Yan Zou

发表

Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design

M. Pazgier, Weirong Yuan, Wuyuan Lu, 2018, Chemical science.

Different stapling-based peptide drug design: Mimicking α-helix as inhibitors of protein–protein interaction

Xiang Li, Honggang Hu, Yan Zou, 2018, Chinese Chemical Letters.

A novel peptide stapling strategy enables the retention of ring-closing amino acid side chains for the Wnt/β-catenin signalling pathway† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02420g Click here for additional data file.

Ye Guang Chen, Xiang Li, Honggang Hu, 2017, Chemical science.

Design, Synthesis and Antifungal Activity of Stapled Aurein1.2 Peptides

Xiang Li, Yan Zou, Lin-jing Zhao, 2021, Antibiotics.

A silver-promoted solid-phase guanidylation process enables the first total synthesis of stictamide A

Xiang Li, Honggang Hu, Yan Zou, 2015 .

Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents.

Honggang Hu, Yan Zou, Lei Zhang, 2013, Bioorganic & medicinal chemistry letters.

Atropisomer Control in Macrocyclic Factor VIIa Inhibitors.

L. Mueller, D. Cheney, Yan Zou, 2016, Journal of medicinal chemistry.

Total Synthesis and Antibacterial Study of Cyclohexapeptides Desotamide B, Wollamide B and Their Analogs

Xiang Li, Honggang Hu, Yan Zou, 2018, Chemistry & biodiversity.

Synthesis and antibacterial activities of novel tyrocidine A glycosylated derivatives towards multidrug‐resistant pathogens

Xiang Li, Honggang Hu, Yan Zou, 2015, Journal of peptide science : an official publication of the European Peptide Society.

Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors.

D. Cheney, C. Weigelt, Yan Zou, 2013, Bioorganic & medicinal chemistry letters.

Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process.

Yan Zou, Qiu-ye Wu, Xiaoyun Chai, 2015, Chemical communications.

Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulators.

L. Hamann, A. Fura, R. Seethala, 2007, Bioorganic & medicinal chemistry letters.

d-Amino acid mutation of PMI as potent dual peptide inhibitors of p53-MDM2/MDMX interactions.

Xiang Li, Honggang Hu, Yan Zou, 2017, Bioorganic & medicinal chemistry letters.

Synthesis, Biological Evaluation, and Molecular Docking Studies of Xanthone Sulfonamides as ACAT Inhibitors

Xiang Li, Honggang Hu, Yan Zou, 2015, Chemical biology & drug design.

First identification of xanthone sulfonamides as potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.

Honggang Hu, Yan Zou, Hong-Li Liao, 2010, Bioorganic & medicinal chemistry letters.

Novel Aryl Boronate Ester Based Amino Acids as Orthogonal Building Blocks for Fmoc Solid Phase Peptide Synthesis

Honggang Hu, Yan Zou, Yuanye Jiang, 2017 .

Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.

Wen Jiang, D. Cheney, Yan Zou, 2016, Bioorganic & medicinal chemistry letters.

Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.

Brandon L. Parkhurst, Wen Jiang, D. Cheney, 2016, Journal of medicinal chemistry.

Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.

Wen Jiang, D. Cheney, Yan Zou, 2014, ACS medicinal chemistry letters.

Synthesis and antifungal activity of the novel triazole compounds

Honggang Hu, Yan Zou, Qingyan Sun, 2013 .

Design, synthesis and molecular docking studies of sinomenine derivatives.

Honggang Hu, Yan Zou, Qiu-ye Wu, 2012, Bioorganic & medicinal chemistry letters.

N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.

K. Kish, L. Hamann, A. Fura, 2009, Journal of medicinal chemistry.

A facile and efficient method for synthesis of macrocyclic lipoglycopeptide

Xiang Li, Honggang Hu, Yan Zou, 2015 .

Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates.

Xiang Li, Honggang Hu, Yan Zou, 2014, European journal of medicinal chemistry.

Design, synthesis and molecular docking studies of novel triazole as antifungal agent.

Yan Zou, Yuan-Ying Jiang, Yongbing Cao, 2011, European journal of medicinal chemistry.

Enantioselective [3+2] cycloadditions of terminal allenoates with β-sulfonyl-α,β-unsaturated ketones

Yan Zou, Huamin Wang, Xiuzheng Li, 2022, Green Synthesis and Catalysis.

New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies.

Honggang Hu, Yan Zou, Qiu-ye Wu, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase.

Honggang Hu, Yan Zou, Qingyan Sun, 2010, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols.

Honggang Hu, Yan Zou, Da-Zhi Zhang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and preliminary immunologic properties of di-/trisaccharide-conjugates related to Bacillus anthracis.

Yan Zou, Xiao-bin Zhuo, Qiu-ye Wu, 2022, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro antitumor activities of xanthone derivatives containing 1,4-disubstituted-1,2,3-triazole moiety

Honggang Hu, Yan Zou, Qiu-ye Wu, 2012, Archives of pharmacal research.

Synthesis and antifungal activity of the novel triazole derivatives containing 1,2,3-triazole fragment

Yan Zou, Qingyan Sun, Qiu-ye Wu, 2013, Archives of pharmacal research.

Synthesis and Biological Evaluation of Kojic Acid Derivatives Containing 1,2,4‐triazole as Potent Tyrosinase Inhibitors

Yunhui Zhao, Yan Zou, Wenlin Xie, 2015, Chemical biology & drug design.

Synthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents.

Yan Zou, Yuan-Ying Jiang, Yongbing Cao, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.

Yan Zou, Yuan-Ying Jiang, Yongbing Cao, 2011, European journal of medicinal chemistry.

Design, synthesis and antifungal evaluation of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-1H-1,2,4-triazol-5(4H)-one.

Honggang Hu, Yan Zou, Yuan-Ying Jiang, 2011, European journal of medicinal chemistry.

Solid-Phase Synthesis of Cyclic Heptapeptide Stylissatin A

Yan Zou, Yu-lei Li, Chao-mei Liu, 2016, Chemistry of Natural Compounds.

One-pot synthesis of 7-bromo-1-[4-(1-cyano-1-methylethyl)]-phenyl-[1,2,4]-triazole-[4,3-a]-quinoxalin

Honggang Hu, Yan Zou, Yan Yang, 2009 .

Facile Synthesis of the Pentasaccharide Repeating Unit of the Exopolysaccharide from Cryptococcus neoformans Serotype D

Honggang Hu, Yan Zou, Shengjun Huang, 2015 .

Synthesis and biological evaluation of novel fluconazole analogues bearing 1,3,4-oxadiazole moiety as potent antifungal agents

Yan Zou, Lei Zhang, Qiu-ye Wu, 2015, Archives of pharmacal research.

Synthesis and evaluation of novel azoles as potent antifungal agents.

Yan Zou, Qiu-ye Wu, Xiaoyun Chai, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and Antifungal Activities of Glycosylated Derivatives of the Cyclic Peptide Fungicide Caspofungin

Honggang Hu, Yan Zou, Zhongwu Guo, 2012, ChemMedChem.

Synthesis and biological evaluation of novel fluconazole analogues bearing 1,3,4-oxadiazole moiety as potent antifungal agents

Yan Zou, Lei Zhang, Qiu-ye Wu, 2014, Archives of Pharmacal Research.

Synthesis and antifungal activity of the novel triazole derivatives containing 1,2,3-triazole fragment

Yan Zou, H. Cui, Qingyan Sun, 2013, Archives of Pharmacal Research.

GPR84 inhibitor ameliorated lung inflammation and modulated NF-κB through MAPK signalling pathway

Yan Zou, Ting Wang, H. Lv, 2021 .

Configuration-Specific Antibody for Bacterial Heptosylation: An Antiadhesion Therapeutic Strategy.

Wuyuan Lu, Xiang Li, Yan Zou, 2022, Journal of the American Chemical Society.

Design, synthesis, and biological evaluation of novel 1, 2, 4-triazole derivatives as antifungal agent

Yan Zou, Yongbing Cao, Qingyan Sun, 2012, Archives of Pharmacal Research.

Metabolic activation and major protein target of a 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonist.

Yan Zou, J. Yabut, J. Shang, 2012, Chemical research in toxicology.

Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors.

Yan Zou, Guigen Li, Yu-Shun Yang, 2016, Bioorganic & medicinal chemistry.

Synthesis, In Vitro Biological Evaluation, and Molecular Docking of New Triazoles as Potent Antifungal Agents

Xiang Li, Honggang Hu, Yan Zou, 2016, Archiv der Pharmazie.

Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications.

Haixia Wang, Stanley R Krystek, Jacek Ostrowski, 2007, Journal of medicinal chemistry.

Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors.

Yan Zou, R. Wexler, J. Muckelbauer, 2023, Bioorganic & medicinal chemistry letters.

SOS1-inspired hydrocarbon-stapled peptide as a pan-Ras inhibitor.

Xiang Li, Yan Zou, Conghao Gai, 2023, Bioorganic chemistry.

Solid-Phase Synthesis of Cyclic Heptapeptide Stylissatin A

Yan Zou, Yu-lei Li, Yuan Gao, 2016, Chemistry of Natural Compounds.

Synthesis and Antifungal Evaluation of Novel Triazole Derivatives as Inhibitors of Cytochrome P450 14α-Demethylase.

Honggang Hu, Yan Zou, Qingyan Sun, 2011 .

Peptide stapling with the retention of double native side-chains

Xiang Li, Honggang Hu, Yan Zou, 2021 .

Design, synthesis, and antiproliferative activities of stapled melittin peptides

Yan Zou, Chao-mei Liu, Bai Li, 2017 .

Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice.

Xiang Li, Honggang Hu, Yan Zou, 2018, European journal of medicinal chemistry.

Synthesis and antifungal activities of N-glycosylated derivatives of Tunicyclin D, an antifungal octacyclopeptide

Honggang Hu, Yan Zou, Qiu-ye Wu, 2014 .

pDobz/pDobb protected diaminodiacid as a novel building block for peptide disulfide-bond mimic synthesis

L. Qin, Honggang Hu, Yan Zou, 2019, RSC advances.

Diaminodiacid-based synthesis of macrocyclic peptides using 1,2,3-triazole bridges as disulfide bond mimetics

Honggang Hu, Yan Zou, Qiu-ye Wu, 2017 .

Synthesis and Biological Evaluation of Triazole Derivatives as Potential Antifungal Agent

Yan Zou, Yongbing Cao, Qingyan Sun, 2012, Chemical biology & drug design.

Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process.

Yan Zou, Qiu-ye Wu, Xiaoyun Chai, 2015, Chemical communications.