A. Asaithamby

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Cellular responses to DNA double-strand breaks after low-dose γ-irradiation

David J. Chen, Aroumougame Asaithamby, A. Asaithamby, 2009, Nucleic acids research.

Evaluating biomarkers to model cancer risk post cosmic ray exposure

Leif E. Peterson, Yared H. Kidane, A. Snijders, 2016, Life sciences in space research.

Unrepaired clustered DNA lesions induce chromosome breakage in human cells

David J. Chen, Aroumougame Asaithamby, David J Chen, 2011, Proceedings of the National Academy of Sciences.

RAD51 interconnects between DNA replication, DNA repair and immunity

E. Wakeland, A. Asaithamby, I. Dozmorov, 2017, Nucleic acids research.

New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress.

Benjamin P. C. Chen, A. Asaithamby, Mengxia Li, 2012, Cancer letters.

Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.

A. Asaithamby, S. Mukherjee, Kalayarasan Srinivasan, 2019, Advances in protein chemistry and structural biology.

Nuclear Foci Assays in Live Cells.

A. Asaithamby, Eiichiro Mori, 2019, Methods in molecular biology.

Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture

David J. Chen, J. Minna, O. Delgado, 2011, Nucleic acids research.

Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression

J. McDonald, A. Asaithamby, Joseph A. Hill, 2020, Nature Metabolism.

Repair of HZE-Particle-Induced DNA Double-Strand Breaks in Normal Human Fibroblasts

David J. Chen, M. Story, S. Burma, 2008, Radiation research.

WRN Exonuclease Structure, Molecular Mechanism, and DNA End Processing Role

David J. Chen, J. Tainer, Lauren G. Holden, 2006 .

Carbon Ion Radiotherapy in the Management of Hepatocellular Carcinoma

C. Hallemeier, J. Ashman, A. Asaithamby, 2021, Journal of hepatocellular carcinoma.

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

Paul M. Rindler, David J. Chen, M. Giacca, 2014, Cell.

Hypoxia induces heart regeneration in adult mice

Diana C. Canseco, R. Deberardinis, A. Shah, 2016, Nature.

Isolation of time dependent DNA damage induced by energetic carbon ions and their fragments using fluorescent nuclear track detectors.

A. Abdollahi, A. Asaithamby, S. Greilich, 2019, Medical physics.

Werner Syndrome Protein and DNA Replication

A. Asaithamby, S. Mukherjee, Kalayarasan Srinivasan, 2018, International journal of molecular sciences.

Transcriptional elongation requires DNA break-induced signalling Harvard made this article openly available. Please share how this access benefits you. Your story matters

B. Chen, Yaoyu E. Wang, A. Asaithamby, 2015 .

Knock-down of CLOCK in the VTA through RNAi results in a mixed state of mania and depression-like behavior

Laurent Coque, A. Asaithamby, S. Mukherjee, 2011 .

FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

A. Asaithamby, S. Mukherjee, Burong Hu, 2015, Cell cycle.

Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes

A. Asaithamby, S. Mukherjee, L. Szweda, 2021, Proceedings of the National Academy of Sciences.

Time-Lapse Monitoring of DNA Damage Colocalized With Particle Tracks in Single Living Cells.

A. Asaithamby, G. Sawakuchi, N. Sahoo, 2016, International journal of radiation oncology, biology, physics.

MDC1 Regulates DNA-PK Autophosphorylation in Response to DNA Damage*

David J. Chen, B. Chen, Junjie Chen, 2004, Journal of Biological Chemistry.

DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy.

A. Asaithamby, T. Gillette, Joseph A. Hill, 2019, Circulation.

Pancreatic cancer patients with germline BRCA mutations can benefit from olaparib treatment

A. Asaithamby, S. Mukherjee, 2020, Translational cancer research.

Understanding Cancer Development Processes after HZE-Particle Exposure: Roles of ROS, DNA Damage Repair and Inflammation

F. A. Cucinotta, A. Snijders, S. Costes, 2015, Radiation research.

Ionizing radiation and heart risks.

A. Asaithamby, Souparno Bhattacharya, 2016, Seminars in cell & developmental biology.

Proximity within interphase chromosome contributes to the breakpoint distribution in radiation-induced intrachromosomal exchanges

David J. Chen, M. Hada, A. Asaithamby, 2014 .

Ku recruits XLF to DNA double‐strand breaks

David J. Chen, A. Asaithamby, Ken-ichi Yano, 2008, EMBO reports.

Immunomodulatory Effects of Radiotherapy

A. Asaithamby, S. Mukherjee, S. Kumari, 2020, International journal of molecular sciences.

RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR

P. Wright, M. Kelliher, R. Paulmurugan, 2008, Cell Death and Differentiation.

The Major DNA Repair Pathway after Both Proton and Carbon-Ion Radiation is NHEJ, but the HR Pathway is More Relevant in Carbon Ions

Takeji Sakae, Koji Tsuboi, Takaaki Ishikawa, 2015, Radiation research.

Transcriptional elongation requires DNA break-induced signalling

Benjamin P. C. Chen, Yaoyu E. Wang, A. Asaithamby, 2015, Nature Communications.

Knockdown of Clock in the Ventral Tegmental Area Through RNA Interference Results in a Mixed State of Mania and Depression-Like Behavior

Laurent Coque, C. McClung, S. Birnbaum, 2010, Biological Psychiatry.

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments

Benjamin P. C. Chen, Arun Gupta, A. Asaithamby, 2016, Nucleic acids research.

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway

David J. Chen, A. Asaithamby, S. Mukherjee, 2015, Oncotarget.

Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase

J. Shay, A. Asaithamby, S. Mukherjee, 2020, The Journal of Biological Chemistry.

Corrigendum: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

Diana C. Canseco, J. Richardson, Zhigang Lu, 2015, Nature.

Progesterone Receptor Expression in Medroxyprogesterone Acetate-Induced Murine Mammary Carcinomas and Response to Endocrine Treatment

A. Asaithamby, A. Molinolo, G. Shyamala, 2003, Breast Cancer Research and Treatment.

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

David J. Chen, J. Tainer, Lauren G. Holden, 2006, Nature Structural &Molecular Biology.

WRN participates in translesion synthesis pathway through interaction with NBS1

David J. Chen, B. Chen, K. Tanimoto, 2010, Mechanisms of Ageing and Development.

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.

David J. Chen, Aroumougame Asaithamby, David J Chen, 2011, Mutation research.

MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

T. Ludwig, T. Pandita, C. Hunt, 2014, Cell reports.

Cell Cycle Dependence of DNA-dependent Protein Kinase Phosphorylation in Response to DNA Double Strand Breaks*

David J. Chen, B. Chen, D. Chan, 2005, Journal of Biological Chemistry.

Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity*

David J. Chen, J. Tainer, J. Perry, 2010, The Journal of Biological Chemistry.

NBS1-CtIP–Mediated DNA End Resection Regulates cGAS Binding to Micronuclei

A. Asaithamby, S. Mukherjee, Janice Ortega, 2020, bioRxiv.

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells

Sylvain V Costes, Teresa Neumaier, Mina J Bissell, 2011, Proceedings of the National Academy of Sciences.

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy.

A. Asaithamby, Souparno Bhattacharya, 2017, Translational cancer research.

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

Paul M. Rindler, David J. Chen, M. Giacca, 2014, Cell.

Non-homologous end joining is more important than proton linear energy transfer in dictating cell death.

R. Mohan, Pavel Sumazin, A. Asaithamby, 2019, International journal of radiation oncology, biology, physics.

Human ventricular unloading induces cardiomyocyte proliferation.

Diana C. Canseco, Sandeep R. Das, A. Asaithamby, 2015, Journal of the American College of Cardiology.

COMT val158met polymorphism and molecular alterations in the human dorsolateral prefrontal cortex: Differences in controls and in schizophrenia

C. Tamminga, B. Adams-Huet, A. Shukla, 2016, Schizophrenia Research.

Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression

J. McDonald, A. Asaithamby, P. Shaul, 2020, Nature Metabolism.

Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.

David J. Chen, J. Kobayashi, A. Asaithamby, 2014, Cell reports.

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

Diana C. Canseco, A. Asaithamby, F. Hou, 2015, Nature.

MDC 1 Regulates DNA-PK Autophosphorylation in Response to DNA Damage *

David J. Chen, B. Chen, Junjie Chen, 2004 .