J. Radolf

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Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I

O. Vinogradova, Arvind Anand, M. LeDoyt, 2015, The Journal of Biological Chemistry.

Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle

R. Iyer, I. Schwartz, J. Radolf, 2007, Molecular microbiology.

CD14 Signaling Restrains Chronic Inflammation through Induction of p38-MAPK/SOCS-Dependent Tolerance

B. Sahay, J. Radolf, C. H. Eggers, 2009, PLoS pathogens.

CD14 Modulates PI3K/AKT/p38-MAPK Licensing of Negative Regulators of TLR Signaling to Restrain Chronic Inflammation

B. Sahay, J. Radolf, C. H. Eggers, 2008 .

Distinct from That Used by Lipopolysaccharide Monocytic Cells via a CD 14-Dependent Pathway Lipoproteins and Synthetic Lipopeptides Activate Borrelia burgdorferi and Treponema pallidum

J. Radolf, R. Ulevitch, J. Pugin, 1998 .

Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide.

J. Radolf, R. Ulevitch, J. Pugin, 1998, Journal of immunology.

Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B

D. Harrich, J. Radolf, M. Norgard, 1996, Infection and immunity.

transcriptional activator NF-kappa B . lipopolysaccharide but involves the proceeds via a pathway distinct from that of lipoproteins and synthetic lipopeptides Treponema pallidum and Borrelia burgdorferi Activation of human monocytic cells

D. Harrich, J. Radolf, M. Norgard, 1996 .

Localization of outer surface proteins A and B in both the outer membrane and intracellular compartments of Borrelia burgdorferi

A. McDowall, J. Radolf, M. Norgard, 1991, Journal of bacteriology.

Surface Immunolabeling and Consensus Computational Framework To Identify Candidate Rare Outer Membrane Proteins of Treponema pallidum

D. L. Cox, Daniel C. Desrosiers, A. Luthra, 2010, Infection and Immunity.

Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes

Arvind Anand, J. Radolf, Binu Shrestha, 2016, BMC Microbiology.

The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices*

Daniel C. Desrosiers, Arvind Anand, A. Luthra, 2011, The Journal of Biological Chemistry.

Treponema pallidum, lipoproteins, and synthetic lipoprotein analogues induce human immunodeficiency virus type 1 gene expression in monocytes via NF-kappaB activation.

R. Gaynor, D. Harrich, J. Radolf, 1998, The Journal of infectious diseases.

Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophages.

L. Davis, J. Radolf, M. Levi, 1995, Journal of immunology.

Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy

J. Radolf, M. Norgard, D. Akins, 1994, Journal of bacteriology.

Role of outer membrane architecture in immune evasion by Treponema pallidum and Borrelia burgdorferi.

J. Radolf, 1994, Trends in microbiology.

Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete

Jeffrey D. Jones, J. D. Jones, J. Radolf, 1995, Infection and immunity.

Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection

D. L. Cox, J. Radolf, S. Porcella, 1997, Infection and immunity.

Major integral membrane protein immunogens of Treponema pallidum are proteolipids

J. Radolf, M. Norgard, A. L. Erwin, 1989, Infection and immunity.

The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein

J. Radolf, M. Norgard, M. Swancutt, 1990, Infection and immunity.

Digoxigenin-ampicillin conjugate for detection of penicillin-binding proteins by chemiluminescence

J. Radolf, J. Belisle, M. Norgard, 1994, Antimicrobial Agents and Chemotherapy.

Lyme Disease in Humans.

F. Strle, J. Radolf, J. Lemieux, 2020, Current issues in molecular biology.

LYME DISEASE AND RELAPSING FEVER SPIROCHETES

J. Radolf, 2020 .

Decorin-Binding Protein A (DbpA) of Borrelia burgdorferi Is Not Protective When Immunized Mice Are Challenged via Tick Infestation and Correlates with the Lack of DbpA Expression by B. burgdorferi in Ticks

J. Radolf, S. Wikel, M. Caimano, 2000, Infection and Immunity.

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Robert M. Waterhouse, Gloria I. Giraldo-Calderón, Daniel R. Caffrey, 2016, Nature Communications.

Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114

J. Radolf, M. Norgard, A. Clausell, 1988, Infection and immunity.

Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis

M. LeDoyt, A. Luthra, J. Radolf, 2020, PLoS pathogens.

Cyclic di-GMP Modulates Gene Expression in Lyme Disease Spirochetes at the Tick-Mammal Interface To Promote Spirochete Survival during the Blood Meal and Tick-to-Mammal Transmission

M. Cassera, J. Radolf, M. Caimano, 2015, Infection and Immunity.

The Treponema pallidum Outer Membrane.

J. Radolf, Sanjiv Kumar, 2017, Current topics in microbiology and immunology.

Assessment of the Kinetics of Treponema pallidum Dissemination into Blood and Tissues in Experimental Syphilis by Real-Time Quantitative PCR

L. Jagodzinski, N. Michael, J. Radolf, 2007, Infection and Immunity.

Dermal inflammation elicited by synthetic analogs of Treponema pallidum and Borrelia burgdorferi lipoproteins

J. Radolf, M. Norgard, J. Richardson, 1995, Infection and immunity.

Virulent Treponema pallidum promotes adhesion of leukocytes to human vascular endothelial cells

N. Oppenheimer-Marks, J. Radolf, M. Norgard, 1994, Infection and immunity.

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

Y. Ruan, O. Luo, J. Radolf, 2019, bioRxiv.

Periapical lesion progression with controlled microbial inoculation in a type I diabetic mouse model.

Qiang Zhu, J. Radolf, J. Barry, 2002, Journal of endodontics.

Effect of primary immunization on pulmonary clearance of nontypable Haemophilus influenzae.

J. Radolf, E. Hansen, G. Toews, 1989, American journal of respiratory cell and molecular biology.

Evaluation of molecular methodologies and rabbit infectivity testing for the diagnosis of congenital syphilis and neonatal central nervous system invasion by Treponema pallidum.

P. Sánchez, J. Radolf, E. Grimprel, 1993, The Journal of infectious diseases.

Sensitive detection of Treponema pallidum by using the polymerase chain reaction

J. Radolf, E. Grimprel, M. Norgard, 1991, Journal of clinical microbiology.

Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid

P. Sánchez, J. Radolf, G. Mccracken, 1991, Journal of clinical microbiology.

Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell binding

J. Radolf, J. Leong, M. Caimano, 2003, Molecular microbiology.

Coevolution of Markers of Innate and Adaptive Immunity in Skin and Peripheral Blood of Patients with Erythema Migrans

P. Krause, J. Radolf, M. Caimano, 2003, The Journal of Immunology.

Blood of Patients with Erythema Migrans Adaptive Immunity in Skin and Peripheral Coevolution of Markers of Innate and

P. Krause, J. Radolf, M. Caimano, 2003 .

Virulent Treponema pallidum activates human vascular endothelial cells.

N. Oppenheimer-Marks, J. Radolf, E. Hansen, 1992, The Journal of infectious diseases.

Isolation of integral membrane proteins by phase partitioning with Triton X-114.

J. Radolf, J. Brusca, 1994, Methods in enzymology.

The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

L. Bockenstedt, A. Luthra, J. Radolf, 2019, Front. Microbiol..

Borrelia : molecular biology, host interaction and pathogenesis

J. Radolf, D. Samuels, 2010 .

Molecular and Evolutionary Characterization of the cp32/18 Family of Supercoiled Plasmids in Borrelia burgdorferi297

J. Radolf, M. Caimano, M. Clawson, 2000, Infection and Immunity.

Chemiluminescent analysis of Borrelia burgdorferi penicillin-binding proteins using ampicillin conjugated to digoxigenin.

J. Radolf, S. Baker, M. Norgard, 1995, Microbial pathogenesis.

Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter

J. Radolf, A. Dey, M. Caimano, 2017, mBio.

Structural Modeling and Physicochemical Characterization Provide Evidence that P66 Forms a β-Barrel in the Borrelia burgdorferi Outer Membrane

Arvind Anand, A. Luthra, J. Radolf, 2013, Journal of bacteriology.

Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family

M. Li, J. Radolf, S. Porcella, 1996, Journal of bacteriology.

Molecular approaches to improved syphilis serodiagnosis

J. Radolf, R. D. Isaacs, 1989 .

Role of disulfide bonds in the oligomeric structure and protease resistance of recombinant and native Treponema pallidum surface antigen 4D

T. Fehniger, J. Radolf, M. Lovett, 1987, Journal of bacteriology.

Antigenic interrelationship between endoflagella of Treponema phagedenis biotype Reiter and Treponema pallidum (Nichols): molecular characterization of endoflagellar proteins

J. Radolf, D. R. Blanco, M. Lovett, 1986, Infection and immunity.

The surface of virulent Treponema pallidum: resistance to antibody binding in the absence of complement and surface association of recombinant antigen 4D

T. Fehniger, J. Radolf, M. Lovett, 1986, Infection and immunity.

Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins

J. Radolf, J. Belisle, M. Brandt, 1994, Journal of bacteriology.

Binding Proteins by Chemiluminescence

J. Radolf, J. Belisle, M. Norgard, 2003 .

CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi

J. M. Iglesias-Pedraz, J. Radolf, J. Cervantes, 2012, Proceedings of the National Academy of Sciences.

Identification of residues within ligand‐binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment

Daniel C. Desrosiers, J. Radolf, R. Marconi, 2010, Molecular microbiology.

Local Production of IFN-γ by Invariant NKT Cells Modulates Acute Lyme Carditis1

J. Radolf, T. Bates, J. Anguita, 2009, The Journal of Immunology.

Activation of human monocytic cells by Borrelia burgdorferi and Treponema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins.

J. Radolf, E. Lien, M. Caimano, 1999, Journal of immunology.

Lyme Arthritis Synovial γδ T Cells Respond to Borrelia burgdorferi Lipoproteins and Lipidated Hexapeptides

J. Radolf, L. Sigal, R. Budd, 1998, The Journal of Immunology.

Borrelia burgdorferi strain-specific Osp C-mediated immunity in mice

Ruth R. Montgomery, E. Fikrig, L. Bockenstedt, 1997, Infection and immunity.

Structural and antigenic conservation of the P2 porin protein among strains of Haemophilus influenzae type b

C. Slaughter, J. Radolf, K. Orth, 1989, Infection and immunity.

A diffusible cytotoxin of Haemophilus ducreyi.

R. Munson, J. Radolf, E. Hansen, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Diagnosis of Babesiosis Using an Immunoblot Serologic Test

A. Spielman, P. Krause, J. Radolf, 2001, Clinical Diagnostic Laboratory Immunology.

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis1

D. Golenbock, J. Radolf, J. Belisle, 2001, The Journal of Immunology.

Mycobacterium tuberculosis Antigen Processing by 19-kDa Lipoprotein of Macrophage Class II MHC Expression and Toll-Like Receptor 2-Dependent Inhibition of Boom and

D. Golenbock, J. Radolf, J. Belisle, 2001 .

Virulent Treponema pallidum, lipoprotein, and synthetic lipopeptides induce CCR5 on human monocytes and enhance their susceptibility to infection by human immunodeficiency virus type 1.

R. Koup, J. Radolf, D. Wilkinson, 2000, The Journal of infectious diseases.

The major outer membrane protein of Haemophilus ducreyi consists of two OmpA homologs

J. Radolf, E. Hansen, J. Klesney-Tait, 1997, Journal of bacteriology.

Use of electroporation to construct isogenic mutants of Haemophilus ducreyi

S. E. Thomas, J. Radolf, E. Hansen, 1992, Journal of bacteriology.

Treponema pallidum in Gel Microdroplets: A Method for Topological Analysis of BamA (TP0326) and Localization of Rare Outer Membrane Proteins.

Arvind Anand, A. Luthra, J. Radolf, 2015, Methods in molecular biology.

Haemophilus ducreyi in an animal model. is involved in virulence expression by A hemoglobin-binding outer membrane protein

J. Radolf, E. Hansen, S. Porcella, 2013 .

Antigenic evidence for simultaneous expression of two different lipooligosaccharides by some strains of Haemophilus influenzae type b

J. Radolf, E. Hansen, G. Mccracken, 1989, Infection and immunity.

Treponema pallidum in gel microdroplets: a novel strategy for investigation of treponemal molecular architecture

D. L. Cox, J. Radolf, S. Porcella, 1995, Molecular microbiology.

Limited surface exposure of Borrelia burgdorferi outer surface lipoproteins.

D. L. Cox, J. Radolf, M. Norgard, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The antigenic interrelationship between the endoflagella of Treponema phagedenis biotype Reiter and Treponema pallidum Nichols strain. I. Treponemicidal activity of cross-reactive endoflagellar antibodies against T. pallidum.

J. Radolf, D. R. Blanco, M. Lovett, 1986, Journal of immunology.

The 47-kDa major lipoprotein immunogen of Treponema pallidum is a penicillin-binding protein with carboxypeptidase activity.

J. Radolf, M. Norgard, L. Weigel, 1994, Proceedings of the National Academy of Sciences of the United States of America.

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

Kelika A. Konda, Daniel L. Pfalmer, J. Klausner, 2022, bioRxiv.

Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum

J. Radolf, N. Agabian, G. Newport, 1989, Infection and immunity.

Treponema pallidum and the quest for outer membrane proteins

J. Radolf, 1995, Molecular microbiology.

MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis

C. Zeiss, E. Fikrig, L. Bockenstedt, 2013, PloS one.

Borrelia burgdorferi transcriptome in the central nervous system of non-human primates

E. Fikrig, S. Narasimhan, J. Radolf, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Correction: Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

S. Norris, J. Radolf, A. Wolfe, 2010, PLoS Pathogens.

Properties of an ordered ring structure formed by recombinant Treponema pallidum surface antigen 4D

T. Fehniger, J. Radolf, M. Lovett, 1986, Journal of bacteriology.

A plasmid‐encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host

S. Norris, J. Howell, J. Radolf, 2003, Molecular microbiology.

Clonal Polymorphism of Borrelia burgdorferi Strain B31 MI: Implications for Mutagenesis in an Infectious Strain Background

J. Bono, T. Schwan, J. Radolf, 2002, Infection and Immunity.

Release of Toll-Like Receptor-2-Activating Bacterial Lipoproteins in Shigella flexneri Culture Supernatants

J. Radolf, A. Zychlinsky, A. Aliprantis, 2001, Infection and Immunity.

A mgl-like operon in Treponema pallidum, the syphilis spirochete.

J. Radolf, S. Porcella, C. Penn, 1996, Gene.

Cloning and expression in Escherichia coli of the gene encoding the heat-modifiable major outer membrane protein of Haemophilus influenzae type b

S. Leachman, J. Radolf, E. Hansen, 1987, Infection and immunity.

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

J. Radolf, B. Stevenson, M. Caimano, 2012, Nature Reviews Microbiology.

Pathogen specificity of Treponema pallidum subsp. pallidum integral membrane proteins identified by phase partitioning with Triton X-114

J. Radolf, M. Norgard, J. D. Radolf, 1988, Infection and immunity.

Genetic and physicochemical characterization of the recombinant DNA-derived 47-kilodalton surface immunogen of Treponema pallidum subsp. pallidum

S. Sell, J. Radolf, P. Hsu, 1988, Infection and immunity.

Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct.

B. Beutler, J. Radolf, P. Thompson, 1991, Journal of immunology.

Outer surface lipoproteins of Borrelia burgdorferi activate vascular endothelium in vitro

J. Radolf, M. Furie, T. Sellati, 1996, Infection and immunity.

Identification of loci critical for replication and compatibility of a Borrelia burgdorferi cp32 plasmid and use of a cp32‐based shuttle vector for the expression of fluorescent reporters in the Lyme disease spirochaete

J. Radolf, M. Caimano, M. Clawson, 2002, Molecular microbiology.

Cloning and sequencing of the gene encoding the Cu,Zn-superoxide dismutase of Haemophilus ducreyi.

D. Hassett, J. Radolf, E. Hansen, 1996, Gene.

, the Agent of Lyme Disease burgdorferi Borrelia Inflammatory Response to Signaling through CD14 Attenuates the

M. R. Benhnia, J. Radolf, S. Goyert, 2005 .

Pathogenesis of syphilis.

J. Radolf, S. Lukehart, K. Hazlett, 2006 .

Cellular Immunity, but Not Gamma Interferon, Is Essential for Resolution of Babesia microti Infection in BALB/c Mice

P. Krause, J. Radolf, S. Wikel, 2002, Infection and Immunity.

Coevolution of Markers of Innate and Adaptive Immunity in Skin and Peripheral Blood of Patients with Erythema Migrans 12

P. Krause, J. Radolf, M. Caimano, 2003, The Journal of Immunology.

The Cutaneous Response in Humans to Treponema pallidum Lipoprotein Analogues Involves Cellular Elements of Both Innate and Adaptive Immunity1

L. Picker, J. Radolf, P. Bergstresser, 2001, The Journal of Immunology.

Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue

J. Radolf, S. Porcella, D. Shevchenko, 1995, Molecular microbiology.

Penicillin-binding proteins and peptidoglycan of Treponema pallidum subsp. pallidum

C. Slaughter, J. Radolf, M. Norgard, 1989, Infection and immunity.

Unusual manifestations of secondary syphilis and abnormal humoral immune response to Treponema pallidum antigens in a homosexual man with asymptomatic human immunodeficiency virus infection.

J. Radolf, R. Kaplan, 1988, Journal of the American Academy of Dermatology.

Secondary Syphilis in Cali, Colombia: New Concepts in Disease Pathogenesis

D. L. Cox, L. Jagodzinski, J. Radolf, 2010, PLoS neglected tropical diseases.

Secondary syphilis in persons infected with and not infected with HIV-1: a comparative immunohistologic study.

C. Cockerell, J. Radolf, M. Chiu, 1999, The American Journal of dermatopathology.

Clinical Manifestations of Early Syphilis by HIV Status and Gender: Results of the Syphilis and HIV Study

J. Radolf, M. Augenbraun, A. Rompalo, 2001, Sexually transmitted diseases.

Treponema pallidum elicits innate and adaptive cellular immune responses in skin and blood during secondary syphilis: a flow-cytometric analysis.

J. Radolf, N. Saravia, J. Salazar, 2007, The Journal of infectious diseases.

The immune response to infection with Treponema pallidum, the stealth pathogen.

J. Radolf, K. Hazlett, J. Salazar, 2002, Microbes and infection.

Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products*

D. Golenbock, J. Radolf, T. Espevik, 1999, The Journal of Biological Chemistry.

A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection. The Syphilis and HIV Study Group.

Steven C. Johnson, J. Radolf, G. Bolan, 1997, The New England journal of medicine.

Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum.

J. Radolf, M. Norgard, W. Schulz, 1989, Proceedings of the National Academy of Sciences of the United States of America.

A critical appraisal of "chronic Lyme disease".

H Artsob, J S Dumler, Susan O'Connell, 2007, The New England journal of medicine.

Southwestern Internal Medicine Conference: brucellosis: don't let it get your goat!

J. Radolf, 1994, The American journal of the medical sciences.

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen

Arvind Anand, J. Radolf, X. F. Yang, 2016, Nature Reviews Microbiology.

Pathogenic Treponema: molecular and cellular biology.

J. Radolf, S. Lukehart, 2006 .

The oral spirochetes: their ecology and role in the pathogenesis of periodontal disease.

J. Radolf, S. Holt, J. Ebersole, 2006 .

Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum

D. L. Cox, Daniel C. Desrosiers, J. Radolf, 2010, Proceedings of the National Academy of Sciences.

A temperature-dependent rabbit model for production of dermal lesions by Haemophilus ducreyi.

J. Radolf, E. Hansen, B. Purcell, 1991, The Journal of infectious diseases.

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.

P. Godowski, J. Radolf, A. Zychlinsky, 1999, Science.

Lipid modification of the 15 kilo Dalton major membrane immunogen of Treponema pallidum

J. Radolf, M. Swancutt, B. Purcell, 1990, Molecular microbiology.

The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks

E. Fikrig, Daniel C. Desrosiers, J. Radolf, 2007, Molecular microbiology.

Discrimination of bacterial lipoproteins by Toll-like receptor 6.

S. Akira, K. Takeda, T. Kawai, 2001, International immunology.

IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages

M. LeDoyt, J. Radolf, J. Cervantes, 2017, Front. Immunol..

Human IgG antibodies to Pseudomonas aeruginosa core lipopolysaccharide determinants are detected in chronic but not acute pseudomonas infection.

L. S. Young, M. Jacobson, J. Radolf, 1987, Scandinavian journal of infectious diseases.

Acylation of the 47-kilodalton major membrane immunogen of Treponema pallidum determines its hydrophobicity

C. Slaughter, J. Radolf, M. Norgard, 1989, Infection and immunity.

Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins

J. Radolf, M. Norgard, M. Brandt, 1990, Infection and immunity.

Treponema pallidum rare outer membrane proteins: analysis of mobility by freeze-fracture electron microscopy

J. Radolf, M. Norgard, K. Bourell, 1994, Journal of bacteriology.

Outcomes from re-treatment and cerebrospinal fluid analyses in syphilis patients who had serological non-response or lack of seroreversion after initial therapy.

J. Radolf, A. Seña, Ligang Yang, 2020, Sexually transmitted diseases.

Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.

A. Luthra, M. Malkowski, J. Radolf, 2015, Journal of structural biology.

Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

B. Sahay, J. Radolf, J. Cervantes, 2011, Proceedings of the National Academy of Sciences.

A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples

J. Radolf, J. Parr, Heping Zheng, 2022, Nature Communications.

IMMUNIZATION OF RABBITS SURFACE ANTIGEN 4D ALTERS WITH RECOMBINANT Treponema patlidurn THE COURSE OF EXPERIMENTAL

T. Fehniger, J. Radolf, D. R. Blanco, 1988 .

Serodiagnosis of syphilis by enzyme-linked immunosorbent assay with purified recombinant Treponema pallidum antigen 4D.

T. Fehniger, J. Radolf, M. Lovett, 1986, The Journal of infectious diseases.

Native surface association of a recombinant 38-kilodalton Treponema pallidum antigen isolated from the Escherichia coli outer membrane

T. Fehniger, J. Radolf, A. Walfield, 1986, Infection and immunity.

TP0453, a Concealed Outer Membrane Protein of Treponema pallidum, Enhances Membrane Permeability

D. L. Cox, R. Brasseur, Daniel C. Desrosiers, 2005, Journal of bacteriology.

The Tprk Protein of Treponema pallidum Is Periplasmic and Is Not a Target of Opsonic Antibody or Protective Immunity

D. L. Cox, Tung T. Nguyen, J. Radolf, 2001, The Journal of experimental medicine.

Immunization of rabbits with recombinant Treponema pallidum surface antigen 4D alters the course of experimental syphilis.

T. Fehniger, J. Radolf, D. R. Blanco, 1988, Journal of immunology.

Identification of tandem genes involved in lipooligosaccharide expression by Haemophilus ducreyi

J. Radolf, E. Hansen, A. Joffe, 1997, Infection and immunity.

Znu Is the Predominant Zinc Importer in Yersinia pestis during In Vitro Growth but Is Not Essential for Virulence

Daniel C. Desrosiers, J. Radolf, R. Perry, 2010, Infection and Immunity.

Disease-specific diagnosis of coinfecting tickborne zoonoses: babesiosis, human granulocytic ehrlichiosis, and Lyme disease.

S. Telford, A. Spielman, V. Sikand, 2002, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The general transition metal (Tro) and Zn2+ (Znu) transporters in Treponema pallidum: analysis of metal specificities and expression profiles

D. L. Cox, Daniel C. Desrosiers, J. Radolf, 2007, Molecular microbiology.

The Treponema pallidum tro Operon Encodes a Multiple Metal Transporter, a Zinc-dependent Transcriptional Repressor, and a Semi-autonomously Expressed Phosphoglycerate Mutase*

M. Maguire, J. Radolf, D. Kehres, 2003, Journal of Biological Chemistry.

Treponema and Brachyspira, Human Host-Associated Spirochetes

D. L. Cox, J. Radolf, A. Seña, 2011 .

Identification of homologs for thioredoxin, peptidyl prolyl cis-trans isomerase, and glycerophosphodiester phosphodiesterase in outer membrane fractions from Treponema pallidum, the syphilis spirochete

M. Li, J. Radolf, D. Shevchenko, 1997, Infection and immunity.

Molecular characterization and cellular localization of TpLRR, a processed leucine-rich repeat protein of Treponema pallidum, the syphilis spirochete

D. L. Cox, M. Li, J. Radolf, 1997, Journal of bacteriology.

Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity

J. Radolf, M. Norgard, D. Akins, 1993, Infection and immunity.

The outer membrane, not a coat of host proteins, limits antigenicity of virulent Treponema pallidum

D. L. Cox, A. McDowall, J. Radolf, 1992, Infection and immunity.

Expression in Escherichia coli of the 37-kilodalton endoflagellar sheath protein of Treponema pallidum by use of the polymerase chain reaction and a T7 expression system

J. Radolf, R. D. Isaacs, 1990, Infection and immunity.

Molecular cloning and characterization of the 15-kilodalton major immunogen of Treponema pallidum

J. Radolf, E. Robinson, M. Norgard, 1989, Infection and immunity.

Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum

C. Slaughter, S. Sell, J. Radolf, 1989, Infection and immunity.

A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy

J. Radolf, J. Tucker, A. Seña, 2015, BMC Infectious Diseases.

Increasing health burden of human babesiosis in endemic sites.

S. Telford, A. Spielman, V. Sikand, 2003, The American journal of tropical medicine and hygiene.

Insertion of fluorescent fatty acid probes into the outer membranes of the pathogenic spirochaetes Treponema pallidum and Borrelia burgdorferi.

D. L. Cox, J. Radolf, 2001, Microbiology.

Phagocytosis of Borrelia burgdorferi and Treponema pallidum Potentiates Innate Immune Activation and Induces Gamma Interferon Production

J. Radolf, C. H. Eggers, M. Moore, 2007, Infection and Immunity.

Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete

Jeffrey D. Jones, J. D. Jones, J. Radolf, 1995, Infection and immunity.

Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle

J. Radolf, Ashley M Groshong, Melissa A McLain, 2021, PLoS pathogens.

Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes

Arvind Anand, J. Radolf, Binu Shrestha, 2016, BMC Microbiology.

Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks.

J. Radolf, U. Pal, C. Wolgemuth, 2009, The Journal of clinical investigation.

Characterization of the Stringent Response and relBbu Expression in Borrelia burgdorferi

J. Radolf, E. Dobrikova, M. Caimano, 2003, Journal of bacteriology.

Identification and transcriptional analysis of a Treponema pallidum operon encoding a putative ABC transport system, an iron-activated repressor protein homolog, and a glycolytic pathway enzyme homolog.

G. Weinstock, S. Norris, J. Hardham, 1997, Gene.

Immune Evasion and Recognition of the Syphilis Spirochete in Blood and Skin of Secondary Syphilis Patients: Two Immunologically Distinct Compartments

J. Radolf, J. Cervantes, R. Cartun, 2012, PLoS neglected tropical diseases.

Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides.

J. Radolf, L. Sigal, R. Budd, 1998, Journal of immunology.

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

V. Uversky, A. Luthra, J. Radolf, 2021, Journal of bacteriology.

Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Arvind Anand, M. LeDoyt, J. Radolf, 2018, mBio.

Structural modeling of the Treponema pallidum OMPeome : a roadmap for 1 deconvolution of syphilis pathogenesis and development of a syphilis vaccine 2 3 Running Title : Structural modeling of the Treponema pallidum OMPeome 4 5

V. Uversky, A. Luthra, J. Radolf, 2021 .

Xenodiagnosis for posttreatment Lyme disease syndrome: resolving the conundrum or adding to it?

L. Bockenstedt, J. Radolf, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Neelaredoxin, an Iron-binding Protein from the Syphilis Spirochete, Treponema pallidum, Is a Superoxide Reductase*

L. Benson, Stephen Naylor, C. Krebs, 2000, The Journal of Biological Chemistry.

Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays

S. Casjens, I. Schwartz, J. Radolf, 2003, Infection and Immunity.

Borrelia burgdorferi gene expression profiling with membrane-based arrays.

S. Casjens, I. Schwartz, J. Radolf, 2002, Methods in enzymology.

Decorin-Binding Protein of Borrelia burgdorferi Is Encoded within a Two-Gene Operon and Is Protective in the Murine Model of Lyme Borreliosis

J. Radolf, S. Porcella, M. Norgard, 1998, Infection and Immunity.

Alternate Sigma Factor RpoS Is Required for the In Vivo-Specific Repression of Borrelia burgdorferi Plasmid lp54-Borne ospA and lp6.6 Genes

J. Radolf, M. Caimano, C. H. Eggers, 2005, Journal of bacteriology.

Burstain JM, Grimprel E, Lukehart SA, Norgard MV, Radolf JDSensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol 29:62-69

J. Radolf, E. Grimprel, M. Norgard, 1991 .

Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG+-Specific B-Cells in the Rabbit Model of Experimental Syphilis

M. A. Moody, A. Luthra, J. Radolf, 2022, mBio.

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

J. Shupe, J. Radolf, M. Caimano, 2009, PLoS pathogens.

Analysis of Treponema pallidum strains from China using improved methods for whole-genome sequencing from primary syphilis chancres

Yongfei Hu, J. Radolf, J. Parr, 2020, bioRxiv.

A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326

Arvind Anand, M. LeDoyt, A. Luthra, 2015, Journal of bacteriology.

TprC/D (Tp0117/131), a Trimeric, Pore-Forming Rare Outer Membrane Protein of Treponema pallidum, Has a Bipartite Domain Structure

Arvind Anand, M. LeDoyt, Carson Karanian, 2012, Journal of bacteriology.

TP0326, a Treponema pallidum β‐barrel assembly machinery A (BamA) orthologue and rare outer membrane protein

Daniel C. Desrosiers, Arvind Anand, M. LeDoyt, 2011, Molecular microbiology.

Stage‐specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation

R. Iyer, I. Schwartz, A. Luthra, 2015, Molecular microbiology.

RpoS Is Not Central to the General Stress Response in Borrelia burgdorferi but Does Control Expression of One or More Essential Virulence Determinants

J. Radolf, M. Caimano, C. H. Eggers, 2004, Infection and Immunity.

Molecular and Evolutionary Analysis ofBorrelia burgdorferi 297 Circular Plasmid-Encoded Lipoproteins with OspE- and OspF-Like Leader Peptides

J. Radolf, M. Caimano, M. Norgard, 1999, Infection and Immunity.

A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state.

J. Radolf, M. Caimano, M. Norgard, 1998, The Journal of clinical investigation.

Borrelia burgdorferi bba74 Is Expressed Exclusively during Tick Feeding and Is Regulated by Both Arthropod- and Mammalian Host-Specific Signals

R. Iyer, D. Liveris, I. Schwartz, 2009, Journal of bacteriology.

Signaling through CD14 Attenuates the Inflammatory Response to Borrelia burgdorferi, the Agent of Lyme Disease1

M. R. Benhnia, J. Radolf, S. Goyert, 2005, The Journal of Immunology.

Environmental Regulation and Differential Production of Members of the Bdr Protein Family of Borrelia burgdorferi

D. Roberts, J. Radolf, M. Theisen, 2002, Infection and Immunity.

Regulation of OspE-Related, OspF-Related, and Elp Lipoproteins of Borrelia burgdorferi Strain 297 by Mammalian Host-Specific Signals

J. Radolf, S. Wikel, M. Caimano, 2001, Infection and Immunity.

Identification, Characterization, and Expression of Three New Members of the Borrelia burgdorferi Mlp (2.9) Lipoprotein Gene Family

J. Radolf, S. Wikel, M. Caimano, 1999, Infection and Immunity.

Borrelia burgdorferi Requires the Alternative Sigma Factor RpoS for Dissemination within the Vector during Tick-to-Mammal Transmission

J. Radolf, M. Caimano, C. H. Eggers, 2012, PLoS pathogens.

NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi

Chi‐Huey Wong, M. R. Benhnia, S. Crotty, 2008, Proceedings of the National Academy of Sciences.

Membrane topology of Borrelia burgdorferi and Treponema pallidum lipoproteins

J. D. Jones, J. Radolf, M. Norgard, 1995, Infection and immunity.

Borrelia burgdorferi outer surface protein (osp) B expression independent of ospA.

Erol Fikrig, E. Fikrig, J. Radolf, 2004, Microbial pathogenesis.

Phagocytosis of Borrelia burgdorferi, the Lyme Disease Spirochete, Potentiates Innate Immune Activation and Induces Apoptosis in Human Monocytes

J. Radolf, C. H. Eggers, M. Moore, 2007, Infection and Immunity.

Lipoprotein-Dependent and -Independent Immune Responses to Spirochetal Infection

J. Radolf, M. Moore, Thomas G. Kiely, 2005, Clinical Diagnostic Laboratory Immunology.

Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

S. Norris, J. Radolf, A. Wolfe, 2010, PLoS pathogens.

Membrane Topology and Cellular Location of the Treponema pallidum Glycerophosphodiester Phosphodiesterase (GlpQ) Ortholog

D. L. Cox, J. Radolf, D. Shevchenko, 1999, Infection and Immunity.

A hemoglobin-binding outer membrane protein is involved in virulence expression by Haemophilus ducreyi in an animal model

S. E. Thomas, J. Radolf, E. Hansen, 1996, Infection and immunity.

J. Radolf, M. Norgard, D. Akins, 1994, Infection and immunity.

Treponema pallidum, the stealth pathogen, changes, but how?

Daniel C. Desrosiers, J. Radolf, 2009, Molecular microbiology.

Borrelia burgdorferi BBA74, a Periplasmic Protein Associated with the Outer Membrane, Lacks Porin-Like Properties

D. Liveris, I. Schwartz, Daniel C. Desrosiers, 2006, Journal of bacteriology.

The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue

L. Bockenstedt, J. Radolf, H. Fu, 2012, Proceedings of the National Academy of Sciences.

Tromp1, a putative rare outer membrane protein, is anchored by an uncleaved signal sequence to the Treponema pallidum cytoplasmic membrane

D. L. Cox, C. Elkins, J. Radolf, 1997, Journal of bacteriology.

ISOLATION AND MOLECULAR CLONING OF A SECRETED IMMUNOSUPPRESSANT PROTEIN FROM DERMACENTOR ANDERSONI SALIVARY GLAND

M. Palmer, J. Radolf, S. Wikel, 2000, The Journal of parasitology.

Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle

R. Iyer, I. Schwartz, J. Radolf, 2011, PLoS pathogens.

Analysis of Promoter Elements Involved in the Transcriptional Initiation of RpoS-Dependent Borrelia burgdorferi Genes

J. Radolf, M. Caimano, C. H. Eggers, 2004, Journal of bacteriology.

Single-dose prophylaxis against Lyme disease.

R. Nadelman, R. Dattwyler, E. Shapiro, 2007, The Lancet. Infectious diseases.

Risk of acquisition of genital herpes simplex virus type 2 in sex partners of persons with genital herpes: a prospective couple study.

D. Bernstein, J. Radolf, P. Zakowski, 1993, The Journal of infectious diseases.

Serodiagnosis of syphilis in the recombinant era: reversal of fortune.

J. Radolf, K. Hoover, 2011, The Journal of infectious diseases.

Prominent osseous and unusual dermatologic manifestations of early syphilis in two patients with discordant serological statuses for human immunodeficiency virus infection.

J. Radolf, S. Rademacher, 1996, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity

S. Kortagere, Z. Dvořák, J. Radolf, 2022, mBio.

PCR-Based Identification of Bacteria Associated with Endodontic Infections

Qiang Zhu, J. Radolf, J. Barry, 2002, Journal of Clinical Microbiology.

A system for generalized mutagenesis of Haemophilus ducreyi

J. Radolf, E. Hansen, L. Cope, 1995, Infection and immunity.

Use of tissue culture and animal models to identify virulence-associated traits of Haemophilus ducreyi

J. Radolf, E. Hansen, J. Klesney-Tait, 1995, Infection and immunity.

Induction of protective immunity to Haemophilus ducreyi in the temperature-dependent rabbit model of experimental chancroid.

J. Radolf, E. Hansen, L. Cope, 1994, Journal of Immunology.

The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host

Daniel C. Desrosiers, J. Radolf, T. Kariu, 2011, Molecular microbiology.

Detection of Haemophilus ducreyi lipooligosaccharide by means of an immunolimulus assay.

J. Radolf, E. Hansen, L. Cope, 1995, Journal of immunological methods.

Molecular characterization of the presence of Eubacterium spp and Streptococcus spp in endodontic infections.

K. Kum, J. Radolf, J. Barry, 2003, Oral microbiology and immunology.

The major outer sheath protein forms distinct conformers and multimeric complexes in the outer membrane and periplasm of Treponema denticola

O. Vinogradova, Arvind Anand, Robbins Puthenveetil, 2017, Scientific Reports.

The Major Outer Sheath Protein (Msp) of Treponema denticola Has a Bipartite Domain Architecture and Exists as Periplasmic and Outer Membrane-Spanning Conformers

Arvind Anand, M. LeDoyt, A. Luthra, 2013, Journal of bacteriology.

The Treponema denticola Major Sheath Protein Is Predominantly Periplasmic and Has Only Limited Surface Exposure

D. L. Cox, J. Radolf, M. Caimano, 1999, Infection and Immunity.

Viscous dynamics of Lyme disease and syphilis spirochetes reveal flagellar torque and drag.

J. Radolf, C. Wolgemuth, Dhruv Vig, 2013, Biophysical journal.

Two Distinct Mechanisms Govern RpoS-Mediated Repression of Tick-Phase Genes during Mammalian Host Adaptation by Borrelia burgdorferi, the Lyme Disease Spirochete

R. Iyer, D. Liveris, I. Schwartz, 2017, mBio.

Sigma factor selectivity in Borrelia burgdorferi: RpoS recognition of the ospE/ospF/elp promoters is dependent on the sequence of the −10 region

J. Radolf, M. Caimano, C. H. Eggers, 2006, Molecular microbiology.

HrpA, an RNA Helicase Involved in RNA Processing, Is Required for Mouse Infectivity and Tick Transmission of the Lyme Disease Spirochete

J. Radolf, M. Caimano, G. Chaconas, 2013, PLoS pathogens.

Evaluation of the Borrelia burgdorferi BBA64 Protein as a Protective Immunogen in Mice

J. Radolf, M. Caimano, R. Gilmore, 2014, Clinical and Vaccine Immunology.

Chemoprophylaxis against Lyme disease

R. Nadelman, R. Dattwyler, E. Shapiro, 2008 .

Contribution of neelaredoxin to oxygen tolerance by Treponema pallidum.

D. L. Cox, J. Radolf, F. Rusnak, 2002, Methods in enzymology.

BB0844, an RpoS-Regulated Protein, Is Dispensable for Borrelia burgdorferi Infectivity and Maintenance in the Mouse-Tick Infectious Cycle

R. Iyer, I. Schwartz, J. Radolf, 2010, Infection and Immunity.

The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks

Daniel C. Desrosiers, J. Radolf, U. Pal, 2011, Infection and Immunity.

Who is the BosR around here anyway?

J. Radolf, D. Samuels, 2009, Molecular microbiology.

The long strange trip of Borrelia burgdorferi outer‐surface protein C

J. Radolf, M. Caimano, 2008, Molecular microbiology.

Solid-phase synthesis of biologically active lipopeptides as analogs for spirochetal lipoproteins.

J. D. Jones, C. Slaughter, J. Rush, 1994, Peptide research.

Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone

J. Radolf, Yong-Hwan Lee, C. Hasemann, 1999, Nature Structural Biology.

Bull’s eye: Unraveling the medical mystery of Lyme disease

J. Radolf, Justin D. Radolf, 2004 .

The Crystal Structure of Zn(II)-Free Treponema pallidum TroA, a Periplasmic Metal-Binding Protein, Reveals a Closed Conformation

J. Radolf, Yong-Hwan Lee, M. Dorwart, 2002, Journal of bacteriology.

Experimental Assessment of the Roles of Linear Plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the Infectious Cycle

J. Radolf, P. Stewart, P. Rosa, 2004, Infection and Immunity.

Cryo-Electron Tomography Elucidates the Molecular Architecture of Treponema pallidum, the Syphilis Spirochete

D. L. Cox, M. Marko, J. Izard, 2009, Journal of bacteriology.

Development of a biomarker signature using grating-coupled fluorescence plasmonic microarray for diagnosis of MIS-C

J. Graf, J. Radolf, M. Lynes, 2023, Frontiers in Bioengineering and Biotechnology.

A TFIIH-Associated Mediator Head Is a Basal Factor of Small Nuclear Spliced Leader RNA Gene Transcription in Early-Diverged Trypanosomes

F. Asturias, J. Radolf, G. Cai, 2010, Molecular and Cellular Biology.

Anti-tumor necrosis factor-alpha activation of Borrelia burgdorferi spirochetes in antibiotic-treated murine Lyme borreliosis: an unproven conclusion.

A. Steere, J. Bakken, R. Dattwyler, 2007, The Journal of infectious diseases.

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi

A. Luthra, J. Radolf, M. Caimano, 2021, PLoS pathogens.

BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals

J. Radolf, M. Caimano, R. Tokarz, 2023, The Journal of clinical investigation.

Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)

M. A. Moody, J. Radolf, A. Schryvers, 2023, bioRxiv.

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

J. Radolf, M. Caimano, J. Salazar, 2009, PLoS pathogens.

Pulling the trigger on lyme arthritis.

J. Radolf, 2013, The Journal of infectious diseases.

Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays

S. Casjens, I. Schwartz, J. Radolf, 2003, Infection and Immunity.

Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

B. Sahay, J. Radolf, J. Cervantes, 2011, Proceedings of the National Academy of Sciences.

TP0326, a Treponema pallidum β‐barrel assembly machinery A (BamA) orthologue and rare outer membrane protein

Daniel C. Desrosiers, Arvind Anand, M. LeDoyt, 2011, Molecular microbiology.

The Tprk Protein of Treponema pallidum Is Periplasmic and Is Not a Target of Opsonic Antibody or Protective Immunity

D. L. Cox, Tung T. Nguyen, J. Radolf, 2001, The Journal of experimental medicine.

Posttreatment chronic Lyme disease--what it is not.

J. Radolf, 2005, The Journal of infectious diseases.

Clinical and genomic diversity of Treponema pallidum subsp. pallidum: A global, multi-center study of early syphilis to inform vaccine research

J. Radolf, J. Parr, J. Juliano, 2023, medRxiv.

Early syphilis in Guangzhou, China: presentation, molecular detection of Treponema pallidum, and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing

J. Radolf, M. Caimano, Heping Zheng, 2023, medRxiv.

Znu Is the Predominant Zinc Importer in Yersinia pestis during In Vitro Growth but Is Not Essential for Virulence

Daniel C. Desrosiers, J. Radolf, R. Perry, 2010, Infection and Immunity.

MajorIntegral MembraneProtein Immunogensof Treponema pallidum AreProteolipids

J. Radolf, 1989 .