A. Ferrer-Montiel

发表

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators.

M. Martín-Martínez, I. Gomez-Monterrey, M. Bonache, 2014, ACS combinatorial science.

A synthetic hexapeptide (Argireline) with antiwrinkle activity.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2002, International journal of cosmetic science.

Attenuation of thermal nociception and hyperalgesia by VR1 blockers

Antonio Ferrer-Montiel, Teresa Carbonell, Marco Caprini, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Molecular Modeling of the Full-length Human TRPV1 Channel in Closed and Desensitized States

G. Fernández-Ballester, A. Ferrer-Montiel, G. Fernández-Ballester, 2008, Journal of Membrane Biology.

Molecular Compatibility of the Channel Gate and the N Terminus of S5 Segment for Voltage-gated Channel Activity*

S. Ferroni, G. Fernández-Ballester, A. Ferrer-Montiel, 2005, Journal of Biological Chemistry.

Potentiation of the Transient Receptor Potential Vanilloid 1 Channel Contributes to Pruritogenesis in a Rat Model of Liver Disease*

V. Felipo, C. Montoliu, A. Ferrer-Montiel, 2013, The Journal of Biological Chemistry.

Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade.

J. González-Ros, F. Albericio, A. Fernández-Carvajal, 2011, ACS combinatorial science.

Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2020, Expert opinion on therapeutic targets.

Highly Functionalized 1,2–Diamino Compounds through Reductive Amination of Amino Acid-Derived β–Keto Esters

J. González-Ros, A. Fernández-Carvajal, A. Ferrer-Montiel, 2013, PloS one.

Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival

A. Ferrer-Montiel, H. Cabedo, Christelle Carteron, 2006, Journal of Cell Science.

Recent progress in non-opioid analgesic peptides.

A. Ferrer-Montiel, R. González-Muñiz, M. J. Pérez de Vega, 2018, Archives of biochemistry and biophysics.

Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier.

A. Ferrer-Montiel, A. Messeguer, E. Prats, 2016, European journal of medicinal chemistry.

The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains

U. Schubert, A. Ferrer-Montiel, M. Montal, 1996, Journal of virology.

The 26‐mer peptide released from SNAP‐25 cleavage by botulinum neurotoxin E inhibits vesicle docking

J. Canaves, A. Ferrer-Montiel, M. Montal, 1998, FEBS letters.

β–Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, International journal of molecular sciences.

Adamantyl Analogues of Paracetamol as Potent Analgesic Drugs via Inhibition of TRPA1

J. Elguero, A. Fernández-Carvajal, A. Ferrer-Montiel, 2014, PloS one.

TRP Channel Trafficking

A. Ferrer-Montiel, R. Planells‐Cases, R. Planells-Cases, 2007 .

Molecular Determinants of the Sensory and Motor Neuron-derived Factor Insertion into Plasma Membrane*

Asia M. Fernández, J. Gallar, A. Ferrer-Montiel, 2002, The Journal of Biological Chemistry.

GAP43 stimulates inositol trisphosphate‐mediated calcium release in response to hypotonicity

C. Belmonte, A. Ferrer-Montiel, M. Caprini, 2003, The EMBO journal.

Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation

R. Proia, C. Bandtlow, Rüdiger Schweigreiter, 2017, Front. Mol. Neurosci..

Rab4 interacts with the human P‐glycoprotein and modulates its surface expression in multidrug resistant K562 cells

A. Fernández-Carvajal, A. Ferrer-Montiel, Clotilde Ferrándiz-Huertas, 2011, International journal of cancer.

Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis

E. Pérez-Payá, H. Fearnhead, A. Ferrer-Montiel, 2006, Cell Death and Differentiation.

Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents.

E. Pérez-Payá, A. Ferrer-Montiel, A. Messeguer, 2005, Bioorganic & medicinal chemistry.

Neurotrophins, endocannabinoids and thermo‐transient receptor potential: a threesome in pain signalling

A. Ferrer-Montiel, I. Devesa, 2014, The European journal of neuroscience.

Trimers of N-Alkylglycines Are Potent Modulators of the Multidrug Resistance Phenotype

E. Pérez-Payá, A. Ferrer-Montiel, A. Messeguer, 2005, Journal of Pharmacology and Experimental Therapeutics.

Paclitaxel in vitro reversibly sensitizes the excitability of IB4(−) and IB4(+) sensory neurons from male and female rats

A. Fernández-Carvajal, A. Ferrer-Montiel, R. de la Torre-Martinez, 2022, British journal of pharmacology.

Small peptides patterned after the N‐terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2003, Journal of neurochemistry.

A peptide that mimics the carboxy‐terminal domain of SNAP‐25 blocks Ca2+‐dependent exocytosis in chromaffin cells

J. Reig, A. Ferrer-Montiel, M. Montal, 1995, FEBS letters.

Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death

R. Houghten, S. Blondelle, E. Pérez-Payá, 1998, Nature Biotechnology.

Molecular design of the N-methyl-D-aspartate receptor binding site for phencyclidine and dizolcipine.

A. Ferrer-Montiel, M. Montal, W. Sun, 1995, Proceedings of the National Academy of Sciences of the United States of America.

TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Frontiers in molecular neuroscience.

Agonist- and Ca2+-dependent Desensitization of TRPV1 Channel Targets the Receptor to Lysosomes for Degradation*

A. Ferrer-Montiel, Amparo Andrés-Bordería, R. Planells-Cases, 2012, The Journal of Biological Chemistry.

GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization

A. Ferrer-Montiel, S. Laínez, P. Valente, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Androgenic TRPM8 activity drives sexual dimorphism in a murine model of chronic migraine

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2021 .

Pentameric subunit stoichiometry of a neuronal glutamate receptor.

A. Ferrer-Montiel, M. Montal, 1996, Proceedings of the National Academy of Sciences of the United States of America.

ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Pharmacology & therapeutics.

New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear β,γ-diamino ester scaffold

A. Fernández-Carvajal, A. Ferrer-Montiel, R. González-Muñiz, 2016 .

Membrane‐tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity

J. González-Ros, C. Belmonte, G. Fernández-Ballester, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain

E. Balazs, C. Belmonte, G. Fernández-Ballester, 2015, Nature Communications.

A single tryptophan on M2 of glutamate receptor channels confers high permeability to divalent cations.

A. Ferrer-Montiel, M. Montal, W. Sun, 1996, Biophysical journal.

1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A positive allosteric modulator of α7 nicotinic receptors with analgesic and neuroprotective activity.

F. Sala, A. Fernández-Carvajal, A. Ferrer-Montiel, 2019, ACS chemical neuroscience.

Comprehensive Survey of Consensus Docking for High-Throughput Virtual Screening

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Molecules.

TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Nature Communications.

Physiology and pharmacology of the vanilloid receptor.

Antonio Ferrer-Montiel, A. Ferrer-Montiel, A. Messeguer, 2006, Current neuropharmacology.

Salmonid viral haemorrhagic septicaemia virus: fusion-related enhancement of virus infectivity by peptides derived from viral glycoprotein G or a combinatorial library.

J. Encinar, E. Pérez-Payá, A. Ferrer-Montiel, 2002, The Journal of general virology.

A non-canonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression

G. Fernández-Ballester, A. Ferrer-Montiel, Ramón Martínez-Mármol, 2013, Journal of Cell Science.

Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity.

C. Belmonte, S. Ferroni, A. Fernández-Carvajal, 2006, The journal of pain : official journal of the American Pain Society.

Old Molecules for New Receptors: Trp(Nps) Dipeptide Derivatives as Vanilloid TRPV1 Channel Blockers

M. Bonache, A. Ferrer-Montiel, M. García-López, 2006, ChemMedChem.

Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds.

A. Ferrer-Montiel, A. Messeguer, C. García-Martínez, 2004, Journal of combinatorial chemistry.

Pharmacology of TRP Channels

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015 .

TRPV1 modulators: structure-activity relationships using a rational combinatorial approach.

F. Albericio, A. Ferrer-Montiel, M. García-López, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1.

F. Albericio, A. Fernández-Carvajal, A. Ferrer-Montiel, 2007, Journal of medicinal chemistry.

Drug design and development through the vanilloid receptor

A. Ferrer-Montiel, Rosa Planells-Cases1, 2007, Expert opinion on drug discovery.

Structural determinants of the blocker binding site in glutamate and NMDA receptor channels

A. Ferrer-Montiel, M. Montal, J. Merino, 1998, Neuropharmacology.

Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain

A. Ferrer-Montiel, J. McIntosh, M. Miras-Portugal, 2019, International journal of molecular sciences.

TRPC channels and diacylglycerol dependent calcium signaling in rat sensory neurons

A. Ferrer-Montiel, M. Kress, R. Haberberger, 2008, Histochemistry and Cell Biology.

The contribution of neurogenic inflammation to sensitive skin: concepts, mechanisms and cosmeceutical intervention

A. Ferrer-Montiel, P. Valente, M. Camprubí-Robles, 2009 .

Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger

R. Tsien, A. Ferrer-Montiel, M. Montal, 1999, Cell.

Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure.

F. Sala, L. M. Valor, L. Svobodová, 2014, European journal of medicinal chemistry.

Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells.

D. Klenerman, Y. Korchev, P. Anand, 2013, Analytical chemistry.

Primary structure, chromosomal localization, and functional expression of a voltage-gated sodium channel from human brain.

J. McPherson, A. F. Schinder, G. Evans, 1992, Proceedings of the National Academy of Sciences of the United States of America.

TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain

A. Ferrer-Montiel, Sara González-Rodríguez, Maite Artero-Morales, 2018, Front. Mol. Biosci..

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV‐1‐infected cells

P. Henklein, U. Schubert, A. Ferrer-Montiel, 1996, FEBS letters.

Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.

X. Xie, Yuanqiang Wang, G. Fernández-Ballester, 2019, ACS chemical neuroscience.

Possible coexistence of two independent mechanisms contributing to anthracycline resistance in leukaemia P388 cells.

J. González-Ros, S. Castanys, F. Gamarro, 1993, European journal of cancer.

Arginine‐rich peptides are blockers of VR‐1 channels with analgesic activity

J. González-Ros, E. Pérez-Payá, C. Belmonte, 2000, FEBS letters.

Identification of a Tetramerization Domain in the C Terminus of the Vanilloid Receptor

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2004, The Journal of Neuroscience.

Role of membrane lipids in the interaction of daunomycin with plasma membranes from tumor cells: implications in drug-resistance phenomena.

J. González-Ros, A. Ferrer-Montiel, J. Ferragut, 1990, Biochemistry.

Modulation of botulinum neurotoxin A catalytic domain stability by tyrosine phosphorylation

G. Fernández-Ballester, A. Ferrer-Montiel, C. Blanes-Mira, 2004, FEBS letters.

Regulated Exocytosis Contributes to Protein Kinase C Potentiation of Vanilloid Receptor Activity*

A. Ferrer-Montiel, C. Morenilla-Palao, R. Planells-Cases, 2004, Journal of Biological Chemistry.

Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2001, Biochemistry.

Structural stabilization of botulinum neurotoxins by tyrosine phosphorylation

J. González-Ros, J. Encinar, A. Ferrer-Montiel, 1998, FEBS letters.

Tyrosine Phosphorylation Modulates the Activity of Clostridial Neurotoxins*

A. Ferrer-Montiel, M. Montal, B. Dasgupta, 1996, The Journal of Biological Chemistry.

Identification of SNARE complex modulators that inhibit exocytosis from an alpha-helix-constrained combinatorial library.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2003, The Biochemical journal.

Acquisition of multidrug resistance by L1210 leukemia cells decreases their tumorigenicity and enhances their susceptibility to the host immune response

A. Ferrer-Montiel, P. García-Peñarrubia, J. Ferragut, 2005, Cancer Immunology, Immunotherapy.

Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.

A. F. Schinder, G. Evans, A. Ferrer-Montiel, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Calcium Entry Through Thermosensory Channels.

A. Ferrer-Montiel, I. Devesa, F. J. Taberner, 2016, Advances in experimental medicine and biology.

Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer.

Antonio Ferrer-Montiel, I. Gomez-Monterrey, A. Ferrer-Montiel, 2016, Journal of medicinal chemistry.

Trafficking of ThermoTRP Channels

A. Ferrer-Montiel, I. Devesa, Clotilde Ferrándiz-Huertas, 2014, Membranes.

Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties*

A. Ferrer-Montiel, J. Merino, C. García-Martínez, 2000, The Journal of Biological Chemistry.

Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification

G. Cavaletti, D. Lim, A. Fernández-Carvajal, 2020, International journal of molecular sciences.

The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating.

Beiying Liu, F. Qin, G. Fernández-Ballester, 2015, Biophysical journal.

Progress in the Structural Basis of thermoTRP Channel Polymodal Gating

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2023, International journal of molecular sciences.

Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation

J. González-Ros, G. Fernández-Ballester, A. Ferrer-Montiel, 2014, The Journal of general physiology.

Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I

C. Belmonte, G. Fernández-Ballester, A. Fernández-Carvajal, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2020, Expert opinion on investigational drugs.

Whirlin increases TRPV1 channel expression and cellular stability.

A. Ferrer-Montiel, P. Valente, N. Cuesta, 2016, Biochimica et biophysica acta.

TRP channels interaction with lipids and its implications in disease.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015, Biochimica et biophysica acta.

Advances in modulating thermosensory TRP channels

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2012, Expert opinion on therapeutic patents.

Triazine-based vanilloid 1 receptor open channel blockers: design, synthesis, evaluation, and SAR analysis.

J. González-Ros, A. Fernández-Carvajal, A. Ferrer-Montiel, 2011, Journal of medicinal chemistry.

Contribution of Ion Channel Trafficking to Nociceptor Sensitization

A. Ferrer-Montiel, M. Camprubí-Robles, R. Planells-Cases, 2010 .

Oligomerization of the Sensory and Motor Neuron-derived Factor Prevents Protein O-Glycosylation*

A. Ferrer-Montiel, H. Cabedo, Christelle Carteron, 2004, Journal of Biological Chemistry.

Different distribution of daunomycin in plasma membranes from drug-sensitive and drug-resistant P388 leukemia cells.

J. González-Ros, A. Ferrer-Montiel, J. Ferragut, 1992, Biochimica et biophysica acta.

Role of Membrane Components on Anthracycline Cytotoxicity

J. González-Ros, A. Ferrer-Montiel, J. Aleu, 1991 .

Ultrastructural alterations in plasma membranes from drug-resistant P388 murine leukemia cells.

J. González-Ros, L. Garcia-Segura, A. Ferrer-Montiel, 1990, Biochimica et biophysica acta.

Association of daunomycin to membrane domains studied by fluorescence resonance energy transfer.

J. González-Ros, A. Ferrer-Montiel, J. Ferragut, 1988, Biochimica et biophysica acta.

Ionic Channels as Targets for Drug Design: A Review on Computational Methods

Antonio Ferrer-Montiel, J. González-Ros, G. Fernández-Ballester, 2011, Pharmaceutics.

Identification of voltage-gated K(+) channel beta 2 (Kvβ2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1).

B. Sarg, H. Lindner, M. Langeslag, 2013, Biochimica et biophysica acta.

A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration.

J. Chun, A. Ferrer-Montiel, R. Rivera, 2019, Journal of medicinal chemistry.

Estrogen destabilizes microtubules through an ion‐conductivity‐independent TRPV1 pathway

G. Fernández-Ballester, A. Ferrer-Montiel, C. Goswami, 2011, Journal of neurochemistry.

Lipids as central modulators of sensory TRP channels.

A. Ferrer-Montiel, M. Ciardo, 2017, Biochimica et biophysica acta. Biomembranes.

1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties.

F. Sala, Beatriz Balsera, A. Fernández-Carvajal, 2016, Future medicinal chemistry.

Agonist-independent activation of acetylcholine receptor channels by protein kinase A phosphorylation.

M. Montal, A. Ferrer-Montiel, M. Díaz-Muñoz, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Role of the transient receptor potential vanilloid 1 in inflammation and sepsis

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2011, Journal of inflammation research.

Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia

A. Ferrer-Montiel, C. Morenilla-Palao, R. Planells-Cases, 2005, Pflügers Archiv.

Structural and in Vitro Functional Characterization of a Menthyl TRPM8 Antagonist Indicates Species-Dependent Regulation.

X. Xie, Yuanqiang Wang, A. Fernández-Carvajal, 2021, ACS medicinal chemistry letters.

Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity.

Ettore Novellino, Simona Musella, Nunzio Iraci, 2018, Journal of medicinal chemistry.

New Strategies to Develop Novel Pain Therapies: Addressing Thermoreceptors from Different Points of View

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2011, Pharmaceuticals.

TRPA1 modulators in preclinical development

A. Ferrer-Montiel, F. Viana, 2009, Expert opinion on therapeutic patents.

Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels

G. Fernández-Ballester, A. Ferrer-Montiel, F. Viana, 2009, Molecular pain.

Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors

J. Changeux, A. Ferrer-Montiel, I. Devesa, 2016, Front. Pharmacol..

A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity.

V. Felipo, E. Pérez-Payá, C. Montoliu, 2002, The Journal of pharmacology and experimental therapeutics.

DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target.

M. Martín-Martínez, O. Abián, A. Velázquez‐Campoy, 2021, Bioorganic chemistry.

αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors

J. Changeux, R. Luján, A. Ferrer-Montiel, 2014, Proceedings of the National Academy of Sciences.

Differential contribution of SNARE‐dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors

A. Ferrer-Montiel, M. Camprubí-Robles, R. Planells-Cases, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity

G. Fernández-Ballester, I. Gomez-Monterrey, M. Bonache, 2021, International journal of molecular sciences.

Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity

G. Fernández-Ballester, M. Bonache, A. Fernández-Carvajal, 2020, Scientific Reports.

NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway

A. Ferrer-Montiel, A. Messeguer, J. Merino, 2008, Neurochemistry International.

Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants.

J. Canales, V. Felipo, F. Sánchez-Baeza, 2002, The Journal of pharmacology and experimental therapeutics.

Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons

A. Ferrer-Montiel, A. Messeguer, P. Fernández-Salguero, 2002, Neuromolecular medicine.

The calmodulin‐binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3

G. Fernández-Ballester, A. Ferrer-Montiel, M. Tamkun, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

An Inhibitor of Neuronal Exocytosis (DD04107) Displays Long-Lasting In Vivo Activity against Chronic Inflammatory and Neuropathic Pain

V. Felipo, A. Ferrer-Montiel, O. Cauli, 2012, Journal of Pharmacology and Experimental Therapeutics.

Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention.

F. Qin, A. Ferrer-Montiel, A. Szallasi, 2011, Advances in experimental medicine and biology.

A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability

A. Fernández-Carvajal, A. Ferrer-Montiel, T. Pirali, 2021, Scientific reports.

A Role of the Transient Receptor Potential Domain of Vanilloid Receptor I in Channel Gating

C. Belmonte, G. Fernández-Ballester, A. Fernández-Carvajal, 2007, The Journal of Neuroscience.

Small molecules targeting the vanilloid receptor complex as drugs for inflammatory pain

E. Pérez-Payá, F. Albericio, A. Ferrer-Montiel, 2003 .

Peptide Revolution: Genomics, Proteomics & Therapeutics

F. Albericio, A. Ferrer-Montiel, R. González-Muñiz, 2004 .

Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes

L. M. Valor, A. Ferrer-Montiel, A. Barco, 2016, Neurobiology of Disease.

A Peptide That Mimics the C-terminal Sequence of SNAP-25 Inhibits Secretory Vesicle Docking in Chromaffin Cells*

A. Ferrer-Montiel, M. Montal, S. Viniegra, 1997, The Journal of Biological Chemistry.

Benzydamine inhibits neuronal excitability induced by inflammatory mediators to relieve pain

A. Ferrer-Montiel, G. Mangano, L. Polenzani, 2022, Biophysical Journal.

Molecular architecture of the vanilloid receptor. Insights for drug design.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2004, European journal of biochemistry.

Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.

E. Novellino, A. Bertamino, I. Gomez-Monterrey, 2016, Journal of medicinal chemistry.

Design and validation of neuronal exocytosis blocking peptides as potential novel antiperspirants

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2023, Experimental dermatology.

Structural Compatibility between the Putative Voltage Sensor of Voltage-gated K+ Channels and the Prokaryotic KcsA Channel*

S. Ferroni, A. Ferrer-Montiel, M. Montal, 2001, The Journal of Biological Chemistry.

Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.

A. Ferrer-Montiel, W. Sun, M. Montal, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Structure-Function Relations in Ligand-Gated Ion Channels: Reconstitution in Lipid Bilayers and Heterologous Expression in Xenopus Oocytes

A. Ferrer-Montiel, M. Montal, 1994 .

Ion binding to KcsA: implications in ion selectivity and channel gating.

J. Encinar, A. Ferrer-Montiel, A. Fernández, 2010, Biochemistry.

Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability.

J. González-Ros, J. Encinar, G. Fernández-Ballester, 2012, Biochemistry.

Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity.

L. Naesens, F. Sala, Beatriz Balsera, 2018, European journal of medicinal chemistry.

Pharmacological intervention at ionotropic glutamate receptor complexes.

Juan Lerma, Antonio Ferrer-Montiel, A. Ferrer-Montiel, 2006, Current pharmaceutical design.

Effect of econazole and benzydamine on sensory neurons in culture.

A. Ferrer-Montiel, G. Mangano, L. Polenzani, 2016, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating.

A. Ferrer-Montiel, M. Montal, R. Planells-Cases, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved.

J. González-Ros, J. Encinar, A. Ferrer-Montiel, 2013, Biochimica et biophysica acta.

Primary structure and functional expression of the AMPA/kainate receptor subunit 2 from human brain.

A. Ferrer-Montiel, M. Montal, W. Sun, 1994, Neuroreport.

Insights for drug design

A. Ferrer-Montiel, C. Morenilla-Palao, R. Planells-Cases, 2004 .

TRP Channels

C. Montell, A. Ferrer-Montiel, K. Venkatachalam, 2019, Methods in Molecular Biology.

Reconstitution of Channel Proteins from Excitable Cells in Lipid Bilayers: Authentic and Designed Proteins

A. Ferrer-Montiel, M. Montal, A. Grove, 1994 .

The Region Adjacent to the C-end of the Inner Gate in Transient Receptor Potential Melastatin 8 (TRPM8) Channels Plays a Central Role in Allosteric Channel Activation*

Y. Korchev, G. Fernández-Ballester, A. Ferrer-Montiel, 2014, The Journal of Biological Chemistry.

Design of bioactive and structurally well‐defined peptides from conformationally restricted libraries

E. Pérez-Payá, A. Ferrer-Montiel, Puig Mora, 2004, Biopolymers.

ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Pharmacology and Therapeutics.

NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway

A. Ferrer-Montiel, A. Messeguer, J. Merino, 2008, Neurochemistry International.

Identification of voltage-gated K(+) channel beta 2 (Kvβ2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1).

B. Sarg, H. Lindner, M. Langeslag, 2013, Biochimica et biophysica acta.

Advances in modulating thermosensory TRP channels

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2012, Expert opinion on therapeutic patents.

Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention.

F. Qin, A. Ferrer-Montiel, A. Szallasi, 2011, Advances in experimental medicine and biology.

TRP channels interaction with lipids and its implications in disease.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015, Biochimica et biophysica acta.

The Surface Charge of Membranes Modulates the Interaction with the Anthracycline Daunomycin a

J. González-Ros, A. Ferrer-Montiel, J. Ferragut, 1988, Annals of the New York Academy of Sciences.

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators.

M. Martín-Martínez, I. Gomez-Monterrey, M. Bonache, 2014, ACS combinatorial science.

Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved.

J. González-Ros, J. Encinar, A. Ferrer-Montiel, 2013, Biochimica et Biophysica Acta.

Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein.

J. González-Ros, J. Encinar, D. Otzen, 2010, Biochemistry.

Synthesis, high-throughput screening and pharmacological characterization of β–lactam derivatives as TRPM8 antagonists

G. Fernández-Ballester, M. Bonache, Beatriz Balsera, 2017, Scientific Reports.

Targeting protein–protein interactions to rescue Δf508-cftr: a novel corrector approach to treat cystic fibrosis

Antonio Ferrer-Montiel, G. Fernández-Ballester, A. Ferrer-Montiel, 2013, EMBO molecular medicine.

Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.

A. Fernández-Carvajal, A. Ferrer-Montiel, G. Sorba, 2018, Journal of medicinal chemistry.

β-Lactam TRPM8 Antagonists Derived from Phe-Phenylalaninol Conjugates: Structure–Activity Relationships and Antiallodynic Activity

G. Fernández-Ballester, M. Bonache, A. Fernández-Carvajal, 2023, International journal of molecular sciences.