V. Divoky

发表

Iron chelation and 2‐oxoglutarate‐dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1

V. Korinek, Olga Babosova, K. Kapralova, 2019, Journal of cellular and molecular medicine.

Cdk2 inhibition prolongs G1 phase progression in mouse embryonic stem cells.

P. Doležel, V. Divoky, Zuzana Koledova, 2010, Stem cells and development.

Molecular basis of hereditary iron homeostasis defects

V. Divoky, Monika Horváthová, P. Ponka, 2010, Hematology.

RUNX1 mutations contribute to the progression of MDS due to disruption of antitumor cellular defense: a study on patients with lower-risk MDS

H. Votavova, D. Mikulenková, V. Divoky, 2022, Leukemia.

Polymorphic pattern of the (AT)x(T)y motif at −530 5′ to the β‐globin gene in over 40 patients homozygous for various β‐thalassemia mutations

V. Divoky, T. Huisman, A. Adekile, 1994 .

Polymorphic pattern of the (AT)X(T)Y motif at -530 5' to the beta-globin gene in over 40 patients homozygous for various beta-thalassemia mutations.

V. Divoky, T. Huisman, A. Adekile, 1994, American journal of hematology.

The proteasome inhibitor PS-341 inhibits growth and induces apoptosis in Bcr/Abl-positive cell lines sensitive and resistant to imatinib mesylate.

H. Kantarjian, S. Verstovsek, M. Keating, 2003, Haematologica.

Most pediatric patients with essential thrombocythemia show hypersensitivity to erythropoietin in vitro, with rare JAK2 V617F-positive erythroid colonies.

V. Divoky, J. Starý, V. Mihál, 2008, Leukemia research.

Oxidative DNA Damage, Inflammatory Signature, and Altered Erythrocytes Properties in Diamond-Blackfan Anemia

K. Kapralova, V. Divoky, L. Lanikova, 2020, International journal of molecular sciences.

Delayed hemoglobin switching and perinatal neocytolysis in mice with gain-of-function erythropoietin receptor

H. Votavova, V. Divoky, J. Prchal, 2015, Journal of molecular medicine.

DMT1-Mutant Erythrocytes have Shortened Life Span, Accelerated Glycolysis and Increased Oxidative Stress

K. Kapralova, V. Divoky, D. Doležal, 2013, Cellular Physiology and Biochemistry.

RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling.

K. Kapralova, V. Divoky, J. Prchal, 2014, Blood.

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis

M. Schaller, F. Lang, V. Divoky, 2020, Apoptosis.

Molecular Characterization of β-Thalassemia in the Czech and Slovak Populations: Mediterranean, Asian and Unique Mutations

V. Divoky, D. Pospíšilová, K. Indrák, 2016, Hemoglobin.

Gain of chromosome 2p in chronic lymphocytic leukemia: significant heterogeneity and a new recurrent dicentric rearrangement

V. Divoky, M. Jarošová, Z. Pikalová, 2010, Leukemia & lymphoma.

Sickle cell anemia, sickle cell β-thalassemia, and thalassemia major in Albania: characterization of mutations

V. Divoky, A. Adekile, A. Dimovski, 1994, Human Genetics.

A NEW β°‐THALASSAEMIA NONSENSE MUTATION (CODON 112, T→A) NOT ASSOCIATED WITH A DOMINANT TYPE OF THALASSAEMIA IN THE HETEROZYGOTE

V. Divoky, K. Indrák, T. Huisman, 1993 .

RUNX1 mutations contribute to the progression of MDS due to disruption of antitumor cellular defense: a study on patients with lower-risk MDS

H. Votavova, D. Mikulenková, V. Divoky, 2022, Leukemia.

Erythropoietin Signaling Increases Choroidal Macrophages and Cytokine Expression, and Exacerbates Choroidal Neovascularization

V. Divoky, J. Prchal, M. Hartnett, 2018, Scientific Reports.

Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.

D. Wheeler, Linghua Wang, Olga Babosova, 2016, Blood.

Developmental changes in iron metabolism and erythropoiesis in mice with human gain‐of‐function erythropoietin receptor

K. Kapralova, V. Divoky, Jihyun Song, 2022, American journal of hematology.

Hepcidin levels in Diamond-Blackfan anemia reflect erythropoietic activity and transfusion dependency

V. Divoky, L. Radová, P. Džubák, 2014, Haematologica.

Iron status in patients with pyruvate kinase deficiency: neonatal hyperferritinaemia associated with a novel frameshift deletion in the PKLR gene (p.Arg518fs), and low hepcidin to ferritin ratios

V. Divoky, D. Pospíšilová, K. Indrák, 2014, British journal of haematology.

Erythropoietin-driven signaling ameliorates the survival defect of DMT1-mutant erythroid progenitors and erythroblasts

K. Kapralova, V. Divoky, D. Pospíšilová, 2012, Haematologica.

protein expression and iron uptake Functional consequences of the human DMT1 (SLC11A2) mutation on

V. Divoky, D. Pospíšilová, A. Sheftel, 2013 .

the iron transport pathway in erythroid cells Severe hypochromic microcytic anemia caused by a congenital defect of

V. Divoky, J. Prchal, D. Pospíšilová, 2011 .

Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake.

V. Divoky, D. Pospíšilová, Guangjun Nie, 2005, Blood.

Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells.

V. Divoky, J. Prchal, V. Mihál, 2004, Blood.

Intermittent dosage of imatinib mesylate in CML patients with a history of significant hematologic toxicity after standard dosing

M. Egorin, V. Divoky, M. Jarošová, 2006, Leukemia & lymphoma.

Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin.

V. Divoky, P. Džubák, D. Pospíšilová, 2017, Blood cells, molecules & diseases.

β‐Thalassemia Due to Intronic LINE‐1 Insertion in the β‐Globin Gene (HBB): Molecular Mechanisms Underlying Reduced Transcript Levels of the β‐GlobinL1 Allele

J. Issa, V. Divoky, J. Prchal, 2013, Human mutation.

Partial glutathione reductase deficiency as a cause of diverse clinical manifestations in a family with unstable hemoglobin (Hemoglobin Haná, β63(E7) His-Asn).

P. Doležel, P. Mlejnek, V. Divoky, 2010, Blood cells, molecules & diseases.

Molecular characterization of β-thalassemia in Hungary

V. Divoky, K. Indrák, M. Laub, 1993, Human Genetics.

[New beta0-thalassaemic insertion mutation (CD 7/8, +G) in a Slovak family, associated with the Mediterranean haplotype IX].

J. Hudeček, V. Divoky, K. Indrák, 1999, Vnitrni lekarstvi.

Hb Hradec Kralove (Hb HK) or alpha 2 beta 2 115(G17)Ala-->Asp, a severely unstable hemoglobin variant resulting in a dominant beta-thalassemia trait in a Czech family.

V. Divoky, K. Indrák, T. Huisman, 1993, Hemoglobin.

The T→C mutation at position +96 of the untranslated region 3′ to the terminating codon of the β-globin gene is a rare polymorphism that does not cause a β-thalassemia as previously ascribed

V. Divoky, K. Indrák, E. Baysal, 2004, Human Genetics.

Non‐anemic homozygous βo thalassemia in an African‐American family: Association of high fetal hemoglobin levels with β thalassemia alleles

M. Mrug, V. Divoky, D. Thornley‐Brown, 2001 .

MLL-ENL inhibits polycomb repressive complex 1 to achieve efficient transformation of hematopoietic cells.

J. Hess, V. Divoky, R. Slany, 2011, Cell reports.

Flow cytometric monitoring of the in vitro inhibition of the phosphorylation of CRKL and of SRC family kinases in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors

V. Divoky, M. Jarošová, K. Indrák, 2015, International journal of laboratory hematology.

Advances in Brief Mutation in the ATP-binding Pocket of the ABL Kinase Domain in an STI 571-resistant BCR / ABL-positive Cell Line 1

H. Kantarjian, S. Verstovsek, V. Divoky, 2002 .

Loss of Major DNase I Hypersensitive Sites in Duplicated β‐globin Gene Cluster Incompletely Silences HBB Gene Expression

V. Divoky, J. Prchal, L. Lanikova, 2016, Human mutation.

Identification of e6a2 BCR-ABL fusion in a Philadelphia-positive CML with marked basophilia: implications for treatment strategy.

V. Divoky, Lenka Calabkova, M. Jarošová, 2011, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.