A. Fabbretti

发表

Structure of the 30S translation initiation complex

Bruno P. Klaholz, Stefano Marzi, C. Gualerzi, 2008, Nature.

Structural and functional characterization of the bacterial translocation inhibitor GE82832

C. Gualerzi, A. Fabbretti, L. Brandi, 2012, FEBS letters.

Draft Genome Sequence of Streptomyces sp. Strain AM-2504, Identified by 16S rRNA Comparative Analysis as a Streptomyces kasugaensis Strain

A. Giuliodori, V. Napolioni, A. Fabbretti, 2019, Microbiology Resource Announcements.

Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A

C. Gualerzi, A. Schedlbauer, S. Connell, 2015, Nucleic acids research.

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

T. Steitz, J. Puglisi, C. Gualerzi, 2013, Proceedings of the National Academy of Sciences.

Escherichia coli Ribosomal Protein S1 Unfolds Structured mRNAs Onto the Ribosome for Active Translation Initiation

R. Micura, S. Marzi, P. Romby, 2013, PLoS biology.

Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

C. Gualerzi, S. Connell, D. Gil-Carton, 2016, Nucleic acids research.

Inhibitors Targeting Riboswitches and Ribozymes

C. Gualerzi, I. Moll, A. Fabbretti, 2013 .

Role of temperature-independent lipoplex–cell membrane interactions in the efficiency boost of multicomponent lipoplexes

M. Montani, E. Gratton, C. Gualerzi, 2011, Cancer Gene Therapy.

Engineering color variants of green fluorescent protein (GFP) for thermostability, pH-sensitivity, and improved folding kinetics

A. Fabbretti, R. Spurio, G. Lupidi, 2014, Applied Microbiology and Biotechnology.

Inhibitors of Bacterial Elongation Factor EF‐Tu

A. Giuliodori, A. Fabbretti, 2013 .

A Derivative of the Thiopeptide GE2270A Highly Selective against Propionibacterium acnes

A. Fabbretti, L. Brandi, R. Spurio, 2015, Antimicrobial Agents and Chemotherapy.

Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding

C. Gualerzi, S. Yokoyama, A. Giuliodori, 2016, Proceedings of the National Academy of Sciences.

Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic.

C. Gualerzi, A. Fabbretti, L. Brandi, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Orthoformimycin, a selective inhibitor of bacterial translation elongation from Streptomyces containing an unusual orthoformate.

C. Gualerzi, A. Fabbretti, L. Brandi, 2013, ACS chemical biology.

Antibiotics: targets, mechanisms and resistance.

C. Gualerzi, C. Pon, A. Fabbretti, 2013 .

Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin

Pohl Milón, A. Fabbretti, P. Milón, 2016, Antibiotics.

Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms

C. Gualerzi, S. Marzi, A. Urzhumtsev, 2013, Acta crystallographica. Section D, Biological crystallography.

Ribosomal interaction of Bacillus stearothermophilus translation initiation factor IF2: characterization of the active sites.

C. Gualerzi, C. Pon, A. Fabbretti, 2010, Journal of molecular biology.

Translation initiation factor IF1 of Bacillus stearothermophilus and Thermus thermophilus substitute for Escherichia coli IF1 in vivo and in vitro without a direct IF1–IF2 interaction

C. Gualerzi, C. Pon, A. Fabbretti, 2008, Molecular microbiology.

The translation initiation functions of IF2: targets for thiostrepton inhibition.

C. Gualerzi, S. Marzi, A. Fabbretti, 2004, Journal of molecular biology.

Translation initiation without IF2-dependent GTP hydrolysis

C. Gualerzi, C. Pon, A. Fabbretti, 2012, Nucleic acids research.

The real-time path of translation factor IF3 onto and off the ribosome.

C. Gualerzi, C. Pon, A. Fabbretti, 2007, Molecular cell.

Methods for identifying compounds that specifically target translation.

C. Gualerzi, C. Pon, A. Fabbretti, 2007, Methods in enzymology.

Transient kinetics, fluorescence, and FRET in studies of initiation of translation in bacteria.

M. Rodnina, C. Gualerzi, A. Konevega, 2007, Methods in enzymology.

Translation initiation complex formation in the crenarchaeon Sulfolobus solfataricus.

C. Gualerzi, U. Bläsi, A. Fabbretti, 2009, RNA.

Translation initiation at the root of the cold-shock translational bias

C. Gualerzi, C. Pon, A. Giuliodori, 2011 .

Role of the Initiation Factors in mRNA Start Site Selection and fMet-tRNA Recruitment by Bacterial Ribosomes

C. Gualerzi, C. Pon, A. Fabbretti, 2010 .

Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits.

C. Gualerzi, A. Fabbretti, L. Brandi, 2006, RNA.

Antibiotics Targeting Translation Initiation in Prokaryotes

C. Pon, A. Fabbretti, L. Brandi, 2013 .

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias

C. Gualerzi, C. Pon, A. Fabbretti, 2012, Nucleic acids research.

Initiation of protein synthesis: a target for antimicrobials

C. Gualerzi, C. Pon, A. Fabbretti, 2008, Expert opinion on therapeutic targets.

Role of the ribosome-associated protein PY in the cold-shock response of Escherichia coli

C. Pon, A. Giuliodori, F. Di Pietro, 2013, MicrobiologyOpen.

Time-resolved assembly of a nucleoprotein complex between Shigella flexneri virF promoter and its transcriptional repressor H-NS

A. Giuliodori, A. Fabbretti, R. Spurio, 2014, Nucleic acids research.

Characterization of the Self-Resistance Mechanism to Dityromycin in the Streptomyces Producer Strain

A. Giuliodori, V. Napolioni, A. Fabbretti, 2019, mSphere.

Characterization of the Self-Resistance Mechanism to Dityromycin in the Streptomyces Producer Strain

A. Giuliodori, V. Napolioni, A. Fabbretti, 2019 .

The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.

T. Steitz, C. Gualerzi, A. Fabbretti, 2014, Cell reports.

The dynamic cycle of bacterial translation initiation factor IF3

A. Konevega, A. Fabbretti, R. Spurio, 2021, Nucleic acids research.

How to cope with the quest for new antibiotics

C. Gualerzi, A. Fabbretti, L. Brandi, 2011, FEBS letters.

Initiation of protein synthesis: a target for antimicrobials.

C. Gualerzi, C. Pon, A. Fabbretti, 2008, Expert opinion on therapeutic targets.

Characterization of Bacillus stearothermophilus infA and of its product IF1.

C. Gualerzi, C. Pon, A. Fabbretti, 2009, Gene.

The hns Gene of Escherichia coli Is Transcriptionally Down-Regulated by (p)ppGpp

A. Fabbretti, A. Brandi, M. Giangrossi, 2020, Microorganisms.

Cold-Responsive Regions of Paradigm Cold-Shock and Non-Cold-Shock mRNAs Responsible for Cold Shock Translational Bias

C. Gualerzi, A. Giuliodori, A. Fabbretti, 2019, International journal of molecular sciences.

Engineering color variants of green fluorescent protein (GFP) for thermostability, pH-sensitivity, and improved folding kinetics

A. Fabbretti, R. Spurio, G. Lupidi, 2015, Applied Microbiology and Biotechnology.

The complete, functional and dynamic cycle of the bacterial Initiation Factor 3

A. Konevega, A. Fabbretti, R. Spurio, 2019, bioRxiv.

Title : The complete , functional and dynamic cycle of the bacterial Initiation Factor 3 1 2

A. Konevega, A. Fabbretti, R. Spurio, 2019 .

Antibiotic synergist OM19r reverses aminoglycoside resistance in multidrug-resistant Escherichia coli

A. Giuliodori, A. Fabbretti, Pengfei Li, 2023, Frontiers in Microbiology.

Selection, Identification and Functional Performance of Ammonia-Degrading Microbial Communities from an Activated Sludge for Landfill Leachate Treatment

V. Napolioni, A. Fabbretti, Matteo Picciolini, 2023, Microorganisms.

Development of a graphene oxide-based assay for the sequence-specific detection of double-stranded DNA molecules

A. Giuliodori, A. Fabbretti, A. Brandi, 2017, PloS one.

Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp.

C. Gualerzi, A. Fabbretti, L. Brandi, 2006, Biochemistry.

Antibiotics Targeting the 30S Ribosomal Subunit: A Lesson from Nature to Find and Develop New Drugs.

A. Giuliodori, A. Fabbretti, R. Spurio, 2019, Current Topics in Medicinal Chemistry.

Orthoformimycin inhibits translation elongation by displacing the A-site tRNA and preventing peptide bond formation

C. Gualerzi, A. Schedlbauer, S. Connell, 2021, bioRxiv.

Real-time dynamics of ribosome-ligand interaction by time-resolved chemical probing methods.

C. Gualerzi, C. Pon, A. Giuliodori, 2007, Methods in enzymology.