K. Fredrick

发表

A tRNA methyltransferase paralog is important for ribosome stability and cell division in Trypanosoma brucei

M. A. Rubio, J. Alfonzo, Ian M. C. Fleming, 2016, Scientific Reports.

Ribosomal translocation: one step closer to the molecular mechanism.

Sarah E. Walker, K. Fredrick, S. Shoji, 2009, ACS chemical biology.

Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth

T. Hwa, H. Okano, J. Williamson, 2016, Nature Microbiology.

Paternal chromosome segregation during the first mitotic division determines Wolbachia-induced cytoplasmic incompatibility phenotype

J. Werren, W. Sullivan, K. Fredrick, 2006, Journal of Cell Science.

Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome

R. Bundschuh, J. Ortega, K. Fredrick, 2020, Nucleic acids research.

Analysis of polysomes from bacteria.

K. Fredrick, Daoming Qin, 2013, Methods in enzymology.

Measures of single- versus multiple-round translation argue against a mechanism to ensure coupling of transcription and translation

K. Fredrick, Menglin Chen, 2018, Proceedings of the National Academy of Sciences.

Short spacing between the Shine–Dalgarno sequence and P codon destabilizes codon–anticodon pairing in the P site to promote +1 programmed frameshifting

K. Fredrick, A. Devaraj, 2010, Molecular microbiology.

Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state

C. Dunham, J. Dunkle, C. Fagan, 2013, Proceedings of the National Academy of Sciences.

Reverse translocation of tRNA in the ribosome.

Sarah E. Walker, K. Fredrick, S. Shoji, 2006, Molecular cell.

Modified Aminoglycosides Bind Nucleic Acids in High-Molecular-Weight Complexes

S. Garneau‐Tsodikova, K. Fredrick, Marina Y. Fosso, 2020, Antibiotics.

Tobramycin Variants with Enhanced Ribosome‐Targeting Activity

S. Garneau‐Tsodikova, K. Fredrick, Keith D. Green, 2015, Chembiochem : a European journal of chemical biology.

Distinct functional classes of ram mutations in 16S rRNA

K. Fredrick, A. Devaraj, Sean P. McClory, 2014, RNA.

Epistasis analysis of 16S rRNA ram mutations helps define the conformational dynamics of the ribosome that influence decoding

K. Fredrick, Lanqing Ying, 2016, RNA.

A steric block in translation caused by the antibiotic spectinomycin.

J. Holton, J. Cate, K. Fredrick, 2007, ACS chemical biology.

Structural basis for hygromycin B inhibition of protein biosynthesis.

J. Cate, K. Fredrick, S. Shoji, 2008, RNA.

Catalysis of Ribosomal Translocation by Sparsomycin

H. Noller, K. Fredrick, 2003, Science.

Preparation and evaluation of acylated tRNAs.

Sarah E. Walker, K. Fredrick, 2008, Methods.

Creating ribosomes with an all-RNA 30S subunit P site.

H. Noller, K. Fredrick, Lee Hoang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Promoter architecture in the flagellar regulon of Bacillus subtilis: high-level expression of flagellin by the sigma D RNA polymerase requires an upstream promoter element.

A. Galizzi, J. Helmann, K. Fredrick, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Recognition and positioning of mRNA in the ribosome by tRNAs with expanded anticodons.

Sarah E. Walker, K. Fredrick, 2006, Journal of molecular biology.

Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome

L. Foster, R. Balakrishnan, K. Fredrick, 2017, Proceedings of the National Academy of Sciences.

Role of helix 44 of 16S rRNA in the fidelity of translation initiation.

K. Fredrick, A. Devaraj, Qi Liu, 2012, RNA.

Contribution of ribosomal residues to P-site tRNA binding

Ralf Bundschuh, Kurt Fredrick, R. Bundschuh, 2009, Nucleic acids research.

Control of translation initiation involves a factor‐induced rearrangement of helix 44 of 16S ribosomal RNA

K. Fredrick, Daoming Qin, 2009, Molecular microbiology.

Characterization of 16S rRNA mutations that decrease the fidelity of translation initiation.

K. Fredrick, Nimo M. Abdi, Daoming Qin, 2007, RNA.

Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome

G. Cochrane, P. Bork, S. Sunagawa, 2022, Science.

Ribosomes lacking bS21 gain function to regulate protein synthesis in Flavobacterium johnsoniae

L. Foster, R. Bundschuh, K. Fredrick, 2023, Nucleic acids research.

Comparative Analysis of anti-Shine- Dalgarno Function in Flavobacterium johnsoniae and Escherichia coli

R. Bundschuh, K. Fredrick, Bappaditya Roy, 2021, Frontiers in Molecular Biosciences.

Maturation of 23S rRNA includes removal of helix H1 in many bacteria

R. Bundschuh, K. Fredrick, E. Shatoff, 2021, RNA biology.

Functional Analysis of BipA in E. coli Reveals the Natural Plasticity of 50S Subunit Assembly.

L. Foster, R. Bundschuh, K. Fredrick, 2020, Journal of molecular biology.

Global analysis of protein synthesis in Flavobacterium johnsoniae reveals the use of Kozak-like sequences in diverse bacteria

William D. Baez, R. Bundschuh, K. Fredrick, 2019, Nucleic acids research.

IF2 and unique features of initiator tRNAfMet help establish the translational reading frame

K. Fredrick, Bappaditya Roy, S. Shoji, 2018, RNA biology.

Roles of helix H69 of 23S rRNA in translation initiation

K. Fredrick, Qi Liu, 2015, Proceedings of the National Academy of Sciences.

Accurate translocation of mRNA by the ribosome requires a peptidyl group or its analog on the tRNA moving into the 30S P site.

H. Noller, K. Fredrick, 2002, Molecular cell.

How the Sequence of a Gene Can Tune Its Translation

Kurt Fredrick, M. Ibba, K. Fredrick, 2010, Cell.

The 30S ribosomal P site: a function of 16S rRNA

H. Noller, K. Fredrick, Lee Hoang, 2005, FEBS letters.

Tagging ribosomal protein S7 allows rapid identification of mutants defective in assembly and function of 30 S subunits.

H. Noller, K. Fredrick, G. Dunny, 2000, Journal of molecular biology.

In-cell SHAPE reveals that free 30S ribosome subunits are in the inactive state

Christopher A. Lavender, K. Weeks, Jennifer L. McGinnis, 2015, Proceedings of the National Academy of Sciences.

A role for the 30S subunit E site in maintenance of the translational reading frame.

K. Fredrick, S. Shoji, A. Devaraj, 2009, RNA.

Contribution of 16S rRNA nucleotides forming the 30S subunit A and P sites to translation in Escherichia coli.

Kurt Fredrick, K. Fredrick, Nimo M. Abdi, 2005, RNA.

RNA polymerase's Relationship with the Ribosome: Not So Physical, Most of the Time.

K. Fredrick, Menglin Chen, 2020, Journal of molecular biology.

Roles of elusive translational GTPases come to light and inform on the process of ribosome biogenesis in bacteria

K. Fredrick, Michelle R. Gibbs, 2018, Molecular microbiology.

Intersubunit Bridges of the Bacterial Ribosome.

K. Fredrick, Qi Liu, 2016, Journal of molecular biology.

Dual chemotaxis signaling pathways in Bacillus subtilis: a sigma D-dependent gene encodes a novel protein with both CheW and CheY homologous domains

J. Helmann, K. Fredrick, 1994, Journal of bacteriology.

Chemotaxis in Bacillus subtilis requires either of two functionally redundant CheW homologs

J. Helmann, K. Fredrick, G. Ordal, 1994, Journal of bacteriology.

RiboProP: a probabilistic ribosome positioning algorithm for ribosome profiling

Ralf Bundschuh, Dengke Zhao, William D. Baez, 2018, Bioinform..

The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli

R. Bundschuh, R. Balakrishnan, K. Fredrick, 2014, Nucleic acids research.

FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant

J. Helmann, K. Fredrick, 1996, Journal of bacteriology.

Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress

T. Hwa, H. Okano, J. Williamson, 2018, mBio.

RNA polymerase sigma factor determines start-site selection but is not required for upstream promoter element activation on heteroduplex (bubble) templates.

J. Helmann, K. Fredrick, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Destabilization of the P site codon-anticodon helix results from movement of tRNA into the P/E hybrid state within the ribosome.

Sarah E. Walker, K. Fredrick, Huanyu Wang, 2005, Molecular cell.

Promoter recognition by Bacillus subtilis sigmaW: autoregulation and partial overlap with the sigmaX regulon.

J. Helmann, K. Fredrick, X. Huang, 1998, Journal of bacteriology.

Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome

M. Ibba, M. A. Rubio, J. Alfonzo, 2007, Proceedings of the National Academy of Sciences.

Translation factor LepA contributes to tellurite resistance in Escherichia coli but plays no apparent role in the fidelity of protein synthesis.

C. Hayes, K. Fredrick, S. Shoji, 2010, Biochimie.

Mutations in 16S rRNA that decrease the fidelity of translation

K. Fredrick, A. Devaraj, Sean P. McClory, 2011 .

Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics.

Kurt Fredrick, A. Mankin, K. Fredrick, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Missense suppressor mutations in 16S rRNA reveal the importance of helices h8 and h14 in aminoacyl-tRNA selection.

K. Fredrick, Sean P. McClory, Daoming Qin, 2010, RNA.

Direct measurement of the mechanical work during translocation by the ribosome

H. Noller, I. Tinoco, C. Bustamante, 2014, eLife.

Contribution of intersubunit bridges to the energy barrier of ribosomal translocation

Qi Liu, Kurt Fredrick, K. Fredrick, 2012, Nucleic acids research.

Role of hybrid tRNA-binding states in ribosomal translocation

Barry S. Cooperman, Sarah E. Walker, Kurt Fredrick, 2008, Proceedings of the National Academy of Sciences.

BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

V. Beneš, M. Waldor, F. Cava, 2021, eLife.

Resampling and editing of mischarged tRNA prior to translation elongation.

K. Musier-Forsyth, M. Ibba, K. Fredrick, 2009, Molecular cell.

Promoter Recognition by Bacillus subtilisςW: Autoregulation and Partial Overlap with the ςX Regulon

J. Helmann, K. Fredrick, Xuejun Huang, 1998 .

Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding

C. Dunham, K. Fredrick, E. Hoffer, 2018, Nucleic acids research.

Bifacial PNA Complexation Inhibits Enzymatic Access to DNA and RNA

K. Fredrick, Xijun Piao, D. Bong, 2014, Chembiochem : a European journal of chemical biology.

Structure of the ribosome at 5.5 A resolution and its interactions with functional ligands.

T. Earnest, H. Noller, J. Cate, 2001, Cold Spring Harbor symposia on quantitative biology.

The ABCs of the ribosome

M. Ibba, K. Fredrick, 2014, Nature Structural &Molecular Biology.

RNase II is important for A‐site mRNA cleavage during ribosome pausing

C. Hayes, K. Fredrick, F. Garza-Sánchez, 2009, Molecular microbiology.

Roles of the leader-trailer helix and antitermination complex in biogenesis of the 30S ribosomal subunit

R. Bundschuh, K. Fredrick, Benjamin R Warner, 2023, Nucleic acids research.

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

J. Yates, S. Ackerman, K. Fredrick, 2018, Nature.

Roles of specific aminoglycoside–ribosome interactions in the inhibition of translation

K. Fredrick, S. Shoji, Lanqing Ying, 2018, RNA.

Thermus thermophilus 70S containing 16S G347U point mutation and near-cognate ASL Leucine in A site

C. Dunham, K. Fredrick, E. Hoffer, 2018 .