S. Miyamoto

发表

S. Miyamoto, Shigeki Miyamoto, 2019, Cell Death & Differentiation.

Induction of AP-1 activity by perillyl alcohol in breast cancer cells.

S. Miyamoto, M. Gould, Y. Satomi, 1999, Carcinogenesis.

Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS.

S. Miyamoto, K. Won, H. Ozaki, 2001, American journal of physiology. Gastrointestinal and liver physiology.

A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes

Minoru Yoshida, N. Kudo, S. Miyamoto, 2000 .

Autoregulation of I kappa B alpha activity.

I. Verma, P. Chiao, S. Miyamoto, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II

S. Miyamoto, A. Murphy, J. Brown, 2008, Cell Death and Differentiation.

Role of Autophagy in Cardiac Physiology and Pathophysiology

S. Miyamoto, V. P. Tan, 2018 .

Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer

N. Callander, S. Miyamoto, D. Deming, 2017, The Journal of Immunology.

NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events.

S. Shumway, D. Boothman, S. Miyamoto, 2000, The Journal of biological chemistry.

Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload

S. Miyamoto, J. Sadoshima, A. Shirakabe, 2019, The Journal of Biological Chemistry.

Nuclear and mitochondrial signalling Akts in cardiomyocytes.

Mark A Sussman, S. Miyamoto, Marta Rubio, 2008, Cardiovascular research.

Akt-mediated Cardiomyocyte Survival Pathways Are Compromised by Gαq-induced Phosphoinositide 4,5-Bisphosphate Depletion*

John W. Adams, G. Dorn, S. Miyamoto, 2003, Journal of Biological Chemistry.

Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation

G. Luo, D. Boothman, S. Miyamoto, 2003, Oncogene.

Expanding NFκB and SUMO ties

S. Miyamoto, Moon-hee Lee, 2011, Cell cycle.

Bone marrow stromal cells transcriptionally repress ESR1 but cannot overcome constitutive ESR1 mutant activity.

N. Callander, S. Miyamoto, E. Alarid, 2019, Endocrinology.

A Switch in Distinct IκBα Degradation Mechanisms Mediates Constitutive NF-κB Activation in Mature B Cells1

S. Miyamoto, E. Oltz, B. Seufzer, 2000, The Journal of Immunology.

Covalent Modification of the NF-κB Essential Modulator (NEMO) by a Chemical Compound Can Regulate Its Ubiquitin Binding Properties in Vitro *

J. Coon, S. Miyamoto, Emma E Coughlin, 2014, The Journal of Biological Chemistry.

Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2 + / Calmodulin-Dependent Protein Kinase II Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling Permalink

S. Miyamoto, R. Ross, T. Suetomi, 2018 .

Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II &dgr; Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

S. Miyamoto, J. Brown, R. Ross, 2018, Circulation.

Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals.

S. Miyamoto, V. P. Tan, 2016, Journal of molecular and cellular cardiology.

Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells.

S. Shumway, S. Miyamoto, B. Seufzer, 1998, Molecular and cellular biology.

A switch in distinct I kappa B alpha degradation mechanisms mediates constitutive NF-kappa B activation in mature B cells.

S. Miyamoto, E. Oltz, B. Seufzer, 2000, Journal of immunology.

The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors

S. Miyamoto, Tony T. Huang, S. Suryanarayanan, 2002, Molecular and Cellular Biology.

PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress

S. Miyamoto, A. Mabb, S. Wuerzberger-Davis, 2006, Nature Cell Biology.

Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells.

S. Shumway, S. Miyamoto, M. Gould, 2002, Molecular pharmacology.

RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes.

S. Miyamoto, J. Brown, Cameron S. Brand, 2018, Cellular signalling.

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.

S. Miyamoto, D. J. Roberts, Valerie P. Tan-Sah, 2014, Molecular cell.

Location Matters: Clarifying the Concept of Nuclear and Cytosolic CaMKII Subtypes

D. Bers, S. Miyamoto, J. Brown, 2011, Circulation research.

Different pathways of calcium sensitization activated by receptor agonists and phorbol esters in vascular smooth muscle

S. Miyamoto, H. Ozaki, M. Hori, 1993, British journal of pharmacology.

TAK-ling IKK Activation: “Ub” the Judge

S. Miyamoto, S. Wuerzberger-Davis, 2010, Science Signaling.

Tight coupling between the rate of rise of Ca2+ transient and peak twitch contraction in guinea-pig papillary muscle.

S. Miyamoto, H. Ozaki, M. Hori, 1999, European journal of pharmacology.

A Cytosolic ATM/NEMO/RIP1 Complex Recruits TAK1 To Mediate the NF-κB and p38 Mitogen-Activated Protein Kinase (MAPK)/MAPK-Activated Protein 2 Responses to DNA Damage

M. Kelliher, M. Munson, S. Miyamoto, 2011, Molecular and Cellular Biology.

Rapid formation of hepatic organoid in collagen sponge by rat small hepatocytes and hepatic nonparenchymal cells.

K. Hirata, S. Miyamoto, H. Takeda, 2003, Journal of hepatology.

MAP3K8 kinase regulates myeloma growth by cell‐autonomous and non‐autonomous mechanisms involving myeloma‐associated monocytes/macrophages

C. Mitsiades, N. Callander, S. Miyamoto, 2013, British journal of haematology.

Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma

L. Rui, S. Miyamoto, B. Hwang, 2016, Molecular Cancer Research.

Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation.

Ajit S. Divakaruni, Yusu Gu, N. Dalton, 2015, Circulation research.

Gαq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Gαq mediated hypertrophy

John W. Adams, S. Miyamoto, E. Woodcock, 2006 .

Drp1 and Mitochondrial Autophagy Lend a Helping Hand in Adaptation to Pressure Overload.

S. Miyamoto, J. Brown, 2016, Circulation.

Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma

P. L. Bergsagel, A. Broman, N. Callander, 2015, Cancer Immunology Research.

Dissecting NF-κB signaling induced by genotoxic agents via genetic complementation of NEMO-deficient 1.3E2 cells.

S. Miyamoto, Shawn S. Jackson, 2015, Methods in molecular biology.

Mitophagy as a Protective Mechanism against Myocardial Stress.

S. Miyamoto, J. Sadoshima, Jihoon Nah, 2017, Comprehensive Physiology.

Many faces of NF-kappaB signaling induced by genotoxic stress.

S. Miyamoto, Zhao-Hui Wu, 2007, Journal of molecular medicine.

NF-κB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage

Y. Nakamura, S. Miyamoto, B. Seufzer, 2007, Oncogene.

Inhibition of IkappaBalpha nuclear export as an approach to abrogate nuclear factor-kappaB-dependent cancer cell survival.

S. Shumway, S. Miyamoto, S. O’Connor, 2005, Molecular cancer research : MCR.

PIDD: A Switch Hitter

S. Miyamoto, A. Mabb, Zhao-Hui Wu, 2005, Cell.

NF-κB Activation by Camptothecin

S. Shumway, D. Boothman, S. Miyamoto, 2000, The Journal of Biological Chemistry.

Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.

J. Chun, S. Miyamoto, N. Purcell, 2017, Journal of molecular and cellular cardiology.

Negative inotropic effect of endothelin-1 in the mouse right ventricle.

S. Miyamoto, H. Ozaki, M. Hori, 2000, European journal of pharmacology.

Hormones, Cell Proliferation, and Mammary Carcinogenesis

S. Miyamoto, R. Guzman, S. Nandi, 1992 .

IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation*

B. Weaver, S. Miyamoto, E. Choi, 2015, The Journal of Biological Chemistry.

CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis.

S. Miyamoto, H. Hoffman, T. Suetomi, 2018, JCI insight.

DMD # 8342 1 Cytochrome P 450 Expression of Cultured Rat Small Hepatocytes After Long-Term Cryopreservation

S. Miyamoto, T. Mitaka, J. Kon, 2006 .

Cytochrome P450 Expression of Cultured Rat Small Hepatocytes after Long-Term Cryopreservation

S. Miyamoto, T. Mitaka, J. Kon, 2006, Drug Metabolism and Disposition.

Expression of cytochrome P450 enzymes in hepatic organoid reconstructed by rat small hepatocytes

K. Hirata, S. Miyamoto, T. Mitaka, 2005, Journal of gastroenterology and hepatology.

Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger

S. Miyamoto, Justin D. Yu, 2021, Cells.

Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IκBα degradation in B cells

S. Miyamoto, S. Markovina, S. O’Connor, 2005 .

Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.

R. Neubig, S. Miyamoto, L. Lau, 2014, Journal of molecular and cellular cardiology.

A mechanistic insight into a proteasome-independent constitutive inhibitor κ B α (I κ B α ) degradation and nuclear factor κ B (NF- κ B) activation pathway in WEHI-231 B-cells

S. Shumway, S. Miyamoto, 2004 .

Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes.

Mark A Sussman, N. Gude, S. Miyamoto, 2009, Journal of molecular and cellular cardiology.

CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α.

S. Miyamoto, J. Brown, B. Westenbrink, 2017, Journal of molecular and cellular cardiology.

Initiation and Transduction of Stretch-induced RhoA and Rac1 Activation through Caveolae

S. Miyamoto, J. Brown, S. Kawamura, 2003, Journal of Biological Chemistry.

Immunosuppressant FK506 Activates NF-κB through the Proteasome-mediated Degradation of IκBα

Xiangao Sun, S. Miyamoto, K. Yoshioka, 1999, The Journal of Biological Chemistry.

NF-kappaB is essential for induction of pro-inflammatory cytokine genes by filarial parasitic sheath proteins.

S. Miyamoto, K. Narayanan, A. Balakrishnan, 2000, Molecular immunology.

A Switch in Distinct I kBa Degradation Mechanisms Mediates Constitutive NF-kB Activation in Mature B Cells

S. Miyamoto, E. Oltz, B. Seufzer, 2000 .

Identifying post-translational modifications of NEMO by tandem mass spectrometry after high affinity purification.

J. Coon, S. Miyamoto, Emma E Coughlin, 2013, Protein expression and purification.

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis

S. Miyamoto, E. Sanchez-Lopez, M. Guma, 2019, Front. Immunol..

Evaluating mitochondrial autophagy in the mouse heart.

Å. Gustafsson, R. Kitsis, S. Miyamoto, 2016, Journal of molecular and cellular cardiology.

RhoA protects the mouse heart against ischemia/reperfusion injury.

G. Dorn, R. Lang, S. Miyamoto, 2011, The Journal of clinical investigation.

S1P1 Receptor Localization Confers Selectivity for Gi-mediated cAMP and Contractile Responses*

J. Chun, S. Miyamoto, J. Brown, 2008, Journal of Biological Chemistry.

S. Miyamoto, J. Brown, Olivia M. Yu, 2015, Molecular and Cellular Biology.

Title Myocardin-related transcription factor A and Yes-associated protein exert dual control in G protein-coupled receptor-and RhoA-mediated transcriptional regulation and cell

S. Miyamoto, Olivia M. Yu, 2015 .

RelA life and death decisions.

S. Miyamoto, 2004, Molecular cell.

Targeting apoptotic signalling pathway and pro‐inflammatory cytokine expression as therapeutic intervention in TPE induced lung damage

R. Ezhilarasan, S. Miyamoto, K. Narayanan, 2003, Cell biology international.

CD14‐DEPENDENT ACTIVATION OF NF‐κB BY FILARIAL PARASITIC SHEATH PROTEINS

J. Gern, S. Miyamoto, K. Narayanan, 2002 .

Postrepression Activation of NF- k B Requires the Amino-Terminal Nuclear Export Signal Speciﬁc to I k B a

S. Miyamoto, Tony T. Huang, 2001 .

Evidence for Unique Calmodulin-Dependent Nuclear Factor- (cid:1) B Regulation in WEHI-231 B Cells

S. Shumway, S. Miyamoto, M. Gould, 2001 .

Enhanced IKBot Degradation Is Responsible for Constitutive NF-KB Activity in Mature Murine B-Cell Lines

I. Verma, P. Chiao, S. Miyamoto, 2022 .

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

J. Svaren, S. Miyamoto, D. Jarrard, 2014, PloS one.

Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy.

John W. Adams, S. Miyamoto, E. Woodcock, 2006, Journal of molecular and cellular cardiology.

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

G. Firestein, N. Hay, S. Miyamoto, 2018, Annals of the rheumatic diseases.

Group B Streptococcal β-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function

V. Nizet, M. Hensler, S. Miyamoto, 2008, PloS one.

Effect of the sarcolemmal K(ATP) channel blocker HMR1098 on arrhythmias induced by programmed electrical stimulation in canine old myocardial infarction model: comparison with glibenclamide.

Teruaki Wajima, S. Miyamoto, Y. Nagasawa, 2003, Journal of pharmacological sciences.

Cellular and Molecular Responses to Topoisomerase I Poisons: Exploiting Synergy for Improved Radiotherapy

D. Boothman, T. Kinsella, J. Pink, 2000, Annals of the New York Academy of Sciences.

Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction.

S. Miyamoto, C. Berchtold, S. Wuerzberger-Davis, 2005, Molecular cancer research : MCR.

Incidence of cKi-ras Activation in 7 V-Methyl-. / V-nitrosourea-indiicedMammary Carcinomas in Pituitary-isografted Mice 1

R. Sakthivel, S. Miyamoto, R. Guzman, 2006 .

Slowing Na+ channel inactivation prolongs QT interval and aggravates adrenaline-induced arrhythmias.

S. Miyamoto, K. Hashimoto, N. N. Aye, 2001, Japanese journal of pharmacology.

Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis.

S. Miyamoto, R. Guzman, S. Nandi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

IKKβ Regulates the Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation in MCF-7 Breast Cancer Cells

S. Pazhanisamy, S. Miyamoto, Daohong Zhou, 2011, PloS one.

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

E M Schwarz, I. Verma, E. Schwarz, 1995, Genes & development.

Species- and temperature-dependency of the decrease in myofilament Ca2+ sensitivity induced by beta-adrenergic stimulation.

S. Miyamoto, H. Ozaki, M. Hori, 2001, Japanese journal of pharmacology.

Phase II Trial of Bevacizumab Combined with Low Dose Dexamethasone and Lenalidomide (BEV/REV/DEX) for Relapsed or Refractory Myeloma (MM).

N. Callander, S. Miyamoto, S. Markovina, 2007 .

Augmented acetylcholine‐induced, Rho‐mediated Ca2+ sensitization of bronchial smooth muscle contraction in antigen‐induced airway hyperresponsive rats

S. Miyamoto, Y. Chiba, M. Misawa, 1999, British journal of pharmacology.

Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha.

S. Miyamoto, T. Huang, 2001, Molecular and Cellular Biology.

Expanded Nuclear Roles for IκBs

S. Miyamoto, P. W. Bates, Paul W. Bates, 2004, Science's STKE.

KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs.

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2002, Japanese journal of pharmacology.

Immunoregulatory roles of versican proteolysis in the myeloma microenvironment.

N. Callander, S. Miyamoto, P. Hematti, 2016, Blood.

Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma

Aussie Suzuki, S. Miyamoto, S. Wuerzberger-Davis, 2022, Life Science Alliance.

Mechanisms and Models for Elucidating the Cardiac Effects of Sphingosine 1‐Phosphate (S1P)

S. Miyamoto, N. Purcell, J. Brown, 2013 .

Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue

S. Miyamoto, A. Murphy, J. Brown, 2009, Journal of bioenergetics and biomembranes.

Does Cl-/HCO3- exchange play an important role in reperfusion arrhythmias in rats?

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2003, European Journal of Pharmacology.

Calcium movements, distribution, and functions in smooth muscle.

M Hori, S. Miyamoto, K. Won, 1997, Pharmacological reviews.

Many faces of NF-κB signaling induced by genotoxic stress

S. Miyamoto, Zhao-Hui Wu, 2007, Journal of Molecular Medicine.

Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure.

Mark A Sussman, Youngil Lee, Å. Gustafsson, 2013, Genes & development.

TPL2 kinase regulates the inflammatory milieu of the myeloma niche.

P. L. Bergsagel, N. Callander, S. Miyamoto, 2014, Blood.

Molecular Linkage Between the Kinase ATM and NF-κB Signaling in Response to Genotoxic Stimuli

R. Tibbetts, S. Miyamoto, Zhao-Hui Wu, 2006, Science.

Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.

S. Miyamoto, K. Shibata, T. Kusafuka, 1983, Cancer research.

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

S. Miyamoto, Shigeki Miyamoto, D. J. Roberts, 2014, Cell Death and Differentiation.

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

S. Miyamoto, S Miyamoto, D J Roberts, 2015, Cell Death and Differentiation.

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

J. Greenbaum, F. Furnari, A. Rao, 2018, Oncogene.

HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection

S. Miyamoto, V. P. Tan, 2015, Autophagy.

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.

C. Lim, M. Salto‐Tellez, P. Tan, 2014, The Journal of clinical investigation.

Ca2+ Dysregulation Induces Mitochondrial Depolarization and Apoptosis

John W. Adams, G. Dorn, S. Miyamoto, 2005, Journal of Biological Chemistry.

Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes*

S. Miyamoto, D. J. Roberts, Valerie P. Tan-Sah, 2013, The Journal of Biological Chemistry.

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.

Zhijian J. Chen, E. Wong, S. Miyamoto, 2010, Molecular cell.

Coordinate modulation of Sp1, NF‐kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation

D. Boothman, T. Davis, S. Planchon, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells.

M. Kelliher, S. Miyamoto, Michelle A Kelliher, 2006, Cancer research.

Epithelial cells release proinflammatory cytokines and undergo c-myc-induced apoptosis on exposure to filarial parasitic sheath protein-Bcl2 mediates rescue by activating c-H-ras

S. Miyamoto, K. Narayanan, A. Balakrishnan, 2000, In Vitro Cellular & Developmental Biology - Animal.

Microscale functional cytomics for studying hematologic cancers.

David J Beebe, Edmond W K Young, D. Beebe, 2012, Blood.

Bortezomib-Resistant Nuclear Factor-κB Activity in Multiple Myeloma Cells

KyungMann Kim, N. Callander, S. Miyamoto, 2008, Molecular Cancer Research.

RhoA/Rho Kinase Up-regulate Bax to Activate a Mitochondrial Death Pathway and Induce Cardiomyocyte Apoptosis*

S. Miyamoto, J. Brown, Dominic P. Del Re, 2007, Journal of Biological Chemistry.

Enhanced G2-M Arrest by Nuclear Factor-κB-Dependent p21waf1/cip1 Induction

S. Miyamoto, C. Berchtold, S. Wuerzberger-Davis, 2005, Molecular Cancer Research.

Postrepression Activation of NF-κB Requires the Amino-Terminal Nuclear Export Signal Specific to IκBα

S. Miyamoto, Tony T. Huang, 2001, Molecular and Cellular Biology.

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B.

I. Verma, M. Maki, S. Miyamoto, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress

S. Miyamoto, Zhao-Hui Wu, Tony T. Huang, 2003, Cell.

Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.

S. Miyamoto, E. Alarid, Christopher Hooper, 2015, Journal of molecular endocrinology.

Quantification of Cellular NEMO Content and Its Impact on NF-κB Activation by Genotoxic Stress

A. Audhya, S. Miyamoto, E. Choi, 2015, PloS one.

Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling.

L. Rui, S. Miyamoto, Shawn S. Jackson, 2015, Experimental cell research.

DNA damage‐dependent NF‐κB activation: NEMO turns nuclear signaling inside out

S. Miyamoto, K. McCool, Kevin W. McCool, 2012, Immunological reviews.

Preneoplastic Event in Mouse Mammary Carcinogenesis Induced In Vitro by N-Methyl-N-Nitrosourea

S. Sukumar, S. Miyamoto, R. Guzman, 2003 .

Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea

S. Sukumar, S. Miyamoto, R. Guzman, 1990, Molecular and cellular biology.

Chemical-Carcinogen-Induced Transformation of Primary Cultures of Mouse Mammary Epithelial Cells Grown inside Collagen Gels

S. Miyamoto, R. Guzman, S. Nandi, 2000 .

Novel approaches in anaplastic thyroid cancer therapy.

T. Prolla, Herb Chen, R. Lloyd, 2014, The oncologist.

CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein

S. Miyamoto, T. Gilmore, Alan T. Yeo, 2018, bioRxiv.

SUMO and NF-κB ties

S. Miyamoto, A. Mabb, 2007, Cellular and Molecular Life Sciences.

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress.

S. Miyamoto, Zhao-Hui Wu, Tony T. Huang, 2003, Cell.

Pim-1 Kinase Protects Mitochondrial Integrity in Cardiomyocytes

Mark A Sussman, N. Gude, R. Gottlieb, 2010, Circulation research.

Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer.

A. Hoffmann, N. López-Bigas, M. Mar Albà, 2013, Cancer cell.

Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells

S. Shumway, S. Miyamoto, B. Seufzer, 1998, Molecular and Cellular Biology.

Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription

H. Favoreel, S. Miyamoto, S. Wuerzberger-Davis, 2022, Journal of virology.

Nuclear Factor-κB Dimer Exchange Promotes a p21waf1/cip1 Superinduction Response in Human T Leukemic Cells

S. Miyamoto, Pei-Yun Chang, 2006, Molecular Cancer Research.

Rel/NF-kappa B/I kappa B story.

I. Verma, S. Miyamoto, Inder M. Verma, 1995, Advances in cancer research.

The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells

S. Miyamoto, E. Abel, Kyung E Sung, 2022, Oncogenesis.

Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma

N. Callander, L. Rui, M. Huynh, 2017, The Journal of Biological Chemistry.

Incidence of c-Ki-ras activation in N-methyl-N-nitrosourea-induced mammary carcinomas in pituitary-isografted mice.

R. Sakthivel, S. Miyamoto, R. Guzman, 1992, Cancer research.

Transfection of activated Ha-ras protooncogenes causes mouse mammary hyperplasia.

G. Firestone, S. Miyamoto, R. Guzman, 1990, Cancer research.

Revisited and Revised: Is RhoA Always a Villain in Cardiac Pathophysiology?

S. Miyamoto, J. Brown, G. Florholmen, 2010, Journal of cardiovascular translational research.

Focal Adhesion Kinase as a RhoA-activable Signaling Scaffold Mediating Akt Activation and Cardiomyocyte Protection*

S. Miyamoto, J. Brown, Dominic P. Del Re, 2008, Journal of Biological Chemistry.

Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution.

N. Callander, S. Miyamoto, J. Warrick, 2022, Integrative biology : quantitative biosciences from nano to macro.

Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution

N. Callander, S. Miyamoto, J. Warrick, 2021, bioRxiv.

IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity

A. Hoffmann, S. Miyamoto, M. Suresh, 2020, The Journal of Immunology.

Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma

K. Young, S. Miyamoto, S. Markovina, 2008, Molecular Cancer.

Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia

S. Miyamoto, V. P. Tan, Eric Y. Ding, 2019, Cell Death & Disease.

Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.

S. Miyamoto, M. Gould, C. Berchtold, 2005, Cancer research.

Alcohol Inhibits a Calcium-Dependent Constitutive Nuclear Factor-K B Pathway

S. Miyamoto, M. Gould, C. Berchtold, 2005 .

Analyze the SUMOylation of IKK γ/NEMO During Genotoxic Stress.

S. Miyamoto, Zhao-Hui Wu, 2021, Methods in molecular biology.

NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.

E. Yeh, G. Gill, S. Miyamoto, 2011, Molecular cell.

Regulation of Constitutive p50/c-Rel Activity via Proteasome Inhibitor-Resistant IκBα Degradation in B Cells

S. Shumway, S. Miyamoto, Shelby O'Connor, 2004, Molecular and Cellular Biology.

Award Number: W81XWH-05-1-0295 TITLE: Characterization of a SUMO Ligase that is Essential for DNA Damage-Induced NF-Kappa B Activation

Principal Investigator, S. Miyamoto, A. Mabb, 2007 .

Calcium-Dependent Regulation of NEMO Nuclear Export in Response to Genotoxic Stimuli

S. Miyamoto, Zhao-Hui Wu, Tony T. Huang, 2006, Molecular and Cellular Biology.

Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.

A. Hoffmann, S. Miyamoto, Candace L. Lynch, 2011, Immunity.

HAPLN1 confers multiple myeloma cell resistance to several classes of therapeutic drugs

I. Ong, N. Callander, M. Huynh, 2022, PloS one.

MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells.

David J Beebe, Edmond W K Young, KyungMann Kim, 2015, Integrative biology : quantitative biosciences from nano to macro.

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage

S. Miyamoto, 2011, Cell Research.

Induction of a pro‐apoptotic ATM–NF‐κB pathway and its repression by ATR in response to replication stress

S. Miyamoto, Zhao-Hui Wu, 2008, The EMBO journal.

A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells.

S. Shumway, S. Miyamoto, Stuart D Shumway, 2004, The Biochemical journal.

Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation.

I. Verma, S. Miyamoto, Inder M. Verma, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines

I. Verma, P. Chiao, S. Miyamoto, 1994, Molecular and cellular biology.

Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

KyungMann Kim, N. Callander, S. Miyamoto, 2010, Molecular Cancer.

Changes in thymidine kinase activity during differentiation of HL-60 leukemic cells.

S. Miyamoto, J. Wu, S. Wertheimer, 1987, Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis.

Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo1

Vrajesh V. Parekh, William C. Florence, S. Miyamoto, 2008, The Journal of Immunology.

Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells.

S. Shumway, S. Miyamoto, Shelby O'Connor, 2004, Molecular and cellular biology.

Neoplastic transformation of mouse mammary epithelial cells by in vitro exposure to N-methyl-N-nitrosourea.

S. Miyamoto, R. Guzman, S. Nandi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

The PEST Domain of IκBα Is Necessary and Sufficient forin Vitro Degradation by μ-Calpain*

S. Shumway, M. Maki, S. Miyamoto, 1999, The Journal of Biological Chemistry.

CYLD: a DUB with many talents.

S. Miyamoto, Zhao-Hui Wu, S. Simonson, 2007, Developmental cell.

SiglecF(HI) Marks Late‐Stage Neutrophils of the Infarcted Heart: A Single‐Cell Transcriptomic Analysis of Neutrophil Diversification

K. King, S. Miyamoto, A. Aguirre, 2021, Journal of the American Heart Association.

Cardiomyocyte calcium and calcium/calmodulin-dependent protein kinase II: friends or foes?

S. Miyamoto, J. Brown, Tong Zhang, 2004, Recent progress in hormone research.

The &dgr;C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure

Tong Zhang, Donald M Bers, Lars S Maier, 2003, Circulation research.

PLCε, PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart

S. Miyamoto, J. Brown, Ju Chen, 2013, Science Signaling.

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.

M. Latronico, D. Catalucci, G. Condorelli, 2010, The Journal of clinical investigation.

Inflammation in non-ischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling.

S. Miyamoto, J. Brown, Shigeki Miyamoto, 2019, American journal of physiology. Heart and circulatory physiology.

Autophagy and cardiac aging

S. Miyamoto, 2019, Cell Death & Differentiation.

Xestospongin C, a selective and membrane‐permeable inhibitor of IP3 receptor, attenuates the positive inotropic effect of α‐adrenergic stimulation in guinea‐pig papillary muscle

S. Miyamoto, H. Ozaki, M. Hori, 2000, British journal of pharmacology.

Mitochondria from Oxidative Stress in the Heart PLC{varepsilon}, PKD1, and SSH1L Transduce RhoA Signaling to Protect

S. Miyamoto, K. Ouyang, S. Xiang, 2013 .

Inhibition of IκBα Nuclear Export as an Approach to Abrogate Nuclear Factor-κB–Dependent Cancer Cell Survival

S. Shumway, S. Miyamoto, Shelby L. O’Connor, 2005, Molecular Cancer Research.

ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ

H. Silljé, S. Miyamoto, R. A. Boer, 2021, International journal of molecular sciences.

A PAR-SUMOnious mechanism of NEMO activation.

S. Miyamoto, K. McCool, 2009, Molecular cell.

PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart

A. Newton, Mark A Sussman, S. Miyamoto, 2010, Circulation research.

ATPase Inhibitor Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ

H. Silljé, S. Miyamoto, R. A. Boer, 2021 .

A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance.

N. Callander, S. Miyamoto, J. Warrick, 2022, Molecular Cancer Research.

Cellular redox status determines sensitivity to BNIP3-mediated cell death in cardiac myocytes.

Youngil Lee, Å. Gustafsson, S. Miyamoto, 2015, American journal of physiology. Cell physiology.

QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide.

S. Miyamoto, K. Hashimoto, N. N. Aye, 2000, European journal of pharmacology.

A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes.

N. Kudo, M. Yoshida, S. Miyamoto, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle

Andrew D McCulloch, Donald M Bers, Eleonora Grandi, 2014, Circulation. Arrhythmia and electrophysiology.

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling

A. McCulloch, S. Miyamoto, Andy Nguyen, 2020, PLoS biology.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

SUMO and NF-kappaB ties.

S. Miyamoto, A. Mabb, 2007, Cellular and molecular life sciences : CMLS.

Splicing and Dicing: A Deeper Dive Into CaMKIIδ and Cardiac Inflammation.

S. Miyamoto, J. Brown, 2022, Circulation research.

Acetyl-l-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network

N. Callander, J. Eickhoff, S. Miyamoto, 2014, Cancer Chemotherapy and Pharmacology.

Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IkappaBalpha degradation in B cells.

S. Miyamoto, S. Markovina, Shelby L. O’Connor, 2005, Experimental cell research.

[43] Ultraviolet cross-linking of DNA binding proteins

I. Verma, S. Miyamoto, K. Cauley, 1995 .

Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs.

S. Miyamoto, Y. Nagasawa, K. Hashimoto, 2005, European journal of pharmacology.

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes

S. Miyamoto, P. Gulko, A. Croft, 2023, Frontiers in immunology.

Pituitary-isografted mice are highly susceptible to MNU-induced mammary carcinogenesis irrespective of the level of alveolar differentiation.

K. Christov, S. Miyamoto, R. Guzman, 1994, Carcinogenesis.

IκBα deficiency imposes a fetal phenotype to intestinal stem cells

L. Espinosa, A. Bigas, S. Miyamoto, 2020, EMBO reports.

Synergistic Co-Targeting of BTK and BCL2 in Mantle Cell Lymphoma

L. Rui, S. Miyamoto, M. Bouchlaka, 2015 .

A new alpha in line between KRAS and NF-κB activation?

S. Miyamoto, Chorom Pak, 2013, Cancer Discovery.

IN THE SPOTLIGHT A New Alpha in Line Between KRAS and NF-kB Activation?

S. Miyamoto, Chorom Pak, 2013 .