Rongshi Li

发表

Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine-G-Protein-Coupled-Receptor Interface.

Yan Liu, Rongshi Li, M Trent Kemp, 2016, Journal of medicinal chemistry.

Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells.

Ying Sun, S. Ekins, P. Swaan, 2008, Journal of medicinal chemistry.

Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach.

Rongshi Li, S. Morris, Alan Pourpak, 2009, Journal of medicinal chemistry.

Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine

Yan Liu, B. Volkman, Emmanuel W Smith, 2014, Journal of medicinal chemistry.

Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.

Yan Liu, B. Volkman, Emmanuel W Smith, 2013, Current topics in medicinal chemistry.

Merrifield MicroTubeTM reactors for solid phase synthesis

A. W. Czarnik, Rongshi Li, Xiao-yi Xiao, 1998 .

Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters.

Rongshi Li, Pengfei Li, Wenjun Li, 2019, Organic letters.

Kinase Inhibitor Drugs

Rongshi Li, J. Stafford, 2009 .

Polystyrene grafted fluoropolymer microtubes: New supports for solid-phase organic synthesis with useful performance at high temperature

A. W. Czarnik, Rongshi Li, C. Zhao, 1999 .

Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.

Rongshi Li, Jian Wang, Rongshi Li, 2006, Journal of medicinal chemistry.

Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach.

Rongshi Li, S. Morris, Alan Pourpak, 2009, Journal of medicinal chemistry.

Enamine Catalytic Annulation of Azonaphthalenes: An Access to Indole Derivatives.

Rongshi Li, Wenjun Li, H. Yuan, 2019, Organic letters.

Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products

Rongshi Li, 2016, Medicinal research reviews.

Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential.

Rongshi Li, P. Lograsso, Rongshi Li, 2016, Journal of medicinal chemistry.

Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy.

Rongshi Li, J. Bernatchez, Y. Luan, 2018, Journal of medicinal chemistry.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, Antimicrobial Agents and Chemotherapy.

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation*

Yan Liu, Shen-Shu Sung, Rongshi Li, 2012, The Journal of Biological Chemistry.

Marinopyrrole Derivatives as Potential Antibiotic Agents against Methicillin-Resistant Staphylococcus aureus (III)

V. Nizet, M. Hensler, Yan Liu, 2014, Marine drugs.

Marinopyrrole Derivatives as Potential Antibiotic Agents against Methicillin-Resistant Staphylococcus aureus (I)

V. Nizet, M. Hensler, Yan Liu, 2012, Marine drugs.

Drugs for the Treatment of Zika Virus Infection.

Rongshi Li, J. Bernatchez, J. Siqueira-Neto, 2020, Journal of medicinal chemistry.

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

Development of anaplastic lymphoma kinase (ALK) small‐molecule inhibitors for cancer therapy

Rongshi Li, S. Morris, 2008, Medicinal research reviews.

Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors.

W. Guida, Yan Liu, S. Sebti, 2012, Journal of medicinal chemistry.

Assessment of Tissue Distribution and Metabolism of MP1, a Novel Pyrrolomycin, in Mice Using a Validated LC-MS/MS Method

Rongshi Li, D. Coulter, D. Murry, 2020, Molecules.

Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway.

Rongshi Li, Jianguo Wu, Dongsheng Xu, 2016, Current topics in medicinal chemistry.

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

Ab initio and molecular dynamics study of dibenzotricyclic calcium antagonists: A rigid model approach

R. J. Boyd, A. Laaksonen, Rongshi Li, 1994 .

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

Yan Liu, S. Sebti, Rongshi Li, 2013, Oncogene.

Novel fluorinated pyrrolomycins as potent anti-staphylococcal biofilm agents: Design, synthesis, pharmacokinetics and antibacterial activities.

Yan Liu, Jialin C. Zheng, Zhen Qiao, 2016, European journal of medicinal chemistry.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Yan Liu, Zhen Qiao, 2019, BMC Cancer.

Design and Synthesis of Human Immunodeficiency Virus Entry Inhibitors: Sulfonamide as an Isostere for the α-Ketoamide Group

Rongshi Li, D. Bolognesi, S. Fisher, 2007 .

Analogs of Marinopyrrole A Show Enhancement to Observed In Vitro Potency against Acute Toxoplasma gondii Infection

Yan Liu, Rongshi Li, R. C. Warner, 2021, Antimicrobial agents and chemotherapy.

Natural Product‐Based Drug Discovery

Rongshi Li, Rongshi Li, 2016, Medicinal research reviews.

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Yan Liu, Zhen Qiao, Rongshi Li, 2019, BMC Cancer.

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

Yan Liu, Rongshi Li, J. Bernatchez, 2018, bioRxiv.

A Spectrophotometric Determination of α-Dicarbonyl Compounds and Its Application to the Enzymatic Formation of α-Ketobutyrate

G. L. Kenyon, Rongshi Li, 1995 .

Development of anaplastic lymphoma kinase (ALK) small‐molecule inhibitors for cancer therapy

Rongshi Li, S. Morris, Stephan W. Morris, 2008, Medicinal research reviews.

Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues.

G. Petsko, G. L. Kenyon, J. Gerlt, 1991, Biochemistry.

Marinopyrrole Derivatives as Potential Antibiotic Agents against Methicillin-Resistant Staphylococcus aureus (II)

Jerry Li, Yan Liu, Rongshi Li, 2013, Marine Drugs.

Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors.

Yan Liu, Rongshi Li, Jerry Li, 2015, European journal of medicinal chemistry.

Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Yan Liu, Rongshi Li, J. Siqueira-Neto, 2018, Antimicrobial Agents and Chemotherapy.

Structure-based design of parasitic protease inhibitors.

R J Fletterick, F E Cohen, G L Kenyon, 1996, Bioorganic & medicinal chemistry.