D. Abernethy

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Abciximab Pharmacodynamic Model with Neural Networks used to Integrate Sources of Patient Variability

M. Urquidi-Macdonald, D. Mager, M. Mascelli, 2004, Clinical pharmacology and therapeutics.

Diazepam kinetics in relation to age and sex.

D. Greenblatt, H. Ochs, D. Abernethy, 1981, Pharmacology.

Effect of Age, Gender, and Obesity on Midazolam Kinetics

D. Greenblatt, J. Harmatz, R. Shader, 1984, Anesthesiology.

Amlodipine in elderly hypertensive patients: pharmacokinetics and pharmacodynamics.

D. Abernethy, J. Gutkowska, M. Lambert, 1988, Journal of cardiovascular pharmacology.

Consensus Recommendations for Systematic Evaluation of Drug–Drug Interaction Evidence for Clinical Decision Support

Michael A. Wittie, D. Malone, A. Grizzle, 2015, Drug Safety.

Kinetics, brain uptake, and receptor binding characteristics of flurazepam and its metabolites

S. Paul, D. Greenblatt, R. Shader, 1988, Psychopharmacology.

Liver injury due to verapamil.

J. Burgunder, D. Abernethy, B. Lauterburg, 1988, Hepato-gastroenterology.

Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

Shiew-Mei Huang, Yuichi Sugiyama, Ping Zhao, 2012, Journal of clinical pharmacology.

Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology

Samik Ghosh, Hiroaki Kitano, Yukio Homma, 2015, npj Systems Biology and Applications.

Integration of Diverse Data Sources for Prediction of Adverse Drug Events

D R Abernethy, D. Abernethy, J. Bai, 2011, Clinical pharmacology and therapeutics.

Pharmacogenomics and adverse drug reactions.

Shiew-Mei Huang, Darrell R Abernethy, Issam Zineh, 2010, Personalized medicine.

Systems pharmacology to predict drug toxicity: integration across levels of biological organization.

Darrell R Abernethy, Jane P F Bai, D. Abernethy, 2013, Annual review of pharmacology and toxicology.

Linking MedDRA®-Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors

Darrell R. Abernethy, Yongqun He, Sirarat Sarntivijai, 2016, Drug Safety.

Ca2+ sensors of L‐type Ca2+ channel

H. Kahr, C. Romanin, D. Abernethy, 2000, FEBS letters.

Differential Role of the α1C Subunit Tails in Regulation of the Cav1.2 Channel by Membrane Potential, β Subunits, and Ca2+ Ions*

E. Lakatta, D. Abernethy, V. Maltsev, 2005, Journal of Biological Chemistry.

New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel.

D. Abernethy, E. Kobrinsky, N. Soldatov, 2004, The Journal of biological chemistry.

Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients. Altered electrocardiographic and hypotensive responses.

D. Abernethy, J. Schwartz, E. Todd, 1986, Annals of internal medicine.

Physiologic Changes in Old Age: Relation to Altered Drug Disposition

D. Greenblatt, R. Shader, D. Abernethy, 1982, Journal of the American Geriatrics Society.

Use of Biomedical Ontologies for Integration of Biological Knowledge for Learning and Prediction of Adverse Drug Reactions

Sirarat Sarntivijai, Darrell R Abernethy, D. Abernethy, 2017, Gene regulation and systems biology.

An overview of the pharmacokinetics and pharmacodynamics of amlodipine in elderly persons with systemic hypertension.

D. Abernethy, 1994, The American journal of cardiology.

Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation

D. Abernethy, N. Ford, J. Barbey, 2001, Clinical pharmacology and therapeutics.

Logic-Based and Cellular Pharmacodynamic Modeling of Bortezomib Responses in U266 Human Myeloma Cells

Meric A. Ovacik, D. Mager, D. Abernethy, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Application of Systems Pharmacology to Explore Mechanisms of Hepatotoxicity

D. Abernethy, J. Shon, 2014, Clinical pharmacology and therapeutics.

Improving Therapeutics to Better Care for Older Adults and the Young: Report From the American College of Clinical Pharmacology Workshop

T. Eissing, A. Golden, D. Abernethy, 2018, Journal of clinical pharmacology.

Cerebrospinal fluid uptake and peripheral distribution of centrally acting drugs: Relation to lipid solubility

D. Greenblatt, H. Ochs, D. Abernethy, 1985, The Journal of pharmacy and pharmacology.

Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium.

P. O’Neill, L. Michael, D. Abernethy, 1987, The American journal of physiology.

High-performance liquid chromatographic determination of acetaminophen in plasma: single-dose pharmacokinetic studies.

D. Greenblatt, D. Abernethy, M. Divoll, 1981, Journal of chromatography.

Total Protein Methods and Their Potential Utility to Reduce the Risk of Food Protein Adulteration.

D. Abernethy, Jeffrey C Moore, M. Lipp, 2010, Comprehensive reviews in food science and food safety.

Effect of angiotensin-converting enzyme insertion/deletion polymorphism DD genotype on high-frequency heart rate variability in African Americans.

Marcellus M. Merritt, A. Zonderman, M. Evans, 2003, The American journal of cardiology.

Aging is associated with endothelial dysfunction in the human forearm vasculature.

N. S. Andrawis, D. Abernethy, N. Andrawis, 2000, Journal of the American Geriatrics Society.

Labetalol in the Treatment of Hypertension in Elderly and Younger Patients

D. Abernethy, J. Plachetka, P. Bartos, 1987, Journal of clinical pharmacology.

PHARMACOLOGY ACROSS THE AGING CONTINUUM

N. Gronich, D. Abernethy, 2009 .

Physiological pharmacokinetics and pharmacodynamics of (+/-)-verapamil in female rats.

D. Abernethy, E. Todd, 1987, Biopharmaceutics & drug disposition.

Comparison in young and elderly patients of pharmacodynamics and disposition of labetalol in systemic hypertension.

D. Abernethy, J. Schwartz, E. Todd, 1987, The American journal of cardiology.

Effects of desmethyldiazepam on diazepam kinetics: A study of effects of a metabolite on parent drug disposition

D. Greenblatt, D. Abernethy, 1981, Clinical pharmacology and therapeutics.

Aging: Its Influence on Drug Disposition and Effect

D. Abernethy, 2000 .

Aging effects on drug disposition and effect.

D. Abernethy, 1999, Geriatric nephrology and urology.

Pharmacokinetic Investigations in Elderly Patients Clinical and Ethical Considerations

D. Abernethy, D. Azarnoff, Daniel L. Azarnoff, 1990, Clinical pharmacokinetics.

JPET # 113183 PiP 2 Running title : Wavelet and Fourier Transforms in Pharmacodynamics

D. Mager, D. Abernethy, 2006 .

Stereoselective halofantrine disposition and effect: concentration-related QTc prolongation.

J. Pezzullo, D. Abernethy, D. Wesche, 2001, British journal of clinical pharmacology.

JPET #224766 1 Logic-based and Cellular Pharmacodynamic Modeling of Bortezomib Responses in U266 Human Myeloma Cells

Meric A. Ovacik, D. Mager, D. Abernethy, 2015 .

Effects of endothelial nitric oxide synthase gene polymorphisms on platelet function, nitric oxide release, and interactions with estradiol.

J. Freedman, J. Tanus-Santos, J. Pezzullo, 2002, Pharmacogenetics.

Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.

D. Mager, D. Fitzgerald, D. Abernethy, 2005, Journal of pharmaceutical sciences.

Cimetidine disposition in obesity.

D. Greenblatt, R. Gugler, D. Abernethy, 1984, The American journal of gastroenterology.

Alterations in drug distribution and clearance due to obesity.

D. Greenblatt, J. Harmatz, R. Shader, 1981, The Journal of pharmacology and experimental therapeutics.

Digoxin disposition in obesity: clinical pharmacokinetic investigation.

D. Greenblatt, D. Abernethy, T. Smith, 1981, American heart journal.

Phenytoin disposition in obesity. Determination of loading dose.

D. Greenblatt, D. Abernethy, 1985, Archives of neurology.

Lidocaine disposition in obesity.

D. Greenblatt, D. Abernethy, 1984, The American journal of cardiology.

Endothelin-1 induces an increase in total protein synthesis and expression of the smooth muscle alpha-actin gene in vascular smooth muscle cells.

D. Abernethy, N. Andrawis, E. Wang, 1996, Life sciences.

Increased cimetidine clearance in burn patients.

D. Greenblatt, D. Abernethy, J. Martyn, 1985, JAMA.

Antipyrine kinetics in the elderly: prediction of age-related changes in benzodiazepine oxidizing capacity.

D. Greenblatt, J. Harmatz, R. Shader, 1982, The Journal of pharmacology and experimental therapeutics.

Exendin-4 Pharmacodynamics: Insights from the Hyperglycemic Clamp Technique

D. Mager, D. Abernethy, J. Egan, 2004, Journal of Pharmacology and Experimental Therapeutics.

P-Glycoprotein in clinical cardiology.

D. Abernethy, R. Woosley, I. Rodriguez, 1999, Circulation.

β2‐adrenoceptor agonists and antagonists and risk of Parkinson's disease

N. Gronich, I. Lavi, G. Rennert, 2018, Movement disorders : official journal of the Movement Disorder Society.

Doxepin-cimetidine interaction: increased doxepin bioavailability during cimetidine treatment.

D. Abernethy, E. Todd, 1986, Journal of clinical psychopharmacology.

Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin.

D. Greenblatt, J. Harmatz, R. Shader, 1986, Arthritis and rheumatism.

Acetaminophen kinetics in the elderly

D. Greenblatt, D. Abernethy, M. Divoll, 1982, Clinical pharmacology and therapeutics.

Obesity, sex, and acetaminophen disposition

D. Greenblatt, D. Abernethy, M. Divoll, 1982, Clinical pharmacology and therapeutics.

Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition.

D. Greenblatt, J. Harmatz, R. Shader, 1989, Pharmacology.

Absorption and disposition of ibuprofen in the elderly.

D. Greenblatt, J. Harmatz, R. Shader, 1984, Arthritis and rheumatism.

Plasma adenosine deaminase2: a marker for human immunodeficiency virus infection.

D. Abernethy, K. Mayer, N. Kouttab, 1991, Journal of acquired immune deficiency syndromes.

Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension.

S. Oparil, D. Abernethy, I. Kobrin, 1997, American journal of hypertension.

Age Does Not Alter Acetaminophen Absorption

D. Greenblatt, D. Abernethy, M. Divoll, 1982, Journal of the American Geriatrics Society.

Cimetidine Impairs Clearance of Antipyrine and Desmethyldiazepam in the Elderly

D. Greenblatt, R. Shader, D. Abernethy, 1982, Journal of the American Geriatrics Society.

Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension.

D. Abernethy, J. Schwartz, 1987, The American journal of cardiology.

Pharmacologic and pharmacokinetic profile of mibefradil, a T- and L-type calcium channel antagonist.

D. Abernethy, 1997, The American journal of cardiology.

Angiotensin II Regulates Human Vascular Smooth Muscle α-Actin Gene Expression

D. Abernethy, N. Andrawis, E. Ruley, 1993 .

Angiotensin II regulates human vascular smooth muscle alpha-actin gene expression.

D. Abernethy, N. Andrawis, E. Ruley, 1993, Biochemical and biophysical research communications.

Impaired endothelial‐dependent forearm vascular relaxation in black Americans

D. Abernethy, Drew S. Jones, N. Andrawis, 1999, Clinical pharmacology and therapeutics.

Verapamil decreases lymphocyte protein kinase C activity in humans

D. Abernethy, P. DePetrillo, I. Wainer, 1994, Clinical pharmacology and therapeutics.

Research Challenges, New Drug Development, Preclinical and Clinical Trials in the Ageing Population

D. Abernethy, 1990, Drug safety.

Hypothyroidism Is a Risk Factor for New-Onset Diabetes: A Cohort Study

N. Gronich, I. Lavi, G. Rennert, 2015, Diabetes Care.

Nitric oxide inhibits Oct-1 DNA binding activity in cultured vascular smooth muscle cells.

D. Abernethy, X. Liu, N. Andrawis, 1998, Life sciences.

New strategies in cardiovascular disease management: Summary of round table discussion

J. Ménard, J. Cohn, D. Abernethy, 1997 .

Lorazepam and oxazepam kinetics in women on low‐dose oral contraceptives

D. Greenblatt, J. Harmatz, R. Shader, 1983, Clinical pharmacology and therapeutics.

Impairment of antipyrine metabolism by low‐dose oral contraceptive steroids

D. Greenblatt, D. Abernethy, 1981, Clinical pharmacology and therapeutics.

Pharmacodynamics of abciximab during angioplasty: Comparison to healthy subjects

J. Pezzullo, M. Mascelli, B. Frederick, 2002, Clinical pharmacology and therapeutics.

Variability in Human Cardiovascular Pharmacodynamics

D. Abernethy, 1991 .

Development of Memory‐Enhancing Agents in the Treatment of Alzheimer's Disease

D. Abernethy, 1987, Journal of the American Geriatrics Society.

Pharmacokinetic studies on Ro 15-1788, a benzodiazepine receptor ligand, in the brain of the rat

S. File, D. Greenblatt, R. Lister, 1984, Brain Research.

Pharmacological properties of combination therapies for hypertension.

D. Abernethy, Darrell R. Abernethy, 1997, American journal of hypertension.

Forearm vascular α1‐adrenergic blockade by verapamil

D. Abernethy, L. Winterbottom, 1990 .

Calcium antagonists block angiotensin II-mediated vasoconstriction in humans: comparison with their effect on phenylephrine-induced vasoconstriction.

D. Abernethy, N. Craft, N. Andrawis, 1992, The Journal of pharmacology and experimental therapeutics.

Verapamil metabolite exposure in older and younger men during steady-state oral verapamil administration.

D. Abernethy, I. Wainer, A. Anacleto, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacodynamic profile of short-term readministration of abciximab in healthy subjects.

R. Jordan, J. Pezzullo, M. Mascelli, 2002, American heart journal.

Quantitative and Systems Pharmacology in the Post-genomic Era : New Approaches to Discovering Drugs and Understanding Therapeutic

Ravi Iyengar, Darrell R. Abernethy, Paolo Vicini, 2011 .

Methodological Issues in the Design of Paediatric Pharmacokinetic Studies

D. Abernethy, Jian Wang, P. Jadhav, 2012, Pharmaceutical Medicine.

The Pharmacokinetics of Midazolam in Chronic Renal Failure Patients

L. Smith, D. Greenblatt, J. Reves, 1983, Anesthesiology.

New Molecular Determinant for Inactivation of the Human L-Type α1C Ca2+ Channel

M. Morad, D. Abernethy, B. Albanna, 2000, The Journal of Membrane Biology.

Cardiovascular Effects of and Interaction Between Calcium Blocking Drugs and Anesthetics in Chronically Instrumented Dogs. IV. Chronically Administered Oral Verapamil and Halothane, Enflurane, and Isoflurane

C. Hartley, J. Chelly, D. Abernethy, 1987, Anesthesiology.

Acute and chronic studies of diltiazem in elderly versus young hypertensive patients.

D. Abernethy, S. Montamat, 1987, The American journal of cardiology.

Imipramine disposition in users of oral contraceptive steroids

D. Greenblatt, R. Shader, D. Abernethy, 1984, Clinical pharmacology and therapeutics.

Pharmacokinetics and Clinical Effectiveness of Methylphenidate

D. Abernethy, J. Cross, H. Kimko, 1999, Clinical pharmacokinetics.

Local angiotensin‐converting enzyme inhibition blunts endothelin‐1–induced increase in forearm vascular resistance

N. Laurie, D. Abernethy, N. Andrawis, 1995, Clinical pharmacology and therapeutics.

Endothelin‐I—mediated vasoconstriction: Specific blockade by verapamil

D. Abernethy, N. Andrawis, J. Gilligan, 1992, Clinical pharmacology and therapeutics.

Pharmacokinetics of alprazolam.

D. Greenblatt, R. Shader, D. Abernethy, 1983, The Journal of clinical psychiatry.

Glutathione is a cofactor for H2O2-mediated stimulation of Ca2+-induced Ca2+ release in cardiac myocytes.

M. Morad, D. Abernethy, L. Cleemann, 1998, Free radical biology & medicine.

Differential effect of cimetidine on drug oxidation (antipyrine and diazepam) vs. conjugation (acetaminophen and lorazepam): prevention of acetaminophen toxicity by cimetidine.

D. Greenblatt, R. Shader, D. Abernethy, 1983, The Journal of pharmacology and experimental therapeutics.

Effect of calcium antagonists on RNA synthesis of NIH 3T3 cells.

D. Abernethy, N. Andrawis, 1993, The American journal of the medical sciences.

Is Volume of Distribution at Steady State a Meaningful Kinetic Variable?

D. Greenblatt, D. Abernethy, M. Divoll, 1983, Journal of clinical pharmacology.

Interaction of Cimetidine with Oxazepam, Lorazepam, and Flurazepam

D. Greenblatt, R. Shader, D. Abernethy, 1984, Journal of clinical pharmacology.

Issue Information

D. Abernethy, A. Lawrence, 2020, Decis. Sci..

Calcium antagonists in geriatric patients: Diltiazem in elderly persons with hypertension

D. Abernethy, S. Montamat, Stephen C Montamat, 1989, Clinical pharmacology and therapeutics.

Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction*

D. Abernethy, J. Rifkind, E. Nagababu, 2003, Journal of Biological Chemistry.

Selective inhibition of warfarin metabolism by diltiazem in humans.

D. Abernethy, L. Kaminsky, T. H. Dickinson, 1991, The Journal of pharmacology and experimental therapeutics.

Pharmacokinetics of Drugs in Obesity

D. Greenblatt, D. Abernethy, 1982, Clinical pharmacokinetics.

Reduced clearance of triazolam in old age: relation to antipyrine oxidizing capacity.

D. Greenblatt, R. Shader, D. Abernethy, 1983, British journal of clinical pharmacology.

N-monodesmethyldiltiazem is the predominant metabolite of diltiazem in the plasma of young and elderly hypertensives.

D. Abernethy, S. Montamat, 1987, British journal of clinical pharmacology.

OPTIMIZED PHARMACOKINETIC AND PHARMACODYNAMIC PROFILES IN CARDIOVASCULAR DISEASE THERAPY

D. Abernethy, 1997 .

Hypothyroidism Is a Risk Factor for New-Onset Diabetes Mellitus: A Cohort Study

N. Gronich, I. Lavi, G. Rennert, 2015 .

The Influence of Obesity on the Pharmacokinetics of Oral Alprazolam and Triazolam

D. Greenblatt, R. Shader, D. Abernethy, 1984, Clinical pharmacokinetics.

Pharmacokinetics and pharmacodynamics of amlodipine.

D. Abernethy, 1992, Cardiology.

Altered pharmacodynamics of cardiovascular drugs and their relation to altered pharmacokinetics in elderly patients.

D. Abernethy, 1990, Clinics in geriatric medicine.

Diltiazem and captopril alone or in combination for treatment of mild to moderate systemic hypertension.

D. Abernethy, D. DiPette, R. Zusman, 1988, The American journal of cardiology.

Pharmacokinetic properties of benzodiazepine hypnotics.

D. Greenblatt, J. Harmatz, R. Shader, 1983, Journal of clinical psychopharmacology.

Enantioselective separation and online affinity chromatographic characterization of R,R- and S,S-fenoterol.

D. Abernethy, C. Bertucci, I. Wainer, 2006, Chirality.

Pediatric Dose Selection

D. Abernethy, G. Burckart, 2010, Clinical pharmacology and therapeutics.

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

Darrell R. Abernethy, Franz Hofmann, Michael Spedding, 2003, Pharmacological Reviews.

The pharmacokinetic profile of amlodipine.

D. Abernethy, 1989, American heart journal.

Current Status of Benzodiazepines

D. Greenblatt, R. Shader, D. Abernethy, 1983 .

Metal Impurities in Food and Drugs

D. Abernethy, A. Destefano, Roger L. Williams, 2010, Pharmaceutical Research.

The synthesis of 2,4-diketo-5-phenyl- 5 -7-oxa-1,3-diazabicyclo(4.4.0)decane and 2,4-diketo-3-phenyl- 5 -7-oxa-1,5-diazabicyclo(4.4.0)decane.

D. Abernethy, J. Ayres, P. Wirth, 1972, The Journal of organic chemistry.

Revision of instructions to authors for pharmacology research and perspectives: enhancing the quality and transparency of published work

Michael J Curtis, Darrell R Abernethy, D. Abernethy, 2015, Pharmacology research & perspectives.

Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor.

D. Abernethy, I. Wainer, R. Xiao, 2007, Journal of medicinal chemistry.

Diazepam kinetics in patients with renal insufficiency or hyperthyroidism.

D. Greenblatt, H. Ochs, D. Abernethy, 1981, British journal of clinical pharmacology.

In vitro inhibition of rat liver cholest-5en-3β-ol (cholesterol) biosynthesis by non-mercurial sulfhydryl reagents

D. Abernethy, C. Hignite, D. Azarnoff, 1976, Steroids.

Pharmacologic properties of acebutolol: relationship of hydrophilicity to central nervous system penetration.

D. Greenblatt, D. Abernethy, R. Arendt, 1985, American heart journal.

Benzodiazepine hypnotic metabolism: drug interactions and clinical implications

D. Greenblatt, R. Shader, D. Abernethy, 1986, Acta psychiatrica Scandinavica. Supplementum.

Methodological Concerns for Clinical Trials in Geriatrics

D. Abernethy, 1986 .

Clinical Pharmacokinetics of the Newer Benzodiazepines

D. Greenblatt, R. Shader, H. Ochs, 1983, Clinical pharmacokinetics.

Effect of Obesity on the Pharmacokinetics of Drugs in Humans

Darrell R. Abernethy, David J. Greenblatt, D. Greenblatt, 2010, Clinical pharmacokinetics.

Probenecid impairment of acetaminophen and lorazepam clearance: direct inhibition of ether glucuronide formation.

D. Greenblatt, R. Shader, D. Abernethy, 1985, The Journal of pharmacology and experimental therapeutics.

High-performance liquid chromatographic determination of diltiazem and its major metabolites, N-monodemethyldiltiazem and desacetyldiltiazem, in plasma.

D. Abernethy, J. Mitchell, S. Montamat, 1987, Journal of chromatography.

Structure-activity relationship of ligands of human plasma adenosine deaminase2.

D. Abernethy, J. G. Niedzwicki, 1991, Biochemical pharmacology.

Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome

D. Abernethy, K. Burkhart, David Jackson, 2015, Journal of Medical Toxicology.

Minoxidil analysis in human plasma using high-performance liquid chromatography with electrochemical detection. Application to pharmacokinetic studies.

D. Abernethy, G. Carrum, C. Wright, 1986, Journal of chromatography.

Role of Systems Modeling in Regulatory Drug Approval

Shiew-Mei Huang, Darrell R. Abernethy, Vikram Sinha, 2016 .

The utility of modeling and simulation in drug development and regulatory review.

Shiew-Mei Huang, Ping Zhao, Yaning Wang, 2013, Journal of pharmaceutical sciences.

Drug Disposition in Obese Humans

D. Greenblatt, D. Abernethy, 1986, Clinical pharmacokinetics.

Caffeine disposition in obesity.

D. Abernethy, J. Schwartz, E. Todd, 1985, British journal of clinical pharmacology.

Differential effects of isoniazid and oral contraceptive steroids on antipyrine oxidation and acetaminophen conjugation.

D. Greenblatt, H. Ochs, D. Abernethy, 1984, Pharmacology.

Increased Metabolic Clearance of Acetaminophen with Oral Contraceptive Use

D. Greenblatt, H. Ochs, D. Abernethy, 1982, Obstetrics and gynecology.

Impairment of caffeine clearance by chronic use of low-dose oestrogen-containing oral contraceptives

D. Abernethy, E. Todd, 2004, European Journal of Clinical Pharmacology.

Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids.

D. Greenblatt, R. Shader, H. Ochs, 1982, The New England journal of medicine.

Drug burden index score and functional decline in older people.

E. Simonsick, D. Bauer, T. Harris, 2009, The American journal of medicine.

HPLC-atmospheric pressure chemical ionization mass spectrometric method for enantioselective determination of R,S-propranolol and R,S-hyoscyamine in human plasma.

N. Gronich, D. Mager, D. Abernethy, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A drug burden index to define the functional burden of medications in older people.

S. Rubin, J. Hanlon, E. Simonsick, 2007, Archives of internal medicine.

Effects of amlodipine, a long‐acting dihydropyridine calcium antagonist in aging hypertension: Pharmacodynamics in relation to disposition

D. Abernethy, J. Gutkowska, L. Winterbottom, 1990, Clinical pharmacology and therapeutics.

Diphenhydramine determination in human plasma by gas-liquid chromatography using nitrogen-phosphorus detection: application to single low-dose pharmacokinetic studies.

D. Greenblatt, D. Abernethy, 1983, Journal of pharmaceutical sciences.

Close correlation of acetaminophen clearance with that of conjugated benzodiazepines but not oxidized benzodiazepines

D. Greenblatt, R. Shader, D. Abernethy, 2004, European Journal of Clinical Pharmacology.

Simultaneous determination of lidocaine and its deethylated metabolites using gas-liquid chromatography with nitrogen-phosphorus detection.

D. Greenblatt, D. Abernethy, D. M. Benjamin, 1984, Journal of chromatography.

Dose‐Independent Pharmacokinetics of Intravenous Lidocaine in Humans

D. Greenblatt, H. Ochs, D. Abernethy, 1983, Journal of clinical pharmacology.

Benzodiazepine drug-drug interactions commonly occurring in clinical practice.

D. Greenblatt, R. Shader, H. Ochs, 1984, Current medical research and opinion.

Absolute and relative bioavailability of oral acetaminophen preparations.

D R Abernethy, D J Greenblatt, D. Greenblatt, 1983, Journal of pharmaceutical sciences.

Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen.

D. Greenblatt, R. Shader, D. Abernethy, 1983, The Journal of laboratory and clinical medicine.

Effect of Food on Acetaminophen Absorption in Young and Elderly Subjects

D. Greenblatt, D. Abernethy, M. Divoll, 1982, Journal of clinical pharmacology.

Verapamil and norverapamil determination in human plasma by gas-liquid chromatography using nitrogen-phosphorus detection: application to single-dose pharmacokinetic studies.

D. Abernethy, J. Mitchell, E. Todd, 1984, Pharmacology.

Imipramine-cimetidine interaction: impairment of clearance and enhanced absolute bioavailability.

D. Greenblatt, R. Shader, D. Abernethy, 1984, The Journal of pharmacology and experimental therapeutics.

Lidocaine determination in human plasma with application to single low-dose pharmacokinetic studies.

D. Greenblatt, H. Ochs, D. Abernethy, 1982, Journal of chromatography.

Elevated blood pressure in spontaneously hypertensive rats consuming a high sucrose diet is associated with elevated angiotensin II and is reversed by vanadium

D. Abernethy, H. Preuss, S. Jarrell, 1997, Journal of hypertension.

Bidirectional interactions between indomethacin and the murine intestinal microbiota

Kyle Bittinger, Darrell R Abernethy, Frederic D Bushman, 2015, eLife.

Pharmacological Mechanism‐Based Drug Safety Assessment and Prediction

LJ Lesko, J. Woodcock, D. Abernethy, 2011, Clinical pharmacology and therapeutics.

Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats

M. Mattson, D. Mager, D. Abernethy, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

In vitro quantitation of benzodiazepine lipophilicity: relation to in vivo distribution.

D. Greenblatt, R. Shader, E. Sellers, 1983, British journal of anaesthesia.

Adenosine deaminase isoenzymes of the opossum Didelphis virginiana: initial chromatographic and kinetic studies.

J. E. Lima, D. Abernethy, M. Lieberman, 1995, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Effects of Inhalational Anesthetics on Verapamil Pharmacokinetics in Dogs

J. Chelly, D. Abernethy, M. Doursout, 1986, Anesthesiology.

Potentially toxic serum lidocaine concentrations following spray anesthesia for bronchoscopy

D. Greenblatt, H. Ochs, D. Abernethy, 1983, Klinische Wochenschrift.

Plasma protein binding of drugs after severe burn injury

D. Greenblatt, D. Abernethy, J. Martyn, 1984, Clinical pharmacology and therapeutics.

Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs: VII. Verapamil and thiopental.

P. Wouters, C. Hartley, J. Chelly, 1986, Anesthesiology.

Cardiovascular Effects of and Interaction Between Calcium Blocking Drugs and Anesthetics in Chronically Instrumented Dogs. V. Role of Pharmacokinetics and the Autonomic Nervous System in the Interactions Between Verapamil and Inhalational Anesthetics

J. Chelly, D. Abernethy, Einar S. Hysing, 1987, Anesthesiology.

In vitro correlates of benzodiazepine cerebrospinal fluid uptake, pharmacodynamic action and peripheral distribution.

D. Greenblatt, B. Ehrenberg, R. Shader, 1983, The Journal of pharmacology and experimental therapeutics.

Role of isoflurane on hemodynamic properties and disposition of nicardipine.

C. Hartley, J. Chelly, D. Abernethy, 1987, The Journal of pharmacology and experimental therapeutics.

Age Effects on Alpha‐1‐Acid Glycoprotein Concentration and Imipramine Plasma Protein Binding

D. Abernethy, L. Kerzner, 1984, Journal of the American Geriatrics Society.

Interaction of propoxyphene with diazepam, alprazolam and lorazepam.

D. Greenblatt, R. Shader, D. Abernethy, 1985, British journal of clinical pharmacology.

Diltiazem treatment impairs hepatic drug oxidation: Studies of antipyrine

D. Abernethy, G. Carrum, J. M. Egan, 1986, Clinical pharmacology and therapeutics.

Method for the determination of 5,5-diphenylbarbituric acid and its separation from 1,3-dimethoxymethyl-5,5-diphenylbarbituric acid in plasma by high-performance liquid chromatography.

D. Abernethy, D. Flockhart, D. Thacker, 1998, Journal of chromatography. B, Biomedical sciences and applications.

Ibuprofen disposition in obese individuals.

D R Abernethy, D J Greenblatt, D. Greenblatt, 1985, Arthritis and rheumatism.

Impairment of lidocaine clearance in elderly male subjects.

D. Greenblatt, D. Abernethy, 1983, Journal of cardiovascular pharmacology.

Benzodiazepine kinetics: implications for therapeutics and pharmacogeriatrics.

D. Greenblatt, R. Shader, H. Ochs, 1983, Drug metabolism reviews.

Influence of Oral Contraceptive Use and Cigarette Smoking, Alone and Together, on Antipyrine Pharmacokinetics

D. Greenblatt, J. Harmatz, R. Shader, 1997, Journal of clinical pharmacology.

Cardiovascular Effects of and Interaction Between Calcium Blocking Drugs and Anesthetics in Chronically Instrumented Dogs. VI. Verapamil and Fentanyl‐pancuronium

J. Chelly, D. Abernethy, M. Doursout, 1988, Anesthesiology.

Functional coupling of human L-type Ca2+ channels and angiotensin AT1A receptors coexpressed in xenopus laevis oocytes: involvement of the carboxyl-terminal Ca2+ sensors.

M. Morad, D. Abernethy, M. Oz, 1998, Molecular pharmacology.

Ticlopidine inhibition of phenytoin metabolism mediated by potent inhibition of CYP2C19

D. Abernethy, D. Flockhart, J. Ko, 1997, Clinical pharmacology and therapeutics.

Plasma adenosine deaminase2, is a marker for human immunodeficiency virus‐1 seroconversion

D. Abernethy, K. Mayer, J. G. Niedzwicki, 1991, American journal of hematology.

Grapefruits and drugs: when is statistically significant clinically significant?

D. Abernethy, 1997, The Journal of clinical investigation.

Pharmacokinetics of Calcium Antagonists Under Development

D. Abernethy, J. Schwartz, Darrell R. Abernethy, 1988, Clinical pharmacokinetics.

Molecular basis of cardiovascular drug metabolism: implications for predicting clinically important drug interactions.

D. Abernethy, D. Flockhart, 2000, Circulation.

Structure-functional diversity of human L-type Ca2+ channel: perspectives for new pharmacological targets.

D. Abernethy, N. Soldatov, 2002, The Journal of pharmacology and experimental therapeutics.

Calcium-antagonist drugs.

D. Abernethy, J. Schwartz, 1999, The New England journal of medicine.

Effect of drugs which alter microsomal drug-metabolizing enzyme activity on rat hepatic cholesterol biosynthesis.

D. Abernethy, D. Azarnoff, 1977, Biochemical pharmacology.

Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone

D. Abernethy, D. Flockhart, J. Collins, 1998, Clinical pharmacology and therapeutics.

Pharmacokinetics and dynamics of (+/-)-verapamil in lean and obese Zucker rats.

D. Abernethy, E. Todd, 1986, The Journal of pharmacology and experimental therapeutics.

Triazolam and ethanol interaction: Kinetic and dynamic consequences

D. Greenblatt, E. Sellers, D. Abernethy, 1985, Clinical pharmacology and therapeutics.

Drug therapy. Current status of benzodiazepines.

D. Greenblatt, R. Shader, D. Abernethy, 1983, The New England journal of medicine.

Use of Wavelet and Fast Fourier Transforms in Pharmacodynamics

Donald E Mager, Darrell R Abernethy, D. Mager, 2007, Journal of Pharmacology and Experimental Therapeutics.

Medication therapy in older adults

D. Abernethy, D. Gnjidic, S. Lau, 2022, Atkinson's Principles of Clinical Pharmacology.

Chapter 26 – Drug Therapy in the Elderly

D. Abernethy, S. Lau, 2012 .

Drug Therapy in the Elderly

D. Abernethy, 2007 .

Alprazolam kinetics in the elderly. Relation to antipyrine disposition.

D. Greenblatt, R. Shader, D. Abernethy, 1983, Archives of general psychiatry.

Geriatric drug evaluation: where are we now and where should we be in the future?

D. Abernethy, E. Pfuma, S. Lau, 2011, Archives of internal medicine.

Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid

H. Jamieson, R. Cabo, D. Abernethy, 2007, Experimental Gerontology.

Systematic and quantitative assessment of the effect of chronic kidney disease on CYP2D6 and CYP3A4/5

I. Zineh, L. Zhang, S‐M Huang, 2016, Clinical pharmacology and therapeutics.

Prolonged Accumulation of Diazepam in Obesity

D. Greenblatt, R. Shader, D. Abernethy, 1983, Journal of clinical pharmacology.

Paracetamol absorption from a feeding jejunostomy.

D. Greenblatt, D. Abernethy, E. Nelson, 1986, British journal of clinical pharmacology.

Plasma levels of trazodone: methodology and applications.

D. Greenblatt, R. Shader, D. Abernethy, 1984, Pharmacology.

Prolongation of drug half-life due to obesity: studies of desmethyldiazepam (clorazepate).

D. Greenblatt, R. Shader, D. Abernethy, 1982, Journal of pharmaceutical sciences.

Impairment of diazepam clearance with low-dose oral contraceptive steroid therapy

D. Greenblatt, D. Abernethy, M. Divoll, 1982 .

Obesity effects on nitrazepam disposition.

D. Greenblatt, J. Harmatz, R. Shader, 1986, British journal of clinical pharmacology.

In Vitro-In Vivo Extrapolation of Metabolism- and Transporter-Mediated Drug-Drug Interactions-Overview of Basic Prediction Methods.

Shiew-Mei Huang, Lei Zhang, A. Galetin, 2017, Journal of pharmaceutical sciences.

Noninteraction of temazepam and cimetidine.

D. Greenblatt, J. Harmatz, R. Shader, 1984, Journal of pharmaceutical sciences.

Age, sex, and nitrazepam kinetics: Relation to antipyrine disposition

D R Abernethy, J S Harmatz, D J Greenblatt, 1985, Clinical pharmacology and therapeutics.

Tyrosine kinase-targeting drugs-associated heart failure

G Rennert, D R Abernethy, N. Gronich, 2017, British Journal of Cancer.

Methods for the determination of lorazepam and chlordiazepoxide and metabolites in brain tissue. A comparison with plasma concentrations in the rat.

S. File, D. Greenblatt, R. Lister, 1983, Journal of chromatography.

Simultaneous Modeling of Abciximab Plasma Concentrations and ex Vivo Pharmacodynamics in Patients Undergoing Coronary Angioplasty

D. Mager, M. Mascelli, D. Fitzgerald, 2003, Journal of Pharmacology and Experimental Therapeutics.

A Pilot Randomized Clinical Trial Utilizing the Drug Burden Index to Reduce Exposure to Anticholinergic and Sedative Medications in Older People

D. L. Couteur, D. Abernethy, S. Hilmer, 2010, The Annals of pharmacotherapy.

The pharmacokinetics of diazepam and desmethyldiazepam in rat brain and plasma

D. Greenblatt, R. Shader, D. Abernethy, 1986, Psychopharmacology.

Benzodiazepine hypnotics: kinetic and therapeutic options.

D. Greenblatt, R. Shader, D. Abernethy, 1982, Sleep.

A practitioner's point of view

D. Abernethy, 1991 .

Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam

D. Greenblatt, J. Harmatz, R. Shader, 1983, Psychopharmacology.

Molecular, Biologic, and Pharmacokinetic Properties of Monoclonal Antibodies: Impact of These Parameters on Early Clinical Development

M. Mascelli, D. Abernethy, R. Sweet, 2007, Journal of clinical pharmacology.

High‐Risk Prescribing and Incidence of Frailty Among Older Community‐Dwelling Men

F. Blyth, R. Cumming, V. Naganathan, 2012, Clinical pharmacology and therapeutics.

Stereochemistry of an Agonist Determines Coupling Preference of β2-Adrenoceptor to Different G Proteins in Cardiomyocytes

Darrell R. Abernethy, Irving W. Wainer, D. Abernethy, 2009, Molecular Pharmacology.

Molecular Determinants of L-type Ca2+ Channel Inactivation

M. Morad, D. Abernethy, M. Oz, 1998, The Journal of Biological Chemistry.

Pharmacoepidemiology in the postmarketing assessment of the safety and efficacy of drugs in older adults.

D. Abernethy, S. Hilmer, D. Gnjidic, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Diltiazem and desacetyldiltiazem analysis in human plasma using high-performance liquid chromatography: improved sensitivity without derivation.

D. Abernethy, J. Schwartz, E. Todd, 1985, Journal of chromatography.

Metabolite inhibition of parent drug biotransformation. Studies of diltiazem.

D. Abernethy, T. H. Dickinson, S. Tsao, 1990, Drug metabolism and disposition: the biological fate of chemicals.

Lorazepam analysis using liquid chromatography: improved sensitivity for single-dose pharmacokinetic studies.

D. Abernethy, J. M. Egan, 1986, Journal of chromatography.

, Lorazepam , andFlurazepam

D. Greenblatt, R. Shader, D. Abernethy, 2004 .

Ranitidine does not impair oxidative or conjugative metabolism: Noninteraction with antipyrine, diazepam, and lorazepam

D. Greenblatt, R. Shader, D. Abernethy, 1984, Clinical pharmacology and therapeutics.

Physical and Cognitive Performance and Burden of Anticholinergics, Sedatives, and ACE Inhibitors in Older Women

D. Abernethy, S. Yasar, V. Crentsil, 2008, Clinical pharmacology and therapeutics.

Haloperidol determination in serum and cerebrospinal fluid using gas--liquid chromatography with nitrogen--phosphorus detection: application to pharmacokinetic studies.

D. Greenblatt, R. Shader, H. Ochs, 1984, Journal of Chromatography A.

Pharmacokinetics, central nervous system uptake, and lipid solubility of propranolol, acebutolol, and sotalol.

D R Abernethy, D J Greenblatt, D. Greenblatt, 1984, Cardiology.

Effects of the physical work environment on physiological measures of stress

Darrell R. Abernethy, Julian F. Thayer, John J. Sollers, 2010, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

An improved method of encapsulation of doxorubicin in liposomes: pharmacological, toxicological and therapeutic evaluation.

A. Dritschilo, D. Abernethy, Aquilur Rahman, 1996, British Journal of Cancer.

Oral 5-fluorouracil in psoriasis: pharmacokinetic-pharmacodynamic relationships.

P. Calabresi, D. Abernethy, M. Wiemann, 1989, Pharmacology.

Drug Burden Index and Beers Criteria: Impact on Functional Outcomes in Older People Living in Self‐Care Retirement Villages

D. Abernethy, S. Hilmer, D. Gnjidic, 2012, Journal of clinical pharmacology.

An investigation of the cause of accumulation of verapamil during regular dosing in patients.

D. Abernethy, J. Schwartz, J. Mitchell, 1985, British journal of clinical pharmacology.

Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop

J. Hanlon, M. Rich, K. Schmader, 2018, Journal of the American Geriatrics Society.

Pharmacodynamic and pharmacokinetic interactions between lidocaine and verapamil.

J. Chelly, D. Abernethy, M. Doursout, 1987, The Journal of pharmacology and experimental therapeutics.

Forearm vascular alpha 1-adrenergic blockade by verapamil.

D. Abernethy, L. Winterbottom, 1990, Clinical pharmacology and therapeutics.

Notice of Concern

D. Abernethy, 2006, Pharmacological Reviews.

Serum haloperidol concentrations and clinical response in acute psychosis.

D. Greenblatt, L. Hershey, D. Abernethy, 1984, Journal of clinical psychopharmacology.

Drug Burden Index and physical function in older Australian men.

R. Cumming, V. Naganathan, D. Abernethy, 2009, British journal of clinical pharmacology.

Regulating manufacturer‐affiliated communication in the information age

K. Schulman, S. Rathore, D. Abernethy, 1999, Clinical pharmacology and therapeutics.

Improved liquid chromatographic analysis of phenytoin and salicylate using radial compression separation.

D. Greenblatt, D. Abernethy, R. Matlis, 1983, Journal of chromatography.

Drug Burden Index and Its Association With Hip Fracture Among Older Adults: A National Population-Based Study.

V. Mor, H. Jamieson, D. Abernethy, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Determination of Ro 15-1788, a benzodiazepine antagonist, in human plasma by gas-liquid chromatography with nitrogen-phosphorus detection. Application to single-dose pharmacokinetic studies.

D. Greenblatt, D. Abernethy, P. Lauven, 1983, Pharmacology.

Antipyrine Kinetics in Patients with Primary Biliary Cirrhosis

M. Kaplan, D. Greenblatt, D. Abernethy, 1993, Journal of clinical pharmacology.

Labetalol Analysis in Human Plasma Using Liquid Chromatography with Electrochemical Detection: Application to Pharmacokinetic Studies

D. Abernethy, G. Carrum, E. Todd, 1986 .

Serum protein signatures detect early radiographic osteoarthritis.

L. Ferrucci, S. Ling, D. Taub, 2009, Osteoarthritis and cartilage.

Lack of interaction between verapamil and cimetidine

D. Abernethy, J. Schwartz, E. Todd, 1985, Clinical pharmacology and therapeutics.

Drug Burden and its Association with Falls Among Older Adults in New Zealand: A National Population Cross-Sectional Study

H. Jamieson, D. Abernethy, P. Schluter, 2017, Drugs & Aging.

Pharmacokinetic aspects of drug therapy in the elderly.

D. Greenblatt, R. Shader, D. Abernethy, 1986, Therapeutic drug monitoring.

HANDLS Co-Investigators

N. Shock, D. Abernethy, N. Ejiogu, 2004 .

Antipyretic analgesic drugs as models for studies of drug disposition in old age.

D. Greenblatt, R. Shader, H. Ochs, 1983, The American journal of medicine.

Kinetics of low-dose intravenous antipyrine: use of liquid chromatography.

D. Greenblatt, D. Abernethy, M. Divoll, 1983, International journal of clinical pharmacology, therapy, and toxicology.

Antipyrine determination in human plasma by gas--liquid chromatography using nitrogen--phosphorus detection.

D. Greenblatt, D. Abernethy, A. Zumbo, 1981, Journal of chromatography.

Ibuprofen Does Not Impair Antipyrine Clearance

D. Greenblatt, D. Abernethy, 1983, Journal of clinical pharmacology.

Electromyographic patterns suggest changes in motor unit physiology associated with early osteoarthritis of the knee.

D R Abernethy, S. Ling, R. Conwit, 2007, Osteoarthritis and cartilage.

Impairment of hepatic drug oxidation by propoxyphene.

D. Greenblatt, R. Shader, D. Abernethy, 1982, Annals of internal medicine.

Notes of the American Society for Clinical Pharmacology and Therapeutics

Darrell R. Abernethy, D. Abernethy, 1991 .

Antipyrine kinetics in the elderly: Prediction of benzodiazepine oxidizing capacity

D. Greenblatt, D. Abernethy, M. Divoll, 1981 .

Functional food ingredient quality: Opportunities to improve public health by compendial standardization

D. Abernethy, R. Williams, J. C. Griffiths, 2009 .

GPS for QSP: A Summary of the ACoP6 Symposium on Quantitative Systems Pharmacology and a Stage for Near‐Term Efforts in the Field

DA Lauffenburger, CJ Musante, DR Abernethy, 2016, CPT: pharmacometrics & systems pharmacology.

Stereoselective verapamil disposition and dynamics in aging during racemic verapamil administration.

D. Abernethy, J. Longstreth, I. Wainer, 1993, The Journal of pharmacology and experimental therapeutics.

Treatment of diazepam withdrawal syndrome with propranolol.

D. Greenblatt, R. Shader, D. Abernethy, 1981, Annals of Internal Medicine.

Verapamil blocks basal and angiotensin II-induced RNA synthesis of rat aortic vascular smooth muscle cells.

D. Abernethy, N. Andrawis, 1992, Biochemical and biophysical research communications.

Verapamil pharmacodynamics and disposition in obese hypertensive patients.

D. Abernethy, J. Schwartz, 1988, Journal of cardiovascular pharmacology.

Amlodipine: pharmacokinetic profile of a low-clearance calcium antagonist.

D. Abernethy, 1991, Journal of cardiovascular pharmacology.

Voltage-gated Mobility of the Ca2+ Channel Cytoplasmic Tails and Its Regulatory Role*

D. Abernethy, E. Kobrinsky, N. Soldatov, 2003, The Journal of Biological Chemistry.

Use of Internet Search Logs to Evaluate Potential Drug Adverse Events

S Sarntivijai, D R Abernethy, D. Abernethy, 2014, Clinical pharmacology and therapeutics.

The effect of propylene glycol on antipyrine clearance in humans

D. Abernethy, E. Nelson, J. M. Egan, 1987, Clinical pharmacology and therapeutics.

Identification of plasma membrane macro- and microdomains from wavelet analysis of FRET microscopy.

D. Mager, D. Abernethy, S. Murata, 2005, Biophysical journal.

Change in Criteria for USP Dissolution Performance Verification Tests

W. Hauck, D. Abernethy, A. Destefano, 2009, AAPS PharmSciTech.

Reduced distribution and clearance of acetaminophen in patients with congestive heart failure.

D. Greenblatt, H. Ochs, D. Abernethy, 1983, Journal of cardiovascular pharmacology.

Adverse Event Detection and Labeling in Pediatric Drug Development: Antiretroviral Drugs

D. Abernethy, E. Capparelli, J. Momper, 2015, Therapeutic innovation & regulatory science.

Imipramine and desipramine disposition in the elderly.

D. Greenblatt, R. Shader, D. Abernethy, 1985, The Journal of pharmacology and experimental therapeutics.

Cimetidine impairs nitrazepam clearance

D. Greenblatt, H. Ochs, R. Gugler, 1983, Clinical pharmacology and therapeutics.

Differential role of the alpha1C subunit tails in regulation of the Cav1.2 channel by membrane potential, beta subunits, and Ca2+ ions.

E. Lakatta, D. Abernethy, V. Maltsev, 2005, The Journal of biological chemistry.

Making sense of trueness, precision, accuracy, and uncertainty

Darrell R. Abernethy, William F. Koch, Roger L. Williams, 2008 .

Trimipramine kinetics and absolute bioavailability: Use of gas‐liquid chromatography with nitrogen‐phosphorus detection

D. Greenblatt, R. Shader, D. Abernethy, 1984, Clinical pharmacology and therapeutics.

Voltage-gated rearrangements associated with differential beta-subunit modulation of the L-type Ca(2+) channel inactivation.

H. Kahr, C. Romanin, D. Abernethy, 2004, Biophysical journal.

Replication – why we need to publish our findings

D. Abernethy, M. Curtis, 2015, Pharmacology research & perspectives.

Advice on statistical analysis, and new journal guidance for experimental design and analysis

Michael J Curtis, Darrell R Abernethy, D. Abernethy, 2014, Pharmacology research & perspectives.

Steady state verapamil tissue distribution in the dog: differing tissue accumulation.

D. Abernethy, J. Schwartz, J. Mitchell, 1986, Pharmacology.

Pharmacokinetics of benzodiazepine hypnotics.

D. Greenblatt, R. Shader, D. Abernethy, 1982, International pharmacopsychiatry.

IUPHAR International geriatric clinical pharmacology curriculum for medical students.

D. Abernethy, D. L. Le Couteur, S. Hilmer, 2019, Pharmacological research.

Drug Burden Index and Beers Criteria: Impact on Functional Outcomes in Older People Living in Self‐Care Retirement Villages

D. Abernethy, S. Hilmer, D. Gnjidic, 2012, Journal of clinical pharmacology.

Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel α1C subunit

D. Abernethy, Jennifer J. Heller, N. Soldatov, 2006, Proceedings of the National Academy of Sciences.

Aging and Medications: Past, Present, Future

D. Abernethy, J. Schwartz, 2009 .

Reducing drugs in older adults is more.

D. Abernethy, D. L. Le Couteur, S. Hilmer, 2011, Archives of internal medicine.

High‐Risk Prescribing and Incidence of Frailty Among Older Community‐Dwelling Men

F. Blyth, R. Cumming, V. Naganathan, 2012, Clinical pharmacology and therapeutics.

Ranitidine does not impair oxidative or conjugative metabolism: Noninteraction with antipyrine, diazepam, and lorazepam

D. Greenblatt, R. Shader, D. Abernethy, 1984, Clinical pharmacology and therapeutics.

NMR investigation of histamine-phospholipid interaction.

D. Abernethy, T. J. Fitzgerald, E. Walaszek, 1974, Biochemical and biophysical research communications.

Use of saliva lithium determinations for monitoring lithium therapy.

S. Preskorn, D. Abernethy, W. McKnelly, 1978, The Journal of clinical psychiatry.

Serum protein signatures detect early radiographic osteoarthritis.

E. Metter, M. Vaduganathan, D. Abernethy, 2009, Osteoarthritis and cartilage.

Ticlopidine inhibits phenytoin clearance

D. Abernethy, D. Flockhart, S. Donahue, 1999, Clinical pharmacology and therapeutics.