMARKERS AND CELLULAR PATHWAYS FOR AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)

Y. Pei, A. Streets, R. Simms, 2019, Nephrology Dialysis Transplantation.

Activation of TRPP2 through mDia1‐dependent voltage gating

A. Ong, A. Streets, L. Tsiokas, 2008, The EMBO journal.

Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.

D. Peters, A. Ong, A. Streets, 2013, Human molecular genetics.

Identification, purification and analysis of a 55 kDa lectin binding glycoprotein present in breast cancer tissue.

M. Dwek, A. Leathem, A. Streets, 1996, Clinica chimica acta; international journal of clinical chemistry.

The positive effect of selective prostaglandin E2 EP2 and EP4 receptor blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo

A. Streets, M. Valluru, M. Lannoy, 2021 .

The association of urinary epidermal growth factors with ADPKD disease severity and progression

R. Gansevoort, H. van Goor, A. Ong, 2023, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues.

M. Dwek, A. Leathem, A. Streets, 1996, Analytical biochemistry.