Jason D. Roberts

发表

Exercise and Arrhythmic Risk in TMEM43 p.S358L Arrhythmogenic Right Ventricular Cardiomyopathy.

P. Parfrey, F. Paulin, K. Hodgkinson, 2020, Heart rhythm.

A large familial pathogenic Plakophilin-2 gene (PKP2) deletion manifesting with sudden cardiac death and lone atrial fibrillation: Evidence for alternating atrial and ventricular phenotypes

Jason D. Roberts, K. Cunningham, Saad Alhassani, 2018, HeartRhythm case reports.

Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial

Edward O'Brien, Marino Labinaz, George A Wells, 2012, The Lancet.

Overcoming obstacles in pharmacogenomic strategies for antiplatelet drugs: are we RAPID enough?

Jason D. Roberts, D. So, Jason D. Roberts, 2012, Pharmacogenomics.

Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals.

E. Ziv, E. Burchard, M. Perez, 2016, JAMA cardiology.

Association Between QT-Interval Components and Sudden Cardiac Death: The ARIC Study (Atherosclerosis Risk in Communities)

Larisa G. Tereshchenko, Matthew J. Singleton, Gregory M. Marcus, 2017, Circulation. Arrhythmia and electrophysiology.

Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site.

E. Kaufman, C. January, E. Behr, 2019, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Hemodynamically tolerated ventricular tachycardia with mildly impaired ejection fraction - Do these patients have VT/VF recurrence and ICD therapies?

A. Skanes, G. Klein, R. Yee, 2022, The Canadian journal of cardiology.

Guidance on Minimizing Risk of Drug-Induced Ventricular Arrhythmia During Treatment of COVID-19: A Statement from the Canadian Heart Rhythm Society

J. Healey, A. Krahn, Jason D. Roberts, 2020, Canadian Journal of Cardiology.

Arrhythmogenic Right Ventricular Cardiomyopathy.

H. Calkins, A. Wilde, A. Krahn, 2022, JACC. Clinical electrophysiology.

Arrhythmogenic Cardiomyopathy: Molecular Insights for Improved Therapeutic Design

Jason D. Roberts, P. Mohler, S. Koenig, 2020, Journal of cardiovascular development and disease.

Impact of a 4q25 Genetic Variant in Atrial Flutter and on the Risk of Atrial Fibrillation After Cavotricuspid Isthmus Ablation

J. Olgin, G. Marcus, M. Malloy, 2014, Journal of cardiovascular electrophysiology.

Successful management of left ventricular free wall rupture.

Jason D. Roberts, B. Sussex, K. Mong, 2007, The Canadian journal of cardiology.

TJP1 Mutations in Arrhythmogenic Cardiomyopathy.

Jason D. Roberts, Jason D. Roberts, 2018, Circulation. Genomic and precision medicine.

A Molecular Genetic Perspective on Atrial Fibrillation

M. Gollob, Jason D. Roberts, J. Roberts, 2020, Clinical Cardiogenetics.

Predicting Penetrance of SCN5A Rare Variants: Peering Beyond the Black and White and Into the Shades of Grey.

Jason D. Roberts, Jason D. Roberts, 2018, Circulation. Genomic and precision medicine.

The Optimal Timing of Primary Prevention Implantable Cardioverter-Defibrillator Referral in the Rapidly Changing Medical Landscape.

J. Healey, Jason D. Roberts, J. Wong, 2021, The Canadian journal of cardiology.

Pharmacogenetic guidance for antiplatelet treatment – Authors' reply

Jason D. Roberts, D. So, Jason D. Roberts, 2012, The Lancet.

Acute coronary thrombosis in a patient with diabetes and severe hyperglycemia.

D. Fitchett, Jason D. Roberts, G. Oudit, 2009, The Canadian journal of cardiology.

Inherited cardiomyopathies mimicking arrhythmogenic right ventricular cardiomyopathy.

M. Gollob, Jason D. Roberts, J. Rutberg, 2010, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

The Canadian Arrhythmogenic Right Ventricular Cardiomyopathy Registry: Rationale, Design, and Preliminary Recruitment.

J. Healey, A. Krahn, M. Gardner, 2016, The Canadian journal of cardiology.

Comparison of radionuclide angiographic synchrony analysis to echocardiography and magnetic resonance imaging for the diagnosis of arrhythmogenic right ventricular cardiomyopathy.

Kurt S. Hoffmayer, E. Botvinick, M. Scheinman, 2015, Heart rhythm.

Arrhythmic risk prediction in arrhythmogenic right ventricular cardiomyopathy: external validation of the arrhythmogenic right ventricular cardiomyopathy risk calculator

J. Healey, H. Calkins, S. Priori, 2022, European heart journal.

Role of Common Genetic Variation in Lone Atrial Fibrillation.

A. Skanes, R. Hegele, L. Gula, 2021, Circulation. Genomic and precision medicine.

Not a broken heart

Jason D. Roberts, A. Sawka, S. Mak, 2007, The Lancet.

Concomitant Isolation of the Pulmonary Veins and Posterior Wall Using a Box Lesion Set in a Patient with Persistent Atrial Fibrillation and Variant Pulmonary Venous Anatomy.

E. Gerstenfeld, Jason D. Roberts, 2016, Cardiac electrophysiology clinics.

Identification and in-silico characterization of splice-site variants from a large cardiogenetic national registry

J. Healey, A. Krahn, S. Kimber, 2022, European Journal of Human Genetics.

Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.

J. Healey, E. Behr, A. Krahn, 2019, JACC. Clinical electrophysiology.

Early Repolarization Pattern Inheritance in the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER).

J. Healey, A. Krahn, M. Gardner, 2018, JACC. Clinical electrophysiology.

Importance of genetic testing in unexplained cardiac arrest

J. Healey, G. Lettre, A. Krahn, 2022, European heart journal.

One family’s clinical odyssey from evolving phenotypic and genotypic knowledge of catecholaminergic polymorphic ventricular tachycardia and long QT syndrome

Jason D. Roberts, S. Franciosi, C. Johnsrude, 2022, HeartRhythm case reports.

A simple maneuver to determine if septal accessory pathway ablation requires a left atrial approach

A. Skanes, G. Klein, R. Yee, 2020, Journal of cardiovascular electrophysiology.

Early Repolarization: A Rare Primary Arrhythmic Syndrome and Common Modifier of Arrhythmic Risk

M. Gollob, Jason D. Roberts, J. Roberts, 2013, Journal of cardiovascular electrophysiology.

Early Repolarization in Long QT Syndrome: Modifier of Arrhythmic Risk or Benign Incidental Finding?

L. Gula, Jason D. Roberts, J. Roberts, 2018, JACC. Clinical electrophysiology.

Early Repolarization in Long€QT€Syndrome

L. Gula, Jason D. Roberts, J. Roberts, 2022 .

Case Report Inherited cardiomyopathies mimicking arrhythmogenic right ventricular cardiomyopathy

M. Gollob, Jason D. Roberts, J. Rutberg, 2010 .

Endocrinopathies mimicking gene negative long QT syndrome.

M. Gollob, Jason D. Roberts, P. Chakraborty, 2021, Cardiology in the young.

The Incremental Value of the Signal Averaged ECG for Diagnosing Arrhythmogenic Cardiomyopathy.

A. Krahn, Jason D. Roberts, M. Talajic, 2022, Heart rhythm.

Sex Differences and Utility of Treadmill Testing in Long‐QT Syndrome

J. Healey, A. Krahn, S. Kimber, 2022, Journal of the American Heart Association.

An International Multicenter Cohort Study on β-Blockers for the Treatment of Symptomatic Children With Catecholaminergic Polymorphic Ventricular Tachycardia

J. Skinner, E. Behr, P. Schwartz, 2021, Circulation.

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

P. Elliott, P. Matthews, D. O’Regan, 2020, Nature Genetics.

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

K. Lunetta, A. Hofman, A. Uitterlinden, 2012, Nature Genetics.

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

R. Redon, K. Strauch, P. Lambiase, 2022, Nature Genetics.

Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy

Kevin Knight, D. O’Regan, Y. Pinto, 2023, medRxiv.

Variant Reinterpretation in Survivors of Cardiac Arrest With Preserved Ejection Fraction (the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry) by Clinicians and Clinical Commercial Laboratories

J. Healey, A. Krahn, M. Gardner, 2021, Circulation. Genomic and precision medicine.

Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.

John F. Robinson, L. Mestroni, J. Healey, 2019, The Journal of clinical investigation.

Enrichment of loss-of-function and copy number variants in ventricular cardiomyopathy genes in 'lone' atrial fibrillation.

John F. Robinson, S. Scherer, A. Skanes, 2021, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Return of Results Policies for Genomic Research: Current Practices & The Hearts in Rhythm Organization Approach.

J. Healey, A. Krahn, S. Kimber, 2021, The Canadian journal of cardiology.

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

R. Redon, P. Lambiase, P. Ellinor, 2020, Genetics in medicine : official journal of the American College of Medical Genetics.

Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia.

A. Wilde, W. Shimizu, M. Ackerman, 2019, Heart rhythm.

Bundle Branch Reentrant Ventricular Tachycardia : Novel Genetic Mechanisms in a Life-Threatening Arrhythmia

P. Kwok, V. Vedantham, J. Olgin, 2016 .

The burgeoning field of ablatogenomics.

G. Marcus, Jason D. Roberts, 2015, Circulation. Arrhythmia and electrophysiology.

Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation?

J. Healey, E. Behr, A. Moss, 2017, Circulation. Arrhythmia and electrophysiology.

Genetic Testing in the Evaluation of Unexplained Cardiac Arrest: From the CASPER (Cardiac Arrest Survivors With Preserved Ejection Fraction Registry)

J. Healey, A. Krahn, G. Klein, 2017, Circulation. Cardiovascular genetics.

Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome

Jason D. Roberts, L. A. Swayne, L. Arbour, 2017, Circulation. Cardiovascular genetics.

The evolution of gene‐guided management of inherited arrhythmia syndromes: Peering beyond monogenic paradigms towards comprehensive genomic risk scores

Jason D. Roberts, M. Rowe, J. Roberts, 2020, Journal of cardiovascular electrophysiology.

Cardiac Abnormalities in First-Degree Relatives of Unexplained Cardiac Arrest Victims: A Report From the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry

J. Healey, A. Krahn, G. Klein, 2016, Circulation. Arrhythmia and electrophysiology.

Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation.

E. Benjamin, P. Ellinor, R. Davies, 2010, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

C. Collins, S. Volik, Jason D. Roberts, 2023, bioRxiv.

Targeted Deep Sequencing Reveals No Definitive Evidence for Somatic Mosaicism in Atrial Fibrillation

P. Kwok, J. Olgin, G. Marcus, 2014, Circulation. Cardiovascular genetics.

Understanding the Genetic Basis of Atrial Fibrillation: Towards a Pharmacogenetic Approach for Arrhythmia Treatment

M. Gollob, Jason D. Roberts, J. Roberts, 2014 .

Management of Congenital Long-QT Syndrome: Commentary From the Experts

M. Chung, E. Kaufman, S. Priori, 2021, Circulation. Arrhythmia and electrophysiology.

The genetic and clinical features of cardiac channelopathies.

M. Gollob, Jason D. Roberts, J. Roberts, 2010, Future cardiology.

Who is at risk of atrial fibrillation?

Thalia Shoshana Field, J. Healey, Jason D. Roberts, 2021, Heart rhythm.

Ablatogenomics: can genotype guide catheter ablation for cardiac arrhythmias?

G. Marcus, Jason D. Roberts, J. Roberts, 2016, Pharmacogenomics.

Electrocardiographic intervals associated with incident atrial fibrillation: Dissecting the QT interval.

L. Chen, E. Vittinghoff, G. Marcus, 2017, Heart rhythm.

Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation.

L. Chen, J. Olgin, G. Marcus, 2016, American heart journal.

Impact of genetic discoveries on the classification of lone atrial fibrillation.

M. Gollob, Jason D. Roberts, J. Roberts, 2010, Journal of the American College of Cardiology.

Pseudo Pseudo A‐A‐V Response: What is the Mechanism?

G. Marcus, Jason D. Roberts, 2015, Pacing and clinical electrophysiology : PACE.

Telomere Length and the Risk of Atrial Fibrillation: Insights Into the Role of Biological Versus Chronological Aging

E. Ziv, E. Burchard, J. Olgin, 2014, Circulation. Arrhythmia and electrophysiology.

Telomere Length and the Risk of Atrial Fibrillation: Insights Into the Role of Biological Versus Chronological Aging

E. Ziv, E. Burchard, J. Olgin, 2014, Circulation: Arrhythmia and Electrophysiology.

Atrial flutter and atrial fibrillation ablation - sequential or combined? A cost-benefit and risk analysis of primary prevention pulmonary vein ablation.

A. Skanes, G. Klein, R. Yee, 2016, Heart rhythm.

Alcohol consumption and leukocyte telomere length

E. Vittinghoff, G. Marcus, Jue Lin, 2019, Scientific Reports.

Management of Inherited Arrhythmia Syndromes: A HiRO Consensus Handbook on Process of Care

J. Healey, A. Krahn, S. Kimber, 2023, CJC open.

Clinical and Functional Characterization of Ryanodine Receptor 2 Variants Implicated in Calcium-Release Deficiency Syndrome.

Jeffrey M. Vinocur, A. Wilde, A. Krahn, 2021, JAMA cardiology.

Short-coupled ventricular fibrillation represents a distinct phenotype among latent causes of unexplained cardiac arrest: a report from the CASPER registry.

J. Healey, A. Krahn, M. Gardner, 2021, European heart journal.

Defining Idiopathic Ventricular Fibrillation: A Systematic Review of Diagnostic Testing Yield in Apparently Unexplained Cardiac Arrest.

A. Krahn, Jason D. Roberts, Martin S. Green, 2021, Heart rhythm.

An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia

Rahul C. Deo, J. Healey, C. January, 2020, Circulation.

The Hearts in Rhythm Organization: A Canadian National Cardiogenetics Network

J. Healey, A. Krahn, S. Kimber, 2020, CJC open.

Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

J. Skinner, P. Schwartz, A. Wilde, 2020, Circulation. Arrhythmia and electrophysiology.

An International Multicenter Evaluation of Type 5 Long QT Syndrome

M. Perez, E. Kaufman, E. Vittinghoff, 2020, Circulation.

Initially Unexplained Cardiac Arrest in Children and Adolescents: A National Experience from the Canadian Pediatric Heart Rhythm Network.

F. Dallaire, S. Udupa, Jason D. Roberts, 2020, Heart rhythm.

An International Multicenter Evaluation of Type 5 Long QT Syndrome

M. Perez, E. Kaufman, E. Vittinghoff, 2020, Circulation.

Short QT Syndrome

Jason D. Roberts, B. Deif, J. Roberts, 2020, Electrocardiography of Inherited Arrhythmias and Cardiomyopathies.

Diagnostic evaluation and arrhythmia mechanisms in survivors of unexplained cardiac arrest

Jason D. Roberts, B. Deif, J. Roberts, 2019, Pacing and clinical electrophysiology : PACE.

Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest.

J. Skinner, E. Behr, P. Schwartz, 2019, European heart journal.

Pregnancy in Catecholaminergic Polymorphic Ventricular Tachycardia.

A. Wilde, A. Krahn, Jason D. Roberts, 2019, JACC. Clinical electrophysiology.

Challenge and Impact of Quinidine Access in Sudden Death Syndromes: A National Experience.

J. Healey, A. Krahn, L. Gula, 2019, JACC. Clinical electrophysiology.

Brugada Syndrome: Evolving Insights and Emerging Treatment Strategies

Jason D. Roberts, S. Duffett, J. Roberts, 2017, The Journal of innovations in cardiac rhythm management.

Rare Disease and Low Event Rates: Challenges for Refining Risk Stratification in Brugada Syndrome.

G. Klein, Jason D. Roberts, J. Roberts, 2016, The Canadian journal of cardiology.

The short QT syndrome: proposed diagnostic criteria.

M. Gollob, Jason D. Roberts, C. Redpath, 2011, Journal of the American College of Cardiology.

Atrial Fibrillation Associated Genetic Variants and Left Atrial Histology: Evaluation for Molecular Sub‐Phenotypes

P. Kwok, J. Olgin, R. Gladstone, 2016, Journal of cardiovascular electrophysiology.

Beyond gene-disease validity: capturing structured data on inheritance, allelic requirement, disease-relevant variant classes, and disease mechanism for inherited cardiac conditions

Angharad M Roberts, V. Novelli, W. Zareba, 2023, Genome Medicine.

Cardiac resynchronization is pro-arrhythmic in the absence of reverse ventricular remodelling: a systematic review and meta-analysis

J. Healey, R. Yee, Jason D. Roberts, 2018, Cardiovascular research.

Cardiac ryanodine receptor calcium release deficiency syndrome

S. Priori, C. Napolitano, A. Wilde, 2021, Science Translational Medicine.

Personalizing therapy for atrial fibrillation: the role of stem cell and in silico disease models

Peter Backx, Patrick M Boyle, Jason D. Roberts, 2018, Cardiovascular research.

Human RyR2 (Ryanodine Receptor 2) Loss-of-Function Mutations

A. Wilde, M. Gollob, Jason D. Roberts, 2021, Circulation. Arrhythmia and electrophysiology.

A contemporary review on the genetic basis of atrial fibrillation.

M. Gollob, Jason D. Roberts, J. Roberts, 2014, Methodist DeBakey cardiovascular journal.

Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant

S. Györke, Jason D. Roberts, N. Malhotra, 2023, The Journal of biological chemistry.

The Utility of Sodium Channel Provocation in Unexplained Cardiac Arrest Survivors and Electrocardiographic Predictors of Ventricular Fibrillation Recurrence

E. Behr, A. Krahn, Jason D. Roberts, 2022, Circulation. Arrhythmia and electrophysiology.

Emerging Targeted Therapies for Inherited Cardiomyopathies and Arrhythmias

Jason D. Roberts, Tammy Ryan, Jason D. Roberts, 2023, Cardiac Electrophysiology Clinics.

Evaluating Polygenic Risk Scores in “Lone” Atrial Fibrillation

A. Skanes, R. Hegele, L. Gula, 2021, CJC open.

Noncoding Genetic Variation and Gene Expression: Deciphering the Molecular Drivers of Genome-Wide Association Study Signals in Atrial Fibrillation.

Jason D. Roberts, Jason D. Roberts, 2018, Circulation. Genomic and precision medicine.

Thyroid Function and the Risk of Atrial Fibrillation: Exploring Potentially Causal Relationships Through Mendelian Randomization.

Jason D. Roberts, Jason D. Roberts, 2019, JAMA cardiology.

Potential Role of Life Stress in Unexplained Sudden Cardiac Arrest

A. Krahn, M. Gardner, Jason D. Roberts, 2020, CJC open.

Elevated Lipoprotein(a) and Risk of Atrial Fibrillation: An Observational and Mendelian Randomization Study.

Y. Bossé, D. Conen, G. Paré, 2022, Journal of the American College of Cardiology.

Epigenetic Age and the Risk of Incident Atrial Fibrillation

S. Horvath, M. Fornage, K. Lunetta, 2021, Circulation.