Andrew J. Wilson

发表

Photocatalytic proximity labelling of MCL-1 by a BH3 ligand

Hester A. Beard, Jacob R. Hauser, M. Walko, 2019, Communications Chemistry.

Inhibition of α-helix-mediated protein-protein interactions using designed molecules.

Andrew J. Wilson, V. Azzarito, Kérya Long, 2013, Nature chemistry.

Helix-mediated protein–protein interactions as targets for intervention using foldamers

Thomas A. Edwards, Andrew J. Wilson, T. Edwards, 2011, Amino Acids.

Inhibition of protein-protein interactions using designed molecules.

Andrew J. Wilson, 2009, Chemical Society reviews.

Modeling of Arylamide Helix Mimetics in the p53 Peptide Binding Site of hDM2 Suggests Parallel and Anti-Parallel Conformations Are Both Stable

Jonathan C. Fuller, M. Shirts, R. Jackson, 2012, PloS one.

Predicting and Experimentally Validating Hot-Spot Residues at Protein–Protein Interfaces

Gail J. Bartlett, R. Sessions, D. Woolfson, 2019, ACS chemical biology.

Organic “Magic Rings”: The Hydrogen Bond-Directed Assembly of Catenanes under Thermodynamic Control

David A. Leigh, Andrew J. Wilson, D. Leigh, 1999 .

Peptide-based inhibitors of protein–protein interactions: biophysical, structural and cellular consequences of introducing a constraint

M. Walko, Andrew J. Wilson, Xiaohui Wang, 2021, Chemical science.

Tunable Self-Assembled Elastomers Using Triply Hydrogen-Bonded Arrays

Andrew J. Wilson, A. Saiani, C. Lindsay, 2012 .

Helix mimetics: Recent developments.

Andrew J. Wilson, 2015, Progress in biophysics and molecular biology.

Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

S. Radford, Andrew J. Wilson, T. Karamanos, 2020, Journal of the American Chemical Society.

Hydrogen‐Bonding Receptors for Molecular Guests

Andrew J. Wilson, 2012 .

Pattern recognition of proteins based on an array of functionalized porphyrins.

A. Hamilton, Andrew J. Wilson, Huchen Zhou, 2006, Journal of the American Chemical Society.

Interfacing native and non-native peptides: using Affimers to recognise α-helix mimicking foldamers.

Andrew J Wilson, Andrew J. Wilson, Anna Barnard, 2017, Chemical communications.

Towards “bionic” proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterisation; additional biophysical data. See DOI: 10.1039/

A. Breeze, S. Warriner, A. Nelson, 2016, Chemical communications.

Activity‐Directed Synthesis of Inhibitors of the p53/hDM2 Protein–Protein Interaction

Adam Nelson, S. Warriner, A. Nelson, 2020, Chemistry.

Photocatalytic proximity labelling of MCL-1 by a BH3 ligand

Hester A. Beard, Jacob R. Hauser, M. Walko, 2019, Communications Chemistry.

Structural optimization of reversible dibromomaleimide peptide stapling

M. Walko, Andrew J. Wilson, C. Pask, 2020, Peptide science.

Stapled Peptides as HIF‐1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency

R. Sessions, A. Nelson, Andrew J. Wilson, 2020, Chemistry.

Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation

R. Sessions, L. Lian, Andrew J. Wilson, 2020, Chemical science.

Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

S. Radford, Andrew J. Wilson, T. Karamanos, 2020, Journal of the American Chemical Society.

Protein sensing and discrimination using highly functionalised ruthenium(ii) tris(bipyridyl) protein surface mimetics in an array format.

Andrew J. Wilson, Sarah H. Hewitt, 2017, Chemical communications.

Inter-domain dynamics in the chaperone SurA and multi-site binding to its unfolded outer membrane protein clients

S. Radford, R. Tuma, P. White, 2019, bioRxiv.

Predicting and Experimentally Validating Hot-Spot Residues at Protein–Protein Interfaces

R. Sessions, D. Woolfson, A. Nelson, 2019, ACS chemical biology.

Linear shear and nonlinear extensional rheology of unentangled supramolecular side-chain polymers

Victor A. H. Boudara, Qian Huang, O. Hassager, 2018, Journal of Rheology.

Synthesis of peptidomimetic scaffolds

Andrew J. Wilson, 2013 .

Probing Protein Surfaces: QSAR Analysis with Helix Mimetics

S. Warriner, Andrew J. Wilson, V. Azzarito, 2016, Chembiochem : a European journal of chemical biology.

Protein surface recognition using geometrically pure Ru(ii) tris(bipyridine) derivatives† †This article is part of the ‘Emerging Investigators’ themed issue for ChemComm ‡ ‡Electronic supplementary information (ESI) available: Synthetic procedures, characterization and fluorescence binding studies.

A. Ashcroft, Andrew J. Wilson, J. Muldoon, 2010, Chemical communications.

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

S. Radford, R. Tuma, P. White, 2020, Nature Communications.

The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs

A. Breeze, N. Zanchin, M. Walko, 2018, Nucleic acids research.

Design and synthesis of cysteine-specific labels for photo-crosslinking studies

S. Radford, M. Walko, Andrew J. Wilson, 2019, RSC advances.

Side-Chain Supramolecular Polymers Employing Conformer Independent Triple Hydrogen Bonding Arrays

Andrew J. Wilson, N. Murphy, Adam Gooch, 2013, Macromolecules.

Assembly of miscible supramolecular network blends using DDA·AAD hydrogen-bonding interactions of pendent side-chains

Andrew J. Wilson, J. Mattsson, S. Connell, 2020, Polymer Chemistry.

Design, synthesis and binding studies of a novel quadruple ADDA hydrogen-bond array.

Andrew J. Wilson, J. Fisher, Maria L. Pellizzaro, 2012, Organic & biomolecular chemistry.

Conformer-independent ureidoimidazole motifs--tools to probe conformational and tautomeric effects on the molecular recognition of triply hydrogen-bonded heterodimers.

Andrew J. Wilson, M. Nix, J. Fisher, 2011, Chemistry.

Ditopic triply hydrogen-bonded heterodimers.

Andrew J. Wilson, J. Fisher, C. Lindsay, 2011, Organic & biomolecular chemistry.

Solid-state structures of ureidoimidazoles

Andrew J. Wilson, C. Kilner, Jeffrey Plante, 2011 .

Substituent control over dimerization affinity of triply hydrogen bonded heterodimers.

Andrew J. Wilson, C. Lindsay, Adam Gooch, 2011, Organic letters.

Design, synthesis and binding properties of conformer-independent linear ADA hydrogen-bonding arrays

Andrew J. Wilson, C. Lindsay, Adam Gooch, 2009 .

Conformer independent heterodimerisation of linear arrays using three hydrogen bonds.

Andrew J. Wilson, C. Kilner, Andrea M. McGhee, 2008, Chemical communications.

The Use of Electrospray Mass Spectrometry to Determine Speciation in a Dynamic Combinatorial Library for Anion Recognition

A. Ashcroft, Andrew J. Wilson, H. I. Phillips, 2012, Chemistry.

The mechanism of formation of amide-based interlocked compounds: prediction of a new rotaxane-forming motif.

Andrew J. Wilson, F. Zerbetto, D. Leigh, 2004, Chemistry.

"Magic rod" rotaxanes: the hydrogen bond-directed synthesis of molecular shuttles under thermodynamic control.

David A Leigh, Jeffrey S. Hannam, Andrew J Wilson, 2003, Organic letters.

Sequential and phototriggered supramolecular self-sorting cascades using hydrogen-bonded motifs

Andrew J. Wilson, Kelly. A. Houton, Maria L. Pellizzaro, 2013 .

Macrocyclic scaffolds derived from p-aminobenzoic acid.

Andrew J. Wilson, M. Hardie, T. Prior, 2007, Chemical communications.

Protein Surface Mimetics: Understanding How Ruthenium Tris(Bipyridines) Interact with Proteins

Andrew J. Wilson, M. Webb, L. T. Kuhn, 2016, Chembiochem : a European journal of chemical biology.

Metal complexes as "protein surface mimetics".

Andrew J. Wilson, Sarah H. Hewitt, 2016, Chemical communications.

Recognition of solvent exposed protein surfaces using anthracene derived receptors.

S. Fletcher, A. Hamilton, Andrew J. Wilson, 2007, Organic & biomolecular chemistry.

Chiral amplification in the transcription of supramolecular helicity into a polymer backbone.

E. W. Meijer, Andrew J. Wilson, R. Sijbesma, 2005, Angewandte Chemie.

Expedient synthesis of benzene tricarboxamide macrocycles derived from p-aminobenzoic acid

Andrew J. Wilson, C. Kilner, F. Campbell, 2010 .

Selective protein-surface sensing using ruthenium(II) tris(bipyridine) complexes.

Andrew J Wilson, A. Ashcroft, Andrew J. Wilson, 2010, Chemistry.

Inhibition of protein-protein interactions using designed molecules.

Andrew J. Wilson, A. J. Wilson, 2009, Chemical Society reviews.

Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6ob00078a Click here for additional data file.

A. Breeze, S. Warriner, A. Nelson, 2016, Organic & biomolecular chemistry.

Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics.

Andrew J. Wilson, Kérya Long, T. Edwards, 2013, Bioorganic & medicinal chemistry.

N-alkylated oligoamide alpha-helical proteomimetics.

S. Warriner, Andrew J. Wilson, T. Edwards, 2010, Organic & biomolecular chemistry.

Oligobenzamide proteomimetic inhibitors of the p53–hDM2 protein–protein interaction† †Electronic supplementary information (ESI) available: Synthetic procedures, protein expression and FP assays. See DOI: 10.1039/b908207g Click here for additional data file.

Jeffrey P. Plante, Thomas Burnley, Barbora Malkova, 2009, Chemical communications.

An ‘impossible’ macrocyclisation using conformation directing protecting groups

Andrew J. Wilson, F. Campbell, 2009 .

Synthesis of functionalised aromatic oligamide rods.

S. Warriner, Andrew J. Wilson, C. Kilner, 2008, Organic & biomolecular chemistry.

Pattern-based detection of different proteins using an array of fluorescent protein surface receptors.

Laura Baldini, Andrew J Wilson, A. Hamilton, 2004, Journal of the American Chemical Society.

A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00374f

S. Warriner, Andrew J. Wilson, M. Webb, 2019, Chemical science.

Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions

A. Nelson, Andrew J. Wilson, T. Edwards, 2017, Chemical science.

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.

A. Breeze, S. Warriner, A. Nelson, 2015, Molecular bioSystems.

Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions**

Andrew J. Wilson, Kérya Long, T. Edwards, 2015, Angewandte Chemie.

Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03559c Click here for additional data file.

S. Warriner, Andrew J. Wilson, V. Azzarito, 2015, Chemical science.

Multivalent helix mimetics for PPI-inhibition.

Andrew J. Wilson, Anna Barnard, George M. Burslem, 2015, Organic & biomolecular chemistry.

Orthogonal functionalisation of α-helix mimetics† †Electronic supplementary information (ESI) available: Additional binding data and fluorescence characterisation. Experimental procedures and characterisation of all new compounds. See DOI: 10.1039/c4ob00915k Click here for additional data file.

David J. Yeo, Andrew J. Wilson, V. Azzarito, 2014, Organic & biomolecular chemistry.

Small-Molecule Proteomimetic Inhibitors of the HIF-1α–p300 Protein–Protein Interaction

A. Breeze, S. Warriner, A. Nelson, 2014, Chembiochem : a European journal of chemical biology.

Synthesis of Oligobenzamide α-Helix Mimetics

Andrew J. Wilson, George M. Burslem, 2013 .

Aromatic Oligoamide Foldamers with a "Wet Edge" as Inhibitors of the α- Helix-Mediated p53-hDM2 Protein-Protein Interaction

Andrew J. Wilson, N. Murphy, T. Edwards, 2013 .

Solid-Phase Methodology for Synthesis of O-Alkylated Aromatic Oligoamide Inhibitors of α-Helix-Mediated Protein–Protein Interactions

S. Warriner, Andrew J. Wilson, V. Azzarito, 2013, Chemistry.

2-O-alkylated para-benzamide α-helix mimetics: the role of scaffold curvature.

S. Warriner, Andrew J. Wilson, V. Azzarito, 2012, Organic & biomolecular chemistry.

Conformational properties of O-alkylated benzamides

S. Warriner, Andrew J. Wilson, V. Azzarito, 2012 .

An α‐Helix‐Mimicking 12,13‐Helix: Designed α/β/γ‐Foldamers as Selective Inhibitors of Protein–Protein Interactions

Andrew J. Wilson, S. Robin, D. Aitken, 2016, Angewandte Chemie.

Control of conformation in α-helix mimicking aromatic oligoamide foldamers through interactions between adjacent side-chains.

Andrew J. Wilson, M. Webb, D. Tomlinson, 2019, Organic & biomolecular chemistry.

Direct Detection of Hydrogen Bonds in Supramolecular Systems Using 1H–15N Heteronuclear Multiple Quantum Coherence Spectroscopy

A. Burnett, Andrew J. Wilson, S. Goldup, 2022, Journal of the American Chemical Society.

Supramolecular Self‐Sorting Networks using Hydrogen‐Bonding Motifs

M. Howard, Andrew J. Wilson, Stephanie C C van der Lubbe, 2018, Chemistry.

Directed denaturation: room temperature and stoichiometric unfolding of cytochrome C by a metalloporphyrin dimer.

A. Hamilton, Andrew J. Wilson, R. Jain, 2003, Journal of the American Chemical Society.

In celebration of the 60th birthday of Professor Andrew D. Hamilton FRS.

Andrew J. Wilson, A. Battersby, Sam Thompson, 2013, Organic & biomolecular chemistry.

Non-covalent polymer assembly using arrays of hydrogen-bonds.

Andrew J. Wilson, 2007, Soft matter.

Design, synthesis and conformational analyses of bifacial benzamide based foldamers

Andrew J. Wilson, N. Murphy, H. Shepherd, 2015 .

A pH‐Switchable Triple Hydrogen‐Bonding Motif

Andrew J. Wilson, B. Blight, B. Balónová, 2020, ChemistryOpen.

Development of solvent-free synthesis of hydrogen-bonded supramolecular polyurethanes

Andrew J. Wilson, George M. Burslem, Kelly. A. Houton, 2015, Chemical science.

Monosubstituted alkenyl amino acids for peptide "stapling".

David J. Yeo, S. Warriner, Andrew J. Wilson, 2013, Chemical communications.

Hydrogen‐bonded supramolecular polyurethanes

Andrew J. Wilson, Kelly. A. Houton, 2015 .

Amplification of chirality in benzene tricarboxamide helical supramolecular polymers.

E. W. Meijer, Andrew J. Wilson, R. Sijbesma, 2006, Chemical communications.

Protein destabilisation by ruthenium(II) tris-bipyridine based protein-surface mimetics.

A. Ashcroft, Andrew J. Wilson, J. Ault, 2013, Organic & biomolecular chemistry.

Structural insights into peptide self‐assembly using photo‐induced crosslinking experiments and discontinuous molecular dynamics

S. Radford, C. Hall, Andrew J. Wilson, 2020, AIChE journal. American Institute of Chemical Engineers.

Analysis of Amyloid Nanostructures Using Photo-cross-linking: In Situ Comparison of Three Widely Used Photo-cross-linkers

S. Radford, G. Preston, A. Ashcroft, 2013, ACS chemical biology.

Covalent cross-linking within supramolecular peptide structures.

S. Radford, G. Preston, A. Ashcroft, 2012, Analytical chemistry.

Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β40 (Aβ40) by the peptide fragment Aβ16–22

S. Radford, C. Hall, A. Ashcroft, 2019, Science Advances.

Thermodynamic phase diagram of amyloid-β (16–22) peptide

S. Auer, S. Radford, C. Hall, 2019, Proceedings of the National Academy of Sciences.

Photo-induced covalent cross-linking for the analysis of biomolecular interactions.

G. Preston, Andrew J. Wilson, 2013, Chemical Society reviews.

Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers

S. Radford, M. Walko, Andrew J. Wilson, 2018, Angewandte Chemie.

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation.

M. J. Parker, S. Radford, A. Ashcroft, 2008, Chemical communications.

Modulators of 14-3-3 Protein–Protein Interactions

L. M. Stevers, M. Hann, C. Ottmann, 2017, Journal of medicinal chemistry.

Understanding p300-transcription factor interactions using sequence variation and hybridization

R. Sessions, Andrew J. Wilson, T. Edwards, 2021, bioRxiv.

Visualizing and trapping transient oligomers in amyloid assembly pathways

S. Radford, Andrew J. Wilson, T. Karamanos, 2020, Biophysical chemistry.

Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction

C. Ottmann, Andrew J. Wilson, A. Gunnarsson, 2022, Journal of medicinal chemistry.

Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products

C. Ottmann, I. Landrieu, Andrew J. Wilson, 2020, Journal of the American Chemical Society.

Query-guided protein–protein interaction inhibitor discovery†

R. Sessions, D. Woolfson, D. M. Andrews, 2021, Chemical science.

Understanding the interaction of 14‐3‐3 proteins with hDMX and hDM2: a structural and biophysical study

C. Ottmann, S. Warriner, Andrew J. Wilson, 2021, bioRxiv.

Enhanced Suppression of a Protein-Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead.

I. Hamachi, Andrew J. Wilson, Tomonori Tamura, 2021, Journal of the American Chemical Society.

Selective and Potent Proteomimetic Inhibitors of Intracellular Protein–Protein Interactions†

Andrew J. Wilson, Kérya Long, T. Edwards, 2015, Angewandte Chemie.

Targeting trimeric transmembrane domain 5 of oncogenic latent membrane protein 1 using a computationally designed peptide† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02474c

K. Mineev, Andrew J. Wilson, Xiaozheng Zhang, 2019, Chemical science.

Metal Complexes as “Protein Surface Mimetics”

Andrew J. Wilson, Sarah H. Hewitt, 2016 .

Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds

Jin-jian Lu, C. Leung, Dik‐Lung Ma, 2016, Oncotarget.

The wide-field, multiplexed, spectroscopic facility WEAVE: Survey design, overview, and simulated implementation

S. R. Berlanas, Sergey E. Koposov, H. Rottgering, 2022, Monthly Notices of the Royal Astronomical Society.

Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the alpha or beta catalytic subunit.

Andrew J. Wilson, B. Perrino, L. Clapp, 2002, European journal of biochemistry.

Dynamic Combinatorial Chemistry. In Drug Discovery, Bioorganic Chemistry, and Materials Science. Herausgegeben von Benjamin L. Miller.

Andrew J. Wilson, 2010 .

Targeting the transmembrane domain 5 of latent membrane protein 1 using small molecule modulators.

K. Mineev, Andrew J. Wilson, Bo Zhang, 2021, European journal of medicinal chemistry.

Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs**

J. Clarke, Andrew J. Wilson, T. Edwards, 2020, Chembiochem : a European journal of chemical biology.

BAlaS: fast, interactive and accessible computational alanine-scanning using BudeAlaScan

Derek N Woolfson, Christopher W Wood, Amaurys A Ibarra, 2020, Bioinform..

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

S. Radford, R. Tuma, P. White, 2020, Nature Communications.

Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS)

R. Sessions, D. Woolfson, S. Dutt, 2021, RSC Chemical Biology.

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

J. Clarke, Andrew J. Wilson, T. Edwards, 2019, bioRxiv.

De novo coiled-coil peptides as scaffolds for disrupting protein–protein interactions† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02643b

D. Woolfson, Jordan M Fletcher, Andrew J. Wilson, 2018, Chemical science.

Chemical sensing: Nanonose for sniffing out proteins.

Andrew J Wilson, Andrew J. Wilson, 2009, Nature chemistry.

Photo‐Induced Covalent Cross‐Linking for the Analysis of Biomolecular Interactions

G. Preston, Andrew J. Wilson, 2013 .

A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00374f

S. Warriner, Andrew J. Wilson, M. Webb, 2019, Chemical science.

α-Helix stabilization by co-operative side chain charge-reinforced interactions to phosphoserine in a basic kinase-substrate motif

R. Bayliss, Andrew J. Wilson, Robert S Dawber, 2021, bioRxiv.

Recognition of ASF1 by Using Hydrocarbon‐Constrained Peptides

F. Ochsenbein, Andrew J. Wilson, Z. Hegedüs, 2019, Chembiochem : a European journal of chemical biology.

Catalytic unfolding and proteolysis of cytochrome C induced by synthetic binding agents.

A. Hamilton, Andrew J. Wilson, K. Groves, 2004, Journal of the American Chemical Society.

Generation of Dynamic Combinatorial Libraries Using Hydrazone‐Functionalized Surface Mimetics

Andrew J. Wilson, Sarah H. Hewitt, 2018, European journal of organic chemistry.