G. Grüber

发表

Coarse-Grained Molecular Modeling of the Solution Structure Ensemble of Dengue Virus Nonstructural Protein 5 with Small-Angle X-ray Scattering Intensity.

Lanyuan Lu, Guanhua Zhu, W. Saw, 2017, The journal of physical chemistry. B.

A WNK kinase binds and phosphorylates V‐ATPase subunit C

Gerhard Grüber, K. Schumacher, G. Grüber, 2006, FEBS letters.

Structural Insights into Substrate Binding by PvFKBP35, a Peptidylprolyl cis-trans Isomerase from the Human Malarial Parasite Plasmodium vivax

J. Lescar, G. Grüber, Joon Shin, 2013, Eukaryotic Cell.

Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase

G. Grüber, T. Dick, Subhashri Kundu, 2016, Antimicrobial Agents and Chemotherapy.

Conformational Properties of Secondary Amino Acids: Replacement of Pipecolic Acid by N‐Methyl‐L‐alanine in Efrapeptin C

G. Grüber, Z. Majer, M. Hollósi, 2013, Chemistry & biodiversity.

Structural features of the g subunit of the Escherichia coli F 1 ATPase revealed by a 4.4-Å resolution map obtained by x-ray crystallography

B. Matthews, A. Hausrath, G. Grüber, 1999 .

Active site CP‐loop dynamics modulate substrate binding, catalysis, oligomerization, stability, over‐oxidation and recycling of 2‐Cys Peroxiredoxins

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2018, Free radical biology & medicine.

Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C assembling.

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2019, Free radical biology & medicine.

Crystal Structure of the NS3 Protease-Helicase from Dengue Virus

Ting Xu, S. Vasudevan, J. Lescar, 2007, Journal of Virology.

Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin.

Tsutomu Matsui, Thomas M Weiss, Gerhard Grüber, 2017, Acta crystallographica. Section D, Structural biology.

Crystal structure of the NS3 protease-helicase from dengue virus

S. Vasudevan, J. Lescar, G. Grüber, 2008 .

The C-terminal 50 Amino Acid Residues of Dengue NS3 Protein Are Important for NS3-NS5 Interaction and Viral Replication*

Moon Y. F. Tay, J. Forwood, S. Vasudevan, 2014, The Journal of Biological Chemistry.

Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein’s omega-site and the GPI lipid anchor’s phosphoethanolamine

Birgit Eisenhaber, Frank Eisenhaber, Gerhard Grüber, 2014, Cell cycle.

Evidence for Major Structural Changes in the Manduca sexta Midgut V1 ATPase Due to Redox Modulation

D. Svergun, G. Grüber, M. Koch, 2000, The Journal of Biological Chemistry.

Resolution of the V1 ATPase from Manduca sexta into Subcomplexes and Visualization of an ATPase-active A3B3EG Complex by Electron Microscopy*

Teresa Ruiz, Michael Radermacher, M. Radermacher, 2003, The Journal of Biological Chemistry.

Investigation of Temperature Dependency on the Propulsion of Disk-like Nanoswimmers

J. Miao, G. Grüber, Liangxing Hu, 2017 .

Temperature effects on disk-like gold-nickel-platinum nanoswimmer’s propulsion fuelled by hydrogen peroxide

J. Miao, G. Grüber, Liangxing Hu, 2017 .

Conformational dynamics of the rotary subunit F in the A3B3DF complex of Methanosarcina mazei Gö1 A‐ATP synthase monitored by single‐molecule FRET

G. Grüber, M. Börsch, Hendrik Sielaff, 2017, FEBS letters.

Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

W. Saw, G. Grüber, Joon Shin, 2019, Scientific Reports.

The NMR solution structure of Mycobacterium tuberculosis F‐ATP synthase subunit ε provides new insight into energy coupling inside the rotary engine

G. Grüber, T. Dick, Subhashri Kundu, 2018, The FEBS journal.

Variations of Subunit ε of the Mycobacterium tuberculosis F1Fo ATP Synthase and a Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207

M. Roessle, G. Grüber, S. Basak, 2012, Antimicrobial Agents and Chemotherapy.

Structure-function relationships of A-, F- and V-ATPases.

V. Müller, G. Grüber, H. Wieczorek, 2001, The Journal of experimental biology.

STRUCTURE – FUNCTION RELATIONSHIPS OF A-, FAND V-ATPases

V. Müller, G. Grüber, H. Wieczorek, 2022 .

Trapping of conformations of the Escherichia coli F1 ATPase by disulfide bond formation

G. Grüber, R. Aggeler, R. Capaldi, 1998, FEBS letters.

The Trapping of Different Conformations of the Escherichia coli F1 ATPase by Disulfide Bond Formation

G. Grüber, R. Capaldi, Roderick A. Capaldi, 1996, The Journal of Biological Chemistry.

Solution structure of subunit F (Vma7p) of the eukaryotic V(1)V(O) ATPase from Saccharomyces cerevisiae derived from SAXS and NMR spectroscopy.

M. Roessle, G. Grüber, S. Gayen, 2011, Biochimica et biophysica acta.

Three-dimensional structure and subunit topology of the V(1) ATPase from Manduca sexta midgut.

M. Radermacher, G. Grüber, H. Wieczorek, 2000, Biochemistry.

The structure of the V(1)-ATPase determined by three-dimensional electron microscopy of single particles.

M. Radermacher, G. Grüber, H. Wieczorek, 2001, Journal of structural biology.

Structural features and nucleotide-binding capability of the C subunit are integral to the regulation of the eukaryotic V1Vo ATPases.

G. Grüber, 2005, Biochemical Society transactions.

Pyrazinamide triggers degradation of its target aspartate decarboxylase

T. Akopian, E. Rubin, G. Grüber, 2019, Nature Communications.

Structural Determination of Functional Units of the Nucleotide Binding Domain (NBD94) of the Reticulocyte Binding Protein Py235 of Plasmodium yoelii

G. Grüber, P. Preiser, J. Jeyakanthan, 2010, PloS one.

Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1

G. Grüber, T. Dick, P. Ragunathan, 2022, Antimicrobial Agents and Chemotherapy.

Introduction: Novel insights into TB research and drug discovery.

G. Grüber, 2020, Progress in biophysics and molecular biology.

Discovery of a novel Mycobacterial F-ATP synthase inhibitor and its potency in combination with diarylquinolines.

W. Saw, G. Grüber, Joon Shin, 2020, Angewandte Chemie.

Discovery of a Novel Mycobacterial F‐ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines

W. Saw, G. Grüber, Joon Shin, 2020, Angewandte Chemie.

TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug’s Uncoupler Activity

G. Grüber, T. Dick, C. Cooper, 2019, Antimicrobial Agents and Chemotherapy.

Unique structural and mechanistic properties of mycobacterial F-ATP synthases: Implications for drug design.

W. Saw, G. Grüber, Joon Shin, 2019, Progress in biophysics and molecular biology.

Structural insight into the glycosylphosphatidylinositol transamidase subunits PIG-K and PIG-S from yeast.

F. Eisenhaber, S. Maurer-Stroh, B. Eisenhaber, 2011, Journal of structural biology.

Solution structure and conformational changes of the Streptomyces chitin-binding protein (CHB1).

D. Svergun, G. Grüber, M. Koch, 2000, Biochemistry.

Structural Characterization of the Erythrocyte Binding Domain of the Reticulocyte Binding Protein Homologue Family of Plasmodium yoelii

G. Grüber, P. Preiser, Ardina Grüber, 2011, Infection and Immunity.

Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa

S. Rice, J. Lescar, G. Grüber, 2017, Journal of bacteriology.

Crystal and NMR Structures Give Insights into the Role and Dynamics of Subunit F of the Eukaryotic V-ATPase from Saccharomyces cerevisiae*

G. Grüber, S. Basak, A. M. Balakrishna, 2013, The Journal of Biological Chemistry.

Pharmacological and Molecular Mechanisms Behind the Sterilizing Activity of Pyrazinamide.

G. Grüber, T. Dick, V. Dartois, 2019, Trends in pharmacological sciences.

Low resolution solution structure of an enzymatic active AhpC10:AhpF2 ensemble of the Escherichia coli Alkyl hydroperoxide Reductase.

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2016, Journal of structural biology.

Hydrogen-peroxide-fuelled platinum–nickel–SU-8 microrocket with steerable propulsion using an eccentric nanoengine

J. Miao, G. Grüber, Liangxing Hu, 2016 .

Identification and characterization of a unique, zinc-containing transport ATPase essential for natural transformation in Thermus thermophilus HB27

V. Müller, G. Grüber, B. Averhoff, 2011, Extremophiles.

Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol.

G. Grüber, A. M. Balakrishna, Arvind Kumar, 2016, Free radical biology & medicine.

Low-resolution structure of the soluble domain GPAA1 (yGPAA170–247) of the glycosylphosphatidylinositol transamidase subunit GPAA1 from Saccharomyces cerevisiae

F. Eisenhaber, B. Eisenhaber, W. Saw, 2013, Bioscience reports.

Binding properties of the anti-TB drugs bedaquiline and TBAJ-876 to a mycobacterial F-ATP synthase

P. Bond, A. Krah, G. Grüber, 2022, Current Research in Structural Biology.

Crystallization and preliminary X-ray crystallographic analysis of subunit F (F(1-94)), an essential coupling subunit of the eukaryotic V(1)V(O)-ATPase from Saccharomyces cerevisiae.

G. Grüber, S. Basak, A. M. Balakrishna, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification and crystallization of the entire recombinant subunit E of the energy producer A(1)A(o) ATP synthase.

G. Grüber, A. M. Balakrishna, C. Hunke, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils

S. Sze, S. Adav, G. Grüber, 2019, Scientific Reports.

Essential role of the flexible linker on the conformational equilibrium of bacterial peroxiredoxin reductase for effective regeneration of peroxiredoxin

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2017, The Journal of Biological Chemistry.

Atomic solution structure of Mycobacterium abscessus F‐ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor

G. Grüber, A. Harikishore, T. Dick, 2022, The FEBS journal.

Domain features of the peripheral stalk subunit H of the methanogenic A1AO ATP synthase and the NMR solution structure of H(1-47).

G. Grüber, S. Gayen, G. Biuković, 2009, Biophysical journal.

Solution Structure, Determined by Nuclear Magnetic Resonance, of the b30-82 Domain of Subunit b of Escherichia coli F 1 F o ATP Synthase (cid:1)

G. Grüber, S. Gayen, G. Biuković, 2009 .

Structure of Arabidopsis CESA3 catalytic domain with its substrate UDP-glucose provides insight into the mechanism of cellulose synthesis

S. Persson, W. Saw, G. Grüber, 2021, Proceedings of the National Academy of Sciences.

Pyrazinoic Acid Inhibits Mycobacterial Coenzyme A Biosynthesis by Binding to Aspartate Decarboxylase PanD.

G. Grüber, T. Dick, V. Dartois, 2017, ACS infectious diseases.

Power Stroke Angular Velocity Profiles of Archaeal A-ATP Synthase Versus Thermophilic and Mesophilic F-ATP Synthase Molecular Motors*

G. Grüber, G. Biuković, W. Frasch, 2016, The Journal of Biological Chemistry.

The effect of NBD-Cl in nucleotide-binding of the major subunit α and B of the motor proteins F1FO ATP synthase and A1AO ATP synthase

M. Roessle, G. Grüber, C. Hunke, 2010, Journal of bioenergetics and biomembranes.

Cloning, purification, and nucleotide-binding traits of the catalytic subunit A of the V1VO ATPase from Aedes albopictus.

Wei-June Chen, G. Grüber, H. Schäfer, 2007, Protein expression and purification.

Interaction between subunit C (Vma5p) of the yeast vacuolar ATPase and the stalk of the C-depleted V(1) ATPase from Manduca sexta midgut.

G. Grüber, Y. Chaban, E. Boekema, 2005, Biochimica et biophysica acta.

Dimer formation of subunit G of the yeast V‐ATPase

S. Bailer, G. Grüber, M. Koch, 2003, FEBS letters.

8-N(3)-3'-biotinyl-ATP, a novel monofunctional reagent: differences in the F(1)- and V(1)-ATPases by means of the ATP analogue.

Y. Kagawa, G. Grüber, H. Wieczorek, 2001, Biochemical and biophysical research communications.

Structural architecture and interplay of the nucleotide- and erythrocyte binding domain of the reticulocyte binding protein Py235 from Plasmodium yoelii.

G. Grüber, P. Preiser, Ardina Grüber, 2012, International journal for parasitology.

Mutational Analysis of Mycobacterial F-ATP Synthase Subunit δ Leads to a Potent δ Enzyme Inhibitor.

V. Müller, Dennis Litty, W. Saw, 2022, ACS chemical biology.

Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor.

W. Saw, G. Grüber, Joon Shin, 2022, ACS infectious diseases.

Protein-protein interactions within the ensemble, eukaryotic V-ATPase, and its concerted interactions with cellular machineries.

G. Grüber, A. M. Balakrishna, M. Manimekalai, 2015, Progress in biophysics and molecular biology.

The boxing glove shape of subunit d of the yeast V-ATPase in solution and the importance of disulfide formation for folding of this protein

M. Roessle, G. Grüber, Y. R. Thaker, 2007, Journal of bioenergetics and biomembranes.

Defined subcomplexes of the A1 ATPase from the archaeon Methanosarcina mazei Gö1: biochemical properties and redox regulation

V. Müller, G. Grüber, R. Schmid, 2003, FEBS letters.

The Beauty of a Visualized Peroxo-diiron(III) Intermediate.

G. Grüber, 2015, Structure.

Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors

H. Noji, Dennis Litty, W. Saw, 2022, Antimicrobial agents and chemotherapy.

The stimulating role of subunit F in ATPase activity inside the A1-complex of the Methanosarcina mazei Gö1 A1AO ATP synthase.

G. Grüber, S. Bhushan, Hendrik Sielaff, 2016, Biochimica et biophysica acta.

The molecular motor F-ATP synthase is targeted by the tumoricidal protein HAMLET.

G. Grüber, C. Svanborg, Hendrik Sielaff, 2015, Journal of molecular biology.

Solution structure of subunit a, a104-363, of the Saccharomyces cerevisiae V-ATPase and the importance of its C-terminus in structure formation

M. Roessle, W. Saw, G. Grüber, 2012, Journal of Bioenergetics and Biomembranes.

Purification characterization of the inhibitory subunit (δ) of the ATP‐synthase from Micrococcus luteus

G. Grüber, W. Junge, T. Nawroth, 1994 .

Evidence for major structural changes in subunit C of the vacuolar ATPase due to nucleotide binding

Michael Börsch, Gerhard Grüber, K. Schumacher, 2005, FEBS letters.

Mycobacterium tuberculosis PanD Structure-Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor.

G. Grüber, Joon Shin, S. Rishikesan, 2021, ACS chemical biology.

Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase

G. Grüber, A. Harikishore, R. Bates, 2020, Molecular Diversity.

Identification of the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3.

W. Saw, G. Grüber, Ardina Grüber, 2016, Acta crystallographica. Section D, Structural biology.

The transition-like state and Pi entrance into the catalytic a subunit of the biological engine A-ATP synthase.

G. Grüber, J. Jeyakanthan, Anil Kumar, 2011, Journal of molecular biology.

Structural and Functional Features of theEscherichia coliF1-ATPase

G. Grüber, 2000 .

Substrate‐induced structural alterations of Mycobacterial mycothione reductase and critical residues involved

G. Grüber, Malathy Sony Subramanian Manimekalai, Arvind Kumar, 2018, FEBS letters.

Crystal structure of the archaeal A1Ao ATP synthase subunit B from Methanosarcina mazei Gö1: Implications of nucleotide-binding differences in the major A1Ao subunits A and B.

Michael Börsch, Monika G Düser, Ingmar B. Schäfer, 2006, Journal of molecular biology.

The Plasma Membrane H+-V-ATPase from Tobacco Hornworm Midgut

G. Grüber, H. Merzendorfer, H. Wieczorek, 1999, Journal of bioenergetics and biomembranes.

Purification and crystallization of yeast glycosylphosphatidylinositol transamidase subunit PIG-S (PIG-S(71-467)).

F. Eisenhaber, B. Eisenhaber, S. Adhikari, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase

G. Grüber, N. Sewald, A. M. Balakrishna, 2009, Proteins.

Features and functional importance of key residues of the Mycobacterium tuberculosis cytochrome bd oxidase.

G. Grüber, Malathy Sony Subramanian Manimekalai, Kevin Pethe, 2020, ACS infectious diseases.

Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis

D. Schnappinger, A. Steyn, M. Berney, 2020, EMBO molecular medicine.

Anti-tuberculosis activity of the anti-malaria cytochrome bcc oxidase inhibitor SCR0911.

G. Grüber, T. Dick, G. Cook, 2020, ACS infectious diseases.

Targeting the menaquinol binding loop of mycobacterial cytochrome bd oxidase

G. Grüber, A. Harikishore, R. Bates, 2020, Molecular Diversity.

TBAJ-876 Retains Bedaquiline’s Activity against Subunits c and ε of Mycobacterium tuberculosis F-ATP Synthase

Christopher B. Cooper, G. Grüber, Joon Shin, 2019, Antimicrobial Agents and Chemotherapy.

Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

M. Berney, G. Grüber, S. Alonso, 2017, Proceedings of the National Academy of Sciences.

ATP synthases from archaea: the beauty of a molecular motor.

V. Müller, G. Grüber, F. Mayer, 2014, Biochimica et biophysica acta.

ATP synthases: structure, function and evolution of unique energy converters

V. Müller, G. Grüber, V. Müller, 2003, Cellular and Molecular Life Sciences CMLS.

Conserved glycine residues in the P-loop of ATP synthases form a doorframe for nucleotide entrance.

G. Grüber, Anil Kumar, M. Manimekalai, 2011, Journal of molecular biology.

The Stem Region of Premembrane Protein Plays an Important Role in the Virus Surface Protein Rearrangement during Dengue Maturation*

Markus R Wenk, Gerhard Grüber, Pei-Yong Shi, 2012, The Journal of Biological Chemistry.

Introduction: A Close Look at the Vacuolar ATPase

G. Grüber, 2003, Journal of bioenergetics and biomembranes.

Title The uniqueness of subunit of mycobacterial F-ATPsynthases : An evolutionary variant for niche adaptation

G. Grüber, T. Dick, T. Wohland, 2019 .

3D reconstruction and flexibility of the hybrid engine Acetobacterium woodii F-ATP synthase.

P. Bond, V. Müller, G. Grüber, 2020, Biochemical and biophysical research communications.

Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents.

G. Grüber, A. Harikishore, T. Dick, 2022, Bioorganic & medicinal chemistry.

Structural and functional analysis of the coupling subunit F in solution and topological arrangement of the stalk domains of the methanogenic A1AO ATP synthase

Ingmar B. Schäfer, V. Müller, G. Grüber, 2006, Journal of bioenergetics and biomembranes.

Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer

M. Tanner, G. Grüber, M. Witschel, 2018, Nature Communications.

Residues of helix ɑ2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C

G. Grüber, N. Kamariah, Shi Min Sherilyn Chong, 2020, FEBS letters.

Atomic structure and enzymatic insights into the vancomycin‐resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C

G. Grüber, S. Bhushan, A. M. Balakrishna, 2018, Free radical biology & medicine.

Novel insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F.

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2017, Biochimica et biophysica acta. General subjects.

AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C

W. Saw, G. Grüber, Joon Shin, 2017, Scientific Reports.

A systematic assessment of mycobacterial F1‐ATPase subunit ε’s role in latent ATPase hydrolysis

S. Sze, W. Saw, G. Grüber, 2020, The FEBS journal.

Molecular mechanism of the Escherichia coli AhpC in the function of a chaperone under heat-shock conditions

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2018, Scientific Reports.

Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2016, Scientific Reports.

Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity

Gerhard Grüber, G. Grüber, C. Svanborg, 2012, PloS one.

Bioenergetics of Archaea: ATP Synthesis under Harsh Environmental Conditions

V. Müller, G. Grüber, V. Müller, 2006, Journal of Molecular Microbiology and Biotechnology.

Structure and Subunit Arrangement of the A-type ATP Synthase Complex from the Archaeon Methanococcus jannaschii Visualized by Electron Microscopy*

Wilko Keegstra, V. Müller, G. Grüber, 2004, Journal of Biological Chemistry.

Molecular architecture of Manduca sexta midgut V1 ATPase visualized by electron microscopy

M. Radermacher, G. Grüber, H. Wieczorek, 1999, FEBS letters.

ATP synthesis and hydrolysis of the ATP-synthase from Micrococcus luteus regulated by an inhibitor subunit and membrane energization.

G. Grüber, T. Nawroth, J. Godovac-Zimmermann, 1994, Biochimica et biophysica acta.

Structural Characterization of an ATPase Active F1-/V1 -ATPase (α3β3EG) Hybrid Complex*

G. Grüber, Y. Chaban, G. Oostergetel, 2004, Journal of Biological Chemistry.

Expression, purification, and characterization of subunit E, an essential subunit of the vacuolar ATPase.

S. Bailer, G. Grüber, U. Coskun, 2002, Biochemical and biophysical research communications.

Structural changes in the γ and ε subunits of theEscherichia coli F1F0-type ATPase during energy coupling

G. Grüber, R. Aggeler, R. Capaldi, 1996 .

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.

J. Forwood, S. Vasudevan, W. Saw, 2019, ACS infectious diseases.

Relevance of the conserved histidine and asparagine residues in the phosphate-binding loop of the nucleotide binding subunit B of A₁A₀ ATP synthases.

G. Grüber, C. Hunke, L. Sundararaman, 2012, Journal of structural biology.

Engineered tryptophan in the adenine-binding pocket of catalytic subunit A of A-ATP synthase demonstrates the importance of aromatic residues in adenine binding, forming a tool for steady-state and time-resolved fluorescence spectroscopy.

G. Grüber, M. Manimekalai, V. S. Tadwal, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Binding of subunit E into the A-B interface of the A(1)A(O) ATP synthase.

V. Müller, G. Grüber, Martin Antosch, 2011, Biochimica et biophysica acta.

The critical roles of residues P235 and F236 of subunit A of the motor protein A-ATP synthase in P-loop formation and nucleotide binding.

G. Grüber, J. Jeyakanthan, A. M. Balakrishna, 2010, Journal of molecular biology.

Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution.

G. Grüber, J. Jeyakanthan, A. M. Balakrishna, 2010, Journal of molecular biology.

Structural analysis of the stalk subunit Vma5p of the yeast V‐ATPase in solution

D. Svergun, S. Bailer, G. Grüber, 2004, FEBS letters.

Structural elements of the C-terminal domain of subunit E (E133-222) from the Saccharomyces cerevisiae V1VO ATPase determined by solution NMR spectroscopy

G. Grüber, S. Rishikesan, 2011, Journal of bioenergetics and biomembranes.

NMR solution structure of subunit E (fragment E1–69) of the Saccharomyces cerevisiae V1VO ATPase

G. Grüber, S. Rishikesan, Y. R. Thaker, 2011, Journal of bioenergetics and biomembranes.

The NMR solution structure of subunit G (G(61)(-)(101)) of the eukaryotic V1VO ATPase from Saccharomyces cerevisiae.

G. Grüber, S. Rishikesan, M. Manimekalai, 2010, Biochimica et biophysica acta.

N‐terminal domain of the V‐ATPase a2‐subunit displays integral membrane protein properties

G. Grüber, V. Marshansky, M. Merkulova, 2010, Protein science : a publication of the Protein Society.

Specific motifs of the V-ATPase a2-subunit isoform interact with catalytic and regulatory domains of ARNO.

G. Grüber, Y. R. Thaker, V. Marshansky, 2010, Biochimica et biophysica acta.

Assembly of subunit d (Vma6p) and G (Vma10p) and the NMR solution structure of subunit G (G(1-59)) of the Saccharomyces cerevisiae V(1)V(O) ATPase.

G. Grüber, S. Gayen, S. Rishikesan, 2009, Biochimica et biophysica acta.

New insights into structure‐function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0)

G. Grüber, V. Marshansky, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

Spectroscopical identification of residues of subunit G of the yeast V-ATPase in its connection with subunit E

G. Grüber, S. Gayen, S. Rishikesan, 2008, Molecular membrane biology.

Ligand-Dependent Structural Changes in the V1 ATPase from Manduca sexta

G. Grüber, M. Koch, Ü. Coskun, 2004, Journal of bioenergetics and biomembranes.

Crystallographic and solution structure of the N‐terminal domain of the Rel protein from Mycobacterium tuberculosis

G. Grüber, J. Jeyakanthan, A. M. Balakrishna, 2017, FEBS letters.

Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress.

F. Eisenhaber, V. Kostyuchenko, T. Ng, 2014, Biochimica et biophysica acta.

Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli.

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2014, Acta crystallographica. Section D, Biological crystallography.

Eukaryotic V-ATPase: novel structural findings and functional insights.

J. Rubinstein, G. Grüber, V. Marshansky, 2014, Biochimica et biophysica acta.

Association of the eukaryotic V1VO ATPase subunits a with d and d with A

G. Grüber, Y. R. Thaker, S. Shochat, 2009, FEBS letters.

Quaternary structure of V1 and F1 ATPase: significance of structural homologies and diversities.

D. Svergun, V. Volkov, G. Grüber, 1998, Biochemistry.

The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation

G. Grüber, T. Dick, T. Wohland, 2017, The Journal of Biological Chemistry.

Crystallographic structure of the turbine c-ring from spinach chloroplast F-ATP synthase.

G. Grüber, N. Dencher, H. Seelert, 2014, Bioscience reports.

Solution structure of subunit γ (γ1-204) of the Mycobacterium tuberculosis F-ATP synthase and the unique loop of γ165-178, representing a novel TB drug target

G. Grüber, Srinivasa P. S. Rao, G. Biuković, 2013, Journal of Bioenergetics and Biomembranes.

Structural features of the gamma subunit of the Escherichia coli F(1) ATPase revealed by a 4.4-A resolution map obtained by x-ray crystallography.

B. Matthews, A. Hausrath, G. Grüber, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A model of the quaternary structure of the Escherichia coli F1 ATPase from X-ray solution scattering and evidence for structural changes in the delta subunit during ATP hydrolysis.

D I Svergun, D. Svergun, G. Grüber, 1998, Biophysical journal.

An improved purification of ECF1 and ECF1F0 by using a cytochrome bo‐deficient strain of Escherichia coli facilitates crystallization of these complexes

A. Hausrath, G. Grüber, R. Capaldi, 1997, FEBS letters.

Self-coacervation of modular squid beak proteins - a comparative study.

G. Grüber, A. Miserez, S. Salentinig, 2017, Soft matter.

Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport

G. Grüber, Q. T. Nguyen, H. Yoon, 2015, Scientific Reports.

Crystallographic and solution studies of NAD(+)- and NADH-bound alkylhydroperoxide reductase subunit F (AhpF) from Escherichia coli provide insight into sequential enzymatic steps.

F. Eisenhaber, B. Eisenhaber, G. Grüber, 2015, Biochimica et biophysica acta.

Structure and flexibility of non-structural proteins 3 and -5 of Dengue- and Zika viruses in solution.

W. Saw, G. Grüber, Ardina Grüber, 2019, Progress in biophysics and molecular biology.

The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2*

J. Rubinstein, D. Ausiello, G. Grüber, 2013, The Journal of Biological Chemistry.

Eukaryotic V-ATPase and Its Super-complexes: From Structure and Function to Disease and Drug Targeting

G. Grüber, M. Futai, V. Marshansky, 2016 .

The structural features of Acetobacterium woodii F‐ATP synthase reveal the importance of the unique subunit γ‐loop in Na+ translocation and ATP synthesis

V. Müller, G. Grüber, S. Bhushan, 2019, The FEBS journal.

Structural features of Zika virus non‐structural proteins 3 and ‐5 and its individual domains in solution as well as insights into NS3 inhibition

W. Saw, G. Grüber, Ankita Pan, 2017, Antiviral research.

A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(0) ATP synthase.

G. Grüber, A. M. Balakrishna, Anil Kumar, 2009, Journal of structural biology.

Phosphorylation regulates auto-inhibition of kinesin KIF3A

C. Verma, Dilraj Lama, W. Saw, 2018 .

A New Method for Determining Structure Ensemble: Application to a RNA Binding Di-Domain Protein.

Daiwen Yang, Jing-Song Fan, G. Grüber, 2016, Biophysical journal.

Analyzing conformational changes in single FRET-labeled A1 parts of archaeal A1AO-ATP synthase

Dhirendra Singh, Michael Börsch, Hendrik Sielaff, 2018, BiOS.

Atomic structure of the regulatory TGS domain of Rel protein from Mycobacterium tuberculosis and its interaction with deacylated tRNA

G. Grüber, Ardina Grüber, Shin Joon, 2021, FEBS letters.

Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein

G. Grüber, Joon Shin, M. Chen, 2020, The FEBS journal.

Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design.

D. Ausiello, G. Grüber, Y. R. Thaker, 2019, Current topics in membranes.

Structural insight and flexible features of NS5 proteins from all four serotypes of Dengue virus in solution.

T. Matsui, T. Weiss, S. Vasudevan, 2015, Acta crystallographica. Section D, Biological crystallography.

Structure and function of Mycobacterium-specific components of F-ATP synthase subunits α and ε.

G. Grüber, Joon Shin, S. Bhushan, 2018, Journal of structural biology.

Structural and mechanistic insights into Mycothiol Disulphide Reductase and the Mycoredoxin-1-alkylhydroperoxide reductase E assembly of Mycobacterium tuberculosis.

G. Grüber, Joon Shin, Arvind Kumar, 2017, Biochimica et biophysica acta. General subjects.

Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering

G. Grüber, S. Gayen, J. Jeyakanthan, 2010, Journal of bioenergetics and biomembranes.

Low resolution structure of subunit b (b22–156) of Escherichia coli F1FO ATP synthase in solution and the b−δ assembly

J. Torres, Weng Chuan Peng, M. Roessle, 2008, Journal of bioenergetics and biomembranes.

Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI

G. Grüber, A. Harikishore, Kevin Pethe, 2023, Antimicrobial agents and chemotherapy.

Overexpression, purification, enzymatic and microscopic characterization of recombinant mycobacterial F-ATP synthase.

W. Saw, G. Grüber, T. Dick, 2019, Biochemical and biophysical research communications.

ATP/ADP Binding to a Novel Nucleotide Binding Domain of the Reticulocyte-binding Protein Py235 of Plasmodium yoelii*

G. Grüber, P. Preiser, C. Hunke, 2008, Journal of Biological Chemistry.

Subunit F modulates ATP binding and migration in the nucleotide-binding subunit B of the A1AO ATP synthase of Methanosarcina mazei Gö1

C. Verma, G. Grüber, S. Gayen, 2012, Journal of Bioenergetics and Biomembranes.

Effect of Ser392 phosphorylation on the structure and dynamics of the polybasic domain of ADP ribosylation factor nucleotide site opener protein: a molecular simulation study.

Chandra S Verma, Gerhard Grüber, C. Verma, 2013, Biochemistry.

The structure of subunit E of the Pyrococcus horikoshii OT3 A-ATP synthase gives insight into the elasticity of the peripheral stalk.

G. Grüber, A. M. Balakrishna, C. Hunke, 2012, Journal of molecular biology.

Extended structure of rat islet amyloid polypeptide in solution.

Lei Wei, G. Grüber, Y. Mu, 2015, Advances in experimental medicine and biology.

Crystal Structure of Subunits D and F in Complex Gives Insight into Energy Transmission of the Eukaryotic V-ATPase from Saccharomyces cerevisiae*♦

G. Grüber, S. Basak, A. M. Balakrishna, 2014, The Journal of Biological Chemistry.

The DNA uptake ATPase PilF of Thermus thermophilus: a reexamination of the zinc content

V. Müller, G. Grüber, D. Nies, 2013, Extremophiles.

Disk-like nanojets with steerable trajectory using platinum nozzle nanoengines

Jianmin Miao, Gerhard Grüber, Liangxing Hu, 2016 .

NMR studies reveal a novel grab and release mechanism for efficient catalysis of the bacterial 2‐Cys peroxiredoxin machinery

F. Eisenhaber, G. Wagner, B. Eisenhaber, 2015, The FEBS journal.

Atomic insights of an up and down conformation of the Acinetobacter baumannii F1‐ATPase subunit ε and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis

W. Saw, G. Grüber, Joon Shin, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity

S. Vasudevan, W. Saw, G. Grüber, 2019, FEBS letters.

Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery

G. Grüber, A. Harikishore, Kevin Pethe, 2023, Expert opinion on drug discovery.

Naturally-occurring polymorphisms in QcrB are responsible for resistance to Telacebec in Mycobacterium abscessus.

S. Shin, G. Grüber, W. Koh, 2019, ACS infectious diseases.

Self-association and conformational variation of NS5A domain 1 of hepatitis C virus.

N. Cho, G. Grüber, H. Yoon, 2018, The Journal of general virology.

Structure of the nucleotide-binding subunit B of the energy producer A1A0 ATP synthase in complex with adenosine diphosphate.

G. Grüber, Anil Kumar, M. Manimekalai, 2008, Acta crystallographica. Section D, Biological crystallography.

Crystallographic and enzymatic insights into the mechanisms of Mg-ADP inhibition in the A1 complex of the A1AO ATP synthase.

G. Grüber, Dhirendra Singh, 2018, Journal of structural biology.

Three-dimensional Organization of the Archaeal A1-ATPase from Methanosarcina mazei Gö1*

M. Radermacher, V. Müller, G. Grüber, 2004, Journal of Biological Chemistry.

Cryo-EM structure of the Mycobacterium abscessus F1-ATPase.

G. Grüber, Chui-Fann Wong, C. Leow, 2023, Biochemical and biophysical research communications.

Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ

V. Müller, Dennis Litty, G. Grüber, 2021, Antibiotics.

The Unique C-Terminal Extension of Mycobacterial F-ATP Synthase Subunit α Is the Major Contributor to Its Latent ATP Hydrolysis Activity

G. Grüber, Chui-Fann Wong, 2020, Antimicrobial Agents and Chemotherapy.

Structure and subunit arrangement of Mycobacterial F1FO ATP synthase and novel features of the unique mycobacterial subunit δ.

P. Bond, G. Grüber, S. Bhushan, 2019, Journal of structural biology.

Deletion of a unique loop in the mycobacterial F‐ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis‐driven H+ pumping

G. Grüber, T. Dick, Subhashri Kundu, 2016, The FEBS journal.

The FGFR inhibitor PD173074 binds to the C‐terminus of oncofetal HMGA2 and modulates its DNA‐binding and transcriptional activation functions

R. Schäfer, G. Grüber, Joon Shin, 2023, FEBS letters.

Identification of critical residues of subunit H in its interaction with subunit E of the A‐ATP synthase from Methanocaldococcus jannaschii

G. Grüber, S. Gayen, A. M. Balakrishna, 2008, The FEBS journal.

1H, 13C, and 15N resonance assignments of subunit F of the A1AO ATP synthase from Methanosarcina mazei Gö1

G. Grüber, S. Gayen, H. Yoon, 2007, Biomolecular NMR assignments.

H , 13 C , and 15 N resonance assignments of subunit F of the A 1 A O ATP synthase from Methanosarcina mazei Gö 1

G. Grüber, H. Yoon, G. Biuković, 2018 .

ATP synthase from Methanosarcina mazei Gö 1 Shovanlal Gayen ∙ Subramanian Vivekanandan ∙

G. Grüber, H. Yoon, G. Biuković, 2017 .

A1AO ATP synthase from Methanosarcina mazei Gö1

G. Grüber, H. Yoon, 2006 .

Cross-talk in the A1-ATPase from Methanosarcina mazei Gö1 Due to Nucleotide Binding*

V. Müller, G. Grüber, M. Koch, 2002, The Journal of Biological Chemistry.

Structural Insights into the A1 ATPase from the archaeon, Methanosarcina mazei Gö1.

D. Svergun, H. Schägger, V. Müller, 2001, Biochemistry.