Y. Guan

发表

Effects of Tween 80 on volume‐regulated chloride channel and cell proliferation in rat basilar artery smooth muscle cell

Ren-Hong Du, Yongbo Tang, Jia-guo Zhou, 2011, The Journal of pharmacy and pharmacology.

Low Chloride–Regulated ClC-5 Contributes to Arterial Smooth Muscle Cell Proliferation and Cerebrovascular Remodeling

Y. Guan, Xiao-fei Lv, Min Gao, 2022, Hypertension.

Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation

Y. Guan, M. Ma, Xiao-fei Lv, 2019, Acta Pharmacologica Sinica.

Involvement of Kv1.5 Protein in Oxidative Vascular Endothelial Cell Injury

J. Li, Y. Guan, Ying Xiao, 2012, PloS one.

Smooth muscle-specific TMEM16A expression protects against angiotensin II-induced cerebrovascular remodeling via suppressing extracellular matrix deposition.

Y. Guan, M. Ma, Xiao-fei Lv, 2019, Journal of molecular and cellular cardiology.

Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2012, Circulation.

Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2012, Circulation.

Endophilin A2 protects H2O2-induced apoptosis by blockade of Bax translocation in rat basilar artery smooth muscle cells.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2016, Journal of molecular and cellular cardiology.

Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2011, Atherosclerosis.

ClC-3 chloride channel prevents apoptosis induced by thapsigargin in PC12 cells

Y. Guan, H.-N. Zhang, J.‐G. Zhou, 2006, Apoptosis.

Deficiency of volume-regulated ClC-3 chloride channel attenuates cerebrovascular remodelling in DOCA-salt hypertension.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2013, Cardiovascular research.

Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway

Y. Guan, Hong-Shuo Sun, Jian Cheng, 2017, Acta Pharmacologica Sinica.

TRPC3 channel confers cerebrovascular remodelling during hypertension via transactivation of EGF receptor signalling.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2016, Cardiovascular research.

Effects of 15-deoxy-∆ 12 , 14-prostaglandin J 2 on cell proliferation and apoptosis in ECV 304 endothelial cells 1

Y. Guan, He Jian-gui, Dan-dan Chen, 2003 .

ClC-3 deficiency protects preadipocytes against apoptosis induced by palmitate in vitro and in type 2 diabetes mice

J. Li, Y. Guan, Jie Du, 2014, Apoptosis.

Alteration of Volume-Regulated Chloride Movement in Rat Cerebrovascular Smooth Muscle Cells During Hypertension

Jia-guo Zhou, Y. Guan, Guan-lei Wang, 2007, Hypertension.

Volume‐regulated chloride channels and cerebral vascular remodelling

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2010, Clinical and experimental pharmacology & physiology.

Silence of ClC‐3 chloride channel inhibits cell proliferation and the cell cycle via G1/S phase arrest in rat basilar arterial smooth muscle cells

Y. Guan, J.‐G. Zhou, Q. Qiu, 2008, Cell proliferation.

Platelet CFTR inhibition enhances arterial thrombosis via increasing intracellular Cl− concentration and activation of SGK1 signaling pathway

Jun Yu Li, J. Li, Y. Guan, 2022, Acta Pharmacologica Sinica.

Suppression of Kv1.5 protects against endothelial apoptosis induced by palmitate and in type 2 diabetes mice

Y. Guan, Hong-Shuo Sun, Jie Du, 2017, Life sciences.

ClC-3 chloride channel/antiporter defect contributes to inflammatory bowel disease in humans and mice

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2014, Gut.

Transmembrane member 16A participates in hydrogen peroxide‐induced apoptosis by facilitating mitochondria‐dependent pathway in vascular smooth muscle cells

Y. Guan, M. Ma, Xiao-fei Lv, 2018, British journal of pharmacology.

ClC-3 deficiency prevents atherosclerotic lesion development in ApoE-/- mice.

Jia-guo Zhou, Y. Guan, J. Tao, 2015, Journal of molecular and cellular cardiology.

Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2011, European journal of pharmacology.

Xyloketal B Exhibits Its Antioxidant Activity through Induction of HO-1 in Vascular Endothelial Cells and Zebrafish

J. Li, Y. Guan, Huan-xing Su, 2013, Marine drugs.

Ginsenoside Rd prevents glutamate‐induced apoptosis in rat cortical neurons

Xiao-yan Li, Yongbo Tang, Jia-guo Zhou, 2010, Clinical and experimental pharmacology & physiology.

Interaction between Cl− channels and CRAC-related Ca2+ signaling during T lymphocyte activation and proliferation

Y. Guan, Guan-lei Wang, Q. Qiu, 2006, Acta Pharmacologica Sinica.

Deficiency in ClC-3 Chloride Channels Prevents Rat Aortic Smooth Muscle Cell Proliferation

Y. Guan, Guan-lei Wang, Mo-Jun Lin, 2002, Circulation research.

ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2011, Apoptosis.

ClC-3 deficiency prevents apoptosis induced by angiotensin II in endothelial progenitor cells via inhibition of NADPH oxidase

Jie Liu, Y. Guan, Lei Li, 2013, Apoptosis.

Comparison of the Ca2+ movement by activation of alpha1-adrenoceptor subtypes in HEK-293 cells.

Y. Guan, H. He, C. Han, 1997, Life sciences.

TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase–Derived Reactive Oxygen Species Generation in Hypertension

Jia-guo Zhou, Y. Guan, M. Ma, 2017, Hypertension.

Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl− concentration

Y. Guan, Xin Zeng, Yanhua Du, 2021, British journal of pharmacology.

TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner

Y. Guan, Xiao-fei Lv, Cheng-cui Huang, 2021, Acta Pharmaceutica Sinica. B.

Ca2+/Calmodulin-Dependent Protein Kinase II γ-Dependent Serine727 Phosphorylation Is Required for TMEM16A Ca2+-Activated Cl- Channel Regulation in Cerebrovascular Cells.

Jia-guo Zhou, Y. Guan, M. Ma, 2017, Circulation journal : official journal of the Japanese Circulation Society.

Stroke Downregulation of TMEM 16 A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2012 .

Simvastatin Attenuated Cerebrovascular Cell Proliferation in the Development of Hypertension Through Rho/Rho-kinase Pathway

Y. Guan, M. Ma, Shi-yang Li, 2012, Journal of cardiovascular pharmacology.

Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells.

Ren-Hong Du, Y. Guan, Hong-Shuo Sun, 2016, Circulation journal : official journal of the Japanese Circulation Society.

CFTR Suppresses Neointimal Formation Through Attenuating Proliferation and Migration of Aortic Smooth Muscle Cells

Yongbo Tang, Y. Guan, Hong-Shuo Sun, 2022, Journal of cardiovascular pharmacology.

WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells

Y. Guan, M. Ma, Lu Sun, 2017, Acta Pharmacologica Sinica.

Regulation of Intracellular Cl- Concentration through Volume-regulated ClC-3 Chloride Channels in A10 Vascular Smooth Muscle Cells*

Jia-guo Zhou, Y. Guan, Q. Qiu, 2005, Journal of Biological Chemistry.

Ginsenoside-Rd from panax notoginseng blocks Ca2+ influx through receptor- and store-operated Ca2+ channels in vascular smooth muscle cells.

Jia-guo Zhou, Y. Guan, Guan-lei Wang, 2006, European journal of pharmacology.

Effects of Rb1 from the Panax notoginseng saponins on arrhythmia and Ca2+ movement in rat heart cells

Y. Guan, L. Miao, Jianfang Sun, 1996 .

Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice

Y. Guan, Hong-Shuo Sun, Ming-ming Ma, 2019, Acta Pharmacologica Sinica.

Increased intracellular Cl− concentration mediates neutrophil extracellular traps formation in atherosclerotic cardiovascular diseases

Y. Guan, Ruomei Wang, Hui-Jing Han, 2022, Acta Pharmacologica Sinica.

TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation

Jia-guo Zhou, Y. Guan, M. Ma, 2020, Theranostics.

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells

Y. Guan, M. Ma, Xiao-fei Lv, 2014, Apoptosis.

Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2013, Apoptosis.

Ginsenoside-Rd, a new voltage-independent Ca2+ entry blocker, reverses basilar hypertrophic remodeling in stroke-prone renovascular hypertensive rats.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2009, European journal of pharmacology.

Characteristic of Cl− current induced by ATP in bovine aortic endothelial cells

Y. Guan, Wenlin Wei, Hua He, 2003 .

SGK1 mediates the hypotonic protective effect against H2O2-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway

Y. Guan, M. Ma, Xiao-fei Lv, 2020, Acta Pharmacologica Sinica.

Decrease of Intracellular Chloride Concentration Promotes Endothelial Cell Inflammation by Activating Nuclear Factor-&kgr;B Pathway

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2012, Hypertension.

The effects of EGTA on vascular smooth muscle contractility in calcium-free medium.

E. Daniel, Y. Guan, C. Kwan, 1988, Canadian journal of physiology and pharmacology.

A novel marine compound xyloketal B protects against oxidized LDL-induced cell injury in vitro.

Zhong Pei, Y. Guan, Shengping Chen, 2009, Biochemical pharmacology.

Xyloketal B Suppresses Glioblastoma Cell Proliferation and Migration in Vitro through Inhibiting TRPM7-Regulated PI3K/Akt and MEK/ERK Signaling Pathways

J. Rutka, Y. Guan, Zhong-Ping Feng, 2015, Marine drugs.

Ginsenoside-Rd, a purified component from panax notoginseng saponins, prevents atherosclerosis in apoE knockout mice.

J. Li, Yongbo Tang, Jia-guo Zhou, 2011, European journal of pharmacology.

Effects of Scutellarein on diabetic rat aorta.

Y. Guan, H. He, B. Zhu, 2000, Acta pharmacologica Sinica.

Vinpocetine inhibits breast cancer cells growth in vitro and in vivo

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2012, Apoptosis.

SGK1 mediates hypotonic challenge-induced proliferation in basilar artery smooth muscle cells via promoting CREB signaling pathway.

Y. Guan, M. Ma, Fengxian Lu, 2021, European journal of pharmacology.

Drought-resistant rice: physiological framework for an integrated research strategy

R. Serraj, V. Gowda, R. Torres, 2009 .

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells

Y. Guan, M. Ma, Xiao-fei Lv, 2014, Apoptosis.

IN VITRO INHIBITORY EFFECTS OF CHEUBULINIC ACID ON THE CONTRACTILE RESPONSES OF CARDIOVASCULAR MUSCLES

Y. Guan, Juei-Tang Cheng, C. Kwan, 1996, Clinical and experimental pharmacology & physiology.

[Effect of the total saponins of Panax notogiseng on contraction of rabbit aortic strips].

Y. Guan, H. He, J. X. Chen, 1985, Zhongguo yao li xue bao = Acta pharmacologica Sinica.

Tetrandrine is not a selective calcium channel blocker in vascular smooth muscle.

Y. Guan, C. Kwan, H. Deng, 1992, Zhongguo yao li xue bao = Acta pharmacologica Sinica.

LRRC8A is essential for volume‐regulated anion channel in smooth muscle cells contributing to cerebrovascular remodeling during hypertension

Y. Guan, Xiao-fei Lv, Ming-ming Ma, 2021, Cell proliferation.

Threonine532 phosphorylation in ClC‐3 channels is required for angiotensin II‐induced Cl− current and migration in cultured vascular smooth muscle cells

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2016, British journal of pharmacology.

Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation.

Yongbo Tang, Jia-guo Zhou, Y. Guan, 2016, Atherosclerosis.

Upregulation of TRPM 7 Channels by Angiotensin II Triggers Phenotypic Switching of Vascular Smooth Muscle Cells of Ascending Aorta

Yongbo Tang, Y. Guan, Zheng Zhang, 2012 .

Endothelium-Specific GTP Cyclohydrolase I Overexpression Attenuates Blood Pressure Progression in Salt-Sensitive Low-Renin Hypertension

N. Alp, K. Channon, Y. Guan, 2008, Circulation.

Contractile responses of diabetic rat aorta to phenylephrine at different stages of diabetic duration.

Y. Guan, H. He, B. Zhu, 2001, Acta pharmacologica Sinica.

Alpha-adrenoceptors in vascular smooth muscle: all is not well.

E. Daniel, Y. Guan, C. Kwan, 1991, Blood & Vessel.

Does in vitro activation of postsynaptic alpha 2-adrenoceptor utilize intracellular Ca2+ for contraction in dog saphenous vein?

E. Daniel, Y. Guan, C. Kwan, 1989, Canadian Journal of Physiology and Pharmacology.

Evidence against the role of alpha 1-adrenoceptor reserve in buffering the inhibitory effect of nifedipine on the contractility of canine vascular smooth muscle.

E. Daniel, Y. Guan, C. Kwan, 1990, Canadian journal of physiology and pharmacology.

ClC-3 promotes angiotensin II-induced reactive oxygen species production in endothelial cells by facilitating Nox2 NADPH oxidase complex formation

Y. Guan, Yanhua Du, Yue-jiao Li, 2018, Acta Pharmacologica Sinica.

The ClC-3 Cl- channel in cell volume regulation, proliferation and apoptosis in vascular smooth muscle cells.

Y. Guan, Yong-Yuan Guan, Guan-Lei Wang, 2006, Trends in pharmacological sciences.

Differences between femoral artery and vein smooth muscle cells in volume-regulated chloride channels.

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2012, Canadian journal of physiology and pharmacology.

Vinpocetine inhibits breast cancer cells growth in vitro and in vivo

Y. Guan, Yong Tang, Zheng Zhang, 2012, Apoptosis.

Ginsenoside-Rd potentiates apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through the mitochondrial pathway

Yongbo Tang, Y. Guan, Yun Liu, 2012, Apoptosis.

Cellular mechanisms of reduced sarcoplasmic reticulum Ca2+ content in L-thyroxin-induced rat ventricular hypertrophy

Y. Guan, Jing-hua Ou, Jie Liu, 2008, Acta Pharmacologica Sinica.

Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation

Y. Guan, M. Ma, Xiao-fei Lv, 2019, Acta Pharmacologica Sinica.

ClC-3 deficiency protects preadipocytes against apoptosis induced by palmitate in vitro and in type 2 diabetes mice

J. Li, Y. Guan, Jie Du, 2014, Apoptosis.

Integrin β3 mediates cerebrovascular remodelling through Src/ClC‐3 volume‐regulated Cl− channel signalling pathway

Y. Guan, M. Ma, Xiao-fei Lv, 2014, British journal of pharmacology.

Tyrosine 284 phosphorylation is required for ClC-3 chloride channel activation in vascular smooth muscle cells.

Yongbo Tang, Y. Guan, J. Tao, 2013, Cardiovascular research.

Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells

Yongbo Tang, Y. Guan, Yun Liu, 2013, Apoptosis.

ClC-3 promotes angiotensin II-induced reactive oxygen species production in endothelial cells by facilitating Nox2 NADPH oxidase complex formation

Y. Guan, Yanhua Du, Yue-jiao Li, 2018, Acta Pharmacologica Sinica.

ClC-3 deficiency prevents apoptosis induced by angiotensin II in endothelial progenitor cells via inhibition of NADPH oxidase

Jie Liu, Y. Guan, Jing Liu, 2013, Apoptosis.

Effects of Cl- channel blockers on endothelin-1-induced proliferation of rat vascular smooth muscle cells.

Y. Guan, Guixiu Xiao, Hua He, 2002, Life sciences.

Erigeron breviscapus prevents defective endothelium-dependent relaxation in diabetic rat aorta.

Y. Guan, H. He, B. Zhu, 1999, Life sciences.

Simvastatin Ameliorates Rat Cerebrovascular Remodeling During Hypertension via Inhibition of Volume-Regulated Chloride Channel

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2010, HYPERTENSION.

Multiple potassium conductances at the mammalian motor nerve terminal

D. Saint, Y. Guan, D. Quastel, 1987, Pflügers Archiv - European Journal of Physiology.

Multiple actions of cadmium on transmitter release at the mouse neuromuscular junction.

D. Saint, Y. Guan, D. Quastel, 1987, Canadian journal of physiology and pharmacology.

ClC-3 chloride channel/antiporter defect contributes to inflammatory bowel disease in humans and mice

Yongbo Tang, Y. Guan, R. Pang, 2014, Gut.

Decrease of Intracellular Chloride Concentration Promotes Endothelial Cell Inflammation by Activating Nuclear Factor-&kgr;B Pathway

Yongbo Tang, Y. Guan, J. Tao, 2012, Hypertension.

Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2012, Circulation.

Silence of ClC‐3 chloride channel inhibits cell proliferation and the cell cycle via G1/S phase arrest in rat basilar arterial smooth muscle cells

Y. Guan, J.‐G. Zhou, Q. Qiu, 2008, Cell proliferation.

Upregulation of TRPM7 Channels by Angiotensin II Triggers Phenotypic Switching of Vascular Smooth Muscle Cells of Ascending Aorta

Yongbo Tang, Y. Guan, Zheng Zhang, 2012, Circulation research.

Alteration of Volume-Regulated Chloride Movement in Rat Cerebrovascular Smooth Muscle Cells During Hypertension

Y. Guan, Guan-lei Wang, Zheng Zhang, 2007, Hypertension.

Simvastatin Ameliorates Rat Cerebrovascular Remodeling During Hypertension via Inhibition of Volume-Regulated Chloride Channel

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2010, Hypertension.

Differences between femoral artery and vein smooth muscle cells in volume-regulated chloride channels.

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2012, Canadian journal of physiology and pharmacology.

Blood Vessels Simvastatin Ameliorates Rat Cerebrovascular Remodeling during Hypertension via Inhibition of Volume-regulated Chloride Channel Materials and Methods

Yongbo Tang, Y. Guan, Xiao-fei Lv, 2022 .

Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway.

Y. Guan, Xiao-fei Lv, Cheng-cui Huang, 2024, Acta pharmacologica Sinica.