Xiaodong Ma

发表

Scutellarin exerts protective effects against atherosclerosis in rats by regulating the Hippo–FOXO3A and PI3K/AKT signaling pathways

Yufeng Fu, Shuangyong Sun, Huijun Sun, 2019, Journal of cellular physiology.

Synthesis and Antitumor Activity of Diosgenin Hydroxamic Acid and Quaternary Phosphonium Salt Derivatives.

Xiaodong Ma, Lin Wang, Maoling Yao, 2022, ACS medicinal chemistry letters.

Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.

Jinyong Peng, Xiaodong Ma, Y. Qi, 2018, Toxicology letters.

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation.

Jinyong Peng, Xiaodong Ma, Y. Qi, 2017, Toxicology.

In situ monitoring of the structural change of microemulsions in simulated gastrointestinal conditions by SAXS and FRET

Jinyong Peng, Xiaodong Ma, Zeyao Tang, 2018, Acta pharmaceutica Sinica. B.

Hepatoprotective effect of ginsenoside Rg1 from Panax ginseng on carbon tetrachloride‐induced acute liver injury by activating Nrf2 signaling pathway in mice

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Environmental toxicology.

Exploiting polypharmacology for improving therapeutic outcome of kinase inhibitors (KIs): An update of recent medicinal chemistry efforts.

Xiaodong Ma, Xiaoqing Lv, Xiaodong Ma, 2018, European journal of medicinal chemistry.

Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors.

E. De Clercq, C. Pannecouque, Xiaodong Ma, 2012, European journal of medicinal chemistry.

Discovery of talmapimod analogues as polypharmacological anti-inflammatory agents

Xiaodong Ma, Mengqi Hu, Caiyun Hou, 2019, Journal of enzyme inhibition and medicinal chemistry.

Molecular pharmacokinetic mechanism of the drug-drug interaction between genistein and repaglinide mediated by P-gp.

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO‐1 pathways

Jinyong Peng, Xiaodong Ma, A. Shopit, 2018, Free radical biology & medicine.

Computational discovery and experimental verification of farnesoid X receptor agonist auraptene to protect against cholestatic liver injury

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, Biochemical pharmacology.

RETRACTED ARTICLE: FABP4 contributes to renal interstitial fibrosis via mediating inflammation and lipid metabolism

Jinyong Peng, Xiaodong Ma, Y. Qi, 2019, Cell Death & Disease.

Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains.

Xiaodong Ma, H. Wang, Ling Zhang, 2011, European journal of medicinal chemistry.

P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Pharmacological reports : PR.

Design, synthesis chalcone derivatives as AdipoR agonist for type 2 diabetes

Xiaodong Ma, Mengqi Hu, Jiaming Li, 2018, Chemical biology & drug design.

Design, synthesis, and biological evaluation of hydroxamic acid-substituted 2,4-diaryl aminopyrimidines as potent EGFRT790M/L858R inhibitors for the treatment of NSCLC.

Xiaodong Ma, Y. Qi, Q. Meng, 2021, Bioorganic chemistry.

Catalpol alleviates adriamycin‐induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, British journal of pharmacology.

OAT1 and OAT3 also mediate the drug-drug interaction between piperacillin and tazobactam.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, International journal of pharmaceutics.

Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro

Jinyong Peng, Xiaodong Ma, Xiaodong Li, 2019, Oxidative medicine and cellular longevity.

Structure-based modification of carbonyl-diphenylpyrimidines (Car-DPPYs) as a novel focal adhesion kinase (FAK) inhibitor against various stubborn cancer cells.

Xiaodong Ma, Zhihao Liu, Changyuan Wang, 2019, European journal of medicinal chemistry.

Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma

Xiaodong Ma, Yabin Cheng, Joshua Zhou, 2017, Oncotarget.

Organic anion transporters 1 (OAT1) and OAT3 meditated the protective effect of rhein on methotrexate-induced nephrotoxicity

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Discovery of novel brain-penetrant GluN2B NMDAR antagonists via pharmacophore-merging strategy as anti-stroke therapeutic agents.

Xiaodong Ma, Qihua Zhu, Mengqi Hu, 2021, European journal of medicinal chemistry.

Protective effects of formononetin against rhabdomyolysis-induced acute kidney injury by upregulating Nrf2 in vivo and in vitro

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016 .

Luteolin attenuates glucocorticoid‐induced osteoporosis by regulating ERK/Lrp‐5/GSK‐3β signaling pathway in vivo and in vitro

Huijun Sun, Xiaodong Ma, Yue Jin, 2018, Journal of cellular physiology.

A stronger reversal effect of the combination of dasatinib and menadione on P-gp-mediated multidrug resistance in human leukemia K562/Adr cell line

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Discovery of a series of N-(5-(quinolin-6-yl)pyridin-3-yl)benzenesulfonamides as PI3K/mTOR dual inhibitors.

Xiaodong Ma, Xiaoqing Lv, Jiankang Zhang, 2017, European journal of medicinal chemistry.

Targeting P‐glycoprotein and SORCIN: Dihydromyricetin strengthens anti‐proliferative efficiency of adriamycin via MAPK/ERK and Ca2+‐mediated apoptosis pathways in MCF‐7/ADR and K562/ADR

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

Novel amino acid-substituted diphenylpyrimidine derivatives as potent BTK inhibitors against B cell lymphoma cell lines.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Bioorganic & medicinal chemistry.

Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Regulatory toxicology and pharmacology : RTP.

Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Effects of calycosin against high‐fat diet‐induced nonalcoholic fatty liver disease in mice

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of gastroenterology and hepatology.

Hepatoprotection of auraptene from the peels of citrus fruits against 17α-ethinylestradiol-induced cholestasis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, Food & function.

Yangonin protects against estrogen-induced cholestasis in a farnesoid X receptor-dependent manner.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, European journal of pharmacology.

Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Food & function.

Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Toxicology and applied pharmacology.

Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.

Jia Li, Li Tang, Yongzhou Hu, 2013, Bioorganic & medicinal chemistry.

Soluplus®/TPGS mixed micelles for co-delivery of docetaxel and piperine for combination cancer therapy

Xiaodong Ma, Jianping Wu, Youwei Xu, 2020, Pharmaceutical development and technology.

Design, synthesis, and biological evaluation of cyano-substituted 2,4-diarylaminopyrimidines as potent JAK3 inhibitors for the treatment of B-cell lymphoma.

Xiaodong Ma, Yue Jin, Bin Wu, 2021, Bioorganic chemistry.

JAK3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2019, Bioorganic chemistry.

Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian journal of pharmaceutical sciences.

SAR study culminates in a series of HDAC6 selective inhibitors featuring Schisandrin C-analogous Cap as potential immunomodulatory agents for cancer therapy.

Xiaodong Ma, Xiaoqing Lv, Jian Guo, 2022, Bioorganic chemistry.

Targeting Oct2 and P53: Formononetin prevents cisplatin‐induced acute kidney injury

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, Toxicology and applied pharmacology.

Synthesis and Antibacterial Activity of Novel 4″‐O‐Carbamoyl Erythromycin‐A Derivatives

Xiaodong Ma, Shutao Ma, B. Jiao, 2010, Archiv der Pharmazie.

Discovery of traditional Chinese medicine monomers and their synthetic intermediates, analogs or derivatives for battling P-gp-mediated multi-drug resistance.

Xiaodong Ma, Mengqi Hu, Jiaming Li, 2018, European journal of medicinal chemistry.

Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Tumor Biology.

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Chemical biology & drug design.

Synthesis and biological activity of imidazole group-substituted arylaminopyrimidines (IAAPs) as potent BTK inhibitors against B-cell lymphoma and AML.

Huijun Sun, Xiaodong Ma, Bin Wu, 2020, Bioorganic chemistry.

Discovery of novel quinoline-based mTOR inhibitors via introducing intra-molecular hydrogen bonding scaffold (iMHBS): The design, synthesis and biological evaluation.

Qiaojun He, Bo Yang, Yongzhou Hu, 2015, Bioorganic & medicinal chemistry.

Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors.

J. Yu, Xiaodong Ma, Xiaowu Dong, 2018, Journal of medicinal chemistry.

Identification of highly potent BTK and JAK3 dual inhibitors with improved activity for the treatment of B-cell lymphoma.

Xiaodong Ma, Zhihao Liu, Q. Meng, 2018, European journal of medicinal chemistry.

Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

Jinyong Peng, Xiaodong Ma, Li-na Xu, 2017, European journal of medicinal chemistry.

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Jinyong Peng, Xiaodong Ma, Zhihao Liu, 2017, European journal of medicinal chemistry.

Conformationally restricted quinazolone derivatives as PI3Kδ-selective inhibitors: the design, synthesis and biological evaluation.

Xiaodong Ma, Guochen Zhong, Xiaoqing Lv, 2019, MedChemComm.

Rosmarinic acid exerts an antagonistic effect on vascular calcification by regulating the Nrf2 signalling pathway

Yufeng Fu, Shuangyong Sun, Huijun Sun, 2019, Free radical research.

Protective effects of yangonin from an edible botanical Kava against lithocholic acid‐induced cholestasis and hepatotoxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.

Xiaodong Ma, Qihua Zhu, Wenfeng Ye, 2021, European journal of medicinal chemistry.

Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway

Yufeng Fu, Huijun Sun, Jinyong Peng, 2018, Free radical research.

Design, synthesis and biological evaluation of 6-(nitroimidazole-1H-alkyloxyl)-4-anilinoquinazolines as efficient EGFR inhibitors exerting cytotoxic effects both under normoxia and hypoxia.

Xiaodong Ma, Peng Peng, R. Sheng, 2015, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of tetrahydroisoquinoline-based diaryl urea derivatives for suppressing VEGFR-2 signaling

Xiaodong Ma, Mengqi Hu, Jiaming Li, 2019, Anti-cancer drugs.

Resveratrol enhances the protective effects of JBP485 against indomethacin-induced rat intestinal damage in vivo and vitro through up-regulating oligopeptide transporter 1 (Pept1).

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Identification of 3-amidoquinoline derivatives as PI3K/mTOR dual inhibitors with potential for cancer therapy

Xiaodong Ma, Shuyu Zhan, Xiaoqing Lv, 2017 .

Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Bo Sun, Huijun Sun, Xiaodong Ma, 2019, ChemMedChem.

Preparation and Optimization Lipid Nanocapsules to Enhance the Antitumor Efficacy of Cisplatin in Hepatocellular Carcinoma HepG2 Cells

Jinyong Peng, Xiaodong Ma, Zhihao Liu, 2018, AAPS PharmSciTech.

Development of Two Scalable Syntheses of 4-Amino-5-aminomethyl-2-methylpyrimidine: Key Intermediate for Vitamin B1

Xiaodong Ma, Fener Chen, Lei Zhao, 2012 .

Design, synthesis, and biological evaluation of 2-arylamino-4-(piperidin-4-yloxy)pyrimidines as potent EGFRT790M/L858R inhibitors to treat non-small cell lung cancer.

Y. Yang, Xiaodong Ma, Youjun Xu, 2022, Bioorganic & medicinal chemistry.

Dihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies

Xiaodong Ma, Jing Zhao, Bao-jing Zhang, 2019, Pharmaceutical development and technology.

Puerarin sensitized K562/ADR cells by inhibiting NF‐κB pathway and inducing autophagy

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade

Huijun Sun, Xiaodong Ma, Yue Jin, 2020, Aging.

Fenretinide-polyethylene glycol (PEG) conjugate with improved solubility enhanced cytotoxicity to cancer cell and potent in vivo efficacy

Xiaodong Ma, Youwei Xu, Changyuan Wang, 2020, Pharmaceutical development and technology.

Mixed micelles of TPGS and Soluplus® for co-delivery of paclitaxel and fenretinide: in vitro and in vivo anticancer study

Xiaodong Ma, Youwei Xu, Changyuan Wang, 2020, Pharmaceutical development and technology.

Novel 4-Acrylamido-Quinoline Derivatives as Potent PI3K/mTOR Dual Inhibitors: The Design, Synthesis, and in vitro and in vivo Biological Evaluation

Xiaodong Ma, Shuyu Zhan, Baoyue Ding, 2019, Front. Chem..

Therapeutic Versatility of Resveratrol Derivatives

Zhong Zhou, Xiaodong Ma, Xiaochi Ma, 2017, Nutrients.

Adenine: an important drug scaffold for the design of antiviral agents

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2015, Acta pharmaceutica Sinica. B.

Protective effect of Rhein against vancomycin‐induced nephrotoxicity through regulating renal transporters and Nrf2 pathway

Huijun Sun, Xiaodong Ma, Deshi Dong, 2022, Phytotherapy research : PTR.

Synthesis and Anti‐HIV Activity of Aryl‐2‐[(4‐cyanophenyl)amino]‐4‐pyrimidinone hydrazones as Potent Non‐nucleoside Reverse Transcriptase Inhibitors

C. Pannecouque, Xiaodong Ma, J. Balzarini, 2011, ChemMedChem.

Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs.

C. Pannecouque, Xiaodong Ma, J. Balzarini, 2011, Bioorganic & medicinal chemistry.

WITHDRAWN: Structure optimizations of the novel benzophenone derivatives as potential HIV-1 inhibitors

Xiaodong Ma, Yong-tang Zheng, Changyuan Wang, 2016 .

Benzophenone Derivatives : a Novel Scaffold as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Xiaodong Ma, Jiasheng Xu, Zhendong Song, 2016 .

Identification of the novel N-phenylbenzenesulfonamide derivatives as potent HIV inhibitors

Xiaodong Ma, Yong-tang Zheng, Changyuan Wang, 2015 .

Synthesis, structure-activity relationships, and docking studies of N-phenylarylformamide derivatives (PAFAs) as non-nucleoside HIV reverse transcriptase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Liu-meng Yang, 2012, European journal of medicinal chemistry.

Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs.

E. De Clercq, C. Pannecouque, Xiaodong Ma, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Liu-meng Yang, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Liu-meng Yang, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of naphthyl phenyl ethers (NPEs) as novel nonnucleoside HIV-1 reverse transcriptase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Liu-meng Yang, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of HQCAs with aryl or benzyl substituents on N-1 position as potential HIV-1 integrase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Liu-meng Yang, 2011, Bioorganic & medicinal chemistry.

Biotransformation of resibufogenin by Actinomucor elegans and the cytotoxicity of the resulting metabolites

Xiaodong Ma, Xiaochi Ma, Xiaokui Huo, 2014 .

Design, synthesis and biological evaluation of pyrazol-furan carboxamide analogues as novel Akt kinase inhibitors.

Bo Yang, Yongzhou Hu, Xiaodong Ma, 2016, European journal of medicinal chemistry.

Covalent binding design strategy: A prospective method for discovery of potent targeted anticancer agents.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2017, European journal of medicinal chemistry.

Synthesis, Crystal Structure and Biological Evaluation of Novel 2-Phenylthiazole Derivatives as Multi-Targeting Agents to Treat Alzheimer's Disease

Yu-Wei Liu, Xiaodong Ma, Xiangqing Xu, 2017 .

Protective effect of cilastatin against diclofenac‐induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, British journal of pharmacology.

Targeting renal OATs to develop renal protective agent from traditional Chinese medicines: Protective effect of Apigenin against Imipenem‐induced nephrotoxicity

Huijun Sun, Xiaodong Ma, Q. Meng, 2020, Phytotherapy research : PTR.

Synthesis and Evaluation of 5-Benzyl-1,3,4-Thiadiazole Derivatives as Acetylcholinesterase Inhibitors

Yu-Wei Liu, Xiaodong Ma, Huichun Zhu, 2017 .

Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors.

Bo Yang, Xiaodong Ma, Yongzhou Hu, 2015, European journal of medicinal chemistry.

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Xiaodong Ma, Q. Meng, Changyuan Wang, 2017, European journal of medicinal chemistry.

Improvement of the solubility, photostability, antioxidant activity and UVB photoprotection of trans-resveratrol by essential oil based microemulsions for topical application

Xiaodong Ma, Zhihao Liu, Zeyao Tang, 2018, Journal of Drug Delivery Science and Technology.

Design, synthesis, and evaluation of genipin derivatives for the treatment of Alzheimer's Disease

Yang Zhang, Xiaodong Ma, Jiaming Li, 2018, Chemical biology & drug design.

Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation.

Jida Wang, Xiaodong Ma, Yi Fang, 2011, European journal of medicinal chemistry.

Novel dual small-molecule HIV inhibitors: scaffolds and discovery strategies.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2014, Current pharmaceutical design.

Metabolic profile and structure–activity relationship of resveratrol and its analogs in human bladder cancer cells

Xiaodong Ma, Jinan Wang, Guangyuan Zhang, 2019, Cancer Management and Research.

Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells.

Jinyong Peng, Xiaodong Ma, Xiaodong Li, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Xiaodong Ma, Yue Jin, Xu Han, 2016, European journal of medicinal chemistry.

Phosphocreatine attenuates endoplasmic reticulum stress-mediated hepatocellular apoptosis ameliorates insulin resistance in diabetes model.

Jinyong Peng, Xiaodong Ma, Xiaodong Li, 2018, Biochemical and biophysical research communications.

Differential sensitivities of bladder cancer cell lines to resveratol are unrelated to its metabolic profile

Xiaodong Ma, Hong Li, Mo-li Wu, 2017, Oncotarget.

Novel quinoline-derived mTOR inhibitors with remarkable enzymatic and cellular activities: design, synthesis and biological evaluation

Qiaojun He, Bo Yang, Yongzhou Hu, 2016 .

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Xiaodong Ma, Youwen Zhou, Changyuan Wang, 2016, Journal of medicinal chemistry.

7‐O‐geranylquercetin‐induced autophagy contributes to apoptosis via ROS generation in human non‐small cell lung cancer cells

Xiaodong Ma, Changyuan Wang, Yanyan Jiang, 2017, Life sciences.

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Jinyong Peng, Xiaodong Ma, Yue Jin, 2016, Bioorganic & medicinal chemistry.

Anticancer effect of SZC015 on pancreatic cancer via mitochondria‐dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo

Jinyong Peng, Xiaodong Ma, Zeyao Tang, 2018, Journal of cellular physiology.

Preparation and Optimization Lipid Nanocapsules to Enhance the Antitumor Efficacy of Cisplatin in Hepatocellular Carcinoma HepG2 Cells

Jinyong Peng, Xiaodong Ma, Zhihao Liu, 2018, AAPS PharmSciTech.

Design, synthesis and biological evaluation of sulfonamide-substituted diphenylpyrimidine derivatives (Sul-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with antitumor activity.

Xiaodong Ma, Zhihao Liu, Changyuan Wang, 2017, Bioorganic & medicinal chemistry.

Protective effects of ginsenoside Rg1 against lipopolysaccharide/d‐galactosamine‐induced acute liver injury in mice through inhibiting toll‐like receptor 4 signaling pathway

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, International immunopharmacology.

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2016, Oncotarget.

Synthesis and biological evaluation of N-(benzene sulfonyl)acetamide derivatives as anti-inflammatory and analgesic agents with COX-2/5-LOX/TRPV1 multifunctional inhibitory activity.

Xiaodong Ma, Zhaoxing Chu, Jiaming Li, 2022, Bioorganic & medicinal chemistry letters.

Identification of 2(1H)-pyrimidinones as potential EGFR T790M inhibitors for the treatment of gefitinib-resistant non-small cell lung cancer.

Xiaodong Ma, Changyuan Wang, Guoping Huang, 2019, Bioorganic chemistry.

The synthesis of 4-arylamido-2-arylaminoprimidines as potent EGFR T790M/L858R inhibitors for NSCLC.

Xiaodong Ma, Kexin Liu, Tong Wang, 2018, Bioorganic & medicinal chemistry.

New acrylamide-substituted quinazoline derivatives with enhanced potency for the treatment of EGFR T790M-mutant non-small-cell lung cancers.

Wenjuan Liu, Xiaodong Ma, Zhihao Liu, 2018, Bioorganic chemistry.

Novel Selective and Potent EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Non-Small Cell Lung Cancer

Xiaodong Ma, Yue Jin, Zeyao Tang, 2016, Molecules.

Furthering the design and the discovery of small molecule ATP-competitive mTOR inhibitors as an effective cancer treatment

Yongzhou Hu, Xiaodong Ma, Xiaoqing Lv, 2013, Expert opinion on drug discovery.

Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies.

Yongzhou Hu, Xiaodong Ma, R. Sheng, 2019, European journal of medicinal chemistry.

Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro.

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2019, Acta pharmaceutica Sinica. B.

Noncovalent EGFR T790M/L858R inhibitors based on diphenylpyrimidine scaffold: Design, synthesis, and bioactivity evaluation for the treatment of NSCLC.

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, European journal of medicinal chemistry.

Design and synthesis of diphenylpyrimidine derivatives (DPPYs) as potential dual EGFR T790M and FAK inhibitors against a diverse range of cancer cell lines.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2019, Bioorganic chemistry.

Liver uptake of cefditoren is mediated by OATP1B1 and OATP2B1 in humans and Oatp1a1, Oatp1a4, and Oatp1b2 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2017 .

Synthesis of diosgenyl quaternary ammonium derivatives and their antitumor activity

Xiaodong Ma, Zhizheng Zhao, Lin Wang, 2020, Steroids.

Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS‐dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells

Jinyong Peng, Xiaodong Ma, Zeyao Tang, 2017, Cell biology international.

Novel Quinazoline Derivatives Bearing Various 4‐Aniline Moieties as Potent EGFR Inhibitors with Enhanced Activity Against NSCLC Cell Lines

Xiaodong Ma, Bin Wu, Youwen Zhou, 2016, Chemical biology & drug design.

Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2020, Journal of cellular physiology.

Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.

Xiaodong Ma, Jiaming Li, Shihui Qian, 2022, European journal of medicinal chemistry.

Afatinib Decreases P‐Glycoprotein Expression to Promote Adriamycin Toxicity of A549T Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Journal of cellular biochemistry.

Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, Cellular Physiology and Biochemistry.

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Huijun Sun, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Discovery of Novel Bruton's Tyrosine Kinase (BTK) Inhibitors Bearing a N,9-Diphenyl-9H-purin-2-amine Scaffold.

Xiaodong Ma, Changyuan Wang, Jinyong Peng, 2016, ACS medicinal chemistry letters.

Hepatoprotective effect of rhein against methotrexate‐induced liver toxicity

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2018, European journal of pharmacology.

Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer: The SARs investigation and PK evaluation.

Xiaodong Ma, X. Liang, Yuqing Chen, 2020, European journal of medicinal chemistry.

Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression

Xiaodong Ma, Jihong Yao, Yan Zhao, 2020, Molecular therapy. Nucleic acids.

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate.

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2016, Toxicology and applied pharmacology.

Phosphamide-containing diphenylpyrimidine analogues (PA-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with enhanced activity against pancreatic cancer cell lines.

Xiaodong Ma, Bin Wu, Changyuan Wang, 2017, Bioorganic & medicinal chemistry.

C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFRT790M mutant.

Jinyong Peng, Xiaodong Ma, Q. Meng, 2017, Bioorganic & medicinal chemistry.

Synthesis, characterization, crystal structure and urease-inhibition activities of three 2-phenylthiazole derivatives

Yu-Wei Liu, Xiaodong Ma, Zong-Ming Tang, 2018, Journal of Molecular Structure.

Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.

Huijun Sun, Xiaodong Ma, Yue Jin, 2019, Pharmacological research.

Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action.

Xiaodong Ma, Yang Li, Ze-yao Tang, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Synthesis, characterization, crystal structures, and the biological evaluation of 2-phenylthiazole derivatives as cholinesterase inhibitors

Yu-Wei Liu, Xiaodong Ma, Jiapeng Su, 2020, Journal of Chemical Research.

Negative regulators of STAT3 signaling pathway in cancers

Xiaodong Ma, Hui Li, Mo-li Wu, 2019, Cancer management and research.

Negative regulators of STAT3 signaling pathway in cancers

Xiaodong Ma, Hui Li, Mo-li Wu, 2019 .

O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.

Xiaodong Ma, Jie Zhu, Y. Zhen, 2015, Chemico-biological interactions.

Protective effects of glycyrrhizic acid against non‐alcoholic fatty liver disease in mice

Huijun Sun, Xiaodong Ma, Zhihao Liu, 2017, European journal of pharmacology.

Effects of Yunanan Baiyao adjunct therapy on postoperative recovery and clinical prognosis of patients with traumatic brain injury: A randomized controlled trial.

G. Xing, Xiaodong Ma, Li-feng Chen, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Administration of Yunnan Baiyao improved clinical prognosis of emergency craniotomy in patients with moderate-to-severe TBI: a randomized controlled trial

G. Xing, Xiaodong Ma, Li-feng Chen, 2020 .

LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.

Xiaodong Ma, Jihong Yao, Yan Hu, 2020, Toxicology and applied pharmacology.

Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed of β‐amino Acids

Jia Li, Yongzhou Hu, Xiaodong Ma, 2014, Chemical biology & drug design.

Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P‐glycoprotein

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Journal of cellular physiology.

Hepatoprotection of yangonin against hepatic fibrosis in mice via farnesoid X receptor activation.

Huijun Sun, Xiaodong Ma, Q. Meng, 2019, International immunopharmacology.

Hybrids of aurantiamide acetate and isopropylated genipin as potential anti‐inflammatory agents: The design, synthesis, and biological evaluation

Xiaodong Ma, Hongwei Wang, Wandong Liu, 2020, Chemical biology & drug design.

Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway.

Jinyong Peng, Xiaodong Ma, A. Shopit, 2020, American journal of translational research.

Design, synthesis and activity evaluation of isopropylsulfonyl-substituted 2,4- diarylaminopyrimidine derivatives as FAK inhibitors for the potential treatment of pancreatic cancer.

Xiaodong Ma, Changyuan Wang, Xu Zheng, 2022, European journal of medicinal chemistry.

Rational Design of Multifunctional Polymeric Nanoparticles Based on Poly(l-histidine) and d-α-Vitamin E Succinate for Reversing Tumor Multidrug Resistance.

Xiaodong Ma, Y. Qi, M. Qiao, 2018, Biomacromolecules.

Design, synthesis and biological evaluation of thienopyridinones as Chk1 inhibitors.

Xiaodong Ma, Peng Peng, Tao Liu, 2014, Bioorganic & medicinal chemistry.

Synthesis, Crystal Structure and Biological Evaluation of Novel 2-Phenylthiazole Derivatives as Butyrylcholinesterase Inhibitors

Yu-Wei Liu, Xiaodong Ma, Fu-jun Yin, 2018, Journal of Chemical Research.

Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, Asian Journal of Pharmaceutical Sciences.

Anticancer mechanisms on pyroptosis induced by Oridonin: New potential targeted therapeutic strategies.

Xiaodong Ma, Zeyao Tang, F. Wang, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Design, Synthesis and Biological Evaluation of Novel (Quinolinyl-3-pyridinyl)benzenesulfonamide-Based Hydroxamic Acids as PI3K and HDAC Dual Targeting Inhibitors

Xiaodong Ma, Wan-jing Ding, Li Shen, 2020, Chinese Journal of Organic Chemistry.

Exploitation of Proximity-Mediated Effects in Drug Discovery: An Update of Recent Research Highlights in Perturbing Pathogenic Proteins and Correlated Issues.

Xiaodong Ma, Xiaoqing Lv, Henian Wang, 2023, Journal of medicinal chemistry.

Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties

Huijun Sun, Xiaodong Ma, Q. Meng, 2021, Oxidative medicine and cellular longevity.

Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies

Xiaodong Ma, Zeyao Tang, E. Qaed, 2023, Global Medical Genetics.

A conjugated mTOR/MEK bifunctional inhibitor as potential polypharmacological anticancer agent: the prototype compound discovery

Xiaodong Ma, Jiaming Li, Qiangqiang Tao, 2020, Medicinal Chemistry Research.

Discovery of novel hybrids of mTOR inhibitor and NO donor as potential anti-tumor therapeutics.

Xiaodong Ma, Fang Zhao, Yang-Gan Wang, 2023, Bioorganic & medicinal chemistry.

Discovery of novel pyrazolopyrimidine derivatives as potent mTOR/HDAC bi-functional inhibitors via pharmacophore-merging strategy.

Xiaodong Ma, Mingkang Zhou, Mingming Zhang, 2021, Bioorganic & medicinal chemistry letters.

Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats

Huijun Sun, Jinyong Peng, Xiaodong Ma, 2018, The Journal of pharmacy and pharmacology.

Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway

Yufeng Fu, Huijun Sun, Jinyong Peng, 2018, Free radical research.

Design, synthesis, and biological evaluation of novel 2-methylpiperazine derivatives as potent CCR5 antagonists.

Xiaodong Ma, Tingjun Hou, Tao Liu, 2015, Bioorganic & medicinal chemistry.

Honokiol Prodrug Nanoparticles Based on In Situ Albumin Binding for Long Circulation and High Tumor Uptake.

Xiaodong Ma, Y. Qi, Youwei Xu, 2021, ACS medicinal chemistry letters.

Discovery of selective HDAC6 inhibitors capped by flavonoid or flavonoid-analogous moieties as anti-cancer therapeutics simultaneously harboring anti-proliferative and immunomodulatory activities.

Xiaodong Ma, Zeng Li, Mingming Zhang, 2022, Bioorganic chemistry.

Identification of novel inhibitors of Aurora A with a 3-(pyrrolopyridin-2-yl)indazole scaffold.

Xiaodong Ma, Tao Liu, Lei Xu, 2015, Bioorganic & medicinal chemistry.

Procyanidins: A promising anti‐diabetic agent with potential benefits on glucose metabolism and diabetes complications

Xiaodong Ma, Zeyao Tang, E. Qaed, 2023, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Significant breakthroughs in search for anti-infectious agents derived from erythromycin A.

Xiaodong Ma, Shutao Ma, 2011, Current medicinal chemistry.

Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS‐dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells

Jinyong Peng, Xiaodong Ma, Zeyao Tang, 2017, Cell biology international.

Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis.

Huijun Sun, Xiaodong Ma, Changyuan Wang, 2019, Bioorganic & medicinal chemistry.

Discovery of 3CLpro inhibitor of SARS-CoV-2 main protease

Xiaodong Ma, Qingqing Rao, Y. Kuang, 2023, Future science OA.

Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Xiaodong Ma, Yong-tang Zheng, Fener Chen, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of benzophenone derivatives as potential HIV-1 inhibitors.

Xiaodong Ma, Changyuan Wang, Kexin Liu, 2017, Medicinal chemistry (Shariqah (United Arab Emirates)).