D. Siwak

发表

A module of negative feedback regulators defines growth factor signaling

Eytan Domany, Gideon Rechavi, Uri Alon, 2007, Nature Genetics.

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition.

Laura M. Heiser, Nicholas J. Wang, P. Spellman, 2009, Cancer research.

KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2

X. Zang, D. Siwak, A. Tari, 2004, Clinical & Experimental Metastasis.

"Mitotic drive" of expanded CTG repeats in myotonic dystrophy type 1 (DM1).

N H Terry, T. Ashizawa, M. Meistrich, 2001, Human molecular genetics.

Proteomic Profiling Identifies Pathways Dysregulated in Non-small Cell Lung Cancer and an Inverse Association of AMPK and Adhesion Pathways with Recurrence

K. Coombes, G. Mills, Jing Wang, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

G. Mills, M. Carey, B. Hennessy, 2009, Journal of oncology.

Analysis of mutational and proteomic heterogeneity of gastric cancer suggests an effective pipeline to monitor post-treatment tumor burden using circulating tumor DNA

G. Mills, L. Liotta, S. Nishizuka, 2020, PloS one.

Frequent post-treatment monitoring of colorectal cancer using individualized ctDNA validated by multi-regional molecular profiling

G. Mills, S. Nishizuka, Z. Ju, 2020, medRxiv.

Prognosis Tumor Epidermal Growth Factor Receptor and EGFRPY 1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

G. Mills, J. Siegfried, A. Egloff, 2012 .

Liposomal antisense oligonucleotides for cancer therapy.

D. Siwak, A. Tari, G. Lopez-Berestein, 2004, Methods in enzymology.

Running title: Functional proteomics of human breast tumors Title: A novel approach to the study of the functional proteome in breast cancer Running title: Functional proteomics of human breast tumors

K. Coombes, A. Børresen-Dale, W. Kuo, 2008 .

Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets

S. Nishizuka, Yiling Lu, Ju-Seog Lee, 2022, Nature Communications.

The HER2/Grb2/Akt pathway regulates the DNA binding activity of AP-1 in breast cancer cells.

D. Siwak, A. Tari, E. Mendoza-Gamboa, 2004, Oncology reports.

Curcumin‐induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IκB kinase and nuclear factor κB activity and are independent of the B‐Raf/mitogen‐activated/extracellular signal‐regulated protein kinase pathway and the Akt pathway

B. Aggarwal, R. Kurzrock, S. Shishodia, 2005, Cancer.

Suppression of Nuclear Factor-κB by Glucocorticoid Receptor Blocks Estrogen-Induced Apoptosis in Estrogen-Deprived Breast Cancer Cells

D. Siwak, V. Jordan, B. Abderrahman, 2019, Molecular Cancer Therapeutics.

The potential of drug-carrying immunoliposomes as anticancer agents. Commentary re: J. W. Park et al., Anti-HER2 immunoliposomes: enhanced efficacy due to targeted delivery. Clin. Cancer Res., 8: 1172-1181, 2002.

D. Siwak, A. Tari, G. Lopez-Berestein, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

G. Mills, J. Siegfried, A. Egloff, 2012, Clinical Cancer Research.

Telomere 3′ overhang‐specific DNA oligonucleotides induce autophagy in malignant glioma cells

G. Mills, K. Hess, M. Eller, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.

G. Mills, H. Allgayer, I. Asangani, 2009, Cancer research.

LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

G. Mills, Takla Griss, Russell G. Jones, 2013, Cancer & metabolism.

GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity

G. Mills, P. Siegel, D. Siwak, 2019, Oncogene.

Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19‐9 levels in pancreatic cancer

Gordon B Mills, Doris R Siwak, David C Whitcomb, 2008, Proteomics.

Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance.

G. Mills, P. Wipf, P. Dent, 2009, Cancer research.

Src activation regulates anoikis in human colon tumor cell lines

A. Kraker, D. McConkey, D. Siwak, 2002, Oncogene.

Development of a robust classifier for quality control of reverse-phase protein arrays

John N. Weinstein, Wenbin Liu, Kevin R. Coombes, 2015, Bioinform..

RPPA SPACE: an R package for normalization and quantitation of Reverse-Phase Protein Array data

James M. Melott, J. Weinstein, Z. Ju, 2022, Bioinform..

Frequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling

G. Mills, L. Liotta, S. Nishizuka, 2021, British Journal of Cancer.

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer

Jill M. Siegfried, Doris R. Siwak, Gordon B. Mills, 2007, Molecular Cancer Therapeutics.

Analytical Platforms 3: Processing Samples via the RPPA Pipeline to Generate Large-Scale Data for Clinical Studies.

Yiling Lu, Rehan Akbani, Jun Li, 2019, Advances in experimental medicine and biology.

Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

G. Mills, Z. Estrov, S. Kornblau, 2013, PloS one.

HER2/neu uses Akt to suppress retinoic acid response element binding activity in MDA-MB-453 breast cancer cells.

D. Siwak, A. Tari, E. Mendoza-Gamboa, 2003, International journal of oncology.

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition.

Laura M. Heiser, Nicholas J. Wang, P. Spellman, 2009, Cancer research.

Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.

G. Mills, H. Allgayer, I. Asangani, 2009, Cancer research.

Dynamic phospho-proteogenomic analysis of gastric cancer cells suggests host immunity provides survival benefit

D. Siwak, E. Petricoin, Y. Koizumi, 2024, medRxiv.

LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

G. Mills, Takla Griss, Russell G. Jones, 2013, Cancer & Metabolism.