P. Agretti

发表

The Thyroid Disruptor 1,1,1-Trichloro-2,2-Bis(p-Chlorophenyl)-Ethane Appears to Be an Uncompetitive Inverse Agonist for the Thyrotropin Receptor

Maria Teresa Dell'Anno, M. Trincavelli, A. Pinchera, 2007, Journal of Pharmacology and Experimental Therapeutics.

Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells

A. Pinchera, P. Vitti, J. Bernal, 2007, Journal of endocrinological investigation.

Clinical features, risk of mass enlargement, and development of endocrine hyperfunction in patients with adrenal incidentalomas: a long-term follow-up study

P. Vitti, P. Agretti, M. Tonacchera, 2020, Endocrine.

Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 2000, The Journal of clinical endocrinology and metabolism.

Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms.

A. Pinchera, G. Ceccarini, L. Chiovato, 1999, The Journal of clinical endocrinology and metabolism.

Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 1998, Thyroid : official journal of the American Thyroid Association.

Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.

F. Cetani, A. Pinchera, L. Chiovato, 1998, The Journal of clinical endocrinology and metabolism.

TSH Elevations as the First Laboratory Evidence for Pseudohypoparathyroidism Type Ib (PHP‐Ib)

O. Mäkitie, P. Agretti, M. Tonacchera, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Patients affected by vitiligo and autoimmune diseases do not show antibodies interfering with the activity of the melanocortin 1 receptor

A. Pinchera, P. Vitti, A. Dimida, 2010, Journal of endocrinological investigation.

Effects of a thyroid-stimulating human monoclonal autoantibody (M22) on functional activity of LH and FSH receptors.

A. Pinchera, A. Dimida, P. Agretti, 2006, Thyroid : official journal of the American Thyroid Association.

Clinical characteristics and genetic analysis in women with premature ovarian insufficiency.

A. Pinchera, P. Vitti, E. Pucci, 2013, Maturitas.

Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules.

G. Bevilacqua, P. Agretti, M. Tonacchera, 2007, Thyroid : official journal of the American Thyroid Association.

Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.

A. Pinchera, F. Santini, G. Ceccarini, 2004, The Journal of clinical endocrinology and metabolism.

Metabolic engineering of the iodine content in Arabidopsis

A. Pinchera, P. Vitti, P. Perata, 2012, Scientific Reports.

Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation.

C. Marcocci, A. Pinchera, P. Vitti, 2005, European journal of endocrinology.

Identification and functional analysis of novel dual oxidase 2 (DUOX2) mutations in children with congenital or subclinical hypothyroidism.

A. Pinchera, P. Vitti, A. Dimida, 2011, The Journal of clinical endocrinology and metabolism.

Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland.

A. Pinchera, P. Vitti, A. Dimida, 2009, The Journal of clinical endocrinology and metabolism.

Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: identification of a novel sequence variant

A. Pinchera, F. Santini, L. Chiovato, 2007, Clinical endocrinology.

Thyroid resistance to TSH complicated by autoimmune thyroiditis.

A. Pinchera, L. Chiovato, P. Vitti, 2001, The Journal of clinical endocrinology and metabolism.

Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene.

A. Pinchera, L. Chiovato, P. Vitti, 2000, The Journal of clinical endocrinology and metabolism.

Expression of cAMP-responsive element binding protein and inducible cAMP early repressor in hyperfunctioning thyroid adenomas.

L. Chiovato, P. Vitti, A. Peri, 2002, European journal of endocrinology.

Sporadic nonautoimmune congenital hyperthyroidism due to a strong activating mutation of the thyrotropin receptor gene.

D. Larizza, A. Pinchera, G. Ceccarini, 2000, Thyroid : official journal of the American Thyroid Association.

Iodine fortification of vegetables improves human iodine nutrition: in vivo evidence for a new model of iodine prophylaxis.

A. Pinchera, P. Vitti, P. Perata, 2013, The Journal of clinical endocrinology and metabolism.

Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 2000, The Journal of clinical endocrinology and metabolism.

The Thyroid Disruptor DDT Appears to Be an Uncompetitive Inverse Agonist for the TSH Receptor

M. Trincavelli, A. Pinchera, P. Vitti, 2006 .

3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells.

A. Pinchera, P. Vitti, P. Agretti, 2011, Journal of molecular endocrinology.

Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism

P. Vitti, P. Agretti, M. Tonacchera, 2014, Journal of Endocrinological Investigation.

Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism.

A. Pinchera, L. Chiovato, P. Vitti, 2004, The Journal of clinical endocrinology and metabolism.

The sodium‐iodide symporter expression in placental tissue at different gestational age: an immunohistochemical study

A. Pinchera, P. Vitti, G. Bevilacqua, 2006, Clinical endocrinology.

The W520X mutation in the TSHR gene brings on subclinical hypothyroidism through an haploinsufficiency mechanism

P. Agretti, M. Tonacchera, R. Berardi, 2013, Journal of Endocrinological Investigation.

Sporadic congenital nonautoimmune hyperthyroidism caused by P639S mutation in thyrotropin receptor gene

A. Pinchera, P. Vitti, P. Agretti, 2012, European Journal of Pediatrics.

Genetic analysis of TTF-2 gene in children with congenital hypothyroidism and cleft palate, congenital hypothyroidism, or isolated cleft palate.

A. Pinchera, L. Chiovato, P. Vitti, 2004, Thyroid : official journal of the American Thyroid Association.

Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein

A. Pinchera, F. Santini, P. Vitti, 2011 .

Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissues.

C. Marcocci, A. Pinchera, L. Chiovato, 2002, European journal of endocrinology.

Transfection with the cDNA of the human thyrotropin receptor of a poorly differentiated rat thyroid cell line (FRT)

A. Pinchera, F. Santini, L. Chiovato, 1996, Journal of endocrinological investigation.

Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism.

P. Agretti, M. Tonacchera, E. Ballarini, 2009, The Journal of clinical endocrinology and metabolism.

Identification of two different phenotypes of patients with amiodarone-induced thyrotoxicosis and positive thyrotropin receptor antibody tests.

F. Basolo, F. Bogazzi, L. Bartalena, 2021, Thyroid : official journal of the American Thyroid Association.

Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.

A. Pinchera, J. Bernal, G. D. de Escobar, 2008, Endocrinology.

In vitro effects of natural phytoestrogens on sodium/iodide symporter mediated thyroid iodide uptake by using a differentiated TSH-dependent cell line

A. Dimida, P. Agretti, M. Tonacchera, 2018 .

Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells.

A. Pinchera, F. Santini, G. Ceccarini, 2001, European journal of endocrinology.

Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein

A. Pinchera, L. Chiovato, P. Vitti, 2003, Clinical endocrinology.

The sodium‐iodide symporter protein is always present at a low expression and confined to the cell membrane in nonfunctioning nonadenomatous nodules of toxic nodular goitre

A. Pinchera, L. Chiovato, P. Vitti, 2004, Clinical endocrinology.

Benign nonfunctioning thyroid adenomas are characterized by a defective targeting to cell membrane or a reduced expression of the sodium iodide symporter protein.

A. Pinchera, L. Chiovato, P. Vitti, 2002, The Journal of clinical endocrinology and metabolism.

Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.

A. Pinchera, L. Chiovato, P. Vitti, 2003, European journal of biochemistry.

Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter.

A. Pinchera, F. Santini, P. Vitti, 2004, Thyroid : official journal of the American Thyroid Association.

Mass spectrometry in the diagnosis of thyroid disease and in the study of thyroid hormone metabolism.

P. Agretti, A. Saba, R. Zucchi, 2020, Mass spectrometry reviews.

Genetic analysis of the follicle stimulating hormone receptor gene in women with polycystic ovary syndrome

A. Pinchera, P. Vitti, A. Dimida, 2006, Journal of endocrinological investigation.

In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity

A. Pinchera, F. Santini, G. Ceccarini, 2003, Journal of endocrinological investigation.

Characterization of a novel mutation V136L in bone morphogenetic protein 15 identified in a woman affected by POI

P. Agretti, M. Tonacchera, T. Simoncini, 2021, Journal of Ovarian Research.

Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours.

P. Vitti, A. Peri, M. Serio, 2003, European journal of endocrinology.

Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism

A. Boner, A. Dimida, P. Agretti, 2014, BMC Endocrine Disorders.

TSH receptor and Gsα genetic analysis in children with Down’s syndrome and subclinical hypothyroidism

Elena S. Di Martino, A. Pinchera, L. Chiovato, 2003, Journal of endocrinological investigation.

Poorly specific binding of thyroglobulin to orbital fibroblasts from patients with Graves’ ophthalmopathy

P. Agretti, S. Sellari-Franceschini, M. Marinò, 2005, Journal of endocrinological investigation.

MicroRNA expression profile helps to distinguish benign nodules from papillary thyroid carcinomas starting from cells of fine-needle aspiration.

A. Pinchera, T. Rago, P. Vitti, 2012, European journal of endocrinology.

Gonadotrophin receptor blocking antibodies measured by the use of cell lines stably expressing human gonadotrophin receptors are not detectable in women with 46,XX premature ovarian failure

A. Pinchera, L. Chiovato, P. Vitti, 2004, Clinical endocrinology.

Prevalence of activating thyrotropin receptor and Gsα gene mutations in paediatric thyroid toxic adenomas: a multicentric Italian study

M. Pelizzo, M. Segni, D. Larizza, 2013, Clinical endocrinology.

The different requirement of L-T4 therapy in congenital athyreosis compared with adult-acquired hypothyroidism suggests a persisting thyroid hormone resistance at the hypothalamic-pituitary level.

P. Vitti, P. Agretti, M. Tonacchera, 2014, European journal of endocrinology.

Measurement of urinary free cortisol by LC–MS–MS: adoption of a literature reference range and comparison with our current immunometric method

C. Marcocci, P. Vitti, P. Agretti, 2019, Journal of Endocrinological Investigation.

Screening for drugs potentially interfering with MCT8-mediated T3 transport in vitro identifies dexamethasone and some commonly used drugs as inhibitors of MCT8 activity

P. Vitti, A. Dimida, P. Agretti, 2021, Journal of Endocrinological Investigation.

Dexamethasone and Some Commonly Used Drugs Inhibit MCT8-mediated T3 Transport in Vitro

P. Vitti, A. Dimida, P. Agretti, 2021 .

TSH receptor antibodies do not alter the function of gonadotropin receptors stably expressed in eukaryotic cells.

F. Cetani, A. Pinchera, L. Chiovato, 2004, European journal of endocrinology.

Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter

P. Vitti, P. Agretti, M. Tonacchera, 2019, Journal of Endocrinological Investigation.

Functional studies of new TSH receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotrophinaemia

A. Pinchera, P. Vitti, P. Agretti, 2009, Clinical endocrinology.

Gene expression profile in functioning and non-functioning nodules of autonomous multinodular goiter from an area of iodine deficiency: unexpected common characteristics between the two entities

L. Chiovato, P. Agretti, M. Tonacchera, 2021, Journal of Endocrinological Investigation.

Presence of a putative steroidal allosteric site on glycoprotein hormone receptors.

M. Rossi, A. Dimida, P. Agretti, 2009, European journal of pharmacology.

Endothelin-1 Up-Regulates p115RhoGEF in Embryonic Rat Cardiomyocytes During the Hypertrophic Response

P. Agretti, M. Tonacchera, M. Mazzoni, 2008 .

Estradiol Serum Levels are Crucial to Understand Physiological/Clinical Setting in Both Sexes: Limits of Measurement of Low Estradiol and Evaluation of a Sensitive Immunoassay

P. Vitti, P. Agretti, M. Tonacchera, 2019, Biomarkers Journal.

Identification of TSH receptor mutations in three families with resistance to TSH

A. Pinchera, P. Vitti, P. Agretti, 2007, Clinical endocrinology.

Congenital hypothyroidism caused by a novel homozygous mutation in the thyroglobulin gene

P. Vitti, P. Agretti, M. Tonacchera, 2013, European Journal of Pediatrics.

Importance of total and measured free testosterone in diagnosis of male hypogonadism: immunoassay versus mass spectrometry in a population of healthy young/middle-aged blood donors

P. Agretti, A. Saba, M. Sessa, 2020, Journal of Endocrinological Investigation.

A fast method to detect cell surface expression of thyrotropin receptor (TSHr): the microchip flow cytometry analysis.

A. Pinchera, P. Vitti, A. Dimida, 2007, Thyroid : official journal of the American Thyroid Association.

Presence in the Pre-Surgical Fine-Needle Aspiration of Potential Thyroid Biomarkers Previously Identified in the Post-Surgical One

T. Rago, P. Vitti, F. Basolo, 2013, PloS one.

Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells

P. Agretti, M. Tonacchera, E. Seregni, 2004, Journal of endocrinological investigation.

Non-autoimmune subclinical hypothyroidism due to a mutation in TSH receptor: report on two brothers

C. Pignata, P. Agretti, M. Tonacchera, 2013, Italian Journal of Pediatrics.

Genetic markers to discriminate benign and malignant thyroid nodules with undetermined cytology in an area of borderline iodine deficiency

R. Musmanno, A. Pinchera, T. Rago, 2011, Journal of Endocrinological Investigation.

BRAF mutation analysis in thyroid nodules with indeterminate cytology: our experience on surgical management of patients with thyroid nodules from an area of borderline iodine deficiency

T. Rago, M. Scutari, P. Agretti, 2014, Journal of Endocrinological Investigation.

Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response.

P. Agretti, M. Tonacchera, M. Mazzoni, 2008, Journal of receptor and signal transduction research.

Electric and magnetic fields do not modify the biochemical properties of FRTL-5 cells

A. Dimida, P. Agretti, M. Tonacchera, 2011, Journal of endocrinological investigation.