M. Linton

发表

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

M. Linton, J. Moslehi, V. Babaev, 2019, International journal of molecular sciences.

Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis.

M. Linton, V. Babaev, Jiansheng Huang, 2016, Circulation journal : official journal of the Japanese Circulation Society.

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records

N. Cox, D. Roden, J. Denny, 2018, PLoS medicine.

Atherosclerosis in chronic kidney disease: the role of macrophages

M. Linton, V. Kon, S. Fazio, 2011, Nature Reviews Nephrology.

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

P. Sethupathy, Y. Shyr, K. Vickers, 2018, bioRxiv.

Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice

J. Morrow, S. Gautam, L. Marnett, 2002, Circulation.

Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice.

J. Morrow, J. Oates, M. Linton, 2005, Journal of molecular and cellular cardiology.

Genetic risk for major depressive disorder and loneliness in gender-specific associations with coronary artery disease

N. Cox, D. Ruderfer, D. Boomsma, 2019, bioRxiv.

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo.

M. Linton, V. Babaev, L. Gleaves, 1999, The Journal of clinical investigation.

Macrophage Lipoprotein Lipase Promotes Foam Cell Formation and Atherosclerosis in Low Density Lipoprotein Receptor-deficient Mice*

Mayur B. Patel, M. Linton, V. Babaev, 2000, The Journal of Biological Chemistry.

Reduced ABCA 1-Mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E – Deficient Mice Lacking Macrophage-Derived ACAT 1

M. Linton, S. Fazio, Y. Su, 2005 .

Reduced ABCA1-Mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E–Deficient Mice Lacking Macrophage-Derived ACAT1

M. Linton, S. Fazio, Y. Su, 2005, Circulation.

Isoform-Specific Effects of Apolipoprotein E on Atherogenesis: Gene Transduction Studies in Mice

M. Linton, V. Babaev, L. Gleaves, 2001, Circulation.

Lifestyle determinants of C-reactive protein in middle-aged, urban Chinese men.

H. Cai, Y. Xiang, T. Elasy, 2012, Nutrition, metabolism, and cardiovascular diseases : NMCD.

IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD.

A. Hung, T. Ikizler, M. Chonchol, 2019, Clinical journal of the American Society of Nephrology : CJASN.

Physiological relevance of apolipoprotein E recycling: studies in primary mouse hepatocytes.

M. Linton, S. Fazio, A. Hasty, 2005, Metabolism: clinical and experimental.

Intra-individual Variation of Plasma Adipokine Levels and Utility of Single Measurement of These Biomarkers in Population-Based Studies

X. Shu, Y. Xiang, W. Zheng, 2007, Cancer Epidemiology Biomarkers & Prevention.

Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis.

K. Vickers, M. Linton, H. Tao, 2021, The Journal of clinical investigation.

A Recycling Pathway for Resecretion of Internalized Apolipoprotein E in Liver Cells*

M. Linton, S. Fazio, A. Major, 2001, The Journal of Biological Chemistry.

The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes

M. Linton, S. Fazio, A. Hasty, 2003, The Journal of Biological Chemistry.

Recycling of Apolipoprotein E in Mouse Liver*

M. Linton, S. Fazio, A. Hasty, 1999, The Journal of Biological Chemistry.

Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation.

M. Linton, V. Babaev, L. Gleaves, 1999, Circulation.

Lack of macrophage fatty-acid–binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

Jeffrey B. Boord, R. Parker, J. Suttles, 2001, Nature Medicine.

Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).

Robert V Farese, R. Hammer, H. Hobbs, 1993, The Journal of clinical investigation.

Re-emergence of fibrates in the management of dyslipidemia and cardiovascular risk

M. Linton, S. Fazio, 2000, Current atherosclerosis reports.

Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice

M. Linton, V. Babaev, G. Hotamisligil, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Macrophages, inflammation, and atherosclerosis

M. Linton, S. Fazio, 2003, International Journal of Obesity.

Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs

M. Linton, B. Li, S. Fazio, 2017, PloS one.

Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

D. Ledbetter, J. Knowles, D. Rader, 2018, Journal of the American College of Cardiology.

Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-&ggr;–Regulated Genes

M. Linton, V. Babaev, H. Tao, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Macrophage IKK&agr; Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis

M. Linton, V. Babaev, L. Ding, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A

T. Kodama, M. Linton, V. Babaev, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Inactivation of Macrophage Scavenger Receptor Class B Type I Promotes Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice

M. Linton, V. Babaev, P. Yancey, 2003, Circulation.

Macrophage Apolipoprotein E Reduces Atherosclerosis and Prevents Premature Death in Apolipoprotein E and Scavenger Receptor–Class BI Double-Knockout Mice

M. Koury, M. Linton, P. Yancey, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Severely altered cholesterol homeostasis in macrophages lacking apoE and SR-BI Published, JLR Papers in Press, February 13, 2007.

M. Linton, V. Babaev, P. Yancey, 2007, Journal of Lipid Research.

Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity

M. Linton, Jiansheng Huang, H. Tao, 2020, Nutrients.

Adipocyte Fatty Acid–Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation in Severe Hypercholesterolemia

Jeffrey B. Boord, M. Linton, V. Babaev, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

P. Sethupathy, Y. Shyr, K. Vickers, 2018, bioRxiv.

Overexpression of Human Apolipoprotein A-I Preserves Cognitive Function and Attenuates Neuroinflammation and Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer Disease*

M. Linton, L. Jungbauer, M. LaDu, 2010, The Journal of Biological Chemistry.

Dysfunctional high-density lipoprotein in patients on chronic hemodialysis.

T. Ikizler, M. Linton, P. Yancey, 2012, Journal of the American College of Cardiology.

Are statins diabetogenic?

U. Sampson, M. Linton, S. Fazio, 2011, Current opinion in cardiology.

Fenofibrate and risk of minor amputations in diabetes

M. Linton, S. Fazio, 2009, The Lancet.

Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice.

M. Linton, P. Yancey, A. Fogo, 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

HDL: Beyond Atheroprotection.

M. Linton, V. Kon, 2016, Journal of the American Society of Nephrology : JASN.

Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor.

M. Linton, V. Babaev, S. Fazio, 1998, The Journal of clinical investigation.

Apolipoprotein E and Reverse Cholesterol Transport: The Role of Recycling in Plasma and Intracellular Lipid Trafficking

M. Linton, S. Fazio, A. Hasty, 2007 .

Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese men.

X. Shu, Yu-tang Gao, Y. Xiang, 2009, Metabolic syndrome and related disorders.

Macrophage Expression of Peroxisome Proliferator–Activated Receptor-&agr; Reduces Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

M. Linton, V. Babaev, P. Yancey, 2007, Circulation.

Inflammatory mechanisms affecting the lipid profile in patients with systemic lupus erythematosus.

M. Linton, T. Gebretsadik, C. Stein, 2007, The Journal of rheumatology.

A case of severe acquired hypertriglyceridemia in a 7-year-old girl.

M. Linton, S. Fazio, H. Tavori, 2017, Journal of clinical lipidology.

Renal Dysfunction Potentiates Foam Cell Formation by Repressing ABCA1

M. Linton, P. Yancey, A. Fogo, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.

I. Narita, M. Linton, P. Yancey, 2015, Atherosclerosis.

Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.

M. Linton, V. Babaev, A. Fogo, 2007, Journal of the American Society of Nephrology : JASN.

Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.

M. Linton, V. Babaev, A. Fogo, 2006, Atherosclerosis.

Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.

M. Linton, V. Babaev, A. Fogo, 2006, Journal of the American Society of Nephrology : JASN.

Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.

M. Linton, T. Matsusaka, A. Fogo, 2002, The Journal of clinical investigation.

High‐Density Lipoprotein Cholesterol Concentration and Acute Kidney Injury After Cardiac Surgery

M. Linton, J. Blume, F. Billings, 2017, Journal of the American Heart Association.

A new age of discovery for plasma lipoproteins.

M. Linton, S. Fazio, 2007, Current opinion in lipidology.

Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500101-JLR200

M. Linton, A. Rusiñol, S. Fazio, 2005, Journal of Lipid Research.

Acyl-CoA : Cholesterol Acyltransferase Promotes Oxidized LDL / Oxysterol-Induced Apoptosis in Macrophages

M. Linton, S. Fazio, D. Hachey, 2005 .

ACAT inhibition: bad for macrophages, good for smooth muscle cells?

M. Linton, S. Fazio, D. Dove, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE FH Registry.

Emily C. O'Brien, J. Knowles, S. Gidding, 2020, The Journal of pediatrics.

A Pathway-Dependent on ApoE, ApoAI, and ABCA1 Determines Formation of Buoyant High-Density Lipoprotein by Macrophage Foam Cells

M. Linton, P. Yancey, S. Fazio, 2007, Arteriosclerosis, thrombosis, and vascular biology.

The relationship between dose of vitamin E and suppression of oxidative stress in humans.

J. Morrow, J. Oates, Y. Shyr, 2007, Free radical biology & medicine.

Cyclooxygenase-2 and atherosclerosis

M. Linton, S. Fazio, 2002, Current opinion in lipidology.

Cyclooxygenase-2 and inflammation in atherosclerosis.

M. Linton, S. Fazio, 2004, Current opinion in pharmacology.

Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.

J. Savage, M. Linton, P. Yancey, 2015, Antioxidants & redox signaling.

Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-&agr; Inhibition

M. Linton, L. Ding, S. Fazio, 2016, Arteriosclerosis, thrombosis, and vascular biology.

US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry.

Emily C. O'Brien, J. Knowles, D. Rader, 2016, Journal of clinical lipidology.

Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr−/− mice

O. Boutaud, J. Oates, M. Linton, 2019, Nature Communications.

byinhibitingfatty-acid-bindingproteinaP2

R. Parker, G. Atsumi, M. Linton, 2007 .

Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis

Jeffrey B. Boord, M. Linton, S. Fazio, 2002, Current opinion in lipidology.

Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages.

Robert V Farese, M. Linton, L. Gleaves, 2001, The Journal of clinical investigation.

Leukocyte low density lipoprotein receptor (LDL-R) does not contribute to LDL clearance in vivo: bone marrow transplantation studies in the mouse.

M. Linton, S. Fazio, J. Price, 1997, Journal of lipid research.

Macrophage Polarization by Angiotensin II-Type 1 Receptor Aggravates Renal Injury-Acceleration of Atherosclerosis

M. Linton, P. Yancey, Li-jun Ma, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Liver enzymes, type 2 diabetes, and metabolic syndrome in middle-aged, urban Chinese men.

X. Shu, Y. Xiang, W. Zheng, 2011, Metabolic syndrome and related disorders.

CHAPTER 2 – Regulation and Clearance of Apolipoprotein B–Containing Lipoproteins

M. Linton, S. Fazio, 2009 .

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.

D. Rader, J. Witztum, M. Linton, 1999, The Journal of clinical investigation.

Purine-rich foods, protein intake, and the prevalence of hyperuricemia: the Shanghai Men's Health Study.

X. Shu, W. Zheng, H. Cai, 2012, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.

Deanna L. Plubell, Rachel M. Devay, I. Predazzi, 2016, Cardiovascular research.

Local effects of human PCSK9 on the atherosclerotic lesion

Rachel M. Devay, I. Predazzi, M. Linton, 2016, The Journal of pathology.

Serum Proprotein Convertase Subtilisin/Kexin Type 9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation

M. Linton, P. Yancey, L. Ding, 2013, Circulation.

Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor–Dependent and –Independent Mechanisms

M. Linton, S. Fazio, S. Rashid, 2014, Circulation.

Response to letter regarding article, "Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms".

M. Linton, S. Fazio, S. Rashid, 2015, Circulation.

Serum PCSK9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation

M. Linton, P. Yancey, L. Ding, 2013 .

Conditional Knockout of Macrophage PPARγ Increases Atherosclerosis in C57BL/6 and Low-Density Lipoprotein Receptor–Deficient Mice

M. Linton, V. Babaev, P. Yancey, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Combined Vitamin C and Vitamin E Deficiency Worsens Early Atherosclerosis in Apolipoprotein E–Deficient Mice

M. Linton, V. Babaev, Liying Li, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice

S. Ramsey, K. Vickers, M. Linton, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Macrophage apolipoprotein A-I expression protects against atherosclerosis in ApoE-deficient mice and up-regulates ABC transporters.

M. Linton, V. Babaev, S. Fazio, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500181-JLR200

M. Linton, S. Fazio, A. Hasty, 2005, Journal of Lipid Research.

Retrovirus-mediated Expression of Apolipoprotein A-I in the Macrophage Protects against Atherosclerosis in Vivo *

M. Linton, V. Babaev, S. Fazio, 2001, The Journal of Biological Chemistry.

Increased Cholesterol Efflux in Apolipoprotein AI (ApoAI)–Producing Macrophages as a Mechanism for Reduced Atherosclerosis in ApoAI(−/−) Mice

M. Linton, S. Fazio, Y. Su, 2001, Arteriosclerosis, thrombosis, and vascular biology.

Dysfunctional high-density lipoproteins in children with chronic kidney disease.

K. Vickers, M. Linton, P. Yancey, 2015, Metabolism: clinical and experimental.

Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells Published, JLR Papers in Press, March 13, 2006.

K. Weisgraber, M. Linton, P. Yancey, 2006, Journal of Lipid Research.

Expression of carboxyl-terminally truncated forms of human apolipoprotein B in rat hepatoma cells. Evidence that the length of apolipoprotein B has a major effect on the buoyant density of the secreted lipoproteins.

S. Young, M. Linton, B. Mccarthy, 1991, The Journal of biological chemistry.

SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis

M. Linton, E. Linton, H. Tao, 2017, Trends in Endocrinology & Metabolism.

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis[S]

M. Linton, V. Babaev, H. Tao, 2015, Journal of Lipid Research.

Sorting out the complexities of reverse cholesterol transport: CETP polymorphisms, HDL, and coronary disease.

M. Linton, S. Fazio, 2006, The Journal of clinical endocrinology and metabolism.

Interplay between apolipoprotein E and scavenger receptor class B type I controls coronary atherosclerosis and lifespan in the mouse.

M. Linton, S. Fazio, 2005, Circulation.

Unique pathway for cholesterol uptake in fat cells.

M. Linton, S. Fazio, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

C. Kahn, J. Suttles, T. Kadowaki, 2006, Cell metabolism.

Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice

M. Linton, V. Babaev, Jiansheng Huang, 2018, Front. Immunol..

Imaging mass spectrometry reveals heterogeneity of proliferation and metabolism in atherosclerosis.

M. Linton, V. Babaev, M. Steinhauser, 2019, JCI insight.

Rapid quantification of murine ABC mRNAs by real time reverse transcriptase-polymerase chain reaction Published, JLR Papers in Press, September 1, 2002. DOI 10.1194/jlr.D200020-JLR200

M. Linton, S. Fazio, Y. Su, 2002, Journal of Lipid Research.

Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice DOI 10.1194/jlr.M200108-JLR200

M. Linton, V. Babaev, S. Fazio, 2002, Journal of Lipid Research.

Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol: a case for resistin.

M. Linton, S. Fazio, 2012, Journal of the American College of Cardiology.

PCSK9, a novel target for lowering LDL cholesterol: promise and progress

M. Linton, S. Fazio, H. Tavori, 2012 .

The cell biology and physiologic relevance of ApoE recycling.

M. Linton, S. Fazio, L. Swift, 2000, Trends in cardiovascular medicine.

When it looks like familial hypercholesterolemia...but is not.

M. Linton, S. Fazio, 2012, Circulation. Cardiovascular genetics.

Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages

M. Linton, S. Fazio, J. Stafford, 2018, Circulation.

Hepatocyte-derived ApoE Is More Effective than Non-hepatocyte-derived ApoE in Remnant Lipoprotein Clearance*

K. Weisgraber, M. Linton, D. Sanan, 2003, The Journal of Biological Chemistry.

Apolipoprotein B gene mutations affecting cholesterol levels

Robert V Farese, S. Young, M. Linton, 1992, Journal of internal medicine.

Lp(a) in Childhood

M. Linton, E. Linton, J. Kelley, 2017, Current Cardiovascular Risk Reports.

Genetic abnormalities in apolipoprotein B.

S. Young, M. Linton, S. Young, 1991, Trends in cardiovascular medicine.

Angiotensin receptor blocker vs ACE inhibitor effects on HDL functionality in patients on maintenance hemodialysis.

T. Ikizler, M. Linton, N. Brown, 2018, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Inhibition of apolipoprotein(a) synthesis by farnesoid X receptor and fibroblast growth factor 15/19: a step toward selective lipoprotein(a) therapeutics.

M. Linton, S. Fazio, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

Robert V Farese, S. J. Smith, M. Linton, 2000, The Journal of clinical investigation.

Cyclooxygenase-1 Deficiency in Bone Marrow Cells Increases Early Atherosclerosis in Apolipoprotein E– and Low-Density Lipoprotein Receptor–Null Mice

J. Morrow, S. Dey, M. Linton, 2005, Circulation.

Dyslipidemias in children.

M. Linton, S. Fazio, Jessica Lilley, 2012, Pediatric annals.

Expression of P1 DNA in mammalian cells and transgenic mice.

S. Young, M. Linton, S. Mccormick, 1994, Genetic analysis, techniques and applications.

Targeting Epsins to Inhibit FGF Signaling while Potentiating TGF-β Signaling Constrains Endothelial-to-Mesenchymal-Transition in Atherosclerosis

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, bioRxiv.

Low levels of high-density lipoprotein cholesterol due to lecithin:cholesterol acyltransferase mutations increase carotid atherosclerosis.

M. Linton, S. Fazio, 2011, Journal of the American College of Cardiology.

Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry.

Emily C. O'Brien, J. Knowles, D. Rader, 2019, Atherosclerosis.

Loss of Plasma Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) After Lipoprotein Apheresis

M. Linton, S. Fazio, H. Tavori, 2013, Circulation research.

Perioperative high density lipoproteins, oxidative stress, and kidney injury after cardiac surgery

A. Remaley, M. Linton, P. Yancey, 2021, Journal of lipid research.

Low-Density Lipoprotein Receptor–Related Protein 1 Prevents Early Atherosclerosis by Limiting Lesional Apoptosis and Inflammatory Ly-6Chigh Monocytosis: Evidence That the Effects Are Not Apolipoprotein E Dependent

M. Linton, P. Yancey, L. Ding, 2011, Circulation.

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis (DOI:10.1016/j.cmet.2006.02.010)

C. Kahn, J. Suttles, T. Kadowaki, 2006 .

LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8

C. Duvall, K. Vickers, M. Linton, 2021, Nature Cell Biology.

Expression of Scavenger Receptor-A Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific

T. Kodama, Hiroshi Suzuki, M. Linton, 2000 .

ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages.

M. Linton, S. Fazio, Y. Su, 2006, Atherosclerosis.

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL[S]

S. Young, M. Sleeman, M. Linton, 2016, Journal of Lipid Research.

Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice.

Mayur B. Patel, J. Morrow, L. Marnett, 2005, Biochemical pharmacology.

PCSK9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein-B Lipoproteins Through Both LDL-Receptor Dependent and Independent Mechanisms Running title: Rashid et al.; PCSK9 Promotes Intestinal ApoB Overproduction

M. Linton, S. Fazio, S. Rashid, 2014 .

Identification and characterization of truncated forms of apolipoprotein B in hypobetalipoproteinemia.

Robert V Farese, S. Young, E. Krul, 1996, Methods in enzymology.

Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation

M. Linton, P. Yancey, L. Ding, 2010, Arteriosclerosis, thrombosis, and vascular biology.

ACAT1 Deficiency Disrupts Cholesterol Efflux and Alters Cellular Morphology in Macrophages

M. Linton, S. Fazio, Y. Su, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Targeting Epsins to Inhibit FGF Signaling while Potentiating TGF-β Signaling Constrains Endothelial-to-Mesenchymal-Transition in Atherosclerosis

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, bioRxiv.

Targeting Epsins by nanotherapy regulates lipid metabolism and promotes ABCG1-mediated cholesterol efflux to fortify atheroma regression

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, bioRxiv.

Scavenging dicarbonyls with 5’-O-pentyl-pyridoxamine improves insulin sensitivity and reduces atherosclerosis through modulating inflammatory Ly6Chi monocytosis and macrophage polarization

J. Oates, M. Linton, Jiansheng Huang, 2019 .

Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Preserves HDL Atheroprotective Functions

M. Linton, Jiansheng Huang, H. Tao, 2019, bioRxiv.

Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice.

F. Baralle, M. Linton, V. Babaev, 2008, Atherosclerosis.

PCSK 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein-B Lipoproteins Through Both LDL-Receptor Dependent and Independent Mechanisms Running title :

M. Linton, S. Fazio, S. Rashid, 2014 .

The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment: evidence for multiple redundant pathways.

K. Weisgraber, M. Linton, V. Shepherd, 2004, Journal of lipid research.

Determination of the lower threshold of apolipoprotein E resulting in remnant lipoprotein clearance.

M. Linton, S. Fazio, A. Hasty, 1999, Journal of lipid research.

Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia

M. Linton, P. Yancey, V. Amarnath, 2019, The Journal of Biological Chemistry.

4-oxo-2-nonenal Adducts In HDL Are Elevated In Familial Hypercholesterolemia: Identification Of Modified Sites And Functional Consequences

M. Linton, P. Yancey, W. Davidson, 2019, bioRxiv.

The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I.

K. Weisgraber, M. Linton, S. Fazio, 2005, Journal of lipid research.

Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury

Elaine L. Shelton, M. Linton, T. Matsusaka, 2022, JCI insight.

Quantitative and Qualitative Differences in Proatherogenic NKT Cells in Apolipoprotein E–Deficient Mice

Michael T. Wilson, M. Linton, S. Fazio, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Current perspectives on statins.

M. Linton, D. Maron, S. Fazio, 2000, Circulation.

Scavenging dicarbonyls with 5′-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance

M. Linton, Jiansheng Huang, H. Tao, 2022, bioRxiv.

Lipoprotein Modulation of Proteinuric Renal Injury

I. Pastan, T. Ikizler, M. Linton, 2019, Laboratory Investigation.

Association of soy food intake with risk and biomarkers of coronary heart disease in Chinese men.

X. Shu, Y. Xiang, W. Zheng, 2014, International journal of cardiology.

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia

S. Young, C. Pullinger, D. Blom, 2017, The New England journal of medicine.

B-Lymphocyte Deficiency Increases Atherosclerosis in LDL Receptor–Null Mice

M. Linton, S. Fazio, A. Major, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Falsely Decreased Carbon Dioxide in Patients with Hypertriglyceridemia.

A. Woodworth, M. Linton, G. Sephel, 2017, The journal of applied laboratory medicine.

Failure of ACAT inhibition to retard atherosclerosis.

M. Linton, S. Fazio, 2006, The New England journal of medicine.

Reading-frame Restoration by Transcriptional Slippage at Long Stretches of Adenine Residues in Mammalian Cells*

S. Young, M. Linton, M. Raabe, 1997, The Journal of Biological Chemistry.

Quantitative Estimates of the Variability of In Vivo Sonographic Measurements of the Mouse Aorta for Studies of Abdominal Aortic Aneurysms and Related Arterial Diseases

J. Gore, F. Harrell, U. Sampson, 2011, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

A practical approach to risk assessment to prevent coronary artery disease and its complications.

M. Linton, S. Fazio, 2003, The American journal of cardiology.

Features of the most commonly used mouse models of dyslipidemia and atherosclerosis

M. Linton, S. Fazio, 2002 .

Mouse models of hyperlipidemia and atherosclerosis.

M. Linton, S. Fazio, 2001, Frontiers in bioscience : a journal and virtual library.

Progressively decreasing plasma high-density lipoprotein cholesterol levels preceding diagnosis of smoldering myeloma.

M. Linton, S. Fazio, Linda S. May-Zhang, 2020, Journal of clinical lipidology.

The role of fibrates in managing hyperlipidemia: Mechanisms of action and clinical efficacy

M. Linton, S. Fazio, 2004, Current atherosclerosis reports.

A Direct Role for the Macrophage Low Density Lipoprotein Receptor in Atherosclerotic Lesion Formation*

M. Linton, V. Babaev, L. Gleaves, 1999, The Journal of Biological Chemistry.

Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice

K. Vickers, M. Linton, V. Babaev, 2014, Journal of Lipid Research.

Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats.

C. Marcantoni, M. Linton, Li-jun Ma, 2001, Kidney international.

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

S. Young, W. Bry, M. Linton, 1991, The Journal of clinical investigation.

Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry.

Emily C. O'Brien, J. Knowles, D. Rader, 2017, Atherosclerosis.

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry

Emily C. O'Brien, J. Knowles, D. Rader, 2016, Circulation. Cardiovascular genetics.

Retention of Low-Density Lipoprotein in Atherosclerotic Lesions of the Mouse: Evidence for a Role of Lipoprotein Lipase

J. Borén, M. Linton, S. Olofsson, 2007, Circulation research.

JCL roundtable: Lipids and inflammation in atherosclerosis.

E. Fisher, K. Bornfeldt, M. Linton, 2021, Journal of clinical lipidology.

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

R. Parker, G. Atsumi, M. Linton, 2007, Nature.

Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression

D. Head, M. Linton, J. Laborda, 2002, Journal of cellular biochemistry.

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

S. Watkins, M. Wiest, M. Linton, 2009, Nature Medicine.

Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation

Hao Wu, K. Ley, O. Kocher, 2019, Circulation research.

Quantum dot mediated imaging of atherosclerosis

M. Linton, F. Haselton, S. Fazio, 2009, Nanotechnology.

Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion

K. Vickers, M. Linton, Shilin Zhao, 2019, Scientific Reports.

Lentiviral Transduction of ApoAI Into Hematopoietic Progenitor Cells and Macrophages: Applications to Cell Therapy of Atherosclerosis

M. Linton, S. Fazio, Y. Su, 2008, Arteriosclerosis, thrombosis, and vascular biology.

A Mendelian Randomization Approach Using 3-HMG-Coenzyme-A Reductase Gene Variation to Evaluate the Association of Statin-Induced Low-Density Lipoprotein Cholesterol Lowering With Noncardiovascular Disease Phenotypes

H. Hakonarson, M. Lee, J. Denny, 2021, JAMA network open.

The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach

Wei-Qi Wei, C. Shaffer, Q. Feng, 2023, Clinical and translational science.

Proatherogenic role for NK cells revealed.

M. Linton, S. Fazio, A. Major, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

Robert V Farese, S. Young, M. Linton, 1995, The Journal of clinical investigation.

Angiotensin II Amplifies Macrophage-Driven Atherosclerosis

M. Linton, V. Babaev, A. Fogo, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Deletion of Macrophage LDL Receptor–Related Protein Increases Atherogenesis in the Mouse

M. Linton, P. Yancey, S. Fazio, 2007, Circulation research.

Multisystem Progeroid Syndrome With Lipodystrophy, Cardiomyopathy, and Nephropathy Due to an LMNA p.R349W Variant

R. Hegele, A. Garg, M. Linton, 2020, Journal of the Endocrine Society.

Killing two birds with one stone, maybe: CETP inhibition increases both high-density lipoprotein levels and insulin secretion.

M. Linton, S. Fazio, 2013, Circulation research.

Genetic Disorders of HDL Metabolism

M. Linton, S. Fazio, Jessica Lilley, 2015 .

Regulation of Tumor Necrosis Factor Receptor-1 and the Ikk-nf-␬b Pathway by Ldl Receptor–related Protein Explains the Antiinflammatory Activity of This Receptor Low-density Lipoprotein Receptor–related Protein (lrp-1) Functions in Endocytosis and in Cell Signaling Directly (by Binding Signaling Adap

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2022 .

Contemporary patterns of lipoprotein(a) testing and associated clinical care and outcomes.

Emily C. O'Brien, Neha J. Pagidipati, P. Joshi, 2023, American journal of preventive cardiology.

Reduced Macrophage Apoptosis Is Associated With Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice

M. Linton, S. Fazio, Y. Su, 2004, Arteriosclerosis, thrombosis, and vascular biology.

The inflamed plaque: cytokine production and cellular cholesterol balance in the vessel wall.

M. Linton, S. Fazio, 2001, The American journal of cardiology.

Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease

D. Ruderfer, D. Boomsma, A. Palmer, 2019, Molecular Psychiatry.

Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis.

K. Vickers, M. Linton, Q. Sheng, 2019, Atherosclerosis.

Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, Circulation research.

Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges

U. Sampson, M. Linton, S. Fazio, 2012, Current Atherosclerosis Reports.

Combined Adipocyte-Macrophage Fatty Acid–Binding Protein Deficiency Improves Metabolism, Atherosclerosis, and Survival in Apolipoprotein E–Deficient Mice

Jeffrey B. Boord, M. Linton, V. Babaev, 2004, Circulation.

The Role of Lipids and Lipoproteins in Atherosclerosis

K. Vickers, M. Linton, E. Linton, 2015 .

Expression of human apolipoprotein B90 in transgenic mice. Demonstration that apolipoprotein B90 lacks the structural requirements to form lipoprotein.

H. Hobbs, S. Young, M. Linton, 1994, The Journal of biological chemistry.

Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis.

J. Oates, M. Linton, V. Babaev, 2008, Cell metabolism.

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function

M. Linton, Jiansheng Huang, P. Yancey, 2018, The Journal of Biological Chemistry.

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters HDL structure and function

M. Linton, Jiansheng Huang, P. Yancey, 2018 .

Evaluation of macrophage-specific promoters using lentiviral delivery in mice

J. Borén, D. Greaves, M. Linton, 2011, Gene Therapy.

activity of this receptor pathway by LDL receptor-related protein explains the antiinflammatory Regulation of tumor necrosis factor receptor-1 and the IKK-NF-{kappa}B

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2009 .

activity of this receptor related protein explains the antiinflammatory − pathway by LDL receptor B κ Regulation of tumor necrosis factor receptor-1 and the IKK

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2008 .

Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor−/− Mice Improves Indices of Cardiometabolic Disease

K. Boyd, M. Linton, P. Yancey, 2019, Scientific Reports.

Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies.

M. Linton, S. Fazio, Sergio Fazio, 1999, Current opinion in lipidology.

Prevalence and determinants of hyperuricemia in middle-aged, urban Chinese men.

X. Shu, Y. Xiang, W. Zheng, 2010, Metabolic syndrome and related disorders.

Apolipoprotein AI as therapy for atherosclerosis: does the future of preventive cardiology include weekly injections of the HDL protein?

M. Linton, S. Fazio, 2003, Molecular interventions.

ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects.

M. Linton, S. Fazio, D. Dove, 2005, American journal of physiology. Cell physiology.

Contents of volumes 263, 264, 266–289

Robert V Farese, W. A. Bradley, S. Grundy, 1998, Methods in Enzymology.

Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice

M. Linton, C. Flynn, J. Stafford, 2022, Frontiers in Physiology.

Sex-Specific Parental Effects on Offspring Lipid Levels

Rafal S. Sobota, Scott M. Williams, D. Schlessinger, 2015, Journal of the American Heart Association.

Selective macrophage ascorbate deficiency suppresses early atherosclerosis.

M. Linton, V. Babaev, Liying Li, 2011, Free radical biology & medicine.

6-Mercaptopurine, monocytes, and atherosclerosis.

M. Linton, S. Fazio, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Debate: "How low should LDL cholesterol be lowered?" Viewpoint: "It doesn't need to be very low"

M. Linton, S. Fazio, 2001, Current controlled trials in cardiovascular medicine.

Care = Cholesterol and Associated Events; Chd = Coronary Heart Disease; Hdl = High-density Lipoprotein; Lipid = Long-term Intervention with Introduction

M. Linton, S. Fazio, 2022 .

Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL[S]

M. Linton, P. Yancey, S. Fazio, 2015, Journal of Lipid Research.

Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice[S]

M. Linton, A. Fogo, S. Fazio, 2014, Journal of Lipid Research.

High-Density Lipoproteins in Kidney Disease

K. Vickers, M. Linton, V. Kon, 2021, International journal of molecular sciences.

The FoxOs are in the ApoM house

M. Linton, P. Yancey, Jonathan D. Brown, 2022, The Journal of clinical investigation.

Mechanism of Down-regulation of RNA Polymerase III-transcribed Non-coding RNA Genes in Macrophages by Leishmania*

M. Linton, S. Fazio, I. Willis, 2010, The Journal of Biological Chemistry.

Premature coronary-artery atherosclerosis in systemic lupus erythematosus.

Paolo Raggi, C Michael Stein, N. Olsen, 2003, The New England journal of medicine.

Increased Cerebral Cortical Lipid Peroxidation and Abnormal Phospholipids in Aged Homozygous apoE-Deficient C57BL/6J Mice

T. Montine, J. Morrow, M. Linton, 1999, Experimental Neurology.

Cyclooxygenase products and atherosclerosis.

M. Linton, S. Fazio, 2008, Drug discovery today. Therapeutic strategies.

High-density lipoprotein therapeutics and cardiovascular prevention.

M. Linton, S. Fazio, 2010, Journal of clinical lipidology.

Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages.

M. Linton, V. Babaev, L. Gleaves, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Targeting cardiovascular risk in patients with diabetes: management of dyslipidemia

M. Linton, S. Fazio, Y. S. Ali, 2008, Current opinion in endocrinology, diabetes, and obesity.

Self-association of human PCSK9 correlates with its LDLR-degrading activity.

Lei Ding, Shenfeng Qiu, E. Weeber, 2008, Biochemistry.

Insights into Atherosclerosis Using Nanotechnology

M. Linton, F. Haselton, S. Fazio, 2010, Current atherosclerosis reports.

Class A scavenger receptors, macrophages, and atherosclerosis

M. Linton, S. Fazio, M F Linton, 2001, Current opinion in lipidology.

Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis

M. Linton, C. Stein, S. Fazio, 2018, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.

Oral retinoids and plasma lipids

M. Linton, S. Fazio, Jessica Lilley, 2013, Dermatologic therapy.

Stability and Reliability of Plasma Level of Lipid Biomarkers and Their Correlation with Dietary Fat Intake

X. Shu, Y. Xiang, W. Zheng, 2008, Disease markers.

Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism

T. Ikizler, M. Linton, H. Tao, 2018, BMC Nephrology.

Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High‐Density Lipoprotein–Enriched Serum in Rheumatoid Arthritis

S. L. Bridges, K. Vickers, M. Linton, 2016, Arthritis & rheumatology.

High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages

K. Vickers, M. Linton, T. Miida, 2023, Journal of lipid research.

Uric acid correlates to oxidation and inflammation in opposite directions in women

N. Rothman, Honglei Chen, X. Shu, 2015, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Lipoprotein Subclasses Determined by Nuclear Magnetic Resonance Spectroscopy and Coronary Atherosclerosis in Patients with Rheumatoid Arthritis

T. Pincus, P. Raggi, M. Linton, 2010, The Journal of Rheumatology.

On the relationship between cholesterol lowering and coronary disease event rate.

M. Linton, S. Fazio, 1998, Circulation.

Evidence of metabolic syndrome in lean children with premature pubarche at diagnosis.

W. Russell, M. Linton, D. Vaughan, 2008, Metabolism: clinical and experimental.

Myeloperoxidase-induced modification of HDL by isolevuglandins inhibits paraoxonase-1 activity

K. Vickers, M. Linton, V. Kon, 2021, The Journal of biological chemistry.

Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis.

P. Raggi, K. Vickers, M. Linton, 2016, IJC metabolic & endocrine.

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

Brian T Palmisano, D. Wasserman, M. Linton, 2017, Molecular metabolism.

Elevated high-density lipoprotein (HDL) levels due to hepatic lipase mutations do not reduce cardiovascular disease risk: another strike against the HDL dogma.

M. Linton, S. Fazio, 2009, The Journal of clinical endocrinology and metabolism.

Elucidation of physico-chemical principles of high-density lipoprotein–small RNA binding interactions

K. Vickers, J. Carr, M. Linton, 2022, The Journal of biological chemistry.

Physico-chemical principles of HDL-small RNA binding interactions

K. Vickers, M. Linton, Q. Sheng, 2021, bioRxiv.

PCSK9 Inhibitor Use in the Real World: Data From the National Patient‐Centered Research Network

Adrian F. Hernandez, J. Bian, J. Puro, 2019, Journal of the American Heart Association.

Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry

J. Knowles, D. Rader, C. Ballantyne, 2023, Journal of the American Heart Association.

Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2023, Circulation.

Targeting Epsins to Inhibit FGF Signaling while Potentiating TGF-β Signaling Constrains Endothelial-to-Mesenchymal-Transition in Atherosclerosis

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, bioRxiv.

Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner.

M. Linton, V. Babaev, S. Fazio, 2011, The Journal of clinical investigation.

Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus.

N. Olsen, E. Wakeland, M. Linton, 2006, Proceedings of the National Academy of Sciences of the United States of America.

HDL Function and Atherosclerosis: Reactive Dicarbonyls as Promising Targets of Therapy

M. Linton, H. Tao, P. Yancey, 2023, Circulation research.

Lipoprotein subclasses and particle size determined by nuclear magnetic resonance spectroscopy in systemic lupus erythematosus

P. Raggi, M. Linton, C. Chung, 2008, Clinical Rheumatology.

Novel Domain Interaction Regulates Secretion of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Protein*

Michelle J. Zhang, M. Linton, S. Fazio, 2011, The Journal of Biological Chemistry.

Abstract 12169: LDL-C Levels and Treatment Patterns Among Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry

J. Knowles, D. Rader, C. Ballantyne, 2015 .

Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection

Wei-Qi Wei, C. Shaffer, J. Mosley, 2019, JAMA network open.

Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity.

M. Linton, V. Babaev, Li-jun Ma, 2011, American journal of physiology. Renal physiology.

Scavenging Reactive Lipids to Prevent Oxidative Injury.

K. Murray, M. Linton, Jiansheng Huang, 2020, Annual review of pharmacology and toxicology.

Correlates of High Serum C-Reactive Protein Levels in a Socioeconomically Disadvantaged Population

X. Shu, W. Zheng, L. Signorello, 2008, Disease markers.

Impaired macrophage trafficking and increased helper T cell recruitment with loss of cadherin-11 in atherosclerotic immune response.

M. Linton, M. Bersi, W. Merryman, 2021, American journal of physiology. Heart and circulatory physiology.

A Genetic Approach to the Association Between PCSK9 and Sepsis

Wei-Qi Wei, C. Shaffer, Q. Feng, 2019, JAMA network open.

Secretion from cell culture of HDL and VLDL bearing apoB-33 with a large internal deletion.

S. Young, V. Schumaker, M. Linton, 1997, Journal of Lipid Research.

Response by Mueller et al to Letter Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages".

M. Linton, S. Fazio, J. Stafford, 2019, Circulation.

Impaired Secretion of Apolipoprotein E2 from Macrophages*

M. Linton, P. Yancey, S. Fazio, 2007, Journal of Biological Chemistry.

Benzo[a]pyrene Potentiates the Pathogenesis of Abdominal Aortic Aneurysms in Apolipoprotein E Knockout Mice

U. Sampson, M. Linton, V. Kon, 2012, Cellular Physiology and Biochemistry.

Statins and Atherosclerotic Lesion Microcalcification: A New Mechanism for Plaque Stability?

J. Carr, M. Linton, J. Terry, 2021, Arteriosclerosis, thrombosis, and vascular biology.

Identification of Small Proline-Rich Repeat Protein 3 as a Novel Atheroprotective Factor That Promotes Adaptive Akt Signaling in Vascular Smooth Muscle Cells

M. Linton, V. Babaev, S. Fazio, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Targeting Epsins by nanotherapy regulates lipid metabolism and promotes ABCG1-mediated cholesterol efflux to fortify atheroma regression

Douglas B. Cowan, M. Linton, Yunzhou Dong, 2022, bioRxiv.

Transgenic mice expressing human apoB100 and apoB48.

Robert V Farese, S. Young, M. Linton, 1994, Current opinion in lipidology.

Reading-frame restoration with an apolipoprotein B gene frameshift mutation.

S. Young, M. Linton, V. Pierotti, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals

J. Ferguson, M. Linton, J. Terry, 2023, medRxiv.

Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection

Wei-Qi Wei, C. Shaffer, J. Mosley, 2019, JAMA network open.

Long runs of adenines and human mutations.

S. Young, M. Linton, M. Raabe, 1998, American journal of medical genetics.

Free fatty acids are associated with metabolic syndrome and insulin resistance but not inflammation in systemic lupus erythematosus

P. Raggi, M. Linton, T. Gebretsadik, 2013, Lupus.

Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion

K. Vickers, M. Linton, Shilin Zhao, 2019, Scientific Reports.

Free fatty acids are associated with insulin resistance but not coronary artery atherosclerosis in rheumatoid arthritis.

P. Raggi, M. Linton, T. Gebretsadik, 2011, Atherosclerosis.

Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor−/− Mice Improves Indices of Cardiometabolic Disease

K. Boyd, M. Linton, P. Yancey, 2019, Scientific Reports.

Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor.

Sherry L. Niessen, A. Gaultier, M. Linton, 2008, Blood.

Are statins diabetogenic?

U. Sampson, M. Linton, S. Fazio, 2011, Current opinion in cardiology.

Dysfunctional high-density lipoprotein in patients on chronic hemodialysis.

T. Ikizler, M. Linton, P. Yancey, 2012, Journal of the American College of Cardiology.

Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

D. Ledbetter, J. Knowles, D. Rader, 2018, Journal of the American College of Cardiology.

Imaging mass spectrometry reveals heterogeneity of proliferation and metabolism in atherosclerosis.

M. Linton, V. Babaev, M. Steinhauser, 2019, JCI insight.

Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis.

J. Oates, M. Linton, V. Babaev, 2008, Cell metabolism.

Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.

J. Savage, M. Linton, P. Yancey, 2015, Antioxidants & redox signaling.

Loss of Plasma Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) After Lipoprotein Apheresis

M. Linton, S. Fazio, H. Tavori, 2013, Circulation research.

Response to Duell et al.

M. Linton, S. Fazio, H. Tavori, 2014, Circulation research.

Murine bone marrow transplantation as a novel approach to studying the role of macrophages in lipoprotein metabolism and atherogenesis.

M. Linton, S. Fazio, Sergio Fazio, 1996, Trends in cardiovascular medicine.

Modification by isolevuglandins, highly reactive (cid:2) -ketoaldehydes, deleteriously alters high-density lipoprotein structure and function

M. Linton, P. Yancey, Linda S. May-Zhang, 2020 .

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters HDL structure and function

M. Linton, P. Yancey, Linda S. May-Zhang, 2018 .

A case of severe acquired hypertriglyceridemia in a 7-year-old girl.

M. Linton, S. Fazio, H. Tavori, 2017, Journal of clinical lipidology.