Adrian W Hodel

发表

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

J. Whisstock, B. Hoogenboom, S. Pang, 2019, Nature Communications.

Wedged AFM-cantilevers for parallel plate cell mechanics.

Daniel J Müller, Jonne Helenius, D. Müller, 2013, Methods.

Atomic force microscopy of membrane pore formation by cholesterol dependent cytolysins.

H. Saibil, B. Hoogenboom, Adrian W Hodel, 2016, Current opinion in structural biology.

Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Maya Topf, Helen R Saibil, Cyril F. Reboul, 2014, eLife.

Lipid order and charge protect killer T cells from accidental death

J. Trapani, B. Hoogenboom, Adrian W Hodel, 2019, Nature Communications.

Single-molecule kinetics of pore assembly by the membrane attack complex

G. Stanley, B. Hoogenboom, G. Fantner, 2018, Nature Communications.

Real-time visualization of perforin nanopore assembly.

J. Whisstock, H. Saibil, J. Trapani, 2017, Nature nanotechnology.

The structure of Macrophage Expressed Gene-1, a phagolysosome immune effector that is activated upon acidification

J. Whisstock, B. Hoogenboom, S. Pang, 2019, bioRxiv.

Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick Syndrome type C1.

J. Trapani, A. Brennan, M. Walterfang, 2022, Blood.

Lipid specificity of the immune effector perforin

J. Trapani, B. Hoogenboom, Adrian W Hodel, 2020, bioRxiv.

AFM imaging of pore forming proteins.

B. Hoogenboom, Adrian W Hodel, K. Hammond, 2021, Methods in enzymology.

Acidic pH attenuates immune killing through inactivation of perforin

B. Hoogenboom, Adrian W Hodel, I. Voskoboinik, 2024, bioRxiv.

Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells

J. Trapani, Adrian W Hodel, I. Voskoboinik, 2024, Frontiers in pharmacology.