Hongzhe Sun

发表

Metallomics: An integrated science for metals in biology and medicine

Hongzhe Sun, Z. Chai, 2010 .

Metallomics: An integrated biometal science

Hongzhe Sun, R. Ge, Ruiguang Ge, 2009 .

Folic acid conjugated mPEG-PEI600 as an efficient non-viral vector for targeted nucleic acid delivery.

Marie C. M. Lin, H. Kung, Hongzhe Sun, 2012, International journal of pharmaceutics.

Proteomic analysis of the mode of antibacterial action of silver nanoparticles.

Chi-Ming Che, Hongzhe Sun, Qing-Yu He, 2006, Journal of proteome research.

Combination of gallium(iii) with acetate for combating antibiotic resistant Pseudomonas aeruginosa† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures and omics data. See DOI: 10.1039/c9sc01480b

Hongzhe Sun, Yuchuan Wang, Bingjie Han, 2019, Chemical science.

DNA hydrolysis promoted by di- and multi-nuclear metal complexes

Hongzhe Sun, Tianle Zhang, Changlin Liu, 2004 .

NMR studies of metalloproteins.

Hongzhe Sun, Hongyan Li, 2012, Topics in current chemistry.

The effect of the extracellular domain of human copper transporter (hCTR1) on cisplatin activation.

Hongzhe Sun, Hongyan Li, Xinghao Wang, 2011, Angewandte Chemie.

Cell Cycle-Dependent Uptake and Cytotoxicity of Arsenic-Based Drugs in Single Leukemia Cells.

Hongzhe Sun, Haibo Wang, Hongyan Li, 2018, Analytical chemistry.

Unexpectedly Strong Binding of a Large Metal Ion (Bi) to Human Serum Transferrin (*)

P. Sadler, Hongzhe Sun, Hongyan Li, 1996, The Journal of Biological Chemistry.

The First Specific TiIV -Protein Complex: Potential Relevance to Anticancer Activity of Titanocenes.

P. Sadler, Hongzhe Sun, Hongyan Li, 1998, Angewandte Chemie.

N-lobe versus C-lobe complexation of bismuth by human transferrin

P. Sadler, A. Mason, R. Woodworth, 1999 .

Bioinorganic chemistry of bismuth and antimony: target sites of metallodrugs.

Hongzhe Sun, R. Ge, 2007, Accounts of chemical research.

Complexation of antimony (Sb(V)) with guanosine 5'-monophosphate and guanosine 5'-diphospho-D-mannose: formation of both mono- and bis-adducts.

L. Chow, Hongzhe Sun, I. Wong, 2005, Journal of inorganic biochemistry.

Effect of cyclodextrin dimers with bipyridyl and biphenyl linking groups on carboxyl ester hydrolysis catalyzed by zinc complex

Hongzhe Sun, L. Ji, Z. Mao, 2009 .

An effective metallohydrolase model with a supramolecular environment: structures, properties, and activities.

C. Su, Hongzhe Sun, M. Tong, 2007, Chemistry.

Encapsulation of platinum anticancer drugs by apoferritin.

Hongzhe Sun, Zijian Guo, Zhenghao Yang, 2007, Chemical communications.

HFIP-induced structures and assemblies of the peptides from the transmembrane domain 4 of membrane protein Nramp1.

Hongzhe Sun, Chunyu Wang, Fei Li, 2006, Biopolymers.

Metallomic and metalloproteomic strategies in elucidating the molecular mechanisms of metallodrugs.

Hongzhe Sun, Yuchuan Wang, Haibo Wang, 2015, Dalton transactions.

Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2.

Qing‐Yu He, Z. Cai, Hongzhe Sun, 2009, Journal of inorganic biochemistry.

Metal-binding properties of an Hpn-like histidine-rich protein.

Hongzhe Sun, Yibo Zeng, N. Yang, 2011, Chemistry.

Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm†

A. Yan, Hongzhe Sun, Q. Hao, 2020, Chemical science.

Metalloproteomics for Unveiling the Mechanism of Action of Metallodrugs.

Hongzhe Sun, Yuchuan Wang, Hongyan Li, 2019, Inorganic chemistry.

On-line coupling of continuous-flow gel electrophoresis with inductively coupled plasma-mass spectrometry to quantitatively evaluate intracellular metal binding properties of metallochaperones HpHypA and HpHspA in E. coli cells.

Hongzhe Sun, Yuchuan Wang, Hongyan Li, 2015, Metallomics : integrated biometal science.

In-cell NMR: an emerging approach for monitoring metal-related events in living cells.

Hongzhe Sun, Hongyan Li, 2014, Metallomics : integrated biometal science.

Biological Chemistry of Arsenic, Antimony and Bismuth

Hongzhe Sun, 2010 .

Bismuth Complexes Inhibit the SARS Coronavirus†

J. Tanner, Marie C. M. Lin, H. Kung, 2007, Angewandte Chemie.

Microwave synthesis of BiPO4 nanostructures and their morphology-dependent photocatalytic performances.

Hongzhe Sun, Guangfang Li, Rong Chen, 2011, Journal of colloid and interface science.

Rapid reduction of pentavalent antimony by trypanothione: potential relevance to antimonial activation.

L. Chow, Hongzhe Sun, I. Wong, 2003, Chemical communications.

Complexation of Antimony(III) by Trypanothione.

Hongzhe Sun, Siucheong Yan, K. Ding, 2000, Angewandte Chemie.

Selective interaction of Hpn-like protein with nickel, zinc and bismuth in vitro and in cells by FRET.

Hongzhe Sun, Haibo Wang, Yuen-Yan Chang, 2015, Journal of inorganic biochemistry.

Hyperthermia Selectively Destabilizes Fusion Oncoproteins

Zhang, Cheng, Xiaodong, 2021 .

Ranitidine bismuth(III) citrate

P. Sadler, Hongzhe Sun, 1995 .

Exploration into the nickel ‘microcosmos’ in prokaryotes

Hongzhe Sun, W. Xia, Hongyan Li, 2016 .

A zinc-binding site by negative selection induces metallodrug susceptibility in an essential chaperonin

Hongzhe Sun, S. Cun, 2010, Proceedings of the National Academy of Sciences.

Bismuth subcarbonate nanoparticles fabricated by water-in-oil microemulsion-assisted hydrothermal process exhibit anti-Helicobacter pylori properties

Hongzhe Sun, C. Che, Jiliang Wu, 2010 .

Controlled synthesis of high crystalline bismuth sulfide nanorods: using bismuth citrate as a precursor

Hongzhe Sun, C. Che, Rong Chen, 2005 .

Iron-containing lipoprotein SiaA in SiaABC, the primary heme transporter of Streptococcus pyogenes

Qing‐Yu He, Hongzhe Sun, R. Ge, 2010, JBIC Journal of Biological Inorganic Chemistry.

Lipoprotein MtsA of MtsABC in Streptococcus pyogenes primarily binds ferrous ion with bicarbonate as a synergistic anion

Qing‐Yu He, Hongzhe Sun, R. Ge, 2008, FEBS letters.

The role of citrate, lactate and transferrin in determining titanium release from surgical devices into human serum

Hongzhe Sun, Lijian Jin, Minji Wang, 2018, JBIC Journal of Biological Inorganic Chemistry.

THE BIOLOGICAL AND MEDICINAL CHEMISTRY OF BISMUTH

P. Sadler, Hongzhe Sun, Hongyan Li, 1997 .

Inhibition of SARS coronavirus helicase by bismuth complexes.

J. Tanner, Hongzhe Sun, Jian-Dong Huang, 2007, Chemical communications.

Binding of bismuth to serum proteins: implication for targets of Bi(III) in blood plasma.

Hongzhe Sun, K. Szeto, 2003, Journal of inorganic biochemistry.

Urease inactivation by an unusual GroES chaperonin

Hongzhe Sun, S. Cun, 2014, Science China Chemistry.

Inactivation of NikR from Helicobacter pylori by a bismuth drug.

Hongzhe Sun, W. Xia, Hongyan Li, 2019, Journal of inorganic biochemistry.

UreE-UreG Complex Facilitates Nickel Transfer and Preactivates GTPase of UreG in Helicobacter pylori*♦

Hongzhe Sun, Hongyan Li, Xinming Yang, 2015, The Journal of Biological Chemistry.

Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver

Hongzhe Sun, Haibo Wang, Runming Wang, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori † †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures, identified proteomes and bioinformatics data. See DOI: 10.1039/c7sc00766c Click here fo

Hongzhe Sun, Z. Chai, Yuchuan Wang, 2017, Chemical science.

Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms

Z. Zuo, Hongzhe Sun, Yuchuan Wang, 2020, iScience.

Gold(III) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells.

Hongzhe Sun, C. Che, R. W. Sun, 2003, Chemical communications.

Thermodynamic and kinetic aspects of metal binding to the histidine-rich protein, Hpn.

Qing‐Yu He, Hongzhe Sun, R. Ge, 2006, Journal of the American Chemical Society.

Fabrication of bismuth subcarbonate nanotube arrays from bismuth citrate.

Hongzhe Sun, C. Che, Rong Chen, 2006, Chemical communications.

Probing of bismuth antiulcer drug targets in H. pylori by laser ablation-inductively coupled plasma mass spectrometry.

Hongzhe Sun, J. Szpunar, R. Lobinski, 2012, Metallomics : integrated biometal science.

"Anion clamp" allows flexible protein to impose coordination geometry on metal ions.

P. Sadler, Hongzhe Sun, Hongmin Zhang, 2015, Chemical communications.

Activation of carboplatin and nedaplatin by the N-terminus of human copper transporter 1 (hCTR1)

Hongzhe Sun, Zijian Guo, Hongyan Li, 2012 .

Metals in Biology and Medicine

Hongzhe Sun, C. Che, Rongde Chen, 2002 .

Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1.

Hongzhe Sun, Hongyan Li, Qiong Liu, 2013, Chemical communications.

Structural, metagenomic and metabolic shifts in multispecies freshwater biofilm models exposed to silver nanoparticles

Haibo Wang, Hongzhe Sun, O. Habimana, 2022, Journal of Environmental Chemical Engineering.

Double-strand DNA cleavage by copper complexes of 2,2'-dipyridyl with guanidinium/ammonium pendants.

Hongzhe Sun, M. Tong, L. Ji, 2008, Dalton transactions.

An ensemble 3D deep-learning model to predict protein metal-binding site

Hongzhe Sun, Lijian Jin, M. Koohi-Moghadam, 2022, Cell Reports Physical Science.

Bismuth in medicine.

Hongzhe Sun, Li Zhang, K. Szeto, 2004, Metal ions in biological systems.

Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1

Yi Lu, Hongzhe Sun, X. Liang, 2009, JBIC Journal of Biological Inorganic Chemistry.

Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters

J. Chan, K. Yuen, Hongzhe Sun, 2020, Nature Microbiology.

Phosphodiester hydrolysis and specific DNA binding and cleavage promoted by guanidinium-functionalized zinc complexes.

Hongzhe Sun, L. Ji, Z. Mao, 2009, Journal of inorganic biochemistry.

Metal-based strategies for the fight against COVID-19.

Hongzhe Sun, Shuofeng Yuan, Hongyan Li, 2022, Chemical communications.

Coordination chemistry of metals in medicine: target sites for bismuth

P. Sadler, Hongzhe Sun, Hongyan Li, 1999 .

Synthesis, structure, and activity of supramolecular mimics for the active site and arg141 residue of copper, zinc-superoxide dismutase.

C. Su, Hongzhe Sun, L. Ji, 2007, Inorganic chemistry.

Rationalisation of metal binding to transferrin: Prediction of metal-protein stability constants

P. Sadler, Hongzhe Sun, Hongyan Li, 1997 .

Silver nanoparticles: partial oxidation and antibacterial activities

P. Tam, Qing‐Yu He, Hongzhe Sun, 2007, JBIC Journal of Biological Inorganic Chemistry.

Binding of oxo-Cu2 clusters to ferric ion-binding protein A from Neisseria gonorrhoeae: a structural insight.

Hongzhe Sun, Hongfei Wang, Weijing Chen, 2013, Metallomics : integrated biometal science.

Bismuth antiulcer complexes

P. Sadler, Hongzhe Sun, 1999 .

Bismuth drugs as antimicrobial agents

Hongzhe Sun, Runming Wang, Hongyan Li, 2020 .

Biocoordination chemistry of bismuth : Recent advances

Hongzhe Sun, N. Yang, 2007 .

Glutathione and multidrug resistance protein transporter mediate a self-propelled disposal of bismuth in human cells

Hongzhe Sun, G. C. Chan, Yau-tsz Lai, 2015, Proceedings of the National Academy of Sciences.

Bismuth-The Magic Element.

M. Kanatzidis, Hongzhe Sun, S. Dehnen, 2020, Inorganic chemistry.

Solid-state carbon-13 nuclear magnetic resonance investigations of bismuth citrate complexes and crystal structure of Na2[Bi2(cit)2]·7H2O

P. Sadler, M. Mcpartlin, I. Scowen, 1996 .

Complexation of ytterbium to human transferrin and its uptake by K562 cells.

Z. Qian, Rong Li, Hongzhe Sun, 2002, European journal of biochemistry.

An oscillating C2(2-) unit inside a copper rectangle.

Hongzhe Sun, V. Yam, F. Maseras, 2003, Chemical communications.

BiOX (X=Cl, Br, I) nanostructures: mannitol-mediated microwave synthesis, visible light photocatalytic performance, and Cr(VI) removal capacity.

Hongzhe Sun, S. Xiao, Runming Wang, 2013, Journal of colloid and interface science.

Tunable BiOCl hierarchical nanostructures for high-efficient photocatalysis under visible light irradiation

Hongzhe Sun, G. Cheng, Runming Wang, 2013 .

Template-free fabrication of Bi2O3 and (BiO)2CO3 nanotubes and their application in water treatment.

Hongzhe Sun, Jiliang Wu, Runming Wang, 2012, Chemistry.

New approach to the solution chemistry of bismuth citrate antiulcer complexes

P. Sadler, Hongzhe Sun, J. Parkinson, 1998 .

Targeting the Thioredoxin Reductase-Thioredoxin System from Staphylococcus aureus by Silver Ions.

Hongzhe Sun, W. Xia, Hongyan Li, 2017, Inorganic chemistry.

Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin

Yang Wang, Yi Wang, Hongzhe Sun, 2021, Chemical science.

Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance

Zeling Xu, A. Yan, Hongzhe Sun, 2021, Nature Communications.

In Vitro Inhibition of Human Immunodeficiency Virus Type‐1 (HIV‐1) Reverse Transcriptase by Gold(III) Porphyrins

Hongzhe Sun, C. Che, R. W. Sun, 2004, Chembiochem : a European journal of chemical biology.

Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles.

Hongzhe Sun, P. Andrews, Hongyan Li, 2021, Chemical Society reviews.

Identification of Proteins Related to Nickel Homeostasis in Helicobater pylori by Immobilized Metal Affinity Chromatography and Two-Dimensional Gel Electrophoresis

Qing‐Yu He, Hongzhe Sun, R. Ge, 2007, Metal-based drugs.

Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori.

Qing‐Yu He, J. Tanner, Hongzhe Sun, 2006, The Biochemical journal.

Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria

A. Yan, Hongzhe Sun, Hongyan Li, 2023, JBIC Journal of Biological Inorganic Chemistry.

Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

Ronald A. Li, S. Chanda, R. Sun, 2021, Nature.

Recent advances in bioinorganic chemistry of bismuth

Hongzhe Sun, Hongyan Li, 2012, Current Opinion in Chemical Biology.

Large-scale synthesis of bismuth hollow nanospheres for highly efficient Cr(VI) removal.

Hongzhe Sun, F. Qin, Guangfang Li, 2012, Dalton transactions.

Bismuth: Environmental Pollution and Health Effects☆

Hongzhe Sun, Runming Wang, Hongyan Li, 2019, Encyclopedia of Environmental Health.

Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors

Hongzhe Sun, R. Kao, Runming Wang, 2018, Nature Communications.

Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

Hongzhe Sun, P. Woo, Runming Wang, 2018, PLoS biology.

Functional disruption of HypB, a GTPase of Helicobacter pylori, by bismuth.

Hongzhe Sun, W. Xia, Hongyan Li, 2014, Chemical communications.

Dopamine-assisted immobilization of peptide arginine–glycine–aspartic acid to enhance the cellular performances of MC3T3-E1 cells of carbon–carbon composites

Hongzhe Sun, X. Liao, Qianqian Wu, 2019, Journal of biomaterials applications.

Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway

Hongzhe Sun, Z. Qian, Hongzhe Sun, 2002, Pharmacological Reviews.

Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures and omics data. See DOI: 10.1039/c8sc01668b

Hongzhe Sun, Yulan Wang, Yuchuan Wang, 2018, Chemical science.

Interactions of Bismuth Complexes with Metallothionein(II)*

P. Sadler, Hongzhe Sun, Hongyan Li, 1999, The Journal of Biological Chemistry.

Metalloproteomics in conjunction with other omics for uncovering the mechanism of action of metallodrugs: Mechanism-driven new therapy development.

Ying Zhou, Hongyan Li, Haibo Wang, 2020, Current opinion in chemical biology.

Metalloproteomic Approaches for Matching Metals to Proteins: The Power of Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Hongzhe Sun, Haibo Wang, Hongyan Li, 2020, Chemistry Letters.

Application of Metallomics and Metalloproteomics for Understanding the Molecular Mechanisms of Action of Metal-Based Drugs

Hongzhe Sun, Yuchuan Wang, Haibo Wang, 2017 .

Identification and characterization of metallodrug binding proteins by (metallo)proteomics

Hongzhe Sun, Xuesong Sun, C. Tsang, 2009 .

Structure of colloidal bismuth subcitrate (CBS) in dilute HCl: unique assembly of bismuth citrate dinuclear units ([Bi(cit)(2)Bi](2-)).

W. Li, Hongzhe Sun, N. Zhu, 2003, Journal of the American Chemical Society.

Determination of Bismuth in Serum Urine by Direct Injection Nebulization Inductively Coupled Plasma Mass Spectrometry

P. Sadler, Hongzhe Sun, Hongyan Li, 1997 .

Competitive Binding of Bismuth to Transferrin and Albumin in Aqueous Solution and in Blood Plasma*

P. Sadler, A. Mason, R. Woodworth, 2001, The Journal of Biological Chemistry.

Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli

Zeling Xu, A. Yan, Hongzhe Sun, 2019, The Journal of Biological Chemistry.

Biological Chemistry of Antimony and Bismuth

Hongzhe Sun, N. Yang, 2010 .

Synthetic Peptides outside the Spike Protein Heptad Repeat Regions as Potent Inhibitors of Sars-Associated Coronavirus

Y. Guan, Honglin Chen, K. Yuen, 2005, Antiviral therapy.

Reduction of pentavalent antimony by trypanothione and formation of a binary and ternary complex of antimony(III) and trypanothione

Hongzhe Sun, Fei Li, Siucheong Yan, 2003, JBIC Journal of Biological Inorganic Chemistry.

Structure of a nickel chaperone, HypA, from Helicobacter pylori reveals two distinct metal binding sites.

Hongzhe Sun, W. Xia, K. Sze, 2009, Journal of the American Chemical Society.

Loss of APD1 in Yeast Confers Hydroxyurea Sensitivity Suppressed by Yap1p Transcription Factor

Hongzhe Sun, Kam-Leung Siu, D. Jin, 2015, Scientific Reports.

Title Loss of APD 1 in Yeast Confers Hydroxyurea SensitivitySuppressed by Yap 1 p Transcription Factor

Hongzhe Sun, Kam-Leung Siu, H. V. Tang, 2015 .

Solution structures, dynamics, and lipid‐binding of the sterile α‐motif domain of the deleted in liver cancer 2

I. Ng, Hongzhe Sun, K. Fung, 2007, Proteins.

Bismuth drugs tackle Porphyromonas gingivalis and attune cytokine response in human cells.

Hongzhe Sun, Hongyan Li, Lijian Jin, 2019, Metallomics : integrated biometal science.

Immobilized Metal Affinity Chromatography (IMAC) for Metalloproteomics and Phosphoproteomics

Hongzhe Sun, Hongyan Li, Yy Chang, 2017 .

Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation

Hongzhe Sun, W. Xia, Hongyan Li, 2011, JBIC Journal of Biological Inorganic Chemistry.

Binding of ruthenium and osmium at non‑iron sites of transferrin accounts for their iron-independent cellular uptake.

Hongzhe Sun, Q. Hao, Haibo Wang, 2022, Journal of inorganic biochemistry.

Tracking iron-associated proteomes in pathogens by a fluorescence approach.

Hongzhe Sun, Hongyan Li, Lijian Jin, 2017, Metallomics : integrated biometal science.

Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe

Quan Hao, Hongzhe Sun, Hongzhe Sun, 2012, Scientific Reports.

Metalloproteomics of Arsenic, Antimony and Bismuth Based Drugs

Hongzhe Sun, R. Ge, C. Tsang, 2010 .

Structure of RPA32 bound to the N‐terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins

Hongzhe Sun, J. Jakoncic, C. Qian, 2014, The FEBS journal.

Novel Neural Network Approach to Predict Drug-Target Interactions Based on Drug Side Effects and Genome-Wide Association Studies

Junwen Wang, Jean-Pierre A. Kocher, Mohamad Koohi-Moghadam, 2018, Human Heredity.

Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli

Zeling Xu, A. Yan, Hongzhe Sun, 2019, PLoS biology.

Title Membrane-inserted conformation of transmembrane domain 4 ofdivalent-metal transporter

Z. Qian, Hongzhe Sun, Li-hua Fei, 2013 .

Membrane-inserted conformation of transmembrane domain 4 of divalent-metal transporter.

Z. Qian, Hongzhe Sun, Fei Li, 2003, The Biochemical journal.

Assembly of Preactivation Complex for Urease Maturation in Helicobacter pylori

Yu Wai Chen, Hongzhe Sun, C. Chuck, 2011, The Journal of Biological Chemistry.

Identification of metal-associated proteins in cells by using continuous-flow gel electrophoresis and inductively coupled plasma mass spectrometry.

G. Jiang, Hongzhe Sun, Yuchuan Wang, 2013, Angewandte Chemie.

Hyperthermia Selectively Destabilizes Oncogenic Fusion Proteins.

S. Chiou, Chih-Hung Hsu, Hongzhe Sun, 2021, Cancer discovery.

Metallomics in Multidisciplinary Research and the Analytical Advances

Hongzhe Sun, Yu-feng Li, 2021, Atomic Spectroscopy.

Title A zinc-binding site by negative selection induces metallodrugsusceptibility in an essential chaperonin

Hongzhe Sun, 2013 .

Eradication of Porphyromonas gingivalis Persisters Through Colloidal Bismuth Subcitrate Synergistically Combined With Metronidazole

Hongzhe Sun, Xuan Li, Lijian Jin, 2021, Frontiers in Microbiology.

Rapid labeling of intracellular His-tagged proteins in living cells

J. Tanner, Hongzhe Sun, M. Chye, 2015, Proceedings of the National Academy of Sciences.

Title Iron and bismuth bound human serum transferrin reveals apartially-opened conformation in the N-lobe

Hongzhe Sun, Q. Hao, Hongmin Zhang, 2012 .

The low pK a value of iron‐binding ligand Tyr188 and its implication in iron release and anion binding of human transferrin

A. Mason, R. Woodworth, Qing‐Yu He, 2004, FEBS letters.

The role of the transferrin-transferrin-receptor system in drug delivery and targeting.

Z. Qian, Hongzhe Sun, Hongyan Li, 2002, Trends in pharmacological sciences.

Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence.

Hongzhe Sun, Panwen Wang, Junwen Wang, 2013, Metallomics : integrated biometal science.

Flavonoid Dimers as Bivalent Modulators for Pentamidine and Sodium Stiboglucanate Resistance in Leishmania

L. Chow, Hongzhe Sun, T. Chan, 2006, Antimicrobial Agents and Chemotherapy.

Transferrin-mediated gold nanoparticle cellular uptake.

Hongzhe Sun, Qing-Yu He, Qing‐Yu He, 2005, Bioconjugate chemistry.

Bismuth-Induced Inactivation of Ferric Uptake Regulator from Helicobacter pylori.

Hongzhe Sun, W. Xia, Hongyan Li, 2017, Inorganic chemistry.

Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin

A. Yan, Hongzhe Sun, R. Kao, 2020, Nature Communications.

Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli

A. Yan, Hongzhe Sun, Q. Hao, 2019 .

Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02032b

A. Yan, Hongzhe Sun, Q. Hao, 2019, Chemical science.

Identification of catabolite control protein A from Staphylococcus aureus as a target of silver ions† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures and tables. See DOI: 10.1039/c7sc02251d

Hongzhe Sun, R. Kao, Runming Wang, 2017, Chemical science.

Inhibition of alcohol dehydrogenase by bismuth☆

Hongzhe Sun, W. Du, Li Zhang, 2004, Journal of Inorganic Biochemistry.

Polymeric architectures of bismuth citrate based on dimeric building blocks

Lihong Hu, Guanhua Chen, Hongzhe Sun, 2010, Science China. Chemistry.

A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori

Qing‐Yu He, J. Tanner, B. Wong, 2007, JBIC Journal of Biological Inorganic Chemistry.

NMR structures and orientation of the fourth transmembrane domain of the rat divalent metal transporter (DMT1) with G185D mutation in SDS micelles

Hongzhe Sun, Fei Li, Hongyan Li, 2005, Biopolymers.

The effect of nitric oxide on metal release from metallothionein-3: gradual unfolding of the protein

Hongzhe Sun, Z. Huang, Hongyan Li, 2008, JBIC Journal of Biological Inorganic Chemistry.

A Histidine-rich and Cysteine-rich Metal-binding Domain at the C Terminus of Heat Shock Protein A from Helicobacter pylori

Marie C. M. Lin, Hongzhe Sun, R. Ge, 2008, Journal of Biological Chemistry.

Chapter 9:Nuclear-based Metallomics in Metal-based Drugs

Hongzhe Sun, R. Ge, I. Chu, 2010 .

Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like

Hongzhe Sun, Hongyan Li, Dong-Mei Zhang, 2008, JBIC Journal of Biological Inorganic Chemistry.

Inhibition of urease by bismuth(III): Implications for the mechanism of action of bismuth drugs

R. Hausinger, Hongzhe Sun, B. Ko, 2006, Biometals.

Bismuth(III) Complexes of the Tripeptide Glutathione (γ‐L‐Glu–L‐Cys–Gly)

P. Sadler, Hongzhe Sun, Hongyan Li, 1996 .

Predicting disease-associated mutation of metal-binding sites in proteins using a deep learning approach

Yuchuan Wang, Mohamad Koohi-Moghadam, Hongyan Li, 2019, Nature Machine Intelligence.

Structure, topology and assembly of a 32-mer peptide corresponding to the loop 3 and transmembrane domain 4 of divalent metal transporter (DMT1) in membrane-mimetic environments.

Hongzhe Sun, Hongyan Li, J. Gu, 2008, Journal of inorganic biochemistry.

A hydroxide lock for metallo-β-lactamases

Hongzhe Sun, Hongyan Li, 2022, Nature Chemistry.

Coordination of Zn2+ (and Cd2+) by Prokaryotic Metallothionein

P. Sadler, Hongzhe Sun, N. Robinson, 1998, The Journal of Biological Chemistry.

Plasmonic metal nanoparticles as efficient mass tags for ion signal amplification and ultrasensitive detection of protein markers.

Hongzhe Sun, C. Lok, Yu-Hong Cheng, 2019, Analytica chimica acta.

Size-tunable fabrication of multifunctional Bi2O3 porous nanospheres for photocatalysis, bacteria inactivation and template-synthesis.

Hongzhe Sun, Yunlin Liu, Runming Wang, 2014, Nanoscale.

Template‐Free Fabrication of Bi2O3 and (BiO)2CO3 Nanotubes and Their Application in Water Treatment.

Hongzhe Sun, Jiliang Wu, Runming Wang, 2013 .

Additive Manufactured Graphene Coating with Synergistic Photothermal and Superhydrophobic Effects for Bactericidal Applications

Ching-Yuen Chan, Hongzhe Sun, Guijun Li, 2019, Global challenges.

Cytotoxicity of arsenic trioxide in single leukemia cells by time-resolved ICP-MS together with lanthanide tags.

Hongzhe Sun, Hongyan Li, Ying Zhou, 2017, Chemical communications.

Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress

Hongzhe Sun, A. Xu, Guibin Jiang, 2023, Nature Communications.

Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation

Hongzhe Sun, Huinan Li, Z. Mao, 2022, The Journal of biological chemistry.

Structure-oriented bioinformatic approach exploring histidine-rich clusters in proteins.

Hongzhe Sun, Yuen-Yan Chang, S. Cun, 2013, Metallomics : integrated biometal science.

[1H,13C] NMR determination of the order of lobe loading of human transferrin with iron: comparison with other metal ions

P. Sadler, A. Mason, R. Woodworth, 1998, FEBS letters.

The unique trimeric assembly of the virulence factor HtrA from Helicobacter pylori occurs via N-terminal domain swapping

Hongzhe Sun, Peng Zheng, W. Xia, 2019, The Journal of Biological Chemistry.

Tracking bismuth antiulcer drug uptake in single Helicobacter pylori cells.

Hongzhe Sun, Koon-sing Ho, W. Chan, 2011, Journal of the American Chemical Society.

Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography.

Hongzhe Sun, Yuchuan Wang, Hongyan Li, 2015, Chemical communications.

Systems Approaches for Unveiling the Mechanism of Action of Bismuth Drugs: New Medicinal Applications beyond Helicobacter Pylori Infection.

Hongzhe Sun, Runming Wang, Hongyan Li, 2018, Accounts of chemical research.

Metallomics in environmental and health related research: Current status and perspectives

G. Jiang, Hongzhe Sun, Yuchuan Wang, 2013 .

Dynamic and Temporal Transcriptomic Analysis Reveals Ferroptosis-Mediated Antileukemia Activity of S-Dimethylarsino-Glutathione: Insights into Novel Therapeutic Strategy

Hongzhe Sun, Haibo Wang, Hongyan Li, 2021 .

A Ni-NTA-based red fluorescence probe for protein labelling in live cells.

Hongzhe Sun, Hongyan Li, Ya Yang, 2017, Journal of materials chemistry. B.

Histidine-rich protein Hpn from Helicobacter pylori forms amyloid-like fibrils in vitro and inhibits the proliferation of gastric epithelial AGS cells.

Hongzhe Sun, R. Ge, Xuesong Sun, 2011, Biochimica et biophysica acta.

Solution structure and dynamics of human metallothionein‐3 (MT‐3)

Hongzhe Sun, Z. Huang, K. Sze, 2006, FEBS letters.

Nickel translocation between metallochaperones HypA and UreE in Helicobacter pylori.

Hongzhe Sun, W. Xia, Hongyan Li, 2014, Metallomics : integrated biometal science.

Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes.

H. Baker, E. Baker, Qing‐Yu He, 2009, Biochemistry.

S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3.3, leading to TRAIL-induced apoptosis in leukemia cells.

Hongzhe Sun, Haibo Wang, Hongyan Li, 2019, Chemical communications.

Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase

Hongzhe Sun, Z. Mao, W. Xia, 2020 .

Functional disruption of peroxiredoxin by bismuth antiulcer drugs attenuates Helicobacter pylori survival

Hongzhe Sun, Hongyan Li, Lijian Jin, 2017, JBIC Journal of Biological Inorganic Chemistry.

Stereo- and enantioselective alkene epoxidations: a comparative study of D4- and D2-symmetric homochiral trans-dioxoruthenium(VI) porphyrins.

Hongzhe Sun, C. Che, Wing-Yiu Yu, 2002, Chemistry.

Computed Tomography of Cartilage: An Exploration of Novel Cationic Bismuth Contrast Agent

Hongzhe Sun, V. Vardhanabhuti, A. Bhattarai, 2022, Annals of Biomedical Engineering.

A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein

Hongzhe Sun, K. Man, G. C. Chan, 2019, Translational oncology.

Multiplex Single‐Cell Analysis of Cancer Cells Enables Unbiased Uncovering Subsets Associated with Cancer Relapse: Heterogeneity of Multidrug Resistance in Precursor B‐ALL

E. Cheung, Hongzhe Sun, Hongyan Li, 2021, ChemMedChem.

Facile Microwave Synthesis of 3D Flowerlike BiOBr Nanostructures and Their Excellent CrVI Removal Capacity

Hongzhe Sun, F. Qin, Guangfang Li, 2012 .

Comparison between copper and cisplatin transport mediated by human copper transporter 1 (hCTR1).

Hongzhe Sun, Hongyan Li, Xinghao Wang, 2012, Metallomics : integrated biometal science.

Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments.

Z. Qian, Hongzhe Sun, Fei Li, 2004, European journal of biochemistry.

Integration of fluorescence imaging with proteomics enables visualization and identification of metallo-proteomes in living cells.

Hongzhe Sun, Yuchuan Wang, Hongyan Li, 2017, Metallomics : integrated biometal science.

Metallo-GTPase HypB from Helicobacter pylori and Its Interaction with Nickel Chaperone Protein HypA*

Hongzhe Sun, W. Xia, Hongyan Li, 2011, The Journal of Biological Chemistry.

Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors

Hongzhe Sun, R. Kao, Runming Wang, 2018, Nature Communications.

A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein

Hongzhe Sun, K. Man, G. C. Chan, 2019, Translational oncology.

Hongzhe Sun, Yuchuan Wang, Bingjie Han, 2019, Chemical science.

Ti(IV) uptake and release by human serum transferrin and recognition of Ti(IV)-transferrin by cancer cells: understanding the mechanism of action of the anticancer drug titanocene dichloride.

P. Sadler, P. Sadler, Hongzhe Sun, 2000, Biochemistry.

Orally administered bismuth drug together with N-acetyl cysteine as a broad-spectrum anti-coronavirus cocktail therapy

J. Chan, K. Yuen, Z. Zuo, 2021, Chemical science.

Recognition of Proteins by Metal Chelation-Based Fluorescent Probes in Cells

Hongzhe Sun, Hongyan Li, N. Jiang, 2019, Front. Chem..

Metalloproteomics for Biomedical Research: Methodology and Applications.

Hongzhe Sun, Hongyan Li, Ying Zhou, 2022, Annual review of biochemistry.

Interaction of antimony tartrate with the tripeptide glutathione implication for its mode of action.

Hongzhe Sun, S. C. Yan, Siucheong Yan, 2000, European journal of biochemistry.

Covalently linking the Escherichia coli global anaerobic regulator FNR in tandem allows it to function as an oxygen stable dimer.

A. Yan, Jun Liu, Hongzhe Sun, 2012, Biochemical and Biophysical Research Communications - BBRC.

NMR studies of metalloproteins.

Hongzhe Sun, Hongyan Li, 2012, Topics in current chemistry.

Large-scale synthesis of bismuth hollow nanospheres for highly efficient Cr(VI) removal.

Hongzhe Sun, F. Qin, Guangfang Li, 2012, Dalton transactions.

Microwave synthesis of BiPO4 nanostructures and their morphology-dependent photocatalytic performances.

Hongzhe Sun, Guangfang Li, Rong Chen, 2011, Journal of colloid and interface science.

Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

Hongzhe Sun, P. Woo, Runming Wang, 2018, PLoS biology.

Multifaceted SlyD from Helicobacter pylori: implication in [NiFe] hydrogenase maturation

Hongzhe Sun, W. Xia, Hongyan Li, 2011, JBIC Journal of Biological Inorganic Chemistry.

UreE-UreG Complex Facilitates Nickel Transfer and Preactivates GTPase of UreG in Helicobacter pylori*♦

Hongzhe Sun, Hongyan Li, Xinming Yang, 2015, The Journal of Biological Chemistry.

Nickel translocation between metallochaperones HypA and UreE in Helicobacter pylori.

Hongzhe Sun, W. Xia, Hongyan Li, 2014, Metallomics : integrated biometal science.

Identification of metal-associated proteins in cells by using continuous-flow gel electrophoresis and inductively coupled plasma mass spectrometry.

G. Jiang, Hongzhe Sun, Yuchuan Wang, 2013, Angewandte Chemie.

Green Fluorescent Probe for Imaging His6-Tagged Proteins Inside Living Cells.

Hongzhe Sun, Hongyan Li, Yuen-Yan Chang, 2019, ACS sensors.

Inhibition of SARS coronavirus helicase by bismuth complexes.

J. Tanner, Hongzhe Sun, Jian-Dong Huang, 2007, Chemical Communications.

Flavonoid Dimers as Bivalent Modulators for Pentamidine and Sodium Stiboglucanate Resistance in Leishmania

L. Chow, Hongzhe Sun, T. Chan, 2006, Antimicrobial Agents and Chemotherapy.

Complexation of Antimony(III) by Trypanothione.

Hongzhe Sun, Siucheong Yan, K. Ding, 2000, Angewandte Chemie.