J. Piontek

发表

Probing the cis-arrangement of prototype tight junction proteins claudin-1 and claudin-3.

S. Milatz, J. Piontek, J. Schulzke, 2015, The Biochemical journal.

Assembly of Tight Junction Strands: Claudin-10b and Claudin-3 Form Homo Tetrameric Building Blocks that Polymerise in a Channel-Independent Manner.

J. Piontek, D. Günzel, C. Hempel, 2020, Journal of molecular biology.

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells

J. Piontek, G. Krause, H. Walles, 2017, Stem cell reports.

Structure and function of claudins.

J. Piontek, I. Blasig, G. Krause, 2008, Biochimica et biophysica acta.

Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells

J. Piontek, J. Protze, A. Piontek, 2019, International journal of molecular sciences.

On the self-association potential of transmembrane tight junction proteins

M. Kolbe, J. Piontek, I. Blasig, 2006, Cellular and Molecular Life Sciences CMLS.

Redox-sensitivity of the dimerization of occludin

J. Piontek, I. Blasig, C. Rueckert, 2009, Cellular and Molecular Life Sciences.

Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules

H. Wolburg, J. Piontek, I. Blasig, 2010, Cellular and Molecular Life Sciences.

Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain.

J. Piontek, J. Schulzke, J. Protze, 2018, Biomaterials.

Differential and Regulated Binding of cAMP-dependent Protein Kinase and Protein Kinase C Isoenzymes to Gravin in Human Model Neurons

J. Piontek, R. Brandt, 2003, Journal of Biological Chemistry.

Contact with astroglial membranes induces axonal and dendritic growth of human CNS model neurons and affects the distribution of the growth‐associated proteins MAP1B and GAP43

J. Piontek, R. Brandt, A. Régnier-Vigouroux, 2002, Journal of neuroscience research.

In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization

H. Wolburg, S. Milatz, J. Piontek, 2013, Journal of Cell Science.

Effective Oncoleaking Treatment of Pancreatic Cancer by Claudin-Targeted Suicide Gene Therapy with Clostridium perfringens Enterotoxin (CPE)

J. Piontek, W. Walther, D. Behrens, 2021, Cancers.

Claudins are essential for cell shape changes and convergent extension movements during neural tube closure

N. Greene, J. Piontek, A. Piontek, 2017, Developmental biology.

Claudin‐15 forms a water channel through the tight junction with distinct function compared to claudin‐2

J. Piontek, M. Fromm, D. Günzel, 2020, Acta physiologica.

Molecular architecture and assembly of the tight junction backbone.

J. Piontek, M. Fromm, J. Protze, 2020, Biochimica et biophysica acta. Biomembranes.

Tricellulin forms homomeric and heteromeric tight junctional complexes

J. Piontek, I. Blasig, M. Fromm, 2010, Cellular and Molecular Life Sciences.

Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion

H. Wolburg, J. Piontek, I. Blasig, 2010, Proceedings of the National Academy of Sciences.

Nanoscale segregation of channel and barrier claudins enables paracellular ion flux

V. Haucke, J. Piontek, D. Günzel, 2022, Nature Communications.

The hinge region of the scaffolding protein of cell contacts, zonula occludens protein 1, regulates interacting with various signaling proteins

J. Piontek, I. Blasig, B. Nürnberg, 2012, Journal of cellular biochemistry.

Neurotrophins Differentially Regulate the Survival and Morphological Complexity of Human CNS Model Neurons

J. Piontek, R. Brandt, M. Kempf, 1999, Journal of neurochemistry.

The Oligomerization of the Coiled Coil‐domain of Occluddin Is Redox Sensitive

J. Piontek, I. Blasig, C. Rueckert, 2009, Annals of the New York Academy of Sciences.

Assembly of tight junction is regulated by the antagonism of conventional and novel protein kinase C isoforms.

J. Piontek, I. Blasig, A. Andreeva, 2005, The international journal of biochemistry & cell biology.

Elucidating the principles of the molecular organization of heteropolymeric tight junction strands

H. Rahn, H. Wolburg, J. Piontek, 2011, Cellular and Molecular Life Sciences.

Tight junctions of the proximal tubule and their channel proteins

J. Piontek, M. Fromm, D. Günzel, 2017, Pflügers Archiv - European Journal of Physiology.

In Colon Epithelia, Clostridium perfringens Enterotoxin Causes Focal Leaks by Targeting Claudins Which are Apically Accessible Due to Tight Junction Derangement

J. Piontek, J. Schulzke, M. Fromm, 2017, The Journal of infectious diseases.

A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin

J. Piontek, I. Blasig, E. Krause, 2009, BMC Molecular Biology.

Acute and subchronic effects of Rimcazole (BW 234U), a potential antipsychotic drug, on A9 and A10 dopamine neurons in the rat.

J. Piontek, R. Y. Wang, 1986, Life sciences.

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

J. Piontek, I. Blasig, S. Gringhuis, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tight junction strand formation by claudin‐10 isoforms and claudin‐10a/‐10b chimeras

Rukeia El-Athman, S. Milatz, J. Piontek, 2017, Annals of the New York Academy of Sciences.

Molecular basis of claudin-17 anion selectivity

Marcel P. Conrad, J. Piontek, M. Fromm, 2015, Cellular and Molecular Life Sciences.

Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage

S. Baig, S. Milatz, J. Piontek, 2017, PLoS genetics.

Defective claudin-10 causes a novel variation of HELIX syndrome through compromised tight junction strand assembly

C. Bergmann, Steffen Neuber, J. Piontek, 2021, Genes & diseases.

Molecular and structural transmembrane determinants critical for embedding claudin-5 into tight junctions reveal a distinct four-helix bundle arrangement.

J. Piontek, D. Günzel, J. Protze, 2014, The Biochemical journal.

Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier

B. Engelhardt, J. Piontek, J. McGrath, 2021, Journal of cell science.

Polar and charged extracellular residues conserved among barrier‐forming claudins contribute to tight junction strand formation

H. Wolburg, J. Piontek, D. Günzel, 2017, Annals of the New York Academy of Sciences.

Molecular basis of claudin-17 anion selectivity

Marcel P. Conrad, J. Piontek, M. Fromm, 2015, Cellular and Molecular Life Sciences.

Claudin-3 and Claudin-5 Protein Folding and Assembly into the Tight Junction Are Controlled by Non-conserved Residues in the Transmembrane 3 (TM3) and Extracellular Loop 2 (ECL2) Segments*

H. Wolburg, J. Piontek, D. Günzel, 2014, The Journal of Biological Chemistry.

A cCPE‐based xenon biosensor for magnetic resonance imaging of claudin‐expressing cells

J. Piontek, J. Protze, A. Piontek, 2017, Annals of the New York Academy of Sciences.

Targeting claudin‐overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin

K. Schmid, J. Piontek, J. Protze, 2019, Molecular oncology.

Assembly and function of claudins: Structure-function relationships based on homology models and crystal structures.

J. Piontek, J. Protze, G. Krause, 2015, Seminars in cell & developmental biology.

Claudin-10b cation channels in tight junction strands: Octameric-interlocked pore barrels constitute paracellular channels with low water permeability

J. Piontek, S. Nagarajan, Stanislav Klein, 2023, Computational and structural biotechnology journal.

Tight junction channels claudin‐10b and claudin‐15: Functional mapping of pore‐lining residues

J. Piontek, M. Fromm, D. Günzel, 2022, Annals of the New York Academy of Sciences.

Targeting and alteration of tight junctions by bacteria and their virulence factors such as Clostridium perfringens enterotoxin

J. Piontek, J. Protze, A. Piontek, 2016, Pflügers Archiv - European Journal of Physiology.

Structure and Function of Extracellular Claudin Domains

J. Piontek, I. Blasig, G. Krause, 2009, Annals of the New York Academy of Sciences.

Clinical Significance of Claudin Expression in Oral Squamous Cell Carcinoma

J. Piontek, J. Schulzke, M. Fromm, 2022, International journal of molecular sciences.

Mechanism of Clostridium perfringens Enterotoxin Interaction with Claudin-3/-4 Protein Suggests Structural Modifications of the Toxin to Target Specific Claudins*

J. Piontek, J. Protze, G. Krause, 2011, The Journal of Biological Chemistry.

Visualization and Quantitative Analysis of Reconstituted Tight Junctions Using Localization Microscopy

Manfred Kirchgessner, Christoph Cremer, Hartwig Wolburg, 2012, PloS one.

Determinants contributing to claudin ion channel formation

J. Piontek, M. Fromm, J. Protze, 2012, Annals of the New York Academy of Sciences.

cCPE Fusion Proteins as Molecular Probes to Detect Claudins and Tight Junction Dysregulation in Gastrointestinal Cell Lines, Tissue Explants and Patient-Derived Organoids

J. Piontek, C. Kamphues, M. Schumann, 2023, Pharmaceutics.

Claudin targeting as an effective tool for directed barrier modulation of the viable epidermis

J. Piontek, D. Günzel, J. Brandner, 2022, Annals of the New York Academy of Sciences.

The Investigation of cis- and trans-Interactions Between Claudins

J. Piontek, I. Blasig, R. Haseloff, 2010 .

Probing the cis-arrangement of prototype tight junction proteins claudin-1 and claudin-3.

S. Milatz, J. Piontek, J. Schulzke, 2015, The Biochemical journal.

Tight junctions of the proximal tubule and their channel proteins

J. Piontek, M. Fromm, D. Günzel, 2017, Pflügers Archiv - European Journal of Physiology.