R. Okada

Y. Shinohara, K. Wakai, R. Okada, 2020, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Metallothionein MT2A A-5G Polymorphism as a Risk Factor for Chronic Kidney Disease and Diabetes: Cross-Sectional and Cohort Studies

N. Hamajima, K. Wakai, R. Okada, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Elevated Serum Lipase Levels as a Marker of Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Cross-Sectional Study

K. Wakai, R. Okada, Takashi Okada, 2020 .

The number of metabolic syndrome components is a good risk indicator for both early- and late-stage kidney damage.

N. Hamajima, K. Wakai, R. Okada, 2014, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Matrix Metalloproteinase-9 Gene Polymorphisms and Chronic Kidney Disease

M. Kubo, N. Kuriyama, N. Hamajima, 2012, American Journal of Nephrology.

Glomerular hyperfiltration in prediabetes and prehypertension.

N. Hamajima, K. Wakai, R. Okada, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-cholesterol Levels in J-MICC Study Participants

M. Kubo, K. Matsuo, Hidemi Ito, 2021, Journal of epidemiology.

Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018

Yusuke Suzuki, Tetsuhiro Tanaka, M. Nangaku, 2018, Clinical and Experimental Nephrology.

PREVALENCE OF HELICOBACTER PYLORI INFECTION MEASURED WITH URINARY ANTIBODY IN AN URBAN AREA OF JAPAN, 2008–2010

N. Hamajima, K. Wakai, R. Okada, 2012, Nagoya journal of medical science.

A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population: the J-MICC Study

M. Kubo, N. Hamajima, Hideo Tanaka, 2014, Endocrine.

Associations of metabolic syndrome and metabolically unhealthy obesity with cancer mortality: The Japan Multi-Institutional Collaborative Cohort (J-MICC) study

K. Matsuo, K. Wakai, S. Katsuura-Kamano, 2022, PloS one.

ASSOCIATION OF OBESITY AND DIABETES WITH SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS IN JAPANESE MALES

N. Hamajima, A. Tamakoshi, K. Wakai, 2012, Nagoya journal of medical science.

Profile of Participants and Genotype Distributions of 108 Polymorphisms in a Cross-Sectional Study of Associations of Genotypes With Lifestyle and Clinical Factors: A Project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study

M. Kubo, K. Matsuo, Hidemi Ito, 2011, Journal of Epidemiology.

Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: a cross-sectional study in postmenopausal Japanese women

M. Kubo, N. Kuriyama, N. Hamajima, 2017, British Journal of Nutrition.

Smoking and serum CA19‐9 levels according to Lewis and secretor genotypes

Y. Goto, N. Hamajima, K. Wakai, 2008, International Journal of Cancer.

Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer

M. Kubo, N. Hamajima, Hideo Tanaka, 2017, Gastric Cancer.

Common Variant of PDZK1, Adaptor Protein Gene of Urate Transporters, is Not Associated with Gout

N. Shinomiya, Y. Sakurai, R. Okada, 2014, The Journal of Rheumatology.

ASSOCIATIONS BETWEEN BODY MASS INDEX AND SERUM URIC ACID LEVELS IN A JAPANESE POPULATION WERE SIGNIFICANTLY MODIFIED BY LRP2 rs2544390

N. Hamajima, K. Wakai, R. Okada, 2014, Nagoya journal of medical science.

Not Associated with Gout Common Variant of PDZK 1 , Adaptor Protein Gene of Urate Transporters , is

Y. Sakurai, R. Okada, A. Nakayama, 2014 .

NO ASSOCIATION BETWEEN MTHFR C677T AND SERUM URIC ACID LEVELS AMONG JAPANESE WITH ABCG2 126QQ AND SLC22A12 258WW

N. Hamajima, K. Wakai, R. Okada, 2013, Nagoya journal of medical science.

Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population

N. Hamajima, K. Wakai, R. Okada, 2011, BMC Medical Genetics.

Associations of Genome-Wide Polygenic Risk Score and Risk Factors With Hypertension in a Japanese Population

M. Kubo, Y. Momozawa, K. Wakai, 2022, Circulation. Genomic and precision medicine.

Controls for monitoring the deterioration of stored blood samples in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study).

N. Hamajima, A. Tamakoshi, K. Wakai, 2008, Nagoya journal of medical science.

A genome-wide association study on adherence to low-carbohydrate diets in Japanese

M. Kubo, Hidemi Ito, Y. Momozawa, 2022, European Journal of Clinical Nutrition.

Modification of the effect of smoking on cholesterol in Japanese carriers of a PTPN11 polymorphism.

Y. Goto, N. Hamajima, K. Wakai, 2008, Molecular medicine reports.

Irregular sleep and all-cause mortality: A large prospective cohort study.

K. Matsuo, H. Kadotani, Yohko Nakamura, 2022, Sleep health.

Association of UGT1A1 Gly71Arg with urine urobilinogen.

N. Hamajima, K. Wakai, R. Okada, 2011, Nagoya journal of medical science.

Effects of IL6 C-634G polymorphism on tooth loss and their interaction with smoking habits.

N. Hamajima, K. Wakai, R. Okada, 2015, Oral diseases.

Bone marrow transplant nephropathy successfully treated with angiotensin-converting enzyme inhibitor

Y. Yuzawa, R. Okada, M. Kasai, 2006, Clinical and Experimental Nephrology.

Severe brain atrophy in the elderly as a risk factor for lower respiratory tract infection

G. Sobue, N. Hamajima, R. Okada, 2012, Clinical interventions in aging.

No association between the frequency of forest walking and blood pressure levels or the prevalence of hypertension in a cross-sectional study of a Japanese population

N. Hamajima, K. Wakai, R. Okada, 2011, Environmental health and preventive medicine.

Elevated Serum Lipase Levels in Patients with Dyspepsia of Unknown Cause in General Practice

Tohru Okada, N. Hamajima, R. Okada, 2009, Medical Principles and Practice.

A Function-Based Genetic Analysis in a Japanese Population Common Defects of ABCG 2 , a High-Capacity Urate Exporter , Cause Gout :

N. Hamajima, K. Wakai, N. Shinomiya, 2010 .

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

N. Hamajima, K. Wakai, N. Shinomiya, 2009, Science Translational Medicine.

Multiple common and rare variants of ABCG2 cause gout

T. Merriman, K. Wakai, N. Shinomiya, 2017, RMD Open.

A genome-wide association study on fish consumption in a Japanese population—the Japan Multi-Institutional Collaborative Cohort study

M. Kubo, K. Matsuo, Hidemi Ito, 2020, European Journal of Clinical Nutrition.

Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study

M. Kubo, K. Matsuo, Hidemi Ito, 2020, Journal of epidemiology.

Associations between peroxisome proliferator-activated receptor γ (PPAR-γ) polymorphisms and serum lipids: two cross-sectional studies of community-dwelling adults.

N. Hamajima, K. Wakai, R. Okada, 2020, Gene.

BMI and Cardiometabolic Traits in Japanese: A Mendelian Randomization Study

Y. Momozawa, Yohko Nakamura, K. Wakai, 2023, Journal of epidemiology.

Incidence of Fever of Unknown Origin and Subsequent Antitubercular Medications in Hemodialysis Patients: A Two-Year Prospective Study

N. Hamajima, T. Kawamura, Y. Yuzawa, 2009, Renal failure.

Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study

Y. Kamatani, M. Kubo, Hidemi Ito, 2018, American Journal of Nephrology.

Anti-Helicobacter pylori antibody status is associated with cancer mortality: A longitudinal analysis from the Japanese DAIKO prospective cohort study

S. Nishizuka, K. Wakai, Y. Sutoh, 2023, PLOS global public health.

DPP4 GENETIC VARIANTS INFLUENCE BASELINE PROSTATE-SPECIFIC ANTIGEN LEVELS: THE J-MICC STUDY

N. Hamajima, K. Wakai, R. Okada, 2013, Nagoya journal of medical science.

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

M. Kanai, Y. Kamatani, Y. Okada, 2019, Communications Biology.

New prognostic factors and scoring system for patients with skeletal metastasis

R. Okada, H. Ogawa, H. Harada, 2014, Cancer medicine.

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

K. Matsuo, Y. Momozawa, Yohko Nakamura, 2023, Diabetology International.

Significant interaction between RETN -420 G/G genotype and lower BMI on decreased risk of type 2 diabetes mellitus (T2DM) in Japanese--the J-MICC Study.

M. Kubo, N. Hamajima, Hideo Tanaka, 2013, Endocrine journal.

A Genome-wide Association Study in the Diabetic Patients Finds the 13q35.43-35.46 Locus Associated with Estimated Glomerular Filtration Rate: The Japan Multi-Institutional Collaborative Cohort Study

M. Kubo, Hidemi Ito, N. Kuriyama, 2018 .

Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population.

A. Goto, M. Kubo, M. Nagasaki, 2019, Sleep.

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

Y. Kamatani, Y. Okada, T. Kawaguchi, 2020, Nature Communications.

Associations of breastfeeding history with metabolic syndrome and cardiovascular risk factors in community-dwelling parous women: The Japan Multi-Institutional Collaborative Cohort Study

Hidemi Ito, N. Kuriyama, Yohko Nakamura, 2022, PloS one.

Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study.

Yohko Nakamura, Y. Kita, K. Wakai, 2020, Alcohol.

Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men

M. Kubo, N. Kuriyama, N. Hamajima, 2015, Scientific Reports.

Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population.

N. Hamajima, K. Wakai, R. Okada, 2011, Molecular genetics and metabolism.

Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach

N. Shinomiya, R. Okada, A. Hishida, 2021, Human Cell.

Upper-normal waist circumference is a risk marker for metabolic syndrome in normal-weight subjects.

N. Hamajima, K. Wakai, R. Okada, 2016, Nutrition, metabolism, and cardiovascular diseases : NMCD.

A risk score predicting new incidence of hypertension in Japan

N. Hamajima, K. Wakai, R. Okada, 2019, Journal of Human Hypertension.

MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study

M. Kubo, N. Kuriyama, N. Hamajima, 2013, International Urology and Nephrology.

And Sels) and Risk of Chronic Kidney Disease in Japanese Crossssectional Data from the Jjmicc Study

M. Kubo, N. Hamajima, Hideo Tanaka, 2022 .

Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study.

M. Kubo, K. Matsuo, N. Hamajima, 2012, Endocrine journal.

Renal Hyperfiltration in Prediabetes Confirmed by Fasting Plasma Glucose and Hemoglobin A1c

N. Hamajima, K. Wakai, R. Okada, 2012, Renal failure.

Within-visit blood pressure variability is associated with prediabetes and diabetes

N. Hamajima, K. Wakai, R. Okada, 2015, Scientific Reports.

SLC22A12 W258X FREQUENCY ACCORDING TO SERUM URIC ACID LEVEL AMONG JAPANESE HEALTH CHECKUP EXAMINEES

N. Hamajima, R. Okada, M. Naito, 2011, Nagoya journal of medical science.

Association of exposure level to passive smoking with hypertension among lifetime nonsmokers in Japan: a cross-sectional study

Yohko Nakamura, Y. Kita, K. Wakai, 2018, Medicine.

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

M. Kanai, Y. Kamatani, Y. Okada, 2019, Communications Biology.

Massive pleural effusion induced by internal jugular vein catheterization for hemodialysis

Y. Yuzawa, R. Okada, Noritoshi Kato, 2004 .

Lower risk of progression from prediabetes to diabetes with health checkup with lifestyle education: Japan Ningen Dock study.

K. Wakai, R. Okada, Y. Ishizaka, 2017, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

K. Wakai, N. Shinomiya, Y. Sakurai, 2014, Scientific Reports.

Sex-specific Relationship Between Stress Coping Strategies and All-cause Mortality: Japan Multi-Institutional Collaborative Cohort Study

K. Matsuo, K. Wakai, S. Katsuura-Kamano, 2021, Journal of epidemiology.

Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of URAT1/SLC22A12 gene

N. Shinomiya, R. Okada, Y. Kubo, 2021, Rheumatology.

Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus

N. Shinomiya, R. Okada, S. Kawai, 2016, Scientific Reports.

Genetic Variants of RAMP2 and CLR are Associated with Stroke

M. Kubo, Hidemi Ito, N. Kuriyama, 2017, Journal of atherosclerosis and thrombosis.

Effect of Underlying Cardiometabolic Diseases on the Association Between Sedentary Time and All‐Cause Mortality in a Large Japanese Population: A Cohort Analysis Based on the J‐MICC Study

N. Kuriyama, Yohko Nakamura, H. Nagase, 2021, Journal of the American Heart Association.

Associations between diet and mental health using the 12-item General Health Questionnaire: cross-sectional and prospective analyses from the Japan Multi-Institutional Collaborative Cohort Study

N. Hamajima, K. Wakai, R. Okada, 2020, Nutrition Journal.

Study Profile of the Japan Multi-institutional Collaborative Cohort (J-MICC) Study

K. Matsuo, Hidemi Ito, Y. Momozawa, 2020, Journal of epidemiology.

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

M. Kanai, Y. Kamatani, Y. Okada, 2019, Communications Biology.

Trends in smoking rates among urban civil servants in Japan according to occupational categories

N. Hamajima, K. Wakai, R. Okada, 2015, Nagoya journal of medical science.

A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern

M. Kubo, K. Matsuo, Hidemi Ito, 2020, European Journal of Clinical Nutrition.

Dietary carbohydrate and fat intakes and risk of mortality in the Japanese population: the Japan Multi-Institutional Collaborative Cohort Study.

K. Matsuo, Hidemi Ito, Yohko Nakamura, 2023, The Journal of nutrition.

Helicobacter pylori infection reduces likelihood of death from advanced cancer: A longitudinal analysis from the Japanese DAIKO prospective cohort study

K. Wakai, Y. Sutoh, R. Okada, 2021, medRxiv.

STUDY PROFILE ON BASELINE SURVEY OF DAIKO STUDY IN THE JAPAN MULTI-INSTITUTIONAL COLLABORATIVE COHORT STUDY (J-MICC STUDY)

N. Hamajima, K. Wakai, R. Okada, 2011, Nagoya journal of medical science.

Frequency of forest walking is not associated with prevalence of hypertension based on cross-sectional studies of a general Japanese population: a reconfirmation by the J-MICC Daiko Study

K. Wakai, R. Okada, Y. Kubo, 2019, Nagoya journal of medical science.

Large-scale survey of frequency of forest walking and related factors in a Japanese population inhabiting a large city, and comparison of an urban area and a rural area

N. Hamajima, K. Wakai, R. Okada, 2013, Journal of Forest Research.

Baseline data of Shizuoka area in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study).

N. Hamajima, A. Tamakoshi, K. Wakai, 2009, Nagoya journal of medical science.

Alcohol dehydrogenase 1B and Aldehyde dehydrogenase 2 Polymorphisms in Uzbekistan.

K. Ahn, N. Hamajima, R. Okada, 2009, Asian Pacific journal of cancer prevention : APJCP.

Associations of smoking status with other lifestyle behaviors are modified by sex and occupational category among urban civil servants in Japan

N. Hamajima, K. Wakai, R. Okada, 2016, Environmental Health and Preventive Medicine.

Genome-wide association study of serum prostate-specific antigen levels based on 1000 Genomes imputed data in Japanese: the Japan Multi-Institutional Collaborative Cohort Study

M. Kubo, N. Kuriyama, Y. Momozawa, 2021, Nagoya journal of medical science.

Applicability of allele/genotype frequency from documented controls for case-control studies on genotypes among Japanese: MTHFR C677T as an example.

N. Hamajima, K. Wakai, R. Okada, 2009, Asian Pacific journal of cancer prevention : APJCP.

GWAS of Folate Metabolism With Gene–environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study

K. Matsuo, Y. Momozawa, N. Hamajima, 2023, Journal of epidemiology.

Association between the catechol-O-methyltransferase (rs4680: Val158Met) polymorphism and serum alanine aminotransferase activity.

K. Matsuo, N. Kuriyama, N. Hamajima, 2012, Gene.

Association of daily physical activity and leisure-time exercise with dysphagia risk in community-dwelling older adults: a cross-sectional study

K. Wakai, R. Okada, Y. Kubo, 2023, Scientific reports.

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

A. Takahashi, N. Hamajima, N. Shinomiya, 2015, Annals of the rheumatic diseases.

Association between KLK3 rs2735839 G/A Polymorphism and Serum PSA Levels in Japanese Men

N. Hamajima, K. Wakai, R. Okada, 2012, Urologia Internationalis.

Visit-to-visit blood pressure variability is a marker of cardiac diastolic function and carotid atherosclerosis

K. Wakai, R. Okada, M. Nanasato, 2014, BMC Cardiovascular Disorders.

Common Variant of PDZK1, Adaptor Protein Gene of Urate Transporters, is Not Associated with Gout

N. Shinomiya, Y. Sakurai, R. Okada, 2014, The Journal of Rheumatology.

Seven‐plus hours of daily sedentary time and the subsequent risk of breast cancer: Japan Multi‐Institutional Collaborative Cohort Study

Hidemi Ito, K. Arisawa, R. Okada, 2023, Cancer science.

Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study

S. Katsuura-Kamano, K. Arisawa, R. Okada, 2024, Public Health Nutrition.