V. Stella

V. Stella, A. Lopalco, W. Thompson, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Methylprednisolone esters of hyaluronic acid in ophthalmic drug delivery: in vitro and in vivo release studies

A. Urtti, E. Topp, V. Stella, 1992 .

Kinetics and Mechanism of Isomerization of Cyclosporin A

R. Oliyai, V. Stella, 1992, Pharmaceutical Research.

Kinetics and mechanism of ionization of the carbon acids 4'-substituted 2-phenyl-1,3-indandiones.

V. Stella, R. Gish, 1979, Journal of pharmaceutical sciences.

Effects of short-term dietary exposure to polychlorinated biphenyls on pharmacokinetics of intravenous pentobarbital in rats.

V. Stella, C. Chu, 1980, Journal of pharmaceutical sciences.

Effects of long-term exposure to environmental levels of polychlorinated biphenyls on pharmacokinetics of pentobarbital in rats.

V. Stella, J. Bruckner, W. Jiang, 1977, Journal of pharmaceutical sciences.

Boric Acid, a Lewis Acid with Unique and Unusual Properties: Formulation Implications.

V. Stella, N. Denora, V. Laquintana, 2020, Journal of pharmaceutical sciences.

Pharmacokinetics of Drug Targeting: Specific Implications for Targeting via Prodrugs

V. Stella, A. Kearney, 1991 .

Stability, compatibility, and plasticizer extraction of taxol (NSC-125973) injection diluted in infusion solutions and stored in various containers.

V. Stella, L. Trissel, W. Waugh, 1991, American journal of hospital pharmacy.

Comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies to target a model immunomodulator to the lymphatic system

V. Stella, C. Porter, W. Charman, 2013 .

Kinetics and mechanism of degradation of epothilone-D: an experimental anticancer agent.

V. Stella, S. Silchenko, M. Jumaa, 2004, Journal of pharmaceutical sciences.

Diffusion of macromolecules in membranes of hyalyronic acid esters

E. Topp, V. Stella, D. Papini, 1993 .

Microspheres of hyaluronic acid esters—Fabrication methods and in vitro hydrocortisone release

E. Topp, V. Stella, L. Benedetti, 1990 .

The determination of the amphiphilic properties of a prodrug (DDMS) of phenytoin in aqueous media

A. P. Lötter, V. Stella, D. G. Müller, 1992 .

Tautomerism of phenindione, 2-phenyl-1,3-indandione, in dipolar aprotic/hydrocarbon solvent mixtures

V. Stella, J. Pipkin, 1982 .

Factors affecting the deamidation of vancomycin in aqueous solutions

V. Stella, A. Antipas, D. Velde, 1994 .

Phosphoryloxymethyl Carbamates and Carbonates—Novel Water-Soluble Prodrugs for Amines and Hindered Alcohols

R. Oliyai, M. Safadi, V. Stella, 1993, Pharmaceutical Research.

Comparative Effects of (SBE)7m‐β‐CD and HP‐β‐CD on the Stability of Two Anti‐neoplastic Agents, Melphalan and Carmustine

V. Stella, R. Rajewski, D. Velde, 2000 .

Sulfoalkyl ether-alkyl ether cyclodextrin derivatives, their synthesis, NMR characterization, and binding of 6alpha-methylprednisolone.

V. Stella, T. Ozeki, D. Velde, 2005, Journal of pharmaceutical sciences.

Phenytoin prodrugs IV: Hydrolysis of various 3-(hydroxymethyl)phenytoin esters.

S. Varia, V. Stella, S. Schuller, 1984, Journal of pharmaceutical sciences.

Evaluation of mucoadhesive properties of hyaluronic acid benzyl esters

E. Topp, V. Stella, L. Benedetti, 1994 .

Binding constants for aromatic amino acids and their derivatives with sulfobutyl ether β-cyclodextrin determined using capillary electrophoresis

V. Stella, T. Ozeki, M. Miyajima, 2004 .

Degradation of paclitaxel and related compounds in aqueous solutions II: Nonepimerization degradation under neutral to basic pH conditions.

V. Stella, Jiaher Tian, 2008, Journal of pharmaceutical sciences.

Characterization of prednisolone in controlled porosity osmotic pump pellets using solid-state NMR spectroscopy.

J. Lubach, E. Munson, V. Stella, 2007, Journal of pharmaceutical sciences.

Phenytoin prodrugs III: water-soluble prodrugs for oral and/or parenteral use.

S. Varia, V. Stella, K. Sloan, 1984, Journal of pharmaceutical sciences.

Some Preformulation Studies of Pyruvic Acid and Other α-Keto Carboxylic Acids in Aqueous Solution: Pharmaceutical Formulation Implications for These Peroxide Scavengers.

V. Stella, J. Douglas, N. Denora, 2019, Journal of pharmaceutical sciences.

Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide.

R. Schowen, V. Stella, J. Douglas, 2016, Journal of pharmaceutical sciences.

Prodrugs of phosphates, phosphonates, and phosphinates

V. Stella, J. Krise, 1996 .

Preliminary safety evaluation of parenterally administered sulfoalkyl ether beta-cyclodextrin derivatives.

V. Stella, J. Bresnahan, R. Rajewski, 1995, Journal of pharmaceutical sciences.

Application of benzyl hyaluronate membranes as potential wound dressings: evaluation of water vapour and gas permeabilities.

E. Topp, V. Stella, L. Benedetti, 1996, Biomaterials.

Prodrugs and Parenteral Drug Delivery

V. Stella, J. Hemenway, 2007 .

A Mechanistic and Kinetic Study of the E-Ring Hydrolysis and Lactonization of a Novel Phosphoryloxymethyl Prodrug of Camptothecin

R. Schowen, V. Stella, Bradley A. Hanson, 2003, Pharmaceutical Research.

Hydrolysis of the quinone methide of butylated hydroxytoluene in aqueous solutions.

V. Stella, M. Toteva, M. Willcockson, 2013, Journal of pharmaceutical sciences.

In vitro and in vivo evaluation of a novel water-soluble N-glycyl prodrug (N-GLY-CBZ) of carbamazepine.

V. Stella, J. Hemenway, 2010, Journal of Pharmacy and Science.

Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.

V. Stella, G. Georg, D. VanderVelde, 2010, Journal of pharmaceutical sciences.

A novel prodrug strategy for beta-dicarbonyl carbon acids: syntheses and evaluation of the physicochemical characteristics of C-phosphoryloxymethyl (POM) and phosphoryloxymethyloxymethyl (POMOM) prodrug derivatives.

V. Stella, S. Dhareshwar, 2010, Journal of pharmaceutical sciences.

Mechanism of hydrolysis and structure-stability relationship of enaminones as potential prodrugs of model primary amines.

V. Stella, V. Naringrekar, 1990, Journal of pharmaceutical sciences.

Prodrug strategies to overcome poor water solubility.

V. Stella, Valentino J Stella, Kwame W Nti-Addae, 2007, Advanced drug delivery reviews.

Amino acid derivatives of dapsone as water-soluble prodrugs

V. Stella, W. Charman, N. Pochopin, 1995 .

Pharmacokinetics of dapsone and amino acid prodrugs of dapsone.

V. Stella, W. Charman, N. Pochopin, 1994, Drug metabolism and disposition: the biological fate of chemicals.

Kinetics of rearrangement and hydrolysis of amino acid derivatives of prazosin

V. Stella, W. Charman, N. Pochopin, 1994 .

Photostability of 2-hydroxymethyl-4,8-dibenzo[1,2-b:5,4-b']dithiophene-4,8-dione (NSC 656240), a potential anticancer drug.

V. Stella, S. Silchenko, C. Schöneich, 2003, International journal of pharmaceutics.

Sulfenamides as prodrugs of NH-acidic compounds: a new prodrug option for the amide bond.

V. Stella, V. Karunaratne, Victor R. Guarino, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity.

M. R. Mejillano, R. Himes, V. Stella, 1992, Journal of medicinal chemistry.

Kinetics of Synthesis of d4-Succinic Anhydride from Succinic Anhydride and d1-Acetic Acid

V. Stella, 1973 .

SYNTHESIS OF A NOVEL ESTERASE-SENSITIVE CYCLIC PRODRUG OF A HEXAPEPTIDE USING AN (ACYLOXY)ALKOXY PROMOIETY

R. Borchardt, V. Stella, G. Pauletti, 1997 .

Hydrolytic behavior of N-acyl phthalimides.

V. Stella, T. Higuchi, 1973, Journal of pharmaceutical sciences.

Isolation and characterization by NMR spectroscopy of three monosubstituted 4-sulfobutyl ether derivatives of cyclomaltoheptaose (β-cyclodextrin)

V. Stella, R. Tait, R. Rajewski, 1997 .

Breakdown kinetics of C-hydroxymethyl beta-dicarbonyl derivatives of carbon acids: implications in the bioconversion rate of C-phosphoryloxymethyl prodrugs of carbon acids.

V. Stella, S. Dhareshwar, 2009, Journal of pharmaceutical sciences.

Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists

Valentino J. Stella, Gordon L. Amidon, K. A. Connors, 1979 .

Characterization of sulphoalkyl ether derivatives of beta-cyclodextrin by capillary electrophoresis with indirect UV detection.

V. Stella, D. Skanchy, R. Tait, 1992, Journal of pharmaceutical and biomedical analysis.

Effect of Cyclodextrin Charge on Complexation of Neutral and Charged Substrates: Comparison of (SBE)7M-β-CD to HP-β-CD

V. Stella, R. Rajewski, V. J. Stella, 2001, Pharmaceutical Research.

Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery.

V. Stella, R. Rajewski, R A Rajewski, 1996, Journal of pharmaceutical sciences.

Sulfobutyl Ether .beta.-Cyclodextrin as a Chiral Discriminator for Use with Capillary Electrophoresis

V. Stella, R. Tait, J. Stobaugh, 1994 .

Evaluation of the utility of capillary electrophoresis for the analysis of sulfobutyl ether beta-cyclodextrin mixtures.

V. Stella, R. Tait, R. Rajewski, 1996, Journal of pharmaceutical and biomedical analysis.

Acylation of phenol by cyclic and acyclic anhydrides in anhydrous acetic acid.

M. Haddadin, V. Stella, T. Higuchi, 1975, Journal of pharmaceutical sciences.

Thermodynamics of Binding of Neutral Molecules to Sulfobutyl Ether β-Cyclodextrins (SBE-β-CDs): The Effect of Total Degree of Substitution

V. Stella, R. Rajewski, V. Zia, 2000, Pharmaceutical Research.

Thermodynamics of binding of neutral molecules to sulfobutyl ether beta-cyclodextrins (SBE-beta-CDs): the effect of total degree of substitution.

V. Stella, R. Rajewski, V. Zia, 2000, Pharmaceutical research.

Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultured endothelial cells (HUV-EC).

K. Audus, V. Stella, N. Medlicott, 1998, Journal of pharmaceutical sciences.

Effect of SBE4-β-CD, a sulfobutyl ether β-cyclodextrin, on the stability and solubility of O6-benzylguanine (NSC-637037) in aqueous solutions

D. Bindra, V. Stella, B. Górecka, 1995 .

Design and Evaluation of an Osmotic Pump Tablet (OPT) for Chlorpromazine Using (SBE)7m-β-CD

V. Stella, K. Uekama, T. Irie, 1999, Pharmaceutical Research.

Sulfobutyl ether β-cyclodextrin (SBE-β-CD) in eyedrops improves the tolerability of a topically applied pilocarpine prodrug in rabbits

A. Urtti, V. Stella, K. Järvinen, 1995 .

Sulfobutylether-β-cyclodextrin

V. Stella, R. Rajewski, 2020, International Journal of Pharmaceutics.

Sulfobutyl ether beta-cyclodextrin (SBE-beta-CD) in eyedrops improves the tolerability of a topically applied pilocarpine prodrug in rabbits.

A. Urtti, V. Stella, T. Järvinen, 1995, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

The effect of a modified beta-cyclodextrin, SBE4-beta-CD, on the aqueous stability and ocular absorption of pilocarpine.

V. Stella, K. Järvinen, T. Järvinen, 1994, Current eye research.

Kinetics of hydrolysis of fetindomide (NSC-373965), bis-N,N′-phenylalanyloxymethyl prodrug of mitindomide (NSC-284356); an unexpected catalytic effect of generated formaldehyde

V. Stella, C. Riley, F. Sendo, 1988 .

Phenindione solubility in mixed organic solvents: analysis of the role of specific hydrogen and non-hydrogen bonding interactions

V. Stella, J. Pipkin, 1983 .

Effect of cyclodextrin charge on complexation of neutral and charged substrates: comparison of (SBE)7M-beta-CD to HP-beta-CD.

V. Stella, R. Rajewski, V Zia, 2001, Pharmaceutical research.

New injectable melphalan formulations utilizing (SBE)7m-β-CD or HP-β-CD

V. Stella, R. Rajewski, D. Q. Ma, 1999 .

Increased shelf-life of fosphenytoin: solubilization of a degradant, phenytoin, through complexation with (SBE)7m-beta-CD.

V. Stella, S. Narisawa, 1998, Journal of pharmaceutical sciences.

When can cyclodextrins be considered for solubilization purposes?

V. Stella, Valentino J Stella, Venkatramana M Rao, 2003, Journal of pharmaceutical sciences.

Ocular sustained delivery of prednisolone using hyaluronic acid benzyl ester films

E. Topp, V. Stella, L. Benedetti, 1994 .

Preformulation solubility and kinetic studies of 2',3'-dideoxypurine nucleosides: potential anti-AIDS agents

V. Stella, B. D. Anderson, M. Wygant, 1988 .

β‐Cyclodextrin Derivatives, SBE4‐β‐CD and HP–β‐CD, Increase the Oral Bioavailability of Cinnarizine in Beagle Dogs

Valentino J. Stella, Tomi Järvinen, V. Stella, 1995 .

Proton inventory of phthalic anhydride hydrolysis. Comments on analysis of proton-inventory data

R. Schowen, V. Stella, M. Coyne, 1980 .

Mechanism of degradation of the investigational cytotoxic agent, cyclodisone (NSC-348948)

V. Stella, K. Umprayn, W. Waugh, 1990 .

Phase solubility and structure of the inclusion complexes of prednisolone and 6 alpha-methyl prednisolone with various cyclodextrins.

V. Stella, F. Aachmann, R. Wimmer, 2005, Journal of pharmaceutical sciences.

Dissolution and ionization of warfarin.

V. Stella, J. Pipkin, K. G. Mooney, 1984, Journal of pharmaceutical sciences.

Halohydrin analogues of cryptophycin 1: synthesis and biological activity.

R. Himes, V. Stella, G. Georg, 1998, Bioorganic & medicinal chemistry letters.

Chemical Drug Stability in Lipids, Modified Lipids, and Polyethylene Oxide-Containing Formulations

V. Stella, 2013, Pharmaceutical Research.

Prodrugs of Alcohols and Phenols

V. Stella, S. Dhareshwar, 2007 .

Gellan-based systems for ophthalmic sustained delivery of methylprednisolone

E. Topp, V. Stella, L. Callegaro, 1993 .

A novel prodrug approach for tertiary amines. 3. In vivo evaluation of two N-phosphonooxymethyl prodrugs in rats and dogs.

V. Stella, S. Charman, W. Charman, 1999, Journal of pharmaceutical sciences.

A Case for Prodrugs

V. Stella, 2007 .

Prodrug Strategies for Improving Drug-Like Properties

V. Stella, 2006 .

Controlled and complete release of a model poorly water-soluble drug, prednisolone, from hydroxypropyl methylcellulose matrix tablets using (SBE)(7m)-beta-cyclodextrin as a solubilizing agent.

V. Stella, J. Haslam, V J Stella, 2001, Journal of pharmaceutical sciences.

The use of cyclodextrins in ophthalmic formulations of dipivefrin

A. Urtti, V. Stella, K. Järvinen, 1997 .

A case for prodrugs: Fosphenytoin

V. Stella, 1996 .

Mechanism of decarboxylation of p-aminosalicylic acid.

V. Stella, S. G. Jivani, 1985, Journal of pharmaceutical sciences.

Stability of Drugs and Dosage Forms

V. Stella, S. Yoshioka, 2000, Springer US.

Hydrolysis of pharmaceutically relevant phosphate monoester monoanions: correlation to an established structure-reactivity relationship.

V. Stella, A. Kearney, 1993, Journal of pharmaceutical sciences.

Dissolution kinetics of carboxylic acids II: effect of buffers.

M. Mintun, V. Stella, K. Himmelstein, 1981, Journal of pharmaceutical sciences.

Systemic bioavailability of penclomedine (NSC-338720) from oil-in-water emulsions administered intraduodenally to rats

Valentino J. Stella, Robert A. Myers, V. Stella, 1992 .

Properties of a model aryl boronic acid and its boroxine.

E. Munson, V. Stella, V. Day, 2012, Journal of pharmaceutical sciences.

The nucleophilicity of dextrose, sucrose, sorbitol, and mannitol with p-nitrophenyl esters in aqueous solution.

Valentino J. Stella, V. Stella, R. Killion, 1990 .

Degradation of NSC-281612 (4-[bis[2-[(methylsulfonyl)oxy]ethyl]amino]-2-methyl-benzaldehyde), an experimental antineoplastic agent: effects of pH, solvent composition, (SBE)7m-beta-CD, and HP-beta-CD on stability.

V. Stella, S. Silchenko, M. Jumaa, 2004, Journal of pharmaceutical sciences.

Determination of the position of the ester bond in a micellar prodrug of phenytoin

A. P. Lötter, V. Stella, D. G. Müller, 1994 .

Ionization kinetics of the carbon acid phenindione.

V. Stella, R. Gish, 1979, Journal of pharmaceutical sciences.

Directed Drug Delivery

Valentino J. Stella, Ronald T. Borchardt, R. Borchardt, 1985, Experimental Biology and Medicine.

Macromolecular Prodrugs of Small Molecules

V. Stella, W. Marinaro, 2007 .

Effect of Molecular Structure on the Relative Hydrogen Peroxide Scavenging Ability of Some α-Keto Carboxylic Acids.

V. Stella, A. Lopalco, 2016, Journal of pharmaceutical sciences.

Derivatives of melphalan designed to enhance drug accumulation in cancer cells.

R T Borchardt, R. Borchardt, K. Tamura, 1997, Journal of drug targeting.

Prodrugs of Amides, Imides and Other NH-acidic Compounds

V. Stella, Victor R. Guarino, 2007 .

Hydrolysis and dissolution behavior of a prolonged-release prodrug of theophylline: 7,7'-succinylditheophylline.

V. Stella, T. Higuchi, H. K. Lee, 1979, Journal of pharmaceutical sciences.

The Chemistry of a Novel 5,5-Diphenylhydantoin Pro-drug

V. Stella, T. Higuchi, A. Hussain, 1975 .

The Metabolic Disposition of a Novel 5,5-Diphenylhydantoin Pro-drug

A. Glazko, W. Dill, V. Stella, 1975 .

Esters of hydantoic acids as prodrugs of hydantoins.

V. Stella, T. Higuchi, 1973, Journal of pharmaceutical sciences.

A novel prodrug approach for tertiary amines. 2. Physicochemical and in vitro enzymatic evaluation of selected N-phosphonooxymethyl prodrugs.

V. Stella, J. Krise, S. Narisawa, 1999, Journal of pharmaceutical sciences.

Prodrugs: My Initial Exploration and Where It Led.

V. Stella, 2020, Journal of pharmaceutical sciences.

Factors influencing the precipitation time of phenytoin in the presence of DDMS, one of its prodrugs

A. P. Lötter, V. Stella, D. G. Müller, 1991 .

Phenytoin prodrugs V: In vivo evaluation of some water-soluble phenytoin prodrugs in dogs.

S. Varia, V. Stella, 1984, Journal of pharmaceutical sciences.

Low-melting phenytoin prodrugs as alternative oral delivery modes for phenytoin: a model for other high-melting sparingly water-soluble drugs.

V. Stella, Y. Yamaoka, V J Stella, 1983, Journal of pharmaceutical sciences.

Evaluation of the prodrug potential of the sulfate esters of acetaminophen and 3-hydroxymethyl-phenytoin

S. Varia, V. Stella, Desmond B. Williams, 1983 .

Novel prodrug approach for tertiary amines: synthesis and preliminary evaluation of N-phosphonooxymethyl prodrugs.

V. Stella, G. Georg, J. Zygmunt, 1999, Journal of medicinal chemistry.

Stability of carmethizole hydrochloride (NSC-602668), an experimental cytotoxic agent

V. Stella, R. Killion, W. Anderson, 1991 .

Interaction of model aryl- and alkyl-boronic acids and 1,2-diols in aqueous solution.

V. Stella, R. Prankerd, W. Marinaro, 2015, Journal of pharmaceutical sciences.

Prodrug Approaches to Enhancing the Oral Delivery of Poorly Permeable Drugs

V. Stella, 2007 .

Dissolution of carboxylic acids. III: The effect of polyionizable buffers.

V. Stella, J. Auniņš, R. A. Myers, 1985, Journal of pharmaceutical sciences.

Prodrugs as therapeutics

V. Stella, 2004 .

Prodrugs

V. Stella, W. Charman, V. Naringrekar, 1985, Drugs.

Radiochemical plasma salicylamide assay using ring-labeled tritiated salicylamide.

S. Varia, V. Stella, M. Riedy, 1979, Journal of pharmaceutical sciences.

Degradation of the antineoplastic drug, clomesone (2-chloroethyl(methylsulfonyl) methanesulfonate, NSC-338947). A kinetic and mechanistic study

V. Stella, C. Riley, P. Kennedy, 1988 .

Mechanistic investigation of the degradation of sulfamic acid 1,7-heptanediyl ester, an experimental cytotoxic agent, in water and 18oxygen-enriched water.

V. Stella, M. Paborji, W. Waugh, 1987, Journal of pharmaceutical sciences.

Development of reversed-phase HPLC assays for cyclodisone and clomesone.

V. Stella, C. Riley, P. Kennedy, 1987, Journal of pharmaceutical and biomedical analysis.

Prodrugs of peptides and proteins for improved formulation and delivery.

R. Oliyai, V. Stella, 1993, Annual review of pharmacology and toxicology.

Pharmacokinetics of 2-butanol and its metabolites in the rat

V. Stella, K. Himmelstein, G. Traiger, 1981, Journal of Pharmacokinetics and Biopharmaceutics.

Effects of lipid class and lipid vehicle volume on the intestinal lymphatic transport of DDT

Valentino J. Stella, V. Stella, W. Charman, 1986 .

Thiamine whole blood and urinary pharmacokinetics in rats: urethan-induced dose-dependent pharmacokinetics.

V. Stella, J. Pipkin, 1982, Journal of pharmaceutical sciences.

Rapid expansion from supercritical solutions: application to pharmaceutical processes

Valentino J. Stella, Elaine M. Phillips, V. Stella, 1993 .

Applicability of (SBE)7m-β-CD in controlled-porosity osmotic pump tablets (OPTs)

V. Stella, K. Uekama, T. Irie, 2004 .

Prodrug strategies to enhance the intestinal absorption of peptides

R. Borchardt, V. Stella, G. Pauletti, 1997 .

Release mechanisms of a sparingly water-soluble drug from controlled porosity-osmotic pump pellets using sulfobutylether-beta-cyclodextrin as both a solubilizing and osmotic agent.

V. Stella, Ping I. Lee, S. Sotthivirat, 2009, Journal of pharmaceutical sciences.

Evaluation of various properties of alternative salt forms of sulfobutylether-beta-cyclodextrin, (SBE)7M-beta-CD.

V. Stella, S. Sotthivirat, J. Haslam, 2007, International journal of pharmaceutics.

Controlled porosity-osmotic pump pellets of a poorly water-soluble drug using sulfobutylether-beta-cyclodextrin, (SBE) 7M-beta-CD, as a solubilizing and osmotic agent.

V. Stella, S. Sotthivirat, J. Haslam, 2007, Journal of pharmaceutical sciences.

Is ICRF-187 [(+)-1,2-Bis(3,5-dioxopiperazinyl-1-yl)propane] Unusually Reactive for an Imide?

V. Stella, J. Sisco, 1992, Pharmaceutical Research.

New injectable melphalan formulations utilizing (SBE)(7m)-beta-CD or HP-beta-CD.

V. Stella, R. Rajewski, D. Q. Ma, 1999, International journal of pharmaceutics.

Aqueous solubility and dissolution rate does not adequately predict in vivo performance: a probe utilizing some N-acyloxymethyl phenytoin prodrugs.

V. Stella, S. Martodihardjo, V J Stella, 1999, Journal of pharmaceutical sciences.

An analytical method to determine small quantities of phenytoin in the presence of excess amounts of one of its prodrugs, the monomethane sulphonate salt of 3-(N,N-dimethylglycyloxymethyl)-5,5-diphenyl-hydantoin.

V. Stella, D. Muller, 1987, Journal of pharmaceutical and biomedical analysis.

A mechanistic and kinetic study of the beta-lactone hydrolysis of Salinosporamide A (NPI-0052), a novel proteasome inhibitor.

V. Stella, N. Denora, B. Potts, 2007, Journal of pharmaceutical sciences.

Urinary and biliary disposition of the lactone and carboxylate forms of 20(S)-camptothecin in rats.

D. Bindra, D. Scott, V. Stella, 1994, Drug metabolism and disposition: the biological fate of chemicals.

Use of trimethylanilinium hydroxide-tetramethylammonium hydroxide as on-column methylating agent for GLC analysis of phenytoin.

V. Stella, 1977, Journal of pharmaceutical sciences.

An experimental system designed to study the in situ intestinal lymphatic transport of lipophilic drugs in anesthetized rats

V. Stella, W. Charman, T. Noguchi, 1986 .

Effect of short-term exposure to polychlorinated biphenyls on first-pass metabolism of pentobarbital in rats.

V. Stella, C. Chu, 1980, Journal of pharmaceutical sciences.

Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine.

V. Stella, Victor R. Guarino, J. Hemenway, 2007, Bioorganic & medicinal chemistry letters.

Pro-drugs as Novel Drug Delivery Systems

V. Stella, T. Higuchi, T. Higuchi, 1975 .

Enhancement of Transport of D-Melphalan Analogue by Conjugation with L-Glutamate across Bovine Brain Microvessel Endothelial Cell Monolayers

K. Audus, V. Stella, T. Sakaeda, 2000, Journal of drug targeting.

Solvolytic reactions of cyclic anhydrides in anhydrous acetic acid.

M. Haddadin, V. Stella, T. Higuchi, 1975, Journal of pharmaceutical sciences.

Factors affecting membrane-controlled drug release for an osmotic pump tablet (OPT) utilizing (SBE)(7m)-beta-CD as both a solubilizer and osmotic agent.

V. Stella, K. Uekama, T. Irie, 1999, Journal of controlled release : official journal of the Controlled Release Society.

The Pharmaceutical Use of Captisol®: Some Surprising Observations

V. Stella, V. Rao, E. Zannou, 2002 .

Release of testosterone from an osmotic pump tablet utilizing (SBE)7m-beta-cyclodextrin as both a solubilizing and an osmotic pump agent.

V. Stella, R. Rajewski, K. Okimoto, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Osmotic Properties of Sulfobutylether and Hydroxypropyl Cyclodextrins

V. Stella, W. Streng, E. Zannou, 2001, Pharmaceutical Research.

Isolation, Solubility, and Characterization of D-Mannitol Esters of 4-Methoxybenzeneboronic Acid.

V. Stella, V. Day, A. Lopalco, 2017, Journal of pharmaceutical sciences.

The Effect of SBE7-β-CD with Viscous Vehicle on Ocular Delivery of Pilocarpine Prodrug in Rabbits

A. Urtti, V. Stella, P. Jarho, 1996 .

Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720; 3,5-dichloro-2,4-dimethoxy-6-trichloromethylpyridine): a novel, practically water insoluble cytotoxic agent.

V. Stella, R. Prankerd, S. G. Frank, 1988, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

In vitro conversion of model sulfenamide prodrugs in the presence of small molecule thiols.

V. Stella, K. Nti-Addae, 2011, Journal of pharmaceutical sciences.

The effect of SBE4-β-CD on i.v. methylprednisolone pharmacokinetics in rats: Comparison to a co-solvent solution and two water-soluble prodrugs

Valentino J. Stella, V. Stella, H. K. Lee, 1995 .

Pharmacokinetic profile and safety of intravenous NEPA, a fixed combination of fosnetupitant and palonosetron, in cancer patients: Prevention of chemotherapy-induced nausea and vomiting associated with highly emetogenic chemotherapy.

V. Stella, A. Bernareggi, G. Kurteva, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Dissolution kinetics of carboxylic acids I: effect of pH under unbuffered conditions.

M A Mintun, M. Mintun, V. Stella, 1981, Journal of pharmaceutical sciences.

Determination of pKa and Hydration Constants for a Series of α-Keto-Carboxylic Acids Using Nuclear Magnetic Resonance Spectrometry.

V. Stella, J. Douglas, N. Denora, 2016, Journal of pharmaceutical sciences.

Challenges in the Development of Intravenous Neurokinin‐1 Receptor Antagonists: Results of a Safety and Pharmacokinetics Dose‐Finding, Phase 1 Study of Intravenous Fosnetupitant

A. Venturini, V. Stella, C. Giuliano, 2022, Clinical pharmacology in drug development.

Degradation pathways of a peptide boronic acid derivative, 2-Pyz-(CO)-Phe-Leu-B(OH)(2).

V. Stella, S. Wu, W. Waugh, 2000, Journal of pharmaceutical sciences.

On the mechanism of isomerization of cephalosporin esters.

V. Stella, W. Richter, Y. Chong, 1990, Journal of pharmaceutical sciences.

Nonclassical phase transfer behavior of phenylbutazone.

V. Stella, 1975, Journal of pharmaceutical sciences.

Enhancement of bioavailability of a hydrophobic amine antimalarial by formulation with oleic acid in a soft gelatin capsule.

N. Yata, V. Stella, J. Haslam, 1978, Journal of pharmaceutical sciences.

Phenylbutazone ionization kinetics.

V. Stella, J. Pipkin, 1976, Journal of pharmaceutical sciences.

Pro-drugs as novel drug delivery systems : a symposium

V. Stella, T. Higuchi, 1975 .

Mechanism of Degradation of an α-Keto-Epoxide, a Model for the Warhead for Various Proteasome Inhibitor Anticancer Agents.

V. Stella, C. D. Ablan, A. Lopalco, 2017, Journal of pharmaceutical sciences.

The effect of SBE4-β-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: Comparison to a co-solvent solution and a water-soluble prodrug

V. Stella, H. K. Lee, D. Thompson, 1995 .

The effect of drug lipophilicity and lipid vehicles on the lymphatic absorption of various testosterone esters

V. Stella, W. Charman, T. Noguchi, 1985 .

Thiamine whole blood pharmackinetics in rats using both a specific S-thiamine liquid scintillation assay and the thiochrome fluorescence assay.

V. Stella, J. Pipkin, 1978, Journal of pharmaceutical sciences.

Structural Factors affecting the kinetics of O,N-acyl transfer in potential O-peptide prodrugs

R. Oliyai, V. Stella, 1995 .

A liquid chromatographic method for the determination of the enantiomeric purity of the anticancer drug, 9-amino-20(S)-camptothecin.

V. Stella, C. Riley, J. Kagel, 1993, Journal of pharmaceutical and biomedical analysis.

Prodrugs : challenges and rewards

Valentino J. Stella, V. Stella, 2007 .

Pro-drugs as drug delivery systems XXI. Preparation, physicochemical properties and bioavailability of a novel water-soluble pro-drug type for carbamazepine☆

V. Stella, H. Bundgaard, M. Cortese, 1982 .

Blood and lymph transport of DDT after oral and parenteral administration to anaesthetised rats

V. Stella, C. O’Driscoll, R. A. Myers, 1991 .

Non-isothermal stability by linear heating: a fast method for preformulation stability screening of drugs at the discovery and development interface

V. Stella, Shaoxin Feng, Thomas K. Karami, 2017 .

Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells.

V. Stella, G. Dalwadi, Victor R. Guarino, 2012, Journal of pharmaceutical sciences.

Some relationships between the physical properties of various 3-acyloxymethyl prodrugs of phenytoin to structure: potential in vivo performance implications.

V. Stella, S. Martodihardjo, V. Rao, 1998, Journal of pharmaceutical sciences.

Phenytoin prodrugs VI: In vivo evaluation of a phosphate ester prodrug of phenytoin after parenteral administration to rats.

S. Varia, V. Stella, 1984, Journal of pharmaceutical sciences.

Sulfobutyl ether-alkyl ether mixed cyclodextrin derivatives with enhanced inclusion ability.

V. Stella, T. Ozeki, S. Tongiani, 2009, Journal of Pharmacy and Science.

Kinetics of the acid-catalyzed closure of hydantoic acids. Effect of 2-aryl and 2-alkyl substituents

V. Stella, T. Higuchi, 1973 .

Chemical and physical bases determining the instability and incompatibility of formulated injectable drugs.

V. Stella, 1986, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

Synthesis of an esterase-sensitive cyclic prodrug of a model hexapeptide having enhanced membrane permeability and enzymatic stability using an acyloxyalkoxy promoiety.

R. Borchardt, V. Stella, G. Pauletti, 1999, Methods in molecular medicine.

Drug release from membranes of hyaluronic acid and its esters

E. Topp, V. Stella, H. Joshi, 1992 .

Dosage forms from polymeric prodrugs : hydrocortisone esters of hyaluronic acid

J. A. Hunt, E. Topp, V. Stella, 1991 .

Case Study: Fosphenytoin: A Prodrug of Phenytoin

V. Stella, 2007 .

Bortezomib Aqueous Solubility in the Presence and Absence of D-Mannitol: A Clarification with Formulation Implications.

V. Stella, R. Iacobazzi, N. Denora, 2020, Journal of pharmaceutical sciences.

A preliminary Pharmacokinetic study of dianhydrogalactitol (NSC-132313) disposition in the dog.

V. Stella, T. Higuchi, L. Sternson, 1977, Journal of the National Cancer Institute.

Prodrugs: Some thoughts and current issues.

V. Stella, 2010, Journal of pharmaceutical sciences.

ESTERS OF HYDANTOIC ACIDS AS PRODRUGS OF HYDANTOINS

V. Stella, T. Higuchi, 1973 .

Extrathermodynamic relations in the binding of charged and neutral substrates to sulfobutylether-β-CDs (SBE-β-CDs) and a 2-hydroxypropyl-β-CD (HP-β-CD)

V. Stella, V. J. Stella, D. Velde, 2014, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

Cyclodextrins

V. Stella, Q. He, 2008, Toxicologic pathology.

Testing potential dosage form strategies for intestinal lymphatic drug transport: studies in the rat

V. Stella, W. Charman, T. Noguchi, 1986 .

Release mechanisms of a sparingly water-soluble drug from controlled porosity-osmotic pump pellets using sulfobutylether-beta-cyclodextrin as both a solubilizing and osmotic agent.

V. Stella, Ping I. Lee, S. Sotthivirat, 2009, Journal of pharmaceutical sciences.

Your prodrug releases formaldehyde: should you be concerned? No!

V. Stella, S. Dhareshwar, 2008, Journal of pharmaceutical sciences.

Dissolution of lonizable Drugs into Unbuffered Solution: A Comprehensive Model for Mass Transport and Reaction in the Rotating Disk Geometry

Don W. Green, Valentino J. Stella, D. Green, 2004, Pharmaceutical Research.

Degradation of O6-Benzylguanine in Aqueous Polyethylene Glycol 400 (PEG 400) Solutions: Concerns with Formaldehyde in PEG 400

D. Bindra, V. Stella, T. Williams, 1994, Pharmaceutical Research.

Mechanisms of drug release from cyclodextrin complexes.

Zia, V. Stella, Stella, 1999, Advanced drug delivery reviews.