B. Corkey

发表

Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study

C. Apovian, H. Cabral, Liqun Yu, 2019, PloS one.

Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation.

B. Corkey, D. Song, Lisa Getty-Kaushik, 2007, Gastroenterology.

Mitochondrial Networking Protects Beta Cells from Nutrient Induced Apoptosis

B. Corkey, J. Wikstrom, A. Molina, 2009 .

Chronic Exposure to Excess Nutrients Left-shifts the Concentration Dependence of Glucose-stimulated Insulin Secretion in Pancreatic β-Cells*

N. Burritt, J. Deeney, B. Corkey, 2015, The Journal of Biological Chemistry.

Lipid-associated metabolic signalling networks in pancreatic beta cell function

M. Prentki, B. Corkey, S. Madiraju, 2019, Diabetologia.

Fatty acid metabolism and insulin secretion in pancreatic beta cells

B. Corkey, G. Yaney, 2003, Diabetologia.

[65] Assays of intermediates of the citric acid cycle and related compounds by fluorometric enzyme methods

B. Corkey, J. Williamson, 1969 .

Induction by Glucose of Genes Coding for Glycolytic Enzymes in a Pancreatic β-Cell Line (INS-1)*

M. Prentki, B. Corkey, E. Roche, 1997, The Journal of Biological Chemistry.

Cohort profile: The MULTI sTUdy Diabetes rEsearch (MULTITUDE) consortium

R. Vasan, L. Moore, B. Corkey, 2018, BMJ Open.

Octanoate attenuates adipogenesis in 3T3-L1 preadipocytes.

B. Corkey, S. Farmer, Y. Ido, 2002, The Journal of nutrition.

The Redox Communication Network as a Regulator of Metabolism

J. Deeney, B. Corkey, 2020, Frontiers in Physiology.

Metabolomics‐guided insights on bariatric surgery versus behavioral interventions for weight loss

F. Tinahones, B. Corkey, C. Andrés-Lacueva, 2016, Obesity.

Banting Lecture 2011

B. Corkey, 2011, Diabetes.

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets.

D. Tillotson, M. Prentki, J. Deeney, 1991, The Journal of biological chemistry.

Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation.

B. Corkey, J. Hamilton, Jianrong Han, 2004, Obesity research.

Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate.

B. Corkey, J. Hamilton, J. Kirkland, 2000, The Biochemical journal.

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.

M. Andersen, C. Woods, Qiang Zhang, 2010, Toxicology and applied pharmacology.

β-Cell Failure or β-Cell Abuse?

B. Corkey, K. Erion, 2018, Front. Endocrinol..

The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema

S. Grant, B. Corkey, S. Epstein, 2016, Diabetes Care.

Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose.

O. Shirihai, J. Deeney, B. Corkey, 2007, The Biochemical journal.

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells.

B. Corkey, P. Berggren, K. Tornheim, 1996, The Biochemical journal.

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.

M. Prentki, B. Corkey, V. Schulz, 2000, Diabetes.

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior.

M. Köhler, J. Deeney, B. Corkey, 2001, The Journal of biological chemistry.

Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes*

B. Corkey, P. Pilch, F. Kamp, 2003, The Journal of Biological Chemistry.

Current Views of the Fat Cell as an Endocrine Cell: Lipotoxicity

B. Corkey, J. Kirkland, T. Tchkonia, 2006 .

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

S. R. Datta, M. Greenberg, S. Korsmeyer, 2008, Nature Medicine.

What Are We Putting in Our Food That Is Making Us Fat? Food Additives, Contaminants, and Other Putative Contributors to Obesity

B. Corkey, J. Schlezinger, A. Simmons, 2014, Current Obesity Reports.

Oleate-induced formation of fat cells with impaired insulin sensivitity

B. Corkey, J. Hamilton, J. Kirkland, 2006, Lipids.

Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects.

B. Corkey, Jing Ma, J. Kirkland, 2007, Metabolism: clinical and experimental.

Self-report-based estimates of energy intake offer an inadequate basis for scientific conclusions.

Kevin D Hall, David B Allison, Eric Ravussin, 2013, The American journal of clinical nutrition.

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes.

B. Corkey, J. Hill, J. McGarry, 1997, The Biochemical journal.

Long-Chain Fatty Acids Inhibit Acetyl-CoA Carboxylase Gene Expression in the Pancreatic β-Cell Line INS-1

M. Prentki, B. Corkey, Thierry Brun, 1997, Diabetes.

Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

M. Prentki, G. Mitchell, B. Corkey, 2004, Diabetes.

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells.

M. Prentki, J. Deeney, B. Corkey, 1989, The Journal of biological chemistry.

β-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels

N. Danial, O. Shirihai, B. Corkey, 2007, Diabetes.

Beta-Mecaptoethanol Suppresses Inflammation and Induces Adipogenic Differentiation in 3T3-F442A Murine Preadipocytes

C. Apovian, B. Corkey, J. Kirkland, 2012, PloS one.

Metabolic Regulation of Ca 2+ Handling in Permeabilized Insulinoma Cells

M. Prentki, N. Ruderman, J. Deeney, 1989 .

Cysteine string protein (CSP) is an insulin secretory granule‐associated protein regulating β‐cell exocytosis

R. Scheller, O. Larsson, J. Deeney, 1998, The EMBO journal.

Reversible Ca2+-dependent Translocation of Protein Kinase C and Glucose-induced Insulin Release*

S. Chheda, J. Deeney, B. Corkey, 1996, The Journal of Biological Chemistry.

Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.

M. Prentki, J. Deeney, B. Corkey, 2005, American journal of physiology. Endocrinology and metabolism.

Long Chain Coenzyme A Esters Activate the Pore-forming Subunit (Kir6.2) of the ATP-regulated Potassium Channel*

O. Larsson, B. Corkey, P. Berggren, 1998, The Journal of Biological Chemistry.

Activation of the ATP-sensitive K Channel by Long Chain Acyl-CoA

O. Larsson, J. Deeney, B. Corkey, 1996, The Journal of Biological Chemistry.

Type 1 diabetes alters lipid handling and metabolism in human fibroblasts and peripheral blood mononuclear cells

Devin W. Steenkamp, J. Deeney, B. Corkey, 2017, PloS one.

Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT).

J. Deeney, B. Corkey, K. Tornheim, 1996, The American journal of physiology.

Ca2+ responses to interleukin 1 and tumor necrosis factor in cultured human skin fibroblasts. Possible implications for Reye syndrome.

J. Deeney, B. Corkey, S. Douglas, 1991, The Journal of clinical investigation.

Hepatic metabolic alterations in rats treated with low-dose endotoxin and aspirin: an animal model of Reye's syndrome.

R. Polin, B. Corkey, S. Douglas, 1989, Metabolism: clinical and experimental.

Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis

O. Shirihai, B. Corkey, K. Trudeau, 2017, EMBO reports.

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

Yaguang Si, O. Shirihai, B. Corkey, 2014, The EMBO journal.

β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake

B. Lowell, B. Corkey, J. Himms-Hagen, 1997, The Journal of Biological Chemistry.

Beta3-adrenergic receptors on white and brown adipocytes mediate beta3-selective agonist-induced effects on energy expenditure, insulin secretion, and food intake. A study using transgenic and gene knockout mice.

B. Lowell, B. Corkey, J. Himms-Hagen, 1997, The Journal of biological chemistry.

Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling

Ajit S. Divakaruni, A. Petcherski, M. Prentki, 2020, EMBO reports.

Blocking mitochondrial pyruvate import causes energy wasting via futile lipid cycling in brown fat

Ajit S. Divakaruni, A. Petcherski, M. Prentki, 2019, bioRxiv.

Assay of short-chain acyl coenzyme A intermediates in tissue extracts by high-pressure liquid chromatography.

J. Williamson, B. Corkey, R. Williams, 1981, Analytical biochemistry.

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

O. Shirihai, J. Deeney, B. Corkey, 2009, Obesity.

Metabolic cycles and signals for insulin secretion.

M. Prentki, R. Kibbey, B. Corkey, 2022, Cell metabolism.

Effects of thiol antioxidant β-mercaptoethanol on diet-induced obese mice.

B. Corkey, J. Hamilton, J. Kirkland, 2014, Life sciences.

Metabolic control of -cell function

M. Prentki, J. Deeney, B. Corkey, 2000 .

Increased β-Oxidation in Muscle Cells Enhances Insulin-stimulated Glucose Metabolism and Protects against Fatty Acid-induced Insulin Resistance Despite Intramyocellular Lipid Accumulation*

B. Corkey, S. Adams, S. Commerford, 2004, Journal of Biological Chemistry.

Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells

B. Corkey, J. Hamilton, J. Kirkland, 1999, Lipids.

Interactions between alpha-ketoisovalerate metabolism and the pathways of gluconeogenesis and urea synthesis in isolated hepatocytes.

B. Corkey, J. Williamson, S. Cerdán, 1983, The Journal of biological chemistry.

Hexose transport in normal and SV40‐transformed human endothelial cells in culture

M. Gimbrone, B. Corkey, R. Corkey, 1981, Journal of cellular physiology.

Assay of citric acid cycle intermediates and related compounds--update with tissue metabolite levels and intracellular distribution.

B. Corkey, J. Williamson, 1979, Methods in enzymology.

The Intra- or Extracellular Redox State Was Not Affected by a High vs. Low Glycemic Response Diet in Mice

B. Corkey, Siu Wong, A. Kleckner, 2015, PloS one.

Metabolic Regulation of Insulin Secretion

B. Corkey, 2008 .

Evidence for a Unique Long Chain Acyl-CoA Ester Binding Site on the ATP-regulated Potassium Channel in Mouse Pancreatic Beta Cells*

O. Larsson, B. Corkey, P. Berggren, 1997, The Journal of Biological Chemistry.

Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets.

B. Corkey, J. Mccormack, E. A. Longo, 1990, The Biochemical journal.

Reactive Oxygen Species Facilitate Translocation of Hormone Sensitive Lipase to the Lipid Droplet During Lipolysis in Human Differentiated Adipocytes

Thomas C. Ferrante, B. Corkey, R. Zoeller, 2012, PloS one.

Reactive Oxygen Species Stimulate Insulin Secretion in Rat Pancreatic Islets: Studies Using Mono-Oleoyl-Glycerol

Thomas C. Ferrante, O. Shirihai, J. Deeney, 2012, PloS one.

Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids

J. Leahy, B. Corkey, H. Hosokawa, 1997, Diabetologia.

The Extracellular Redox State Modulates Mitochondrial Function, Gluconeogenesis, and Glycogen Synthesis in Murine Hepatocytes

B. Corkey, M. Liesa, A. Kleckner, 2015, PloS one.

Phosphofructokinase Isozymes in Pancreatic Islets and Clonal β-Cells (INS-1)

B. Corkey, K. Tornheim, G. Yaney, 1995, Diabetes.

Dehydroepiandrosterone Sulfate and-Cell Function Enhanced Glucose-Induced Insulin Secretion and Altered Gene Expression in Rodent Pancreatic-Cells

M. Prentki, D. Waxman, B. Corkey, 2000 .

A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.

B. Wicksteed, B. Corkey, C. Rhodes, 1998, The Biochemical journal.

Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression.

M. Prentki, B. Corkey, E. Roche, 1998, Diabetes.

Octanoate inhibits triglyceride synthesis in 3T3-L1 and human adipocytes.

B. Corkey, Jianrong Han, Wen Guo, 2003, The Journal of nutrition.

Biochemical and Molecular Actions of Nutrients Octanoate Inhibits Triglyceride Synthesis in 3 T 3L 1 and Human Adipocytes 1

B. Corkey, Jianrong Han, Wen Guo, 2003 .

Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets.

J. Deeney, B. Corkey, K. Tornheim, 2003, The Biochemical journal.

Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration

J. Locasale, L. Rameh, J. Deeney, 2020, iScience.

CYTOKINES INHIBIT FATTY ACID OXIDATION IN ISOLATED RAT HEPATOCYTES: SYNERGY AMONG TNF, IL‐6, AND IL‐1

B. Corkey, V. Nachiappan, L. Kilpatrick, 1994, Shock.

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A.

B. Corkey, O. Rosen, W. Phillips, 1991, The Journal of biological chemistry.

Glucagon-Like Peptide 1 Stimulates Lipolysis in Clonal Pancreatic β-Cells (HIT)

J. Deeney, B. Corkey, K. Tornheim, 2001 .

The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.

M. Prentki, J. Deeney, B. Corkey, 2000, The Journal of nutrition.

Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation.

B. Wicksteed, M. Prentki, B. Corkey, 2002, Diabetes.

Evidence for an Anaplerotic/Malonyl-CoA Pathway in Pancreatic β-Cell Nutrient Signaling

M. Prentki, B. Corkey, K. Kim, 1996, Diabetes.

Phosphofructokinase isozymes in pancreatic islets and clonal beta-cells (INS-1).

B. Corkey, K. Tornheim, G. Yaney, 1995, Diabetes.

Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).

J. Deeney, B. Corkey, K. Tornheim, 2001, Diabetes.

Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Children with Non-Ketotic Hypoglycemia and Low Carnitine Levels

C. Stanley, D. Hale, B. Corkey, 1983, Pediatric Research.

Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic beta-cells (HIT).

J. Deeney, B. Corkey, K. Tornheim, 1996, The Biochemical journal.

Glucose-induced Toxicity in Insulin-producing Pituitary Cells That Coexpress GLUT2 and Glucokinase

R. Mulligan, B. Corkey, M. Lipes, 2001, The Journal of Biological Chemistry.

Regulation of the branched chain alpha-ketoacid pathway in liver.

B. Corkey, J. Williamson, Á. Martín-Requero, 1982, The Journal of biological chemistry.

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

M. Prentki, J. Deeney, B. Corkey, 1996, The Biochemical journal.

Inositol 1,4,5-trisphosphate and the endoplasmic reticulum Ca2+ cycle of a rat insulinoma cell line.

M. Prentki, B. Corkey, F. Matschinsky, 1985, The Journal of biological chemistry.

Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion

M. Andersen, Qiang Zhang, J. Pi, 2007, Diabetes.

Metabolic control of beta-cell function.

M. Prentki, J. Deeney, B. Corkey, 2000, Seminars in cell & developmental biology.

Glucose-stimulated increase in cytoplasmic pH precedes increase in free Ca2+ in pancreatic beta-cells. A possible role for pyruvate.

B. Corkey, P. Berggren, K. Tornheim, 1994, The Journal of biological chemistry.

Acute Carbohydrate Overfeeding: A Redox Model of Insulin Action and Its Impact on Metabolic Dysfunction in Humans.

C. Apovian, Liqun Yu, T. Meshulam, 2021, American journal of physiology. Endocrinology and metabolism.

Cytosolic free calcium in adipocytes. Distinct mechanisms of regulation and effects on insulin action.

J. Deeney, B. Corkey, K. Kelly, 1989, The Journal of biological chemistry.

Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.

M. Prentki, D. Waxman, B. Corkey, 2000, Diabetes.

Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT).

M. Prentki, B. Corkey, M. Hiriart, 1989, Biochimica et biophysica acta.

Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet.

K. Williams, J. Deeney, B. Corkey, 1994, The Journal of biological chemistry.

Determination of the matrix free Ca2+ concentration and kinetics of Ca2+ efflux in liver and heart mitochondria.

B. Corkey, J. Williamson, K. Coll, 1982, The Journal of biological chemistry.

Cyclic AMP raises cytosolic Ca2+ and promotes Ca2+ influx in a clonal pancreatic β‐cell line (HIT T‐15)

M. Prentki, B. Corkey, F. Matschinsky, 1987, FEBS letters.

Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease.

B. Corkey, R. Zoeller, J. Haller, 2011, Biochimica et biophysica acta.

Hypothesis: Induction of Autoimmunity in Type 1 Diabetes-A Lipid Focus.

B. Corkey, C. Evans-Molina, L. Kilpatrick, 2022, Diabetes.

Direct Stimulation of Islet Insulin Secretion by Glycolytic and Mitochondrial Metabolites in KCl-Depolarized Islets

J. Deeney, B. Corkey, J. Tamarit-Rodriguez, 2016, PloS one.

KCl -Permeabilized Pancreatic Islets: An Experimental Model to Explore the Messenger Role of ATP in the Mechanism of Insulin Secretion

J. Deeney, B. Corkey, J. Tamarit-Rodriguez, 2015, PloS one.

3H‐serotonin as a marker of oscillatory insulin secretion in clonal β‐cells (INS‐1)

O. Larsson, J. Deeney, B. Corkey, 2007, FEBS Letters.

Biochemical design features of the pancreatic islet cell glucose-sensory system.

M. Prentki, B. Corkey, H. Najafi, 1986, Advances in experimental medicine and biology.

Targeting Pyruvate Kinase PEPs Up Insulin Secretion and Improves Glucose Homeostasis.

B. Corkey, 2020, Cell metabolism.

Carnitine effects on coenzyme A profiles in rat liver with hypoglycin inhibition of multiple dehydrogenases.

C. Stanley, B. Y. Hsu, B. Corkey, 1997, The American journal of physiology.

Long-Chain Acyl CoA Regulation of Protein Kinase C and Fatty Acid Potentiation of Glucose-Stimulated Insulin Secretion in Clonalβ -Cells.

B. Corkey, G. Yaney, H. Korchak, 2000, Endocrinology.

Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells.

M. Prentki, J. Deeney, B. Corkey, 1992, The Journal of biological chemistry.

Metabolic partitioning of endogenous fatty acid in adipocytes.

W. Ling, B. Corkey, Wen Guo, 2003, Obesity research.

Extracellular Redox Regulation of Intracellular Reactive Oxygen Generation, Mitochondrial Function and Lipid Turnover in Cultured Human Adipocytes

T. Meshulam, N. Burritt, B. Corkey, 2016, PloS one.

Potentiation of Insulin Secretion by Phorbol Esters is Mediated by PKC-α and nPKC isoforms

J. Deeney, B. Corkey, K. Tornheim, 2002 .

Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms.

J. Deeney, B. Corkey, K. Tornheim, 2002, American Journal of Physiology. Endocrinology and Metabolism.

Mechanism of Cloned ATP-sensitive Potassium Channel Activation by Oleoyl-CoA*

F. Ashcroft, F. Gribble, B. Corkey, 1998, The Journal of Biological Chemistry.

Response to Comment on Schwartz et al. The Time Is Right for a New Classification System for Diabetes: Rationale and Implications of the β-Cell–Centric Classification Schema. Diabetes Care 2016;39:179–186

S. Grant, B. Corkey, S. Epstein, 2016, Diabetes Care.

A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating predipocytes

B. Corkey, J. Hamilton, J. Kirkland, 1998, Lipids.

Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.

B. Corkey, P. Berggren, F. Kamp, 2003, Diabetes.

Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome.

C. Stanley, D. Hale, B. Corkey, 1988, The Journal of clinical investigation.

Analysis of acyl-coenzyme A esters in biological samples.

B. Corkey, 1988, Methods in enzymology.

Integrated Mitochondrial and Microsomal Regulation of Free Ca2+ in Permeabilized Insulinoma Cells

M. Prentki, N. Ruderman, J. Deeney, 1988 .

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.

S. Yang, S. Seino, O. Larsson, 2000, Diabetes.

“En attendant Godot”: Waiting for the answer to obesity and longevity

C. Apovian, B. Corkey, 2022, Obesity.

Glucose-induced Metabolic Oscillations Parallel Those of Ca2+ and Insulin Release in Clonal Insulin-secreting Cells

M. Köhler, J. Deeney, B. Corkey, 2001, Journal of Biological Chemistry.

Negative regulation of ligand-initiated Ca2+uptake by PKC-βII in differentiated HL60 cells

B. Corkey, G. Yaney, L. Kilpatrick, 2001 .

Negative regulation of ligand-initiated Ca(2+) uptake by PKC-beta II in differentiated HL60 cells.

B. Corkey, G. Yaney, L. Kilpatrick, 2001, American journal of physiology. Cell physiology.

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells.

B. Corkey, G. Yaney, H. Korchak, 2000, Endocrinology.

[Gluco-lipotoxicity and gene expression in the pancreatic beta cell].

M. Prentki, B. Corkey, E. Roche, 1998, Journees annuelles de diabetologie de l'Hotel-Dieu.

The effect of inositol trisphosphate on Ca2+ fluxes in insulin-secreting tumor cells.

B. Corkey, J. Williamson, F. Matschinsky, 1984, The Journal of biological chemistry.

Extraction of tissue long-chain acyl-CoA esters and measurement by reverse-phase high-performance liquid chromatography.

J. Williamson, B. Corkey, G. Woldegiorgis, 1985, Analytical biochemistry.

Hyperinsulinemia: a Cause of Obesity?

B. Corkey, K. Erion, 2017, Current Obesity Reports.

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Min Wu, Junying Yuan, J. Alroy, 2008, The EMBO journal.

Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin.

B. Corkey, K. Tornheim, J. Hamilton, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Fibroblasts From Type 1 Diabetics Exhibit Enhanced Ca2+ Mobilization after TNF or Fat Exposure

B. Corkey, A. Simmons, Nicholas R Husni, 2014, PloS one.

Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells.

O. Shirihai, B. Corkey, Emma Heart, 2006, American journal of physiology. Endocrinology and metabolism.

Genetic Deficiency of Medium-Chain Acyl Coenzyme A Dehydrogenase: Studies in Cultured Skin Fibroblasts and Peripheral Mononuclear Leukocytes

C. Stanley, J. Cortner, D. Hale, 1985, Pediatric Research.

Fatty acid transport

Rebecca A. Johnson, B. Corkey, F. Kamp, 2001, Journal of Molecular Neuroscience.

A Unified Pathophysiological Construct of Diabetes and its Complications

S. Grant, B. Corkey, S. Epstein, 2017, Trends in Endocrinology & Metabolism.

Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria.

B. Corkey, J. Duszyński, J. Williamson, 1986, The Journal of biological chemistry.

Partial structure of an insulin-sensitive glycophospholipid.

B. Corkey, D. Zopf, L. Jarett, 1987, Biochemical and biophysical research communications.

Increased sensitivity of cerebrohepatorenal syndrome fibroblasts to antimycin A

B. Corkey, R. Kelley, 1983, Journal of Inherited Metabolic Disease.

Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats.

B. Corkey, J. Hamilton, J. Kirkland, 2003, Obesity research.

Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis

O. Shirihai, B. Corkey, J. Wikstrom, 2009, Diabetes.

New Scanning Electron Microscopic Method for Determination of Adipocyte Size in Humans and Mice

Lisa M Sullivan, C. Apovian, L. Sullivan, 2007, Obesity.

Synaptotagmin III Isoform Is Compartmentalized in Pancreatic -Cells and Has a Functional Role in E x o c y t o s i s

S. Seino, O. Larsson, J. Deeney, 2000 .

Temporal Profiling of the Secretome during Adipogenesis in Humans

J. Bader, A. Pandey, Jun Zhong, 2010, Journal of proteome research.

Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells

M. Prentki, B. Corkey, S. Madiraju, 2017, The Journal of Biological Chemistry.

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif

P. Århem, B. Corkey, P. Berggren, 2007, Diabetologia.

Malonyl coenzyme A and adiposity in the Dahl salt-sensitive rat: effects of pioglitazone.

N. Ruderman, B. Corkey, A. Saha, 1996, Metabolism: clinical and experimental.

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.

J. Pi, B. Corkey, M. Brownlee, 2009, Endocrinology.

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes.

M. Prentki, B. Corkey, R. A. Forse, 2001, American journal of physiology. Endocrinology and metabolism.

Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT).

B. Corkey, K. Tornheim, F. Kamp, 1994, The Journal of biological chemistry.

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.

D. Lauffenburger, C. Apovian, E. Proctor, 2019, Cell metabolism.

Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets

N. Burritt, J. Deeney, B. Corkey, 2016, PloS one.

Glucose-dependent insulin modulation of oscillatory lipolysis in perifused rat adipocytes.

B. Corkey, Lisa Getty-Kaushik, A. Richard, 2005, Obesity research.

Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).

P. Smith, B. Corkey, K. Tornheim, 2000, Diabetes.

Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)*

M. Prentki, J. Gromada, J. Deeney, 2000, The Journal of Biological Chemistry.

Oxygen Consumption Oscillates in Single Clonal Pancreatic-Cells ( HIT )

B. Corkey, K. Tornheim, Peter J. S. Smith, 2000 .

Oscillations in Oxygen Consumption by Permeabilized Clonal Pancreatic β-Cells (HIT) Incubated in an Oscillatory Glycolyzing Muscle Extract: Roles of Free Ca2+, Substrates, and the ATP/ADP Ratio

J. Deeney, B. Corkey, K. Tornheim, 1997, Diabetes.

Are the β-Cell Signaling Molecules Malonyl-CoA and Cystolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM?

M. Prentki, B. Corkey, 1996, Diabetes.

Perspectives in Diabetes Are the P-Cell Signaling Molecules Malonyl-CoA and Cytosolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM?

M. Prentki, B. Corkey, 1996 .

Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) β-cells using metformin-induced metabolic deceleration as a model

M. Prentki, B. Corkey, S. Madiraju, 2017, The Journal of Biological Chemistry.

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell

O. Shirihai, J. Deeney, B. Corkey, 2016, PloS one.

Diabetes: Have We Got It All Wrong?

B. Corkey, 2012, Diabetes Care.

Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity.

F. Hegardt, B. Corkey, J. Kirkland, 2007, American journal of physiology. Endocrinology and metabolism.

Metabolic master regulators: sharing information among multiple systems

O. Shirihai, B. Corkey, 2012, Trends in Endocrinology & Metabolism.

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.

M. Prentki, J. Deeney, B. Corkey, 1992, The Journal of biological chemistry.

altered insulin secretion caused by oleate in INS-1 cells Lipid rather than glucose metabolism is implicated in

B. Corkey, E. Roche, F. Assimacopoulos-Jeannet, 2016 .

Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells.

M. Prentki, B. Corkey, E. Roche, 1999, American journal of physiology. Endocrinology and metabolism.

Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells

M. Prentki, B. Corkey, E. Roche, 1999 .

Long chain acyl coenzyme A and signaling in neutrophils. An inhibitor of acyl coenzyme A synthetase, triacsin C, inhibits superoxide anion generation and degranulation by human neutrophils.

B. Corkey, H M Korchak, L H Kane, 1994, The Journal of biological chemistry.

Long-Chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes

B. Corkey, P. Berggren, R. Bränström, 2004, Diabetologia.

Regulation of acetyl CoA carboxylase and carnitine palmitoyl transferase-1 in rat adipocytes.

B. Corkey, Yanlin Wang-Fischer, Jianrong Han, 2005, Obesity research.

Signal transduction mechanisms in nutrient-induced insulin secretion

M. Prentki, B. Corkey, K. Tornheim, 1997, Diabetologia.

and human preadipocytes Fat depot origin affects fatty acid handling in cultured rat

M. Prentki, B. Corkey, J. McGarry, 2013 .

Acyl coenzyme a synthetase regulation: putative role in long-chain acyl coenzyme a partitioning.

B. Corkey, K. Kandror, Lisa Getty-Kaushik, 2004, Obesity research.

Free fatty acid regulation of glucose-dependent intrinsic oscillatory lipolysis in perifused isolated rat adipocytes.

B. Corkey, Lisa Getty-Kaushik, A. Richard, 2005, Diabetes.

Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus.

O. Shirihai, P. Smith, B. Corkey, 2004, American journal of physiology. Endocrinology and metabolism.

EFFECTS OF SUBLETHAL DOSES OF ENDOTOXIN AND ASPIRIN (ASA) ON RAT HEPATIC ENERGY METABOLISM: AN ANIMAL MODEL OF REYE SYNDROME

R. Polin, B. Corkey, S. Douglas, 1987, Pediatric Research.

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion.

A. Petcherski, O. Shirihai, J. Wohlschlegel, 2018, Cell metabolism.

Hyperinsulinemia: An Early Indicator of Metabolic Dysfunction

C. Apovian, Dylan D. Thomas, B. Corkey, 2019, Journal of the Endocrine Society.

The A2b Adenosine Receptor Modulates Glucose Homeostasis and Obesity

N. LeBrasseur, M. Koupenova, Dan Yang, 2012, PloS one.

Effect of artificial sweeteners on insulin secretion, ROS, and oxygen consumption in pancreatic beta cells

J. Deeney, B. Corkey, K. Tornheim, 2011 .

Acyl CoA regulation of metabolism and signal transduction.

J. Deeney, B. Corkey, 1990, Progress in clinical and biological research.

Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells.

F M Matschinsky, M. Prentki, B. Corkey, 1988, The Journal of biological chemistry.

Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells.

M. Prentki, J. Deeney, B. Corkey, 1988, The Journal of biological chemistry.

α-Ketoisovalerate Metabolism in Liver and Interactions with Other Metabolic Pathways

B. Corkey, J. Williamson, K. Coll, 1984 .

The time is now for new, lower diabetes diagnostic thresholds

B. Corkey, S. Schwartz, A. W. Rachfal, 2021, Trends in Endocrinology & Metabolism.

Glucose‐Dependent Insulinotropic Polypeptide Modulates Adipocyte Lipolysis and Reesterification

B. Corkey, Lisa Getty-Kaushik, M. Wolfe, 2006, Obesity.

Glucose-dependent insulinotropic polypeptide (GIP) promotes triglyceride synthesis in adipocytes

B. Corkey, M. Wolfe, M. Boylan, 2003 .

Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract.

F M Matschinsky, M. Prentki, N. Ruderman, 1988, The Journal of biological chemistry.

Respiration in Adipocytes is Inhibited by Reactive Oxygen Species

Yaguang Si, O. Shirihai, J. Deeney, 2010, Obesity.

What Regulates Basal Insulin Secretion and Causes Hyperinsulinemia?

J. Deeney, B. Corkey, M. Merrins, 2021, Diabetes.

Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic β-cells and HIT cells

W. F. Hopkins, B. Corkey, D. Cook, 1992, The Journal of Membrane Biology.

The L-type voltage-gated Ca2+ channel is the Ca2+ sensor protein of stimulus-secretion coupling in pancreatic beta cells.

J. Deeney, B. Corkey, D. Atlas, 2007, Biochemistry.

Building Interdisciplinary Biomedical Research Using Novel Collaboratives

K. Ravid, B. Corkey, Russell Faux, 2013, Academic medicine : journal of the Association of American Medical Colleges.

Recruitment in a Pediatric Clinical Research Trial Targeting UnderservedPopulations: Efforts and Challenges

B. Corkey, C. Lenders, K. Ireland, 2015 .

Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a HEEDS Workshop.

J. M. Stephens, L. Redman, M. Goran, 2023, The American journal of clinical nutrition.

Reactive oxygen species: role in obesity and mitochondrial energy efficiency

B. Corkey, 2023, Philosophical Transactions of the Royal Society B.

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells.

B. Corkey, G. Yaney, H. Korchak, 2000, Endocrinology.

Lipid-associated metabolic signalling networks in pancreatic beta cell function

M. Prentki, B. Corkey, S. Madiraju, 2019, Diabetologia.

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.

M. Andersen, C. Woods, Qiang Zhang, 2010, Toxicology and applied pharmacology.

Relationship betweenUnusualHepatic AcylCoenzymeA Profiles andthe Pathogenesis ofReyeSyndrome

D. Hale, B. Corkey, 1988 .

Greetings from the New Editor-in-Chief of Obesity Research

B. Corkey, 2003 .

Voices: Insulin and beyond.

F. Ashcroft, J. Holst, R. Bergman, 2021, Cell metabolism.

Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis

O. Shirihai, B. Corkey, K. Trudeau, 2017, EMBO Reports.