D. Carnathan

发表

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

S. Christley, John P. Moore, D. Burton, 2020, bioRxiv.

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

S. Christley, John P. Moore, D. Burton, 2020, PLoS pathogens.

S. Sugden, D. Hazuda, F. Pereyra, 2012, Journal of the International AIDS Society.

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

Bali Pulendran, Guido Silvestri, B. Pulendran, 2016, The Journal of Immunology.

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

Daniel W. Kulp, D. Irvine, D. Burton, 2018, Cell.

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

D. Baker, D. Irvine, N. King, 2020, npj Vaccines.

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

D. Irvine, David Baker, N. King, 2020, npj Vaccines.

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

D. Irvine, D. Burton, D. Montefiori, 2021, bioRxiv.

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

Daniel W. Kulp, D. Irvine, R. Wyatt, 2017, Immunity.

Dendritic cell regulation of B cells

D. Carnathan, 2007 .

Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques

Andrew P. Hodges, A. Godzik, D. Burton, 2016, AIDS.

B-Lymphocyte Dysfunction in Chronic HIV-1 Infection Does Not Prevent Cross-Clade Neutralization Breadth

C. A. Derdeyn, D. Carnathan, G. Silvestri, 2012, Journal of Virology.

Resource Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches Graphical Abstract Highlights

Daniel W. Kulp, D. Irvine, R. Wyatt, 2022 .

An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model

V. Nizet, J. McCarthy, M. Davies, 2019, mBio.

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

D. Baker, John P. Moore, D. Burton, 2021, Nature Communications.

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2

Neil C. Dalvie, J. C. Love, Sergio A. Rodriguez-Aponte, 2021, Science advances.

The contribution of non-human primate models to the development of human vaccines.

D. Carnathan, G. Silvestri, I. Toth, 2014, Discovery medicine.

CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques

A. Perelson, J. Lifson, R. Ke, 2021 .

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity

D. Irvine, D. Burton, A. Belcher, 2021, Science Immunology.

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

D. Burton, R. Ahmed, A. Ward, 2020, Frontiers in Immunology.

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys

J. Brenchley, M. Davenport, D. Carnathan, 2016, PloS one.

From Structure to Sequence: Identification of polyclonal antibody families using cryoEM

W. Schief, A. Ward, S. Crotty, 2021, bioRxiv.

Long-primed germinal centres with enduring affinity maturation and clonal migration

D. Irvine, D. Burton, D. Montefiori, 2022, Nature.

Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model

M. Betts, M. Connell, James M. Wilson, 2019, Pathogens & immunity.

Vaccination with Ad5 Vectors Expands Ad5-Specific CD8+ T Cells without Altering Memory Phenotype or Functionality

M. Betts, H. Ertl, D. Carnathan, 2010, PloS one.

Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys: Implications for AIDS Pathogenesis

J. Lifson, B. Keele, D. Carnathan, 2016, Journal of Virology.

Generation of antigen-specific immunity following systemic immunization with DNA vaccine encoding CCL25 chemokine immunoadjuvant

D. Weiner, M. Kutzler, M. Betts, 2012, Human vaccines & immunotherapeutics.

Dendritic Cells from Lupus-Prone Mice Are Defective in Repressing Immunoglobulin Secretion1

D. Carnathan, A. Baldwin, B. Vilen, 2007, The Journal of Immunology.

Defective in Repressing Immunoglobulin Dendritic Cells from Lupus-Prone Mice Are

D. Carnathan, A. Baldwin, B. Vilen, 2007 .

Secretion Defective in Repressing Immunoglobulin Dendritic Cells from Lupus-Prone Mice Are

D. Carnathan, A. Baldwin, B. Vilen, 2007 .

Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive.

M. Betts, H. Ertl, D. Carnathan, 2010, Vaccine.

Target Cell Availability, Rather than Breast Milk Factors, Dictates Mother-to-Infant Transmission of SIV in Sooty Mangabeys and Rhesus Macaques

R. Swanstrom, C. A. Derdeyn, D. Carnathan, 2014, PLoS pathogens.

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

D. Carnathan, G. Silvestri, M. Paiardini, 2021, PLoS pathogens.

Chemokine Adjuvanted Electroporated-DNA Vaccine Induces Substantial Protection from Simian Immunodeficiency Virus Vaginal Challenge

N. Sardesai, D. Weiner, M. Kutzler, 2015, Mucosal Immunology.

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

Daniel W. Kulp, D. Irvine, D. Burton, 2018, Cell.

Baseline Ad5 serostatus does not predict Ad5-HIV vaccine-induced expansion of Ad-specific CD4+ T-cells

M. Betts, H. Ertl, D. Carnathan, 2009, Nature Medicine.

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques

M. Betts, G. Shaw, Hui Li, 2016, PLoS pathogens.

CD8+ lymphocytes do not impact SIV reservoir establishment under ART

Hong Wang, J. Siliciano, C. Fennessey, 2023, Nature Microbiology.

CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques

A. Perelson, J. Lifson, N. Schoof, 2021, Journal of Virology.

Short-Term Pegylated Interferon α2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques

J. Billingsley, D. Carnathan, G. Silvestri, 2018, Journal of Virology.

Short-term pIFN-α 2 a treatment does not significantly reduce the viral reservoir of 1 SIV-infected , ART-treated rhesus macaques 2 3

J. Billingsley, D. Carnathan, G. Silvestri, 2018 .

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

J. Safrit, J. Lifson, D. Margolis, 2020, Nature.

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization

D. Irvine, D. Burton, W. Schief, 2019, Cell reports.

Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates.

D. Irvine, W. Schief, Wei Zhang, 2021, Biomaterials.

Intragastric Administration of Lactobacillus plantarum and 2,2′-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission

W. Lu, D. Carnathan, G. Silvestri, 2018, Journal of Virology.

Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques

J. Safrit, D. Carnathan, G. Silvestri, 2020, Journal of Virology.

Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors

J. Billingsley, Z. Xiang, H. Ertl, 2018, EBioMedicine.

Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

N. Sardesai, D. Weiner, Jian Yan, 2014, Proceedings of the National Academy of Sciences.

with Repeated Low Doses of SIVmac Fusion Protein and Challenged Intrarectally Simian Immunodeficiency Virus Gag/Tat Chimpanzee Adenoviruses Expressing the Rhesus Macaques Immunized with Immunological and Virological Analyses of

H. Ertl, D. Carnathan, M. Paiardini, 2014 .

Immunological and Virological Analyses of Rhesus Macaques Immunized with Chimpanzee Adenoviruses Expressing the Simian Immunodeficiency Virus Gag/Tat Fusion Protein and Challenged Intrarectally with Repeated Low Doses of SIVmac

H. Ertl, D. Carnathan, G. Silvestri, 2013, Journal of Virology.

Increased Mucosal CD4+ T Cell Activation in Rhesus Macaques following Vaccination with an Adenoviral Vector

M. Betts, James M. Wilson, S. Bellamy, 2014, Journal of Virology.

Longitudinally Tracked, Rapid and Robust Antigen-Specific Germinal Center Responses in Non-Human Primates after a Single Nanoparticle Vaccine Immunization

D. Irvine, D. Burton, W. Schief, 2019, SSRN Electronic Journal.

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.

Jennifer S. Wood, B. Pulendran, John P. Moore, 2016, Cell reports.

From structure to sequence: Antibody discovery using cryoEM

W. Schief, A. Ward, S. Crotty, 2022, Science advances.

Long-primed germinal centres with enduring affinity maturation and clonal migration

D. Irvine, D. Burton, D. Montefiori, 2022, Nature.

Corrigendum: Baseline Ad5 serostatus does not predict Ad5 HIV vaccine–induced expansion of adenovirus-specific CD4+ T cells

M. Betts, H. Ertl, D. Carnathan, 2009, Nature Medicine.

Antibody-Mediated CD4 Depletion Induces Homeostatic CD4+ T Cell Proliferation without Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques

D. Carnathan, G. Silvestri, M. Paiardini, 2018, Journal of Virology.

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Cynthia A. Derdeyn, Deanna A. Kulpa, Guido Silvestri, 2020, Nature.

Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques

J. Billingsley, R. Sékaly, M. Cameron, 2018, Journal of Virology.

Focusing antibody responses to the fusion peptide in rhesus macaques

D. Irvine, D. Burton, D. Montefiori, 2023, bioRxiv.

Chemokine Adjuvanted Electroporated-DNA Vaccine Induces Substantial Protection from Simian Immunodeficiency Virus Vaginal Challenge

N. Sardesai, D. Weiner, M. Kutzler, 2015, Mucosal Immunology.

Correlates of relative resistance against low‐dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques

D. Carnathan, G. Silvestri, A. Kossenkov, 2013, Journal of leukocyte biology.