B. Rocha

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CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

Henrique Veiga-Fernandes, A. Peixoto, C. Evaristo, 2007, The Journal of experimental medicine.

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

Jan Tavernier, Eric Vivier, Laurence Zitvogel, 2011, Nature Medicine.

Life span of B lymphocytes: the experimental basis for conflicting results.

A. Coutinho, B. Rocha, A. Freitas, 1986, Journal of immunology.

Response of naïve and memory CD8+ T cells to antigen stimulation in vivo

Henrique Veiga-Fernandes, B. Rocha, H. Veiga-Fernandes, 2000, Nature Immunology.

A Molecular Gut Reaction

B. Rocha, F. Lambolez, 2001, Science.

Towards a cellular definition of CD8+ T-cell memory: the role of CD4+ T-cell help in CD8+ T-cell responses.

B. Rocha, C. Tanchot, Corinne Tanchot, 2004, Current opinion in immunology.

γc deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors

J. D. Di Santo, I. Munitic, B. Rocha, 2010, Proceedings of the National Academy of Sciences.

Lymphocyte Migration into Collagen Gels: Role of Lymph

B. Rocha, A. Freitas, W. Haston, 1984, Scandinavian journal of immunology.

Lymphocytes migration into membrane filters: divergent effects of syngeneic mouse serum and lymph.

B. Rocha, A. Freitas, J. L. de Miranda, 1984, Annales d'immunologie.

Cell-to-Cell Interactions and Signals Involved in the Reconstitution of Peripheral CD8+ TCM and TEM Cell Pools

B. Malissen, C. Evaristo, B. Rocha, 2011, PloS one.

Lymphocyte Population Kinetics in the Mouse

A. Coutinho, B. Rocha, A. Freitas, 1986, Immunological reviews.

Commentary: Maintenance of CD8+ T Memory Lymphocytes in the Spleen but Not in the Bone Marrow Is Dependent on Proliferation

B. Rocha, F. Di Rosa, 2018, Front. Immunol..

Accumulation of bromodeoxyuridine‐labeled cells in central and peripheral lymphoid organs: minimal estimates of prodution and turnover rates of mature lymphocytes

B. Rocha, A. Freitas, C. Pénit, 1990, European journal of immunology.

Interleukin 2 receptor expression and interleukin 2 production in exponentially growing T cells: major differences between in vivo and in vitro proliferating T lymphocytes

B. Rocha, A. Freitas, M. Lembezat, 1989, European journal of immunology.

Effects of Hydroxyurea on Concanavalin‐A‐Induced T‐Cell Proliferation

B. Rocha, A. Freitas, E. Larsson, 1984, Scandinavian journal of immunology.

Two major classes of mitogen-reactive B lymphocytes defined by life span.

A. Coutinho, B. Rocha, A. Freitas, 1986, Journal of immunology.

Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice

B. Rocha, P. Vassalli, D. Guy‐grand, 1994, The Journal of experimental medicine.

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

A. Cumano, L. Rogge, B. Rocha, 2006, Nature Immunology.

CD8 lethargy in the absence of CD4 help

B. Rocha, H. Veiga-Fernandes, C. Bourgeois, 2002, European journal of immunology.

A unique CD8(+) T lymphocyte signature in pediatric type 1 diabetes.

P. van Endert, Y. Hamel, A. Hartemann, 2016, Journal of autoimmunity.

Cell-to-Cell Interactions and Signals Involved in the Reconstitution of Peripheral CD8 T(CM) and T(EM) Cell Pools

B. Malissen, C. Evaristo, B. Rocha, 2018 .

CD8 Memory Cells Develop Unique DNA Repair Mechanisms Favoring Productive Division

B. Rocha, J. de Villartay, F. Vasseur, 2015, PloS one.

The organization of mature T-cell pools.

B. Rocha, C. Tanchot, 2000, Immunology today.

Single Insulin-Speci fi c CD 8 + T Cells Show Characteristic Gene Expression Pro fi les in Human Type 1 Diabetes

F. Lemonnier, J. Coste, C. Boitard, 2011 .

Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut.

B. Rocha, H. von Boehmer, D. Guy‐grand, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Intra‐ and extra‐thymic expression of the pre‐T cell receptor α gene

A. Rolink, B. Rocha, H. Rodewald, 1995 .

Role of the gut as a primary lymphoid organ.

B. Rocha, L. Peaudecerf, Laetitia Peaudecerf, 2011, Immunology letters.

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation

B. Rocha, P. Vassalli, D. Guy‐grand, 1991, The Journal of experimental medicine.

Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation

B. Malissen, B. Rocha, P. Vassalli, 1994, The Journal of experimental medicine.

Selection of intraepithelial lymphocytes with CD8 a/a co-receptors by self-antigen in the murine gut

B. Rocha, D. Guy‐grand, H. Boehmert, 2022 .

The extrathymic T‐cell differentiation in the murine gut

B. Rocha, 2007, Immunological reviews.

Extrathymic T cell differentiation.

B. Rocha, P. Vassalli, D. Guy‐grand, 1995, Current opinion in immunology.

CD8 and B cell memory: same strategy, same signals

B. Rocha, C. Tanchot, Corinne Tanchot, 2003, Nature Immunology.

The Common Cytokine Receptor γ Chain and the Pre-T Cell Receptor Provide Independent but Critically Overlapping Signals in Early α/β T Cell Development

A. Fischer, H. Fehling, J. D. Di Santo, 1999, The Journal of experimental medicine.

The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs

M. Arcangeli, B. Rocha, C. Cordier, 2006, Nature Immunology.

Cartography of gene expression in CD8 single cells: novel CCR7- subsets suggest differentiation independent of CD45RA expression.

C. Evaristo, B. Rocha, A. Nicoletti, 2007, Blood.

T cell development in mice lacking the CD3‐zeta/eta gene.

E. Spanopoulou, B. Rocha, É. Vivier, 1993, EMBO Journal.

The extrathymic T-cell development pathway.

B. Rocha, P. Vassalli, D. Guy‐grand, 1992, Immunology today.

Requirements for memory maintenance

B. Rocha, 2002, Nature Immunology.

Cognate Antigen Stimulation Generates Potent CD8+ Inflammatory Effector T Cells

C. Evaristo, A. Charbit, B. Rocha, 2013, Front. Immunol..

An unusual lineage of alpha/beta T cells that contains autoreactive cells

B. Rocha, H. von Boehmer, H. Boehmer, 1991, The Journal of experimental medicine.

Molecular characterization of gut T cell precursors in euthymic and athymic mice.

B. Rocha, F. Lambolez, 2001, Advances in experimental medicine and biology.

Self–Nonself Discrimination by T Lymphocytes

B. Rocha, H. Boehmer, 1993 .

Single-Cell Analysis of Thymocyte Differentiation: Identification of Transcription Factor Interactions and a Major Stochastic Component in αβ-Lineage Commitment

B. Rocha, S. Candéias, A. Boudil, 2013, PloS one.

Thymocytes self‐renewal: a major hope or a major threat?

B. Rocha, L. Peaudecerf, F. Vasseur, 2016, Immunological Reviews.

Brief Definitive Report

J. D. Di Santo, B. Rocha, L. Peaudecerf, 2022 .

CD4/CD8/Dendritic cell complexes in the spleen: CD8+ T cells can directly bind CD4+ T cells and modulate their response

B. Rocha, F. Vasseur, A. Galgano, 2017, PloS one.

Extracellular Isoforms of CD6 Generated by Alternative Splicing Regulate Targeting of CD6 to the Immunological Synapse1

A. Peixoto, B. Rocha, G. Bismuth, 2007, The Journal of Immunology.

Characterization of Vβ‐bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation

B. Rocha, 1990 .

An Unusual Lineage of oL / / 3 T Cells that Contains Autoreactive Cells

B. Rocha, H. Boehmer, R. Kirberg, 2003 .

Generation of mature T cell populations in the thymus: CD4 or CD8 down‐regulation occurs at different stages of thymocyte differentiation

B. Rocha, G. Marodon, 1994, European journal of immunology.

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

A. Cumano, B. Rocha, S. Pellegrini, 2016, Biology Direct.

Homeostasis of naive T cells: the Foxo that fixes

B. Rocha, A. Freitas, 2009, Nature Immunology.

Erratum: A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

A. Cumano, L. Rogge, B. Rocha, 2006, Nature Immunology.

Activation and 'deletion' of self-reactive mature and immature T cells during ontogeny of Mls-1a mice: implications for neonatal tolerance induction.

B. Rocha, G. Marodon, 1994, International immunology.

The Vo Repertoire of Mouse Gut Homodimeric a CD 8 + Intraepithelial T Cell Receptor a / o + Lymphocytes Reveals a Major Extrathymic Pathway of T Cell Differentiation

B. Rocha, P. Vassalli, D. Guy‐grand, 2003 .

Differential requirements for survival and proliferation of CD8 naïve or memory T cells.

F. Lemonnier, B. Rocha, A. Freitas, 1997, Science.

Induction of tolerance in immature and mature T cells.

W. Swat, B. Rocha, H. von Boehmer, 1993, Transplantation proceedings.

Population biology of lymphocytes: the flight for survival.

B. Rocha, A. Freitas, B Rocha, 2000, Annual review of immunology.

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus

A. Fischer, D. Bonhomme, M. Cavazzana‐Calvo, 2007, The Journal of experimental medicine.

Peripheral T cell survival.

B. Rocha, A. Freitas, Benedita Rocha, 1999, Current opinion in immunology.

Divergent actions of monomeric, dimeric, and tetrameric concanavalin A on lymphocyte traffic.

B. Rocha, A. Freitas, J. Chiao, 1978, Cellular immunology.

A Role for CD40 Expression on CD8+ T Cells in the Generation of CD8+ T Cell Memory

B. Rocha, C. Bourgeois, C. Tanchot, 2002, Science.

High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division

B. Rocha, H. Veiga-Fernandes, 2004, Nature Immunology.

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

H. Volk, L. Chatenoud, B. Rocha, 2015, eLife.

Lymphocyte lifespans: homeostasis, selection and competition.

B. Rocha, A. Freitas, 1993, Immunology today.

Microbiota stimulation generates LCMV-specific memory CD8+ T cells in SPF mice and determines their TCR repertoire during LCMV infection.

J. D. Di Santo, B. Rocha, A. Lim, 2020, Molecular immunology.

Peripheral selection of the T cell repertoire.

B. Rocha, H. von Boehmer, H. Boehmer, 1991, Science.

Lymphocyte Survival: A Red Queen Hypothesis

B. Rocha, A. Freitas, 1997, Science.

Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes

F. Lemonnier, J. Coste, C. Boitard, 2011, Diabetes.

Population dynamics of B lymphocytes and their precursors: demonstration of high turnover in the central and peripheral lymphoid organs.

A. Coutinho, B. Rocha, A. Freitas, 1982, Journal of immunology.

Random recirculation of small T lymphocytes from thoracic duct lymph in the mouse.

B. Rocha, A. Freitas, M. Rose, 1980, Cellular immunology.

The Tower of Babel of CD8+ T‐cell memory: known facts, deserted roads, muddy waters, and possible dead ends

B. Rocha, C. Tanchot, Corinne Tanchot, 2006, Immunological reviews.

CD8 T cell memory.

B. Rocha, C. Tanchot, 2004, Seminars in immunology.

Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo

L. Tuosto, B. Rocha, O. Acuto, 2003, European journal of immunology.

Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen

B. Rocha, H. von Boehmer, H. Boehmer, 1993, The Journal of experimental medicine.

Selection of antibody repertoires: transfer of mature T lymphocytes modifies VH gene family usage in the actual and available B cell repertoires of athymic mice

B. Rocha, A. Freitas, M. Lembezat, 1989 .

Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8+CD11c+ PD-1lo Effector T Cells

B. Rocha, Nicolas Goudin, D. Gross, 2016, PloS one.

The effects of stress in normal and adrenalectomized mice

B. Rocha, 1985, European journal of immunology.

T cell deletion induced by chronic infection with mouse mammary tumor virus spares a CD25-positive, IL-10-producing T cell population with infectious capacity.

B. Rocha, C. Pénit, M. Dy, 1997, Journal of immunology.

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance

B. Rocha, A. Grandien, A. Freitas, 1995, The Journal of experimental medicine.

Transcriptional regulation during CD8 T-cell immune responses.

C. Evaristo, B. Rocha, H. Sung, 2010, Advances in experimental medicine and biology.

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

A. Cumano, B. Rocha, S. Pellegrini, 2016, Biology Direct.

Quantification of multiple gene expression in individual cells.

B. Rocha, H. Veiga-Fernandes, Marta Monteiro, 2004, Genome research.

Characterization of V beta-bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation.

B. Rocha, 1990, European journal of immunology.

Characterization of T Cell Differentiation in the Murine Gut

J. D. Di Santo, B. Rocha, H. von Boehmer, 2002, The Journal of experimental medicine.

Extrathymic Hemopoietic Progenitors Committed to T Cell Differentiation in the Adult Mouse1

M. Arcangeli, B. Rocha, E. Schneider, 2005, The Journal of Immunology.

Major T Cell Progenitor Activity in Bone Marrow–derived Spleen Colonies

M. Arcangeli, B. Rocha, E. Schneider, 2002, The Journal of experimental medicine.

CD6 to the Immunological Synapse Alternative Splicing Regulate Targeting of Extracellular Isoforms of CD6 Generated by

B. Rocha, G. Bismuth, A. Brown, 2017 .

The organization of mature T-cell pools.

B. Rocha, H. V. Fernandes, C. Tanchot, 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Induction of Immunological Unresponsiveness in vivo and in vitro by Conventional and Super‐Antigens in Developing and Mature T Cells

W. Swat, B. Rocha, P. Kisielow, 1991, Immunological reviews.

Epitope Specificity and Relative Clonal Abundance Do Not Affect CD8 Differentiation Patterns during Lymphocytic Choriomeningitis Virus Infection

P. Borrow, J. D. Di Santo, C. Evaristo, 2009, Journal of Virology.

Modifications of CD8+ T cell function during in vivo memory or tolerance induction.

A. Trautmann, B. Rocha, J. Delon, 1998, Immunity.

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

B. Rocha, Pablo Pereira, Benedita Rocha, 1989, European journal of immunology.

Lymphocyte homeostasis.

B. Rocha, F. Agenès, M. Rosado, 1997, Seminars in immunology.

Peripheral Selection of T Cell Repertoires: The Role of Continuous Thymus Output

B. Rocha, C. Tanchot, Corinne Tanchot, 1997, The Journal of experimental medicine.

A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL‐10 secretion and T cell homeostasis

B. Rocha, C. Cordier, M. Papiernik, 2003, European journal of immunology.

Population dynamics of T lymphocytes. Renewal rate and expansion in the peripheral lymphoid organs.

A. Coutinho, B. Rocha, A. Freitas, 1983, Journal of immunology.

Limiting Dilution Analysis of Interleukin 2‐Producing Mature T Cells

B. Rocha, A. Bandeira, Antonio Bandeira, 1988, Scandinavian journal of immunology.

NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients

J. Blay, N. Halama, J. Koch, 2017, Oncoimmunology.

A new mechanism shapes the naïve CD8+ T cell repertoire: the selection for full diversity

G. Lythe, B. Rocha, F. Vasseur, 2017, Molecular Immunology.

The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools

B. Rocha, C. Tanchot, Corinne Tanchot, 1995, European journal of immunology.

Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells.

B. Rocha, A. Freitas, Afonso R M Almeida, 2005, Seminars in immunology.

Tissue distribution of Mtv-7-like exogenous retroviral transcripts and clonal deletion of V beta 6+ T cells in Mls-1b BALB/c mice.

A. Korman, B. Rocha, M. Papiernik, 1993, International immunology.

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

I. Williams, G. Shaw, P. Borrow, 2012, Blood.

IL-2-dependent proliferation of thymic accessory cells.

B. Rocha, A. Lehuen, M. Papiernik, 1988, Journal of immunology.

Population kinetics of precursors of IL 2-producing peripheral T lymphocytes: evidence for short life expectancy, continuous renewal, and post-thymic expansion.

B. Rocha, 1987, Journal of immunology.

Spleen lymphocyte populations in patients with Hodgkin's disease--properties of cells with different densities.

B. Rocha, A. Freitas, G. Munn, 1982, Clinical and experimental immunology.

Comment on "Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt+ Cells"

B. Rocha, 2005, Science.

The Common Cytokine Receptor γ Chain and the Pre-T Cell Receptor Provide Independent but Critically Overlapping Signals in Early α/β T Cell Development

A. Fischer, H. Fehling, J. D. Di Santo, 1999, The Journal of experimental medicine.

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance

B. Rocha, A. Grandien, A. Freitas, 1995, The Journal of experimental medicine.

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

I. Williams, G. Shaw, P. Borrow, 2012, Blood.

Peripheral Selection of T Cell Repertoires: The Role of Continuous Thymus Output

B. Rocha, Corinne Tanchot, 1997, The Journal of experimental medicine.

Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen

B. Rocha, H. Boehmer, Corinne Tanchot, 1993, The Journal of experimental medicine.

NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients

J. Blay, N. Halama, J. Koch, 2017, Oncoimmunology.

T cell subsets in patients with rheumatoid arthritis: reduction of cells with Leu 2A phenotype in patients with serum IgG immunocomplexes.

B. Rocha, M. Queirós, 1983, Clinical and experimental immunology.

An unusual lineage of alpha/beta T cells that contains autoreactive cells

B. Rocha, H. Boehmer, R. Kirberg, 1991, The Journal of experimental medicine.

In the absence of nominal antigen, survival of naïve cells and maintenance of CD8 T cell memory require TcR-MHC class I interactions

F. Lemonnier, B. Rocha, A. Freitas, 1997 .

CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

C. Evaristo, A. Charbit, B. Rocha, 2007, The Journal of experimental medicine.

Role of TCR‐restricting MHC density and thymic environment on selection and survival of cells expressing low‐affinity T cell receptors

R. Zinkernagel, B. Rocha, H. Hengartner, 2004, European journal of immunology.

Intra- and extra-thymic expression of the pre-T cell receptor alpha gene.

A. Rolink, B. Rocha, H. Rodewald, 1995, European Journal of Immunology.