J. Ward

发表

A new method for introducing double-strand breaks into cellular DNA.

C. Limoli, J. Ward, 1993, Radiation research.

Radiation-Dependent Limit for the Viability of Bacterial Spores in Halite Fluid Inclusions and on Mars

J. Bada, K. Pogliano, J. Ward, 2003, Radiation research.

Complexity of damage produced by ionizing radiation.

J. Ward, 2000, Cold Spring Harbor symposia on quantitative biology.

DNA strand break yields after post-high LET irradiation incubation with endonuclease-III and evidence for hydroxyl radical clustering

C. Limoli, J. Ward, J. Milligan, 2001, International journal of radiation biology.

Radiation Chemistry at the DNA Level-A Radiation Study Section Workshop1

R. Osman, J. Ward, P. Doetsch, 1997 .

Equilibrium dialysis studies of the binding of radioprotector compounds to DNA.

J. Ward, R. C. Fahey, G. Smoluk, 1986, Radiation research.

Effects of postirradiation temperature on the yields of radiation-induced single- and double-strand breakage in SV40 DNA.

J. Ward, G. D. Jones, T. Boswell, 1994, Radiation research.

The radiation-induced lesions which trigger the bystander effect.

J. Ward, 2002, Mutation research.

The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review.

J. Ward, John F. Ward, 1990, International journal of radiation biology.

Mechanisms of radiosensitization in bromodeoxyuridine-substituted cells.

J. Ward, J. Aguilera, G. D. Jones, 1993, International journal of radiation biology.

Mechanisms of radiosensitization in iododeoxyuridine-substituted cells.

C. Limoli, J. Ward, J. Aguilera, 1995, International journal of radiation biology.

Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals.

J. Ward, 1981, Radiation research.

Yield of strand breaks as a function of scavenger concentration and LET for SV40 irradiated with 4He ions.

J. Ward, J. Milligan, J. Aguilera, 1993, Radiation research.

The difference that linear energy transfer makes to precursors of DNA strand breaks.

J. Ward, J. Milligan, J. Aguilera, 1996, Radiation research.

DNA strand-break yields after post-irradiation incubation with base excision repair endonucleases implicate hydroxyl radical pairs in double-strand break formation.

J. Ward, T. Nguyen, J. Milligan, 2000, International journal of radiation biology.

Biological Consequences of Non-Homogeneous Energy Deposition by Ionising Radiation

J. Ward, J. Milligan, G. Jones, 1994 .

Yield of single-strand breaks due to attack on DNA by scavenger-derived radicals.

J. Ward, J. Milligan, 1994, Radiation research.

Radiobiology of ultrasoft X rays. V. Modification of cell inactivation by dimethyl sulfoxide.

D. Goodhead, J. Ward, M. E. Schillaci, 1996, Radiation research.

Methylperoxyl radicals as intermediates in the damage to DNA irradiated in aqueous dimethyl sulfoxide with gamma rays.

R. Cunningham, J. Ward, S. Wallace, 1996, Radiation research.

SEROLOGIC ASSAY OF DNA BASE DAMAGE

J. Ward, H. L. Lewis, 1978 .

Radiosensitization of Chinese hamster V79 cells by bromodeoxyuridine substitution of thymidine: enhancement of radiation-induced toxicity and DNA strand break production by monofilar and bifilar substitution.

J. Ward, L. Ling, Lucy L. Ling, 1990, Radiation research.

Radioprotection of plasmid DNA by oligolysines

J. Ward, G. Newton, J. Milligan, 2004, International journal of radiation biology.

Repair of oxidative DNA damage by amino acids.

J. Ward, J. Milligan, J. Aguilera, 2003, Nucleic acids research.

One-electron oxidation of plasmid DNA by selenium(V) species

J. Ward, J. Milligan, J. Aguilera, 2002, International journal of radiation biology.

Redox reactivity of guanyl radicals in plasmid DNA.

J. Ward, J. Milligan, J. Aguilera, 2001, International journal of radiation biology.

Mechanism of DNA damage by thiocyanate radicals.

J. Ward, J. Milligan, J. Aguilera, 2000, International journal of radiation biology.

Yield of DNA strand breaks after base oxidation of plasmid DNA.

R. Cunningham, J. Ward, T. Nguyen, 1999, Radiation research.

Effect of hydroxyl radical scavenging capacity on clustering of DNA damage.

J. Ward, T. Nguyen, J. Milligan, 1997, Radiation research.

Characterization of the reaction rate coefficient of DNA with the hydroxyl radical.

J. Ward, J. Milligan, J. Aguilera, 1996, Radiation research.

DNA repair by thiols in air shows two radicals make a double-strand break.

J. Ward, R. C. Fahey, J. Milligan, 1995, Radiation research.

Make a Double-Strand Break

J. Ward, J. Milligan, J. Aguilera, 1995 .

Aerobic radioprotection of pBR322 by thiols: effect of thiol net charge upon scavenging of hydroxyl radicals and repair of DNA radicals.

J. Ward, G. Newton, R. C. Fahey, 1992, Radiation research.

Thiol uptake by Chinese hamster V79 cells and aerobic radioprotection as a function of the net charge on the thiol.

J. Ward, G. Newton, R. C. Fahey, 1992, Radiation research.

Reaction of guanyl radicals in plasmid DNA with biological reductants: chemical repair of DNA damage produced by the direct effect of ionizing radiation

J. Ward, J. Milligan, J. Aguilera, 2001, International journal of radiation biology.

Redox equilibrium between guanyl radicals and thiocyanate influences base damage yields in gamma irradiated plasmid DNA. Estimation of the reduction potential of guanyl radicals in plasmid DNA in aqueous solution at physiological ionic strength

J. Ward, J. Milligan, J. Aguilera, 2001, International journal of radiation biology.

Time-dose relationships for 5-fluorouracil cytotoxicity against human epithelial cancer cells in vitro.

J. Ward, J. Byfield, P. Calabro-Jones, 1982, Cancer research.

Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug.

J. Ward, R. C. Fahey, J. Aguilera, 1988, Cancer research.

Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721.

J. Ward, R. C. Fahey, G. Smoluk, 1985, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Pyrimidine dimer induction in E. coli DNA by Cerenkov emission associated with high energy X-irradiation.

J. Redpath, J. Ward, T. Morgan, 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.

A quantitative assay of deoxyribonucleic acid strand breaks and their repair in mammalian cells.

J. Ward, W. Blakely, E. I. Joner, 1982, Analytical biochemistry.

Radioimmunoassay of 7,8-dihydro-8-oxoadenine (8-hydroxyadenine).

J. Ward, G. J. West, I. W. West, 1982, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Radioimmunoassay of a thymine glycol.

J. Ward, G. J. West, I. W. West, 1982, Radiation Research.

Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents

J. Murnane, J. Ward, J. Byfield, 1980, Nature.

DNA damage and repair.

J. Ward, 1991, Basic life sciences.

Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.

J. Murnane, J. Ward, J. Byfield, 1981, British Journal of Cancer.

Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection.

J. Ward, R. C. Fahey, J. Aguilera, 1988, Cancer research.

Strand breaks, base release, and postirradiation changes in DNA gamma-irradiated in dilute O2-saturated aqueous solution.

J. Ward, I. Kuo, 1976, Radiation research.

DNA Polymerase a and Activity in ?-irradiated HeLa S3 Cells

J. Ward, S. Leadon, 1981 .

Molecular mechanisms of radiation-induced damage to nucleic acids

J. Ward, 1975 .

Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei.

J. Ward, G. Newton, R. C. Fahey, 1996, Radiation research.

Radiation damage to DNA in aqueous solution: a comparison of the response of the single-stranded form with that of the double-stranded form.

J. Ward, I. Kuo, 1978, Radiation research.

γ-irradiation of Aqueous Solutions of Polynucleotides

J. Ward, M. Urist, 1967 .

Mechanisms of DNA repair and their potential modification for radiotherapy.

J. Ward, John F. Ward, 1986, International journal of radiation oncology, biology, physics.

Enhancement of human tumor cell killing by L-canavanine in combination with gamma-radiation.

M. Green, J. Ward, 1983, Cancer research.

Electron spin resonance studies of free radicals in irradiated single crystals of 5-methylcytosine

J. Ward, J. Hüttermann, L. S. Myers, 1971 .

Electron spin resonance studies of free radicals formed from orotic acid.

J. Ward, J. Hüttermann, L. S. Myers, 1970, The Journal of physical chemistry.

SYMPOSIUM ON RADICAL PROCESSES IN RADIOBIOLOGY AND CARCINOGENESIS Some Biochemical Consequences of the Spatial Distribution of Ionizing Radiation-Produced Free Radicals1

J. Ward, 1981 .

Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. I. Pulse- and steady-state radiolysis of 5-bromouracil and thymine.

J. Ward, L. S. Myers, J. Zimbrick, 1969, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Electron spin resonance studies of free radicals formed from orotic acid.

J. Ward, J. Hüttermann, L. S. Myers, 1970, The Journal of physical chemistry.

Deoxynucleotides--models for studying mechanisms of strand breakage in DNA. II. Thymidine 3'5'-diphosphate.

J. Ward, I. Kuo, 1973, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Deoxynucleotides—models for studying mechanisms of strand breakage in DNA—I protection by sulphydryl compounds

J. Ward, 1971 .

Mechanism of the radiation-induced degradation of nucleic acids.

J. Ward, J. Weiss, G. Scholes, 1960, Journal of molecular biology.

Mechanisms of Radiation‐Induced Strand Break Formation in DNA

J. Ward, 1972 .

Site of Attack in the Radiolysis of Pyrimidine Compounds

J. Ward, L. S. Myers, D. E. Holmes, 1965, Nature.

Radiolysis of Thymine in Aqueous Solutions: Change in Site of Attack with Change in pH

J. Ward, L. S. Myers, D. E. Holmes, 1965, Science.

Radioprotection of DNA by thiols: relationship between the net charge on a thiol and its ability to protect DNA.

J. Ward, G. Newton, R. C. Fahey, 1988, Radiation research.

Oxygen Radicals in Biology and Medicine

John F. Ward, Clemens von Sonntag, J. Ward, 1988, Basic Life Sciences.

Radiation mutagenesis: the initial DNA lesions responsible.

J. Ward, 1995, Radiation research.

Derivatives : Form of the Drug Responsible for Protection Radioprotection of Cells in Culture by WR-2721 and Updated Version

J. Ward, R. C. Fahey, J. Aguilera, 2006 .

Enhancement of Human Tumor Cell Killing by L-Canavanine in Combination with -y-Radiation1

M. Green, J. Ward, 2006 .

DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability.

J. Ward, J F Ward, 1988, Progress in nucleic acid research and molecular biology.

Peptide repair of oxidative DNA damage.

J. Ward, J. Milligan, N. Tran, 2004, Biochemistry.

The effect of gamma-irradiated DNA on the activity of DNA polymerase.

J. Ward, S. Leadon, 1981, Radiation research.

Chemical Effects of Ionizing Radiations on Nucleic Acids and Nucleoproteins

J. Ward, G. Scholes, J. Weiss, 1960, Nature.

The complexity of DNA damage: relevance to biological consequences.

J. Ward, J F Ward, 1994, International journal of radiation biology.

Induction of lethal damage in E. coli by Cerenkov emission associated with high-energy X-rays: the effect of bromouracil substitution.

J. Redpath, J. Ward, T. Morgan, 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Serologic assay of DNA base damage. I. 5-Hydroxymethyldeoxyuridine, a radiation product of thymidine.

J. Ward, D. Muhleman, H. L. Lewis, 1978, Radiation research.

Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks.

D J Brenner, D. Brenner, J. Ward, 1992, International journal of radiation biology.

Determination of the acid dissociation constants for WR-1065 by proton NMR spectroscopy.

J. Ward, G. Newton, R. C. Fahey, 1992, Radiation research.

Photochemical production of uracil quantified in bromodeoxyuridine-substituted SV40 DNA by uracil DNA glycosylase and a lysyl-tyrosyl-lysine tripeptide.

C. Limoli, J. Ward, J. Milligan, 1997, Mutagenesis.

Some chemical effects of ionizing radiations on nucleic acids and related compounds

J. Ward, J. Weiss, G. Scholes, 1960 .

Transport of aminothiol radioprotectors into mammalian cells: passive diffusion versus mediated uptake.

J. Ward, G. Newton, R. C. Fahey, 1996, Radiation research.

Induction of Chromosome Aberrations and Delayed Genomic Instability by Photochemical Processes

J. Day, W. Morgan, C. Limoli, 1998, Photochemistry and photobiology.

Photochemical production of double-strand breaks in cellular DNA.

C. Limoli, J. Ward, 1995, Mutagenesis.

DNA damage in bromodeoxyuridine substituted SV40 DNA and minichromosomes following UVA irradiation in the presence of Hoechst dye 33258.

C. Limoli, J. Ward, 1994, International journal of radiation biology.

Response of bromodeoxyuridine-substituted Chinese hamster cells to UVA light exposure in the presence of Hoechst dye #33258: survival and DNA repair studies.

C. Limoli, J. Ward, 1994, Radiation research.

Biochemistry of DNA lesions.

J. Ward, J F Ward, 1985, Radiation research. Supplement.

Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues

John F. Ward, Christopher Logothetis, Jingjing Sun, 2009, Proceedings of the National Academy of Sciences.

Polyamine-induced compaction and aggregation of DNA--a major factor in radioprotection of chromatin under physiological conditions.

J A Aguilera, J. Ward, G. Newton, 1996, Radiation research.

Interaction of glutathione and other low-molecular-weight thiols with DNA: evidence for counterion condensation and coion depletion near DNA.

J. Ward, R. C. Fahey, G. Smoluk, 1988, Radiation research.

Nature of Lesions Formed by Ionizing Radiation

J. Ward, 1998 .

Effects of inhibitors of DNA strand break repair on HeLa cell radiosensitivity.

J. Ward, W. Blakely, E. I. Joner, 1982, Cancer research.

Critical target and dose and dose-rate responses for the induction of chromosomal instability by ionizing radiation.

W. Morgan, C. Limoli, J. Ward, 1999, Radiation research.

Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. II. Pulse- and steadystate radiolysis of bromouracil-substituted and unsubstituted DNA.

J. Ward, L. S. Myers, J. Zimbrick, 1969, International journal of radiation biology and related studies in physics, chemistry, and medicine.

DNA lesions and repair.

L. Mullenders, A. Natarajan, J. Ward, 1996, Mutation research.

The effect of superhelical density on the yield of single-strand breaks in gamma-irradiated plasmid DNA.

J. Ward, J. Milligan, A. D. Arnold, 1992, Radiation research.

Repair of oxidative guanine damage in plasmid DNA by indoles involves proton transfer between complementary bases.

J. Ward, J. Milligan, N. Tran, 2004, Biochemistry.

Action of Gamma-Irradiation on Dimethyl Uracil in Aqueous Solution in Absence of Oxygen

J. Ward, J. Weiss, G. Scholes, 1961, Science.

para-sulfobenzoyloxybromobimane: a new membrane-impermeable reagent useful for the analysis of thiols and their export from cells.

J. Ward, G. Newton, R. C. Fahey, 1992, Analytical biochemistry.

Abstract 4388: Combination therapy with anti-CTLA-4 plus leuprolide acetate in the pre-surgical setting of patients with regional, high-risk prostate cancer

P. Thall, P. Sharma, P. Troncoso, 2012 .

Basic Radiobiology

Nancy Oleinick, Stanley B. Curtis, Carmia Borek, 1988, American journal of clinical oncology.

Radiation and hydrogen peroxide induced free radical damage to DNA.

C. Limoli, J. Ward, P. Calabro-Jones, 1987, The British journal of cancer. Supplement.

Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide.

J. Ward, J F Ward, W. Blakely, 1985, Radiation research.

DNA damage as the cause of ionizing radiation-induced gene activation.

J. Ward, J F Ward, John F. Ward, 1994, Radiation research.

Monophosphate end groups produced in radiation-induced strand breakage in DNA.

J. Ward, E. Kay, 1977, Radiation research.

The effect of chloride ions on the gamma-radiation-induced destruction of DNA, nucleosides and nucleotides in aqueous solution.

J. Ward, I. Kuo, 1970, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution.

J A Aguilera, J. Ward, J. Milligan, 1993, Radiation research.

Track structure, chromosome geometry and chromosome aberrations.

D. Brenner, R. Sachs, J. Ward, 1994, Basic life sciences.

Ionizing Radiation Damage to DNA

J. Ward, 1999 .

A comparison of DNA damages produced under conditions of direct and indirect action of radiation.

M. Weinfeld, J. Ward, J. Milligan, 1994, International journal of radiation biology.

Effects of Inhibitors of DMA Strand Break Repair on HeLa Cell Radiosensitivity 1

J. Ward, W. Blakely, E. I. Joner, 2006 .

Radiolytic Damage to Genetic Material.

J. Ward, 1981 .

Mechanisms of Radiation Action on DNA in Model Systems - Their Relevance to Cellular DNA

J. Ward, 1991 .

Effect of polyamine-induced compaction and aggregation of DNA on the formation of radiation-induced strand breaks: quantitative models for cellular radiation damage.

J A Aguilera, J. Ward, G. Newton, 1997, Radiation research.

Radiation-induced strand breakage in DNA.

J. Ward, 1975, Basic life sciences.

Ionizing radiation induced DNA damage: identities and DNA repair.

J. Ward, 1986, Basic life sciences.

The limits to radioprotection of Chinese hamster V79 cells by WR-1065 under aerobic conditions.

J. Ward, R. C. Fahey, J. Aguilera, 1998, Radiation research.

Repair of guanyl radicals in plasmid DNA by electron transfer is coupled to proton transfer.

J. Ward, J. Milligan, J. Aguilera, 2004, Journal of the American Chemical Society.

Variation of single-strand break yield with scavenger concentration for the SV40 minichromosome irradiated in aqueous solution.

J. Ward, J. Milligan, J. Aguilera, 1993, Radiation research.

Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.

J. Murnane, J. Ward, T. DeAngelis, 1981, British Journal of Cancer.

On the mechanism of induction of photoreactivatable damage in E. coli by ionizing radiations.

J. Redpath, J. Ward, T. Morgan, 1982, International journal of radiation biology and related studies in physics, chemistry, and medicine.

A charge-coupled-device camera image analysis system for quantifying DNA distributions in agarose gels after pulsed-field gel electrophoresis.

W. Dewey, J. Ward, L. L. Thompson, 1994, Radiation research.

Radiation vs Chemical Damage to DNA

C. Limoli, J. Ward, P. Calabro-Jones, 1987 .