W. Mothes

发表

An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity.

James B. Munro, J. Sodroski, D. Kaufmann, 2019, Cell host & microbe.

Crystal structure , conformational fixation , and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016 .

TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling

P. Uchil, J. Luban, W. Mothes, 2015, Journal of Virology.

HIV Entry Revisited

Walther Mothes, Pradeep D. Uchil, P. Uchil, 2009, Cell.

Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells

Nathan M. Sherer, Walther Mothes, W. Mothes, 2005, The Journal of cell biology.

Native structure of a retroviral envelope protein and its conformational change upon interaction with the target cell

D. Vasishtan, K. Grünewald, C. A. Siebert, 2017, Journal of structural biology.

Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission

W. Mothes, N. Sherer, M. Lehmann, 2007, Nature Cell Biology.

TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle

P. Uchil, Wai-Tsing Chan, W. Mothes, 2008, PLoS pathogens.

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF-κB-Responsive Long Terminal Repeat Elements

P. Uchil, J. Luban, A. Kajaste-Rudnitski, 2011, Journal of Virology.

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Jeremy Luban, Caterina Strambio-De-Castillia, Walther Mothes, 2011, Nature.

Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, Immunity.

Murine Leukemia Virus Gag Localizes to the Uropod of Migrating Primary Lymphocytes

Fei Li, W. Mothes, N. Sherer, 2014, Journal of Virology.

Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

Shijian Zhang, H. Ding, J. Kappes, 2020, Journal of Virology.

Attachment of cell-binding ligands to arginine-rich cell-penetrating peptides enables cytosolic translocation of complexed siRNA.

P. Uchil, T. Fahmy, W. Mothes, 2015, Chemistry & biology.

Viruses exploit the tissue physiology of the host to spread in vivo.

W. Mothes, Nasim Motamedi, Xaver Sewald, 2016, Current opinion in cell biology.

TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

P. Uchil, J. Luban, W. Mothes, 2012, Journal of Virology.

Secreted cathepsin L generates endostatin from collagen XVIII

H. Ploegh, U. Felbor, R. Bryant, 2000, The EMBO journal.

Signal Sequence Recognition in Cotranslational Translocation by Protein Components of the Endoplasmic Reticulum Membrane

B. Jungnickel, T. Rapoport, W. Mothes, 1998, The Journal of cell biology.

In vivo Imaging-Driven Approaches to Study Virus Dissemination and Pathogenesis.

P. Uchil, W. Mothes, Kelsey A. Haugh, 2019, Annual review of virology.

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

M. Pazgier, C. Abrams, J. Richard, 2021, bioRxiv.

Ca2+ and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes

Steven M. Becker, W. Mothes, C. Czibener, 2006, The Journal of cell biology.

Retroviruses Human Immunodeficiency Virus and Murine Leukemia Virus Are Enriched in Phosphoinositides

P. Uchil, W. Mothes, M. Wenk, 2008, Journal of Virology.

Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity

W. Mothes, J. Stoye, G. Kassiotis, 2017, Journal of Virology.

A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

P. Uchil, P. Bjorkman, M. Santiago, 2019, Cell host & microbe.

CryoEM Structures of the Human HIV-1 Restriction Factor SERINC3 and Function as a Lipid Transporter

M. Yeager, P. Uchil, S. Erramilli, 2022, bioRxiv.

VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry

D. Vézina, P. Uchil, C. Baron, 2022, iScience.

Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

L. Stamatatos, D. Kaufmann, P. Uchil, 2021, bioRxiv.

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

Hidde L. Ploegh, Bjorn R. Olsen, Hans H. Goebel, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2022, Science advances.

NF-κB-Chromatin Interactions Drive Diverse Phenotypes by Modulating Transcriptional Noise.

Robin E. C. Lee, S. Gaudet, Arvind K. Chavali, 2018, Cell reports.

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

T. Rapoport, M. Bogyo, H. Ploegh, 1996, Nature.

Molecular basis for antiviral activity of pediatric neutralizing antibodies targeting SARS-CoV-2 Spike receptor binding domain

D. Vézina, E. Haddad, P. Uchil, 2022, bioRxiv.

Viral Determinants of Polarized Assembly for the Murine Leukemia Virus

W. Mothes, Jing Jin, Fei Li, 2011, Journal of Virology.

Directional Spread of Surface-Associated Retroviruses Regulated by Differential Virus-Cell Interactions

W. Mothes, N. Sherer, Jing Jin, 2010, Journal of Virology.

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3-Ubiquitin Ligase 1

J. Luban, A. Kajaste-Rudnitski, W. Mothes, 2011 .

SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release

D. DiMaio, W. Mothes, Nasim Motamedi, 2018, bioRxiv.

The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

P. Uchil, W. Mothes, A. Finzi, 2022, bioRxiv.

Cancer Microbiology.

D. DiMaio, W. Mothes, A. Goodman, 2021, Journal of the National Cancer Institute.

In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission

P. Uchil, P. Bjorkman, W. Mothes, 2020, bioRxiv.

The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeﬁciency Virus Infection (cid:1)

W. Greene, F. Kirchhoff, K. Smith-McCune, 2008 .

Human TRIM Gene Expression in Response to Interferons

A. Bergamaschi, P. Uchil, S. Nisole, 2009, PloS one.

Asymmetric HIV-1 envelope trimers bound to one and two CD4 molecules are intermediates during membrane binding

H. Tagare, J. Lifson, P. Uchil, 2022, bioRxiv.

Structure and dynamics of the native HIV-1 Env trimer 2

James B. Munro, W. Mothes, 2015 .

The HIV-1 Env trimer in HD.

James B. Munro, W. Mothes, 2014, Structure.

Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env

M. Pazgier, W. Tolbert, J. Richard, 2019, Journal of Virology.

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

D. Vézina, E. Haddad, P. Uchil, 2022, iScience.

Proteomic analysis of cathepsin B and L-deficient mouse brain lysosomes

U. Felbor, A. Sickmann, W. Mothes, 2007, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.

Cell-to-Cell Transmission Can Overcome Multiple Donor and Target Cell Barriers Imposed on Cell-Free HIV

P. Uchil, W. Mothes, G. Heidecker, 2013, PloS one.

Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis.

Nathan M Sherer, Walther Mothes, W. Mothes, 2008, Trends in cell biology.

The Mature Avian Leukosis Virus Subgroup A Envelope Glycoprotein Is Metastable, and Refolding Induced by the Synergistic Effects of Receptor Binding and Low pH Is Coupled to Infection

S. Blacklow, J. Cunningham, Jason G. Smith, 2004, Journal of Virology.

Retroviral Entry Mediated by Receptor Priming and Low pH Triggering of an Envelope Glycoprotein

J. Cunningham, J. Young, W. Mothes, 2000, Cell.

Assembly of the Murine Leukemia Virus Is Directed towards Sites of Cell–Cell Contact

W. Mothes, G. Heidecker, N. Sherer, 2009, PLoS biology.

Imaging individual retroviral fusion events: from hemifusion to pore formation and growth.

J. Young, W. Mothes, G. Melikyan, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Proceedings of the Frontiers of Retrovirology Conference 2016

R. König, D. Elleder, R. Sachidanandam, 2016, Retrovirology.

Signal Sequence Recognition in Posttranslational Protein Transport across the Yeast ER Membrane

B. Wilkinson, T. Rapoport, K. Plath, 1998, Cell.

The Sec61p Complex Mediates the Integration of a Membrane Protein by Allowing Lipid Partitioning of the Transmembrane Domain

T. Rapoport, W. Mothes, J. Brunner, 2000, Cell.

Molecular Mechanism of Membrane Protein Integration into the Endoplasmic Reticulum

T. Rapoport, G. Heijne, I. Nilsson, 1997, Cell.

Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection

F. Kirchhoff, D. Fowler, J. Kelly, 2007, Cell.

Functional Characterization of the Putative Hepatitis B Virus Core Protein Late Domain Using Retrovirus Chimeras

W. Mothes, M. Robek, T. D. Reynolds, 2013, PloS one.

Visualization of Retroviral Replication in Living Cells Reveals Budding into Multivesicular Bodies

J. Cunningham, W. Mothes, N. Sherer, 2003, Traffic.

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

P. Uchil, P. Bjorkman, W. Mothes, 2015, Science.

HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy.

Walther Mothes, P. Uchil, W. Mothes, 2015, Trends in microbiology.

Cell-to-cell transmission of viruses.

James B. Munro, Walther Mothes, W. Mothes, 2013, Current opinion in virology.

Virus Cell-to-Cell Transmission

Nathan M. Sherer, Walther Mothes, W. Mothes, 2010, Journal of Virology.

Cell-to-Cell Transmission of HIV

W. Mothes, L. Agosto, Peng Zhong, 2013 .

HIV-1 Matrix Dependent Membrane Targeting Is Regulated by Gag mRNA Trafficking

T. Sturgeon, W. Mothes, O. Weisz, 2009, PloS one.

Protein Translocation: Tunnel Vision

T. Rapoport, W. Mothes, K. Matlack, 1998, Cell.

TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly

James B. Munro, P. Uchil, J. Bewersdorf, 2014, Journal of Cell Science.

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

C. Soto, T. Lemmin, Cinque S. Soto, 2016, Science.

Video-rate nanoscopy enabled by sCMOS camera-specific single-molecule localization algorithms

Michael W. Davidson, Yu Lin, Derek Toomre, 2013, Nature Methods.

A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses

D. Vézina, L. Stamatatos, V. Martel-Laferrière, 2021, Cell Host & Microbe.

Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2

M. Pazgier, C. Abrams, J. Richard, 2021, Journal of Biological Chemistry.

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

Daniel S. Terry, J. Lifson, Baoshan Zhang, 2020, Nature Structural & Molecular Biology.

Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2

J. Mascola, G. Chuang, Y. Lai, 2022, The Journal of biological chemistry.

Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands

Daniel S. Terry, J. Sodroski, S. Blanchard, 2020, Journal of Virology.

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Peter D. Kwong, Joel R. Courter, Dennis R. Burton, 2014, Science.

Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, Cell Reports.

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

James B. Munro, Daniel S. Terry, Luis R. Castillo-Menendez, 2019, Nature.

Structure and immune recognition of trimeric prefusion HIV-1 Env

Tongqing Zhou, Yongping Yang, Baoshan Zhang, 2014, Nature.

HIV-1-Infected CD4+ T Cells Facilitate Latent Infection of Resting CD4+ T Cells through Cell-Cell Contact.

W. Mothes, L. Agosto, A. Henderson, 2018, Cell reports.

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

D. Vézina, Shijian Zhang, J. Sodroski, 2021, bioRxiv.

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

Daniel S. Terry, D. Ho, J. Mascola, 2020, bioRxiv.

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

Daniel S. Terry, D. Ho, J. Mascola, 2020, Cell Host & Microbe.

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

A. Bartesaghi, M. Borgnia, B. Haynes, 2019, Nature Communications.

Illuminating the virus life cycle with single-molecule FRET imaging.

W. Mothes, Xiaochu Ma, Maolin Lu, 2019, Advances in virus research.

Basic Residues in the Matrix Domain and Multimerization Target Murine Leukemia Virus Gag to the Virological Synapse

Fei Li, W. Mothes, Jing Jin, 2013, Journal of Virology.

CryoEM Structures of the Human HIV-1 Restriction Factor SERINC3 and Function as a Lipid Transporter

M. Yeager, P. Uchil, S. Erramilli, 2022, bioRxiv.

SARS-CoV-2 Variants Increase Kinetic Stability of Open Spike Conformations as an Evolutionary Strategy

T. Zhou, P. Kwong, Shilei Ding, 2022, mBio.

A Conformational Transition Observed in Single HIV-1 Gag Molecules during In Vitro Assembly of Virus-Like Particles

James B. Munro, W. Mothes, A. Rein, 2014, Journal of Virology.

Structure and Dynamics of the Native HIV-1 Env Trimer

James B. Munro, W. Mothes, 2015, Journal of Virology.

Highly Active Antiretroviral Therapies Are Effective against HIV-1 Cell-to-Cell Transmission

James B. Munro, W. Mothes, L. Agosto, 2014, PLoS pathogens.

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

D. Vézina, L. Stamatatos, V. Martel-Laferrière, 2021, bioRxiv.

Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120.

D. Kaufmann, M. Pazgier, W. Tolbert, 2023, Cell chemical biology.

The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection

W. Greene, F. Kirchhoff, K. Smith-McCune, 2008, Journal of Virology.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2021, bioRxiv.

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

D. Vézina, L. Stamatatos, P. Uchil, 2022, Cell Reports.

Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane.

T. Rapoport, W. Mothes, S. Prehn, 1994, The EMBO journal.

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

James B. Munro, Daniel S. Terry, P. Kwong, 2018, eLife.

SARS-CoV-2 variants exhibit increased kinetic stability of open spike conformations as an evolutionary strategy

Shilei Ding, W. Mothes, A. Finzi, 2021, bioRxiv.

Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice

A. Iwasaki, P. Uchil, W. Mothes, 2019, Journal of Virology.

The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

Alon Herschhorn, Christopher Gu, J. Sodroski, 2017, Nature Communications.

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins

James B. Munro, Daniel S. Terry, Alon Herschhorn, 2016, mBio.

VE607 Stabilizes SARS-CoV-2 Spike In the “RBD-up” Conformation and Inhibits Viral Entry

D. Vézina, C. Baron, M. Pazgier, 2022, bioRxiv.

Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice

P. Uchil, G. Gendron-Lepage, W. Mothes, 2023, bioRxiv.

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

D. Vézina, L. Stamatatos, P. Uchil, 2021, bioRxiv.

In vivo imaging of virological synapses

Walther Mothes, W. Mothes, A. Haberman, 2012, Nature Communications.

Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models

P. Uchil, E. Fikrig, W. Mothes, 2023, Vaccines.

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

James B. Munro, Daniel S. Terry, Luis R. Castillo-Menendez, 2019, Nature.

A Biocontainment Procedure for Intravital Microscopy of High-Risk Pathogens

P. Uchil, W. Mothes, Benjamin Fontes, 2018, Applied Biosafety.

Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice

T. Hope, P. Uchil, W. Mothes, 2019, bioRxiv.

Proceedings of the Frontiers of Retrovirology Conference 2016

Sebastian A. Wagner, R. König, D. Elleder, 2016, Retrovirology.

Murine Leukemia Virus Spreading in Mice Impaired in the Biogenesis of Secretory Lysosomes and Ca2+-Regulated Exocytosis

P. Uchil, Wai-Tsing Chan, W. Mothes, 2008, PloS one.

Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry

M. Yeager, P. Uchil, S. Erramilli, 2023, Nature communications.

Protein Translocation: Review Tunnel Vision

T. Rapoport, W. Mothes, K. Matlack, 1998 .

Scholar Works at UT Tyler Scholar Works at UT Tyler

T. Zhou, P. Kwong, W. Mothes, 2023 .

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

P. Uchil, J. Bewersdorf, C. Wilen, 2023, Nature.

Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine

M. Bolognesi, P. Uchil, G. Grandi, 2021, bioRxiv.

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

James B. Munro, Daniel S. Terry, Cinque S. Soto, 2015, Nature Structural &Molecular Biology.

Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

Alon Herschhorn, Christopher Gu, J. Sodroski, 2018, Nature Communications.

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

P. Uchil, M. Pazgier, G. Piszczek, 2022, Science advances.

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF- (cid:1) B-Responsive Long Terminal Repeat Elements (cid:1)

P. Uchil, A. Kajaste-Rudnitski, W. Mothes, 2011 .

Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells

W. Mothes, N. Sherer, M. Lehmann, 2005, The Journal of cell biology.

Directional Spread of Surface-Associated Retroviruses Regulated by Differential Virus-Cell Interactions

W. Mothes, N. Sherer, Jing Jin, 2010, Journal of Virology.

Surface Transmission or Polarized Egress? Lessons Learned from HTLV Cell-to-Cell Transmission

W. Mothes, N. Sherer, Jing Jin, 2010, Viruses.

HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy.

P. Uchil, W. Mothes, L. Agosto, 2015, Trends in microbiology.

Ca2+ and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes

Steven M. Becker, W. Mothes, C. Czibener, 2006, The Journal of cell biology.

HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes

H. Tagare, J. Lifson, P. Uchil, 2023, Nature.

Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens

P. Uchil, G. Gendron-Lepage, W. Mothes, 2024, iScience.

Proof-of-concept studies with a computationally designed Mpro inhibitor as a synergistic combination regimen alternative to Paxlovid

P. Uchil, W. Mothes, K. Spasov, 2024, Proceedings of the National Academy of Sciences of the United States of America.

Epistatic pathways can drive HIV-1 escape from integrase strand transfer inhibitors

W. Mothes, Jonathan R. Grover, Eric O. Freed, 2024, Science advances.

Single-Molecule FRET Delineates Asymmetric Trimer Conformations during HIV-1 Entry

James B. Munro, Daniel S. Terry, P. Kwong, 2017 .

Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging.

J. Arthos, W. Mothes, G. Melikyan, 2024, Cell chemical biology.

A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

P. Uchil, P. Bjorkman, M. Santiago, 2019, Cell host & microbe.

Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia

C. Chartrand-Lefebvre, M. Pazgier, W. Tolbert, 2023, The Journal of infectious diseases.