Jian‐He Xu

发表

Immobilization of trophic anaerobic acetogen for semi-continuous syngas fermentation

Peng Hu, Lijuan Zhang, Jiang Pan, 2020 .

Bioproduction of Glycolic Acid from Glycolonitrile with a New Bacterial Isolate of Alcaligenes sp. ECU0401

Li Zhou, Yucai He, Jian‐He Xu, 2010, Applied biochemistry and biotechnology.

Heterologous expression and characterization of a novel thermo-halotolerant endoglucanase Cel5H from Dictyoglomus thermophilum.

Jian‐He Xu, Zhimin Li, Q. Ye, 2013, Bioresource technology.

Cloning of Thermostable Cellulase Genes of Clostridium thermocellum and Their Secretive Expression in Bacillus subtilis

J. Bao, Jian‐He Xu, Jian-Ming Liu, 2012, Applied Biochemistry and Biotechnology.

Development of an engineered thermostable amine dehydrogenase for the synthesis of structurally diverse chiral amines

Jian‐He Xu, Zhilong Wang, Zhi‐Jun Zhang, 2020, Catalysis Science & Technology.

Reductive amination of ketones with ammonium catalyzed by a newly identified Brevibacterium epidermidis strain for the synthesis of (S)-chiral amines

Jian‐He Xu, Chun-Xiu Li, Lei Liu, 2018, Chinese Journal of Catalysis.

Efficient biosynthesis of rare natural product scopolamine using E. coli cells expressing a S14P/K97A mutant of hyoscyamine 6β-hydroxylase AaH6H.

Yucai He, Huilei Yu, Jian‐He Xu, 2015, Journal of biotechnology.

Engineering Isopropanol Dehydrogenase for Efficient Regeneration of Nicotinamide Cofactors

Haiyang Li, Jian‐He Xu, Zhi‐Jun Zhang, 2022, Applied and environmental microbiology.

Efficient Synthesis of 12‐Oxochenodeoxycholic Acid Using a 12α‐Hydroxysteroid Dehydrogenase fromRhodococcus ruber

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2019, Advanced Synthesis & Catalysis.

Switching Cofactor Dependence of 7β-Hydroxysteroid Dehydrogenase for Cost-Effective Production of Ursodeoxycholic Acid

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2018, ACS Catalysis.

Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolution.

Zhoutong Sun, Manfred T Reetz, Richard Lonsdale, 2015, Angewandte Chemie.

Secretory expression of cyclohexanone monooxygenase by methylotrophic yeast for efficient omeprazole sulfide bio-oxidation

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2021, Bioresources and Bioprocessing.

Iowa State University From the SelectedWorks of Zengyi Shao 2012 Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae

Huimin Zhao, Nikhil U. Nair, Hua Zhao, 2017 .

Direct Conversion of Xylan to Ethanol by Recombinant Saccharomyces cerevisiae Strains Displaying an Engineered Minihemicellulosome

Huimin Zhao, Tong Si, Fei Wen, 2012, Applied and Environmental Microbiology.

Exploitation of cold‐active cephalosporin C acylase by computer‐aided directed evolution and its potential application in low‐temperature biosynthesis of 7‐aminocephalosporanic acid

Jian‐He Xu, Tang Cunduo, Hong-Ling Shi, 2018 .

Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line.

Minbo Lan, Jian‐He Xu, Jianwen Liu, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Enzymatic transformation of vina-ginsenoside R7 to rare notoginsenoside ST-4 using a new recombinant glycoside hydrolase from Herpetosiphon aurantiacus

Zheng-Tao Wang, Jian‐He Xu, Chun-Xiu Li, 2015, Applied Microbiology and Biotechnology.

Expression and Characterization of a Novel Lipase from Aspergillus fumigatus with High Specific Activity

Jian‐He Xu, Jian Zhao, Fu-Jun Wang, 2011, Applied biochemistry and biotechnology.

Substrate channel evolution of an esterase for the synthesis of cilastatin

Huilei Yu, Jian‐He Xu, Qi Chen, 2015 .

Asymmetric Amination of Secondary Alcohols by using a Redox‐Neutral Two‐Enzyme Cascade

Jian‐He Xu, Fei-Fei Chen, G. Zheng, 2015 .

Mining methods and typical structural mechanisms of terpene cyclases

Huilei Yu, Jian‐He Xu, Zhengshuo Huang, 2021, Bioresources and Bioprocessing.

Enantioselective Bioamination of Aromatic Alkanes Using Ammonia: A Multienzymatic Cascade Approach

Huilei Yu, Jian‐He Xu, Fei-Fei Chen, 2020 .

Usage of sugar cane bagasse as an energy source for the production of lipase by Aspergillus fumigatus.

M. Rafiq, Jian‐He Xu, M. U. Dahot, 2013 .

Biocatalytic synthesis of (R)-(−)-mandelic acid from racemic mandelonitrile by cetyltrimethylammonium bromide-permeabilized cells of Alcaligenes faecalis ECU0401

Yucai He, Jian‐He Xu, Zhi‐Jun Zhang, 2010, Journal of Industrial Microbiology & Biotechnology.

Protein engineering of aldolase LbDERA for enhanced activity toward real substrates with a high-throughput screening method coupled with an aldehyde dehydrogenase.

Jiang Pan, Jian‐He Xu, X. Kong, 2017, Biochemical and biophysical research communications.

Chemoenzymatic Deracemization of Chiral Secondary Alcohols: Process Optimization for Production of (R)-1-Indanol and (R)-1-Phenylethanol

Jiang Pan, Jian‐He Xu, D. Ludwig, 2008 .

Confining Enzyme Clusters in Bacteriophage P22 Enhances Cofactor Recycling and Stereoselectivity for Chiral Alcohol Synthesis

Huilei Yu, Jian‐He Xu, Yunpeng Bai, 2021, ACS Catalysis.

Enhancing erythritol production by wheat straw biochar-incorporated solid-state fermentation of agricultural wastes using defatted Schizochytrium sp. biomass as supplementary feedstock

Jian‐He Xu, Jiaxing Xu, Yubo Yan, 2021 .

Rational selection of circular permutation sites in characteristic regions of the α/β-hydrolase fold enzyme RhEst1

Huilei Yu, Jian‐He Xu, Qi Chen, 2016 .

9. Solvent Effects in Bioreductions

Jian‐He Xu, Y. Ni, Hui-Lei Yu and, 2013 .

Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering.

Huilei Yu, Jian‐He Xu, Qi Chen, 2019, Journal of biotechnology.

Direct Access to Medium‐Chain α,ω‐Dicarboxylic Acids by Using a Baeyer–Villiger Monooxygenase of Abnormal Regioselectivity

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2018, Chembiochem : a European journal of chemical biology.

Strains Displaying an Engineered Recombinant Saccharomyces cerevisiae Direct Conversion of Xylan to Ethanol by

Tong Si, Jian‐He Xu, Jie Sun, 2012 .

Catalytic Performance of Corn Stover Hydrolysis by a New Isolate Penicillium sp. ECU0913 Producing both Cellulase and Xylanase

J. Bao, Huilei Yu, Jian‐He Xu, 2011, Applied biochemistry and biotechnology.

Efficient Transformation of Linoleic Acid into 13(S)-Hydroxy-9,11-(Z,E)-octadecadienoic Acid Using Putative Lipoxygenases from Cyanobacteria

Jian‐He Xu, Zhi‐Jun Zhang, Yu-Cong Zheng, 2020 .

Cloning and biochemical properties of a highly thermostable and enantioselective nitrilase from Alcaligenes sp. ECU0401 and its potential for (R)-(−)-mandelic acid production

Yucai He, Jian‐He Xu, Zhi‐Jun Zhang, 2011, Bioprocess and biosystems engineering.

Efficient production of (R)-(−)-mandelic acid with highly substrate/product tolerant and enantioselective nitrilase of recombinant Alcaligenes sp.

T. Imanaka, Yucai He, Jian‐He Xu, 2010 .

Integration of purification with immobilization of Candida rugosa lipase for kinetic resolution of racemic ketoprofen.

Jian‐He Xu, Hui Wu, You-Yan Liu, 2004, Journal of biotechnology.

Preparation of enantiopure (S)-ketoprofen by immobilized Candida rugosa lipase in packed bed reactor

Jian‐He Xu, Wenchang Xi, 2005 .

Highly enantioselective oxidation of racemic phenyl-1,2-ethanediol to optically pure (R)-(−)-mandelic acid by a newly isolated Brevibacterium lutescens CCZU12-1

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2013, Applied Microbiology and Biotechnology.

Asymmetric reduction of ketones by employing Rhodotorula sp. AS2.2241 and synthesis of the β-blocker (R)-nifenalol

Jian‐He Xu, Gang Zhao, Wei Yang, 2006 .

Maximum Saccharification of Cellulose Complex by an Enzyme Cocktail Supplemented with Cellulase from Newly Isolated Aspergillus fumigatus ECU0811

J. Bao, Huilei Yu, Jian‐He Xu, 2011, Applied Biochemistry and Biotechnology.

Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds

Huilei Yu, Jian‐He Xu, Fei-Fei Chen, 2020 .

Preparing β-blocker (R)-Nifenalol based on enantioconvergent synthesis of (R)-p-nitrophenylglycols in continuous packed bed reactor with epoxide hydrolase

Huilei Yu, Jian‐He Xu, Fei-Fei Chen, 2019, Tetrahedron.

Chemoenzymatic synthesis of (R)- and (S)-propranolol using an engineered epoxide hydrolase with a high turnover number

Huilei Yu, Jian‐He Xu, X. Kong, 2015 .

Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques

Jian‐He Xu, Chun-Xiu Li, Ming-min Zheng, 2015 .

Enzymatic saccharification of sugarcane bagasse by N-methylmorpholine-N-oxide-tolerant cellulase from a newly isolated Galactomyces sp. CCZU11-1.

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2013, Bioresource technology.

Biocatalytic Processes for the Synthesis of Chiral Alcohols

Jian‐He Xu, G. Zheng, Y. Ni, 2016 .

Application of High‐Throughput Screening in Biocatalysis

Jian‐He Xu, J. Tao, Jie Zhang, 2016 .

Evolution of Glucose Dehydrogenase for Cofactor Regeneration in Bioredox Processes with Denaturing Agents

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2020, Chembiochem : a European journal of chemical biology.

Optimization of Serratia marcescens lipase production for enantioselective hydrolysis of 3-phenylglycidic acid ester

Jian‐He Xu, Li Gao, Xin-Jun Li, 2004, Journal of Industrial Microbiology and Biotechnology.

Sulfonated Vermiculite-Mediated Catalysis of Reed (Phragmites communis) into Furfural for Enhancing the Biosynthesis of 2-Furoic Acid with a Dehydrogenase Biocatalyst in a One-Pot Manner

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2020 .

Facile Production of (+)-Aristolochene and (+)-Bicyclogermacrene in Escherichia coli Using Newly Discovered Sesquiterpene Synthases from Penicillium expansum.

Huilei Yu, Jian‐He Xu, Chun-Xiu Li, 2022, Journal of agricultural and food chemistry.

Accelerated directed evolution of dye-decolorizing peroxidase using a bacterial extracellular protein secretion system (BENNY)

T. S. Wong, Jian‐He Xu, K. L. Tee, 2019, Bioresources and Bioprocessing.

Synthesis of optically pure S-sulfoxide by Escherichia coli transformant cells coexpressing the P450 monooxygenase and glucose dehydrogenase genes

T. Imanaka, Huilei Yu, Jian‐He Xu, 2011, Journal of Industrial Microbiology & Biotechnology.

Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, Bioresources and Bioprocessing.

Anaesthetic effects of eugenol on preservation and transportation of yellow catfish ( Pelteobagrus fulvidraco )

Jian‐He Xu, Haodong Ding, Le Qu, 2021 .

Combinatorial evolution of phosphotriesterase toward a robust malathion degrader by hierarchical iteration mutagenesis

M. Reetz, Huilei Yu, Jian‐He Xu, 2016, Biotechnology and bioengineering.

Expanding the application scope of glycosidases using click chemistry

Jian‐He Xu, Chen Zhu, G. Lin, 2010 .

Molecular cloning and nutrient regulation analysis of long chain acyl-CoA synthetase 1 gene in grass carp, Ctenopharyngodon idella L.

Jian‐He Xu, Han-liang Cheng, Qian Pan, 2017, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Biotechnologically Relevant Enzymes and Proteins

Jian‐He Xu, Jian Zhao, X. Kong, 2022 .

Sequence analysis and heterologous expression of a new cytochrome P450 monooxygenase from Rhodococcus sp. for asymmetric sulfoxidation

Jian‐He Xu, Yi Yang, A. Li, 2009, Applied Microbiology and Biotechnology.

A new chemo-enzymatic route to chiral 2-hydroxy-4-phenylbutyrates by combining lactonase-mediated resolution with hydrogenation over Pd/C.

Jian‐He Xu, Haifeng Yin, Zhen-Sheng Wang, 2010, Chemical communications.

Increased Catalyst Productivity in α-Hydroxy Acids Resolution by Esterase Mutation and Substrate Modification

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2014 .

Marked enhancement of epoxide hydrolase production from Trichosporon loubierii ECU1040 by substrate induction and fed-batch fermentation

Jiang Pan, Jian‐He Xu, 2003 .

Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes

Huilei Yu, Jian‐He Xu, Yu-Cong Zheng, 2020 .

Monoterpene hydroxylation with an artificial self-sufficient P450 utilizing a P450SMO reductase domain for the electron transfer

Huilei Yu, Jian‐He Xu, Z. Luan, 2015 .

Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp

Jian‐He Xu, Qi Chen, X. Kong, 2014, Biotechnology and bioengineering.

A green-by-design bioprocess forl-carnosine production integrating enzymatic synthesis with membrane separation

Jiang Pan, Jian‐He Xu, You-Yan Liu, 2019, Catalysis Science & Technology.

Discovery and Engineering of a Novel Baeyer‐Villiger Monooxygenase with High Normal Regioselectivity

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2020, Chembiochem : a European journal of chemical biology.

Engineering P450LaMO stereospecificity and product selectivity for selective C–H oxidation of tetralin-like alkylbenzenes

J. Zhao, Ning Li, Huilei Yu, 2018 .

Effects of Cold Shock on Microtubule Organization and Cell Cycle in Gynogenetically Activated Eggs of Olive Flounder (Paralichthys olivaceus)

Jian‐He Xu, F. You, Pei-jun Zhang, 2006, Marine Biotechnology.

Significantly improved asymmetric oxidation of sulfide with resting cells of Rhodococcus sp. in a biphasic system

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011 .

Fingerprint lipolytic enzymes with chromogenic p-nitrophenyl esters of structurally diverse carboxylic acids

Huilei Yu, Jian‐He Xu, Chun-Xiu Li, 2011 .

Immobilization of Serratia marcescens lipase onto amino-functionalized magnetic nanoparticles for repeated use in enzymatic synthesis of Diltiazem intermediate

Jiang Pan, Huilei Yu, Jian‐He Xu, 2009 .

Coevolution of the Activity and Thermostability of an ϵ‐Keto Ester Reductase for Better Synthesis of an (R)‐α‐Lipoic Acid Precursor

Jian‐He Xu, Zhi‐Jun Zhang, Qi Chen, 2019, Chembiochem : a European journal of chemical biology.

Preparation of (R)-(−)-mandelic acid and its derivatives from racemates by enantioselective degradation with a newly isolated bacterial strain Alcaligenes sp. ECU0401

Yucai He, Jiang Pan, Jian‐He Xu, 2008, Bioprocess and biosystems engineering.

Structure-guided engineering of Pseudomonas dacunhaeL-aspartate β-decarboxylase for L-homophenylalanine synthesis.

Pengfei Hu, Jian‐He Xu, Zhi‐Jun Zhang, 2020, Chemical communications.

Biocatalysis, Cofactor Regeneration

Jian‐He Xu, Jie Zhang, 2010 .

Adzuki bean: a new resource of biocatalyst for asymmetric reduction of aromatic ketones with high stereoselectivity and substrate tolerance.

Jian‐He Xu, G. Lin, Yan Xie, 2009, Bioresource technology.

Asymmetric Reductive Amination of Structurally Diverse Ketones with Ammonia Using a Spectrum-Extended Amine Dehydrogenase

Jian‐He Xu, Dong-Hao Wang, Fei-Fei Chen, 2021, ACS Catalysis.

Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines

Jian‐He Xu, Chun-Xiu Li, Lei Liu, 2018 .

Advances in Biocatalysis: Enzymatic Reactions and Their Applications

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011 .

Isolation of lipase producer and its performance in enantioselective hydrolysis of glycidyl butyrate

Jian‐He Xu, Juntang Yu, Shishan Jia, 2003, Applied biochemistry and biotechnology.

Isolation and properties of a levo-lactonase from Fusarium proliferatum ECU2002: a robust biocatalyst for production of chiral lactones

Jiang Pan, Jian‐He Xu, Y. Xu, 2007, Applied Microbiology and Biotechnology.

Biocatalytic resolution of glycidyl aryl ethers by Trichosporon loubierii: cell/substrate ratio influences the optical purity of (R)-epoxides

Jiang Pan, Jian‐He Xu, Y. Xu, 2004, Biotechnology Letters.

Improvement the tolerance of baker's yeast to toxic substrate/product with cloud point system during the whole cell microbial transformation

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2007 .

Discovery of Two Native Baeyer-Villiger Monooxygenases for Asymmetric Synthesis of Bulky Chiral Sulfoxides

Huilei Yu, Jian‐He Xu, F. Liu, 2018, Applied and Environmental Microbiology.

Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1

Huilei Yu, Jian‐He Xu, Wenyong Lou, 2017 .

Bioreduction of methyl o-chlorobenzoylformate at 500gL−1 without external cofactors for efficient production of enantiopure clopidogrel intermediate

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2012 .

Assessing bioavailability of the solubilization of organic compound in nonionic surfactant micelles by dose–response analysis

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2010, Applied Microbiology and Biotechnology.

Immobilization of glycolate oxidase from Medicago falcata on magnetic nanoparticles for application in biosynthesis of glyoxylic acid

Jiang Pan, Huilei Yu, Jian‐He Xu, 2009 .

Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor.

Jian‐He Xu, Chun-Xiu Li, Jie Zhang, 2011, Bioresource technology.

Synthetic Biomimetic Coenzymes and Alcohol Dehydrogenases for Asymmetric Catalysis

D. Opperman, Jian‐He Xu, F. Hollmann, 2019, Catalysts.

Investigating pH and Cu (II) effects on lipase activity and enantioselectivity via kinetic and spectroscopic methods.

Jian‐He Xu, Juhua Zhong, Wei Yu, 2006, Biotechnology journal.

Burkholderia jiangsuensis sp. nov., a methyl parathion degrading bacterium, isolated from methyl parathion contaminated soil.

Jian‐He Xu, Chun-Xiu Li, Qiliang Lai, 2014, International journal of systematic and evolutionary microbiology.

Stereocomplementary Synthesis of Pharmaceutically Relevant Chiral 2-Aryl-Substituted Pyrrolidines Using Imine Reductases.

Jian‐He Xu, Fei-Fei Chen, Qi Chen, 2020, Organic letters.

Stereoselective synthesis of l-tert-leucine by a newly cloned leucine dehydrogenase from Exiguobacterium sibiricum

Jiang Pan, Jian‐He Xu, Jie Zhang, 2014 .

Immobilization of Bacillus subtilis esterase by simple cross-linking for enzymatic resolution of dl-menthyl acetate

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011 .

Direct reductive amination of ketones with amines by reductive aminases

Jian‐He Xu, Jing Zhang, Fei-Fei Chen, 2021, Green Synthesis and Catalysis.

Refolding, purification and characterization of an organic solvent-tolerant lipase from Serratia marcescens ECU1010

Jian‐He Xu, Li-qiang Fan, Su-xia Li, 2011 .

Extractive fermentation in cloud point system for lipase production by Serratia marcescens ECU1010

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2010, Applied Microbiology and Biotechnology.

Efficient Synthesis of α-D-Glucose-1-Phosphate by Maltodextrin Phosphorylase Immobilized on Amino-functionalized Magnetic Nanoparticles

Jian‐He Xu, Qing Dong, L. Ouyang, 2010 .

Confining enzyme clusters in supramolecular nanoreactors enhances cofactor-dependent cascade for chiral alcohol synthesis

Jian‐He Xu, J. Ge, Yunpeng Bai, 2020 .

Biocatalytic properties of a recombinant aldo-keto reductase with broad substrate spectrum and excellent stereoselectivity

Jian‐He Xu, Chun-Xiu Li, Jie Zhang, 2011, Applied Microbiology and Biotechnology.

An efficient bioprocess for enzymatic production of L-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2010, Journal of biotechnology.

An Eco-Friendly and Sustainable Process for Enzymatic Hydrolysis of Penicillin G in Cloud Point System

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2006, Bioprocess and biosystems engineering.

Identification, purification and characterization of β-glucosidase from apple seed as a novel catalyst for synthesis of O-glucosides

Huilei Yu, Jian‐He Xu, G. Lin, 2007 .

Enzymatic transformation of ginsenoside Rg3 to Rh2 using newly isolated Fusarium proliferatum ECU2042

Jian‐He Xu, J. Su, G. Lin, 2006 .

Asymmetric reduction of aryl ketones with a new isolate Rhodotorula sp. AS2.2241

Y. Ni, Jian‐He Xu, 2002 .

A Single Mutation Increases the Activity and Stability of Pectobacterium carotovorum Nitrile Reductase

Jian‐He Xu, Zhi‐Jun Zhang, Min Li, 2018, Chembiochem : a European journal of chemical biology.

A new thermostable β-glucosidase mined from Dictyoglomus thermophilum: properties and performance in octyl glucoside synthesis at high temperatures.

C. Hayashi, Huilei Yu, Jian‐He Xu, 2012, Bioresource technology.

A high-throughput screening strategy for nitrile-hydrolyzing enzymes based on ferric hydroxamate spectrophotometry

Li Zhou, Yucai He, Cui-Luan Ma, 2011, Applied Microbiology and Biotechnology.

Identification of an Imine Reductase for Asymmetric Reduction of Bulky Dihydroisoquinolines.

Jian‐He Xu, G. Zheng, Hao Li, 2017, Organic letters.

Construction and operation of a fibrous bed reactor with immobilized lactonase for efficient production of (R)-α-hydroxy-γ-butyrolactone

Jiang Pan, Jian‐He Xu, Dianhua Liu, 2010 .

All-Carbon-Atom Refinery of Oleic Acid into Bifunctional Chemicals Using Artificial Consortia of Escherichia coli Strains

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, ACS Sustainable Chemistry & Engineering.

Design of a self-sufficient hydride-shuttling cascade for concurrent bioproduction of 7,12-dioxolithocholate and l-tert-leucine

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2021 .

One pot simultaneous preparation of both enantiomer of β-amino alcohol and vicinal diol via cascade biocatalysis

Jian‐He Xu, Wenlong Wei, Wenchao Gao, 2018, Biotechnology Letters.

Crosslinking of enzyme coaggregate with polyethyleneimine: A simple and promising method for preparing stable biocatalyst of Serratia marcescens lipase

T. Imanaka, Jiang Pan, Jian‐He Xu, 2011 .

Multifunctional Biocatalysis: An Unusual Imine Reductase

Jian‐He Xu, Fei-Fei Chen, G. Zheng, 2022, Engineering Microbiology.

Cloning and Characterization of an Enantioselective l-Menthyl Benzoate Hydrolase from Acinetobacter sp. ECU2040

Jian‐He Xu, Jin Yin, G. Zheng, 2015, Applied Biochemistry and Biotechnology.

Isolation of a Bacillus strain producing ketone reductase with high substrate tolerance.

Jian‐He Xu, Y. Xu, Yan Xie, 2010, Bioresource technology.

Newly Identified Thermostable Esterase from Sulfobacillus acidophilus: Properties and Performance in Phthalate Ester Degradation

Jian‐He Xu, Xiangqun Fan, Yongjun Qiu, 2014, Applied and Environmental Microbiology.

Enantioselective Synthesis of Chiral Vicinal Amino Alcohols Using Amine Dehydrogenases

Jian‐He Xu, M. Thompson, N. Turner, 2019, ACS Catalysis.

High throughput solid-phase screening of bacteria with cyclic amino alcohol deamination activity for enantioselective synthesis of chiral cyclic β-amino alcohols

Jian‐He Xu, Ya-Wen Chang, Lili Gao, 2020, Biotechnology Letters.

Induction of triploidy in large yellow crocker Pseudosciaena crocea (Richardson, 1846): effects of pressure shocks and growth performance in the first rearing year

Jian‐He Xu, F. You, Pei-jun Zhang, 2008 .

Stripping of nonionic surfactants from the coacervate phase of cloud point system for lipase separation by Winsor II microemulsion extraction with the direct addition of alcohols

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2010 .

Biosynthesis of Ethyl (S)-4-Chloro-3-Hydroxybutanoate by NADH-Dependent Reductase from E. coli CCZU-Y10 Discovered by Genome Data Mining Using Mannitol as Cosubstrate

Yucai He, Jian‐He Xu, Chao Chen, 2014, Applied Biochemistry and Biotechnology.

Enantioselective synthesis of enantiopure β-amino alcohols via kinetic resolution and asymmetric reductive amination by a robust transaminase from Mycobacterium vanbaalenii.

Jian‐He Xu, Wenlong Wei, Lili Gao, 2019, Journal of biotechnology.

Efficient production of diltiazem chiral intermediate using immobilized lipase from Serratia marcescens

Jiang Pan, Jian‐He Xu, Lili Zhao, 2010 .

Asymmetric ring opening of racemic epoxides for enantioselective synthesis of (S)-β-amino alcohols by a cofactor self-sufficient cascade biocatalysis system

Jian‐He Xu, Wenlong Wei, Qiao Jia, 2019, Catalysis Science & Technology.

Properties of a novel β-glucosidase from Fusarium proliferatum ECU2042 that converts ginsenoside Rg3 into Rh2

Yucai He, Huilei Yu, Jian‐He Xu, 2009 .

Enzymatic Preparation of the Chiral (S)-Sulfoxide Drug Esomeprazole at Pilot-Scale Levels

Huilei Yu, Jian‐He Xu, Jianye Xia, 2020 .

Enhancing effect of Tween-80 on lipase performance in enantioselective hydrolysis of ketoprofen ester

Jian‐He Xu, You-Yan Liu, Yingyu Hu, 2000 .

Optimization and Scale-up of a Bioreduction Process for Preparation of Ethyl (S)-4-Chloro-3-hydroxybutanoate

Jiang Pan, Jian‐He Xu, Q. Ye, 2014 .

An ene reductase from Clavispora lusitaniae for asymmetric reduction of activated alkenes.

Huilei Yu, Jian‐He Xu, G. Lin, 2014, Enzyme and microbial technology.

Building Flexible Escherichia coli Modules for Bifunctionalizing n-Octanol: The Byproduct of Oleic Acid Biorefinery.

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, Journal of agricultural and food chemistry.

Molecular dynamics investigation of the substrate binding mechanism in carboxylesterase.

Jian‐He Xu, Xiaolin Cheng, Qi Chen, 2015, Biochemistry.

Catalytic conversion of corncob to furfuryl alcohol in tandem reaction with tin-loaded sulfonated zeolite and NADPH-dependent reductase biocatalyst.

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2020, Bioresource technology.

Biochemical properties and potential applications of an organic solvent-tolerant lipase isolated from Serratia marcescens ECU1010

Jiang Pan, Jian‐He Xu, Zhilong Wang, 2008 .

One-Pot Synthesis of Phenylglyoxylic Acid from Racemic Mandelic Acids via Cascade Biocatalysis.

Huilei Yu, Jian‐He Xu, Lun-guang Yao, 2019, Journal of agricultural and food chemistry.

Enzymes and Their Synthetic Applications: An Overview

Jian‐He Xu, J. Tao, 2009 .

Environmentally benign synthesis of natural glycosides using apple seed meal as green and robust biocatalyst.

Huilei Yu, Jian‐He Xu, G. Lin, 2008, Journal of biotechnology.

Expression and Characterization of a Novel Enantioselective Lipase from Aspergillus fumigatus

Jian‐He Xu, Jian Zhao, Fu-Jun Wang, 2012, Applied Biochemistry and Biotechnology.

Significantly Improved Equilibrium Yield of Long-Chain Alkyl Glucosides via Reverse Hydrolysis in a Water-Poor System Using Cross-Linked Almond Meal as a Cheap and Robust Biocatalyst

Huilei Yu, Jian‐He Xu, Honglai Liu, 2012 .

Neural pharmacological activity was detected among components of glycoconjugates array prepared by combinatorial biocatalysis

Huilei Yu, Jian‐He Xu, G. Lin, 2008 .

Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups.

Huilei Yu, Jian‐He Xu, J. Su, 2008, Journal of bioscience and bioengineering.

Construction and optimization of a monophasic organic–water system for enzymatic synthesis of p-nitrobenzyl β-d-glucopyranosides by reverse hydrolysis

Jian‐He Xu, G. Lin, Wen‐Ya Lu, 2005 .

Use of apple seed meal as a new source of β-glucosidase for enzymatic glucosylation of 4-substituted benzyl alcohols and tyrosol in monophasic aqueous-dioxane medium

Jian‐He Xu, G. Lin, Wen‐Ya Lu, 2004 .

Significantly Improved Expression and Biochemical Properties of Recombinant Serratia marcescens Lipase as Robust Biocatalyst for Kinetic Resolution of Chiral Ester

Jian‐He Xu, X. Mao, Yi Wang, 2010, Applied biochemistry and biotechnology.

Bioproduction of chiral mandelate by enantioselective deacylation of α-acetoxyphenylacetic acid using whole cells of newly isolated Pseudomonas sp. ECU1011

Jiang Pan, Huilei Yu, Jian‐He Xu, 2010, Applied Microbiology and Biotechnology.

A Closed Concept of Extractive Whole Cell Microbial Transformation of Benzaldehyde into l-Phenylacetylcarbinol by Saccharomyces cerevisiae in Novel Polyethylene-Glycol-Induced Cloud-Point System

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2010, Applied biochemistry and biotechnology.

Asymmetric reduction of 2-chloro-3-oxo-ester into enantiomerically high pure diltiazem precursor by a Candida ketoreductase

Jiang Pan, Jian‐He Xu, Y. Xuan, 2021 .

Asymmetric Reduction of Ketones by Employing Rhodotorula sp. AS2.2241 and Synthesis of the β-Blocker (R)-Nifenalol (XVI).

Jian‐He Xu, Gang Zhao, Wei Yang, 2006 .

Significantly improved esterase activity of Trichosporon brassicae cells for ketoprofen resolution by 2-propanol treatment

Jian‐He Xu, Hui Wu, You-Yan Liu, 2002 .

Pyrococcus furiosus-mediated reduction of conjugated carboxylic acids: Towards using syngas as reductant

Frank Hollmann, Yan Ni, I. Arends, 2014 .

A biocatalytic hydrogenation of carboxylic acids.

I. Arends, Jian‐He Xu, F. Hollmann, 2012, Chemical communications.

Biochemical properties of a new nitrile reductase cloned from Pectobacterium carotovorum

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2016 .

Highly stereoselective reduction of prochiral ketones by a bacterial reductase coupled with cofactor regeneration.

Jian‐He Xu, Chun-Xiu Li, Jie Zhang, 2011, Organic & biomolecular chemistry.

Double substituted variant of Bacillus amyloliquefaciens esterase with enhanced enantioselectivity and high activity towards 1-(3′,4′-methylenedioxyphenyl)ethyl acetate

Yun Tang, Jian‐He Xu, Yunpeng Bai, 2015, Applied Microbiology and Biotechnology.

One Pot Asymmetric Synthesis of (R)‐Phenylglycinol from Racemic Styrene Oxide via Cascade Biocatalysis

Huilei Yu, Jian‐He Xu, Y. Nie, 2019, ChemCatChem.

A Novel (R)‐Imine Reductase from Paenibacillus lactis for Asymmetric Reduction of 3 H‐Indoles

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2016 .

Efficient synthesis of chiral indolines using an imine reductase from Paenibacillus lactis

Jian‐He Xu, G. Zheng, Hao Li, 2015 .

Efficient Biocatalytic Synthesis of Chiral Chemicals.

Jian-He Xu, Zhi-Jun Zhang, Jiang Pan, 2016, Advances in biochemical engineering/biotechnology.

Reductive Amination of Biobased Levulinic Acid to Unnatural Chiral γ-Amino Acid Using an Engineered Amine Dehydrogenase

Jian‐He Xu, Aitao Li, Lei Liu, 2020 .

Overexpression of Serratia marcescens lipase in Escherichia coli for efficient bioresolution of racemic ketoprofen

Jiang Pan, Jiang Pan, Jian‐He Xu, 2007 .

Characterization of a new nitrilase from Hoeflea phototrophica DFL-43 for a two-step one-pot synthesis of (S)-β-amino acids

Jian‐He Xu, Zhi‐Jun Zhang, Rui-Feng Cai, 2018, Applied Microbiology and Biotechnology.

Asymmetric bioreduction of γ- and δ-keto acids by native carbonyl reductases from Saccharomyces cerevisiae

Jiang Pan, Jian‐He Xu, Yunpeng Bai, 2020 .

Efficient Stereoselective Synthesis of Structurally Diverse γ‐ and δ‐Lactones Using an Engineered Carbonyl Reductase

Jiang Pan, Jian‐He Xu, Yunpeng Bai, 2019, ChemCatChem.

Hydroxynitrile Lyase Isozymes from Prunus communis: Identification, Characterization and Synthetic Applications

Huilei Yu, Jian‐He Xu, R. Hong, 2017 .

Facile Access to Chiral Alcohols with Pharmaceutical Relevance Using a Ketoreductase Newly Mined from Pichia guilliermondii

Huilei Yu, Jian‐He Xu, Guo-Chao Xu, 2013 .

Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1.

Jian‐He Xu, X. Qian, G. Zheng, 2014, Chemical communications.

Biocatalytic synthesis of (-)-1-trimethylsilylethanol by asymmetric reduction of acetyltrimethylsilane with a new isolate Rhodotorula sp. AS2.2241

M. Zong, Jian‐He Xu, D. Luo, 2003 .

Enzymatic production of Cilastatin intermediate via highly enantioselective hydrolysis of methyl (±)-2,2-dimethylcyclopropane carboxylate using newly isolated Rhodococcus sp. ECU1013

Jiang Pan, Jian‐He Xu, Q. Ye, 2013, Applied Microbiology and Biotechnology.

Biocatalytic Properties of a Recombinant Fusarium proliferatum Lactonase with Significantly Enhanced Production by Optimal Expression in Escherichia coli

Jian‐He Xu, Jian Zhao, L. Ouyang, 2010, Applied biochemistry and biotechnology.

Microwave-assisted synthesis of α-hydroxy aromatic ketones from α-bromo aromatic ketones in water

Jian‐He Xu, Haiying Chen, Xiang Liu, 2011 .

Resolution of racemic sulfoxides with high productivity and enantioselectivity by a Rhodococcus sp. strain as an alternative to biooxidation of prochiral sulfides for efficient production of enantiopure sulfoxides.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011, Bioresource technology.

Isolation of Rhodococcus sp. Strain ECU0066, a New Sulfide Monooxygenase-Producing Strain for Asymmetric Sulfoxidation

Jian‐He Xu, G. Lin, A. Li, 2008, Applied and Environmental Microbiology.

Facile Synthesis of Enantiopure 4‐Substituted 2‐Hydroxy‐4‐ butyrolactones using a Robust Fusarium Lactonase

Jian‐He Xu, Haifeng Yin, Li-qiang Fan, 2009 .

Engineering Streptomyces coelicolor Carbonyl Reductase for Efficient Atorvastatin Precursor Synthesis

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2017, Applied and Environmental Microbiology.

Access to Optically Active Aryl Halohydrins Using a Substrate-Tolerant Carbonyl Reductase Discovered from Kluyveromyces thermotolerans

Huilei Yu, Jian‐He Xu, Xiaoyan Zhang, 2012 .

Efficient production of l-menthol in a two-phase system with SDS using an immobilized Bacillus subtilis esterase

Jiang Pan, Jian‐He Xu, Q. Ye, 2014, Bioresources and Bioprocessing.

Protein Engineering for Bioreduction of Carboxylic Acids.

T. S. Wong, Jian‐He Xu, K. L. Tee, 2019, Journal of biotechnology.

Enantioselective bioreductive preparation of chiral halohydrins employing two newly identified stereocomplementary reductases

Huilei Yu, Jian‐He Xu, Y. Shang, 2015 .

Enantioselectively bioreductive preparation of chiral halohydrins employing two newly identified stererocomplementary reductases

Huilei Yu, Jian‐He Xu, Y. Shang, 2014 .

Biocatalytic ketone reduction: a green and efficient access to enantiopure alcohols.

Jian‐He Xu, Y. Ni, 2012, Biotechnology advances.

Stereospecific Reduction of Methyl o‐Chlorobenzoylformate at 300 g⋅L−1 without Additional Cofactor using a Carbonyl Reductase Mined from Candida glabrata

Jian‐He Xu, Linlin Yang, Chun-Xiu Li, 2012 .

Stepwise and combinatorial optimization of enantioselectivity for the asymmetric hydrolysis of 1-(3’,4’-methylenedioxyphenyl)ethyl acetate under use of a cold-adapted Bacillus amyloliquefaciens esterase

T. Imanaka, Jian‐He Xu, G. Zheng, 2014, Biotechnology and Bioprocess Engineering.

Multi-substrate fingerprinting of esterolytic enzymes with a group of acetylated alcohols and statistic analysis of substrate spectrum

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013 .

Identification of key residues in Debaryomyces hansenii carbonyl reductase for highly productive preparation of (S)-aryl halohydrins.

Huilei Yu, Jian‐He Xu, Y. Shang, 2015, Chemical communications.

Efficient synthesis of a chiral precursor for angiotensin-converting enzyme (ACE) inhibitors in high space-time yield by a new reductase without external cofactors.

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2012, Organic letters.

Efficient Reduction of Ethyl 2-Oxo-4-phenylbutyrate at 620 g⋅L−1 by a Bacterial Reductase with Broad Substrate Spectrum

Jie Zhang, Uwe T. Bornscheuer, Yan Ni, 2011 .

Engineering 7β-Hydroxysteroid Dehydrogenase for Enhanced Ursodeoxycholic Acid Production by Multiobjective Directed Evolution.

Jian‐He Xu, Chun-Xiu Li, Hao Li, 2017, Journal of agricultural and food chemistry.

Efficient Synthesis of (R)-2-Chloro-1-(2,4-dichlorophenyl)ethanol with a Ketoreductase from Scheffersomyces stipitis CBS 6045

Huilei Yu, Jian‐He Xu, Qi Chen, 2017 .

Enantioselective production of (S)-1-phenyl-1,2-ethanediol from dicarboxyesters by recombinant Bacillus subtilis esterase

Jian‐He Xu, Zhilong Wang, Chun-Xiu Li, 2011 .

Engineered Imine Reductase for Larotrectinib Intermediate Manufacture

R. Guo, Jian‐He Xu, Fei-Fei Chen, 2022, ACS Catalysis.

Green access to chiral Vince lactam in a buffer-free aqueous system using a newly identified substrate-tolerant (−)-γ-lactamase

Jian‐He Xu, Jin Yin, G. Zheng, 2016 .

Stereocomplementary bioreduction of β-ketonitrile without ethylated byproduct.

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2013, Organic letters.

Bio-resolution of a chiral epoxide using whole cells of Bacillus megaterium ECU1001 in a biphasic system

Jian‐He Xu, P. Gong, 2005 .

Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation

Huilei Yu, Jian‐He Xu, Qin Xu, 2018, ACS Catalysis.

Discovery and utilization of biocatalysts for chiral synthesis: an overview of Chinese scientists' research and development.

Huilei Yu, Jian‐He Xu, G. Lin, 2009, Advances in biochemical engineering/biotechnology.

Cloud point of nonionic surfactant Triton X-45 in aqueous solution.

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2008, Colloids and surfaces. B, Biointerfaces.

Efficient Degradation of Malathion in the Presence of Detergents Using an Engineered Organophosphorus Hydrolase Highly Expressed by Pichia pastoris without Methanol Induction.

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2017, Journal of Agricultural and Food Chemistry.

Efficient expression of novel glutamate decarboxylases and high level production of γ-aminobutyric acid catalyzed by engineered Escherichia coli.

Jian‐He Xu, Lun-guang Yao, Yun-Chao Kan, 2020, International journal of biological macromolecules.

Discovery and Engineering of Bacterial (−)‐Isopiperitenol Dehydrogenases to Enhance (−)‐Menthol Precursor Biosynthesis

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2021, Advanced Synthesis & Catalysis.

Cross-linked enzyme-polymer conjugates with excellent stability and detergent-enhanced activity for efficient organophosphate degradation

Jian‐He Xu, J. Ge, Yunpeng Bai, 2018, Bioresources and Bioprocessing.

Improved efficiency of a novel methyl parathion hydrolase using consensus approach.

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2016, Enzyme and microbial technology.

Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala

Jiang Pan, Jian‐He Xu, Qi Chen, 2015, Bioresources and Bioprocessing.

Chemoenzymatic enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol by a newly cloned epoxide hydrolase VrEH2 from Vigna radiata

Jian‐He Xu, X. Kong, Li-qiang Fan, 2015 .

Enantioconvergent hydrolysis of styrene epoxides by newly discovered epoxide hydrolases in mung bean.

Jiang Pan, Jian‐He Xu, W. Xu, 2006, Organic letters.

Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines.

Jian‐He Xu, Xingxing Shen, N. Turner, 2023, Journal of the American Chemical Society.

Enhancing transglutaminase production of Streptomyces mobaraensis by iterative mutagenesis breeding with atmospheric and room-temperature plasma (ARTP)

Jiang Pan, Jian‐He Xu, Yunpeng Bai, 2017, Bioresources and Bioprocessing.

Highly efficient synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate and its derivatives by a robust NADH-dependent reductase from E. coli CCZU-K14.

Yucai He, Jian‐He Xu, Zhen-xing Yang, 2014, Bioresource technology.

Biosynthesis of Phenylglyoxylic Acid by LhDMDH, a Novel d-Mandelate Dehydrogenase with High Catalytic Activity.

Fei Liu, Jian‐He Xu, Lun-guang Yao, 2018, Journal of agricultural and food chemistry.

Synthesis of furoic acid from biomass via tandem pretreatment and biocatalysis

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2020 .

Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor

Jian‐He Xu, Zhen Qin, G. Zheng, 2018, ACS Catalysis.

Identification of a Robust Carbonyl Reductase for Diastereoselectively Building syn-3,5-Dihydroxy Hexanoate: a Bulky Side Chain of Atorvastatin

Jian‐He Xu, G. Zheng, You-Yan Liu, 2017 .

Identification of an ε‐Keto Ester Reductase for the Efficient Synthesis of an (R)‐α‐Lipoic Acid Precursor

Jian‐He Xu, G. Zheng, Wen-Xia Zhang, 2015 .

Efficient kinetic resolution of dl-menthol by lipase-catalyzed enantioselective esterification with acid anhydride in fed-batch reactor

Jian‐He Xu, A. Tanaka, T. Kawamoto, 1995, Applied Microbiology and Biotechnology.

Improved o-chlorobenzoylformate bioreduction by stabilizing aldo-keto reductase YtbE with additives

Huilei Yu, Jian‐He Xu, Y. Ni, 2014 .

Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates

Shuguang Yuan, She Chen, Lin Li, 2014, Proceedings of the National Academy of Sciences.

A smart library of epoxide hydrolase variants and the top hits for synthesis of (S)-β-blocker precursors.

Jian‐He Xu, X. Kong, Jiahai Zhou, 2014, Angewandte Chemie.

Asymmetric reduction of α-hydroxy aromatic ketones to chiral aryl vicinal diols using carrot enzymes system

Jian‐He Xu, Xiang Liu, Haixiang Gao, 2012 .

Enantioselective synthesis of (S)-α-cyano-3-phenoxybenzyl alcohol by lipase-catalyzed alcoholysis of racemic ester in organic medium

Jian‐He Xu, Rong Zhou, 2005 .

Efficient Production of (S)-Naproxen with (R)-Substrate Recycling Using an Overexpressed Carboxylesterase BsE-NP01

Jiang Pan, Jing Zhao, Jiang Pan, 2010, Applied biochemistry and biotechnology.

Isolation of an esterase-producing Trichosporon brassicae and its catalytic performance in kinetic resolution of ketoprofen

Jian‐He Xu, You-Yan Liu, D. Shen, 2001 .

Iterative multitarget evolution dramatically enhances the enantioselectivity and catalytic efficiency of Bacillus subtilis esterase towards bulky benzoate esters of DL-menthol

Jian‐He Xu, Jin Yin, Chun-Xiu Li, 2016 .

Improved production of (S)-ketoprofen ester hydrolase by a mutant of Trichosporon brassicae CGMCC 0574

Jian‐He Xu, Hui Wu, Qinglong Xin, 2003, Journal of Industrial Microbiology and Biotechnology.

Biocatalysis in development of green pharmaceutical processes.

Junhua Tao, Jian‐He Xu, J. Tao, 2009, Current opinion in chemical biology.

Efficient production of (R)-(−)-mandelic acid using glutaraldehyde cross-linked Escherichia coli cells expressing Alcaligenes sp. nitrilase

Jiang Pan, Huilei Yu, Jian‐He Xu, 2014, Bioprocess and Biosystems Engineering.

Highly enantioselective oxidation of racemic phenyl-1,2-ethanediol to optically pure (R)-(−)-mandelic acid by a newly isolated Brevibacterium lutescens CCZU12-1

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2013, Applied Microbiology and Biotechnology.

Efficient production of (R)-(−)-mandelic acid by isopropanol-permeabilized recombinant E. coli cells expressing Alcaligenes sp. nitrilase

T. Imanaka, Huilei Yu, Jian‐He Xu, 2015 .

Comparison of differently modified Pseudomonascepacia lipases in enantioselective preparation of a chiral alcohol for agrochemical use

U. Bornscheuer, Jian‐He Xu, Rong Zhou, 2005 .

Enzymatic Production of l‐Menthol by a High Substrate Concentration Tolerable Esterase from Newly Isolated Bacillus subtilis ECU0554

Huilei Yu, Jian‐He Xu, G. Zheng, 2009 .

Enantioselective Hydrolysis of dl-Menthyl Benzoate by Cell-Free Extract of Newly Isolated Acinetobacter sp. ECU2040

Jiang Pan, Jian‐He Xu, Jin Yin, 2013, Applied Biochemistry and Biotechnology.

Highly efficient synthesis of (R)-3-quinuclidinol in a space-time yield of 916 g L(-1) d(-1) using a new bacterial reductase ArQR.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013, Organic letters.

Asymmetric bioreduction of keto groups of 4- and 5-Oxodecanoic acids/esters with a new carbonyl reductase

Jiang Pan, Jian‐He Xu, Yunpeng Bai, 2017 .

A green-by-design system for efficient bio-oxidation of an unnatural hexapyranose into chiral lactone for building statin side-chains

Jiang Pan, Jian‐He Xu, Qi Chen, 2016 .

Enzymatic resolution of a chiral chlorohydrin precursor for (R)-α-lipoic acid synthesis via lipase catalyzed enantioselective transacylation with vinyl acetate

Jian‐He Xu, G. Zheng, Zhirong Zhu, 2014 .

New opportunities for biocatalysis: driving the synthesis of chiral chemicals.

Jian-He Xu, Gao-Wei Zheng, Jian‐He Xu, 2011, Current opinion in biotechnology.

Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.

Peter Meinhold, F. Arnold, C. Snow, 2013, Journal of biotechnology.

A mini-review of Chinese contributions to Journal of Molecular Catalysis B: Enzymatic

Jian‐He Xu, Jian-He Xu, 2002 .

Significant enhancement of (R)-mandelic acid production by relieving substrate inhibition of recombinant nitrilase in toluene-water biphasic system.

Jiang Pan, Zhi-Jun Zhang, Yucai He, 2011, Journal of biotechnology.

Directed evolution of a D-mandelate dehydrogenase toward D-o-chloromandelic acid and insight into the molecular basis for its catalytic performance

Jian‐He Xu, Tang Cunduo, Hong-Ling Shi, 2020 .

Efficient production of (R)-o-chloromandelic acid by deracemization of o-chloromandelonitrile with a new nitrilase mined from Labrenzia aggregata

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2012, Applied Microbiology and Biotechnology.

Engineering Bacillus subtilis Isoleucine Dioxygenase for Efficient Synthesis of (2S,3R,4S)-4-Hydroxyisoleucine.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2020, Journal of agricultural and food chemistry.

An Unusual (R)-Selective Epoxide Hydrolase with High Activity for Facile Preparation of Enantiopure Glycidyl Ethers

Yun Tang, J. Zhao, Jiang Pan, 2011 .

Biocatalytic preparation of (S)-phenyl glycidyl ether using newly isolated Bacillus megaterium ECU1001

Jian‐He Xu, Q. Ye, Yan Tang, 2001 .

Altering the Substrate Specificity of Reductase CgKR1 from Candida glabrata by Protein Engineering for Bioreduction of Aromatic α‐Keto Esters

Huilei Yu, Jian‐He Xu, Lei Huang, 2014 .

Deracemization of aryl secondary alcohols via enantioselective oxidation and stereoselective reduction with tandem whole-cell biocatalysts

Jian‐He Xu, Yun-long Li, Y. Xu, 2010 .

Significantly improved thermostability of a reductase CgKR1 from Candida glabrata with a key mutation at Asp 138 for enhancing bioreduction of aromatic α-keto esters.

Huilei Yu, Jian‐He Xu, Lei Huang, 2015, Journal of biotechnology.

Engineering of an oleate hydratase for efficient C10-Functionalization of oleic acid.

Jiang Pan, Jian‐He Xu, Qi Chen, 2020, Biochemical and biophysical research communications.

Enzymatic synthesis of 10-oxostearic acid in high space-time yield via cascade reaction of a new oleate hydratase and an alcohol dehydrogenase.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2019, Journal of biotechnology.

Enantioselective Esterification of Racemic Acid Catalyzed by Lipase in a Mixed Solvent System a

Jian‐He Xu, Xue‐Shu Xu, Jun-min Liu, 1998 .

Continuous Production of Ursodeoxycholic Acid by Using Two Cascade Reactors with Co‐immobilized Enzymes

Jian‐He Xu, Chun-Xiu Li, Hao Li, 2018, Chembiochem : a European journal of chemical biology.

High-yield production of enantiopure 2-hydroxy-2-(2′-chlorophenyl) acetic acid by long-term operation of a continuous packed bed reactor

Jiang Pan, Huilei Yu, Jian‐He Xu, 2016 .

Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution.

Zhoutong Sun, Aitao Li, Manfred T Reetz, 2016, Angewandte Chemie.

A Baeyer-Villiger monooxygenase from Cupriavidus basilensis catalyzes asymmetric synthesis of (R)-lansoprazole and other pharmaco-sulfoxides

Chen Zhao, Huilei Yu, Jian‐He Xu, 2021, Applied Microbiology and Biotechnology.

Improving Pseudomonas sp. esterase performance by engineering approaches for kinetic resolution of 2-acetoxyphenylacetic acids

Jiang Pan, Huilei Yu, Jian‐He Xu, 2011 .

Efficient resolution of a chiral alcohol (RS)-HMPC by enzymatic transesterification with vinyl acetate using surfactant-modified lipase

Jian‐He Xu, Hui Wu, S. Tsang, 2004 .

Catalytic resolution of (RS)-HMPC acetate by immobilized cells of Acinetobacter sp. CGMCC 0789 in a medium with organic cosolvent

Jiang Pan, Jian‐He Xu, Ya Chen, 2004 .

Whole cell microbial transformation in cloud point system

Jian‐He Xu, Zhilong Wang, Jian-He Xu, 2008, Journal of Industrial Microbiology & Biotechnology.

Assembly of a three-dimensional array of glycoconjugates by combinatorial biocatalysis in nonaqueous media.

Hui-Lei Yu, Guo-Qiang Lin, Huilei Yu, 2008, Journal of combinatorial chemistry.

Effects of partial replacement of fishmeal with blood meal and dried porcine soluble on the growth, body composition and intestinal morphology of Cyprinus carpio

Shucun Sun, Jian‐He Xu, Q. Gao, 2020 .

Unusually Broad Substrate Profile of Self‐Sufficient Cytochrome P450 Monooxygenase CYP116B4 from Labrenzia aggregata

Huilei Yu, Jian‐He Xu, Peng Ouyang, 2014, Chembiochem : a European journal of chemical biology.

Enhancing the Catalytic Performance of a CYP116B Monooxygenase by Transdomain Combination Mutagenesis

J. Zhao, Huilei Yu, Jian‐He Xu, 2018, ChemCatChem.

Rapid probing of the reactivity of P450 monooxygenases from the CYP116B subfamily using a substrate-based method

Huilei Yu, Jian‐He Xu, Jiangmeng Ren, 2016 .

Target-oriented discovery of a new esterase-producing strain Enterobacter sp. ECU1107 for whole cell-catalyzed production of (2S,3R)-3-phenylglycidate as a chiral synthon of Taxol

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013, Applied Microbiology and Biotechnology.

Improved expression of recombinant cytochrome P450 monooxygenase in Escherichia coli for asymmetric oxidation of sulfides

Jian‐He Xu, A. Li, Jiandong Zhang, 2010, Bioprocess and biosystems engineering.

Cloning and Characterization of a Novel Esterase from Rhodococcus sp. for Highly Enantioselective Synthesis of a Chiral Cilastatin Precursor

Jiang Pan, Jian‐He Xu, Sunghoon Park, 2014, Applied and Environmental Microbiology.

Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis

Jiang Pan, Jian‐He Xu, Zhi‐Jun Zhang, 2015 .

Production, Characterization, and Application of an Organic Solvent-Tolerant Lipase Present in Active Inclusion Bodies

Jian‐He Xu, Su-xia Li, H. Pang, 2012, Applied Biochemistry and Biotechnology.

Essential Role of Gly33 in a Novel Organic Solvent-Tolerant Lipase from Serratia marcescens ECU1010 as Determined by Site-Directed Mutagenesis

Q. Ma, Jian‐He Xu, Su-xia Li, 2014, Applied Biochemistry and Biotechnology.

NADH-dependent lactate dehydrogenase from Alcaligenes eutrophus H16 reduces 2-oxoadipate to 2-hydroxyadipate

Sun-Gu Lee, Bharat Madan, E. Seol, 2014, Biotechnology and Bioprocess Engineering.

Induction of diploid gynogenesis in turbot Scophthalmus maximus with left-eyed flounder Paralichthys olivaceus sperm

Jian‐He Xu, F. You, Pei-jun Zhang, 2008, Aquaculture International.

Effect of Ultraviolet Irradiation on Sperm of the Left-eyed Flounder, Paralichthys olivaceus

Jian‐He Xu, F. You, Pei-jun Zhang, 2008 .

Effects of dietary lipid levels on growth performance, feed utilization and fatty acid composition of juvenile Japanese seabass (Lateolabrax japonicus) reared in seawater

Jian‐He Xu, B. Yan, Ming Zhu, 2011, Aquaculture International.

Effects of ultra-violet irradiation on sperm motility and diploid gynogenesis induction in large yellow croaker (Pseudosciaena crocea) undergoing cold shock

Jian‐He Xu, F. You, Pei-jun Zhang, 2007, Aquaculture International.

Separation of enantiopure m-substituted 1-phenylethanols in high space-time yield using Bacillus subtilis esterase

Jian‐He Xu, Zhi‐Jun Zhang, G. Zheng, 2013 .

Effects of dietary lipid levels on the growth, digestive enzyme, feed utilization and fatty acid composition of Japanese sea bass (Lateolabrax japonicus L.) reared in freshwater.

Jian‐He Xu, B. Yan, Yajuan Teng, 2010 .

Catalytic performance of a highly enantioselective (R)-ester hydrolase from a new isolate Acinetobacter sp. CGMCC 0789

Jian‐He Xu, Jing Qian, 2004 .

High level and enantioselective production of L-phenylglycine from racemic mandelic acid by engineered Escherichia coli using response surface methodology.

Jian‐He Xu, Lun-guang Yao, Yun-Chao Kan, 2020, Enzyme and microbial technology.

Preparation of immunomagnetic nanoparticles and their application in the separation of mouse CD34+ hematopoietic stem cells

Wei Chen, Xin Liang, Ke Xu, 2009 .

Performance of a New Thermostable Mannanase in Breaking Guar-Based Fracturing Fluids at High Temperatures with Little Premature Degradation

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2014, Applied Biochemistry and Biotechnology.

Random and combinatorial mutagenesis for improved total production of secretory target protein in Escherichia coli

T. S. Wong, Jian‐He Xu, K. L. Tee, 2021, Scientific Reports.

Enzymatic hydrolysis of penicillin G to 6-aminopenicillanic acid in cloud point system with discrete countercurrent experiment

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2007 .

ASYMMETRIC REDUCTION OF AROMATIC KETONES BY THE BAKER'S YEAST IN ORGANIC SOLVENT SYSTEMS

Jian‐He Xu, Xiang Liu, Tong Zhu, 2001 .

Thermostable Bacterial Endoglucanases Mined from Swiss-Prot Database

Jian‐He Xu, Q. Ye, Zhilong Wang, 2011, Applied biochemistry and biotechnology.

Clean enzymatic production of ursodeoxycholic acid enabled by a newly identified NADH-dependent 7β-hydroxysteroid dehydrogenase

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2023, Molecular Catalysis.

Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition.

Jian‐He Xu, Qi Chen, Jie Zhang, 2014, Biochemical and biophysical research communications.

Molecular characterization and tissue-specific expression of the acetyl-CoA carboxylase α gene from Grass carp, Ctenopharyngodon idella.

Jian‐He Xu, Han-liang Cheng, Nanjing Ji, 2011, Gene.

Enzymatic surface modification of acrylic fiber

Jian‐He Xu, Ningkang Wang, Yin Xu, 2004 .

Improved production of Pseudomonas sp. ECU1011 acetyl esterase by medium design and fed-batch fermentation

Jiang Pan, Huilei Yu, Jian‐He Xu, 2012, Bioprocess and Biosystems Engineering.

Novel polyethylene glycol induced cloud point system for extraction and back-extraction of organic compounds

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2009 .

A downstream process with microemulsion extraction for microbial transformation in cloud point system

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2008 .

In situ extraction of polar product of whole cell microbial transformation with polyethylene glycol‐induced cloud point system

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2008, Biotechnology progress.

Investigation of extractive microbial transformation in nonionic surfactant micelle aqueous solution using response surface methodology

Jian‐He Xu, Zhilong Wang, Yingying Xue, 2009, Applied Microbiology and Biotechnology.

Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases.

Zhi-Jun Zhang, Romas J. Kazlauskas, A. Dean, 2016, Journal of the American Chemical Society.

A thermostable and organic-solvent tolerant esterase from Pseudomonas putida ECU1011: catalytic properties and performance in kinetic resolution of α-hydroxy acids.

Jiang Pan, Huilei Yu, Jian‐He Xu, 2013, Bioresource technology.

Microfluidic reactor with immobilized enzyme-from construction to applications: A review

Jian‐He Xu, N. Zhu, Yunpeng Bai, 2021 .

Chemoenzymatic construction of chiral alkenyl acetylenic alcohol, a key building block to access diastereoisomers of polyacetylenes

Jian‐He Xu, R. Hong, Wenhua Li, 2015, Bioresources and Bioprocessing.

Isolation and Biochemical Characterization of Two Novel Metagenome-Derived Esterases

Jian‐He Xu, L. Ouyang, Jia-ying Liu, 2012, Applied Biochemistry and Biotechnology.

A 3D-QSAR assisted activity prediction strategy for expanding substrate spectra of an aldehyde ketone reductase

Qi Chen, Hui-Lei Yu, Huilei Yu, 2018, Molecular Catalysis.

Department of Bioengineering

Jian‐He Xu, Jian‐He Xu, 2010 .

Dramatically Improved Performance of an Esterase for Cilastatin Synthesis by Cap Domain Engineering

Huilei Yu, Jian‐He Xu, Qi Chen, 2016 .

Evolution of a Catalytic Mechanism.

A. Dean, Markus Lunzer, Jian‐He Xu, 2016, Molecular biology and evolution.

Identification of a new thermostable and alkali-tolerant α-carbonic anhydrase from Lactobacillus delbrueckii as a biocatalyst for CO2 biomineralization

Jian‐He Xu, Chun-Xiu Li, Yongqiu Qiu, 2015, Bioresources and Bioprocessing.

Engineering of Cyclohexanone Monooxygenase for the Enantioselective Synthesis of (S)-Omeprazole

Huilei Yu, Jian‐He Xu, Qiang Zhao, 2019, ACS Sustainable Chemistry & Engineering.

Enhanced limonene production by optimizing the expression of limonene biosynthesis and MEP pathway genes in E. coli

Huilei Yu, Jian‐He Xu, Chun-Xiu Li, 2014, Bioresources and Bioprocessing.

Draft Genome Sequence of Burkholderia sp. Strain MP-1, a Methyl Parathion (MP)-Degrading Bacterium from MP-Contaminated Soil

Jian‐He Xu, Chun-Xiu Li, Qiliang Lai, 2014, Genome Announcements.

Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7-Oxo-lithocholic Acid

Jian‐He Xu, Yunpeng Bai, G. Zheng, 2021, ACS Sustainable Chemistry & Engineering.

Efficient biosynthesis of uridine diphosphate glucose from maltodextrin by multiple enzymes immobilized on magnetic nanoparticles.

Huilei Yu, Jian‐He Xu, Qing Dong, 2010, Carbohydrate research.

Significantly enhanced production of recombinant nitrilase by optimization of culture conditions and glycerol feeding

Jiang Pan, Jian‐He Xu, Zhi‐Jun Zhang, 2011, Applied Microbiology and Biotechnology.

Biocatalytic Synthesis of (R)-(-)-mandelic Acid from Racemic Mandelonitrile by a Newly Isolated nitrilase-producer Alcaligenes sp. ECU0401

Yucai He, Jiang Pan, Jian‐He Xu, 2007 .

Minihemicellulosome Strains Displaying an Engineered Recombinant Saccharomyces cerevisiae Direct Conversion of Xylan to Ethanol

Huimin Zhao, Tong Si, Jian‐He Xu, 2012 .

Thermodynamic equilibrium control of the enzymatic hydrolysis of penicillin G in a cloud point system without pH control

Jian‐He Xu, Zhilong Wang, Hanshi Qi, 2006 .

Engineered Glycosidase for Significantly Improved Production of Naturally Rare Vina-Ginsenoside R7.

Jian‐He Xu, X. Kong, Shujuan Zhao, 2023, Journal of agricultural and food chemistry.

Heterologous overexpression of Vigna radiata epoxide hydrolase in Escherichia coli and its catalytic performance in enantioconvergent hydrolysis of p-nitrostyrene oxide into (R)-p-nitrophenyl glycol

Jian‐He Xu, Jian Zhao, X. Kong, 2013, Applied Microbiology and Biotechnology.

Efficient production of ethyl (R)-2-hydroxy-4-phenylbutyrate using a cost-effective reductase expressed in Pichia pastoris

Jiang Pan, Jian‐He Xu, X. Ju, 2014 .

[Computational analysis of structure-activity relationship of industrial enzymes].

Qi Chen, Chunxiu Li, Gaowei Zheng, 2019, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Protein engineering of thioether monooxygenase to improve its thermostability for enzymatic synthesis of chiral sulfoxide

Jiang Pan, Huilei Yu, Jian‐He Xu, 2021 .

Halogenation/Dehalogenation/Heteroatom Oxidation

J. Damborský, R. Chaloupkova, Jiang Pan, 2012 .

Modified ferric hydroxamate spectrophotometry for assaying glycolic acid from the hydrolysis of glycolonitrile by Rhodococcus sp. CCZU10-1

Yucai He, Cui-Luan Ma, Jian‐He Xu, 2011 .

Fractal kinetic analysis of polymers/nonionic surfactants to eliminate lignin inhibition in enzymatic saccharification of cellulose.

H. Feng, Jian‐He Xu, Zhilong Wang, 2011, Bioresource technology.

Bioamination of alkane with ammonium by an artificially designed multienzyme cascade.

Chao Yang, Huilei Yu, Jian‐He Xu, 2018, Metabolic engineering.

Characterization of a new nitrilase from Hoeflea phototrophica DFL-43 for a two-step one-pot synthesis of (S)-β-amino acids

Jian‐He Xu, Zhi‐Jun Zhang, Rui Cai, 2018, Applied Microbiology and Biotechnology.

Efficient production of (R)-o-chloromandelic acid by deracemization of o-chloromandelonitrile with a new nitrilase mined from Labrenzia aggregata

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2012, Applied Microbiology and Biotechnology.

Efficient Synthesis of Methyl 3-Acetoxypropionate by a Newly Identified Baeyer-Villiger Monooxygenase

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2019, Applied and Environmental Microbiology.

An extraordinary stringent and sensitive light-switchable gene expression system for bacterial cells

Q. Ouyang, Jian‐He Xu, Xianjun Chen, 2016, Cell Research.

Asymmetric reduction of aromatic ketones with a novel crude enzyme system from Adzuki beans

Jian‐He Xu, G. Lin, Yan Xie, 2008 .

Significant Improvement of Serratia marcescens Lipase Fermentation, by Optimizing Medium, Induction, and Oxygen Supply

Jiang Pan, Jian‐He Xu, Z. Long, 2007, Applied biochemistry and biotechnology.

A novel D-mandelate dehydrogenase used in three-enzyme cascade reaction for highly efficient synthesis of non-natural chiral amino acids.

Jian‐He Xu, Changli Fan, Yunpeng Bai, 2015, Journal of biotechnology.

Remove the Obstacle to (-)-Menthol Biosynthesis by Building a Microbial Cell Factory of (+)-cis-Isopulegone from (-)-Limonene.

Jian‐He Xu, Chun-Xiu Li, Yu‐Cong Zheng, 2021, ChemSusChem.

A biocatalytic synthesis of diosgenyl-β-d-glucopyranoside by the use of four recombinant enzymes in one pot

Huilei Yu, Jian‐He Xu, Qing Dong, 2010 .

A new high‐energy density hydrogen carrier—carbohydrate—might be better than methanol

Jian‐He Xu, J. Zhong, Y. Percival Zhang, 2013 .

Identification two key residues at the intersection of domains of a thioether monooxygenase for improving its sulfoxidation performance

Huilei Yu, Jian‐He Xu, Zhi‐Jun Zhang, 2020, Biotechnology and bioengineering.

Facile Biosynthesis of Taxadiene by a Newly Constructed Escherichia coli Strain Fusing Enzymes Taxadiene Synthase and Geranylgeranyl Pyrophosphate Synthase

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, Process Biochemistry.

Rational design of a carboxylic esterase RhEst1 based on computational analysis of substrate binding.

Huilei Yu, Jian‐He Xu, Xiaolin Cheng, 2015, Journal of molecular graphics & modelling.

Rational Engineering of Formate Dehydrogenase Substrate/Cofactor Affinity for Better Performance in NADPH Regeneration

Jiang Pan, Jian‐He Xu, Qi Chen, 2020, Applied Biochemistry and Biotechnology.

Effective biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate by supplementation of l-glutamine, d-xylose and β-cyclodextrin in n-butyl acetate-water media.

Yucai He, Jian‐He Xu, Yun Lu, 2015, Journal of biotechnology.

Improving Enzymatic Production of Ginsenoside Rh2 from Rg3 by using Nonionic Surfactant

Jian‐He Xu, Zhilong Wang, J. Su, 2010, Applied biochemistry and biotechnology.

An Ammonium-Formate-Driven Trienzymatic Cascade for ω-Transaminase-Catalysed (R)-Selective Amination.

Jian‐He Xu, Jianping Wu, Zhi‐Jun Zhang, 2019, The Journal of organic chemistry.

Regiospecific C–H amination of (−)-limonene into (−)-perillamine by multi-enzymatic cascade reactions

Jiang Pan, Jian‐He Xu, Chun-Xiu Li, 2022, Bioresources and Bioprocessing.

A High‐Throughput Screening Method for the Directed Evolution of Hydroxynitrile Lyase towards Cyanohydrin Synthesis

Huilei Yu, Jian‐He Xu, Qiao Jia, 2020, Chembiochem : a European journal of chemical biology.

Directed evolution for improved total secretory protein production in Escherichia coli

T. S. Wong, Jian‐He Xu, K. L. Tee, 2020 .

Efficient synthesis of an ε-hydroxy ester in a space–time yield of 1580 g L−1 d−1 by a newly identified reductase RhCR

Jian‐He Xu, G. Zheng, Y. Ni, 2014 .

Heterogeneous Expression of Epoxide Hydrolase Genes from Populus Tomentosa and Application of the Enzyme for Biocatalytic Resolution of Chiral Epoxides: Heterogeneous Expression of Epoxide Hydrolase Genes from Populus Tomentosa and Application of the Enzyme for Biocatalytic Resolution of Chiral Epox

Jiang Pan, Jian‐He Xu, X. Ju, 2013 .

Discovery and utilization of biocatalysts for chiral synthesis: an overview of Chinese scientists' research and development.

Huilei Yu, Jian‐He Xu, G. Lin, 2009, Advances in biochemical engineering/biotechnology.

Engineering a norcoclaurine synthase for one-step synthesis of (S)-1-aryl-tetrahydroisoquinolines

Jian‐He Xu, Fei-Fei Chen, Qi Chen, 2023, Bioresources and Bioprocessing.

Sustainable and Robust Closed-Loop Enzymatic Platform for Continuous/Semi-continuous Synthesis of Ursodeoxycholic Acid

Jian‐He Xu, Chun-Xiu Li, G. Zheng, 2022, ACS Sustainable Chemistry & Engineering.

Direct Access to Medium‐Chain α,ω‐Dicarboxylic Acids by Using a Baeyer–Villiger Monooxygenase of Abnormal Regioselectivity

Jian‐He Xu, Yunpeng Bai, Chun-Xiu Li, 2018, Chembiochem : a European journal of chemical biology.

Structural investigation of the enantioselectivity and thermostability mechanisms of esterase RhEst1.

Qi Chen, Xiaolin Cheng, Hui-Lei Yu, 2018, Journal of molecular graphics & modelling.

Highly enantioselective hydrolysis of phenyl-1,2-ethanediol cyclic carbonates by newly isolated Bacillus sp. ECU0015

Lei Chang, Jiang Pan, Jian‐He Xu, 2010 .

Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition.

Jian‐He Xu, Qi Chen, Jie Zhang, 2014, Biochemical and Biophysical Research Communications - BBRC.

A PRACTICAL ENZYMATIC METHOD FOR PREPARATION OF (S)-KETOPROFEN WITH A CRUDE CANDIDA RUGOSA LIPASE

Jian‐He Xu, Hui Wu, You-Yan Liu, 2001 .

Department of Bioengineering

Jian‐He Xu, 2010 .

Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolution.

M. Reetz, Jian‐He Xu, R. Lonsdale, 2015, Angewandte Chemie.

Strain improvement of Serratia marcescens ECU1010 and medium cost reduction for economic production of lipase

Jian‐He Xu, Lili Zhao, Xiaoxuan Chen, 2010 .

Biotechnologically Relevant Enzymes and Proteins

Yun Tang, Jian‐He Xu, Yunpeng Bai, 2022 .