N. Gohain

发表

Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2018, Chemical science.

From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses

M. Pazgier, W. Tolbert, N. Gohain, 2019, mAbs.

Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240

E. Sundberg, M. Pazgier, Wuyuan Lu, 2016, Scientific Reports.

Full Length Single Chain Fc Protein (FLSC IgG1) as a Potent Antiviral Therapy Candidate: Implications for In Vivo Studies.

M. Reitz, R. Redfield, M. Pazgier, 2016, AIDS research and human retroviruses.

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques

M. Pazgier, W. Tolbert, N. Gohain, 2022, Frontiers in Immunology.

Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG3

M. Pazgier, W. Tolbert, N. Gohain, 2019 .

The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa.

N. Gohain, W. Blankenfeldt, L. Thomashow, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Army liposome formulation containing QS-21 render human monocyte-derived macrophages less permissive to HIV-1 infection by upregulating APOBEC3A

N. Gohain, G. Matyas, C. Alving, 2022, Scientific Reports.

Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses

G. Cavet, R. Redfield, M. Sajadi, 2018, Cell.

Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression

M. Pazgier, Wuyuan Lu, Wangxiao He, 2021, Acta pharmaceutica Sinica. B.

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

Laura L. Sutherland, B. Haynes, D. Montefiori, 2021, PLoS pathogens.

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

Gregory D. Gromowski, M. Diamond, P. McTamney, 2021, Cell Reports.

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

Gregory D. Gromowski, M. Diamond, P. McTamney, 2021, bioRxiv.

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

J. Sodroski, D. Kaufmann, C. Tremblay, 2016, EBioMedicine.

Structural basis of how stress-induced MDMX phosphorylation activates p53

M. Pazgier, Weiyue Lu, Wuyuan Lu, 2016, Oncogene.

Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site

M. Pazgier, W. Tolbert, N. Gohain, 2020, BMC Biology.

Induction of Fc-Mediated Effector Functions Against a Stabilized Inner Domain of HIV-1 gp120 Designed to Selectively Harbor the A32 Epitope Region

M. Pazgier, W. Tolbert, N. Gohain, 2019, Front. Immunol..

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

J. Foulke, M. Sajadi, P. Acharya, 2014, Journal of Virology.

Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding.

P. Wintrode, M. Pazgier, W. Tolbert, 2020, Structure.

Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region.

M. Pazgier, W. Tolbert, N. Gohain, 2017, Structure.

Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region

M. Pazgier, W. Tolbert, N. Gohain, 2016, Structure.

Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1

M. Sajadi, P. Acharya, P. Kwong, 2015, Journal of Virology.

HIV-1 Infection Response Implicated in Reduced Risk for Antibody-Dependent Cellular Cytotoxicity Structural Definition of an

J. Foulke, M. Sajadi, P. Acharya, 2014 .

Studies on the structure and function of phenazine modifying enzymes PhzM and PhzS involved in the biosynthesis of pyocyanin

N. Gohain, W. Blankenfeldt, 2009 .

The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa.

N. Gohain, W. Blankenfeldt, L. Thomashow, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.

Jerome H. Kim, P. Zhang, E. Go, 2020, JCI insight.

Systematic mutational analysis of human neutrophil α-defensin HNP4.

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2019, Biochimica et biophysica acta. Biomembranes.

Design of a potent antibiotic peptide based on the active region of human defensin 5.

T. Cheng, M. Pazgier, W. Tolbert, 2015, Journal of medicinal chemistry.

Humoral Response to the HIV-1 Envelope V2 Region in a Thai Early Acute Infection Cohort

Peter T. Pham, E. Sanders-Buell, M. Robb, 2019, Cells.

Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.

Weam I Zaky, Gregory D. Gromowski, Hongjun Bai, 2023, Cell Reports.

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

Gregory D. Gromowski, M. Diamond, P. McTamney, 2021, Cell Reports.

Determination of Binding Affinity of Antibodies to HIV-1 Recombinant Envelope Glycoproteins, Pseudoviruses, Infectious Molecular Clones, and Cell-Expressed Trimeric gp160 Using Microscale Thermophoresis

N. Gohain, Hung V. Trinh, M. Rao, 2023, Cells.