C. Basler

C. Basler, G. Amarasinghe, 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions

R. Sachidanandam, C. Basler, I. Kuzmin, 2017, Journal of Virology.

Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus

M. Katze, J. Taubenberger, A. García-Sastre, 2004, Journal of Virology.

Replication and Mortality in Mice and Neutrophils in Limiting Virus Functional Roles of Alveolar Macrophages Genes from the 1918 Pandemic Virus : Pathogenicity of Influenza Viruses with

J. Taubenberger, A. García-Sastre, T. Tumpey, 2005 .

A high throughput Cre-lox activated viral membrane fusion assay identifies pharmacological inhibitors of HIV entry.

C. Basler, T. Swartz, Benjamin K. Chen, 2016, Virology.

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

R. Davey, P. Luthra, C. Basler, 2018, Antiviral research.

Filovirus Strategies to Escape Antiviral Responses.

C. Basler, D. Leung, G. Amarasinghe, 2017, Current topics in microbiology and immunology.

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

H. Feldmann, J. M. Binning, C. Basler, 2013, PLoS pathogens.

A novel mechanism of immune evasion mediated by Ebola virus soluble glycoprotein

C. Basler, 2013, Expert review of anti-infective therapy.

Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses.

M. Gross, Hao Zhang, Britney Johnson, 2016, Journal of molecular biology.

Newcastle Disease Virus V Protein Is a Determinant of Host Range Restriction

A. García-Sastre, P. Palese, C. Basler, 2003, Journal of Virology.

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Miguel Correa Marrero, Robyn M. Kaake, Gwendolyn M. Jang, 2020, Science.

ReplicationBodies Are a Site of Ebolavirus

H. Herwig, C. Basler, O. Dolnik, 2012 .

Marburg Virus VP40 Antagonizes Interferon Signaling in a Species-Specific Manner

C. Basler, Charalampos Valmas, 2011, Journal of Virology.

Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus

C. Basler, Charalampos Valmas, O. Martinez, 2010, PLoS pathogens.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

C. Basler, A. R. Feagins, Alicia R. Feagins, 2015, Virology.

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response

C. Basler, Benhur Lee, Alexander N. Freiberg, 2016, PLoS pathogens.

The VP40 Protein of Marburg Virus Exhibits Impaired Budding and Increased Sensitivity to Human Tetherin following Mouse Adaptation

C. Basler, A. R. Feagins, Alicia R. Feagins, 2014, Journal of Virology.

The tumour suppressor CYLD is a negative regulator of RIG‐I‐mediated antiviral response

R. Xavier, Aylwin Ng, C. Horvath, 2008, EMBO reports.

Filoviral Immune Evasion Mechanisms

C. Basler, D. Leung, G. Amarasinghe, 2011, Viruses.

Human Monoclonal Antibodies to Pandemic 1957 H2N2 and Pandemic 1968 H3N2 Influenza Viruses

J. Crowe, K. Edwards, Jens C. Krause, 2012, Journal of Virology.

Naturally Occurring Human Monoclonal Antibodies Neutralize both 1918 and 2009 Pandemic Influenza A (H1N1) Viruses

J. Crowe, Jens C. Krause, T. Tumpey, 2009, Journal of Virology.

Chimeric Influenza A Viruses with a Functional Influenza B Virus Neuraminidase or Hemagglutinin

A. García-Sastre, P. Palese, C. Basler, 2003, Journal of Virology.

Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells

C. Basler, Man-Seong Park, Charalampos Valmas, 2011, Immunology and cell biology.

Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

Abraham J. Qavi, J. Peiris, M. Gross, 2021, iScience.

Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication

Stacie A. Chvatal, C. Basler, K. Holden, 2021, Cell Reports.

Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain

Abraham J. Qavi, M. Gross, S. Valkenburg, 2020, bioRxiv.

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

R. Pappu, P. Luthra, C. Basler, 2017, Nature Microbiology.

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

Z. Otwinowski, J. Nix, C. Basler, 2010, Nature Structural &Molecular Biology.

A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus Hemagglutinin

J. Crowe, Jens C. Krause, T. Tumpey, 2011, Journal of Virology.

Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain.

C. Basler, Charalampos Valmas, O. Martinez, 2007, Virology.

The Antiviral Drug Arbidol Inhibits Zika Virus

S. Polyak, P. Luthra, C. Basler, 2018, Scientific Reports.

The N- and C-Terminal Domains of the NS1 Protein of Influenza B Virus Can Independently Inhibit IRF-3 and Beta Interferon Promoter Activation

A. García-Sastre, T. Wolff, C. Basler, 2004, Journal of Virology.

DRBP76 associates with Ebola virus VP35 and suppresses viral polymerase function.

Joshua C. Johnson, C. Basler, D. Leung, 2011, The Journal of infectious diseases.

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge.

H. Ebihara, P. Luthra, C. Basler, 2019, Cell reports.

Editorial overview: Emerging viruses

P. Woo, C. Basler, 2014, Current Opinion in Virology.

Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

C. Basler, C. Mire, T. Geisbert, 2019, Scientific Reports.

Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

C. Basler, C. Mire, T. Geisbert, 2016, Journal of Virology.

The immunomodulating V and W proteins of Nipah virus determine disease course

C. Basler, C. Mire, T. Geisbert, 2015, Nature Communications.

Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression

J. Forwood, C. Basler, I. Messaoudi, 2020, Journal of Virology.

Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line

Timothy B. Stockwell, T. Stockwell, R. Sachidanandam, 2016, mSphere.

Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry.

V. Volchkov, C. Basler, O. Martinez, 2011, The Journal of infectious diseases.

Taxonomy of the order Mononegavirales: update 2019

R. Lamb, P. Formenty, M. Shi, 2019, Archives of Virology.

Taxonomy of the order Mononegavirales: update 2017

R. Lamb, P. Formenty, J. Werren, 2017, Archives of Virology.

Nipah Virus V and W Proteins Have a Common STAT1-Binding Domain yet Inhibit STAT1 Activation from the Cytoplasmic and Nuclear Compartments, Respectively

A. García-Sastre, P. Palese, M. Shaw, 2004, Journal of Virology.

Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways

P. Luthra, C. Basler, Timothy R Keiffer, 2019, Journal of Virology.

The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing

Timothy B. Stockwell, T. Stockwell, V. Puri, 2017, PloS one.

Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection

C. Basler, Benjamin Yen, Benjamin C. Yen, 2016, Journal of Virology.

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

H. Ebihara, P. Luthra, Gai Liu, 2013, Cell host & microbe.

Basic Residues within the Ebolavirus VP35 Protein Are Required for Its Viral Polymerase Cofactor Function

J. M. Binning, C. Basler, D. Leung, 2010, Journal of Virology.

Ebolavirus VP35 is a multifunctional virulence factor.

C. Basler, D. Leung, G. Amarasinghe, 2010, Virulence.

The Ebola virus protein VP35, impairs the function of the 1 2 interferon regulatory factor-activating kinases, IKKε

C. Basler, Washington B Cárdenas, Kathleen C. Prins, 2009 .

Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain.

J. Nix, C. Basler, D. Leung, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Ebola Virus Produces Discrete Small Noncoding RNAs Independently of the Host MicroRNA Pathway Which Lack RNA Interference Activity in Bat and Human Cells

S. Widen, C. Basler, T. Wood, 2019, Journal of Virology.

The makings of a killer

A. García-Sastre, P. Palese, C. Basler, 2002, Nature Medicine.

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

John S. Hu, Steven B. Bradfute, E. Koonin, 2021, Archives of virology.

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

Steven B. Bradfute, E. Koonin, Y. Wolf, 2020, Archives of virology.

Taxonomy of the order Mononegavirales: update 2018

E. Koonin, Y. Wolf, R. Lamb, 2018, Archives of Virology.

West African Ebola Virus Strains: Unstable and Ready to Invade?

C. Basler, 2017, Cell Host and Microbe.

Portrait of a killer: genome of the 2014 EBOV outbreak strain.

C. Basler, 2014, Cell host & microbe.

Assays to Measure Suppression of Type I Interferon Responses by Filovirus VP35 Proteins.

P. Luthra, C. Basler, 2017, Methods in molecular biology.

Sensing RNA virus infections.

A. García-Sastre, C. Basler, 2007, Nature chemical biology.

Marburgvirus VP40 antagonizes IFN signaling in a species-specific manner 1

C. Basler, Charalampos Valmas, 2011 .

Optimization of Assays to Assess Dendritic Cell Activation and/or Anergy in Ebola Infection.

C. Basler, 2012 .

Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin (cid:2) Proteins with Activated STAT1 (cid:1)

C. Basler, S. Reid, Charalampos Valmas, 2007 .

A Sensitive in Vitro High-Throughput Screen To Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface.

D. Moir, Britney Johnson, Gai Liu, 2017, ACS infectious diseases.

High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication.

M. Shaw, C. Basler, A. Bukreyev, 2015, ACS infectious diseases.

Correction: Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice

P. Nelson, K. Schughart, C. Basler, 2014, PLoS Pathogens.

Taxonomy of the order Mononegavirales: second update 2018

R. Lamb, P. Formenty, J. Dye, 2019, Archives of Virology.

Structural basis for Marburg virus VP35–mediated immune evasion mechanisms

Z. Otwinowski, Gai Liu, C. Basler, 2012, Proceedings of the National Academy of Sciences.

Marburg Virus VP40 Antagonizes Interferon Signaling in a Species-Speciﬁc Manner (cid:1)

C. Basler, Charalampos Valmas, 2011 .

Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins.

Z. Otwinowski, J. Nix, C. Basler, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Ebola Virus VP24 Binds Karyopherin (cid:2) 1 and Blocks STAT1 Nuclear Accumulation

V. Volchkov, M. Shaw, C. Basler, 2006 .

Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene

R. Davey, C. Basler, M. Edwards, 2022, mBio.

Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus

R. Belshe, A. García-Sastre, R. Hai, 2010, Nature communications.

Marburg Virus VP24 Protein Relieves Suppression of the NF-κB Pathway Through Interaction With Kelch-like ECH-Associated Protein 1.

C. Basler, M. Edwards, 2015, The Journal of infectious diseases.

Amino Acid Residue at Position 79 of Marburg Virus VP40 Confers Interferon Antagonism in Mouse Cells.

C. Basler, A. R. Feagins, Alicia R. Feagins, 2015, The Journal of infectious diseases.

Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2

M. Gross, Z. Otwinowski, C. Basler, 2021, Proceedings of the National Academy of Sciences.

Human Monoclonal Antibodies to Pandemic 1957 H2N2 and Pandemic 1968 H3N2 Inﬂuenza Viruses

J. Crowe, K. Edwards, Jens C. Krause, 2012 .

Small molecule compounds that inhibit antioxidant response gene expression in an inducer-dependent manner.

R. Plemper, Julien Sourimant, D. Moir, 2020, ACS infectious diseases.

A Single Amino Acid Substitution in 1918 Inﬂuenza Virus Hemagglutinin Changes Receptor Binding Speciﬁcity

J. Taubenberger, A. García-Sastre, T. Tumpey, 2005 .

Molecular pathogenesis of viral hemorrhagic fever

C. Basler, 2017, Seminars in Immunopathology.

Prothymosin α variants isolated from CD8+ T cells and cervicovaginal fluid suppress HIV-1 replication through type I interferon induction.

H. van Bakel, Xintong Chen, A. García-Sastre, 2015, The Journal of infectious diseases.

Cellular Splicing Factor RAF-2p48/NPI-5/BAT1/UAP56 Interacts with the Influenza Virus Nucleoprotein and Enhances Viral RNA Synthesis

Robert E. O'Neill, K. Nagata, P. Palese, 2001, Journal of Virology.

Taxonomy of the order Mononegavirales: update 2016

R. Lamb, P. Formenty, M. Shi, 2016, Archives of Virology.

Current status of small molecule drug development for Ebola virus and other filoviruses.

C. Basler, M. Edwards, 2019, Current opinion in virology.

The helicase senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

Matthew S. Miller, H. van Bakel, S. Heinz, 2015, Nature Immunology.

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

B. Posner, P. Luthra, C. Basler, 2018, Antiviral research.

Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses.

C. Basler, P. Aguilar, Christopher F Basler, 2008, Antiviral research.

Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus

David E. Swayne, Hui Zeng, Jeffery K. Taubenberger, 2005, Science.

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

John S. Hu, Steven B. Bradfute, E. Koonin, 2021, Archives of Virology.

Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates

G. Dougan, Bing Chen, W. Jacobs, 2022, Proceedings of the National Academy of Sciences.

The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway.

Wei Xu, Gaya K Amarasinghe, Lauren N. Speller, 2014, Cell reports.

Newcastle Disease Virus (NDV)-Based Assay Demonstrates Interferon-Antagonist Activity for the NDV V Protein and the Nipah Virus V, W, and C Proteins

Nicole M. Bouvier, J. Muñoz-Jordán, A. García-Sastre, 2003, Journal of Virology.

VIRUSES AND THE TYPE I INTERFERON ANTIVIRAL SYSTEM: INDUCTION AND EVASION

A. García-Sastre, C. Basler, 2002, International reviews of immunology.

Capsid Protein of Eastern Equine Encephalitis Virus Inhibits Host Cell Gene Expression

S. Weaver, C. Basler, P. Aguilar, 2007, Journal of Virology.

Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.

J. Taubenberger, A. García-Sastre, T. Tumpey, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Mechanisms of anti-vesicular stomatitis virus activity of deazaneplanocin and its 3-brominated analogues.

C. Basler, S. Khadka, Caroline G. Williams, 2021, Antiviral research.

Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets

N. Krogan, C. Basler, D. Leung, 2019, Antiviral research.

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

Jian Jin, Xiaoting Chen, Miriam Merad, 2016, Science.

Vaccine Potential of Nipah Virus-Like Particles

C. Basler, J. Barr, Michael Sherman, 2011, PloS one.

High throughput screening assay to identify small molecule inhibitors of Marburg virus VP40 protein.

R. Plemper, R. Davey, Julien Sourimant, 2020, ACS infectious diseases.

Sequence of the immunoregulatory early region 3 and flanking sequences of adenovirus type 35.

C. Basler, G. Droguett, M. Horwitz, 1996, Gene.

Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice

David E. Swayne, Jeffery K. Taubenberger, J. Taubenberger, 2005, Journal of Virology.

The Ebola virus VP35 protein functions as a type I IFN antagonist.

V. Volchkov, H. Klenk, A. García-Sastre, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

D. Chaussabel, J. Casanova, L. Notarangelo, 2015, Science.

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication

Robyn M. Kaake, Gwendolyn M. Jang, N. Krogan, 2018, Cell.

Functional Replacement of the Carboxy-Terminal Two-Thirds of the Influenza A Virus NS1 Protein with Short Heterologous Dimerization Domains

Robert H. Silverman, Bryan R. G. Williams, B. Williams, 2002, Journal of Virology.

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses

J. Forwood, J. Batra, C. Basler, 2018, Nature Communications.

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Wei Xu, Gaya K Amarasinghe, Rohit V Pappu, 2014, Cell host & microbe.

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation.

V. Volchkov, M. Shaw, C. Basler, 2006, Journal of virology.

Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus

C. Basler, G. Amarasinghe, I. Messaoudi, 2015, Nature Reviews Microbiology.

Taxonomy of the order Mononegavirales: update 2017

R. Lamb, P. Formenty, J. Werren, 2017, Archives of Virology.

Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence

James E Crowe, J. Crowe, B. Briney, 2011, The Journal of Immunology.

ConvergenceSequence Divergence and Interclonal Repertoires Diversify by B Cell Intraclonal Epitope-Specific Human Influenza Antibody

J. Crowe, B. Briney, Jens C. Krause, 2011 .

Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions

James C. Sacchettini, William R. Jacobs, David Alland, 2011, Antimicrobial Agents and Chemotherapy.

Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain.

C. Basler, D. Leung, G. Amarasinghe, 2010, Journal of molecular biology.

Nuclear Localization of the Nipah Virus W Protein Allows for Inhibition of both Virus- and Toll-Like Receptor 3-Triggered Signaling Pathways

P. Palese, M. Shaw, C. Basler, 2005, Journal of Virology.

Interactions of the Nipah Virus P, V, and W Proteins across the STAT Family of Transcription Factors

C. Basler, Timothy R Keiffer, Michael J. Ciancanelli, 2020, mSphere.

Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression

J. Forwood, C. Basler, I. Messaoudi, 2020, Journal of Virology.

Nipah and hendra virus interactions with the innate immune system.

C. Basler, 2012, Current topics in microbiology and immunology.

Nipah Virus Sequesters Inactive STAT1 in the Nucleus via a P Gene-Encoded Mechanism

V. Volchkov, V. Volchkova, M. Shaw, 2009, Journal of Virology.

Nipah Virus Edits Its P Gene at High Frequency To Express the V and W Proteins

V. Volchkov, V. Volchkova, P. Palese, 2009, Journal of Virology.

Inclusion Bodies Are a Site of Ebolavirus Replication

Thomas Hoenen, Heinz Feldmann, Gordian Schudt, 2012, Journal of Virology.

Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus

M. Katze, J. Taubenberger, A. García-Sastre, 2004, Journal of Virology.

Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus

J. Taubenberger, A. García-Sastre, T. Tumpey, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

David E. Swayne, Adolfo García-Sastre, Jeffery K. Taubenberger, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Immunological features underlying viral hemorrhagic fevers.

C. Basler, I. Messaoudi, 2015, Current opinion in immunology.

Transcriptional Analysis of Lymphoid Tissues from Infected Nonhuman Primates Reveals the Basis for Attenuation and Immunogenicity of an Ebola Virus Encoding a Mutant VP35 Protein

C. Basler, I. Messaoudi, T. Geisbert, 2021, Journal of Virology.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.

Ebola Virus VP24 Binds Karyopherin α1 and Blocks STAT1 Nuclear Accumulation

V. Volchkov, M. Shaw, C. Basler, 2006, Journal of Virology.

The Ebola Virus VP35 Protein Inhibits Activation of Interferon Regulatory Factor 3

H. Klenk, M. Bray, A. García-Sastre, 2003, Journal of Virology.

Ebola and Marburg virus infection in bats induces a systemic response

Michael F. Covington, R. Sachidanandam, C. Basler, 2020, bioRxiv.

The Antiviral Drug Arbidol Inhibits Zika Virus

S. Polyak, P. Luthra, C. Basler, 2018, Scientific Reports.

A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

Ian A. Wilson, James Stevens, Jeffery K. Taubenberger, 2005, Journal of Virology.

Taxonomy of the order Mononegavirales: update 2019

R. Lamb, P. Formenty, M. Shi, 2019, Archives of Virology.

Taxonomy of the order Mononegavirales: second update 2018

R. Lamb, P. Formenty, J. Dye, 2019, Archives of Virology.

Taxonomy of the order Mononegavirales: update 2016

R. Lamb, P. Formenty, M. Shi, 2016, Archives of Virology.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

N. Krogan, Jeffrey R. Johnson, P. Luthra, 2017, Journal of Virology.

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

P. Formenty, J. Dye, K. Chandran, 2017, Viruses.

The role of antigen-presenting cells in filoviral hemorrhagic fever: Gaps in current knowledge

C. Basler, O. Martinez, L. Leung, 2012, Antiviral Research.

Marburg and Ebola Virus Infections Elicit a Complex, Muted Inflammatory State in Bats

Michael F. Covington, R. Sachidanandam, C. Basler, 2023, Viruses.

Ebola and Marburg virus infection in bats induces a systemic response

Michael F. Covington, R. Sachidanandam, C. Basler, 2020, bioRxiv.

Marburg and Ebola virus infections elicit a muted inflammatory state in bats

Michael F. Covington, R. Sachidanandam, C. Basler, 2021 .

Innate immune evasion by filoviruses.

C. Basler, 2015, Virology.

Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus.

C. Basler, Christos Fytas, G. Fytas, 2010, Bioorganic chemistry.

Structure of the Ebola VP35 interferon inhibitory domain

J. Nix, C. Basler, D. Leung, 2009, Proceedings of the National Academy of Sciences.

Non‐canonical proline‐tyrosine interactions with multiple host proteins regulate Ebola virus infection

N. Krogan, M. Gross, R. Davey, 2021, The EMBO journal.

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

N. Krogan, M. Gross, R. Davey, 2020, bioRxiv.

Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

Timothy B. Stockwell, T. Stockwell, M. Mahajan, 2014, mBio.

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

Lucy A. Perrone, A. García-Sastre, T. Tumpey, 2008, Proceedings of the National Academy of Sciences.

A Mutation in the Ebola Virus Envelope Glycoprotein Restricts Viral Entry in a Host Species- and Cell-Type-Specific Manner

K. Chandran, C. Basler, O. Martinez, 2013, Journal of Virology.

3' untranslated regions of Marburg and Ebola virus mRNAs possess negative regulators of translation that are modulated by ADAR1 editing.

C. Basler, S. Khadka, Caroline G. Williams, 2021, Journal of virology.

Marburg and Ebola Virus mRNA 3′ Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

C. Basler, S. Khadka, Caroline G. Williams, 2021, Journal of Virology.

Marburg and Ebola Virus mRNA 3′ Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

C. Basler, S. Khadka, Caroline G. Williams, 2021, bioRxiv.

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

Joshua C. Johnson, G. Olinger, C. Basler, 2013, Journal of Virology.

Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles.

N. Mulherkar, K. Chandran, C. Basler, 2011, The Journal of infectious diseases.

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

V. Volchkov, V. Volchkova, C. Basler, 2010, Journal of Virology.

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKKε and TBK-1

C. Basler, Washington B Cárdenas, Washington B. Cárdenas, 2009, Journal of Virology.

Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein.

C. Basler, S. Reid, Washington B Cárdenas, 2005, Virology.

ICTV Virus Taxonomy Profile: Filoviridae

P. Formenty, J. Dye, K. Chandran, 2019, The Journal of general virology.

Unconventional secretion of Ebola virus matrix protein VP40.

V. Volchkov, C. Basler, S. Reid, 2011, The Journal of infectious diseases.

Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein

A. García-Sastre, T. Muster, C. Horvath, 2000, Journal of Virology.

Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling

Erica Ollmann Saphire, Michael Gale, Amy L. Hartman, 2006, Journal of Virology.

Interferon Antagonists Encoded by Emerging RNA Viruses

C. Basler, 2005 .

Mutation of YMYL in the Nipah Virus Matrix Protein Abrogates Budding and Alters Subcellular Localization

C. Basler, Michael J. Ciancanelli, 2006, Journal of Virology.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Garrett M. Ginell, P. Luthra, C. Basler, 2018, Cell reports.

The L Gene of J Paramyxovirus Plays a Critical Role in Viral Pathogenesis

C. Basler, B. He, Lin‐Fa Wang, 2013, Journal of Virology.

Neutralizing Anti-Influenza Virus Monoclonal Antibodies: Therapeutics and Tools for Discovery

C. Basler, O. Martinez, Tshidi Tsibane, 2009, International reviews of immunology.

Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

A. García-Sastre, C. Basler, C. Muñoz-Fontela, 2017, Journal of Virology.

Effects of Overexpression of the Egyptian Fruit Bat Innate Immune Genes on Filovirus Infections in the Host Cells

C. Basler, I. Kuzmin, A. Bukreyev, 2021, Frontiers in Virology.

Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines

A. García-Sastre, R. Hai, P. Palese, 2010, PLoS pathogens.

Ebolavirus VP24 Binding to Karyopherins Is Required for Inhibition of Interferon Signaling

V. Volchkov, C. Basler, S. Reid, 2009, Journal of Virology.

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

S. Aguirre, A. García-Sastre, S. Tripathi, 2017, Nature Microbiology.

Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses

James E. Crowe, Damian C. Ekiert, Ian A. Wilson, 2012, PLoS pathogens.

Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.

C. Basler, D. Leung, G. Amarasinghe, 2016, Journal of molecular biology.

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

S. Aguirre, A. García-Sastre, A. Fernández-Sesma, 2017, mBio.

Molecular mechanisms of viral inhibitors of RIG-I-like receptors.

C. Basler, D. Leung, G. Amarasinghe, 2012, Trends in microbiology.

Cooperation of the Ebola Virus Proteins VP40 and GP1,2 with BST2 To Activate NF-κB Independently of Virus-Like Particle Trapping

C. Basler, J. Guatelli, Maryan Rizk, 2017, Journal of Virology.

A Recombinant Influenza A Virus Expressing anRNA-Binding-Defective NS1 Protein Induces High Levels of BetaInterferon and Is Attenuated inMice

A. García-Sastre, C. Basler, Nicola R. Donelan, 2003, Journal of Virology.

Effects of Influenza A Virus NS1 Protein on Protein Expression: the NS1 Protein Enhances Translation and Is Not Required for Shutoff of Host Protein Synthesis

A. García-Sastre, T. Muster, C. Horvath, 2002, Journal of Virology.

1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans.

Matthew S. Miller, R. Hai, P. Palese, 2013, The Journal of infectious diseases.

A Novel Paramyxovirus?

A. García-Sastre, P. Palese, C. Basler, 2005, Emerging infectious diseases.

Subgroup B adenovirus type 35 early region 3 mRNAs differ from those of the subgroup C adenoviruses.

C. Basler, M. Horwitz, 1996, Virology.

COVID-19 Vaccine-Induced Lichenoid Eruptions—Clinical and Histopathologic Spectrum in a Case Series of Fifteen Patients with Review of the Literature

M. Lebwohl, R. Phelps, C. Basler, 2023, Vaccines.

Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material

C. Basler, Alexander S. Jureka, Caroline G. Williams, 2021, bioRxiv.

Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells.

Joshua C. Johnson, G. Olinger, C. Basler, 2014, Antiviral research.

Propagation, Inactivation, and Safety Testing of SARS-CoV-2

C. Basler, J. Silvas, Alexander S. Jureka, 2020, bioRxiv.

Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis

Florian Krammer, Matthew S. Miller, Domenico Tortorella, 2013, Science Translational Medicine.

A Five-Amino-Acid Deletion of the Eastern Equine Encephalitis Virus Capsid Protein Attenuates Replication in Mammalian Systems but Not in Mosquito Cells

E. Wang, S. Weaver, C. Basler, 2008, Journal of Virology.

Hemagglutinin-Pseudotyped Green Fluorescent Protein-Expressing Influenza Viruses for the Detection of Influenza Virus Neutralizing Antibodies

John Steel, Thomas M. Moran, A. García-Sastre, 2009, Journal of Virology.

Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Stacie A. Chvatal, C. Basler, J. Silvas, 2020, bioRxiv.

Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism

J. Forwood, C. Basler, M. Edwards, 2023, Viruses.

Ebola Virus VP 35 Protein Binds Double-Stranded RNA and Inhibits Alpha / Beta Interferon Production Induced by RIGI Signaling

E. Saphire, M. Gale, Y. Loo, 2006 .

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

J. Forwood, C. Basler, M. Stewart, 2022, Nature Communications.

Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein

Abraham J. Qavi, J. Peiris, M. Gross, 2021, STAR Protocols.

Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin α Proteins with Activated STAT1

C. Basler, S. Reid, Charalampos Valmas, 2008, Journal of Virology.

Influenza viruses: basic biology and potential drug targets.

C. Basler, 2007, Infectious disorders drug targets.

Ebola Virus VP35 Interaction with Dynein LC8 Regulates Viral RNA Synthesis

P. Luthra, C. Basler, D. Leung, 2015, Journal of Virology.

In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.

Wei Xu, Gaya K Amarasinghe, Zbyszek Otwinowski, 2014, Journal of molecular biology.

Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition

Joshua C. Johnson, G. Olinger, C. Basler, 2010, Cellular microbiology.

Phylogenetics and Pathogenesis of Early Avian Influenza Viruses (H5N1), Nigeria

C. Basler, D. Suarez, D. Swayne, 2008, Emerging infectious diseases.

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24

Chao Wu, C. Basler, G. Amarasinghe, 2023, Viruses.

Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

Lucy A. Perrone, I. Wilson, E. Altschuler, 2012, Nature.

Taxonomy of the order Mononegavirales: update 2018

E. Koonin, Y. Wolf, P. Formenty, 2018, Archives of Virology.

Virus Taxonomy The ICTV Report on Virus Classification and Taxon Nomenclature Secoviridae Chapter Secoviridae

P. Formenty, J. Dye, K. Chandran, 2020 .

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

P. Luthra, C. Basler, D. Leung, 2018, Cell reports.

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

Joshua C. Johnson, G. Olinger, C. Basler, 2013, Journal of Virology.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.

Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles.

N. Mulherkar, K. Chandran, C. Basler, 2011, The Journal of infectious diseases.

New hope in the search for Ebola virus treatments.

C. Basler, 2014, Immunity.

Innate Immunity: Defeating

C. Basler, 2008 .

A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus Hemagglutinin

J. Crowe, Jens C. Krause, T. Tumpey, 2011, Journal of Virology.

Pandemic Virus Characterization of the Reconstructed 1918 Spanish Influenza

N. Cox, J. Taubenberger, A. García-Sastre, 2012 .

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis

Chao Wu, P. Luthra, C. Basler, 2017, Nature Communications.

Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics

N. Hacohen, P. Blainey, C. Basler, 2024, bioRxiv.

Viral Targeting of Importin Alpha-Mediated Nuclear Import to Block Innate Immunity

J. Forwood, C. Basler, D. Leung, 2023, Cells.

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

Benjamin J. Polacco, Robyn M. Kaake, Steven J. Schrodi, 2023, Nature communications.

A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4

C. Basler, U. Aryal, Callie J. Donahue, 2024, Research square.