S. Wing

发表

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase.

T. Hunter, Han-kuei Huang, C. Joazeiro, 1999, Science.

FAM210A is a novel determinant of bone and muscle structure and strength

J. Richards, John A. Morris, S. Wing, 2018, Proceedings of the National Academy of Sciences.

Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response

A. Iavarone, R. Cencic, J. Pelletier, 2017, Endocrinology.

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy.

A. Goldberg, S. Wing, R. Medina, 1995, The Biochemical journal.

Interactions of the Super Complexes: When mTORC1 Meets the Proteasome.

S. Wing, S. Kimball, Olasunkanmi A J Adegoke, 2019, The international journal of biochemistry & cell biology.

Ubiquitin Ligase Huwe1 Modulates Spermatogenesis by Regulating Spermatogonial Differentiation and Entry into Meiosis

S. Wing, C. O’Flaherty, M. Culty, 2017, Scientific Reports.

Purification and properties of a NAD(P)H:flavin oxidoreductase from the luminous bacterium, Beneckea harveyi.

S. Wing, E. Meighen, G. Michaliszyn, 1977, The Journal of biological chemistry.

Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal men.

R. Gougeon, S. Wing, S. Kimball, 2009, American journal of physiology. Endocrinology and metabolism.

Complement modulates the function of the ubiquitin-proteasome system and endoplasmic reticulum-associated degradation in glomerular epithelial cells.

Thomas M. Kitzler, S. Wing, Julie Guillemette, 2012, Biochimica et biophysica acta.

Expression of the Ubiquitin Proteasome System in Neonatal Rat Gonocytes and Spermatogonia: Role in Gonocyte Differentiation1

S. Wing, M. Culty, G. Manku, 2012, Biology of reproduction.

Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2

Kai-Florian Storch, S. Wing, Junmin Peng, 2012, Biology Open.

Ataxin-3 Deubiquitination Is Coupled to Parkin Ubiquitination via E2 Ubiquitin-conjugating Enzyme*

Thomas M. Durcan, S. Wing, E. Fon, 2011, The Journal of Biological Chemistry.

Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting.

A. Goldberg, S. Wing, 1993, The American journal of physiology.

Association of Low Muscle Mass With Cognitive Function During a 3-Year Follow-up Among Adults Aged 65 to 86 Years in the Canadian Longitudinal Study on Aging

E. Rahme, S. Wing, J. Morais, 2022, JAMA network open.

Endocrine regulation of protein breakdown in skeletal muscle.

A. Goldberg, S. Wing, I. Kettelhut, 1988, Diabetes/metabolism reviews.

normal men protein anabolism and modulates glucose disposal in Fed-state clamp stimulates cellular mechanisms of muscle

José A. Morais, Stéphanie Chevalier, Scot R. Kimball, 2013 .

USP19 is a ubiquitin-specific protease regulated in rat skeletal muscle during catabolic states.

V. Baracos, D. Attaix, S. Wing, 2005, American journal of physiology. Endocrinology and metabolism.

Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation.

A. Goldberg, S. Wing, A. Haas, 1995, The Biochemical journal.

Deubiquitinating enzymes in skeletal muscle atrophy-An essential role for USP19.

S. Wing, 2016, The international journal of biochemistry & cell biology.

Mechanisms involved in 3',5'-cyclic adenosine monophosphate-mediated inhibition of the ubiquitin-proteasome system in skeletal muscle.

S. Wing, S. Lecker, I. Kettelhut, 2009, Endocrinology.

Activation of the ubiquitin-ATP-dependent proteolytic system in skeletal muscle during fasting and denervation atrophy.

A. Goldberg, S. Wing, R. Medina, 1991, Biomedica biochimica acta.

Ubiquitin-conjugating enzyme E214k/HR6B is dispensable for increased protein catabolism in muscle of fasted mice.

S. Wing, H. Roest, N. Bédard, 2002, American journal of physiology. Endocrinology and metabolism.

USP2 Regulates the Intracellular Localization of PER1 and Circadian Gene Expression

S. Wing, N. Cermakian, J. Fahrenkrug, 2014, Journal of biological rhythms.

Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats.

A. Goldberg, S. Wing, J. Dice, 1991, The Biochemical journal.

Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.

R. Cencic, J. Pelletier, M. Tremblay, 2012, Cancer research.

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation.

S. Wing, Erin S Coyne, P. Bilodeau, 2016, American journal of physiology. Cell physiology.

is Dispensable for the Increase in Protein Catabolism

S. Wing, H. Roest, N. Bédard, 2002 .

skeletal muscle during catabolic states USP19 is a ubiquitin-specific protease regulated in rat

V. Baracos, D. Attaix, S. Wing, 2005 .

Proparathyroid Hormone-related Protein Is Associated with the Chaperone Protein BiP and Undergoes Proteasome-mediated Degradation*

K. Meerovitch, S. Wing, D. Goltzman, 1998, The Journal of Biological Chemistry.

Regulated expression of the ubiquitin protein ligase, E3Histone/LASU1/Mule/ARF‐BP1/HUWE1, during spermatogenesis

S. Wing, L. Hermo, Q. Xia, 2007, Developmental dynamics : an official publication of the American Association of Anatomists.

A proinflammatory tumor that activates protein degradation sensitizes rats to catabolic effects of endotoxin.

V. Baracos, S. Wing, N. Bédard, 2005, American journal of physiology. Endocrinology and metabolism.

A rabbit reticulocyte ubiquitin carrier protein that supports ubiquitin-dependent proteolysis (E214k) is homologous to the yeast DNA repair gene RAD6.

S. Wing, D. Banville, F. Dumas, 1992, The Journal of biological chemistry.

The deubiquitinating enzyme USP19 modulates adipogenesis and potentiates high-fat-diet-induced obesity and glucose intolerance in mice

S. Wing, M. Faraj, A. Tchernof, 2018, Diabetologia.

USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1

K. Nakayama, S. Wing, Dongmei Cheng, 2009, Molecular and Cellular Biology.

A New Method of Purification of Proteasome Substrates Reveals Polyubiquitination of 20 S Proteasome Subunits*

D. Taillandier, D. Attaix, S. Wing, 2007, Journal of Biological Chemistry.

Mice Lacking the USP2 Deubiquitinating Enzyme Have Severe Male Subfertility Associated with Defects in Fertilization and Sperm Motility1

D. Cyr, S. Wing, L. Hermo, 2011, Biology of reproduction.

Mice Lacking the USP 2 Deubiquitinating Enzyme Have Severe Male Subfertility Associated with Defects in Fertilization and Sperm Motility 1

D. Cyr, S. Wing, L. Hermo, 2011 .

Effect of heart failure on the regulation of skeletal muscle protein synthesis, breakdown, and apoptosis.

D. Matthews, M. LeWinter, S. Wing, 2003, American journal of physiology. Endocrinology and metabolism.

Divergent N-Terminal Sequences Target an Inducible Testis Deubiquitinating Enzyme to Distinct Subcellular Structures

P. Hingamp, S. Wing, L. Combaret, 2000, Molecular and Cellular Biology.

Ubiquitin-proteasome system in spermatogenesis.

S. Wing, M. Culty, G. Manku, 2014, Advances in experimental medicine and biology.

USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling

S. Wing, A. Cybulsky, L. Larose, 2015, Molecular biology of the cell.

USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1

K. Nakayama, S. Wing, Dongmei Cheng, 2008, Molecular and Cellular Biology.

Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

S. Wing, L. Pinsky, B. Gottlieb, 2002, Journal of molecular endocrinology.

A Novel Rat Homolog of the Saccharomyces cerevisiae Ubiquitin-Conjugating Enzymes UBC4 and UBC5 with Distinct Biochemical Features Is Induced during Spermatogenesis

P. Hingamp, S. Wing, J. Trasler, 2005, Molecular and Cellular Biology.

Characterization of E3Histone, a Novel Testis Ubiquitin Protein Ligase Which Ubiquitinates Histones

R. Oughtred, S. Wing, Zhiqian Liu, 2005, Molecular and Cellular Biology.

Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testis.

S. Wing, P. Jain, Simon S. Wing, 1995, The Biochemical journal.

Divergent N-terminal Sequences of a Deubiquitinating Enzyme Modulate Substrate Specificity*

Luming Yin, K. Wilkinson, S. Wing, 2001, The Journal of Biological Chemistry.

Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks

S. Wing, S. Lecker, R. Jagoe, 2011, Critical reviews in clinical laboratory sciences.

Mice Lacking the UBC4-testis Gene Have a Delay in Postnatal Testis Development but Normal Spermatogenesis and Fertility

P. Hingamp, D. Cyr, S. Wing, 2005, Molecular and Cellular Biology.

Functions of the ubiquitin system in mammalian spermatogenesis and skeletal muscle

S. Wing, Zhiyu Pang, 2011 .

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

Kalle Gehring, Nahum Sonenberg, Madoka Yoshida, 2006, The EMBO journal.

Deubiquitinating enzymes--the importance of driving in reverse along the ubiquitin-proteasome pathway.

S. Wing, 2003, The international journal of biochemistry & cell biology.

Preproparathyroid Hormone-related Protein, a Secreted Peptide, Is a Substrate for the Ubiquitin Proteolytic System*

K. Meerovitch, S. Wing, D. Goltzman, 1997, The Journal of Biological Chemistry.

S-Nitrosylation of IRP2 Regulates Its Stability via the Ubiquitin-Proteasome Pathway

S. Wing, P. Ponka, Sangwon F. Kim, 2004, Molecular and Cellular Biology.

Identification of Distinctive Patterns of USP19-Mediated Growth Regulation in Normal and Malignant Cells

S. Wing, S. Chevalier, N. Bédard, 2011, PloS one.

The UPS in diabetes and obesity

S. Wing, 2008, BMC Biochemistry.

A novel rat homolog of the Saccharomyces cerevisiae ubiquitin-conjugating enzymes UBC4 and UBC5 with distinct biochemical features is induced during spermatogenesis

P. Hingamp, S. Wing, J. Trasler, 1996, Molecular and cellular biology.

Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

R. Sladek, O. Bathe, S. Wing, 2018, Endocrinology.

Inactivation of the ubiquitin‐specific protease 19 deubiquitinating enzyme protects against muscle wasting

V. Baracos, S. Wing, S. Chevalier, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

USP19-deubiquitinating enzyme regulates levels of major myofibrillar proteins in L6 muscle cells.

S. Wing, Lu Yu, P. Sundaram, 2009, American journal of physiology. Endocrinology and metabolism.

S-Nitrosylation of IRP 2 Regulates Its Stability via the Ubiquitin-Proteasome Pathway

S. Wing, P. Ponka, Sangwon F. Kim, 2003 .

Identification of Amino Acid Residues in a Class I Ubiquitin-conjugating Enzyme Involved in Determining Specificity of Conjugation of Ubiquitin to Proteins*

R. Oughtred, S. Wing, A. Vrielink, 1998, The Journal of Biological Chemistry.

A central role for ubiquitination within a circadian clock protein modification code

S. Wing, N. Cermakian, Katarina Stojkovic, 2014, Front. Mol. Neurosci..

Characterization of rat100, a 300-kilodalton ubiquitin-protein ligase induced in germ cells of the rat testis and similar to the Drosophila hyperplastic discs gene.

R. Oughtred, S. Wing, V. Rajapurohitam, 2002, Endocrinology.

The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting

Takla Griss, Russell G. Jones, A. Pause, 2018, EMBO molecular medicine.

Physical function‐derived cut‐points for the diagnosis of sarcopenia and dynapenia from the Canadian longitudinal study on aging

E. Rahme, S. Wing, J. Morais, 2019, Journal of cachexia, sarcopenia and muscle.

14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin.

S. Wing, D. Banville, 1994, The American journal of physiology.

Activation of a UBC4-dependent pathway of ubiquitin conjugation during postnatal development of the rat testis.

S. Wing, V. Rajapurohitam, M. El‐Alfy, 1999, Developmental biology.

BH3‐ligand regulates access of MCL‐1 to its E3 ligase

M. Blanchette, M. Warr, S. Wing, 2005, FEBS letters.

Control of ubiquitination in skeletal muscle wasting.

S. Wing, 2005, The international journal of biochemistry & cell biology.

Deubiquitinases in skeletal muscle atrophy.

S. Wing, 2013, The international journal of biochemistry & cell biology.

Control of ubiquitination of proteins in rat tissues by ubiquitin conjugating enzymes and isopeptidases.

S. Wing, V. Rajapurohitam, N. Bédard, 2002, American journal of physiology. Endocrinology and metabolism.

The business of deubiquitination – location, location, location

S. Wing, Erin S Coyne, 2016, F1000Research.

Genetic inactivation of the USP19 deubiquitinase regulates a-synuclein ubiquitination and inhibits accumulation of Lewy body like aggregates in mice

Y. Ye, S. Wing, N. Bédard, 2022, bioRxiv.

Abstract LB-087: Discovery and development of first-in-class orally bioavailable USP19 inhibitors

X. Jacq, S. Wing, M. Wappett, 2019, Molecular and Cellular Biology / Genetics.

Identification of Rabbit Reticulocyte E217K as a UBC7 Homologue and Functional Characterization of Its Core Domain Loop*

S. Wing, Haijiang Lin, 1999, The Journal of Biological Chemistry.

USP 19-deubiquitinating enzyme regulates levels of major myofibrillar proteins in L 6 muscle cells

S. Wing, Lu Yu, P. Sundaram, 2009 .

Insulin-like growth factor I stimulates degradation of an mRNA transcript encoding the 14 kDa ubiquitin-conjugating enzyme.

S. Wing, N. Bédard, 1996, The Biochemical journal.

Ubiquitin Ligase Huwe1 Modulates Spermatogenesis by Regulating Spermatogonial Differentiation and Entry into Meiosis

S. Wing, C. O’Flaherty, M. Culty, 2017, Scientific Reports.

Role of the deubiquitinating enzyme ubiquitin-specific protease-14 in proteostasis in renal cells.

S. Wing, J. Papillon, A. Cybulsky, 2016, American journal of physiology. Renal physiology.