K. Botting

发表

Akt signaling as a mediator of cardiac adaptation to low birth weight.

Kimberley C. W. Wang, K. Botting, Song Zhang, 2017, The Journal of endocrinology.

Improving pregnancy outcomes in humans through studies in sheep.

Janna L Morrison, Jack R T Darby, Martin G. Frasch, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

Altered autonomic control of heart rate variability in the chronically hypoxic fetus

C. Lees, K. Botting, B. Allison, 2018, The Journal of physiology.

Fetal growth restriction and the programming of heart growth and cardiac insulin‐like growth factor 2 expression in the lamb

Kimberley C. W. Wang, K. Botting, Song Zhang, 2011, The Journal of physiology.

Low birth weight activates the renin–angiotensin system, but limits cardiac angiogenesis in early postnatal life

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015, Physiological reports.

proliferation kinetics in the fetal sheep heart Myocyte enlargement, differentiation, and

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015 .

Early origins of heart disease: Low birth weight and the role of the insulin‐like growth factor system in cardiac hypertrophy

Kimberley C. W. Wang, K. Botting, Song Zhang, 2012, Clinical and experimental pharmacology & physiology.

Does a growth-restricted fetus have fewer cardiomyocytes than a normally grown fetus?

K. Botting, J. Morrison, 2012 .

Restriction of placental function alters heart development in the sheep fetus.

K. Botting, I. McMillen, J. Morrison, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep1

Kimberley C. W. Wang, K. Botting, D. Brooks, 2012, Biology of reproduction.

Early origins of heart disease: Low birth weight and determinants of cardiomyocyte endowment

K. Botting, D. Brooks, J. Morrison, 2012, Clinical and experimental pharmacology & physiology.

Increased lung prolyl hydroxylase and decreased glucocorticoid receptor are related to decreased surfactant protein in the growth-restricted sheep fetus.

K. Botting, Song Zhang, I. McMillen, 2015, American journal of physiology. Lung cellular and molecular physiology.

Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model

K. Botting, J. Morrison, C. Xian, 2014, International journal of endocrinology.

Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction

A. Murray, K. Botting, A. Logan, 2020, Science Advances.

Embryonic cardioprotection by hydrogen sulphide: studies of isolated cardiac function and ischaemia‐reperfusion injury in the chicken embryo

K. Botting, D. Giussani, Y. Niu, 2020, The Journal of physiology.

Chronic Hypoxia in Ovine Pregnancy Recapitulates Physiological and Molecular Markers of Preeclampsia in the Mother, Placenta, and Offspring

G. Burton, K. Botting, Lin Zhang, 2022, Hypertension.

Melatonin modulates the fetal cardiovascular defense response to acute hypoxia

K. Botting, A. Thakor, B. Allison, 2015, Journal of pineal research.

Altered Cardiovascular Defense to Hypotensive Stress in the Chronically Hypoxic Fetus

K. Botting, A. Thakor, B. Allison, 2020, Hypertension.

The Periconceptional Environment and Cardiovascular Disease: Does In Vitro Embryo Culture and Transfer Influence Cardiovascular Development and Health?

Janna L. Morrison, Kimberley C. W. Wang, K. Botting, 2015, Nutrients.

Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart

E. Camm, K. Botting, A. Sferruzzi-Perri, 2018, Front. Physiol..

The effect of prenatal hypoxia on cardiomyocyte development and postnatal heart health.

K. Botting, 2014 .

Antenatal Steroids and the IUGR Fetus: Are Exposure and Physiological Effects on the Lung and Cardiovascular System the Same as in Normally Grown Fetuses?

K. Botting, Song Zhang, I. McMillen, 2012, Journal of pregnancy.

Maternal and fetal cardiovascular and metabolic effects of intra-operative uterine handling under general anesthesia during pregnancy in sheep

C. Lees, K. Botting, D. Giussani, 2020, Scientific Reports.

Fetal in vivo continuous cardiovascular function during chronic hypoxia

K. Botting, A. Thakor, B. Allison, 2016, The Journal of physiology.

Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus.

K. Botting, J. Morrison, S. Gentili, 2011, Journal of applied physiology.

Contractile and Ca2+-handling properties of the right ventricular papillary muscle in the late-gestation sheep fetus.

K. Botting, J. Morrison, G. Posterino, 2006, Journal of applied physiology.

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults

Kimberley C. W. Wang, K. Botting, D. Brooks, 2018, The Journal of physiology.

Placental Adaptations in Growth Restriction

Claire T. Roberts, Janna L. Morrison, T. Regnault, 2015, Nutrients.

Adverse Intrauterine Environment and Cardiac miRNA Expression

K. Botting, D. Brooks, J. Morrison, 2017, International journal of molecular sciences.

Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system

E. Camm, S. Ozanne, K. Botting, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex- and cause-of-IUGR-specific manner.

J. Nyengaard, K. Botting, Song Zhang, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

Noninvasive high-intensity focused ultrasound treatment of twin-twin transfusion syndrome: A preliminary in vivo study

C. Lees, K. Botting, I. Rivens, 2016, Science Translational Medicine.

Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic

A. David, T. Regnault, K. Botting, 2018, The Journal of physiology.

Maternal and fetal cardiometabolic recovery following ultrasound-guided high-intensity focused ultrasound placental vascular occlusion

C. Lees, K. Botting, B. Allison, 2019, Journal of the Royal Society Interface.

Intervention against hypertension in the next generation programmed by developmental hypoxia

K. Botting, B. Allison, D. Giussani, 2019, PLoS biology.

Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus.

Kimberley C. W. Wang, K. Botting, I. McMillen, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation.

C. Roberts, K. Botting, J. Morrison, 2012, Reproductive toxicology.

Regulation of microRNA during cardiomyocyte maturation in sheep

K. Botting, Song Zhang, I. McMillen, 2015, BMC Genomics.

Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia‐Responsive Genes

J. Nyengaard, K. Botting, I. McMillen, 2014, Journal of the American Heart Association.

Does maternal obesity change cardiomyocyte endowment

J. Nyengaard, K. Botting, J. Morrison, 2013 .

Molecular mechanisms underlying adverse effects of dexamethasone and betamethasone in the developing cardiovascular system

S. Ozanne, K. Botting, J. Derks, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia

C. Roberts, K. Botting, Song Zhang, 2016, Physiological reports.

Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments.

Janna L Morrison, Tak W. Kee, K. Botting, 2008, Journal of biomedical optics.

At the heart of accelerated old matter

K. Botting, D. Giussani, 2017, The Journal of physiology.

model of congenital heart disease before pulmonary vascular remodeling in a lamb Delineating the angiogenic gene expression profile

D. Tosh, Kimberley C. W. Wang, K. Botting, 2015 .

Fetal heart growth: IGF-1 and sex

Kimberley C. W. Wang, K. Botting, D. Brooks, 2009 .

Sex-specific effects of in vitro culture and embryo transfer on cardiac growth in sheep offspring

J. Nyengaard, K. Botting, Song Zhang, 2023, Journal of Molecular and Cellular Cardiology Plus.

Trans-abdominal in vivo placental vessel occlusion using High Intensity Focused Ultrasound

C. Lees, K. Botting, I. Rivens, 2018, Scientific Reports.

Early origins of heart disease: Low birth weight and the role of the insulin‐like growth factor system in cardiac hypertrophy

Kimberley C. W. Wang, K. Botting, Song Zhang, 2012, Clinical and experimental pharmacology & physiology.

Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus.

K. Botting, J. Morrison, B. Muhlhausler, 2010, Placenta.

Fetal in vivo continuous cardiovascular function during chronic hypoxia

K. Botting, A. Thakor, B. Allison, 2016, The Journal of physiology.

MitoQ as an antenatal antioxidant treatment improves markers of lung maturation in healthy and hypoxic pregnancy

K. Botting, B. Allison, D. Giussani, 2023, The Journal of physiology.