S. McKenna

发表

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods.

Trushar R. Patel, Astha, J. Bujnicki, 2017, Methods.

Solution conformation of adenovirus virus associated RNA-I and its interaction with PKR.

Trushar R. Patel, J. Bujnicki, M. Boniecki, 2014, Journal of structural biology.

The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation

Amit Koul, S. McKenna, F. Lin, 2017, Molecular Cancer.

Uev1A amino terminus stimulates poly-ubiquitin chain assembly and is required for NF-κB activation.

W. Xiao, S. McKenna, Zhaojia Wu, 2020, Cellular signalling.

Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU

Trushar R. Patel, J. Stetefeld, S. McKenna, 2015, PloS one.

Insights into the RNA quadruplex binding specificity of DDX21.

S. McKenna, E. McRae, David E Davidson, 2018, Biochimica et biophysica acta. General subjects.

Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge

Trushar R. Patel, J. Stetefeld, S. McKenna, 2018, Nucleic acids research.

Energetics and specificity of interactions within Ub.Uev.Ubc13 human ubiquitin conjugation complexes.

W. Xiao, L. Spyracopoulos, S. McKenna, 2003, Biochemistry.

Regulation of the interferon-inducible 2'-5'-oligoadenylate synthetases by adenovirus VA(I) RNA.

L. Donald, S. McKenna, Edis Dzananovic, 2012, Journal of molecular biology.

Binding and photodynamic action of the cationic zinc phthalocyanines with different types of DNA toward understanding of their cancer therapy activity.

S. McKenna, V. Nemykin, E. McRae, 2019, Journal of inorganic biochemistry.

The Dynamic Landscape of the Full-Length HIV-1 Transactivator of Transcription.

S. McKenna, Edis Dzananovic, J. O'Neil, 2016, Biochemistry.

Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR

S. McKenna, E. P. Booy, P. Ezzati, 2018, Nucleic acids research.

Purification and properties of the ubiquitin-conjugating enzymes Cdc34 and Ubc13.Mms2.

C. Ptak, X. Varelas, S. McKenna, 2005, Methods in enzymology.

Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthetase 2 (OAS2).

Amit Koul, S. McKenna, Soumya Deo, 2020, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes

R. Andersen, F. van Petegem, A. Mui, 2020, bioRxiv.

Adjuvants Based on Hybrid Antibiotics Overcome Resistance in Pseudomonas aeruginosa and Enhance Fluoroquinolone Efficacy.

S. McKenna, Soumya Deo, G. Zhanel, 2016, Angewandte Chemie.

Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2

Trushar R. Patel, J. Stetefeld, Amit Koul, 2020, Biophysical journal.

Activation of 2′ 5′-Oligoadenylate Synthetase by Stem Loops at the 5′-End of the West Nile Virus Genome

Trushar R. Patel, S. Harding, S. McKenna, 2014, PloS one.

RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3′-Tail of the Long Non-coding RNA BC200 (BCYRN1)*

J. Stetefeld, S. McKenna, Edis Dzananovic, 2015, The Journal of Biological Chemistry.

BindingofG-quadruplexestotheN-terminalRecognitionDomain oftheRNAHelicaseAssociatedwithAU-richElement(RHAU) *

Trushar R. Patel, S. Harding, S. McKenna, 2013 .

Abscisic Acid Analogues That Act as Universal or Selective Antagonists of Phytohormone Receptors.

S. McKenna, S. Abrams, M. Loewen, 2016, Biochemistry.

Dynamic light scattering: a practical guide and applications in biomedical sciences

Trushar R. Patel, J. Stetefeld, S. McKenna, 2016, Biophysical Reviews.

Purification and characterization of transcribed RNAs using gel filtration chromatography

Colin Echeverría Aitken, R. Marshall, J. Puglisi, 2007, Nature Protocols.

The anti-hepatitis C agent nitazoxanide induces phosphorylation of eukaryotic initiation factor 2alpha via protein kinase activated by double-stranded RNA activation.

J. Puglisi, M. Elazar, Michael Liu, 2009, Gastroenterology.

Alu RNA and their roles in human disease states

S. McKenna, Daniel Gussakovsky, 2021, RNA biology.

The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells

S. McKenna, Taegi Choi, Daniel Gussakovsky, 2020, The Journal of biological chemistry.

The non-coding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumour cells.

S. McKenna, Taegi Choi, Daniel Gussakovsky, 2020, The Journal of biological chemistry.

An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21

S. McKenna, R. Fahlman, Ramanaguru S Piragasam, 2019, bioRxiv.

Human DDX21 binds and unwinds RNA guanine quadruplexes

J. Stetefeld, S. McKenna, P. Ezzati, 2017, Nucleic acids research.

The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1

J. Stetefeld, S. McKenna, S. Novakowski, 2013, Nucleic acids research.

Viral proteins targeting host protein kinase R to evade an innate immune response: a mini review

Trushar R. Patel, S. McKenna, Edis Dzananovic, 2018, Biotechnology & genetic engineering reviews.

Nanoscale Assembly of High-Mobility Group AT-Hook 2 Protein with DNA Replication Fork.

Trushar R. Patel, J. Stetefeld, S. McKenna, 2017, Biophysical journal.

Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination.

W. Xiao, S. McKenna, M. Ellison, 2002, Gene.

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

Honglin Zhou, W. Xiao, V. Dixit, 2005, The Journal of cell biology.

Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition

Janusz M Bujnicki, Grzegorz Chojnowski, Trushar R Patel, 2017, PloS one.

Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR.

Trushar R. Patel, J. Stetefeld, S. McKenna, 2013, RNA.

Binding of G-quadruplexes to the N-terminal Recognition Domain of the RNA Helicase Associated with AU-rich Element (RHAU)*

Trushar R Patel, Trushar R. Patel, S. Harding, 2013, The Journal of Biological Chemistry.

The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary

J. Stetefeld, S. McKenna, S. Novakowski, 2012, Nucleic acids research.

Molecular Framework for the Activation of RNA-dependent Protein Kinase*♦

J. Puglisi, Corey W. Liu, G. Wagner, 2007, Journal of Biological Chemistry.

Monitoring Enzymatic RNA G-Quadruplex Unwinding Activities by Nuclease Sensitivity and Reverse Transcription Stop Assays.

S. McKenna, Steven J Dupas, N. Atefi, 2021, Methods in molecular biology.

PKR: A NMR perspective

Colin Echeverría Aitken, J. Puglisi, Corey W. Liu, 2007 .

An NMR-based Model of the Ubiquitin-bound Human Ubiquitin Conjugation Complex Mms2·Ubc13

Michael J. Ellison, Wei Xiao, W. Xiao, 2003, The Journal of Biological Chemistry.

Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-oligoadenylate synthetase family.

Trushar R. Patel, J. Bujnicki, G. Chojnowski, 2015, Journal of structural biology.

Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR.

Colin Echeverría Aitken, J. Puglisi, D. Lindhout, 2007, Journal of molecular biology.

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

Michael J. Ellison, J. N. Mark Glover, Wei Xiao, 2001, Nature Structural Biology.

Native RNA purification by gel filtration chromatography.

S. McKenna, H. Meng, E. Booy, 2012, Methods in molecular biology.

Rapid purification of RNAs using fast performance liquid chromatography (FPLC).

Joseph D Puglisi, J. Puglisi, S. McKenna, 2006, RNA.

On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids

S. McKenna, Evan P Booy, Sean A McKenna, 2017, Journal of nucleic acids.

The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation

Amit Koul, S. McKenna, F. Lin, 2017, Molecular Cancer.

Biophysical and biochemical investigations of dsRNA-activated kinase PKR.

J. Puglisi, D. Lindhout, S. McKenna, 2007, Methods in enzymology.

Fluorophore ligand binding and complex stabilization of the RNA Mango and RNA Spinach aptamers

S. McKenna, P. Unrau, Sunny C. Y. Jeng, 2016, RNA.

Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.

C. Ptak, S. McKenna, M. Ellison, 2001, Structure.

2D Saturation Transfer Difference NMR for Determination of Protein Binding Sites on RNA Guanine Quadruplexes.

S. McKenna, David E Davidson, Ewan K. S. McRae, 2020, Methods in molecular biology.

Uncoupling of RNA binding and PKR kinase activation by viral inhibitor RNAs.

J. Puglisi, Corey W. Liu, S. McKenna, 2006, Journal of molecular biology.

Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle*

Trushar R. Patel, J. Bacik, Mazdak Khajehpour, 2013, The Journal of Biological Chemistry.

Microfluidic Devices for Studying the Effect of Netrin‐1 on Neutrophil and Breast Cancer Cell Migration

J. Stetefeld, S. McKenna, F. Lin, 2018 .

Molecular Insights into PKR Activation by Viral Double-Stranded RNA

Colin Echeverría Aitken, J. Puglisi, D. Lindhout, 2007 .

Protein Structural Analysis

Mazdak Khajehpour, S. McKenna, B. Mark, 2011 .

Dynamic light scattering: a practical guide and applications in biomedical sciences

Trushar R. Patel, J. Stetefeld, S. McKenna, 2016, Biophysical Reviews.

Dynamic light scattering: a practical guide and applications in biomedical sciences.

Trushar R. Patel, S. McKenna, J. Stetefeld, 2016, Biophysical reviews.

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods.

Trushar R. Patel, Astha, J. Bujnicki, 2017, Methods.

Impact of G-quadruplex loop conformation in the PITX1 mRNA on protein and small molecule interaction.

J. Stetefeld, S. McKenna, Edis Dzananovic, 2017, Biochemical and biophysical research communications.

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13

W. Xiao, J. Glover, R. Edwards, 2001, Nature Structural Biology.

Nuclear SRP9/SRP14 heterodimer transcriptionally regulates 7SL and BC200 RNA expression

S. McKenna, Daniel Gussakovsky, E. Booy, 2023, RNA.