M. Tonacchera

发表

The Thyroid Disruptor 1,1,1-Trichloro-2,2-Bis(p-Chlorophenyl)-Ethane Appears to Be an Uncompetitive Inverse Agonist for the Thyrotropin Receptor

Maria Teresa Dell'Anno, M. Trincavelli, A. Pinchera, 2007, Journal of Pharmacology and Experimental Therapeutics.

Rare diseases in clinical endocrinology: a taxonomic classification system

C. Marcocci, F. Cetani, M. Brandi, 2015, Journal of Endocrinological Investigation.

Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells

A. Pinchera, P. Vitti, J. Bernal, 2007, Journal of endocrinological investigation.

The Role of Nuclear Medicine in the Clinical Management of Benign Thyroid Disorders, Part 1: Hyperthyroidism

G. Mariani, P. Vitti, M. Tonacchera, 2020, The Journal of Nuclear Medicine.

Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules.

T. Rago, P. Vitti, F. Ciregia, 2016, Translational research : the journal of laboratory and clinical medicine.

Thyroglobulin autoantibodies switch to immunoglobulin (Ig)G1 and IgG3 subclasses and preserve their restricted epitope pattern after 131I treatment for Graves' hyperthyroidism: the activity of autoimmune disease influences subclass distribution but not epitope pattern of autoantibodies

P. Vitti, M. Tonacchera, P. Piaggi, 2014, Clinical and experimental immunology.

Assessment of nodular goitre.

Paolo Vitti, A. Pinchera, P. Vitti, 2010, Best practice & research. Clinical endocrinology & metabolism.

Clinical features, risk of mass enlargement, and development of endocrine hyperfunction in patients with adrenal incidentalomas: a long-term follow-up study

P. Vitti, P. Agretti, M. Tonacchera, 2020, Endocrine.

Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors.

C. Dominici, H. McDowell, A. Pinchera, 2006, Cancer genetics and cytogenetics.

Toxic Adenoma and Multinodular Toxic Goiter

M. Tonacchera, D. Führer, 2017 .

Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 2000, The Journal of clinical endocrinology and metabolism.

Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms.

A. Pinchera, G. Ceccarini, L. Chiovato, 1999, The Journal of clinical endocrinology and metabolism.

Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 1998, Thyroid : official journal of the American Thyroid Association.

Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.

F. Cetani, A. Pinchera, L. Chiovato, 1998, The Journal of clinical endocrinology and metabolism.

Influence of iodization programmes on the epidemiology of nodular goitre.

P. Vitti, M. Tonacchera, E. Fiore, 2014, Best practice & research. Clinical endocrinology & metabolism.

Radioiodine 131I treatment for large nodular goiter: recombinant human thyrotropin allows the reduction of radioiodine 131I activity to be administered in patients with low uptake.

A. Pinchera, P. Vitti, W. Bencivelli, 2011, Thyroid : official journal of the American Thyroid Association.

Failure to detect thyroid growth-promoting activity in immunoglobulin G of patients with endemic goiter.

A. Pinchera, L. Chiovato, P. Vitti, 1994, The Journal of clinical endocrinology and metabolism.

Thyroid-stimulating hormone levels in the first days of life and perinatal factors associated with sub-optimal neuromotor outcome in pre-term infants

G. Cioni, A. Pinchera, A. Guzzetta, 2011, Journal of endocrinological investigation.

TSH Elevations as the First Laboratory Evidence for Pseudohypoparathyroidism Type Ib (PHP‐Ib)

O. Mäkitie, P. Agretti, M. Tonacchera, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Blood Cell Mitochondrial DNA Content and Premature Ovarian Aging

S. Bione, P. Vineis, D. Mari, 2012, PloS one.

Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor.

F. Cetani, M. Tonacchera, S. Costagliola, 1996, European journal of endocrinology.

Clinical and Metabolic Effects of Alpha-Lipoic Acid Associated with Two Different Doses of Myo-Inositol in Women with Polycystic Ovary Syndrome

M. Tonacchera, E. Benelli, F. Fruzzetti, 2020, International journal of endocrinology.

Patients affected by vitiligo and autoimmune diseases do not show antibodies interfering with the activity of the melanocortin 1 receptor

A. Pinchera, P. Vitti, A. Dimida, 2010, Journal of endocrinological investigation.

Studies on the in vitro cytotoxic effect of amiodarone.

A. Pinchera, F. Santini, L. Chiovato, 1994, Endocrinology.

Effects of a thyroid-stimulating human monoclonal autoantibody (M22) on functional activity of LH and FSH receptors.

A. Pinchera, A. Dimida, P. Agretti, 2006, Thyroid : official journal of the American Thyroid Association.

Clinical characteristics and genetic analysis in women with premature ovarian insufficiency.

A. Pinchera, P. Vitti, E. Pucci, 2013, Maturitas.

Graves' Disease and the Post-partum Period: An Intriguing Relationship

M. Rotondi, M. Tonacchera, G. Di Dalmazi, 2019, Front. Endocrinol..

Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients

V. D. Di Crescenzo, M. Tonacchera, Anna Guerra, 2013, BMC Surgery.

Herpes virus associato a tiroidite di Hashimoto Human herpes virus associated with Hashimoto ’ s thyroiditis

M. Tonacchera, M. Vitale, C. Carlomagno, 2013 .

Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules.

G. Bevilacqua, P. Agretti, M. Tonacchera, 2007, Thyroid : official journal of the American Thyroid Association.

Thyroid autoimmunity may represent a predisposition for the development of fibromyalgia?

S. Bombardieri, M. Tonacchera, A. Rossi, 2012, Rheumatology International.

Patients with Indeterminate Thyroid Nodules at Cytology and Cancer at Histology Have a More Favorable Outcome Compared with Patients with Suspicious or Malignant Cytology.

T. Rago, M. Scutari, P. Vitti, 2018, Thyroid : official journal of the American Thyroid Association.

Familial Non-Medullary Thyroid Carcinoma in Pediatric Age: Our Surgical Experience

M. Tonacchera, G. Materazzi, R. Morganti, 2021, World Journal of Surgery.

Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.

A. Pinchera, F. Santini, G. Ceccarini, 2004, The Journal of clinical endocrinology and metabolism.

Metabolic engineering of the iodine content in Arabidopsis

A. Pinchera, P. Vitti, P. Perata, 2012, Scientific Reports.

Autoimmune hypothyroidism and hyperthyroidism in patients with Turner's syndrome.

D. Larizza, R. Lorini, A. Pinchera, 1996, European journal of endocrinology.

Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation.

C. Marcocci, A. Pinchera, P. Vitti, 2005, European journal of endocrinology.

Effect of aging on clinical features and metabolic complications of women with polycystic ovary syndrome

E. Pucci, M. Tonacchera, A. Molinaro, 2021, Journal of Endocrinological Investigation.

Identification and functional analysis of novel dual oxidase 2 (DUOX2) mutations in children with congenital or subclinical hypothyroidism.

A. Pinchera, P. Vitti, A. Dimida, 2011, The Journal of clinical endocrinology and metabolism.

Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland.

A. Pinchera, P. Vitti, A. Dimida, 2009, The Journal of clinical endocrinology and metabolism.

Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: identification of a novel sequence variant

A. Pinchera, F. Santini, L. Chiovato, 2007, Clinical endocrinology.

Thyroid resistance to TSH complicated by autoimmune thyroiditis.

A. Pinchera, L. Chiovato, P. Vitti, 2001, The Journal of clinical endocrinology and metabolism.

Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene.

A. Pinchera, L. Chiovato, P. Vitti, 2000, The Journal of clinical endocrinology and metabolism.

A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women

M. Tonacchera, E. Benelli, C. Di Cosmo, 2016, International journal of endocrinology.

Thyroid and menopause

P. Vitti, M. Tonacchera, S. Del Ghianda, 2014, Climacteric : the journal of the International Menopause Society.

TSH receptor and disease

F. Cetani, J. Parma, M. Tonacchera, 1996, Clinical endocrinology.

Expression of cAMP-responsive element binding protein and inducible cAMP early repressor in hyperfunctioning thyroid adenomas.

L. Chiovato, P. Vitti, A. Peri, 2002, European journal of endocrinology.

Immature Thymocytes: A Clue to the Riddle Antibodies (TSAbs) Induce the Activation of Graves' Disease TSHR-Stimulating

M. Giménez-Barcons, M. Tonacchera, A. Marín-Sánchez, 2015 .

Detection of antibodies blocking thyrotropin effect using Chinese hamster ovary cells transfected with the cloned human TSH receptor

A. Pinchera, F. Santini, L. Chiovato, 1994, Journal of endocrinological investigation.

Sporadic nonautoimmune congenital hyperthyroidism due to a strong activating mutation of the thyrotropin receptor gene.

D. Larizza, A. Pinchera, G. Ceccarini, 2000, Thyroid : official journal of the American Thyroid Association.

Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.

S. Swillens, F. Cetani, J. Parma, 1996, The Journal of clinical endocrinology and metabolism.

Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.

S. Swillens, J. Parma, M. Tonacchera, 1995, Molecular endocrinology.

Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors

F. Cetani, M. Tonacchera, G. Vassart, 1996, FEBS letters.

Iodine fortification of vegetables improves human iodine nutrition: in vivo evidence for a new model of iodine prophylaxis.

A. Pinchera, P. Vitti, P. Perata, 2013, The Journal of clinical endocrinology and metabolism.

Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter.

A. Pinchera, G. Ceccarini, L. Chiovato, 2000, The Journal of clinical endocrinology and metabolism.

The Thyroid Disruptor DDT Appears to Be an Uncompetitive Inverse Agonist for the TSH Receptor

M. Trincavelli, A. Pinchera, P. Vitti, 2006 .

Detection of 3-iodothyronamine in human patients: a preliminary study.

P. Vitti, M. Tonacchera, T. Scanlan, 2012, The Journal of clinical endocrinology and metabolism.

3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells.

A. Pinchera, P. Vitti, P. Agretti, 2011, Journal of molecular endocrinology.

Tissue distribution and cardiac metabolism of 3-iodothyronamine.

P. Vitti, M. Tonacchera, T. Scanlan, 2010, Endocrinology.

Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism

P. Vitti, P. Agretti, M. Tonacchera, 2014, Journal of Endocrinological Investigation.

Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism.

A. Pinchera, L. Chiovato, P. Vitti, 2004, The Journal of clinical endocrinology and metabolism.

The sodium‐iodide symporter expression in placental tissue at different gestational age: an immunohistochemical study

A. Pinchera, P. Vitti, G. Bevilacqua, 2006, Clinical endocrinology.

Maturation of pituitary-thyroid function in the anencephalic fetus.

P. Vitti, M. Tonacchera, P. Beck‐Peccoz, 1992, Acta medica Austriaca.

The W520X mutation in the TSHR gene brings on subclinical hypothyroidism through an haploinsufficiency mechanism

P. Agretti, M. Tonacchera, R. Berardi, 2013, Journal of Endocrinological Investigation.

The effect of voluntary iodine prophylaxis in a small rural community: the Pescopagano survey 15 years later.

A. Pinchera, T. Rago, P. Vitti, 2013, The Journal of clinical endocrinology and metabolism.

Sporadic congenital nonautoimmune hyperthyroidism caused by P639S mutation in thyrotropin receptor gene

A. Pinchera, P. Vitti, P. Agretti, 2012, European Journal of Pediatrics.

Iodine status and supplementation in pregnancy: an overview of the evidence provided by meta-analyses

M. Rotondi, L. Chiovato, E. Pearce, 2022, Reviews in Endocrine and Metabolic Disorders.

Genetic analysis of TTF-2 gene in children with congenital hypothyroidism and cleft palate, congenital hypothyroidism, or isolated cleft palate.

A. Pinchera, L. Chiovato, P. Vitti, 2004, Thyroid : official journal of the American Thyroid Association.

Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein

A. Pinchera, F. Santini, P. Vitti, 2011 .

Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissues.

C. Marcocci, A. Pinchera, L. Chiovato, 2002, European journal of endocrinology.

Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor.

A. Pinchera, L. Chiovato, T. Rago, 1993, The Journal of clinical endocrinology and metabolism.

Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin

A. Pinchera, L. Chiovato, P. Vitti, 1993, Journal of endocrinological investigation.

Hyperthyroidism and pregnancy. An Italian Thyroid Association (AIT) and Italian Association of Clinical Endocrinologists (AME) joint statement for clinical practice

E. Papini, R. Negro, A. Pinchera, 2011 .

Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism.

P. Agretti, M. Tonacchera, E. Ballarini, 2009, The Journal of clinical endocrinology and metabolism.

Identification of two different phenotypes of patients with amiodarone-induced thyrotoxicosis and positive thyrotropin receptor antibody tests.

F. Basolo, F. Bogazzi, L. Bartalena, 2021, Thyroid : official journal of the American Thyroid Association.

Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.

A. Pinchera, J. Bernal, G. D. de Escobar, 2008, Endocrinology.

Effect of long- and short-chain perfluorinated compounds on cultured thyroid cells viability and response to TSH

M. Rotondi, L. Chiovato, M. Tonacchera, 2019, Journal of Endocrinological Investigation.

In vitro effects of natural phytoestrogens on sodium/iodide symporter mediated thyroid iodide uptake by using a differentiated TSH-dependent cell line

A. Dimida, P. Agretti, M. Tonacchera, 2018 .

Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells.

A. Pinchera, F. Santini, G. Ceccarini, 2001, European journal of endocrinology.

Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein

A. Pinchera, L. Chiovato, P. Vitti, 2003, Clinical endocrinology.

The sodium‐iodide symporter protein is always present at a low expression and confined to the cell membrane in nonfunctioning nonadenomatous nodules of toxic nodular goitre

A. Pinchera, L. Chiovato, P. Vitti, 2004, Clinical endocrinology.

Benign nonfunctioning thyroid adenomas are characterized by a defective targeting to cell membrane or a reduced expression of the sodium iodide symporter protein.

A. Pinchera, L. Chiovato, P. Vitti, 2002, The Journal of clinical endocrinology and metabolism.

Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.

A. Pinchera, L. Chiovato, P. Vitti, 2003, European journal of biochemistry.

Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas

F. Cetani, A. Pinchera, R. Barsacchi, 1999, Journal of endocrinological investigation.

Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter.

A. Pinchera, F. Santini, P. Vitti, 2004, Thyroid : official journal of the American Thyroid Association.

In vivo assessment about the effects of a diet containing iodine-enriched foodstuffs. A pilot study in 30 volunteers

A. Pinchera, P. Vitti, F. Aghini‐Lombardi, 2012, Journal of Endocrinological Investigation.

Iodine contributes to thyroid autoimmunity in humans by unmasking a cryptic epitope on thyroglobulin.

T. Rago, M. Scutari, P. Vitti, 2013, The Journal of clinical endocrinology and metabolism.

Genetic mutations in the treatment of anaplastic thyroid cancer: a systematic review

V. D. Di Crescenzo, M. Tonacchera, Anna Guerra, 2013, BMC Surgery.

The G Protein–coupled Receptor Family and One of Its Members, the TSH Receptor a

P. Vanderhaeghen, M. Parmentier, J. Parma, 1995, Annals of the New York Academy of Sciences.

Somatic and germline mutations of the TSH receptor gene in thyroid diseases.

S. Swillens, J. Parma, M. Tonacchera, 1995, The Journal of clinical endocrinology and metabolism.

Thyroid autoimmunity and female gender

A. Pinchera, L. Chiovato, M. Tonacchera, 1993, Journal of endocrinological investigation.

Genetic analysis of the follicle stimulating hormone receptor gene in women with polycystic ovary syndrome

A. Pinchera, P. Vitti, A. Dimida, 2006, Journal of endocrinological investigation.

In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity

A. Pinchera, F. Santini, G. Ceccarini, 2003, Journal of endocrinological investigation.

Thyroid function and thyroid autoimmunity independently modulate serum concentration of soluble interleukin 2 (IL‐2) receptor (sIL‐2R) in thyroid diseases

G. Barbesino, M. Tonacchera, M. Marino, 1992, Clinical endocrinology.

Genetics and phenomics of hypothyroidism and thyroid dys- and agenesis due to PAX8 and TTF1 mutations

M. Tonacchera, L. Montanelli, 2010, Molecular and Cellular Endocrinology.

Human herpes virus associated with Hashimoto's thyroiditis.

V. D. Di Crescenzo, M. Tonacchera, M. Vitale, 2013, Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive.

Characterization of a novel mutation V136L in bone morphogenetic protein 15 identified in a woman affected by POI

P. Agretti, M. Tonacchera, T. Simoncini, 2021, Journal of Ovarian Research.

Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.

M. Tonacchera, S. Costagliola, G. Vassart, 1994, Endocrinology.

The thyroperoxidase doublet is not produced by alternative splicing

F. Cetani, M. Tonacchera, S. Costagliola, 1995, Molecular and Cellular Endocrinology.

Functional characteristics of a variant thyrotropin receptor.

F. Cetani, M. Tonacchera, S. Costagliola, 1996, European journal of biochemistry.

Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours.

P. Vitti, A. Peri, M. Serio, 2003, European journal of endocrinology.

Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism

A. Boner, A. Dimida, P. Agretti, 2014, BMC Endocrine Disorders.

Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors.

F. Cetani, M. Tonacchera, S. Costagliola, 1998, The Journal of clinical endocrinology and metabolism.

TSH receptor and Gsα genetic analysis in children with Down’s syndrome and subclinical hypothyroidism

Elena S. Di Martino, A. Pinchera, L. Chiovato, 2003, Journal of endocrinological investigation.

Treatment of Graves’ hyperthyroidism with thionamides: a position paper on indications and safety in pregnancy

L. Chiovato, P. Vitti, L. Bartalena, 2019, Journal of Endocrinological Investigation.

Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R.

M. Tonacchera, S. Costagliola, G. Vassart, 1994, Biochemical and biophysical research communications.

The Italian screening program for primary congenital hypothyroidism: Actions to improve screening, diagnosis, follow-up, and surveillance

V. Stoppioni, F. Mosca, M. Tonacchera, 2013, Journal of Endocrinological Investigation.

Pregnancy outcome in women treated with methimazole or propylthiouracil during pregnancy

P. Macchia, L. Chiovato, P. Vitti, 2015, Journal of Endocrinological Investigation.

Two Italian kindreds with familial hypocalciuric hypercalcaemia caused by loss‐of‐function mutations in the calcium‐sensing receptor (CaR) gene: functional characterization of a novel CaR missense mutation

C. Marcocci, F. Cetani, A. Pinchera, 2003, Clinical endocrinology.

Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.

R. Paschke, J. Parma, M. Tonacchera, 1994, The Journal of clinical endocrinology and metabolism.

Constitutively active receptors as a disease-causing mechanism

R. Paschke, J. Parma, M. Tonacchera, 1994, Molecular and Cellular Endocrinology.

MicroRNA expression profile helps to distinguish benign nodules from papillary thyroid carcinomas starting from cells of fine-needle aspiration.

A. Pinchera, T. Rago, P. Vitti, 2012, European journal of endocrinology.

Gonadotrophin receptor blocking antibodies measured by the use of cell lines stably expressing human gonadotrophin receptors are not detectable in women with 46,XX premature ovarian failure

A. Pinchera, L. Chiovato, P. Vitti, 2004, Clinical endocrinology.

Post-partum and non-post-partum relapsing Graves' hyperthyroidism display different response to anti-thyroid drugs.

M. Rotondi, L. Chiovato, M. Tonacchera, 2018, European journal of endocrinology.

Prevalence of activating thyrotropin receptor and Gsα gene mutations in paediatric thyroid toxic adenomas: a multicentric Italian study

M. Pelizzo, M. Segni, D. Larizza, 2013, Clinical endocrinology.

Oncogenic mutations in thyroid adenoma: methodological criteria.

F. Cetani, J. Parma, M. Tonacchera, 1996, European journal of endocrinology.

The different requirement of L-T4 therapy in congenital athyreosis compared with adult-acquired hypothyroidism suggests a persisting thyroid hormone resistance at the hypothalamic-pituitary level.

P. Vitti, P. Agretti, M. Tonacchera, 2014, European journal of endocrinology.

Evidence for the secretion of thyrotropin with enhanced bioactivity in syndromes of thyroid hormone resistance.

P. Vitti, M. Tonacchera, P. Beck‐Peccoz, 1994, The Journal of clinical endocrinology and metabolism.

Screening for drugs potentially interfering with MCT8-mediated T3 transport in vitro identifies dexamethasone and some commonly used drugs as inhibitors of MCT8 activity

P. Vitti, A. Dimida, P. Agretti, 2021, Journal of Endocrinological Investigation.

Dexamethasone and Some Commonly Used Drugs Inhibit MCT8-mediated T3 Transport in Vitro

P. Vitti, A. Dimida, P. Agretti, 2021 .

Best Practice & Research Clinical Endocrinology & Metabolism

A. Pinchera, P. Vitti, M. Tonacchera, 2010 .

The large majority of 1520 patients with indeterminate thyroid nodule at cytology have a favorable outcome, and a clinical risk score has a high negative predictive value for a more cumbersome cancer disease.

T. Rago, M. Scutari, P. Vitti, 2014, The Journal of clinical endocrinology and metabolism.

Tako-tsubo Syndrome as First Manifestation in a Case of Pheochromocytoma Developed From a Non-functional Adrenal Incidentaloma

P. Vitti, M. Tonacchera, E. Molinaro, 2020, Frontiers in Endocrinology.

Incidence of antibodies blocking thyrotropin effect in vitro in patients with euthyroid or hypothyroid autoimmune thyroiditis.

A. Pinchera, F. Santini, L. Chiovato, 1990, The Journal of clinical endocrinology and metabolism.

Graves’ Disease TSHR-Stimulating Antibodies (TSAbs) Induce the Activation of Immature Thymocytes: A Clue to the Riddle of TSAbs Generation?

M. Giménez-Barcons, M. Tonacchera, R. Abella, 2015, The Journal of Immunology.

Humoral thyroid autoimmunity is not involved in the pathogenesis of myxedematous endemic cretinism.

F. Santini, L. Chiovato, P. Vitti, 1995, The Journal of clinical endocrinology and metabolism.

TSH-Blocking Antibodies and Congenital Hypothyroidism

C. Marcocci, A. Pinchera, F. Santini, 1989 .

TSH receptor antibodies do not alter the function of gonadotropin receptors stably expressed in eukaryotic cells.

F. Cetani, A. Pinchera, L. Chiovato, 2004, European journal of endocrinology.

Thyroid hypoechogenic pattern at ultrasonography as a tool for predicting recurrence of hyperthyroidism after medical treatment in patients with Graves' disease.

L Chiovato, M Tonacchera, A Pinchera, 1992, Acta endocrinologica.

Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter

P. Vitti, P. Agretti, M. Tonacchera, 2019, Journal of Endocrinological Investigation.

Evaluation of L-thyroxine replacement therapy in children with congenital hypothyroidism

A. Pinchera, L. Chiovato, M. Tonacchera, 1991, Journal of endocrinological investigation.

Mapping thyroid peroxidase epitopes using recombinant protein fragments.

R. Uibo, F. Cetani, M. Tonacchera, 1995, European journal of endocrinology.

Functional studies of new TSH receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotrophinaemia

A. Pinchera, P. Vitti, P. Agretti, 2009, Clinical endocrinology.

The iodine nutritional status in the Italian population: data from the Italian National Observatory for Monitoring Iodine Prophylaxis (OSNAMI) (period 2015-2019).

S. Andò, M. Tonacchera, C. Mian, 2019, The American journal of clinical nutrition.

Iodine Deficiency from Pregnancy to Childhood

P. Vitti, M. Tonacchera, C. Cosmo, 2015 .

Gene expression profile in functioning and non-functioning nodules of autonomous multinodular goiter from an area of iodine deficiency: unexpected common characteristics between the two entities

L. Chiovato, P. Agretti, M. Tonacchera, 2021, Journal of Endocrinological Investigation.

Uptake of amiodarone by thyroidal and non-thyroidal cell lines

P. Vitti, F. Bogazzi, L. Bartalena, 2006, Journal of endocrinological investigation.

Presence of a putative steroidal allosteric site on glycoprotein hormone receptors.

M. Rossi, A. Dimida, P. Agretti, 2009, European journal of pharmacology.

Endothelin-1 Up-Regulates p115RhoGEF in Embryonic Rat Cardiomyocytes During the Hypertrophic Response

P. Agretti, M. Tonacchera, M. Mazzoni, 2008 .

Estradiol Serum Levels are Crucial to Understand Physiological/Clinical Setting in Both Sexes: Limits of Measurement of Low Estradiol and Evaluation of a Sensitive Immunoassay

P. Vitti, P. Agretti, M. Tonacchera, 2019, Biomarkers Journal.

Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease.

Luca Chiovato, Paolo Vitti, Stefano Milani, 2002, The American journal of pathology.

A Not So Benign Family Pedigree With Hereditary Chorea: A Broader Phenotypic Expression or Additional Picture?

A. Guzzetta, R. Battini, M. Tonacchera, 2019, Child neurology open.

Hypothyroidism, Systemic Manifestations of

L. Chiovato, M. Tonacchera, 2004 .

Identification of TSH receptor mutations in three families with resistance to TSH

A. Pinchera, P. Vitti, P. Agretti, 2007, Clinical endocrinology.

Thyrotropin receptor polymorphisms and thyroid diseases.

A. Pinchera, M. Tonacchera, 2000, The Journal of clinical endocrinology and metabolism.

Congenital hypothyroidism caused by a novel homozygous mutation in the thyroglobulin gene

P. Vitti, P. Agretti, M. Tonacchera, 2013, European Journal of Pediatrics.

Low Elasticity of Thyroid Nodules on Ultrasound Elastography Is Correlated with Malignancy, Degree of Fibrosis, and High Expression of Galectin-3 and Fibronectin-1.

F. Santini, T. Rago, M. Scutari, 2017, Thyroid : official journal of the American Thyroid Association.

A fast method to detect cell surface expression of thyrotropin receptor (TSHr): the microchip flow cytometry analysis.

A. Pinchera, P. Vitti, A. Dimida, 2007, Thyroid : official journal of the American Thyroid Association.

PFOA, PFHxA and C6O4 differently modulate the expression of CXCL8 in normal thyroid cells and in thyroid cancer cell lines

M. Rotondi, L. Chiovato, M. Tonacchera, 2023, Environmental Science and Pollution Research.

Systemic Manifestations of Hypothyroidism

L. Chiovato, M. Tonacchera, 2014 .

Hyperthyroidism and pregnancy. An Italian Thyroid Association (AIT) and Italian Association of Clinical Endocrinologists (AME) joint statement for clinical practice.

E. Papini, R. Negro, A. Pinchera, 2011, Journal of endocrinological investigation.

Presence in the Pre-Surgical Fine-Needle Aspiration of Potential Thyroid Biomarkers Previously Identified in the Post-Surgical One

T. Rago, P. Vitti, F. Basolo, 2013, PloS one.

Radioiodide induces apoptosis in human thyroid tissue in culture

M. Tonacchera, A. Colao, V. Marotta, 2013, Endocrine.

Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells

P. Agretti, M. Tonacchera, E. Seregni, 2004, Journal of endocrinological investigation.

Non-autoimmune subclinical hypothyroidism due to a mutation in TSH receptor: report on two brothers

C. Pignata, P. Agretti, M. Tonacchera, 2013, Italian Journal of Pediatrics.

11 The cAMP in thyroid

A. Allgeier, M. Parmentier, C. Ledent, 1997 .

Detection of Circulating Autoantibodies Against Thyroid Hormones in an Infant with Permanent Congenital Hypothyroidism and her Twin with Transient Congenital Hypothyroidism: Possible Contribution of Thyroid Hormone Autoantibodies to Neonatal and Infant Hypothyroidism

E. Pearce, L. Braverman, M. Tonacchera, 2008, Journal of pediatric endocrinology & metabolism : JPEM.

Genetic markers to discriminate benign and malignant thyroid nodules with undetermined cytology in an area of borderline iodine deficiency

R. Musmanno, A. Pinchera, T. Rago, 2011, Journal of Endocrinological Investigation.

BRAF mutation analysis in thyroid nodules with indeterminate cytology: our experience on surgical management of patients with thyroid nodules from an area of borderline iodine deficiency

T. Rago, M. Scutari, P. Agretti, 2014, Journal of Endocrinological Investigation.

Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response.

P. Agretti, M. Tonacchera, M. Mazzoni, 2008, Journal of receptor and signal transduction research.

The effect of voluntary iodine prophylaxis in a small rural community: the Pescopagano survey 15 years later.

A. Pinchera, T. Rago, P. Vitti, 2013, The Journal of clinical endocrinology and metabolism.

Activating mutations of the TSH receptor gene cause thyroid diseases.

S. Swillens, J. Parma, M. Tonacchera, 1996, Annales d'endocrinologie.

Electric and magnetic fields do not modify the biochemical properties of FRTL-5 cells

A. Dimida, P. Agretti, M. Tonacchera, 2011, Journal of endocrinological investigation.

The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis.

A. Allgeier, M. Parmentier, C. Ledent, 1997, Advances in second messenger and phosphoprotein research.