P. Sacerdote

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Effects of ACL Reconstructive Surgery on Temporal Variations of Cytokine Levels in Synovial Fluid

Alessandra Pedrocchi, Marta Gandolla, A. Pedrocchi, 2016, Mediators of inflammation.

Psychoimmunoendocrine investigation in anorexia nervosa.

F. Petraglia, P. Sacerdote, A. Panerai, 1993, Neuropsychobiology.

Immunoendocrine aspects of anorexia nervosa

P. Sacerdote, A. Panerai, F. Brambilla, 1996, Psychiatry Research.

Prevention and Treatment of Lethal Murine Endotoxemia by the Novel Immunomodulatory Agent MFP-14

F. Nicoletti, K. Mangano, P. Sacerdote, 2001, Antimicrobial Agents and Chemotherapy.

Measurement of Macrophage Toll-Like Receptor 4 Expression After Morphine Treatment.

P. Sacerdote, S. Franchi, A. Panerai, 2020, Methods in molecular biology.

Measurement of macrophage toll-like receptor 4 expression after morphine treatment.

P. Sacerdote, S. Franchi, A. Panerai, 2015, Methods in molecular biology.

Mu opioid receptor activation modulates Toll like receptor 4 in murine macrophages

P. Sacerdote, S. Franchi, A. Panerai, 2012, Brain, Behavior, and Immunity.

Δ9‐Tetrahydrocannabinol‐induced anti‐inflammatory responses in adolescent mice switch to proinflammatory in adulthood

P. Sacerdote, S. Franchi, A. Panerai, 2014, Journal of leukocyte biology.

Benzodiazepines and their antagonists interfere with opioid-dependent stress-induced analgesia

P. Mantegazza, P. Sacerdote, P. Fumagalli, 1990, Pharmacology Biochemistry and Behavior.

Chlorimipramine and nortriptyline but not fluoxetine and fluvoxamine inhibit human polymorphonuclear cell chemotaxis in vitro.

P. Sacerdote, A. Panerai, M. Bianchi, 1994, General pharmacology.

Interleukins and Immunocyte b-Endorphin

P. Sacerdote, 1998 .

Intracerebroventricular interleukin-1 alpha increases immunocyte beta-endorphin concentrations in the rat: involvement of corticotropin-releasing hormone, catecholamines, and serotonin.

P. Sacerdote, A. Panerai, B. Manfredi, 1994, Endocrinology.

Cholecystokinin and the immune system: Receptor-mediated chemotaxis of human and rat monocytes

C. Pert, P. Sacerdote, M. Ruff, 1988, Peptides.

Immunomodulation with Glatiramer Acetate Prevents Long-Term Inflammatory Pain

P. Sacerdote, N. Sharma, G. Pasinetti, 2008, The International journal of neuroscience.

A. Aloisi, G. Carli, M. E. Albonetti, 1995, Brain Research.

Psychological, neuroendocrine and immune measures in non spousal carers of disabled elderly in Italy.

C. Sirolla, M. Melchiorre, G. Lamura, 2004, Neuro endocrinology letters.

Chronic psychosocial stress-induced down-regulation of immunity depends upon individual factors

P. Sacerdote, S. Parmigiani, A. Bartolomucci, 2003, Journal of Neuroimmunology.

Asymmetrical distribution of beta-endorphin in cerebral hemispheres of suicides: Preliminary data

P. Sacerdote, A. Panerai, O. Gambini, 1990, Psychiatry Research.

Frailty and pain, human studies and animal models

P. Sacerdote, S. Franchi, M. Baciarello, 2021, Ageing Research Reviews.

Acute and late changes in intraarticular cytokine levels following anterior cruciate ligament injury

M. Bigoni, M. Turati, Marta Gandolla, 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Peripheral Blood Mononuclear Cell &bgr;-Endorphin Concentration Is Decreased in Chronic Fatigue Syndrome and Fibromyalgia but Not in Depression: Preliminary Report

P. Sacerdote, P. Meroni, A. Panerai, 2002, The Clinical journal of pain.

β-Endorphin levels in peripheral blood mononuclear cells and long-term naltrexone treatment in autistic children

P. Sacerdote, A. Panerai, A. G. Cazzullo, 1999, European Neuropsychopharmacology.

Beta-endorphin and cholecystokinin 8 concentrations in peripheral blood mononuclear cells of autistic children.

P. Sacerdote, A. Panerai, F. Brambilla, 1997, Neuropsychobiology.

β-Endorphin content in HIV-infected HuT78 cell line and in peripheral lymphocytes from HIV-positive subjects

A. Lazzarin, P. Sacerdote, P. Meroni, 1994, Peptides.

Psychoimmunoendocrine aspects of panic disorder.

F. Petraglia, P. Sacerdote, L. Bellodi, 1992, Neuropsychobiology.

Plasma and synovial fluid interleukin-1, interleukin-6 and substance P concentrations in rheumatoid arthritis patients: Effect of the nonsteroidal anti inflammatory drugs indomethacin, diclofenac and naproxen

P. Sacerdote, A. Panerai, B. Manfredi, 1995, Inflammation Research.

Effects of the bisphosphonate ibandronate on hyperalgesia, substance P, and cytokine levels in a rat model of persistent inflammatory pain

M. L. Sotgiu, P. Sacerdote, S. Franchi, 2008, European journal of pain.

Non-analgesic effects of opioids: mechanisms and potential clinical relevance of opioid-induced immunodepression.

P. Sacerdote, S. Franchi, A. Panerai, 2012, Current pharmaceutical design.

Effects of tramadol on synovial fluid concentrations of substance P and interleukin-6 in patients with knee osteoarthritis: comparison with paracetamol.

P. Sacerdote, A. Panerai, P. Ferrario, 2003, International immunopharmacology.

Intra-Articular Cytokine Levels in Adolescent Patients after Anterior Cruciate Ligament Tear

A. Pedrocchi, M. Bigoni, M. Turati, 2018, Mediators of inflammation.

Prokineticin Receptor Inhibition With PC1 Protects Mouse Primary Sensory Neurons From Neurotoxic Effects of Chemotherapeutic Drugs in vitro

P. Sacerdote, S. Franchi, M. Kress, 2020, Frontiers in Immunology.

Presence of a reduced opioid response in interleukin‐6 knock out mice

G. Ciliberto, P. Sacerdote, T. Rubino, 1999, The European journal of neuroscience.

IL-6 Knock-Out Mice Show Modified Basal Immune Functions, but Normal Immune Responses to Stress

V. Poli, P. Sacerdote, A. Panerai, 1998, Brain, Behavior, and Immunity.

Do All Opioid Drugs Share the Same Immunomodulatory Properties? A Review From Animal and Human Studies

P. Sacerdote, S. Franchi, G. Amodeo, 2019, Front. Immunol..

T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa

P. Sacerdote, G. Perna, A. Panerai, 1995, Psychiatry Research.

Plasma interleukin-1 beta concentrations in panic disorder

P. Sacerdote, L. Bellodi, G. Perna, 1994, Psychiatry Research.

Changes of Substance P in the Crevicular Fluid in relation to Orthodontic Movement Preliminary Investigation

P. Sacerdote, A. Caprioglio, L. Levrini, 2013, TheScientificWorldJournal.

Genistein, a natural phytoestrogen from soy, relieves neuropathic pain following chronic constriction sciatic nerve injury in mice: anti‐inflammatory and antioxidant activity

P. Sacerdote, S. Franchi, A. Panerai, 2008, Journal of neurochemistry.

Hypothalamic β‐Endorphin Concentrations Are Decreased in Animal Models of Autoimmune Disease

P. Sacerdote, A. Panerai, O. Lechner, 1999, Annals of the New York Academy of Sciences.

Hypothalamic β-endorphin concentrations are decreased in animals models of autoimmune disease

P. Sacerdote, A. Panerai, O. Lechner, 1999, Journal of Neuroimmunology.

In vivo and in vitro treatment with the synthetic cannabinoid CP55,940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors

P. Sacerdote, P. Massi, D. Parolaro, 2000, Journal of Neuroimmunology.

Differential involvement of RelB in morphine‐induced modulation of chemotaxis, NO, and cytokine production in murine macrophages and lymphocytes

P. Sacerdote, S. Franchi, A. Panerai, 2007, Journal of leukocyte biology.

Modulation of experimental allergic encephalomyelitis in Lewis rats by administration of a peptide of Fas ligand.

B. Pollo, P. Sacerdote, A. Salmaggi, 2001, Journal of autoimmunity.

myc‐Immortalized Microglial Cells Express a Functional Platelet‐Activating Factor Receptor

P. Sacerdote, M. Righi, F. Marangoni, 1995, Journal of neurochemistry.

Systemic administration of human adipose-derived stem cells reverts nociceptive hypersensitivity in an experimental model of neuropathy.

P. Sacerdote, S. Franchi, A. Rossi, 2013, Stem cells and development.

Chronic Administration of UK‐114, a Multifunctional Emerging Protein, Modulates the Th1/Th2 Cytokine Pattern and Experimental Autoimmune Diseases

F. Nicoletti, P. Sacerdote, F. Ceciliani, 1999, Annals of the New York Academy of Sciences.

Beta-endorphin in the immune system: a role at last?

P. Sacerdote, A. Panerai, 1997, Immunology today.

Immune function alterations in mice tolerant to Δ9-tetrahydrocannabinol: functional and biochemical parameters

P. Sacerdote, P. Massi, T. Rubino, 1998, Journal of Neuroimmunology.

Effects of tramadol and its enantiomers on Concanavalin-A induced-proliferation and NK activity of mouse splenocytes: involvement of serotonin.

P. Sacerdote, A. Panerai, M. Bianchi, 1999, International journal of immunopharmacology.

Effects of tramadol on immune responses and nociceptive thresholds in mice

P. Sacerdote, A. Panerai, B. Manfredi, 1997, Pain.

Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals

L. Rodella, P. Sacerdote, G. Balboni, 2014, British journal of pharmacology.

Antidepressants in Cancer Pain

F. De Conno, P. Sacerdote, A. Panerai, 1991, Journal of palliative care.

Secretome of human adipose-derived mesenchymal stem cell relieves pain and neuroinflammation independently of the route of administration in experimental osteoarthritis

P. Sacerdote, S. Franchi, A. Brini, 2021, Brain, Behavior, and Immunity.

Intermittent but not continuous inescapable footshock stress and intracerebroventricular interleukin-1 similarly affect immune responses and immunocyte beta-endorphin concentrations in the rat.

P. Sacerdote, A. Panerai, B. Manfredi, 1997, International journal of clinical pharmacology research.

Intermittent but Not Continuous Inescapable Footshock Stress Affects Immune Responses and Immunocyte Beta-Endorphin Concentrations in the Rat

P. Sacerdote, A. Panerai, B. Manfredi, 1994, Brain, Behavior, and Immunity.

Biological components in a standardized derivative of bovine colostrum.

P. Sacerdote, S. Franchi, B. Bussolati, 2013, Journal of dairy science.

The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

P. Sacerdote, S. Franchi, A. Panerai, 2008, BMC Immunology.

Antinociceptive and immunosuppressive effects of opiate drugs: a structure‐related activity study

P. Mantegazza, P. Sacerdote, A. Panerai, 1997, British journal of pharmacology.

Carbamazepine exerts anti-inflammatory effects in the rat.

P. Sacerdote, A. Panerai, G. Rossoni, 1995, European journal of pharmacology.

Bv8, the amphibian homologue of the mammalian prokineticins, induces a proinflammatory phenotype of mouse macrophages

P. Sacerdote, S. Franchi, H. Tian, 2006, British journal of pharmacology.

Cloned microglial cells but not macrophages synthesize β‐endorphin in response to CRH activation

P. Ricciardi-Castagnoli, F. Granucci, P. Sacerdote, 1993, Glia.

The Effects of Tramadol and Morphine on Immune Responses and Pain After Surgery in Cancer Patients

M. Ammatuna, P. Sacerdote, A. Panerai, 2000, Anesthesia and analgesia.

Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

P. Sacerdote, S. Franchi, C. Gotti, 2016, PloS one.

Human monocyte chemotactic activity of calcitonin and somatostatin related peptides: modulation by chronic peptide treatment.

P. Sacerdote, A. Panerai, M. Bianchi, 1990, The Journal of clinical endocrinology and metabolism.

Effects of NSAIDs and paracetamol (acetaminophen) on protein kinase C epsilon translocation and on substance P synthesis and release in cultured sensory neurons

V. Vellani, P. Sacerdote, S. Franchi, 2013, Journal of pain research.

The soy isoflavone genistein reverses oxidative and inflammatory state, neuropathic pain, neurotrophic and vasculature deficits in diabetes mouse model.

P. Sacerdote, S. Franchi, A. Rossi, 2011, European journal of pharmacology.

Cytokines and Cognitive Function in Mice

P. Sacerdote, A. Panerai, M. Bianchi, 1998, Neurosignals.

Perspectives in Pain Research 2014: Neuroinflammation and glial cell activation: The cause of transition from acute to chronic pain?

L. Arendt-Nielsen, P. Sacerdote, B. Cairns, 2015, Scandinavian journal of pain.

T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa

P. Sacerdote, A. Panerai, F. Brambilla, 1995, Psychiatry Research.

Oxotremorine-induced modifications of the behavioral and neuroendocrine responses to formalin pain in male rats

A. Aloisi, G. Carli, P. Sacerdote, 1999, Brain Research.

Regulation of immune functions in rat splenocytes after acute and chronic in vivo treatment with CP-55,940, a synthetic cannabinoid compound

P. Sacerdote, D. Parolaro, B. Manfredi, 1997, Journal of Neuroimmunology.

Drug Use in Special Populations

P. Sacerdote, 2009 .

Osteoarthritis Pain in Old Mice Aggravates Neuroinflammation and Frailty: The Positive Effect of Morphine Treatment

P. Sacerdote, S. Franchi, M. Baciarello, 2022, Biomedicines.

Effect of ibuprofen and diclofenac on the chemotaxis induced by substance P and transforming growth factor-beta on human monocytes and polymorphonuclear cells.

P. Mantegazza, P. Sacerdote, A. Panerai, 1993, International journal of immunopharmacology.

Brain and spinal cord neuropeptides in adjuvant induced arthritis in rats.

P. Mantegazza, P. Sacerdote, A. Panerai, 1987, Life sciences.

Tritiated D‐ala1‐peptide T binding: A pharmacologic basis for the design of drugs which inhibit HIV receptor binding

C. Pert, B. Martin, P. Sacerdote, 1988 .

Benzodiazepine induced chemotaxis of human monocytes: a tool for the study of benzodiazepine receptors.

P. Sacerdote, A. Panerai, L. Locatelli, 1993, Life sciences.

β-Endorphin concentrations in brain areas and peritoneal macrophages in rats susceptible and resistant to experimental allergic encephalomyelitis: A possible relationship between tumor necrosis factor α and opioids in the disease

P. Sacerdote, J. Radulovic, A. Panerai, 1994, Journal of Neuroimmunology.

T-lymphocyte proliferative response to mitogen stimulation in elderly depressed patients.

P. Sacerdote, F. Brambilla, T. Cenacchi, 1995, Journal of affective disorders.

Beta-Endorphin Levels are Reduced in Peripheral Blood Mononuclear Cells of Cluster Headache Patients

P. Sacerdote, A. Panerai, M. Leone, 1993, Cephalalgia : an international journal of headache.

Beta-Endorphin Concentrations in the Peripheral Blood Mononuclear Cells of Migraine and Tension-Type Headache Patients

P. Sacerdote, A. Panerai, M. Leone, 1992, Cephalalgia : an international journal of headache.

Immune cell-derived opioid peptides: Back to the future

P. Sacerdote, 2007, Brain, Behavior, and Immunity.

ϰ-Receptor antagonist reverse ‘non-opioid’ stress-induced analgesia

P. Mantegazza, P. Sacerdote, A. Panerai, 1984, Brain Research.

Vasoactive intestinal peptide 1‐12: A ligand for the CD4 (T4)/human immunodeficiency virus receptor

C. Pert, P. Sacerdote, M. Ruff, 1987, Journal of neuroscience research.

Characterization of synovial fluid cytokine profiles in chronic meniscal tear of the knee

A. Pedrocchi, M. Bigoni, M. Turati, 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Effects of in Vitro and in Vivo Opioids on the Production of IL‐12 and IL‐10 by Murine Macrophages

P. Sacerdote, 2003, Annals of the New York Academy of Sciences.

Differential morphine tolerance development in the modulation of macrophage cytokine production in mice

P. Sacerdote, A. Panerai, L. Gaspani, 2002, Journal of leukocyte biology.

VIP1–12 Is a Ligand for the CD4/Human Immunodeficiency Virus Receptor

C. Pert, P. Sacerdote, M. Ruff, 1988, Annals of the New York Academy of Sciences.

Opioid-induced immunosuppression

P. Sacerdote, 2008, Current opinion in supportive and palliative care.

E. Clementi, P. Sacerdote, A. Panerai, 1995, Peptides.

Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone)

A. Dahan, P. Sacerdote, G. Hans, 2008, Pain practice : the official journal of World Institute of Pain.

Buprenorphine and methadone maintenance treatment of heroin addicts preserves immune function

P. Sacerdote, S. Franchi, A. Panerai, 2008, Brain, Behavior, and Immunity.

Buprenorphine ameliorates the effect of surgery on hypothalamus–pituitary–adrenal axis, natural killer cell activity and metastatic colonization in rats in comparison with morphine or fentanyl treatment

P. Sacerdote, S. Franchi, A. Panerai, 2007, Brain, Behavior, and Immunity.

Effectiveness of electroacupuncture analgesia compared with opioid administration in a dog model: a pilot study.

P. Sacerdote, V. Bronzo, G. Ravasio, 2011, British journal of anaesthesia.

Visualization of cholecystokinin receptors on a subset of human monocytes and in rat spleen

C. Pert, P. Sacerdote, L. Wahl, 1991, Peptides.

Antiepileptic Agents Affect Hypothalamic β‐Endorphin Concentrations

P. Mantegazza, P. Sacerdote, A. Panerai, 1984 .

Current Knowledge of Buprenorphine and Its Unique Pharmacological Profile

Albert Dahan, Richard Langford, Sebastiano Mercadante, 2010, Pain practice : the official journal of World Institute of Pain.

Opioids and the immune system

P. Sacerdote, 2006, Palliative medicine.

Use of human Adipose-derived Stem Cells in a mouse model of neuropathic pain

P. Sacerdote, S. Franchi, A. Rossi, 2011 .

Beta-endorphin concentration in peripheral blood mononuclear cells of elderly depressed patients--effects of phosphatidylserine therapy.

P. Sacerdote, A. Panerai, F. Brambilla, 1996, Neuropsychobiology.

Topical treatment of radiation-induced dermatitis: current issues and potential solutions

P. Sacerdote, Y. Torrente, L. Giacomelli, 2020, Drugs in context.

Nimesulide inhibits protein kinase C epsilon and substance P in sensory neurons – comparison with paracetamol

V. Vellani, P. Sacerdote, S. Franchi, 2011, Journal of pain research.

Increased Tumor Necrosis Factor-α and Prostaglandin E2 Concentrations in the Cerebrospinal Fluid of Rats with Inflammatory Hyperalgesia: The Effects of Analgesic Drugs

P. Sacerdote, S. Franchi, P. Ferrario, 2007, Anesthesia and analgesia.

Cognitive function in young and adult IL (interleukin)-6 deficient mice

A. Aloisi, P. Sacerdote, A. Panerai, 2004, Behavioural Brain Research.

Effects of nimesulide on pain and on synovial fluid concentrations of substance P, interleukin‐6 and interleukin‐8 in patients with knee osteoarthritis: comparison with celecoxib

P. Sacerdote, S. Franchi, M. Bianchi, 2007, International journal of clinical practice.

Dissociation of tolerance and dependence to morphine: a possible role for cholecystokinin

P. Mantegazza, P. Sacerdote, A. Panerai, 1987, Brain Research.

Behavioral and physiological characterization of male mice under chronic psychosocial stress

P. Sacerdote, S. Parmigiani, A. Bartolomucci, 2004, Psychoneuroendocrinology.

Diclofenac Increases Beta-Endorphin Plasma Concentrations

P. Sacerdote, A. Panerai, G. Picotti, 1984, The Journal of international medical research.

Lymphocyte cholecystokinin concentrations in panic disorder.

P. Sacerdote, L. Bellodi, A. Panerai, 1993, The American journal of psychiatry.

P. Sacerdote, P. Meroni, A. Panerai, 1991, Peptides.

Effects of Proglumide on Morphine Analgesia and Tolerance a

P. Sacerdote, A. Panerai, L. Rovati, 1985 .

Central effects of tumor necrosis factor α and interleukin-1α on nociceptive thresholds and spontaneous locomotor activity

P. Ricciardi-Castagnoli, P. Mantegazza, P. Sacerdote, 1992, Neuroscience Letters.

Tumor Necrosis Factor Alpha and Interleukin‐1 Alpha Increase Pain Thresholds in the Rat

P. Ricciardi-Castagnoli, P. Sacerdote, A. Panerai, 1992, Annals of the New York Academy of Sciences.

Corticotropin releasing hormone, interleukin-1α, and tumor necrosis factor-α share characteristics of stress mediators

P. Mantegazza, P. Sacerdote, A. Panerai, 1991, Brain Research.

Autotomy and central nervous system neuropeptides after section of the sciatic nerve in rats of different strains

P. Mantegazza, P. Sacerdote, A. Panerai, 1987, Pharmacology Biochemistry and Behavior.

A role for serotonin and beta-endorphin in the analgesia induced by some tricyclic antidepressant drugs

P. Mantegazza, P. Sacerdote, A. Panerai, 1987, Pharmacology Biochemistry and Behavior.

Peripherally administered GM-CSF interferes with scopolamine-induced amnesia in mice: involvement of interleukin-1

P. Sacerdote, A. Panerai, M. Bianchi, 1996, Brain Research.

Studies on the effects of antidepressant drugs on the antinociceptive action of morphine and on plasma morphine in rat and man

E. Zecca, P. Sacerdote, A. Panerai, 1990, Pain.

Social factors and individual vulnerability to chronic stress exposure

R. Dantzer, A. Sgoifo, P. Sacerdote, 2005, Neuroscience & Biobehavioral Reviews.

A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis

M. Cursi, V. Martinelli, G. Comi, 2008, Multiple sclerosis.

The VGF-derived peptide TLQP-21: A new modulatory peptide for inflammatory pain

M. Ciotti, P. Sacerdote, A. Moles, 2008, Neuroscience Letters.

Panax ginseng C.A. Mayer G115 modulates pro-inflammatory cytokine production in mice throughout the increase of macrophage toll-like receptor 4 expression during physical stress

P. Sacerdote, F. Scaglione, V. Lucini, 2006, Brain, Behavior, and Immunity.

Evidence for an opioid inhibitory effect on T cell proliferation

P. Sacerdote, A. Panerai, B. Manfredi, 1993, Journal of Neuroimmunology.

Experimental evidence for immunomodulatory effects of opioids.

P. Sacerdote, L. Gaspani, Elena Limiroli, 2003, Advances in experimental medicine and biology.

The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1β, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice

L. Rodella, P. Sacerdote, S. Franchi, 2008, PAIN®.

Mainly mu-opiate receptors are involved in luteinizing hormone and prolactin secretion.

F. Petraglia, A. Genazzani, P. Sacerdote, 1985, Endocrinology.

Benzodiazepine-induced chemotaxis is impaired in monocytes from patients with generalized anxiety disorder

P. Sacerdote, A. Panerai, C. Ferrarese, 1999, Psychoneuroendocrinology.

Analysis of the beta-endorphin structure-related activity on human monocyte chemotaxis: Importance of the N- and C-terminal

P. Sacerdote, A. Panerai, 1989, Peptides.

13-end0rphin in the immune system: a r01e at last?

P. Sacerdote, A. Panerai, 1997 .

Mononuclear cell beta-endorphin concentration in women with and without endometriosis.

P. Vercellini, P. Sacerdote, A. Panerai, 1992, Obstetrics and gynecology.

The β-endorphin inhibition of mitogen-induced splenocytes proliferation is mediated by central and peripheral paracrine/autocrine effects of the opioid

F. Granucci, P. Sacerdote, A. Panerai, 1995, Journal of Neuroimmunology.

Peripheral Mechanisms of Dental Pain: The Role of Substance P

Luca Levrini, P. Sacerdote, Paola Sacerdote, 2012, Mediators of inflammation.

Preliminary study on the effect of size of individual stall on the behavioural and immune reactions of dairy calves

P. Sacerdote, A. Panerai, E. Canali, 1998 .

Effect of chronic morphine on plasma and brain beta endorphin and methionine enkephalin in pregnant rats and in their fetuses or newborn.

P. Sacerdote, A. Panerai, A. Marini, 1988, Neuroendocrinology.

Chronic fentanyl or buprenorphine infusion in the mouse: similar analgesic profile but different effects on immune responses

P. Sacerdote, A. Panerai, C. Martucci, 2004, Pain.

Opioids and immune system

P. Sacerdote, S. Franchi, 2006, Palliative medicine.

Effect of Tapentadol on Splenic Cytokine Production in Mice

Marta Gandolla, P. Sacerdote, S. Franchi, 2017, Anesthesia and analgesia.

The opioid antagonist naloxone induces a shift from type 2 to type 1 cytokine pattern in BALB/cJ mice.

P. Sacerdote, A. Panerai, B. Manfredi, 2000, Blood.

Sublingual sufentanil, a new opportunity for the improvement of postoperative pain management in Italy.

P. Sacerdote, F. Coluzzi, A. Fanelli, 2016, European review for medical and pharmacological sciences.

Adult Stem Cell as New Advanced Therapy for Experimental Neuropathic Pain Treatment

A. Vescovi, P. Sacerdote, S. Franchi, 2014, BioMed research international.

Cytokine Modulation is Necessary for Efficacious Treatment of Experimental Neuropathic Pain

P. Sacerdote, S. Franchi, A. Panerai, 2013, Journal of Neuroimmune Pharmacology.

Intravenous neural stem cells abolish nociceptive hypersensitivity and trigger nerve regeneration in experimental neuropathy

A. Vescovi, L. Rodella, P. Sacerdote, 2012, PAIN®.

The Opioid Antagonist Naloxone Induces a Shift from Type 2 to Type 1 Cytokine Pattern in Normal and Skin‐Grafted Mice

P. Sacerdote, A. Panerai, L. Gaspani, 2000, Annals of the New York Academy of Sciences.

Immune function after major surgical interventions: the effect of postoperative pain treatment

P. Sacerdote, S. Franchi, M. Allegri, 2018, Journal of pain research.

The analgesic drug tramadol prevents the effect of surgery on natural killer cell activity and metastatic colonization in rats

P. Sacerdote, A. Panerai, M. Bianchi, 2002, Journal of Neuroimmunology.

Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview.

P. Sacerdote, M. Barbagallo, 2018, Minerva pediatrica.

Effects of tramadol on experimental inflammation

P. Sacerdote, A. Panerai, G. Rossoni, 1999, Fundamental & clinical pharmacology.

Brain and gut neuropeptides in peripheral blood mononuclear cells

P. Sacerdote, A. Panerai, 1993, Journal of Physiology-Paris.

High amounts of beta-endorphin in peripheral blood mononuclear cells from HANE patients.

P. Sacerdote, R. Perricone, A. Panerai, 1991, Immunopharmacology.

Murine models of human neuropathic pain.

P. Sacerdote, M. Colleoni, 2010, Biochimica et biophysica acta.

Panax ginseng C.A. Mayer G115 modulates pro-inflammatory cytokine production in mice throughout the increase of macrophage toll-like receptor 4 expression during physical stress

P. Sacerdote, F. Scaglione, V. Lucini, 2006, Brain, Behavior, and Immunity.

Exposure of Adolescent Mice to Delta-9-Tetrahydrocannabinol Induces Long-Lasting Modulation of Pro- and Anti-Inflammatory Cytokines in Hypothalamus and Hippocampus Similar to that Observed for Peripheral Macrophages

P. Sacerdote, S. Franchi, A. Panerai, 2015, Journal of Neuroimmune Pharmacology.

Pain in Women: A Perspective Review on a Relevant Clinical Issue that Deserves Prioritization

P. Sacerdote, C. Tassorelli, R. Casale, 2021, Pain and Therapy.

Tumor necrosis factor alpha differentially regulates beta-endorphin concentrations and proopiomelanocortin RNA in the anterior and neurointermediate pituitary in vivo.

P. Sacerdote, J. Radulovic, A. Panerai, 1994, Neuroimmunomodulation.

Naloxone-reversible and non-reversible shock-induced analgesia during development

P. Mantegazza, P. Sacerdote, A. Panerai, 1985, Neuroscience Letters.

Plasma levels of b-endorphin and in vitro lymphocyte proliferation as indicator of welfare in horses in normal or restrained conditions

P. Sacerdote, A. Panerai, E. Canali, 1996 .

The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

I. Screpanti, S. Salvadori, P. Sacerdote, 2009, Proceedings of the National Academy of Sciences.

P. Sacerdote, S. Franchi, A. Panerai, 2015, Journal of Neuroimmune Pharmacology.

Diclofenac and pirprofen modify pituitary and hypothalamic beta-endorphin concentrations.

P. Mantegazza, P. Sacerdote, A. Panerai, 1985, Pharmacological research communications.

Transient early expression of TNF-α in sciatic nerve and dorsal root ganglia in a mouse model of painful peripheral neuropathy

P. Sacerdote, S. Franchi, A. Panerai, 2008, Neuroscience Letters.

Experimentally Induced Pulpal Lesion and Substance P Expression: Effect of Ketoprofen—A Preliminary Study

P. Sacerdote, A. Mangano, L. Levrini, 2016, International journal of dentistry.

Interplay between Prokineticins and Histone Demethylase KDM6A in a Murine Model of Bortezomib-Induced Neuropathy

P. Sacerdote, S. Franchi, F. Caputi, 2021, International journal of molecular sciences.

Controlling the activation of the prokineticin system as therapeutic approach to relief neuropathic pain and reduce neuroinflammation

P. Sacerdote, S. Franchi, G. Galimberti, 2022, Pharmadvances.

Prokineticin 2 promotes and sustains neuroinflammation in vincristine treated mice: Focus on pain and emotional like behavior

P. Sacerdote, S. Franchi, G. Balboni, 2019, Brain, Behavior, and Immunity.

Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy

P. Sacerdote, S. Franchi, G. Balboni, 2019, Journal of Neuroinflammation.

The prokineticin system: an interface between neural inflammation and pain

P. Sacerdote, S. Franchi, A. Panerai, 2017, Neurological Sciences.

The Antagonism of the Prokineticin System Counteracts Bortezomib Induced Side Effects: Focus on Mood Alterations

P. Sacerdote, S. Franchi, G. Balboni, 2021, International journal of molecular sciences.

Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

L. Rodella, S. Salvadori, P. Sacerdote, 2015, BioMed research international.

Pharmacological activity of a Bv8 analogue modified in position 24

D. Barra, P. Sacerdote, S. Franchi, 2012, British journal of pharmacology.

Therapeutic effect of human adipose-derived stem cells and their secretome in experimental diabetic pain

L. Rodella, P. Sacerdote, S. Franchi, 2017, Scientific Reports.

Substance P expression in the gingival tissue after upper third molar extraction: effect of ketoprofen, a preliminary study.

P. Sacerdote, A. Mangano, L. Levrini, 2017, Journal of biological regulators and homeostatic agents.

Characterization of Synovial Cytokine Patterns in Bucket-Handle and Posterior Horn Meniscal Tears

A. Pedrocchi, M. Bigoni, M. Turati, 2020, Mediators of inflammation.

Effect of the opioid remifentanil on cellular immune response in the rat.

P. Sacerdote, A. Panerai, G. Rossoni, 2001, International immunopharmacology.

sclerosisdifferent clinical phenotypes of multiple ß endorphin concentrations in PBMC of patients

M. Rovaris, M. Filippi, G. Comi, 2005 .

β endorphin concentrations in PBMC of patients with different clinical phenotypes of multiple sclerosis

M. Rovaris, M. Filippi, G. Comi, 2003, Journal of neurology, neurosurgery, and psychiatry.

PPADS, a purinergic antagonist reduces Fos expression at spinal cord level in a mouse model of mononeuropathy

L. Rodella, R. Rezzani, P. Sacerdote, 2008, Brain Research.

Central effects of tumor necrosis factor alpha and interleukin-1 alpha on nociceptive thresholds and spontaneous locomotor activity.

P. Ricciardi-Castagnoli, P. Mantegazza, P. Sacerdote, 1992, Neuroscience letters.

Neuropeptide Receptors Are Shared Components of Nervous and Immune Systems

C. Pert, P. Sacerdote, C. Wiedermann, 1989 .

Analgesic effects of μ antagonists after naloxone non-reversible stress-induced analgesia

P. Mantegazza, P. Sacerdote, A. Panerai, 1985, Brain Research.

Catecholamine and serotonin depletion from rat spinal cord: effects on morphine and footshock induced analgesia.

P. Sacerdote, E. Nisoli, A. Panerai, 1992, Pharmacological research.

Chronic intrathecal cannulation affects hypothalamic opioids depending on the technique employed

P. Sacerdote, A. Panerai, B. Dib, 1991, Pharmacology Biochemistry and Behavior.

Resolvin E1 and Cytokines Environment in Skeletally Immature and Adult ACL Tears

A. Pedrocchi, M. Bigoni, M. Turati, 2021, Frontiers in Medicine.

Chronic intrathecal cannulation affects hypothalamic beta-endorphin and met-enkephalin concentrations.

P. Sacerdote, A. Panerai, L. Rovati, 1988, Journal of Pharmacological Methods.

Effects of long-term exposure of lemon essential oil odor on behavioral, hormonal and neuronal parameters in male and female rats

A. Aloisi, P. Sacerdote, I. Ceccarelli, 2004, Brain Research.

Effects of chlomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat

P. Sacerdote, A. Panerai, G. Rossoni, 1995, Inflammation Research.

Fluoxetine reduces inflammatory edema in the rat: involvement of the pituitary-adrenal axis.

P. Sacerdote, A. Panerai, M. Bianchi, 1994, European journal of pharmacology.

Role of beta-endorphin in the modulation of immune responses: perspectives in autoimmune diseases.

P. Sacerdote, A. Panerai, L. Gaspani, 2001, Advances in Experimental Medicine and Biology.

Inhibin and activin modulate human monocyte chemotaxis and human lymphocyte interferon-gamma production.

C. Franceschi, F. Petraglia, P. Sacerdote, 1991, The Journal of clinical endocrinology and metabolism.

Neuroendocrine and Behavioral Effects of CRH Blockade and Stress in Male Rats

A. Aloisi, P. Sacerdote, C. Lupo, 1999, Physiology & Behavior.

Involvement of β-endorphin in the modulation of paw inflammatory edema in the rat

P. Sacerdote, A. Panerai, M. Bianchi, 1996, Regulatory Peptides.

Pharmacological modulation of neuropeptides in peripheral mononuclear cells

P. Mantegazza, P. Sacerdote, A. Panerai, 1991, Journal of Neuroimmunology.

Veralipride for hot flushes induced by a gonadotropin-releasing hormone agonist: a controlled study.

P. Vercellini, P. Crosignani, P. Sacerdote, 1994, Fertility and Sterility.

Beta‐Endorphin Concentrations in Resting Peripheral Mononuclear Cells and after Treatment with PHA or Serotoninergic Drugs in Human Aging, Alzheimer's Disease, and Down's Syndrome

P. Sacerdote, A. Panerai, B. Manfredi, 1992, Annals of the New York Academy of Sciences.

Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy

P. Sacerdote, S. Franchi, G. Balboni, 2019, Journal of Neuroinflammation.

Beta-Endorphin in Peripheral Blood Mononuclear Cells: Effect of Aging and Pharmacological Treatments

E. Clementi, P. Sacerdote, A. Panerai, 1994 .

Layer- and subregion-specific electrophysiological and morphological changes of the medial prefrontal cortex in a mouse model of neuropathic pain

M. Mitrić, F. Ferraguti, P. Sacerdote, 2019, Scientific Reports.

Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood

C. Franceschi, P. Sacerdote, D. Monti, 2003, Psychiatry Research.

Beta‐endorphin, vasoactive intestinal peptide and cholecystokinin in peripheral blood mononuclear cells from healthy subjects and from drug‐free and haloperidol‐treated schizophrenic patients

P. Sacerdote, A. Panerai, E. Monzani, 1992, Acta psychiatrica Scandinavica.

Treatment of chronic pain in Italy: therapeutic appropriacy of opioids and fear of addiction: the situation in Italy vs. USA

A. Mugelli, P. Sacerdote, D. Parolaro, 2020 .

P. Sacerdote, A. Panerai, B. Manfredi, 1991, Annals of the New York Academy of Sciences.

Chlomipramine differently affects inflammatory edema and pain in the rat

P. Sacerdote, A. Panerai, M. Bianchi, 1994, Pharmacology Biochemistry and Behavior.

In vivo and in vitro clomipramine treatment decreases the migration of macrophages in the rat.

P. Sacerdote, A. Panerai, M. Bianchi, 1997, European journal of pharmacology.

Cholecystokinin, β-endorphin and vasoactive intestinal peptide in peripheral blood mononuclear cells of drug-naive schizophrenic patients treated with haloperidol compared to healthy controls

P. Sacerdote, A. Panerai, M. Mauri, 1998, Psychiatry Research.

Lornoxicam inhibits human polimorphonuclear cell migration induced by fMLP, interleukin-8 and Substance P

P. Sacerdote, M. Bianchi, 2005 .

Characterization of prokineticin system in Crohn's disease pathophysiology and pain, and its modulation by alcohol abuse: A preclinical study

P. Sacerdote, S. Franchi, G. Amodeo, 2023, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

Effect of Psychoactive Drugs on Lymphocyte Neuropeptides

P. Sacerdote, A. Panerai, I. Ciciliato, 1990, Annals of the New York Academy of Sciences.

Immune aspects in elderly depression: peripheral blood mononuclear cell responses to mitogen stimulation and cytokine plasma concentrations

P. Sacerdote, F. Brambilla, A. Panerai, 1997, Aging.

Opioids in Immune Cells

P. Sacerdote, A. Panerai, I. Ciciliato, 1991 .

Evaluation of murine macrophage cytokine production after in vivo morphine treatment.

P. Sacerdote, S. Franchi, A. Panerai, 2015, Methods in molecular biology.

Central nervous system neuropeptides after peripheral nerve deafferentation

P. Mantegazza, P. Sacerdote, A. Panerai, 1988, Peptides.

The nonpsychoactive component of marijuana cannabidiol modulates chemotaxis and IL-10 and IL-12 production of murine macrophages both in vivo and in vitro

P. Sacerdote, P. Massi, D. Parolaro, 2005, Journal of Neuroimmunology.

Prokineticin 2 and Cytokine Content in the Synovial Fluid of Knee Osteoarthritis and Traumatic Meniscal Tear Patients: Preliminary Results

M. Bigoni, M. Turati, P. Sacerdote, 2023, Journal of clinical medicine.

Beta-endorphin concentrations in peripheral blood mononuclear cells of patients with multiple sclerosis: effects of treatment with interferon beta.

V. Martinelli, G. Comi, P. Sacerdote, 2000, Archives of neurology.

Individual housing induces altered immuno-endocrine responses to psychological stress in male mice

P. Sacerdote, S. Parmigiani, A. Bartolomucci, 2003, Psychoneuroendocrinology.

Antiepileptic agents affect hypothalamic beta-endorphin concentrations.

P. Mantegazza, P. Sacerdote, A. Panerai, 1984, Journal of Neurochemistry.

Layer- and subregion-specific electrophysiological and morphological changes of the medial prefrontal cortex in a mouse model of neuropathic pain

M. Mitrić, F. Ferraguti, P. Sacerdote, 2019, Scientific Reports.

Baclofen prolongs the analgesic effect of fentanyl in man.

P. Mantegazza, P. Sacerdote, A. Panerai, 1985, British journal of anaesthesia.

Cellular Sources and Effects of Tumor Necrosis Factor‐α on Pituitary Cells and in the Central Nervous System a

S. Shammah, P. Ricciardi-Castagnoli, P. Sacerdote, 1990 .

Effects of NSAIDs on the Release of Calcitonin Gene-Related Peptide and Prostaglandin E2 from Rat Trigeminal Ganglia

V. Vellani, P. Sacerdote, S. Franchi, 2017, Mediators of inflammation.

The Effects of Alcoholism Pharmacotherapy on Immune Responses in Alcohol-Dependent Patients

P. Sacerdote, S. Franchi, A. Panerai, 2010 .

Adult Stem Cell as New Advanced Therapy for Experimental Neuropathic Pain Treatment

A. Vescovi, P. Sacerdote, S. Franchi, 2014, BioMed research international.

Effects of indomethacin and diclofenac on substance P induced chemotaxis of human monocytes and polymorphonuclear cells.

P. Sacerdote, A. Panerai, L. Locatelli, 1992, Pharmacological research.

Increased substance P and tumor necrosis factor-α level in the paws following formalin injection in rat tail

P. Sacerdote, G. Biella, P. Ferrario, 2004, Brain Research.

Transient early expression of TNF-α in sciatic nerve and dorsal root ganglia in a mouse model of painful peripheral neuropathy

P. Sacerdote, S. Franchi, A. Panerai, 2008, Neuroscience Letters.

Centrally injected nerve growth factor modulates peripheral immune responses in the rat.

P. Sacerdote, A. Panerai, A. Micera, 1996, Neuroendocrinology.

The VGF-derived peptide TLQP-21: A new modulatory peptide for inflammatory pain

M. Ciotti, P. Sacerdote, A. Moles, 2008, Neuroscience Letters.

Traditional acupuncture increases the content of beta-endorphin in immune cells and influences mitogen induced proliferation.

P. Sacerdote, A. Panerai, M. Bianchi, 1991, The American journal of Chinese medicine.

P. Sacerdote, S. Franchi, A. Panerai, 2007, Brain, Behavior, and Immunity.