P. Luthra

发表

Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly

Wah Chiu, Gregory R. Bowman, Michael L. Gross, 2018, Cell.

An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.

W. Chiu, R. Davey, Z. Otwinowski, 2015, Cell reports.

Development of RNA aptamers targeting Ebola virus VP35.

Gaya K Amarasinghe, P. Luthra, Gai Liu, 2013, Biochemistry.

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

R. Davey, P. Luthra, C. Basler, 2018, Antiviral research.

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

R. Pappu, P. Luthra, C. Basler, 2017, Nature Microbiology.

Systematic review and meta‐analysis: opportunistic infections and malignancies during treatment with anti‐integrin antibodies in inflammatory bowel disease

A. Ford, P. Luthra, L. Peyrin-Biroulet, 2015, Alimentary pharmacology & therapeutics.

Varenicline Prevents SARS-CoV-2 Infection In Vitro and in Rhesus Macaques

P. Luthra, Kathleen G. Lanzer, T. Cookenham, 2021, bioRxiv.

The Antiviral Drug Arbidol Inhibits Zika Virus

S. Polyak, P. Luthra, C. Basler, 2018, Scientific Reports.

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge.

H. Ebihara, P. Luthra, C. Basler, 2019, Cell reports.

Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways

P. Luthra, C. Basler, Timothy R Keiffer, 2019, Journal of Virology.

The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing

Timothy B. Stockwell, T. Stockwell, V. Puri, 2017, PloS one.

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

H. Ebihara, P. Luthra, Gai Liu, 2013, Cell host & microbe.

Assays to Measure Suppression of Type I Interferon Responses by Filovirus VP35 Proteins.

P. Luthra, C. Basler, 2017, Methods in molecular biology.

Function of the Respiratory Syncytial Virus Small Hydrophobic Protein

P. Luthra, B. He, K. Tran, 2007, Journal of Virology.

Identification of a Phosphorylation Site within the P Protein Important for mRNA Transcription and Growth of Parainfluenza Virus 5

P. Luthra, B. He, Haeyoung Yoon, 2011, Journal of Virology.

Severe influenza pneumonitis in children with inherited TLR3 deficiency

J. Casanova, J. Orange, L. Notarangelo, 2019, The Journal of experimental medicine.

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

B. Posner, P. Luthra, C. Basler, 2018, Antiviral research.

Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

R. Silverman, P. Luthra, B. He, 2011, Proceedings of the National Academy of Sciences.

The roles of large (L) gene of parainfluenza virus 5 in the host signaling pathways

P. Luthra, 2011 .

AKT1-Dependent Activation of NF-κB by the L Protein of Parainfluenza Virus 5

P. Luthra, M. Wolfgang, B. He, 2008, Journal of Virology.

High throughput screening assay to identify small molecule inhibitors of Marburg virus VP40 protein.

R. Plemper, R. Davey, Julien Sourimant, 2020, ACS infectious diseases.

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

D. Chaussabel, J. Casanova, L. Notarangelo, 2015, Science.

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication

Robyn M. Kaake, Gwendolyn M. Jang, N. Krogan, 2018, Cell.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.

The Antiviral Drug Arbidol Inhibits Zika Virus

S. Polyak, P. Luthra, C. Basler, 2018, Scientific Reports.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

N. Krogan, Jeffrey R. Johnson, P. Luthra, 2017, Journal of Virology.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Garrett M. Ginell, P. Luthra, C. Basler, 2018, Cell reports.

Cardiac inflammation in COVID-19: Lessons from heart failure

Sathya D. Unudurthi, Rajendran J C Bose, P. Luthra, 2020, Life Sciences.

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

S. Aguirre, A. García-Sastre, S. Tripathi, 2017, Nature Microbiology.

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

S. Aguirre, A. García-Sastre, A. Fernández-Sesma, 2017, mBio.

PLK1 Down-Regulates Parainfluenza Virus 5 Gene Expression

P. Luthra, B. He, Zhuo Li, 2009, PLoS pathogens.

The V Protein of Mumps Virus Plays a Critical Role in Pathogenesis

Jianguo Wu, P. Luthra, P. Rota, 2011, Journal of Virology.

Ebola Virus VP35 Interaction with Dynein LC8 Regulates Viral RNA Synthesis

P. Luthra, C. Basler, D. Leung, 2015, Journal of Virology.

In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.

Wei Xu, Gaya K Amarasinghe, Zbyszek Otwinowski, 2014, Journal of molecular biology.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

P. Luthra, C. Basler, D. Leung, 2018, Cell reports.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis

Chao Wu, P. Luthra, C. Basler, 2017, Nature Communications.