A. Keramidas

发表

Investigating the Mechanism by Which Gain-of-function Mutations to the α1 Glycine Receptor Cause Hyperekplexia*

Yan Zhang, A. Bode, Bindi Nguyen, 2016, The Journal of Biological Chemistry.

M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective.

P. H. Barry, P. Schofield, A. Keramidas, 2000, Biophysical journal.

Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1

I. Vetter, R. Lewis, A. Keramidas, 2017, Scientific Reports.

The Free Zinc Concentration in the Synaptic Cleft of Artificial Glycinergic Synapses Rises to At least 1 μM

Yan Zhang, A. Keramidas, J. Lynch, 2016, Front. Mol. Neurosci..

Functional reconstitution of glycinergic synapses incorporating defined glycine receptor subunit combinations

Yan Zhang, A. Keramidas, J. Lynch, 2015, Neuropharmacology.

Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABAA receptors

J. Kelly, A. Keramidas, J. Lynch, 2022, Cell & bioscience.

Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors.

A. Keramidas, J. Lynch, Xiao-Jing Di, 2020, Cell chemical biology.

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors

A. Keramidas, J. Lynch, R. Harvey, 2020, Neurobiology of Disease.

SAHA (Vorinostat) Corrects Inhibitory Synaptic Deficits Caused by Missense Epilepsy Mutations to the GABAA Receptor γ2 Subunit

Nela Durisic, A. Keramidas, J. Lynch, 2018, Front. Mol. Neurosci..

Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

K. Kawakami, M. Suster, A. Bode, 2018, Front. Mol. Neurosci..

Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus

Bindi Nguyen, A. Keramidas, J. Lynch, 2017, PLoS pathogens.

Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP.

Nela Durisic, A. Keramidas, J. Lynch, 2017, ACS chemical biology.

Gain-of-function glycine receptor mutants and hyperekplexia

Yan Zhang, A. Bode, Bindi Nguyen, 2016 .

Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA2− and EGTA3−) for use in electrophysiological experiments

L. Kuhlmann, A. Keramidas, A. Moorhouse, 1999, Journal of Neuroscience Methods.

The effects of insecticides on two splice variants of the glutamate‐gated chloride channel receptor of the major malaria vector, Anopheles gambiae

A. Keramidas, J. Lynch, M. Atif, 2020, British journal of pharmacology.

An outline of desensitization in pentameric ligand-gated ion channel receptors

A. Keramidas, J. Lynch, 2013, Cellular and Molecular Life Sciences.

Anti-seizure mechanisms of midazolam and valproate at the β2(L51M) variant of the GABAA receptor

I. Vetter, A. Keramidas, E. Palmer, 2022, Neuropharmacology.

Identification of Molluscan Nicotinic Acetylcholine Receptor (nAChR) Subunits Involved in Formation of Cation- and Anion-Selective nAChRs

D. Bertrand, A. Smit, A. Keramidas, 2005, The Journal of Neuroscience.

Ligand-gated ion channels: mechanisms underlying ion selectivity.

Peter R Schofield, P. Schofield, A. Keramidas, 2004, Progress in biophysics and molecular biology.

Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

K. Roche, A. Keramidas, J. Lynch, 2021, bioRxiv.

A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition

Yan Zhang, A. Keramidas, J. Lynch, 2020, The Journal of Neuroscience.

Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease

M. Topf, R. Thomas, A. Bode, 2013, Neurobiology of Disease.

Correlating Structural and Energetic Changes in Glycine Receptor Activation*

A. Keramidas, J. Lynch, Suzanne Scott, 2015, The Journal of Biological Chemistry.

GABAA Receptor α and γ Subunits Shape Synaptic Currents via Different Mechanisms*

P. Sah, A. Keramidas, J. Lynch, 2014, The Journal of Biological Chemistry.

New Hyperekplexia Mutations Provide Insight into Glycine Receptor Assembly, Trafficking, and Activation Mechanisms*

E. Karam, H. Mandel, S. Berkovic, 2013, The Journal of Biological Chemistry.

Single Channel Analysis of Conductance and Rectification in Cation-selective, Mutant Glycine Receptor Channels

P. Schofield, A. Keramidas, A. Moorhouse, 2002, The Journal of general physiology.

Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function

Thi Thao Nguyen Ho, Yan Zhang, A. Keramidas, 2017, Front. Mol. Neurosci..

A pain-causing and paralytic ant venom glycopeptide

I. Vetter, R. Payne, A. Keramidas, 2021, iScience.

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

Mehdi Mobli, Glenn F. King, Vi Pham, 2017, Proceedings of the National Academy of Sciences.

Zolpidem and eszopiclone prime α1β2γ2 GABAA receptors for longer duration of activity

N. Harrison, A. Keramidas, J. Lynch, 2015, British journal of pharmacology.

The activation mechanism of α1β2γ2S and α3β3γ2S GABAA receptors

N. Harrison, A. Keramidas, 2010, The Journal of General Physiology.

Taurine Is a Potent Activator of Extrasynaptic GABAA Receptors in the Thalamus

Neil L. Harrison, F. Jia, N. Harrison, 2008, The Journal of Neuroscience.

Inhibitory synapse deficits caused by familial α1 GABAA receptor mutations in epilepsy

Nela Durisic, A. Keramidas, J. Lynch, 2017, Neurobiology of Disease.

Zolpidem and Eszopiclone prime α 1 β 2 γ 2 GABA A receptors for longer duration activity 1

N. Harrison, A. Keramidas, J. Lynch, 2015 .

γ1-Containing GABA-A Receptors Cluster at Synapses Where they Mediate Slower Synaptic Currents than γ2-Containing GABA-A Receptors

P. Sah, Nela Durisic, A. Keramidas, 2017, Front. Mol. Neurosci..

The pre‐M1 segment of the α1 subunit is a transduction element in the activation of the GABAA receptor

N. Harrison, A. Keramidas, ThomasL . Kash, 2006, The Journal of physiology.

GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance

Jennifer J. Smith, A. Keramidas, J. Lynch, 2019, PLoS pathogens.

Cation-selective Mutations in the M2 Domain of the Inhibitory Glycine Receptor Channel Reveal Determinants of Ion-Charge Selectivity

P. Schofield, A. Keramidas, A. Moorhouse, 2002, The Journal of general physiology.

Shisa7-Dependent Regulation of GABAA Receptor Single-Channel Gating Kinetics

D. Castellano, A. Keramidas, Kunwei Wu, 2022, The Journal of Neuroscience.

Agonist-dependent Single Channel Current and Gating in α4β2δ and α1β2γ2S GABAA Receptors

N. Harrison, A. Keramidas, 2008, The Journal of general physiology.

Agonist-dependent Single Channel Current and Gating in (cid:4) 4 (cid:5) 2 (cid:6) and (cid:4) 1 (cid:5) 2 (cid:2) 2S GABA A Receptors

N. Harrison, A. Keramidas, 2008 .

The contribution of proline 250 (P-2′) to pore diameter and ion selectivity in the human glycine receptor channel

P. Schofield, A. Keramidas, A. Moorhouse, 2003, Neuroscience Letters.

Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors

A. Keramidas, J. Lynch, Xiumin Chen, 2017, Neuropharmacology.

Ivermectin-Activated, Cation-Permeable Glycine Receptors for the Chemogenetic Control of Neuronal Excitation.

P. Sah, Nela Durisic, A. Keramidas, 2016, ACS chemical neuroscience.

The activation mechanism of alpha1beta2gamma2S and alpha3beta3gamma2S GABAA receptors.

N. Harrison, A. Keramidas, 2010, The Journal of general physiology.

An outline of desensitization in pentameric ligand-gated ion channel receptors

A. Keramidas, J. Lynch, 2012, Cellular and Molecular Life Sciences.

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

I. Vetter, Nina Brinkwirth, C. Schroeder, 2023, Nature communications.