Mary Beth Hilton

发表

p21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.

P. Kaldis, A. Satyanarayana, Mary Beth Hilton, 2008, Molecular biology of the cell.

Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116.

Todd M Umstead, Lino Tessarollo, Kunio Nagashima, 2013, Cell reports.

GPR124 functions as a WNT7-specific coactivator of canonical β-catenin signaling.

S. Seaman, J. Rubin, Mary Beth Hilton, 2015, Cell reports.

TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types.

P. Lemotte, S. Seaman, S. Saha, 2012, Cancer cell.

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier

K. Nagashima, S. Seaman, L. Tessarollo, 2011, Proceedings of the National Academy of Sciences.

Host-derived tumor endothelial marker 8 promotes the growth of melanoma.

S. Seaman, L. Tessarollo, Mary Beth Hilton, 2009, Cancer research.

COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

Nimit L. Patel, Timothy D. Veenstra, Thomas P. Conrads, 2014, Science Translational Medicine.

Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53

P. Kaldis, Mary Beth Hilton, E. Aleem, 2009, Molecular and Cellular Biology.

Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition

P. Kaldis, Mary Beth Hilton, Shuhei Kotoshiba, 2009, Proceedings of the National Academy of Sciences.

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.

D. Dimitrov, S. Seaman, C. Szot, 2017, Cancer cell.

Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.

P. Kaldis, Mary Beth Hilton, H. Kiyokawa, 2006, Developmental cell.

Tumor stroma‐targeted antibody‐drug conjugate triggers localized anticancer drug release

D. Dimitrov, S. Seaman, C. Szot, 2018, The Journal of clinical investigation.

Cancer cell survival depends on collagen uptake into tumor-associated stroma

D. Dimitrov, S. Seaman, C. Szot, 2022, Nature Communications.

Anti-CD 276-drug conjugates display potent anti-tumor and anti-metastatic activity d Pyrrolobenzodiazepine dimers are optimal warheads for targeting tumor

D. Dimitrov, S. Seaman, C. Szot, 2022 .

TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types.

P. Lemotte, S. Seaman, Mary Beth Hilton, 2012, Cancer cell.

Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

Nimit L. Patel, D. Dimitrov, S. Seaman, 2023, Cell reports.