A. Brouwer

P. Leonards, A. Brouwer, J. Klungsøyr, 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Contribution of planar (0-1 ortho) and nonplanar (2-4 ortho) fractions of Aroclor 1260 to the induction of altered hepatic foci in female Sprague-Dawley rats.

A. Bergman, A. Brouwer, J. Koeman, 2000, Toxicology and applied pharmacology.

Induction of altered hepatic foci by a mixture of dioxin-like compounds with and without 2,2',4,4',5,5'-hexachlorobiphenyl in female Sprague-Dawley rats.

M. van den Berg, A. Brouwer, J. Koeman, 1999, Toxicology and applied pharmacology.

Toxicokinetics of an environmentally relevant mixture of dioxin-like PHAHs with or without a non-dioxin-like PCB in a semi-chronic exposure study in female Sprague Dawley rats.

M. van den Berg, A. Brouwer, J. de Jongh, 1998, Chemosphere.

Comprehensive evaluation of dioxins and dioxin-like compounds in surface soils and river sediments from e-waste-processing sites in a village in northern Vietnam: Heading towards the environmentally sound management of e-waste

H. Takigami, Shin Takahashi, S. Tanabe, 2016 .

Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands.

A. Brouwer, L. Meijer, P. Sauer, 2008, Environmental science & technology.

Antimicrobial activity and carbohydrate metabolism in the bacterial metagenome of the soil-living invertebrate Folsomia candida

A. Brouwer, N. V. van Straalen, D. Roelofs, 2019, Scientific Reports.

Evaluation of a panel of in vitro methods for assessing thyroid receptor β and transthyretin transporter disrupting activities.

E. Simon, B. van der Burg, A. Brouwer, 2020, Reproductive toxicology.

Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.

R. Houtman, A. Brouwer, I. Rietjens, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

High induction of cytochrome p4501a activity without changes in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin

A. Brouwer, J. Koeman, E. van Santen, 1997 .

Dioxin type and mixed type induction of the cytochrome P-450 system of common eider ducklings (Somateria mollissima) by PCBs: with indications for biotransformation.

A. Brouwer, A. Murk, J. Boon, 1995 .

Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition.

M. E. Hahn, S. Karchner, A. Brouwer, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity.

N. Vermeulen, T. Visser, J. Meerman, 2005, Chemical research in toxicology.

Alterations in plasma and hepatic retinoid levels in flounder (Platichthys flesus) after chronic exposure to contaminated harbour sludge in a mesocosm study

A. Brouwer, J. Koeman, A. Vethaak, 1998 .

Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats.

I. Meerts, S. Hoving, A. Brouwer, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Induction of biotransformation enzymes by polyhalogenated aromatic hydrocarbons (PHAHs): potential impact on animal physiology and health

A. Brouwer, 1999 .

Report of the WHO working group on the assessment of health risks for human infants from exposure to PCDDs, PCDFs and PCBs.

M. Feeley, F. R. van Leeuwen, A. Brouwer, 1998, Chemosphere.

Metabolism and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl in pregnant and fetal rats.

P. van Bladeren, A. Brouwer, E. Wehler, 1995, Chemico-biological interactions.

SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part II–field feasibility survey

Abraham Brouwer, Ron van der Oost, Giulia Sileno, 2017, Environmental toxicology and chemistry.

Low hepatic 7-ethoxyresorufin-O-deethylase (EROD) activity and minor alterations in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50.

A. Brouwer, J. Koeman, E. Roex, 1996, Environmental pollution.

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive.

Timo Hamers, Werner Brack, Henner Hollert, 2018, The Science of the total environment.

Steroid hormonal bioactivities, culprit natural and synthetic hormones and other emerging contaminants in waste water measured using bioassays and UPLC-tQ-MS.

A. Brouwer, C. Houtman, R. ten Broek, 2018, The Science of the total environment.

Versicolorin A enhances the genotoxicity of Aflatoxin B1 in human liver cells by inducing the transactivation of the Ah-Receptor.

B. van der Burg, A. Brouwer, B. V. van Vugt-Lussenburg, 2021, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DRhuman CALUX reporter gene assay.

B. van der Burg, A. Brouwer, B. V. van Vugt-Lussenburg, 2021, Chemosphere.

Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays.

B. van der Burg, A. Brouwer, S. Hamm, 2020, Chemosphere.

Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47).

T. Visser, T. Hamers, A. Brouwer, 2008, Molecular nutrition & food research.

Interference between Progesterone and Dioxin Signal

A. Brouwer, B. Burg, P. V. D. Saag, 1998 .

The calux (chemical‐activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma

P. Leonards, A. Brouwer, M. Denison, 1997 .

Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment.

M. van den Berg, A. Brouwer, J. Koeman, 1995, European journal of pharmacology.

The use of biochemical parameters in comparative toxicological studies with the cormorant () in the Netherlands

A. Brouwer, T. Sinnige, M. Berg, 1992 .

Inhibition of intercellular communication and induction of ethoxyresorufin-O-deethylase activity by polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans in mouse hepa1c1c7 cells.

A. Brouwer, J. Koeman, B. de Roos, 1996, Environmental toxicology and pharmacology.

Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines.

H. van Loveren, A. Liem, P. Reijnders, 1995, Chemosphere.

Effects of Polychlorinated Biphenyls (PCBs) and Dioxins on Growth and Development

C. Koopman‐Esseboom, A. Brouwer, N. Weisglas‐Kuperus, 1994, Human & experimental toxicology.

3,4,3',4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. I. Serum and Hepatic Retinoid Reduction and Morphologic Changes

A. Brouwer, S. Durham, 1989, Toxicologic pathology.

3,4,3,4'-Tetrachlorobiphenyl-Induced Effects in the Rat Liver. II. Electron Microscopic Autoradiographic Localization of H-TCB

A. Brouwer, S. Durham, 1989, Toxicologic pathology.

Host resistance to rat cytomegalovirus (RCMV) and immune function in adult PVG rats fed herring from the contaminated Baltic Sea

A. Osterhaus, A. Brouwer, H. Loveren, 1996, Archives of Toxicology.

Biochemical and toxic effects of polychlorinated biphenyls (PCBs), dibenzo-P-dioxins (PCDDs) and dibenzofurans (PCDFs) in the cormorant (phalacrocorax carbo) after in ovo exposure

A. Brouwer, S. Dirksen, M. Gaag, 1994 .

Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms.

P. Chambon, H. Nau, A. Brouwer, 2005, Chemico-biological interactions.

Interference of polychlorinated biphenyls in thyroid hormone metabolism: possible neurotoxic consequences in fetal and neonatal rats.

A. Brouwer, D. Morse, H. Koeter, 1992 .

Time and dose responses of the reduction in retinoid concentrations in C57BL/Rij and DBA/2 mice induced by 3,4,3',4'-tetrachlorobiphenyl.

A. Brouwer, A. Kukler, K. J. van den Berg, 1985, Toxicology and applied pharmacology.

Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan.

H. Takigami, A. Brouwer, T. Isobe, 2015, The Science of the total environment.

Endocrine effects of polycyclic musks: do we smell a rat?

B. van der Burg, A. Brouwer, E. Sonneveld, 2008, International journal of andrology.

Sample preparation method for the ER-CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts.

M. Lamoree, P. Leonards, A. Brouwer, 2007, The Science of the total environment.

Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits.

A. Brouwer, M. Denison, J. Koeman, 2003, Journal of agricultural and food chemistry.

Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachlorobiphenyl.

A. Brouwer, M. Denison, J. Aarts, 1993 .

Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.

Abraham Brouwer, Bart van der Burg, B. van der Burg, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Improving infant food safety by avoiding hazards of chemical mixture effects using novel integrated methods based on bioassays and analytical chemistry

R. Cariou, A. Brouwer, G. Dervilly, 2022, Global Pediatrics.

Paleotoxicity of petrogenic and pyrogenic hydrocarbon mixtures in sediment cores from the Athabasca oil sands region, Alberta (Canada).

R. Letcher, A. Brouwer, P. Thomas, 2021, Environmental pollution.

Bioanalytical Detection of Steroid Abuse in Sports Based on the Androgenic Activity Measurement

A. Brouwer, M. Fuentes-Ferrer, C. Fernández-Pérez, 2021, Chemosensors.

Associations between endocrine disrupting chemicals and equine metabolic syndrome phenotypes.

M. McCue, J. Mickelson, A. Brouwer, 2019, Chemosphere.

Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: relevant exposure measures for endocrine disruptors in epidemiologic studies?

R. Anzion, A. Brouwer, N. Roeleveld, 2011, Environment international.

Calux® reporter cell lines as sensitive bioassay for monitoring biological activity of various classes of steroid hormones revert the repressive effect of TCDD on the estrogen receptor

J. H. Jansen, N. Riteco, A. Brouwer, 2003 .

A Novel in Vivo Bioassay for (Xeno-)estrogens Using Transgenic Zebrafish

A. D. Vethaak, D. Živković, A. Brouwer, 2000 .

Degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) by fungi originating from Vietnam

R. V. van Spanning, A. Brouwer, J. Koekkoek, 2022, Biodegradation.

Toxic and biochemical effects of 3,3',4,4'-tetrachlorobiphenyl (CB-77) and clophen A50 on eider duckling (Somateria mollissima) in a semi-field experiment.

A. Brouwer, J. Koeman, A. Murk, 1994, Environmental pollution.

Effects of polyhalogenated aromatic hydrocarbons (PHAHs) on biochemical parameters in chicks of the common tern (Sterna hirundo)

A. Bosveld, A. Brouwer, A. Murk, 1994 .

Thyroxine and 3,3',5-triiodothyronine are glucuronidated in rat liver by different uridine diphosphate-glucuronyltransferases.

T. Visser, E. Krenning, M. Jong, 1991, Endocrinology.

Binding of a 3,3', 4,4'-tetrachlorobiphenyl (CB-77) metabolite to fetal transthyretin and effects on fetal thyroid hormone levels in mice.

A. Brouwer, P. Darnerud, E. Klasson-Wehler, 1996, Toxicology.

Hepatic retinoid levels in seven fish species (teleosts) from a tropical coastal lagoon receiving effluents from iron‐ore mining and processing

A. Brouwer, B. van Hattum, A. A. Pereira, 2012, Environmental toxicology and chemistry.

Chronic and reproductive toxicity of a mixture of 15 methylsulfonyl‐polychlorinated biphenyls and 3‐methylsulfonyl‐2,2‐bis‐(4‐chlorophenyl)‐1,1‐dichloroethene in mink (Mustela vison)

B. Brunström, A. Bergman, A. Brouwer, 1999 .

Dr‐Calux®: A High‐Throughput Screening Assay for the Detection of Dioxin and Dioxin‐Like Compounds in Food and Feed.

A. Brouwer, B. Burg, H. Besselink, 2013 .

OF DIOXIN-LIKE COMPOUNDS IN SEDIMENT SAMPLES FROM OSAKA BAY , JAPAN

S. Sakai, H. Takigami, A. Brouwer, 2011 .

Ah-receptor mediated luciferase expression: a tool for monitoring dioxin-like toxicity.

A. Brouwer, M. Denison, J. Aarts, 1993 .

Determination of the endocrine disrupting potency of hydroxylated PCB's and flame retardants with in vitro bioassays

A. Brouwer, J. Legler, T. Malmberg, 2002 .

Identification of 4-Hydroxyheptachlorostyrene in Polar Bear Plasma and Its Binding Affinity to Transthyretin: A Metabolite of Octachlorostyrene?

I. Meerts, R. Letcher, A. Brouwer, 2000 .

Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls.

T. Visser, A. Bergman, A. Brouwer, 1998, Chemico-biological interactions.

Transthyretin (prealbumin) binding of PCBS, a model for the mechanism of interference with vitamin A and thyroid hormone metabolism

W. Blaner, A. Brouwer, D. Goodman, 1986 .

Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development.

W. V. van Wieringen, A. Brouwer, J. de Boer, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Biomonitoring of estrogenic exposure and identification of responsible compounds in bream from Dutch surface waters

Juliette Legler, Peter M van Bodegom, Abraham Brouwer, 2007, Environmental toxicology and chemistry.

DR- and ER-CALUX assays as tools to direct toxicity identification and evaluation of endocrine disrupting chemicals

C. P. Swart, M. Lamoree, A. Brouwer, 2002 .

Polybrommated diphenyl ethers (PCDs) as Ah-receptor agonists and antagonists.

I. Meerts, G. Marsh, A. Bergman, 1998 .

beta-Naphthoflavone- and self-induced metabolism of 3,3',4,4'-tetrachlorobiphenyl in hepatic microsomes of the male, pregnant female and foetal rat.

P. van Bladeren, A. Brouwer, E. Wehler, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions.

H. van Toor, T. Visser, A. Brouwer, 1993, Endocrinology.

Effect-based detection of synthetic glucocorticoids in bovine urine

A. Brouwer, M. Pezzolato, E. Bozzetta, 2015, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

Correlating biodegradation kinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the dynamics of microbial communities originating from soil in Vietnam contaminated with herbicides and dioxins

R. V. van Spanning, A. Brouwer, W. Röling, 2022, Frontiers in Microbiology.

Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like PCBs in mouse hepatoma cells (Hepa1c1c7): involvement of the Ah receptor.

J. Simons, A. Brouwer, M. Denison, 1994, Toxicology and applied pharmacology.

Genome annotation and antimicrobial properties of Bacillus toyonensis VU‐DES13, isolated from the Folsomia candida gut

A. Brouwer, N. V. van Straalen, P. Hensbergen, 2019, Entomologia Experimentalis et Applicata.

Environmental occurrence, analysis, and toxicology of toxaphene compounds.

A. Brouwer, J. Boer, J. Klungsøyr, 1999, Environmental health perspectives.

Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs.

H. Glatt, D. Tibboel, C. Falany, 2000, Endocrinology.

Study on the mechanism of interference of 3,4,3',4'-tetrachlorobiphenyl with the plasma retinol-binding proteins in rodents.

W. Blaner, A. Brouwer, A. Kukler, 1988, Chemico-biological interactions.

Early decrease in retinoid levels in mice after exposure to low doses of polychlorinated biphenyls

A. Brouwer, K. J. Berg, 1983 .

Elucidating fungal Rigidoporus species FMD21 lignin-modifying enzyme genes and 2,3,7,8-tetrachlorodibenzo-p-dioxin degradation by laccase isozymes.

A. Brouwer, M. Smits, Tjalf E. de Boer, 2021, Enzyme and microbial technology.

In vitro inhibition of thyroid hormone sulfation by polychlorobiphenylols: isozyme specificity and inhibition kinetics.

T. Visser, A. Bergman, A. Brouwer, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Chromatographic analysis of endogenous retinoids in tissues and serum.

H. Nau, A. Brouwer, C. Schmidt, 2003, Analytical biochemistry.

Screening white-rot fungi for bioremediation potential of 2,3,7,8-tetrachlorodibenzo-p-dioxin

A. Brouwer, T. Janssens, Tjalf E. de Boer, 2019, Industrial Crops and Products.

Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls.

A. Brouwer, 1989, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Agaricus bisporus and its by-products as a source of valuable extracts and bioactive compounds.

B. van der Burg, A. Brouwer, A. Jiménez, 2019, Food chemistry.

A Functional Carbohydrate Degrading Enzyme Potentially Acquired by Horizontal Gene Transfer in the Genome of the Soil Invertebrate Folsomia candida

R. V. van Spanning, A. Brouwer, N. V. van Straalen, 2022, Genes.

Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs.

M. Longnecker, L. Birnbaum, S. Schantz, 1999, Environmental health perspectives.

Persistent alterations in regional brain glial fibrillary acidic protein and synaptophysin levels following pre- and postnatal polychlorinated biphenyl exposure.

A. Brouwer, D. Morse, W. Wesseling, 1996, Toxicology and applied pharmacology.

Long-term alterations in regional brain serotonin metabolism following maternal polychlorinated biphenyl exposure in the rat.

A. Brouwer, R. Seegal, D. Morse, 1996, Neurotoxicology.

Effects of 3,4,3',4'-tetrachlorobiphenyl on thyroid function and histology in marmoset monkeys.

A. Brouwer, K. J. van den Berg, C. Zurcher, 1988, Toxicology letters.

Species and Metabolic Pathways Involved in Bioremediation of Vietnamese Soil From Bien Hoa Airbase Contaminated With Herbicides

R. V. van Spanning, A. Brouwer, J. Parsons, 2021, Frontiers in Sustainable Cities.

Biochemical and physiological approaches in ecotoxicology.

A. Brouwer, J. Koeman, A. Murk, 1990 .

Maternal diet and dioxin-like activity, bulky DNA adducts and micronuclei in mother-newborns.

L. Knudsen, S. Loft, A. Brouwer, 2012, Mutation research.

Fetal, neonatal, and long-term alterations in hepatic retinoid levels following maternal polychlorinated biphenyl exposure in rats.

A. Brouwer, D. Morse, 1995, Toxicology and applied pharmacology.

Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings.

Nicholas J. Herkert, B. Coull, T. Zoeller, 2022, Chemosphere.

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin biodegradation by extracellular lignin-modifying enzymes from ligninolytic fungus.

A. Brouwer, K. Swart, Tjalf E. de Boer, 2021, Chemosphere.

Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals.

J. Giesy, A. Brouwer, M. Denison, 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Correlating Biodegradation Kinetics of 2,4-Dichlorophenoxyacetic Acid (2,4-D) and 2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T) to the Dynamics of Microbial Communities Originating From Soil in Vietnam Contaminated With Herbicides

R. V. van Spanning, A. Brouwer, J. Parsons, 2021, Frontiers in Sustainable Cities.

Toxicological risks to humans of toxaphene residues in fish

P. Leonards, A. Brouwer, J. Klungsøyr, 2012, Integrated environmental assessment and management.

Patterns of variability of retinol levels in a harbour porpoise population from an unpolluted environment

A. Brouwer, A. Aguilar, C. Lockyer, 1999 .

Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish.

Juliette Legler, Klaas Krab, Bart Pieterse, 2008, Environmental science & technology.

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat.

Abraham Brouwer, I. Meerts, A. Brouwer, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Screening methods for thyroid hormone disruptors.

K. Crofton, M. DeVito, R. Tyl, 1999, Environmental health perspectives.

Alterations in rat brain thyroid hormone status following pre- and postnatal exposure to polychlorinated biphenyls (Aroclor 1254).

J H Koeman, A. Brouwer, J. Koeman, 1996, Toxicology and applied pharmacology.

Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats.

T. Visser, A. Brouwer, J. Koeman, 1993, Toxicology and applied pharmacology.

Binding of a metabolite of 3,4,3',4'-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin.

A. Brouwer, K. J. van den Berg, K. Van den Berg, 1986, Toxicology and applied pharmacology.

Activation of the Ah receptor by tryptophan and tryptophan metabolites.

A. Brouwer, S. Seidel, M. Denison, 1998, Biochemistry.

Evolutionary ecology of beta‐lactam gene clusters in animals

A. Brouwer, K. Meusemann, T. Schol, 2017, Molecular ecology.

Distribution of the flame retardant tetrabromobisphenol A in pregnant and fetal rats and effect on thyroid hormone homeostasis

I. Meerts, A. Brouwer, J. Koeman, 1999 .

Are brominated flame retardants endocrine disruptors?

Juliette Legler, Abraham Brouwer, A. Brouwer, 2003, Environment international.

Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER‐CALUX reporter gene assay

Juliette Legler, A Dick Vethaak, Abraham Brouwer, 2002, Environmental toxicology and chemistry.

Effects of pentachlorophenol and hydroxylated polychlorinated biphenyls on thyroid hormone conjugation in a rat and a human hepatoma cell line.

T. Visser, A. Bergman, A. Brouwer, 1999, Toxicology in vitro : an international journal published in association with BIBRA.

Interactions of Persistent Environmental Organohalogens With the Thyroid Hormone System: Mechanisms and Possible Consequences for Animal and Human Health

T. Visser, A. Brouwer, A. Murk, 1998, Toxicology and industrial health.

In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.

Timo Hamers, Juliette Legler, Patrik L Andersson, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study.

P. van Bladeren, A. Brouwer, J. Koeman, 1993, Toxicology and applied pharmacology.

Synergistic Effect of 2,2 prime ,4,4 prime ,5,5 prime -Hexachlorobiphenyl and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on Hepatic Porphyrin Levels in the Rat

M. van den Berg, A. Brouwer, W. Seinen, 1996 .

Effects of iron-ore mining and processing on metal bioavailability in a tropical coastal lagoon

W. Salomons, B. Hattum, A. Brouwer, 2008 .

Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept.

J. Jacobson, S. Jacobson, S. Safe, 1992, European journal of pharmacology.

Effects of PCDDs, PCDFs and PCBs in common tern (sterna hirundo) breeding in estuarine and coastal colonies in the netherlands and belgium

A. Bosveld, A. Brouwer, A. Murk, 1995 .

The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays

L. Kamelia, A. Brouwer, P. Boogaard, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Environmental Occurrence, Analysis and Toxicology of Toxaphene Compounds

A. Brouwer, J. Boer, J. Klungsøyr, 1999 .

Structure dependent multiple interactions of polyhalogeneted aromatic hydrocarbons with the thyroid hormone system.

A. Brouwer, 1998 .

Role of biotransformation in PCB-induced alterations in vitamin A and thyroid hormone metabolism in laboratory and wildlife species.

A. Brouwer, 1991, Biochemical Society transactions.

In vitro metabolism of 3,3',4,4'-tetrachlorobiphenyl in relation to ethoxyresorufin-O-deethylase activity in liver microsomes of some wildlife species and rat.

A. Brouwer, A. Murk, D. Morse, 1994, European journal of pharmacology.

Developing potency factors for thyroid hormone disruption by PFASs using TTR-TRβ CALUX® bioassay and assessment of PFASs mixtures in technical products.

A. Brouwer, Jun Huang, R. Weber, 2021, Environment international.

Assessing Indoor Dust Interference with Human Nuclear Hormone Receptors in Cell-Based Luciferase Reporter Assays

T. Zoeller, A. Brouwer, K. Kannan, 2021, Environmental health perspectives.

Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants.

L S Birnbaum, J. Jacobson, S. Jacobson, 1995, European journal of pharmacology.

The risk of endometriosis and exposure to dioxins and polychlorinated biphenyls: a case-control study of infertile women.

J. Weyler, P. Schepens, A. Brouwer, 2001, Human reproduction.

Structure of human transthyretin complexed with bromophenols: a new mode of binding.

L. Johnson, I. Meerts, A. Bergman, 2000, Acta crystallographica. Section D, Biological crystallography.

Early and differential decrease in natural retinoid levels in C57BL/Rij and DBA/2 mice by 3,4,3',4'-tetrachlorobiphenyl.

A. Brouwer, K. J. Berg, K. Van den Berg, 1984, Toxicology and applied pharmacology.

Effects on thyroid hormone metabolism and depletion of lung vitamin A in rats by airborne particulate matter.

A. Brouwer, G. Alink, G. J. Schefferlie, 1993, Journal of toxicology and environmental health.

Health risks to infants from exposure to PCBs, PCDDs and PCDFs

M. Feeley, A. Brouwer, 2000, Food additives and contaminants.

Comparison of chemical-activated luciferase gene expression bioassay and gas chromatography for PCB determination in human serum and follicular fluid.

P. Schepens, A. Brouwer, A Brouwer, 2000, Environmental health perspectives.

Macrophages influence gap junctional intercellular communication between smooth muscle cells in a co-culture model.

A. Brouwer, J. Koeman, T. van der Wijk, 1998, Environmental toxicology and pharmacology.

Screening of molecular cell targets for carcinogenic heterocyclic aromatic amines by using CALUX® reporter gene assays

P. Steinberg, A. Brouwer, H. Besselink, 2017, Cell Biology and Toxicology.

Newborn infants diagnosed as neurologically abnormal with relation to PCB and dioxin exposure and their thyroid-hormone status.

C. Koopman‐Esseboom, A. Brouwer, N. Weisglas‐Kuperus, 1997, Developmental medicine and child neurology.

Investigation of the soil nematode community composition in a monoculture Robusta coffee plantation in Dak Lak, Vietnam

A. Brouwer, P. Q. Trinh, Tjalf E. de Boer, 2021, Global Ecology and Conservation.

Identification of estrogenic compounds in fish bile using bioassay-directed fractionation.

Juliette Legler, Abraham Brouwer, M. Lamoree, 2004, Environmental science & technology.

Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities.

Willem G Schoonen, Bart Pieterse, Abraham Brouwer, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Impaired cellular immune response in rats exposed perinatally to Baltic Sea herring oil or 2,3,7,8-TCDD

H. van Loveren, A. Osterhaus, A. Brouwer, 1997, Archives of Toxicology.

PAH-CALUX, an optimized bioassay for AhR-mediated hazard identification of polycyclic aromatic hydrocarbons (PAHs) as individual compounds and in complex mixtures.

B. van der Burg, A. Brouwer, A Brouwer, 2013, Environmental Science and Technology.

Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line.

A D Vethaak, B. van der Burg, A. Brouwer, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Validation and use of the CALUX-bioassay for the determination of dioxins and PCBs in bovine milk.

H. Kuiper, A. Brouwer, W. Traag, 1998, Food additives and contaminants.

Modulating effects of thyroid state on the induction of biotransformation enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

T. Visser, A. Brouwer, A. Schuur, 1998, Environmental toxicology and pharmacology.

Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity.

Abraham Brouwer, Bart van der Burg, Harrie Besselink, 2018, Reproductive toxicology.

Effects of retinoic acid on the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced differentiation of in vitro cultured human keratinocytes.

A. Brouwer, B. Blaauboer, J. Berkers, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Interference between Progesterone and Dioxin Signal Transduction Pathways

B. van der Burg, A. Brouwer, P. T. van der Saag, 1998, The Journal of Biological Chemistry.

Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor.

Abraham Brouwer, Bart van der Burg, O. Meijer, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort.

B. van der Burg, A. Brouwer, E. de Rijke, 2020, Environment international.

Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs.

J. Kleinjans, L. Knudsen, S. Loft, 2010, Environment international.

Anti-androgenic compounds in breast milk and cryptorchidism among Norwegian boys in the HUMIS birth cohort.

T. K. Jensen, B. van der Burg, A. Brouwer, 2021, Science of the Total Environment.

SIMONI (Smart Integrated Monitoring) as a novel bioanalytical strategy for water quality assessment: Part I–model design and effect‐based trigger values

Ron van der Oost, Giulia Sileno, Maria Suárez-Muñoz, 2017, Environmental toxicology and chemistry.

Prenatal exposure of rats to hydroxylated PCBs and some brominated flame retardants

A. Brouwer, A. Gutleb, M. Velzen, 2006 .

In vitro screening of the endocrine disrupting potency of brominated flame retardants and their metabolites

T. Hamers, A. Brouwer, E. Sonneveld, 2004 .

Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays.

Bart Van der Burg, Abraham Brouwer, Minne B Heringa, 2008, Environmental science & technology.

S. Sakai, H. Takigami, Shin Takahashi, 2013, Environmental science & technology.

Thyroxine binding to transthyretin Met 119

A. Brouwer, A. Damas, M. R. Almeida, 1997, Endocrine.

Altered thyroxine binding to amyloidogenic and non-amyloidogenic transthyretin variants: TTR Met 119 and TTR Pro 55

A. Brouwer, M. R. Almeida, M. Saraiva, 1996, Neuromuscular Disorders.

Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats.

I. Meerts, S. Hoving, A. Brouwer, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Occurrence of endophytic bacteria in Vietnamese Robusta coffee roots and their effects on plant parasitic nematodes

A. Brouwer, P. Q. Trinh, N. Pham, 2019, Symbiosis.

Interaction of polybrominated biphenyls ether metabolites (PBDE-OH) with human transthyretin in vitro.

Eva Jakobsson, Åke Bergman, Abraham Brouwer, 1998 .

In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins

A. Brouwer, W. Vetter, H. Besselink, 2021, Archives of Toxicology.

A low volume method for the analysis of dioxins and dioxin-like compounds in serum and whole blood using BDS¿ Dr Calux® Bioassay

A. Brouwer, E. Sonneveld, B. Burg, 2004 .

Subchronic toxicity and reproduction effects of tri-n-butyltin oxide in Japanese quail

A. Brouwer, J. Koeman, I. C. Enninga, 1992, Archives of environmental contamination and toxicology.

Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells.

Kazunori Hosoe, Abraham Brouwer, Shin-Ichi Sakai, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Effects of subchronic exposure to complex mixtures of dioxin-like and non-dioxin-like polyhalogenated aromatic compounds on thyroid hormone and vitamin A levels in female Sprague-Dawley rats.

A. Brouwer, I. Lutke-Schipholt, B. Spenkelink, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Post-mortem stability of blubber DLCs, PCB and tDDT in by-caught harbour porpoises (Phocoena phocoena).

P. Reijnders, A. Brouwer, A. Read, 2007, Marine pollution bulletin.

Application of the chemical-activated luciferase expression (CALUX) bioassays for quantification of dioxin-like compounds in small samples of human milk and blood plasma.

A. Brouwer, A. Murk, B. Blankvoort, 1996 .

Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays.

Juliette Legler, A Dick Vethaak, Abraham Brouwer, 2002, The Science of the total environment.

The effect of 3,3′,4,4′-tetrachlorobiphenyl and clophen A50 on the hepatic monooxygenase system of Eider Ducklings (Somateria mollissima) with indications for structure-related biotransformation of CB congeners

A. Brouwer, J. Koeman, A. Murk, 1992 .

Detection of anabolic androgenic steroid abuse in doping control using mammalian reporter gene bioassays.

Saskia S Sterk, Abraham Brouwer, Bart van der Burg, 2009, Analytica chimica acta.

Effects of outdoor and indoor airborne particulate matter on thyroid hormone and vitamin A metabolism.

A. Brouwer, G. Alink, G. Heussen, 1994, Toxicology letters.

Peregrine falcon egg pollutants

H. Köhler, A. Brouwer, R. Malisch, 2016 .

Peregrine falcon egg pollutants: Mirror Stockholm POPs list including methylmercury

H. Köhler, A. Brouwer, R. Malisch, 2016 .

Identification of major dioxin-like compounds and androgen receptor antagonist in acid-treated tissue extracts of high trophic-level animals.

Marja Lamoree, Tomohiko Isobe, Shinsuke Tanabe, 2011, Environmental science & technology.

Global survey of dioxin- and thyroid hormone-like activities in consumer products and toys

A. Brouwer, G. Jensen, Y. Ismawati, 2023, Environment International.

Formation of polybrominated dibenzofurans (PBDFs) after heating of a salmon sample spiked with decabromodiphenyl ether (BDE-209)

A. Brouwer, W. Vetter, Paul Bendig, 2015, Environmental Science and Pollution Research.

Controlling persistent organic pollutants-what next?

D. Mackay, A. Brouwer, C. Gough, 1998, Environmental toxicology and pharmacology.

Effects of prenatal exposure to hydroxylated PCB metabolites and some brominated flame retardants on the development of rats

A. Brouwer, A. Gutleb, M. Velzen, 2004 .

Structure-dependent, competitive interaction of hydroxy-polychlorobiphenyls, -dibenzo-p-dioxins and -dibenzofurans with human transthyretin.

S. Safe, A. Brouwer, A. Brouwer, 1993, Chemico-biological interactions.

Biodegradation of Fipronil: Transformation Products, Microbial Characterisation and Toxicity Assessment

A. Brouwer, B. V. van Vugt-Lussenburg, A. Langenhoff, 2021, Water, Air, & Soil Pollution.

Effect-directed analysis and chemical identification of agonists of peroxisome proliferator-activated receptors in white button mushroom.

B. van der Burg, A. Brouwer, K. Swart, 2020, Food & function.

Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.

R. Houtman, A. Brouwer, I. Rietjens, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.

T. Hamers, A. Brouwer, E. Sonneveld, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters.

Abraham Brouwer, Dick Tibboel, Walter Meinl, 2002, The Journal of clinical endocrinology and metabolism.

Synergistic effect of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat.

M. van den Berg, A. Brouwer, W. Seinen, 1996, Environmental health perspectives.

Development of Calux bioassay-based systems as instruments to detect hormones and contaminants

A. Brouwer, E. Sonneveld, B. Burg, 2006 .

Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses.

Juliette Legler, Abraham Brouwer, Eric Jover, 2006, Chemosphere.

Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption

Timo Hamers, Juliette Legler, Abraham Brouwer, 2004, Environmental toxicology and chemistry.

Toxic potency of 2,3,3',4,4',5-hexachlorobiphenyl relative to and in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin in a subchronic feeding study in the rat.

M. van den Berg, A. Brouwer, A. Brouwer, 1994, Toxicology and applied pharmacology.

Biological validation of a sample preparation method for ER-CALUX bioanalysis of estrogenic activity in sediment using mixtures of xeno-estrogens.

M. Lamoree, P. Leonards, A. Brouwer, 2006, Environmental science & technology.

Development of improved DR-CALUX bioassay for sensitive measurement of aryl hydrocarbon receptor activating compounds

J. H. Jansen, A. Brouwer, E. Sonneveld, 2002 .