Tomas Åkerud

发表

Pharmacokinetics and the drug-target residence time concept.

G. Dahl, Tomas Åkerud, Göran Dahl, 2013, Drug discovery today.

Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.

Tomas Åkerud, N. Selmi, E. Hurt-Camejo, 2018, ACS medicinal chemistry letters.

Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function

A. Sabirsh, Tomas Åkerud, S. Martinsson, 2020, The Journal of Biological Chemistry.

Methyl group reorientation under ligand binding probed by pseudocontact shifts

M. Ubbink, Tomas Åkerud, Anneloes J. Blok, 2018, Journal of biomolecular NMR.

Intramolecular dynamics of low molecular weight protein tyrosine phosphatase in monomer-dimer equilibrium studied by NMR: a model for changes in dynamics upon target binding.

M. Akke, E. Thulin, Tomas Åkerud, 2002, Journal of molecular biology.

The Use of TrkA-PathHunter Assay in High-Throughput Screening to Identify Compounds That Affect Nerve Growth Factor Signaling

S. Trivedi, Tomas Åkerud, N. Dekker, 2013, Journal of biomolecular screening.

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

Tomas Åkerud, N. Selmi, K. Hallberg, 2018, ACS Medicinal Chemistry Letters.

Discovery of a novel pyrazole series of group X secreted phospholipase A2 inhibitor (sPLA2X) via fragment based virtual screening.

Tomas Åkerud, K. Hallberg, Hongming Chen, 2014, Bioorganic & medicinal chemistry letters.

Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling

Tomas Åkerud, P. Davidsson, A. Aagaard, 2018, The Journal of Biological Chemistry.

Automated Nano-Electrospray Mass Spectrometry for Protein-Ligand Screening by Noncovalent Interaction Applied to Human H-FABP and A-FABP

J. Roeraade, Tomas Åkerud, P. Edlund, 2003, Journal of biomolecular screening.

Interaction Applied to Human H-FABP and A-FABP Automated Nano-Electrospray Mass Spectrometry for Protein-Ligand Screening by Noncovalent

J. Roeraade, Tomas Åkerud, P. Edlund, 2013 .

Methyl group reorientation under ligand binding probed by pseudocontact shifts

M. Ubbink, Tomas Åkerud, Anneloes J. Blok, 2018, Journal of Biomolecular NMR.

Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation.

Johan Schultz, Stefan Svensson, Thomas Lundbäck, 2002, Journal of the American Chemical Society.