Huijun Sun

Huijun Sun, Zhihao Liu, J. Qin, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters.

Huijun Sun, Y. Kato, Q. Meng, 2010, Drug metabolism and pharmacokinetics.

Benzylpenicillin inhibits the renal excretion of acyclovir by OAT1 and OAT3

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Pharmacological reports : PR.

The oligopeptide transporter 2-mediated reabsorption of entecavir in rat kidney.

Huijun Sun, Q. Meng, Changyuan Wang, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Peptide cotransporter 1 in intestine and organic anion transporters in kidney are targets of interaction between JBP485 and lisinopril in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, Drug metabolism and pharmacokinetics.

Pharmacokinetic Interaction between JBP485 and Cephalexin in Rats

Huijun Sun, Q. Meng, Changyuan Wang, 2010, Drug Metabolism and Disposition.

Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice

Pixu Liu, Huijun Sun, Tingting Shen, 2018, Cellular Physiology and Biochemistry.

Facile synthesis of fluorescent carbon dots from Prunus cerasifera fruits for fluorescent ink, Fe3+ ion detection and cell imaging.

Huijun Sun, Xu Han, Cuicui Sun, 2019, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Organic anion transporters 1 (OAT1) and OAT3 meditated the protective effect of rhein on methotrexate-induced nephrotoxicity

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Protective effects of formononetin against rhabdomyolysis-induced acute kidney injury by upregulating Nrf2 in vivo and in vitro

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016 .

Protective effects of dioscin against cartilage destruction in a monosodium iodoacetate (MIA)-indcued osteoarthritis rat model.

Huijun Sun, Ting Zhang, Mozhen Liu, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Subchronic toxicity study of the total flavonoids from Rosa laevigata Michx fruit in rats.

Huijun Sun, Jinyong Peng, Li-na Xu, 2012, Regulatory toxicology and pharmacology : RTP.

Luteolin attenuates glucocorticoid‐induced osteoporosis by regulating ERK/Lrp‐5/GSK‐3β signaling pathway in vivo and in vitro

Huijun Sun, Xiaodong Ma, Yue Jin, 2018, Journal of cellular physiology.

A stronger reversal effect of the combination of dasatinib and menadione on P-gp-mediated multidrug resistance in human leukemia K562/Adr cell line

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Activation of PGC‐1α via isoliquiritigenin‐induced downregulation of miR‐138‐5p alleviates nonalcoholic fatty liver disease

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Phytotherapy research : PTR.

Pharmacokinetics of phosphocreatine and its active metabolite creatine in the mouse plasma and myocardium

Huijun Sun, Changyuan Wang, Ke-xin Liu, 2014, Pharmacological reports : PR.

Targeting P‐glycoprotein and SORCIN: Dihydromyricetin strengthens anti‐proliferative efficiency of adriamycin via MAPK/ERK and Ca2+‐mediated apoptosis pathways in MCF‐7/ADR and K562/ADR

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

α-Lipoic acid protects HAECs from high glucose-induced apoptosis via decreased oxidative stress, ER stress and mitochondrial injury

Huijun Sun, Jinyong Peng, Yue Jin, 2015 .

Novel amino acid-substituted diphenylpyrimidine derivatives as potent BTK inhibitors against B cell lymphoma cell lines.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Bioorganic & medicinal chemistry.

Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Regulatory toxicology and pharmacology : RTP.

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Inflammation.

Study of interaction of butyl p-hydroxybenzoate with human serum albumin by molecular modeling and multi-spectroscopic method

Xingguo Chen, Huijun Sun, Hongli Chen, 2011 .

Dioscin alleviates lipopolysaccharide-induced inflammatory kidney injury via the microRNA let-7i/TLR4/MyD88 signaling pathway.

Huijun Sun, Jinyong Peng, Y. Qi, 2016, Pharmacological research.

Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression.

Y. Li, Huijun Sun, Ke-xin Liu, 2009, World journal of gastroenterology.

Potent effects of dioscin against obesity in mice

Huijun Sun, Jinyong Peng, Y. Qi, 2015, Scientific Reports.

Overexpression of Lipoprotein Lipase in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Improves Hyperlipidemia and Obesity*

Huijun Sun, George Liu, Jianglin Fan, 2004, Journal of Biological Chemistry.

Effects of calycosin against high‐fat diet‐induced nonalcoholic fatty liver disease in mice

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of gastroenterology and hepatology.

Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, Food & function.

Yangonin protects against estrogen-induced cholestasis in a farnesoid X receptor-dependent manner.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, European journal of pharmacology.

Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Food & function.

Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Toxicology and applied pharmacology.

Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation

Huijun Sun, Q. Meng, Xiaokui Huo, 2016, Acta Pharmacologica Sinica.

Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.

Huijun Sun, Q. Meng, Xiaokui Huo, 2015, Toxicology and applied pharmacology.

Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Food & function.

Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Pharmaceutical Research.

Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Biochemical pharmacology.

Laennec protects murine from concanavalin A-induced liver injury through inhibition of inflammatory reactions and hepatocyte apoptosis.

Huijun Sun, Tao Yang, Changyuan Wang, 2008, Biological & pharmaceutical bulletin.

Overexpression of Lipoprotein Lipase in Transgenic Rabbits Inhibits Diet-induced Hypercholesterolemia and Atherosclerosis*

Huijun Sun, Jianglin Fan, Huayun Deng, 2001, The Journal of Biological Chemistry.

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2019, Acta pharmaceutica Sinica. B.

Protective effect of JBP485 on concanavalin A-induced hepatocyte toxicity in primary cultured rat hepatocytes.

Huijun Sun, Jinyong Peng, Tao Yang, 2008, European journal of pharmacology.

Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, Toxicology and applied pharmacology.

A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases

Shuangyong Sun, Huijun Sun, Jinyong Peng, 2020, Frontiers in Pharmacology.

A rapid PCR method of genotyping LDL receptor mutations in WHHL rabbits.

Huijun Sun, Jianglin Fan, M. Shiomi, 2002, Journal of atherosclerosis and thrombosis.

Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian journal of pharmaceutical sciences.

Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Enhanced aortic atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits expressing lipoprotein lipase.

Huijun Sun, George Liu, Jianglin Fan, 2005, Cardiovascular research.

Targeting Oct2 and P53: Formononetin prevents cisplatin‐induced acute kidney injury

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, Toxicology and applied pharmacology.

Macrophage-Specific Overexpression of Human Matrix Metalloproteinase-12 in Transgenic Rabbits

Y. Sasaguri, Huijun Sun, Lihua Wu, 2004, Transgenic Research.

Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation

Huijun Sun, Jinyong Peng, Y. Qi, 2017, Front. Pharmacol..

Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Tumor Biology.

Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Journal of natural products.

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Chemical biology & drug design.

Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML.

Huijun Sun, Xiaodong Ma, Bin Wu, 2020, Bioorganic chemistry.

Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats.

Huijun Sun, Q. Meng, Xiaokui Huo, 2014, International journal of pharmaceutics.

OAT1 and OAT3: targets of drug-drug interaction between entecavir and JBP485.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3.

Huijun Sun, Jinyong Peng, Q. Meng, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Oxidative medicine and cellular longevity.

Potent effects of dioscin against liver fibrosis

Huijun Sun, Jinyong Peng, Y. Qi, 2015, Scientific Reports.

Anti‐Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics‐integrated experimental study

Huijun Sun, Yue Jin, Q. Meng, 2022, Phytotherapy research : PTR.

Risk assessment and molecular mechanism study of drug-drug interactions between rivaroxaban and tyrosine kinase inhibitors mediated by CYP2J2/3A4 and BCRP/P-gp

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Frontiers in Pharmacology.

Rosmarinic acid exerts an antagonistic effect on vascular calcification by regulating the Nrf2 signalling pathway

Yufeng Fu, Shuangyong Sun, Huijun Sun, 2019, Free radical research.

Protective effects of yangonin from an edible botanical Kava against lithocholic acid‐induced cholestasis and hepatotoxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits.

Huijun Sun, Jianglin Fan, Xiaofei Wang, 2005, Atherosclerosis.

Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70.

Huijun Sun, Jinyong Peng, Y. Qi, 2015, Pharmacological research.

Potent effects of dioscin against hepatocellular carcinoma through regulating TP53‐induced glycolysis and apoptosis regulator (TIGAR)‐mediated apoptosis, autophagy, and DNA damage

Huijun Sun, Jinyong Peng, Y. Qi, 2019, British journal of pharmacology.

CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism

Huijun Sun, Yue Jin, Q. Meng, 2020, Frontiers in Pharmacology.

Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway

Yufeng Fu, Huijun Sun, Jinyong Peng, 2018, Free radical research.

Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating oligopeptide transporter 1 (Pept1).

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.

Huijun Sun, Jinyong Peng, Yue Jin, 2014, Current pharmaceutical biotechnology.

Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Bo Sun, Huijun Sun, Xiaodong Ma, 2019, ChemMedChem.

Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.

Huijun Sun, Zhihao Liu, Q. Meng, 2016, Food & function.

Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Cardiovascular Drugs and Therapy.

Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis.

Huijun Sun, Jinyong Peng, Q. Meng, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Puerarin sensitized K562/ADR cells by inhibiting NF‐κB pathway and inducing autophagy

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Toxicology and applied pharmacology.

Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, International immunopharmacology.

Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines

Huijun Sun, Jinyong Peng, Yue Jin, 2014, Journal of Biomedical Science.

Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade

Huijun Sun, Xiaodong Ma, Yue Jin, 2020, Aging.

Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ‐PPARγ/PGC‐1α signaling pathway

Huijun Sun, Jinyong Peng, Liuchi Bao, 2020, Phytotherapy research : PTR.

Inhibitory effect of 1α,25-dihydroxyvitamin D₃ on excretion of JBP485 via organic anion transporters in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Comparative Inhibitory Effects of Natural Biflavones from Ginkgo against Human CYP1B1 in Recombinant Enzymes and MCF-7 Cells

Hong Yu, Huijun Sun, Q. Meng, 2022, Planta Medica.

Protective effect of Rhein against vancomycin‐induced nephrotoxicity through regulating renal transporters and Nrf2 pathway

Huijun Sun, Xiaodong Ma, Deshi Dong, 2022, Phytotherapy research : PTR.

Icariin promotes directed chondrogenic differentiation of bone marrow mesenchymal stem cells but not hypertrophy in vitro

Huijun Sun, Zhi Wang, Mo-zhen Liu, 2014, Experimental and therapeutic medicine.

Protective effect of cilastatin against diclofenac‐induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, British journal of pharmacology.

Targeting renal OATs to develop renal protective agent from traditional Chinese medicines: Protective effect of Apigenin against Imipenem‐induced nephrotoxicity

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity

Huijun Sun, Q. Meng, Changyuan Wang, 2022, Frontiers in Pharmacology.

Investigating the core microbiota and its influencing factors in traditional Chinese pickles.

Huijun Sun, R. Wu, Junrui Wu, 2021, Food research international.

Alpha‐Lipoic Acid Promotes Osteoblastic Formation in H2O2‐Treated MC3T3‐E1 Cells and Prevents Bone Loss in Ovariectomized Rats

Huijun Sun, Yue Jin, Q. Meng, 2015, Journal of cellular physiology.

Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway.

Yongli Wei, Lina Xu, Youwei Xu, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Catalpol attenuates oxidative stress and promotes autophagy in TNF-α-exposed HAECs by up-regulating AMPK

Huijun Sun, Yue Jin, Zhihao Liu, 2017 .

Inhibitory effect of valsartan on the intestinal absorption and renal excretion of bestatin in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Journal of pharmaceutical sciences.

Protective effects of ginsenoside Rg1 against lipopolysaccharide/d‐galactosamine‐induced acute liver injury in mice through inhibiting toll‐like receptor 4 signaling pathway

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, International immunopharmacology.

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Oncotarget.

Protective effect of-lipoic acid on oxidized low density lipoprotein-induced human umbilical vein endothelial cell injury

Huijun Sun, P. Liu, P. Liu, 2011 .

Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis.

Huijun Sun, Q. Meng, Changyuan Wang, 2020, European journal of pharmacology.

The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways

Huijun Sun, Yue Jin, Q. Meng, 2017, Scientific Reports.

Luteolin protects HUVECs from TNF-α-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-κB and MAPK pathways.

Huijun Sun, Yue Jin, Q. Meng, 2014, Journal of atherosclerosis and thrombosis.

JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats.

Huijun Sun, Zhihao Liu, Q. Meng, 2018, Toxicology letters.

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

Huijun Sun, Yue Jin, Zhihao Liu, 2018, Inflammation.

Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro.

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Noncovalent EGFR T790M/L858R inhibitors based on diphenylpyrimidine scaffold: Design, synthesis, and bioactivity evaluation for the treatment of NSCLC.

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, European journal of medicinal chemistry.

Renal transporter OAT1 and PPAR‐α pathway co‐contribute to icaritin‐induced nephrotoxicity

Huijun Sun, Fangjun Wang, Q. Meng, 2022, Phytotherapy research : PTR.

Liver uptake of cefditoren is mediated by OATP1B1 and OATP2B1 in humans and Oatp1a1, Oatp1a4, and Oatp1b2 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Drug Metabolism and Disposition.

Title Involvement of organic anion-transporting polypeptides in the hepatic uptake of dioscin in rat and human

Huijun Sun, Jinyong Peng, Q. Meng, 2013 .

Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-α-induced VCAM-1, ICAM-1and EL expression via the NF-κB pathway.

Huijun Sun, Jinyong Peng, Yue Jin, 2015, Biochimie.

RAPID AND SENSITIVE DETERMINATION OF JBP485 BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY AND ITS APPLICATION IN PHARMACOKINETICS IN RAT

Huijun Sun, Changyuan Wang, Kexin Liu, 2011 .

Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1

Huijun Sun, Jinyong Peng, Zhihao Liu, 2016, Scientific Reports.

Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway

Huijun Sun, Jinyong Peng, Zhihao Liu, 2015, Cancer biology & therapy.

Molecular modeling study of checkpoint kinase 1 inhibitors by multiple docking strategies and prime/MM–GBSA calculation

Huijun Sun, Ying Yang, Juan Du, 2011, J. Comput. Chem..

Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2020, Journal of cellular physiology.

Afatinib Decreases P‐Glycoprotein Expression to Promote Adriamycin Toxicity of A549T Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Journal of cellular biochemistry.

Protective Effects of Calycosin Against CCl4-Induced Liver Injury with Activation of FXR and STAT3 in Mice

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Pharmaceutical Research.

Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Cellular Physiology and Biochemistry.

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Huijun Sun, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Hepatoprotective effect of rhein against methotrexate‐induced liver toxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis.

Huijun Sun, Jinyong Peng, Y. Qi, 2016, Pharmacological research.

Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.

Huijun Sun, Jinyong Peng, Yue Jin, 2015, Toxicology letters.

Icariin promotes stable chondrogenic differentiation of bone marrow mesenchymal stem cells in self-assembling peptide nanofiber hydrogel scaffolds

Huijun Sun, Kaihua Li, Mozhen Liu, 2018, Molecular medicine reports.

Exploring the molecular basis of dsRNA recognition by NS1 protein of influenza A virus using molecular dynamics simulation and free energy calculation.

Huanxiang Liu, Xiaojun Yao, Dabo Pan, 2011, Antiviral research.

Transgenic Rabbits Expressing Human Apolipoprotein(a) Develop More Extensive Atherosclerotic Lesions in Response to a Cholesterol-Rich Diet

Huijun Sun, Jianglin Fan, S. Marcovina, 2001, Arteriosclerosis, thrombosis, and vascular biology.

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2016, Toxicology and applied pharmacology.

miR-125a-5p ameliorates hepatic glycolipid metabolism disorder in type 2 diabetes mellitus through targeting of STAT3

Huijun Sun, Jinyong Peng, Y. Qi, 2018, Theranostics.

MDR1 and OAT1/OAT3 Mediate the Drug-Drug Interaction between Puerarin and Methotrexate

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Pharmaceutical Research.

Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2016, Toxicology and applied pharmacology.

Potential Anti-Rheumatoid Arthritis Activities and Mechanisms of Ganoderma lucidum Polysaccharides

Huijun Sun, Mozhen Liu, Yukun Zhang, 2023, Molecules.

Apigenin Isolated from the Medicinal Plant Elsholtzia rugulosa Prevents β-Amyloid 25–35-Induces Toxicity in Rat Cerebral Microvascular Endothelial Cells

Huijun Sun, Jianguang Li, L. Hou, 2011, Molecules.

Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice

Huijun Sun, Zhihao Liu, Q. Meng, 2015, Pharmaceutical Research.

Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.

Huijun Sun, Xiaodong Ma, Yue Jin, 2019, Pharmacological research.

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.

Huijun Sun, Zhihao Liu, Q. Meng, 2015, International journal of pharmaceutics.

Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis.

Hajime Mishima, Jianglin Fan, Kotaro Ikeda, 2004, Arthritis and rheumatism.

JBP485, A Dual Inhibitor of Organic Anion Transporters (OATs) and Renal Dehydropeptidase-I (DHP-I), Protects Against Imipenem-Induced Nephrotoxicity

Huijun Sun, Jing Chen, Q. Meng, 2022, Frontiers in Pharmacology.

MDR1 and OAT1/OAT3 Mediate the Drug-Drug Interaction between Puerarin and Methotrexate

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Pharmaceutical Research.

Protective effects of glycyrrhizic acid against non‐alcoholic fatty liver disease in mice

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, European journal of pharmacology.

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance.

Huijun Sun, Y. Chen, K. Hatakeyama, 2005, The American journal of pathology.

Macrophage‐derived MMP‐9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits

Huijun Sun, Jifeng Zhang, Y. Chen, 2020, Journal of cellular and molecular medicine.

Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits.

Jianglin Fan, Xiaofei Wang, Huijun Sun, 2004, The American journal of pathology.

Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.

Huijun Sun, Q. Meng, Changyuan Wang, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Semisynthesis and quantitative structure-activity relationship (QSAR) study of novel aromatic esters of 4'-demethyl-4-deoxypodophyllotoxin as insecticidal agents.

X. Yao, Huijun Sun, M. Lv, 2009, Journal of agricultural and food chemistry.

Substrate-dependent inhibition of hypericin on human carboxylesterase 2: implications for herb-drug combination.

Huijun Sun, Tongyi Dou, J. Chen, 2022, Current drug metabolism.

Chondroprotective effects of alpha-lipoic acid in a rat model of osteoarthritis

Huijun Sun, Mozhen Liu, Zhuodong Fu, 2016, Free radical research.

Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P‐glycoprotein

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Hepatoprotection of yangonin against hepatic fibrosis in mice via farnesoid X receptor activation.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, International immunopharmacology.

Corrigendum to "Dioscin attenuates renal ischemia/reperfusion injury by inhibiting theTLR4/MyD88 signaling pathway via up-regulation of HSP70" [Pharmacol. Res. 100 (2015) 341-352].

Huijun Sun, Jinyong Peng, Y. Qi, 2019, Pharmacological Research.

The integrative analysis of competitive endogenous RNA regulatory networks in osteoporosis

Huijun Sun, Yue Jin, Changyuan Wang, 2022, Scientific Reports.

Naringin regulates cholesterol homeostasis and inhibits inflammation via modulating NF-κB and ERK signaling pathways in vitro.

Huijun Sun, Jinyong Peng, Yue Jin, 2016, Die Pharmazie.

An interspecies study of lipid profiles and atherosclerosis in familial hypercholesterolemia animal models with low-density lipoprotein receptor deficiency.

Huijun Sun, George Liu, Yuhui Wang, 2019, American journal of translational research.

Ursolic acid suppresses IL-6 induced C-reactive protein expression in HepG2 and protects HUVECs from injury induced by CRP.

Huijun Sun, Yue Jin, Ke-xin Liu, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Investigation of the interaction between endocrine disruptor bisphenol A and human serum albumin.

Xingguo Chen, Xiao-ru Wang, Huijun Sun, 2010, Chemosphere.

Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats

Huijun Sun, Q. Meng, Xiaochi Ma, 2012, Peptides.

JBP485 improves gentamicin-induced acute renal failure by regulating the expression and function of Oat1 and Oat3 in rats.

Huijun Sun, Jinyong Peng, Q. Meng, 2013, Toxicology and applied pharmacology.

Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian Journal of Pharmaceutical Sciences.

Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat

Huijun Sun, Jinyong Peng, Q. Meng, 2014, Drug Metabolism and Disposition.

Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, Oxidative medicine and cellular longevity.