J. Chong

发表

Structural Basis for Eukaryotic Transcription-Coupled DNA Repair Initiation

Adam D. Wier, F. Dimaio, Wei Wang, 2017, Nature.

Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity

Xuhui Huang, Dong Wang, Jun Xu, 2014, Proceedings of the National Academy of Sciences.

Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers

Wei Wang, Dong Wang, Xiang-Dong Fu, 2020, Proceedings of the National Academy of Sciences.

Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog

P. Russell, Wei Wang, Dong Wang, 2019, Proceedings of the National Academy of Sciences.

Pyrene-based quantitative detection of the 5-formylcytosine loci symmetry in the CpG duplex content during TET-dependent demethylation.

Dong Wang, Jun Xu, J. Chong, 2014, Angewandte Chemie.

Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution

Wei Wang, Xuhui Huang, Dong Wang, 2016, Nucleic acids research.

Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures

Dong Wang, Jun Xu, J. Chong, 2021, Nucleic acids research.

Impact of template backbone heterogeneity on RNA polymerase II transcription

Wei Wang, Xuhui Huang, Dong Wang, 2015, Nucleic acids research.

leaving group base pair recognition during polymerase nucleotide incorporation revealed by methylene substitution.

Xuhui Huang, Dong Wang, E. Kool, 2016 .

Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues

Kyle V. Butler, Dong Wang, E. Kool, 2014, Nucleic acids research.

A chemical perspective on transcriptional fidelity: dominant contributions of sugar integrity revealed by unlocked nucleic acids.

Dong Wang, J. Wengel, J. Chong, 2013, Angewandte Chemie.

Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity.

Dong Wang, E. Kool, J. Chong, 2012, Journal of the American Chemical Society.

Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II

Aaron W Feldman, Xuhui Huang, Dong Wang, 2021, Nature Chemical Biology.

RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif

D. Gotte, J. Strathern, Wei Wang, 2016, Proceedings of the National Academy of Sciences.

RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications

Wei Wang, Dong Wang, Jun Xu, 2015, Critical reviews in biochemistry and molecular biology.

Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.

Dong Wang, E. Kool, J. Chong, 2014, DNA repair.

RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair–π and CH–π interactions

Dong Wang, Jun Xu, Juntaek Oh, 2020, Proceedings of the National Academy of Sciences.

Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II

Wei Wang, Dong Wang, M. Kashlev, 2018, Proceedings of the National Academy of Sciences.

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions

A. Gnatt, Dong Wang, M. Kashlev, 2015, Proceedings of the National Academy of Sciences.

Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis.

Dong Wang, S. Lippard, J. Chong, 2013, Journal of the American Chemical Society.

Structural Basis for Eukaryotic Transcription-Coupled DNA Repair Initiation

Adam D. Wier, Wei Wang, Dong Wang, 2017, Nature.

Structural and biochemical analysis of DNA lesion-induced RNA polymerase II arrest.

Dong Wang, Jun Xu, Juntaek Oh, 2019, Methods.

Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis

Wei Wang, Dong Wang, J. Chong, 2017, Proceedings of the National Academy of Sciences.

Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex

Chuan He, Dong Wang, Xiang-Dong Fu, 2015, Nature.

5-Formyl- and 5-carboxyl-cytosine reduce the rate and substrate specificity of RNA polymerase II transcription

Chuan He, Dong Wang, Xingyu Lu, 2012, Nature Structural &Molecular Biology.

RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder

Dong Wang, P. Dervan, Jun Xu, 2022, Proceedings of the National Academy of Sciences.

Strand-specific effect of Rad26 and TFIIS in rescuing transcriptional arrest by CAG trinucleotide repeat slip-outs

Dong Wang, Jun Xu, J. Chong, 2021, Nucleic acids research.

Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.

Wei Wang, Chuan He, Dong Wang, 2017, Journal of the American Chemical Society.

Structural basis of DNA lesion recognition for eukaryotic transcription-coupled nucleotide excision repair.

Wei Wang, Dong Wang, Jun Xu, 2018, DNA repair.

Structural basis of transcription recognition of a hydrophobic unnatural base pair by T7 RNA polymerase

Dong Wang, J. Chong, J. Oh, 2023, Nature Communications.

Molecular Basis of Transcriptional Pausing, Stalling, and Transcription-coupled Repair Initiation.

Dong Wang, Jun Xu, Juntaek Oh, 2020, Biochimica et biophysica acta. Gene regulatory mechanisms.

A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression.

S. Nakajima, Dong Wang, J. Chong, 2014, Chemical science.

BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology

Michael K. Gilson, Michael Baitaluk, Tiqing Liu, 2015, Nucleic Acids Res..

Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif

P. Russell, J. Ranish, R. Conaway, 2014, Proceedings of the National Academy of Sciences.