K. Højlund

K. Højlund, H. Beck-Nielsen, J. Frystyk, 2010, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle

A. Deshmukh, K. Højlund, H. Al-Hasani, 2022, Diabetes.

Differential effects of strength training and testosterone treatment on soluble CD36 in aging men: Possible relation to changes in body composition

D. Hougaard, K. Højlund, A. Handberg, 2015, Scandinavian journal of clinical and laboratory investigation.

Effect of long-term testosterone therapy on molecular regulators of skeletal muscle mass and fibre-type distribution in aging men with subnormal testosterone.

K. Højlund, N. Ørtenblad, M. Andersen, 2020, Metabolism: clinical and experimental.

Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans

K. Højlund, A. Bauer-Brandl, T. Ulven, 2021, Nutrients.

The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes.

K. Højlund, H. Beck-Nielsen, J. Wojtaszewski, 2004, Biochemical and biophysical research communications.

The Human Skeletal Muscle Proteome Project: a reappraisal of the current literature

L. Ferrucci, C. Ubaida-Mohien, K. Højlund, 2016, Journal of cachexia, sarcopenia and muscle.

Skeletal muscle lipid accumulation in type 2 diabetes may involve the liver X receptor pathway.

K. Højlund, H. Beck-Nielsen, G. H. Thoresen, 2005, Diabetes.

Dysregulation of glycogen synthase COOH- and NH2-terminal phosphorylation by insulin in obesity and type 2 diabetes mellitus.

K. Højlund, H. Beck-Nielsen, B. Hansen, 2009, The Journal of clinical endocrinology and metabolism.

Apolipoprotein D and transthyretin are reduced in female adolescent offspring of women with type 1 diabetes: The EPICOM study

K. Højlund, B. Bytoft, S. Knorr, 2021, Diabetic medicine : a journal of the British Diabetic Association.

Epigenetic and transcriptomic alterations in offspring born to women with type 1 diabetes (the EPICOM study)

K. Højlund, B. Bytoft, S. Knorr, 2021, BMC Medicine.

A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene.

T. Hansen, O. Pedersen, K. Højlund, 2004, Diabetes.

Increased Interaction With Insulin Receptor Substrate 1, a Novel Abnormality in Insulin Resistance and Type 2 Diabetes

S. Drăghici, R. Tagett, J. Horowitz, 2014, Diabetes.

Impaired Glucose Tolerance in Healthy Men Treated with St. John's Wort

K. Højlund, K. Brøsen, T. Stage, 2016, Basic & clinical pharmacology & toxicology.

Characterisation of adiponectin multimers and the IGF axis in humans with a heterozygote mutation in the tyrosine kinase domain of the insulin receptor gene.

K. Højlund, H. Beck-Nielsen, J. Frystyk, 2012, European journal of endocrinology.

Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects.

H. Orskov, J. Clausen, K. Højlund, 2005, The Journal of clinical endocrinology and metabolism.

Impaired insulin activation and dephosphorylation of glycogen synthase in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.

K. Højlund, H. Beck-Nielsen, B. Hansen, 2008, The Journal of clinical endocrinology and metabolism.

The effect of empagliflozin on growth differentiation factor 15 in patients with heart failure: a randomized controlled trial (Empire HF Biomarker)

L. Køber, K. Højlund, C. Tuxen, 2022, Cardiovascular Diabetology.

Increased metabolic risk in adolescent offspring of mothers with type 1 diabetes: the EPICOM study

K. Højlund, B. Bytoft, S. Knorr, 2015, Diabetologia.

Fatty Liver Among Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study)

J. Holst, H. Møller, B. Hartmann, 2019, Diabetes Care.

Boström et al. reply

B. Spiegelman, S. Gygi, S. Kajimura, 2012, Nature.

Life-course exposure to perfluoroalkyl substances in relation to markers of glucose homeostasis in early adulthood.

B. Coull, P. Grandjean, D. Valvi, 2021, The Journal of clinical endocrinology and metabolism.

Impaired glycogen synthase activity and mitochondrial dysfunction in skeletal muscle: markers or mediators of insulin resistance in type 2 diabetes?

K. Højlund, H. Beck-Nielsen, 2006, Current diabetes reviews.

Impact of lean body mass and insulin sensitivity on the IGF-I-bone mass axis in adolescence: the EPICOM study.

K. Højlund, B. Bytoft, Tine D Clausen, 2020, The Journal of clinical endocrinology and metabolism.

Obesity-Associated Hypermetabolism and Accelerated Senescence of Bone Marrow Stromal Stem Cells Suggest a Potential Mechanism for Bone Fragility.

Anders K. Haakonsson, T. L. Andersen, M. Frost, 2019, Cell reports.

Metabolism and insulin signaling in common metabolic disorders and inherited insulin resistance.

K. Højlund, 2014, Danish medical journal.

University of Southern Denmark Adrenal activity and metabolic risk during randomized escitalopram or placebo treatment in

K. Højlund, D. Glintborg, M. Andersen, 2018 .

High-intensity interval training combining rowing and cycling efficiently improves insulin sensitivity, body composition and VO2max in men with obesity and type 2 diabetes

K. Højlund, N. Ørtenblad, M. E. de Almeida, 2022, Frontiers in Endocrinology.

Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein*

L. Mandarino, R. Rafikov, K. Højlund, 2017, Molecular & Cellular Proteomics.

The relationship between bone turnover and insulin sensitivity and secretion: Cross-sectional and prospective data from the RISC cohort study.

B. Balkau, M. Frost, K. Højlund, 2018, Bone.

Acute hyperinsulinemia is followed by increased serum concentrations of fibroblast growth factor 23 in type 2 diabetes patients

K. Højlund, K. Winther, M. Nybo, 2012, Scandinavian journal of clinical and laboratory investigation.

Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes

Benjamin P. Bowen, Lawrence J. Mandarino, C. Flynn, 2009, Diabetes.

Risk of severe COVID-19 infection in persons with diabetes during the first and second waves in Denmark: A nationwide cohort study

A. Green, K. Højlund, J. Stidsen, 2022, Frontiers in Endocrinology.

Fasting insulin has a stronger association with an adverse cardiometabolic risk profile than insulin resistance: the RISC study.

O. Melander, G. Nijpels, J. Dekker, 2009, European journal of endocrinology.

Circulating follistatin and activin A and their regulation by insulin in obesity and type 2 diabetes.

K. Højlund, J. Wojtaszewski, E. Richter, 2020, The Journal of clinical endocrinology and metabolism.

Adrenal activity and metabolic risk during randomized escitalopram or placebo treatment in PCOS

K. Højlund, D. Glintborg, M. Andersen, 2018, Endocrine connections.

Free rather than total circulating insulin-like growth factor-I determines the feedback on growth hormone release in normal subjects.

H. Orskov, K. Højlund, H. Beck-Nielsen, 2005, The Journal of clinical endocrinology and metabolism.

Initiation of glucose‐lowering drugs reduces the anticoagulant effect of warfarin—But not through altered drug metabolism in patients with type 2 diabetes

A. Pottegård, L. Donnelly, K. Højlund, 2022, medRxiv.

The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes

J. Borén, C. Ling, E. Larsson, 2010, Diabetes.

Attendance in a national screening program for diabetic retinopathy: a population-based study of 205,970 patients

Kenneth H. Rubin, K. Højlund, C. Laugesen, 2022, Acta Diabetologica.

Initiation of glucose‐lowering treatment decreases international normalized ratio levels among users of vitamin K antagonists: a self‐controlled register study

A. Pottegård, K. Højlund, K. Brøsen, 2016, Journal of thrombosis and haemostasis : JTH.

Physician-led in-hospital multidisciplinary team conferences with multiple medical specialities present - A scoping review

K. Schousboe, K. Højlund, D. Henriksen, 2022, Journal of multimorbidity and comorbidity.

Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

J. Brønd, K. Højlund, H. Beck-Nielsen, 2022, Annals of Internal Medicine.

Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population

Beverley Balkau, Amalia Gastaldelli, B. Balkau, 2009, Hepatology.

Obesity and carotid artery remodeling

P. Nilsson, B. Balkau, C. Morizzo, 2015, Nutrition & Diabetes.

Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes

M. Fraga, P. Poulsen, A. Vaag, 2012, PloS one.

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

L. Mandarino, B. Bowen, W. Willis, 2010, Diabetes.

Increased ROS production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1 B protein despite normal mitochondrial respiration in insulin resistant human skeletal muscle

L. Mandarino, B. Bowen, W. Willis, 2010 .

Loci for insulin processing and secretion provide insight into type 2 diabetes risk

A. Morris, N. Grarup, C. Lindgren, 2023, American journal of human genetics.

Mitochondrial dysfunction in type 2 diabetes and obesity.

K. Sahlin, K. Højlund, H. Beck-Nielsen, 2008, Endocrinology and metabolism clinics of North America.

Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect.

K. Sahlin, K. Højlund, H. Beck-Nielsen, 2005, Biochimica et biophysica acta.

Electronic Supplementary Material -methods

P. Poulsen, A. Vaag, T. Litman, 2022 .

Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the β3‐adrenergic receptor gene

P. Poulsen, K. Højlund, H. Beck-Nielsen, 2006, Diabetes, obesity & metabolism.

Mitochondrial phosphoproteomics of mammalian tissues.

K. Højlund, Rikke Kruse, 2017, Mitochondrion.

Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS.

C. Flynn, L. Mandarino, B. Bowen, 2009, Journal of proteomics.

Characterization of the Human Skeletal Muscle Proteome by One-dimensional Gel Electrophoresis and HPLC-ESI-MS/MS*S

C. Flynn, L. Mandarino, S. Weintraub, 2008, Molecular & Cellular Proteomics.

A PGC1α-dependent myokine that drives browning of white fat and thermogenesis

B. Spiegelman, S. Gygi, S. Kajimura, 2012, Nature.

Follow-up duration influences the relative importance of OGTT and optimal timing of glucose measurements for predicting future type 2 diabetes.

K. Eriksson, P. Nilsson, K. Højlund, 2016, European journal of endocrinology.

Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE).

A. Tura, K. Widhalm, A. Jotic, 2016, Clinical chemistry.

Intact initiation of autophagy and mitochondrial fission by acute exercise in skeletal muscle of patients with Type 2 diabetes.

K. Højlund, J. Wojtaszewski, S. J. Petersson, 2016, Clinical science.

Phosphoproteome Analysis of Functional Mitochondria Isolated from Resting Human Muscle Reveals Extensive Phosphorylation of Inner Membrane Protein Complexes and Enzymes*

Ole Nørregaard Jensen, Martin Mogensen, Ileana R. León, 2010, Molecular & Cellular Proteomics.

Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle

L. Mandarino, B. Bowen, K. Højlund, 2010, Diabetologia.

In vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.

C. Flynn, L. Mandarino, B. Bowen, 2009, Journal of proteome research.

Development and clinical evaluation of a novel immunoassay for the binary complex of IGF-I and IGF-binding protein-1 in human serum.

K. Højlund, J. Frystyk, H. Ørskov, 2002, The Journal of clinical endocrinology and metabolism.

Legends to Supplementary Figures

K. D. Sørensen, B. Spiegelman, T. Ørntoft, 2007 .

Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

R. Helm, Xiaoyong Yang, D. Gerrard, 2018, Molecular metabolism.

Irisin in obesity and type 2 diabetes.

K. Højlund, P. Boström, 2013, Journal of diabetes and its complications.

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

J. Zierath, K. Højlund, H. Beck-Nielsen, 2010, Diabetologia.

Pioglitazone Enhances Mitochondrial Biogenesis and Ribosomal Protein Biosynthesis in Skeletal Muscle in Polycystic Ovary Syndrome

S. Knudsen, K. Højlund, H. Beck-Nielsen, 2008, PloS one.

Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes

E. Oakeley, B. Hemmings, K. Højlund, 2008, Diabetologia.

Novel tyrosine phosphorylation sites in rat skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.

K. Højlund, C. Meyer, Z. Yi, 2012, Journal of proteomics.

Insulin increases phosphorylation of mitochondrial proteins in human skeletal muscle in vivo.

O. Jensen, K. Højlund, Xiaolu Zhao, 2014, Journal of proteome research.

Moderate alcohol consumption is associated with improved insulin sensitivity, reduced basal insulin secretion rate and lower fasting glucagon concentration in healthy women

F. T. E. Group, E. Disse, K. Højlund, 2012, Diabetologia.

In human nephrectomy specimens, the kidney level of tubular transport proteins does not correlate with their abundance in urinary extracellular vesicles.

K. Højlund, K. Skjødt, H. Dimke, 2019, American journal of physiology. Renal physiology.

Markers of autophagy are adapted to hyperglycaemia in skeletal muscle in type 2 diabetes

K. Højlund, B. Vind, S. J. Petersson, 2015, Diabetologia.

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

H. Hakonarson, Cecilia Kim, S. Grant, 2018, Diabetes Care.

Impact of objectively measured sedentary behaviour on changes in insulin resistance and secretion over 3 years in the RISC study: interaction with weight gain.

B. Balkau, B. Heude, J. Dekker, 2013, Diabetes & metabolism.

Effect of Calorie-Unrestricted Low-Carbohydrate, High-Fat Diet Versus High-Carbohydrate, Low-Fat Diet on Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

J. Brønd, K. Højlund, H. Beck-Nielsen, 2022, Annals of Internal Medicine.

Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes

K. Højlund, H. Beck-Nielsen, J. Frystyk, 2006, Diabetologia.

Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle

Bente Kiens, Maximilian Kleinert, Peter Schjerling, 2013, Diabetes.

Mitochondrial Respiration Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes

K. Sahlin, K. Højlund, H. Beck-Nielsen, 2007, Diabetes.

Impaired Insulin-Stimulated Phosphorylation of Akt and AS160 in Skeletal Muscle of Women With Polycystic Ovary Syndrome Is Reversed by Pioglitazone Treatment

K. Højlund, H. Beck-Nielsen, J. Wojtaszewski, 2008, Diabetes.

Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation

M. Walker, C. Relton, K. Højlund, 2019, Diabetes research and clinical practice.

Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein*

L. Mandarino, R. Rafikov, K. Højlund, 2017, Molecular & Cellular Proteomics.

University of Southern Denmark Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein Sørensen,

L. Mandarino, R. Rafikov, K. Højlund, 2017 .

The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes

J. W. Dietrich, Johannes W. Dietrich, H. Klein, 2012, Diabetologia.

Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary Syndrome

Mihaela M. Martis, C. Ling, K. Højlund, 2018, The Journal of clinical endocrinology and metabolism.

Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

S. Knudsen, K. Højlund, H. Beck-Nielsen, 2007, Diabetes.

Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.

K. Højlund, M. Andersen, S. J. Petersson, 2014, European journal of endocrinology.

Effect of Exercise Training on Fat Loss—Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution

K. Højlund, Jørgen Jensen, K. J. Kolnes, 2021, Frontiers in Physiology.

Identification of the Oxidized Low-Density Lipoprotein Scavenger Receptor CD36 in Plasma: A Novel Marker of Insulin Resistance

K. Højlund, H. Beck-Nielsen, A. Handberg, 2006, Circulation.

Gene-environment interactions in the associations of PFAS exposure with insulin sensitivity and beta-cell function in a Faroese cohort followed from birth to adulthood.

B. Coull, D. Christiani, K. Audouze, 2023, Environmental research.

Endogenous glucose production increases in response to metformin treatment in the glycogen-depleted state in humans: a randomised trial

K. Højlund, H. Beck-Nielsen, O. Hother-Nielsen, 2015, Diabetologia.

Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers

K. Højlund, H. Beck-Nielsen, O. Hother-Nielsen, 2015, European Journal of Clinical Pharmacology.

Osteoprotegerin Levels Decrease During Testosterone Therapy in Aging Men and are Associated with Changed Distribution of Regional Fat

K. Højlund, D. Glintborg, M. Andersen, 2012, Hormone and Metabolic Research.

Testosterone therapy increased muscle mass and lipid oxidation in aging men

D. Hougaard, K. Højlund, M. Andersen, 2011, AGE.

Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes

K. Sahlin, K. Højlund, F. Dela, 2010, Diabetologia.

Euglycemic Clamp Insulin Sensitivity and Longitudinal Systolic Blood Pressure: Role of Sex

B. Balkau, Z. Pataky, E. Ferrannini, 2013, Hypertension.

Impact of objectively measured sedentary behaviour on changes in insulin resistance and secretion over three years: interaction with weight gain. The RISC Study.

B. Balkau, B. Heude, J. Dekker, 2012 .

Exercise induction of key transcriptional regulators of metabolic adaptation in muscle is preserved in type 2 diabetes.

K. Højlund, J. Wojtaszewski, R. Sabaratnam, 2019, The Journal of clinical endocrinology and metabolism.

Five-Year Incidence of Proliferative Diabetic Retinopathy and Associated Risk Factors in a Nationwide Cohort of 201 945 Danish Patients with Diabetes.

T. R. Savarimuthu, T. Peto, J. Grauslund, 2023, Ophthalmology science.

Beta-cell function is associated with carotid intima-media thickness independently of insulin resistance in healthy individuals

B. Balkau, M. Kozáková, R. Roussel, 2016, Journal of hypertension.

Depressive symptoms, insulin sensitivity and insulin secretion in the RISC cohort study.

F. Pouwer, B. Balkau, J. Dekker, 2013, Diabetes & metabolism.

Factors mediating exercise‐induced organ crosstalk

K. Højlund, R. Sabaratnam, J. Wojtaszewski, 2022, Acta physiologica.

Acute exercise increases plasma levels of muscle-derived microvesicles carrying fatty acid transport proteins.

K. Højlund, A. Handberg, R. Sabaratnam, 2019, The Journal of clinical endocrinology and metabolism.

Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

T. Hansen, O. Pedersen, N. Grarup, 2013, BMC Medical Genetics.

Accelerometer-derived physical activity and sedentary behaviors in individuals with newly diagnosed type 2 diabetes: A cross-sectional study from the Danish nationwide DD2 cohort

A. Grøntved, J. Tarp, J. Brønd, 2023, Frontiers in Sports and Active Living.

Personalized phosphoproteomics identifies functional signaling

Sean J. Humphrey, D. James, K. Højlund, 2021, Nature Biotechnology.

Dysregulation of muscle glycogen synthase in recovery from exercise in type 2 diabetes

K. Højlund, J. Wojtaszewski, M. Friedrichsen, 2015, Diabetologia.

Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study

K. Højlund, B. Bytoft, S. Knorr, 2017, Diabetologia.

A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance

K. Højlund, H. Beck-Nielsen, J. Wojtaszewski, 2014, Diabetologia.

Effects of insulin and exercise training on FGF21, its receptors and target genes in obesity and type 2 diabetes

K. Højlund, S. Vienberg, B. Vind, 2017, Diabetologia.

transcriptional regulators of metabolic adaptation in muscle is preserved in type 2 diabetes

K. Højlund, J. Wojtaszewski, R. Sabaratnam, 2019 .

Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes

K. Højlund, J. Wojtaszewski, A. Handberg, 2018, Physiological reports.

Syddansk Universitet Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes

K. Højlund, J. Wojtaszewski, A. Handberg, 2018 .

Insulin Sensitivity and Albuminuria: The RISC Study

B. Balkau, G. Nijpels, J. Dekker, 2014, Diabetes Care.

Low Bone Turnover Associates with Lower Insulin Sensitivity in Newly Diagnosed Drug-naïve Persons with Type 2 Diabetes.

R. Eastell, M. Frost, K. Højlund, 2023, Journal of Clinical Endocrinology and Metabolism.

40th EASD Annual Meeting of the European Association for the Study of Diabetes

B. M. Rasmussen, A. M. Foster, S. Bandinelli, 2004, Diabetologia.

Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort

I. Brandslund, C. Ling, A. Vaag, 2022, BMJ Open Diabetes Research & Care.

Autonomic nervous system activation mediates the increase in whole‐body glucose uptake in response to electroacupuncture

C. Behre, K. Højlund, E. Stener-Victorin, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Presence and development of diabetic retinopathy in 153 238 patients with type 2 diabetes in the Danish Registry of Diabetic Retinopathy

J. Grauslund, R. Kawasaki, T. Bek, 2022, Acta ophthalmologica.

Renal function markers and insulin sensitivity after 3 years in a healthy cohort, the EGIR-RISC study

B. Balkau, J. Dekker, Z. Massy, 2018, BMC Nephrology.

Changes in HbA1c and circulating and adipose tissue androgen levels in overweight‐obese women with polycystic ovary syndrome in response to electroacupuncture

C. Behre, C. Ohlsson, K. Højlund, 2016, Obesity science & practice.

Syddansk Universitet Changes in HbA 1 c and circulating and adipose tissue androgen levels in overweight-obese women with polycystic ovary syndrome in response to electroacupuncture

C. Behre, C. Ohlsson, K. Højlund, 2016 .

Genome-wide association study and functional characterisation identifies candidate genes for insulin-stimulated glucose uptake

C. Gieger, N. Grarup, C. Lindgren, 2023, Nature Genetics.

Maximal lipid oxidation in patients with type 2 diabetes is normal and shows an adequate increase in response to aerobic training

K. Sahlin, K. Højlund, H. Beck-Nielsen, 2009, Diabetes, obesity & metabolism.

Lipid droplets and their role in the development of insulin resistance and diabetic dyslipidemia

J. Borén, K. Højlund, Rosie Perkins, 2009 .

Altered intramuscular network of lipid droplets and mitochondria in type 2 diabetes.

K. Højlund, N. Ørtenblad, J. Nielsen, 2022, American journal of physiology. Cell physiology.

Acute exercise increases the contact between lipid droplets and mitochondria independently of obesity and type 2 diabetes

K. Højlund, N. Ørtenblad, J. Nielsen, 2023, The Journal of physiology.

Diabetic retinopathy as a potential marker of Parkinson’s disease: a register-based cohort study

J. Grauslund, R. Kawasaki, S. Möller, 2021, Brain communications.

University of Southern Denmark In human nephrectomy specimens, the kidney level of tubular transport proteins does not correlate with their abundance in urinary extracellular vesicles Sabaratnam,

K. Højlund, K. Skjødt, H. Dimke, 2019 .

Diabetic Retinopathy Predicts Risk of Alzheimer’s Disease: A Danish Registry-Based Nationwide Cohort Study

F. Pouwer, T. Peto, J. Grauslund, 2022, Journal of Alzheimer's disease : JAD.

Mitochondria, glycogen, and lipid droplets in skeletal muscle during testosterone treatment and strength training: a randomized, double‐blinded, placebo‐controlled trial

K. Højlund, T. Kvorning, D. Glintborg, 2018, Andrology.

The assembly of lipid droplets and its relation to cellular insulin sensitivity.

J. Borén, K. Højlund, Rosie Perkins, 2009, Biochemical Society transactions.

Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes

A. Vaag, K. Højlund, M. Olsen, 2023, Diabetologia.

Diabetic retinopathy is a predictor of chronic respiratory failure: A nationwide register-based cohort study

J. Grauslund, T. Bek, K. Højlund, 2023, Heliyon.

Acupuncture increases whole body glucose uptake during and after stimulation in women with polycystic ovary syndrome

C. Behre, K. Højlund, E. Stener-Victorin, 2014 .

Longitudinal bidirectional associations between diabetic retinopathy and diagnosed depression: Results from a Danish nationwide registry-based cohort study.

F. Pouwer, T. Peto, J. Grauslund, 2023, Journal of diabetes and its complications.

Bidirectional 5‐year risks of diabetic retinopathy, glaucoma and/or ocular hypertension: Results from a national screening programme

Kenneth H. Rubin, J. Grauslund, T. Bek, 2022, Acta ophthalmologica.

Inverse Cross-sectional and Longitudinal Relationships between Diabetic Retinopathy and Obstructive Sleep Apnea in Type 2 Diabetes

Kenneth H. Rubin, M. Rasmussen, J. Grauslund, 2021, Ophthalmology science.

Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

T. Hansen, O. Pedersen, N. Grarup, 2012, Diabetologia.

A six-month low-carbohydrate diet high in fat does not adversely affect endothelial function or markers of low-grade inflammation in patients with type 2 diabetes: an open-label randomized controlled trial

K. Højlund, H. Beck-Nielsen, A. Handberg, 2023, Cardiovascular Diabetology.

Serum sclerostin and glucose homeostasis: No association in healthy men. Cross-sectional and prospective data from the EGIR-RISC study.

P. Nilsson, B. Balkau, E. Ferrannini, 2020, Bone.

Effects of DPP‐4 inhibitors, GLP‐1 receptor agonists, SGLT‐2 inhibitors and sulphonylureas on mortality, cardiovascular and renal outcomes in type 2 diabetes: A network meta‐analyses‐driven approach

M. Christensen, K. Højlund, E. Søndergaard, 2023, Diabetic medicine : a journal of the British Diabetic Association.

Plasma FGF21 displays a circadian rhythm during a 72‐h fast in healthy female volunteers

Birgitte Andersen, K. Højlund, H. Beck-Nielsen, 2011, Clinical endocrinology.

Bariatric surgery in individuals with type 2 diabetes is not associated with short or long-term risk of diabetic retinopathy progression: results from a nationwide cohort study

J. Grauslund, T. Bek, K. Højlund, 2023, Acta Diabetologica.

In vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.

C. Flynn, L. Mandarino, B. Bowen, 2009, Journal of proteome research.

Beta-cell function is associated with carotid intima-media thickness independently of insulin resistance in healthy individuals

B. Balkau, M. Kozáková, R. Roussel, 2016, Journal of hypertension.

High-throughput proteomics uncovers exercise training and type 2 diabetes–induced changes in human white adipose tissue

K. Højlund, N. Ørtenblad, J. K. Larsen, 2023, Science advances.

Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.

K. Højlund, M. Andersen, S. J. Petersson, 2014, European journal of endocrinology.

Retinal microvascular markers in type 2 diabetes subphenotypes and latent autoimmune diabetes of adults

J. Grauslund, K. Højlund, M. Olsen, 2023, Acta ophthalmologica.

Metabolic risk profiles in diabetes stratified according to age at onset, islet autoimmunity and fasting C-peptide.

K. Højlund, H. Beck-Nielsen, M. Wod, 2016, Diabetes research and clinical practice.

Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers

K. Højlund, H. Beck-Nielsen, O. Hother-Nielsen, 2015, European Journal of Clinical Pharmacology.

Mutation in the Human Insulin Receptor Gene A Novel Syndrome of Autosomal-Dominant Hyperinsulinemic Hypoglycemia Linked to a

Christopher J. Davidson, O. Pedersen, T. Zderic, 2015 .

Inter‐grader reliability in the Danish screening programme for diabetic retinopathy

T. Peto, J. Grauslund, T. Bek, 2023, Acta ophthalmologica.

Increased subsarcolemmal lipids in type 2 diabetes: effect of training on localization of lipids, mitochondria, and glycogen in sedentary human skeletal muscle.

K. Sahlin, K. Højlund, B. Vind, 2010, American journal of physiology. Endocrinology and metabolism.