J. Holder

Emiri T. Mandeville, K. Arai, E. Lo, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.

J. Holder, Stephen A. Smith, N. Patel, 2003, Diabetes.

Tryptophan–NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation

J. Holder, M. Hodson, S. Connor, 2005, Archives of Toxicology.

Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy.

Jimmy D Bell, S. Taylor-Robinson, P. So, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Intestinal Detoxification Limits the Activation of Hepatic Pregnane X Receptor by Lithocholic Acid

P. Clements, J. Holder, M. Parker, 2010, Drug Metabolism and Disposition.

Glycogen Synthase Kinase-3 Mediates Acetaminophen-Induced Apoptosis in Human Hepatoma Cells

J. Holder, G. Kass, N. Yaacob, 2005, Journal of Pharmacology and Experimental Therapeutics.

Transduction of human trophoblastic cells by replication-deficient recombinant viral vectors. Promoting cellular differentiation affects virus entry.

M. Weitzman, A. Davis, M. Halterman, 1998, The American journal of pathology.

Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells after Focal Cerebral Ischemia in Spontaneously Hypertensive Rats

Emiri T. Mandeville, K. Arai, E. Lo, 2016, Cell transplantation.

PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer

J. Holder, Gregory J. Murphy, Julie C. Holder, 2000 .

Insulin activates protein kinase B, inhibits glycogen synthase kinase‐3 and activates glycogen synthase by rapamycin‐insensitive pathways in skeletal muscle and adipose tissue

P. Cohen, J. van der Kaay, C. Downes, 1997, FEBS letters.

Biliary Proliferative Lesions in the Sprague-Dawley Rat

J. Cullen, J. Holder, Richard T. Miller, 2014, Toxicologic pathology.

Mechanisms of trophoblast-virus interaction.

J. Holder, J. Strauss, S. Parry, 1997, Journal of reproductive immunology.

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity

M. Ingelman-Sundberg, V. Lauschke, R. Weaver, 2016, Archives of Toxicology.

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.

J W Yates, A. Reith, J. Holder, 2000, Chemistry & biology.

Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma.

J. Holder, J. Clapham, H. Chapman, 1998, The Journal of pharmacology and experimental therapeutics.

Drug Discovery induced pluripotent stem cells a model for transforming drug discovery

J. Holder, 2011 .

Astrocyte-Derived Pentraxin 3 Supports Blood–Brain Barrier Integrity Under Acute Phase of Stroke

Emiri T. Mandeville, K. Arai, E. Lo, 2016, Stroke.

Association of polymorphism within the promoter of the tumor necrosis factor alpha gene with increased risk of preterm premature rupture of the fetal membranes.

M. Morgan, J. Holder, J. Strauss, 1999, American journal of obstetrics and gynecology.

Sensitivity of Normal, Paramalignant, and Malignant Human Urothelial Cells to Inhibitors of the Epidermal Growth Factor Receptor Signaling Pathway

Jennifer Southgate, J. Southgate, Nicola J. Maclaine, 2008, Molecular Cancer Research.

Role of PPAR γ and EGFR signalling in the urothelial terminal differentiation programme

J. Southgate, C. Varley, J. Holder, 2004, Journal of Cell Science.

PPAR-gamma agonists: therapeutic role in diabetes, inflammation and cancer.

J. Holder, J C Holder, G J Murphy, 2000, Trends in pharmacological sciences.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience.

Tony Burdett, Helen Parkinson, Heiko Zimmermann, 2017, Stem cell research.

Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

T. Willson, J. Auwerx, P. Chambon, 2004 .

Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter.

J. Holder, M. Coghlan, J. Clapham, 2004, Metabolism: clinical and experimental.

Differentiation-Associated Reprogramming of the Transforming Growth Factor β Receptor Pathway Establishes the Circuitry for Epithelial Autocrine/Paracrine Repair

J. Southgate, C. Varley, J. Holder, 2012, PloS one.

Non-thiazolidinedione antihyperglycaemic agents. Part 3 : The effects of stereochemistry on the potency of α-methoxy-β-phenylpropanoic acids

Stephen A. Smith, J. Holder, D. Eggleston, 1999 .

Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cells.

Emiri T. Mandeville, K. Arai, E. Lo, 2015, Bioorganic & medicinal chemistry letters.

The preferential uptake of very-low-density lipoprotein cholesteryl ester by rat liver in vivo.

J. Holder, V. Zammit, D. Robinson, 1990, The Biochemical journal.

Astrocyte-Derived Pentraxin 3 Supports Blood–Brain Barrier Integrity Under Acute Phase of Stroke

K. Arai, E. Lo, J. Holder, 2016, Stroke.

Effects of Aging on Neural Stem/Progenitor Cells and Oligodendrocyte Precursor Cells after Focal Cerebral Ischemia in Spontaneously Hypertensive Rats

K. Arai, E. Lo, J. Holder, 2016, Cell transplantation.